СИСТЕМА, РЕГИСТРАТОР И СПОСОБ ПОВЕРХНОСТНОЙ ЭЛЕКТРОМИОГРАФИИ

Группа изобретений относится к медицине, а именно к системе для электромиографии, способу измерения и регистратору электромиограммы. Система содержит первый и второй электроды для контакта с кожей субъекта, заземленный эталонный электрод, регистратор для записи электромиограммы и выходной блок для указания качества контакта кожи с электродом. Первый электрод содержит изолированные друг от друга первую и вторую электродные области. Заземленный эталонный электрод выполнен с возможностью ограничения шума синфазных сигналов и ограничения воздействия синфазных сигналов на первый и второй электроды. Регистратор выполнен с возможностью измерения шума между первой и второй электродными областями для определения качества контакта кожи с первым электродом. При этом получают сигналы от первой и второй электродных областей первого электрода. Выполняют измерение шума между первой и второй электродными областями для определения качества контакта кожи с первым электродом. Регистрируют сигнал электромиографии ...

СПОСОБЫ, СИСТЕМА И УСТРОЙСТВО ДЛЯ ОБНАРУЖЕНИЯ, ДИАГНОСТИКИ И ЛЕЧЕНИЯ НАРУШЕНИЙ БИОЛОГИЧЕСКОГО РИТМА

Изобретение относится к медицинской технике. Представлена система восстановления информации от сердца, представляющей сложное нарушение ритма, связанное с сердцем пациента, для указания источника нарушения сердечного ритма. Сложное нарушение ритма может подвергаться лечению при помощи воздействия энергией для изменения источника нарушения ритма. Изобретение позволяет использовать сигналы с низкой достоверностью для локализации причин нарушений сердечного ритма. 20 з.п. ф-лы, 25 ил.

СИСТЕМА И СПОСОБ СТАБИЛИЗАЦИИ ОПТИЧЕСКОГО ОПРЕДЕЛЕНИЯ ФОРМЫ

... 1. Способ определения формы посредством оптического волокна, содержащий этапы, на которых:собирают (610) данные о форме от оптоволоконного устройства (104) определения формы;выполняют (620) тестирование данных о форме для определения позиций данных, которые превышают приемлемое пороговое значение, на основании геометрических ожиданий данных о форме;отклоняют (640) данные о форме, соответствующие позициям данных, которые превышают приемлемое пороговое значение; ивоспроизводят (650) приемлемые данные о форме для получения набора данных для стабильного определения формы.2. Способ по п. 1, в котором приемлемое пороговое значение определяют (622) на основании модели (142) определения формы.3. Способ по п. 1, в котором приемлемое пороговое значение определяют (624) на основании ранее собранных данных о форме.4. Способ по п. 1, в котором выполнение тестирования данных о форме включает в себя этап, на котором вычисляют (626) пространственно-временную непрерывность вдоль данных о форме.5. Способ ...

ИЗМЕРИТЕЛЬНЫЙ АППАРАТ И СПОСОБ ИЗМЕРЕНИЯ

Группа изобретений относится к медицинской технике. Измерительный аппарат включает в себя источник излучения, выполненный с возможностью выдавать излучение в средней инфракрасной области спектра, детектор, выполненный с возможностью облучать объект измерения излучением, выдаваемым из источника излучения, и детектировать отраженное излучение, отражаемое объектом измерения, и устройство измерения уровня глюкозы в крови, выполненное с возможностью измерять уровень глюкозы в крови объекта измерения. В качестве волнового числа измерения уровня глюкозы в крови для измерения уровня глюкозы в крови используется волновое число между множеством волновых чисел пиков поглощения глюкозы. 3 н. и 19 з.п. ф-лы, 50 ил.

ВЫБОР ДЫХАТЕЛЬНОГО ЦИКЛА ДЛЯ АНАЛИЗА

СИСТЕМА НАБЛЮДЕНИЯ СЕРДЕЧНОЙ АКТИВНОСТИ С ИСПОЛЬЗОВАНИЕМ ДАТЧИКОВ ЭЛЕКТРИЧЕСКОГО ПОТЕНЦИАЛА

УСТРОЙСТВО И СПОСОБ ДЛЯ ОПРЕДЕЛЕНИЯ ПОЯВЛЕНИЯ КОМПЛЕКСА QRS В ДАННЫХ ЭКГ

НЕЙРОКОМПЬЮТЕРНЫЙ ИНТЕРФЕЙС, СОДЕЙСТВУЮЩИЙ ТОЧНОМУ ВЫБОРУ ОТВЕТОВ ИЗ МНОЖЕСТВА ВАРИАНТОВ И ИДЕНТИФИКАЦИИ ИЗМЕНЕНИЯ СОСТОЯНИЯ

АВТОМАТИЗИРОВАННЫЕ АНАЛИЗ И РАСШИФРОВКА СПИРОГРАММ

... 1. Способ оценки функции легких субъекта, причем упомянутый способ реализуется в диагностическом устройстве, выполненном с возможностью исполнения одного или более компьютерных программных модулей, и упомянутый способ содержит этапы, на которых:принимают выдыхаемый поток воздуха из дыхательных путей субъекта при выдохе субъекта;измеряют объем выдоха при выдохе субъекта по принятому выдыхаемому потоку воздуха;создают график, представляющий объем выдоха при выдохе, причем график имеет форму;определяют достоверность измерения объема выдоха при выдохе; иоценивают на основе формы графика характеристики функции легких субъекта.2. Способ по п. 1, в котором этап, на котором оценивают характеристики функции легких субъекта, выполняют в зависимости от определения того, что измерение объема выдоха при выдохе является достаточно достоверным.3. Способ по п. 1, в котором этап, на котором определяют достоверность измерения объема выдоха, основан на форме графика.4. Способ по п. 3, в котором этап, на котором ...

СПОСОБ И УСТРОЙСТВО ДЛЯ ОЦЕНКИ НАДЕЖНОСТИ РЕКОМЕНДАЦИИ ОТНОСИТЕЛЬНО РАЗРЯДА ПРИ СЕРДЕЧНО-ЛЕГОЧНОЙ РЕАНИМАЦИИ

УМЕНЬШЕНИЕ ШУМА НА ЭЛЕКТРОКАРДИОГРАММЕ

СИСТЕМА И СПОСОБ ОБНАРУЖЕНИЯ ЗНАЧИМЫХ АРИТМИЧЕСКИХ СОБЫТИЙ ПОСРЕДСТВОМ ФОТОПЛЕТИЗМОГРАММЫ(PPG) И АКСЕЛЕРОМЕТРА

НАДЕЖНЫЙ СБОР ФОТОПЛЕТИЗМОГРАФИЧЕСКИХ ДАННЫХ

УСТРОЙСТВО ДЛЯ ОБНАРУЖЕНИЯ ФИЗИЧЕСКОГО ДВИЖЕНИЯ И СПОСОБ УПРАВЛЕНИЯ УСТРОЙСТВОМ ДЛЯ ОБНАРУЖЕНИЯ ФИЗИЧЕСКОГО ДВИЖЕНИЯ

... 1. Устройство для обнаружения физического движения, которое содержит основной блок, снабженный датчиком ускорения для измерения ускорения упомянутого основного блока и блоком управления, и выполнено с возможностью обнаружения физических движений пользователя, когда упомянутый основной блок установлен на предварительно заданной части пользователя,при этом упомянутый блок управления содержитизмерительный элемент, выполненный с возможностью обнаружения, коснулась ли или нет грунта одна из ног упомянутого пользователя, на основании зарегистрированных значений из упомянутого датчика ускорения,причем в пределах одного цикла передвижения период, в течение которого упомянутый пользователь стоит на первой ноге с момента времени, когда упомянутый измерительный элемент обнаруживает, что упомянутая первая нога коснулась грунта, до момента времени, когда упомянутый измерительный элемент обнаруживает, что вторая нога коснулась грунта, определяется как период первой позиции, ив пределах одного цикла передвижения ...

Haemodynamic monitor with improved filtering

Opto-physiological sensor and method of design

Heart rate and actively monitor system filters

Method, wearable article and assembly

A method (see figure 18) determines an amount of degradation for a wearable article comprising conductive elements. A wearable article is provided (S101) comprising a fabric layer (201, figs 3-5); a sensing component 200 provided on the fabric layer, and a calibration component 300. The sensing component and the calibration component both comprise a length of a first type of conductive material. The method comprises positioning an electronics module on a wearable article such that an interface of the electronics module is communicatively coupled with the calibration component of the wearable article (S102). The method comprises measuring an electrical property of the length of conductive material of the calibration component so as to determine a degree of degradation of the conductive material (S103). Also claimed is a wearable article, such as a smart garment, comprising such a calibration component. As use and washing impact the electrical properties of the conducting element, the calibration ...

Method and system for measuring and displaying biosignal data to a wearer of a wearable article

An electronics module receives biosignals, such as ECG, electrocardiogram, signals, from sensors on a wearable article and processes these signals to provide data and information to a user electronic device, such as a mobile phone. The user electronic device and/or electronics module is operable to determine whether the quality of the signal is above or below a predetermined level and to display a real-time biosignal trace on the user electronic device when the quality of the signal is high. The high-quality signal is also stored on user electronic device. When the signal quality is low, the user electronic device displays a composite trace instead of a real-time trace. The composite signal being composed of the stored high-quality trace modified by a current biosignal characteristic (such as current R-R value). The quality of the signal may be determined by an activity level of the user or motion level such as determining whether the wearer of the electronics module is relatively stationary ...

A METHOD AND APPARATUS FOR VALIDATION OF A BLUTDPRINT SYSTEM

Die Erfindung betrifft ein Verfahren und eine Vorrichtung zur Validierung eines kontinuierlich messenden, nicht-invasiven Blutdruckmesssystems (202), das mit einem plethysmographischen System (203, 204) ausgestattet ist, das geeignet ist – in einer Messphase - ein plethysmographisches Signal v(t) an einer Extremität (101) zu gewinnen, mit einem Regelmechanismus (206) dem das Signal v(t) aus dem plethysmographischen System (203, 204) zugeführt wird, welcher über einen Stellwert u(t) den Anpressdruck pC(t) an der Extremität (201) verändert, und mit einer Auswerteeinheit, welche basierend auf dem resultierenden Anpressdruck pC(t) den Verlauf des arteriellen Blutdrucks pA(t) kontinuierlich bestimmt. Erfindungsgemäß weist das Blutdruckmesssystem (202) eine Einkoppelschnittstelle (209) auf, über die - in einer Validierungs- oder Testphase - ein Signal, abgeleitet von einem zuvor aufgezeichneten Blutdruckverlauf in das Blutdruckmesssystem (202) einkoppelbar ist.

Medical detector and method for detecting extrapotism

Die Erfindung stellt einen medizinischen Detektor (1) und ein Verfahren zum automatischen Erkennen eines Extrapulses (ex) bereit, der auf einen medizinischen Zustand wie Diplophonie hinweisen kann. Der medizinische Detektor (1) umfasst eine Eingabeeinheit (10), die konfiguriert ist, um ein Eingangssignal (d) zu erhalten, wie beispielsweise ein Phonationssignal, wobei das Eingangssignal (d) eine Schwingμng eines medizinischen Messwerts und/oder eine Schwingung eines menschlichen Körperteils, wie beispielsweise eines Stimmritzenbereichs, anzeigt; eine zyklische Pulsfolgenschätzeinheit (20), die zum Abschätzen einer zyklischen Pulsfolgenkomponente (c1) des Eingangssignals (1) konfiguriert ist; eine zyklische Pulsfolgensubtrahiereinheit (20), die konfiguriert ist, um die zyklische Pulsfolgenkomponente (c1) von dem Eingangssignal (d) abzuziehen, um dadurch ein zyklisches Modellfehlersignal (e1) zu erhalten; und eine Extrapulsdetektoreinheit (6, 60), die konfiguriert ist, um einen Extrapuls ( ...

MORE PULSOXIMETER

Verfahren zur Detektion von Artefakten

The method involves dividing a biological signal into several partial signals (11). The amplitude of the partial signal during occurrence of an event is determined (15) according to a number of events. The small remaining amplitude and/or large rejected amplitude of the partial signal are compared with the small remaining amplitudes of the partial signal and/or large rejected amplitudes of the remaining partial signals, for recognizing the artifacts within partial signal. A predetermined threshold value exceeding deviations is stated based on the comparison result.

VERFAHREN UND VORRICHTUNG ZUR BESTIMMUNG DER QUALITÄT EINES ÜBERTRAGUNGSSYSTEMS

Die Erfindung betrifft ein Verfahren und eine Vorrichtung zur Bestimmung der Qualität eines Übertragungssystems in Hinblick auf die Sprachwahrnehmung, bei dem ein Kommunikationsindex berechnet wird, der ein Maß für die Verständlichkeit von Sprachinformation darstellt, indem einer Versuchsperson Testsignale angeboten werden, aus denen MCL (most comfortable level) und UCL (uncomfortable level) bestimmt werden. Eine Steigerung der Genauigkeit kann dadurch erreicht werden, dass die Testsignale auch Tonfolgen zur Bestimmung von zeitlichen Maskierungseffekten beinhalten, die in einem gemeinsamen Berechnungsschritt mit MCL und UCL zur Bestimmung des Kommunikationsindex berücksichtigt werden.

IMPROVED DETECTOR FOR PULSOXIMETERSONDENABLÖSUNG

Confidence of arrhythmia detection

Systems and methods for detecting an arrhythmic event and storing physiological information associated with the detected arrhythmic event are described. A system may include a first detector to detect an arrhythmic event from a physiological signal sensed from a subject, and generate a confidence indicator indicating a confidence level of the detection of the arrhythmic event. If the confidence indicator indicates a relatively high confidence of arrhythmia detection, the system may provide the detected arrhythmic event to a first process for storing the detected arrhythmic event or generating an alert. If the confidence indicator indicates a relatively low confidence of arrhythmia detection, the system may provide the detected arrhythmic event to at least a second process including confirming or rejecting the detected arrhythmic event.

Breath selection for analysis

Methods and systems are described to obtain and analyze a gas sample from a desired section of the breath of a person, while accounting for erratic, episodic or otherwise challenging breathing patterns that may otherwise make the capturing of a gas sample from the desired section of breath difficult. These techniques may provide more reliable, accurate and adequate samples of gas such as end-tidal gas, and ultimately an accurate analysis of the sample captured. - 39- ...

Method, computing device and wearable device for sleep stage detection

In a described embodiment, a method of sleep stage detection is disclosed. The method comprises receiving a first vital sign feature 701a including a plurality of first feature values v ...

Use of electrochemical impedance spectroscopy (EIS) in continuous glucose monitoring

USE OF ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY (EIS) IN CONTINUOUS GLUCOSE MONITORING A method of performing diagnostics on a subcutaneous or implanted sensor having at least one working electrode, comprising: defining a vector containing values associated with one or more electrochemical impedance spectroscopy (EIS)-based parameters and values associated with one or more non-EIS-based parameters; defining a respective threshold value for each of said EIS based parameters and each of said non-EIS-based parameters; performing a first EIS procedure to generate a first set of data for said values associated with the one or more EIS-based parameters; after a calculated time interval, performing a second EIS procedure to generate a second set of data for said values associated with the one or more EIS-based parameters; updating the vector with said first and second sets of data; and monitoring said vector values to determine whether the sensor has lost sensitivity.

MARKING A COMPUTERIZED MODEL OF A CARDIAC SURFACE

Described embodiments include a system that includes an electrical interface and a processor. The processor is configured 5 to receive, via the electrical interface, an electrocardiographic signal from an electrode within a heart of a subject, to ascertain a location of the electrode in a coordinate system of a computerized model of a surface of the heart, to select portions of the model responsively to the ascertained location, such that 0 the selected portions are interspersed with other, unselected portions of the model, and to display the model such that the selected portions, but not the unselected portions, are marked to indicate a property of the signal. Other embodiments are also described. 0c CC~j ...

Methods, systems, and devices for calibration and optimization of glucose sensors and sensor output

A continuous glucose monitoring system may utilize externally sourced information regarding the physiological state and ambient environment of its user for externally calibrating sensor glucose measurements. Externally sourced factory calibration information may be utilized, where the information is generated by comparing metrics obtained from the data used to generate the sensor's glucose sensing algorithm to similar data obtained from each batch of sensors to be used with the algorithm in the future. The output sensor glucose value of a glucose sensor may also be estimated by analytically optimizing input sensor signals to accurately correct for changes in sensitivity, run-in time, glucose current dips, and other variable sensor wear effects. Correction actors, fusion algorithms, EIS, and advanced ASICs may be used to implement the foregoing, thereby achieving the goal of improved accuracy and reliability without the need for blood-glucose calibration, and providing a calibration-free ...

Detecting conditions using heart rate sensors

This relates to methods for measuring irregularities in a' signal and corresponding devices. The devices can include, a PPG sensor unit configured to detect multiple occurrences of a given event in the measured signal(s) over a sampling interval, in some instances, the device can register the occurrences of the events. In some examples;, the device can Include one or more motion sensors configured to detect whether the device is in a low-motion, state. The device may delay initiating measurements when the device Is not in a low-motion state to enhance measurement accuracy. Examples of the disclosure further include resetting the sample procedure based on one or more factors such as the number of non-qualifying 'measurements, in some examples, the -device can be configured to perform both primary and secondary measurements, where the primary measurements can Include readings using a set of operating: conditions different from the secondary measurements.

Methods and systems for improving the reliability of orthogonally redundant sensors

A method of calibrating an orthogonally redundant sensor device for determining the concentration of glucose in a body of a user, said sensor device including at least an electrochemical glucose sensor and an optical glucose sensor, the method comprising: receiving a first signal from the electrochemical glucose sensor; receiving a second signal from the optical glucose sensor; performing a respective integrity check on each of said first and second signals; determining whether the first signal can be calibrated, and whether the second signal can be calibrated, wherein said determination is made based on whether the first signal and the second signal pass or fail their respective integrity checks; if it is determined that the first signal can be calibrated, calibrating said first signal to generate an electrochemical sensor glucose (SG) value; if it is determined that the second signal can be calibrated, calibrating said second signal to generate an optical sensor glucose (SG) value; and ...

NON-INVASIVELY MEASURING HEMODYNAMIC PARAMETERS

Signal quality monitoring and control for a medical device system

Monitoring system

METHOD AND APPARATUS FOR VERIFYING DATA MEASURED BY SEVERAL MEANS IN REAL-TIME

Application of electrochemical impedance spectroscopy in sensor systems, devices, and related methods

A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the ElS-based diagnostics, fusion algorithms, and other processes based on measurement of ElS-based parameters.

Sweat sensing with chronological assurance

Devices that sense sweat and are capable of providing chronological assurance are described. The device (600) uses at least one sensor (620) to measure sweat or its components and to determine a sweat sampling rate. The chronological assurance is determined, at least in part, using the sweat sampling rate. The sweat sampling rate may be determined, at least in part, using a sweat volume (640) and/or a sweat generation rate, both of which may be measured or predetermined.

Methods and systems for improving the reliability of orthogonally redundant glucose sensors

Methods and systems for sensor calibration and sensor glucose (SG) fusion are used advantageously to improve the accuracy and reliability of orthogonally redundant glucose sensor devices, which may include optical and electrochemical glucose sensors. Calibration for both sensors may be achieved via fixed-offset and/or dynamic regression methodologies, depending, e.g., on sensor stability and Isig-Ratio pair correlation. For SG fusion, respective integrity checks may be performed for SG values from the optical and electrochemical sensors, and the SG values calibrated if the integrity checks are passed. Integrity checks may include checking for sensitivity loss, noise, and drift. If the integrity checks are failed, in-line sensor mapping between the electrochemical and optical sensors may be performed prior to calibration. The electrochemical and optical SG values may be weighted (as a function of the respective sensor's overall reliability index (RI)) and the weighted SGs combined to obtain ...

System and methods for adaptive noise quantification in dynamic biosignal analysis

An adaptive noise quantification system and associated methods are disclosed for use in the dynamic biosignal analysis of a user. In at least one embodiment, the system includes a biosignal sensor positioned and configured for obtaining and transmitting data related to a select at least one vital of the user as a biosignal, and a motion sensor positioned and configured for obtaining and transmitting data related to a motion level of the user as a motion signal. A computing device is configured for receiving and processing the biosignal and motion signal.

Methods for continuous glucose monitoring

Electrochemical impedance spectroscopy (EIS) may be used in conjunction with continuous glucose monitoring (CGM) to enable identification of valid and reliable sensor data, as well implementation of Smart Calibration algorithms. Calibration of a glucose sensor may also be performed using a calibration factor based on the age of the sensor. Finally, a calibration interval for a glucose sensor may be determined.

Apparatus, systems and methods for predicting, screening and monitoring of encephalopathy / delirium

The disclosed apparatus, systems and methods relate to predicting, screening, and monitoring for delirium. Systems and methods may include receiving one or more signals from one or more sensing devices; processing the one or more signals to extract one or more features from the one or more signals; analyzing the one or more features to determine one or more values for each of the one or more features; comparing at least one of the one or more values or a measure based on at least one of the one or more values to a threshold; determining a presence, absence, or likelihood of the subsequent development of delirium for a patient based on the comparison; and outputting an indication of the presence, absence, or likelihood of the subsequent development of delirium for the patient.

Method and Apparatus for Monitoring Cardio-Pulmonary Health

... 11 (K Disclosed is a cardio-pulmonary health monitoring apparatus. The apparatus comprises a contactless motion sensor configured to generate one or more movement signals representing bodily movement of a patient during a monitoring session; a processor; and a memory storing program instructions configured to cause the processor to carry out a method of processing the one or more movement signals. The method comprises extracting one or more sleep disordered breathing features from the one or more movement signals, and predicting whether a clinical event is likely to occur during a predetermined prediction horizon based on the one or more sleep disordered breathing features. A29446532.0116 ...

SELECTION OF ENSEMBLE AVERAGING WEIGHTS FOR A PULSE OXIMETER BASED ON SIGNAL QUALITY METRICS

A method and a system for ensemble averaging signals in a pulse oximeter, including receiving first and second electromagnetic radiation signals from a blood perfused tissue portion corresponding to two different wavelengths of light, obtaining an assessment of the signal quality of the electromagnetic signals, selecting weights for an ensemble averager using the assessment of signal quality, and ensemble averaging the electromagnetic signals using the ensemble averager.

ECG MACHINE INCLUDING FILTER FOR FEATURE DETECTION

A system and method of filtering input data to remove power line interference is disclosed. The system and method estimates the statistics of the input signal and include determining a value (R) from the ratio of a peak amplitude (A peak) and a root-mean-square of the amplitudes of the interference harmonics (A rms), calculate a running histogram of the determined value (R) to determine a threshold value (TH R), comparing the determined value (R) to the determined threshold value (TH R) to make a decision about feature existence, and outputting a feature decision. The system and method include estimating the interference level to determine if interference is low level or high level. The system and method include estimating interference using the feature detection, amplitude and phase; and removing the estimated interference from the signal to result in a signal substantially free of power line interference.

QUANTIFYING AN EMBEDDED PPG SIGNAL TO NOISE RATIO DEFINITION TO EXPLOIT MEDIATION OF PPG SIGNAL QUALITY ON WEARABLE DEVICES

Wearable data acquisition devices including sensors for detecting physiological signals are used to detect and measure various parameters pertaining to the health of the wearer. Through the use of algorithms, the data detected and measured by said sensors are processed to make inferences used to monitor the health of the wearer. An signal to noise ratio (SNR) calculation is used as a component of the sensitivity analysis of an algorithm. For example, a sleep algorithm will select a block of data, the SNR calculation will be done, with the average quality of the signal as result. The value associated with said signal quality may then be subjected to sensitivity analysis, which will yield a sleep accuracy value which, in turn, is indicative of the minimum signal quality which is required.

USE OF ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY (EIS) IN CONTINUOUS GLUCOSE MONITORING

METHODS, SYSTEMS, AND DEVICES FOR SENSOR FUSION

A single, optimal, fused sensor glucose value may be calculated based on respective sensor glucose values of a plurality of redundant working electrodes (WEs) of a glucose sensor. Respective electrochemical impedance spectroscopy (EIS) procedures may be performed for each of the WEs to obtain values of membrane resistance (Rmem) for each WE. A noise value and a calibration factor (CF) value may be calculated for each WE, and respective fusion weights may be calculated for Rmem, noise, and CF for each WE. An overall fusion weight may then be calculated based on the WE' s Rmem fusion weight, noise fusion weight, and CF fusion weight, such that a single, optimal, fused sensor glucose value may be calculated based on the respective overall fusion weight and sensor glucose value of each of the plurality of redundant working electrodes.

MONITORING AND IDENTIFYING LABORATORY ANIMALS THROUGH UWB AND OTHER DIGITAL SENSORY SIGNATURES

A method and system for the continuous monitoring of animal physiology in laboratory animal cages through the use of miniaturized sensors located throughout the cage and in various fashions including the ability to identify each rodent's digital sensory signature through data fusion and artificial intelligence.

LONGITUDINAL ANALYSIS AND VISUALIZATION UNDER LIMITED ACCURACY SYSTEM

Processing logic makes a comparison between first image data and second image data of a dental arch and determines a plurality of spatial differences between a first representation of the dental arch in the first image data and a second representation of the dental arch in the second image data. The processing logic determines that a first spatial difference is attributable to scanner inaccuracy and that a second spatial difference is attributable to a clinical change to the dental arch. The processing logic generates a third representation of the dental arch that is a modified version of the second representation, wherein the first spatial difference is removed in the third representation, and wherein the third representation comprises a visual enhancement that accentuates the second spatial difference.

METHOD AND APPARATUS FOR TRANSDERMAL IN VIVO MEASUREMENT BY RAMAN SPECTROSCOPY

The use of a transdermal Raman spectrum to measure glucose or other substance concentration can give an inaccurate result if the Raman signals originate at a wrong skin depth. To predict whether a spectrum of Raman signals received transdermally in a confocal detector apparatus and having at least one component expected to have an intensity representing the concentration of glucose or another skin component at a point of origin of said Raman signals below the surface of the skin will accurately represent said concentration, peaks in the spectrum at 883/4cm-1 and 894cm-1 are measured to determine whether the Raman signals originate primarily within the stratum corneum so that the spectrum will be less likely to represent said concentration accurately or originate primarily below the stratum corneum so that the spectrum will be more likely to represent said concentration accurately.

ELECTROCARDIOGRAM NOISE REDUCTION

... includes an electrophysiologic (EP) catheter which has a lumen receiving an electrically conductive fluid delivered by a hydraulic line that is acted upon by a peristaltic pump advantageously avoids noise in intracardiac ECG signal recordings by using an electrical connection to short triboelectrical charge carried by the conductive fluid in the hydraulic line to an existing analog ground in the system. In one embodiment, the electrical connection includes an electrically conductive wire housed in the control handle and configured to provide electrical connection between the fluid and a pin on a printed circuit board housed in the control handle that is electrically connected to the analog ground. In another embodiment, the electrical connection shorts the electrically conductive fluid proximal of the control handle of the catheter.

SYSTEM AND METHODS FOR VIDEO-BASED MONITORING OF VITAL SIGNS

The present invention relates to the field of medical monitoring, and in particular non-contact, video-based monitoring of pulse rate, respiration rate, motion, and oxygen saturation. Systems and methods are described for capturing images of a patient, producing intensity signals from the images, filtering those signals to focus on a physiologic component, and measuring a vital sign from the filtered signals.

CALIBRATION OF GLUCOSE MONITORING SENSOR AND/OR INSULIN DELIVERY SYSTEM

Disclosed are methods, apparatuses, etc. for calibrating glucose monitoring sensors and/or insulin delivery systems. In certain example embodiments, blood glucose reference samples may be correlated with sensor measurements with regard to a delay associated with the sensor measurements. In certain other example embodiments, one or more parameters of a probability model may be estimated based on blood glucose reference sample-sensor measurement pairs. Based on such information, function(s) for estimating a blood-glucose concentration in a patient may be determined.

METHODS AND SYSTEMS FOR IMPROVING THE RELIABILITY OF ORTHOGONALLY REDUNDANT SENSORS

Methods and systems for sensor calibration and sensor glucose (SG) fusion are used advantageously to improve the accuracy and reliability of orthogonally redundant glucose sensor devices, which may include optical and electrochemical glucose sensors. Calibration for both sensors may be achieved via fixed-offset and/or dynamic regression methodologies, depending, e.g., on sensor stability and Isig-Ratio pair correlation. For SG fusion, respective integrity checks may be performed for SG values from the optical and electrochemical sensors, and the SG values calibrated if the integrity checks are passed. Integrity checks may include checking for sensitivity loss, noise, and drift. If the integrity checks are failed, in-line sensor mapping between the electrochemical and optical sensors may be performed prior to calibration. The electrochemical and optical SG values may be weighted (as a function of the respective sensor's overall reliability index (RI)) and the weighted SGs combined to obtain ...

METHODS AND DEVICES FOR ACCURATELY CLASSIFYING CARDIAC ACTIVITY

Methods, systems, and devices for signal analysis in an implanted cardiac monitoring and treatment device such as an implantable cardioverter defibrillator. In some examples, captured data including detected events is analyzed to identify likely overdetection of cardiac events. In some illustrative examples, when overdetection is identified, data may be modified to correct for overdetection, to reduce the impact of overdetection, or to ignore overdetected data. Several examples emphasize the use of morphology analysis using correlation to static templates and/or inter-event correlation analysis.

METHODS AND SYSTEMS FOR PROCESSING PHYSIOLOGICAL SIGNALS

A physiological monitoring system may determine physiological information, such as physiological rate information, and other information, such as noise information, from a physiological signal. The system may generate a difference signal based on the physiological signal and sort the difference signal to generate a sorted difference signal. The system may determine a value indicative of noise based on one or more data points identified from the sorted difference signal. The system may also condition physiological data to assist in the determination of the physiological information. The system may calculate differences based on the physiological data and modify the physiological data based on differences that exceed a threshold. The system may also apply a digital filter to physiological signal to assist in the determination of the physiological information. The filter may be adjustable, allowing selectivity in the characteristics of the digital filter between weighting the physiological ...

A SYSTEM AND METHOD TO DETECT SIGNIFICANT ARRHYTHMIC EVENTS THROUGH A PHOTOPLETHYSMOGRAM (PPG) AND ACCELEROMETER

A medical system (10) and method detect arrhythmi cevents. The medical system (10)includes at least one processor (28, 34, 50) programmed to perform the method. A photoplethysmogram (PPG) signal generated using a PPG probe (12)positioned on or within a patient (14) anda pulse signal generated using an accelerometer (38)positioned on or within the patient (14) received. Features from the PPG signal are extracted to PPG feature vectors, and features are extracted from the pulse signal to pulse feature vectors. The PPG feature vectors are correlated with the pulse feature vectors, and correlated PPG feature vectors and correlated pulse feature vectors are evaluated to detect arrhythmic events.

APPLICATION OF ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY IN SENSOR SYSTEMS, DEVICES, AND RELATED METHODS

A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the ElS-based diagnostics, fusion algorithms, and other processes based on measurement of ElS-based parameters.

SYSTEMS AND METHODS FOR PROVIDING SENSITIVE AND SPECIFIC ALARMS

Systems and methods for providing sensitive and specific alarms indicative of glycemic condition are provided herein. In an embodiment, a method of processing sensor data by a continuous analyte sensor includes: evaluating sensor data using a first function to determine whether a real time glucose value meets a first threshold; evaluating sensor data using a second function to determine whether a predicted glucose value meets a second threshold; activating a hypoglycemic indicator if either the first threshold is met or if the second threshold is predicted to be met; and providing an output based on the activated hypoglycemic indicator. The system (100) can include a continuous analyte sensor system (8), sensor electronics (12), a continuous analyte sensor (10), and other devices and/or sensors such as medicament delivery pump (2) and glucose meter (4) that can couple with one or more devices (14, 16, 18, and/or 20).

METHOD FOR MEASURING A PHYSIOLOGICAL PARAMETER, SUCH AS A BIOLOGICAL RHYTHM, ON THE BASIS OF AT LEAST TWO SENSORS, AND ASSOCIATED MEASUREMENT DEVICE

La présente invention concerne un procédé de mesure d'un paramètre physiologique tel qu'un rythme biologique à partir d'au moins deux capteurs ainsi qu'un dispositif de mesure associé et tel que le procédé comporte, selon l'invention, une étape de mesure du paramètre physiologique pour chaque capteur permettant de générer une série de mesures d'au moins deux valeurs, une étape d'évaluation du niveau de cohérence de chaque valeur de la série de mesures, une étape de sélection d'une valeur parmi l'ensemble des valeurs de la série en fonction d'une part de leur niveau de cohérence respectif et d'autre part d'une valeur dite de référence, afin de déterminer une nouvelle valeur de référence et une étape de stockage de la nouvelle valeur de référence.

OTOSCOPE

The present invention refers to an otoscope (10) comprising a handle portion (12) allowing a user to manipulate the otoscope (10) during its application; and a head portion (14) exhibiting a substantially tapering form extending along a longitudinal axis (A) of the head portion (14), wherein the head portion (14) has a proximal end (16) adjacent to the handle portion (12) and a smaller distal end (18) adapted to be introduced in an ear canal of a patient's outer ear. The otoscope (10) further comprises an electronic imaging unit positioned at the distal end (18) of the head portion (14), especially at a distal tip (35) of the head portion (14), the otoscope (10) further comprising a probe cover moving mechanism (65) configured to move at least a portion of an at least partially transparent probe cover (60) adapted to be put over the head portion (14), especially configured to move the probe cover (60) with respect to at least one optical axis (X; X1, X2) of the electronic imaging unit ( ...

Apparatus and method for determining an axial position of an electrode array for electric impedance tomography.

Eine Vorrichtung (1) zur Elektro-Impedanz-Tomographie (30) mit einer Elektrodenanordnung mit einer zueinander beabstandet angeordneten Vielzahl von Elektroden (33), einer Signaleinspeisungs-Einheit (51) und einer Signalerfassungs-Einheit (50), einer Berechnungs- und Steuerungseinheit (70) ist ausgestaltet, eine Situation mit einem axialen Versatz der Elektrodenanordnung an einem Brustkorb (34) eines menschlichen Lebewesens zu ermitteln und ein Steuersignal (79) bereitzustellen, welches die Situation mit axialem Versatz der Elektrodenanordnung indiziert. Die Berechnungs- und Steuerungseinheit (70) kann als zentrale Einheit oder eine Anordnung von verteilten Einheiten (cloud-computing) ausgebildet sein, um den axialen Versatz zu ermitteln und bereitzustellen.

Apparatus and method for determining a peripheral shape an electrode arrangement for electric impedance tomography.

Eine Vorrichtung (1) zur Elektro-Impedanz-Tomographie (30) mit einer Elektrodenanordnung mit einer zueinander beabstandet angeordneten Vielzahl von Elektroden (33), einer Signaleinspeisungs-Einheit (51) und einer Signalerfassungs-Einheit (50), einer Berechnungs- und Steuerungseinheit (70) ist ausgestaltet, eine aktuelle elliptische Umfangsform (20) der Elektrodenanordnung an einem Brustkorb (34) eines menschlichen Lebewesens zu ermitteln und ein Steuersignal (79) bereitzustellen, welches die elliptische Umfangsform (20) der Elektrodenanordnung indiziert. Die Berechnungs- und Steuerungseinheit (70) kann als eine zentrale Einheit oder als eine Anordnung von verteilten Einheiten (Cloud-Computing) ausgebildet sein, um die aktuelle elliptische Umfangsform (20) zu ermitteln und bereitzustellen.

Apparatus and method for determining an axial position of an electrode array for electric impedance tomography.

Eine Vorrichtung (1) zur Elektro-Impedanz-Tomographie (30) mit einer Elektrodenanordnung mit einer zueinander beabstandet angeordneten Vielzahl von Elektroden (33), einer Signaleinspeisungs-Einheit (51) und einer Signalerfassungs-Einheit (50), einer Berechnungs- und Steuerungseinheit (70) ist ausgestaltet, eine Situation mit einem axialen Versatz der Elektrodenanordnung an einem Brustkorb (34) eines menschlichen Lebewesens zu ermitteln und ein Steuersignal (79) bereitzustellen, welches die Situation mit axialem Versatz der Elektrodenanordnung indiziert. Die Berechnungs- und Steuerungseinheit (70) kann als zentrale Einheit oder eine Anordnung von verteilten Einheiten (Cloud-Computing) ausgebildet sein, um den axialen Versatz zu ermitteln und bereitzustellen.

Apparatus and method for determining a peripheral shape an electrode arrangement for electric impedance tomography.

Eine Vorrichtung (1) zur Elektro-Impedanz-Tomographie (30) mit einer Elektrodenanordnung mit einer zueinander beabstandet angeordneten Vielzahl von Elektroden (33), einer Signaleinspeisungs-Einheit (51) und einer Signalerfassungs-Einheit (50), einer Berechnungs- und Steuerungseinheit (70) ist ausgestaltet, eine aktuelle elliptische Umfangsform (20´) der Elektrodenanordnung an einem Brustkorb (34) eines menschlichen Lebewesens zu ermitteln und ein Steuersignal (79) bereitzustellen, welches die elliptische Umfangsform (20) der Elektrodenanordnung indiziert. Die Berechnungs- und Steuerungseinheit (70) kann als eine zentrale Einheit oder als eine Anordnung von verteilten Einheiten (cloud-computing) ausgebildet sein, um die aktuelle elliptische Umfangsform (20´) zu ermitteln und bereitzustellen.

METHOD FOR OPERATING A MOTOR VEHICLE

HEART RATE MEASURING METHOD AND APPARATUS, AND ELECTRONIC TERMINAL

ELECTROPHYSIOLOGICAL ANALYSIS SYSTEM FOR DETECTING LEAKAGE CURRENT

SYSTEM OF MEASUREMENT OF the Cardiac rhythm Of a USER

SYSTEM FOR REAL-TIME MEASUREMENT OF THE ACTIVITY OF COGNITIVE FUNCTION AND METHOD OF CALIBRATING SUCH A SYSTEM

신체 활동 모니터 및 데이터 수집 유닛

... 신체 활동 데이터 수집 유닛은 상기 신체 활동 데이터 수집 유닛의 사용자의 맥박수를 나타내는 출력을 생성하는 하나 이상의 적외선 센서와, 적어도 상기 사용자의 체온을 나타내는 출력을 생성하는 적어도 하나의 온도 센서와, 상기 사용자의 움직임을 나타내는 출력을 생성하는 적어도 하나의 가속도 센서를 포함한다. 신체 활동 데이터 수집 유닛은 상기 하나 이상의 적외선 센서, 상기 적어도 하나의 온도 센서, 및 상기 적어도 하나의 가속도 센서로부터의 출력에 의해 상기 신체 활동 데이터 수집 유닛의 사용자의 맥박수, 체온, 및 움직임 특징을 판단하고, 하나 이상의 상기 맥박수, 상기 체온, 또는 상기 사용자의 움직임 특징에 의해 상기 사용자의 운동 레벨을 판단하며, 상기 운동 레벨이 미리 결정된 문턱값을 초과하는 기간 동안 상기 운동 레벨을 나타내는 데이터를 메모리에 저장하는 마이크로 컨트롤러를 더 포함한다.

BIOSIGNAL MEASUREMENT APPARATUS AND BIOSIGNAL MEASUREMENT METHOD

Provided are a biosignal measurement apparatus and a method thereof. The biosignal measurement apparatus includes a sensor which detects a signal from at least two reference marks displayed on the surface of an object, and a biosignal measurement position detecting part which uses the signal from the at least two reference marks and outputs information on the biosignal measurement potion. The biosignal measurement apparatus uses information on the biosignal measurement position and measures a biosignal. So, the reliability of the biosignal can be improved. COPYRIGHT KIPO 2016 ...

휴대용 펄스 측정 디바이스

... 발명의 일측면에 따라, 휴대용 펄스 측정 디바이스가 제공된다. 디바이스는 인체 조직을 통해 방사 에너지를 방출하기 위한 발광 소스(104, 106) 및 인체 조직을 통한 전파 후에 상기 방사 에너지의 세기를 검출하고 상기 전파를 나타내는 입력 신호들을 제공하기 위한 광 검출기(100, 102)에서 선택된 적어도 3개의 요소들(100, 102, 104, 106)을 포함하며, 적어도 하나의 발광 소스(104, 106) 및 적어도 하나의 광 검출기(100, 102)를 포함하는, 조명 구성; 입력 신호들을 처리하는 것에 응답하여 펄스 레이트를 결정하도록 구성된 처리 수단을 포함한다. 조명 구성의 요소들은 조명 구성에 발광 소스들(104, 106)이 조명 구성에 광 검출기들(100, 102)에 관련하여 비대칭으로 배치되는 구성으로 휴대용 펄스 측정 디바이스 내 배열된다.

메타노풀러렌

... 본 개시내용은 신규한 메타노풀러렌 유도체, 이로부터 제조된 네거티브형 포토레지스트 조성물 및 이를 이용하는 방법에 관한 것이다. 상기 유도체, 이의 포토레지스트 조성물 및 상기 방법은, 예를 들어 자외방사선, 초극자외방사선, 극자외방사선, X-선 및 하전입자선을 이용하는 미세한 패턴 공정에 이상적이다. 네거티브 감광성 조성물이 또한 개시된다.

드론을 이용한 모니터링 장치 및 모니터링 장치의 동작 방법

... 일 실시예에 따른 모니터링 장치는 대상 생체의 장기 내에 위치하여 대상 생체의 제1 생체 신호를 측정하고 제1 생체 신호를 전송하는 제1 측정 장치, 대상 생체의 피부 조직 내에 위치하여 대상 생체의 제2 생체 신호를 측정하고, 제1 생체 신호를 수신하며, 제1 생체 신호 및 제2 생체 신호를 포함하는 생체 정보를 송신하는 제2 측정 장치, 대상 생체가 위치하는 영역으로 이동하고, 제2 측정 장치로부터 생체 신호를 수신하며, 생체 정보를 송신하는 드론, 및 드론으로부터 수신한 생체 정보에 기초하여 대상 생체의 상태를 분석 및 모니터링하는 분석 장치를 포함한다.

Device And Method To Activate Cell Structures By Means Of Electromagnetic Energy

HEART RATE AND PULSE MONITORING DEVICE

Methods, devices and systems for obtaining heart rate by obtaining apical and non-apical heart rate datum using first and second heart rate monitoring devices. The apical and non-apical heart rate data are input into a heart rate verification module (HRVM) that includes a number of programming instructions for effecting the invention. An apical heart rate measure and non-apical heart rate measure are calculated in the HRVM, and an acceptable heart rate range is generated using the apical heart rate measure. Whether the non-apical heart rate measure is a reliable measure of a true heart rate is identified by determining whether the non-apical heart rate measure falls within or outside the acceptable heart rate range. A split display screen of the HRVM displays the apical heart rate measure, non-apical heart rate measure, and information identifying whether the non-apical heart rate measure falls within or outside the acceptable heart rate range.

MULTIPLE WAVELENGTH SENSOR SUBSTRATE

A physiological sensor has emitters configured to transmit optical radiation having multiple wavelengths in response to corresponding drive currents. A thermal mass is disposed proximate the emitters so as to stabilize a bulk temperature for the emitters. A temperature sensor is thermally coupled to the thermal mass. The temperature sensor provides a temperature sensor output responsive to the bulk temperature so that the wavelengths are determinable as a function of the drive currents and the bulk temperature.

LOCAL SIGNAL-TO-NOISE PEAK DETECTION

Biometric sensor systems are provided for identifying fundamental heart rate harmonics within noisy sensor signals. The system calculates a local signal-to-noise ratio for one or more identified frequency bands received in a biometric signal. The identified frequency bands are ranked based upon the calculated local signal-to-noise ratio. The fundamental heart rate is identified based upon the ranking of the identified frequency bands.

Scanned laser vein contrast enhancer

The present invention is a Miniature Vein Enhancer that includes a Miniature Projection Head. The Miniature Projection Head may be operated in one of three modes, AFM, DBM, and RTM. The Miniature Projection Head of the present invention projects an image of the veins of a patient, which aids the practitioner in pinpointing a vein for an intravenous drip, blood test, and the like. The Miniature projection head may have a cavity for a power source or it may have a power source located in a body portion of the Miniature Vein Enhancer. The Miniature Vein Enhancer may be attached to one of several improved needle protectors, or the Miniature Vein Enhancer may be attached to a body similar to a flashlight for hand held use. The Miniature Vein Enhancer of the present invention may also be attached to a magnifying glass, a flat panel display, and the like.

Portable device with multiple integrated sensors for vital signs scanning

In one embodiment of the invention, a portable device with multiple integrated sensors for vital signs scanning and method of using said device is disclosed. The portable personal scanning device includes multiple sensors such as a plurality of ECG, thermometer, PPG, accelerometer, and microphone for determining a user's vital signs. The method includes concurrently scanning with one or more sensors, validating and enhancing the results of each sensor scan with other concurrent sensor scan and patient interaction models, processing the sensor scans separately or in combination to extract user's vital signs, validating the vital signs extracted by comparison to physiological models, and fusing the similar vital signs extracted from more than one process according to a determination of the measure of quality of the process that produced the vital sign.

Advanced electronic instrumentation for electrical impedance myography

Embodiments of devices and methods for evaluating tissue are disclosed. In one embodiment, a method for measuring a characteristic of a tissue may include passing a current through the tissue, measuring a signal corresponding to the voltage resulting from passing the current through the tissue, analyzing current passed through the tissue and resulting voltage to determine the electrical characteristics of the tissue; and analyzing the electrical characteristics of the tissue to determine a status of the tissue. Disposable sensors are disclosed.

Multiple wavelength sensor interconnect

A sensor interconnect assembly has a circuit substrate. An emitter portion of the substrate is adapted to mount emitters. A detector portion of the substrate is adapted to mount a detector. A cable portion of the substrate is adapted to connect a sensor cable. A first group of conductors are disposed on the substrate electrically interconnecting the emitter portion and the cable portion. A second group of conductors are disposed on the substrate electrically interconnecting the detector portion and the cable portion. A decoupling portion of the substrate disposed proximate the cable portion substantially mechanically isolating the cable portion from both the emitter portion and the detector portion so that sensor cable stiffness is not translated to the emitters or the detector.

FLOWOMETRY IN OPTICAL COHERENCE TOMOGRAPHY FOR ANALYTE LEVEL ESTIMATION

Optical coherence tomography (herein “OCT”) based analyte monitoring systems are disclosed. In one aspect, techniques are disclosed that can identify fluid flow in vivo (e.g., blood flow), which can act as a metric for gauging the extent of blood perfusion in tissue. For instance, if OCT is to be used to estimate the level of an analyte (e.g., glucose) in tissue, a measure of the extent of blood flow can potentially indicate the presence of an analyte correlating region, which would be suitable for analyte level estimation with OCT. Another aspect is related to systems and methods for scanning multiple regions. An optical beam is moved across the surface of the tissue in two distinct manners. The first can be a coarse scan, moving the beam to provide distinct scanning positions on the skin. The second can be a fine scan where the beam is applied for more detailed analysis.

IMPROVED SPHYGMOMANOMETER CAPABLE OF DISPLAYING THE QUALITY OF BLOOD PRESSURE READINGS

The present invention relates to an improved non-invasive sphygmomanometer which is able to calculate the quality of a blood pressure reading and display quality information to the user. More specifically the invention relates to a sphygmomanometer and the use of oscillometric readings to calculate the quality of the readings, and a quality indicator device for use with the same. The invention uses the identified relationship between the waveform quality from recorded oscillometric pulses and blood pressure (BP) measurement error.

SYSTEMS AND METHODS OF IDENTITY ANALYSIS OF ELECTROCARDIOGRAMS

Disclosed systems include an electrocardiogram sensor configured to sense electrocardiograms of a subject and a processing device operatively coupled to the electrocardiogram sensor. The processing device receives an electrocardiogram from the electrocardiogram sensor. The electrocardiogram is input into a machine learning model, the machine learning model to generate an output based on the received electrocardiogram. The processing device determines based on the electrocardiogram, that the output does not match an expected range of outputs for the target subject and generates an alert indicating a possible change in a status of the subject in response to the output not matching the expected range of outputs for the target subject.

Apparatus and methods for removing a large-signal voltage offset from a biomedical signal

Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.

Closed loop control system with safety parameters and methods

Methods, system and devices for monitoring a plurality of parameters associated with a closed loop control operation including continuously monitoring a physiological condition and automatic administration of a medication, detecting an adverse condition associated with the monitored physiological condition or the medication administration deviating from a predetermined safety level of the closed loop control operation, and initiating a non-zero pre-programmed medication delivery rate are provided.

MAGNETIC RESONANCE IMAGING APPARATUS

According to one embodiment, a magnetic resonance imaging apparatus includes processing circuitry. The processing circuitry collects magnetic resonance data in accordance with a pulse sequence. The processing circuitry determines image quality based on the magnetic resonance data. The processing circuitry selects a re-collection pulse sequence when it is determined that the image quality does not satisfy criteria, the re-collection pulse sequence having at least one of a type of sequence or an imaging condition differing from that of the pulse sequence.

MEDICAL DEVICE FOR SENSING CARDIAC FUNCTION

According to at least one aspect, a medical device is provided. The medical device includes at least one electrode to sense an electrocardiogram (ECG) signal of a patient and a controller coupled to the at least one electrode. The controller may be configured to generate a first ECG template based on a first ECG signal of the patient, generate a second ECG template based on a second ECG signal of the patient, and determine whether the patient is experiencing a cardiac event based on the ECG signal of the patient and an identified one of the first ECG template and the second ECG template.

ELECTROCARDIOGRAPHY MONITORING SYSTEM AND METHOD

Systems and methods for electrocardiography monitoring use multiple capacitive sensors in order to determine reliable measurements of electrophysiological information of a patient. Relative coupling strength and/or reliability is used to select dynamically which sensors to use in order to determine, in particular, an electrocardiogram of the patient.

Implantable therapeutic device control system

A control system for an implantable cardiac therapy device, the device defining a plurality of sensing vectors including at least one impedance sensing vector and operating under a set of a plurality of variable operating parameters that define conditions for delivery of therapy and wherein the control system evaluates signal quality from the at least one impedance sensing vector and, if the quality is sufficient to discern valvular events, the control system adjusts the set of operating parameters to dynamically improve cardiac performance, including synchrony with valvular events, and if the quality is insufficient to discern valvular events, but sufficient to discern peaks, the control system adjusts the set of operating parameters to dynamically improve cardiac performance independent of valvular events, and if the quality is insufficient to discern peaks, the control system adjusts the set of operating parameters to induce cardiac performance towards a defined performance goal.

DETERMINATION OF BLOOD PRESSURE MEASUREMENT CONFIDENCE USING VARIABLE MONITOR INACCURACY

Apparatuses and methods for displaying a blood pressure monitoring instrument reading along with inaccuracy values that vary over apparatus life and according to current operating conditions are disclosed. These inaccuracy values account for variability under different operating environments, over time and number of device measurement cycles, and across the range of possible instrument reading conditions. Determination of inaccuracy values may be based both on apparatus history and measurement under the current operating condition. Methods can further include informing a user of confidence in the instrument's current measurements based on the instrument's measurements and inaccuracy.

POWER MANAGEMENT FOR WEARABLE DEVICES

A method, system, apparatus, and/or device for adjusting a power consumption level of a device. The method, system, apparatus, and/or device may include: a first sensor interface, a second sensor interface, and a processing device coupled to the first sensor interface and the second sensor interface. The processing device may: measure a first physiological measurement via the first sensor interface within a first period of time; measure a second physiological measurement via the second sensor interface within the first period of time; adjust a power consumption level of the apparatus in view of at least one of the first physiological measurement or the second physiological measurement; measure the physiological measurement via the first sensor interface at the adjusted power consumption level within a second period of time; and measure a second physiological measurement via the second sensor interface at the adjusted power consumption level within the second period of time.

Determination and application of glucose sensor reliability indicator and/or metric

Disclosed are a system and method for determining a metric and/or indicator of a reliability of a blood glucose sensor in providing glucose measurements. In one aspect, the metric and/or indicator may be computed based, at least in part, on an observed trend associated with signals generated by the blood glucose sensor.

System and method for dynamic data management in a wireless network

A node is configured for transmitting a data packet over a wireless network according to a differentiated services control parameter. The node includes a controller configured to provide individualized control of the differentiated services code parameter and also to provide individualized control over a payload in the data packet. The controller is also configured to receive data to be transmitted over the wireless network, assign a priority level to the data, and adjust the differentiated services control parameter setting for the node based on the priority level. The controller is also configured to determine a signal quality indicator for the wireless network, and to adjust the amount of the data included in the payload based on the signal quality indicator.

Physiology Monitoring and Alerting System and Process

A system for monitoring physiology, having: a RADAR transmitter and a RADAR receiver; a state estimation module configured to process a returned RADAR signal to detect a presence of motion and set a motion state upon said presence of motion, said state estimation module configured to detect a presence of one or more physiological parameters including heartbeat and respiration, and said state estimation module configured to assign a still state or a concern state based on said presence of physiological parameters; a rate estimation module configured to estimate one or more estimated physiological rates including an estimated respiration rate and an estimated heart rate; and an alerting module configured to provide an alert if an alert value exceeds an alert value threshold, wherein the alert value is derived from at least one of the motion state, concern state, still state and the estimated physiological rates.

Systems and methods for latency and measurement uncertainty management in stimulus-response tests

Disclosed are systems and methods for managing testing unit latency and measurement uncertainty in computer-based stimulus-response tests. An estimated latency L E and an associated measurement uncertainty are determined as characteristics of a particular testing unit. L E is used as offset for all measurements taken on the testing unit, and results treated subject to the characteristic measurement uncertainty when determining test-taker performance. Estimated actual response times RT E are processed subject to a confidence value determined from the uncertainty. Uncertainty propagation determines test metrics involving a plurality of estimated actual response times RT E , where cumulative uncertainty is reported as a confidence rating in the metric. Overall test results (e.g., pass vs. fail) based on one or more metrics are also reported according to a confidence rating associated with the cumulative uncertainty propagated through the relevant metrics. Various calibration techniques are disclosed for determining the latency estimate L E and associated uncertainty values.

Vessel pulse wave measurement system conducting vessel pulse wave measurement by obtaining pulsation waveform of blood vessel

A vessel pulse wave measurement system performs vessel pulse wave measurement using an optical probe circuit provided with an optical probe including a light emitting element and a light receiving element, a drive circuit, and a detection circuit. A measurement device directly and synchronously feeds back an electrical signal from the optical probe to the drive circuit as a drive signal to generate a self-oscillation signal from the detection circuit, and measures the self-oscillation signal as a vessel pulse wave signal. A controller controls an operating point of at least one of the detection circuit and the drive circuit such that the self-oscillation signal substantially reaches a maximum level thereof.

Method and system for activity/rest identification

Disclosed embodiments include a method for automatic identification of activity and rest periods based on an actigraphy signal. According to an embodiment, the method comprises (a) applying one or more filters to the actigraphy signal to generate a filtered actigraphy signal, and (b) comparing the filtered actigraphy signal against an adaptive threshold to generate an output signal corresponding to the activity and rest periods. The method can be implemented as part of a medical apparatus or medical system for automatic activity/rest identification from actigraphy signals.

Method for classification of eye closures

The present invention generally relates to a method for improving the reliability of a portion of physiological data from an image sensor monitoring an operator positioned in an operator compartment of a vehicle. An embodiment of the method includes receiving, from the image sensor, physiological data including information relating to at least one of eye, face, head, arms and body motion of the operator, identifying an indication of at least an eyelid closure, eye movement or head movement of the operator based on the physiological data; comparing at least one of the physiological data and a lighting condition within the operator compartment with a set of rules for a current operator status; and classifying the type of eyelid closure, eye movement and/or head movement by correlating the identified eyelid closure, eye movement and/or head movement and a result of the comparison.

Fault-tolerant sensing in an implantable medical device

A system includes a memory and a processing module. The memory includes a primary sensing vector and N alternate sensing vectors. The processing module determines a ranking value for each of the N alternate sensing vectors. Each ranking value is indicative of the integrity of a cardiac electrical signal acquired via the corresponding alternate sensing vector. The processing module senses cardiac events using the primary sensing vector, detects a reduction in the integrity of a cardiac electrical signal acquired via the primary sensing vector, and selects one of the N alternate sensing vectors in response to detecting a reduction in the integrity of the cardiac electrical signal acquired via the primary sensing vector. The selection is based on the ranking value associated with the one of the N alternate sensing vectors. The processing module then senses cardiac events using the selected one of the N alternate sensing vectors.

Intravascular sensing method and system

Methods and systems for calculating a corrected Fractional Flow Reserve. Methods include delivering a pressure sensing device including a pressure sensor to a location in an artery having a stenosis, positioning the pressure sensor distal to the stenosis, measuring the distal pressure, measuring the proximal pressure, and calculating a corrected Fractional Flow Reserve using the measured proximal and distal pressures and applying a correction factor or correction equation. The correction factor or correction equation corrects for changes in the measured distal pressure caused by a presence of the pressure sensing device. A data set of correction factors or correction equations may be stored in a memory component of the system. The corrected Fractional Flow reserve may approximate the Fractional Flow Reserve that would be obtained if a different sized device was used to measure the distal pressure, such as a pressure sensing guidewire having a 0.014 inch outer diameter.

Multiple wavelength sensor emitters

A physiological sensor has light emitting sources, each activated by addressing at least one row and at least one column of an electrical grid. The light emitting sources are capable of transmitting light of multiple wavelengths and a detector is responsive to the transmitted light after attenuation by body tissue.

Active implantable medical device comprising means for the diagnosis of heart failure

Methods, devices, and processor-readable storage media are provided for the diagnosis of heart failure. A method in this context includes collecting, using an implantable device, reference episodes, the reference episodes comprising, at least one of: electrical activity signals of a myocardium; myocardium hemodynamic activity signals, or indicators reflecting variation of physical parameters, variation of activity, and variation of hemodynamic phases between phases of effort and phases of recovery; generating an in-suspicion model-cycle and an off-suspicion model-cycle based on the reference episodes; and determining whether to generate an early heart failure alert, based on a difference between the in-suspicion model-cycle and the off-suspicion model-cycle.

MONITORING SYSTEM

Apparatus for performing impedance measurements on a subject. The apparatus includes a first processing system for determining an impedance measurement procedure and determining instructions corresponding to the measurement procedure. A second processing system is provided for receiving the instructions, using the instructions to generate control signals, with the control signals being used to apply one or more signals to the subject. The second processing system then receives first data indicative of the one or more signals applied to the subject, second data indicative of one or more signals measured across the subject and performs at least preliminary processing of the first and second data to thereby allow impedance values to be determined. 1) A method of performing impedance measurements on a subject , the method including , in a processing system:a) determining an encoded value associated with at least one electrode lead; and,b) causing at least one impedance measurement to be performed using the encoded value.2) A method according to claim 1 , wherein the encoded value is used for calibration.3) A method according to claim 1 , wherein the encoded value is determined from a resistance value.4) A method according to claim 1 , wherein the encoded value is indicative of an identity of the lead.5) A method according to claim 1 , wherein the method includes claim 1 , in the processing system claim 1 , controlling the current applied to the subject using the encoded value.6) A method according to claim 1 , wherein the encoded value is a lead identifier claim 1 , and wherein the method includes claim 1 , in the processing system:a) determining, using the lead identifier, an impedance measurement procedure; and,b) causing the determined impedance measurement procedure to be performed.7) A method according to claim 6 , wherein the method includes claim 6 , in the processing system:a) comparing the determined identifier to one or more predetermined identities; and,b) ...

METHODS AND DEVICES FOR ACQUIRING ELECTRODERMAL ACTIVITY

Handheld devices using an array of stainless steel electrodes located on an edge and/or back of the handheld devices for acquiring electrodermal activity are provided. The stainless steel electrode array may allow for the skin conductance level (SCL) or skin conductance response (SCR) on an individual to be measured and collected. The skin conductance signal may be related to sympathetic nervous system activity which is a major component of human emotion, known as arousal, or emotional intensity such as anxiety, stress, fear, or excited, etc. 1. A device , comprising:an array of stainless steel electrodes;a polarity switching module coupled to the array of stainless steel electrodes for switching polarity of electrodes in the array of stainless steel electrodes;a memory device; and determine a number of adjacent electrode pairs in the array of stainless steel electrodes contacted to scale a skin conductance response threshold;', 'fuse all negative electrodes together and all positive electrodes together in the array of stainless steel electrodes upon activation of the electrodes in the array of stainless steel electrodes; and', 'measure a single overall skin conductance response to capture a total electrode activity measurement., 'at least one processor coupled to the array of stainless steel electrodes and the memory device, the at least one processor configured to2. The device of claim 1 , further comprising a force sensor array coupled to each electrode pair in the array of stainless steel electrodes for detecting grip force.3. The device of claim 2 , wherein the at least one processor is further configured to:invalidate captured electrodermal activity data if changing grip force or if the grip force exceeds a grip force threshold.4. The device of claim 1 , wherein the at least one processor is further configured to:reverse the current flow direction through the one or more electrode pairs in the array of stainless steel electrodes as each electrode pair is ...

Pathlength Enhancement of Optical Measurement of Physiological Blood Parameters

Systems and methods for measuring a physiological parameter of tissue in a patient are provided herein. In a first example, a method of measuring a physiological parameter of blood in a patient is provided. The method includes emitting at least two optical signals for propagation through tissue of the patient, detecting the optical signals after propagation, identifying propagation pathlengths of the optical signals, and identifying detected intensities of the optical signals. The method also includes processing at least the propagation pathlengths to scale the detected intensities for determination of a value of the physiological parameter.

Medical device failure detection and warning system

A failure detection and warning system for monitoring a medical device wherein the system includes means structured to passively or actively detect faults occurring in the medical device being monitored, and wherein the fault includes an unprogrammed and/or undesired shut off of the medical device being monitored or an unprogrammed and/or undesired shut-off of the output of the medical device being monitored by the system.

Apparatus and Method for Measuring Physiological Signal Quality

An apparatus and method for determining a signal quality of an input signal representing a repetitious phenomena derived from at least one sensor connected to a patient is provided. A detector receives the input signal and determines data representing the repetitious phenomena from the input signal for use in determining at least one patient parameter. A measurement processor is electrically coupled to the detector that determines a first signal quality value by identifying at least one feature of the repetitious phenomena data and compares the at least one feature of a first set of the determined repetitious phenomena data with a second set of the determined repetitious phenomena data to determine a feature variability value and using the feature variability value to determine a stability value representative of the quality of the input signal. 1. An apparatus for determining a signal quality of an input signal representing a repetitious phenomena derived from at least one sensor connected to a patient comprising:a detector that receives the input signal and determines data representing the repetitious phenomena from the input signal for use in determining at least one patient parameter;a measurement processor electrically coupled to the detector that determines a first signal quality value by identifying at least one feature of the repetitious phenomena data and compares the at least one feature of a first set of the determined repetitious phenomena data with the at least one feature of a second set of the determined repetitious phenomena data to determine a feature variability value and using the feature variability value to determine a stability value representative of the quality of the input signal.2. The apparatus as recited in claim 1 , whereinsaid measurement processor automatically compares the determined stability value with a threshold value to determine the quality of the input signal.3. The apparatus as recited in claim 2 , whereinsaid measurement ...

APPARATUS AND METHOD FOR DETECTING MISALIGNMENT BETWEEN IMPLANTABLE BIO SENSOR AND BIO-SIGNAL RECEIVING MODULE

A method for detecting in a bio sensor misalignment between the bio sensor and a bio signal receiving module is provided. The method includes receiving, by the bio sensor, a light signal from the bio signal receiving module, determining, by the bio sensor, whether the light signal is received in a misalignment detection section, determining, by the bio sensor, that the bio sensor and the bio signal receiving module are misaligned if the light signal is received in the misalignment detection section, generating a feedback signal that comprises information to indicate misalignment between the bio sensor and the bio signal receiving module, and transmitting, by the bio sensor, the feedback signal to the bio signal receiving module. 1. A method for detecting , in a bio sensor , misalignment between the bio sensor and a bio signal receiving module , the method comprising:receiving, by the bio sensor, a light signal from the bio signal receiving module;determining, by the bio sensor, whether the light signal is received in a misalignment detection section;determining, by the bio sensor, that the bio sensor and the bio signal receiving module are misaligned if the light signal is received in the misalignment detection section;generating a feedback signal that comprises information to indicate misalignment between the bio sensor and the bio signal receiving module; andtransmitting, by the bio sensor, the feedback signal to the bio signal receiving module.2. The method of claim 1 , wherein the determining that the bio sensor and the bio signal receiving module are misaligned comprises determining a direction in which the bio signal receiving module is deviated from the bio sensor claim 1 , andwherein the feedback signal further comprises information to indicate the direction in which the bio signal receiving module is deviated from the bio sensor.3. The method of claim 2 , wherein the determining as to which direction the bio signal receiving module is deviated from the bio ...

CONSISTENT SIGNAL SELECTION BY SIGNAL SEGMENT SELECTION TECHNIQUES

According to embodiments, techniques for selecting a consistent part of a signal, including a photoplethysmograph (PPG) signal, are disclosed. A pulse oximetry system including a sensor or probe may be used to obtain a PPG signal from a subject. Signal peaks may be identified in the PPG signal. Characteristics of the signal peaks, including the amplitude levels of the signal peaks and/or the time-distance between the signal peaks may be used to determine if the PPG signal is consistent. In an embodiment, signal peaks are processed based on a consistency metric, and the processed signal peaks are compared to the consistency metric to determine if the PPG signal is consistent. If the PPG signal is determined to be consistent, the PPG signal may be further analyzed to determine an underlying signal parameter, including, for example, a patient respiration rate. If the PPG signal is determined to be inconsistent, the inconsistent portion of the signal may be removed from the overall signal or otherwise transformed. 1. A method for processing a physiological signal , comprising:obtaining a photoplethysmograph (PPG) signal from a sensor;selecting a current portion of the PPG signal for analysis;identifying a plurality of consecutive signal peaks in the current portion of the PPG signal;processing the plurality of consecutive signal peaks;comparing the processed plurality of consecutive signal peaks, signal troughs of the plurality of consecutive peaks, or interpeak distances of the plurality of consecutive signal peaks to determine if the current portion of the PPG signal is consistent;responsive to determining that the current portion of the PPG signal comprising a plurality of consecutive peaks is consistent and comprises a target number of consecutive peaks, determining one or more parameters based at least in part on the current portion of the PPG signal; andresponsive to determining that the current portion of the PPG signal is not consistent, selecting a next portion ...

HEART RATE MONITOR

A signal processing apparatus for determining a heart rate includes a plurality of sensors configured to detect changes in blood properties in a user's skin and a heart rate Kalman filter configured to compute a heart rate on the basis of signals obtained from the plurality of sensors. A method of computing a heart rate using the apparatus includes detecting changes in blood properties with a plurality of sensors, and computing with a heart rate Kalman filter the heart rate on the basis of signals obtained from the plurality of sensors. 1. A signal processing apparatus to determine a heart rate comprising:a plurality of sensors configured to detect changes in blood properties in a user's skin; anda heart rate Kalman filter configured to compute a heart rate on the basis of signals obtained from the plurality of sensors;a communication link between the sensors and the heart rate Kalman filter to transmit the signals; anda housing to contain at least the plurality of sensors to maintain them in proximity to the user's skin.2. The apparatus of claim 1 , wherein the plurality of sensors comprise:an optical sensor comprising a plurality of light emitting devices and at least one photodetector, wherein the photodetector is configured to detect optical signals from the light emitting devices and ambient light; andan accelerometer configured to detect motion adding a noise signal to the optical signals.3. The apparatus of claim 2 , further comprising a driver to control a periodic emission level and timing of light output from the light emitting devices and a period of off state of the light emitting devices.4. The apparatus of claim 3 , further comprising a signal quality estimator to determine the emission level of the light emitting devices on the basis of the detected optical signals.5. The apparatus of claim 4 , wherein a one or more of a plurality of filters is configured to filter noise outside specified frequency bands from the optical signals claim 4 , and wherein ...

VITAL SIGN MEASUREMENT APPARATUS

A vital sign measurement apparatus including: an input operation section; a first measurement section capable of measuring first vital signs; first and second operating systems; a first arithmetic processing section that runs on the first operating system and that arithmetically processes the first vital signs on the basis of an input signal from the input operation section, thereby generating a first arithmetically processed signal; a second arithmetic processing section that runs on the second operating system, that is communicable with the first arithmetic processing section, and that generates a second arithmetically processed signal on the basis of the input signal from the input operation section by use of the first arithmetically processed signal transmitted from the first arithmetic processing section; and an output control section that can receive the first and second arithmetically processed signals and that outputs at least one of the received arithmetically processed signals. 1. A vital sign measurement apparatus comprising:an input operation section that enables an operator to perform input operation;a first measurement section capable of measuring first vital signs;a first operating system;a second operating system;a first arithmetic processing section that runs on the first operating system and that arithmetically processes the first vital signs measured by the first measurement section on the basis of an input signal from the input operation section, thereby generating a first arithmetically processed signal;a second arithmetic processing section that runs on the second operating system, that is communicable with the first arithmetic processing section, and that generates a second arithmetically processed signal on the basis of the input signal from the input operation section by use of the first arithmetically processed signal transmitted from the first arithmetic processing section; andan output control section that can receive the first ...

ADAPTIVE CALIBRATION SYSTEM FOR SPECTROPHOTOMETRIC MEASUREMENTS

This disclosure describes, among other features, systems and methods for customizing calibration curves, parameter algorithms, and the like to individual users. An initial calibration curve generated based on a population can be used as a starting point in an algorithm for measuring a physiological parameter such as glucose. The measurement algorithm can determine one or more initial measurement values for a user based on the initial calibration curve. In certain embodiments, one or more alternative measurements, such as invasive or minimally invasive measurements, can periodically or sporadically be input into the measurement algorithm. The algorithm can use the alternative measurements to adapt the calibration curve to the individual. As a result, measurements for the individual can more accurately reflect the individual's actual parameter values. 1. A method of determining whether to recommend an alternative measurement of a physiological parameter , the method comprising:obtaining a noninvasive measurement of a physiological parameter using an optical sensor;receiving an alternative measurement of the physiological parameter, the alternative measurement being generated by an alternative sensor;analyzing the noninvasive and alternative measurements by a processor to determine whether a condition has been met; andin response to the condition being met, outputting an indication that a new measurement should be obtained from the alternative sensor.2. The method of claim 1 , wherein analyzing the noninvasive and alternative measurements to determine whether a condition has been met comprises determining whether a difference between the noninvasive and alternative measurements exceeds a threshold.3. The method of claim 1 , wherein analyzing the noninvasive and alternative measurements to determine whether a condition has been met comprises determining a predetermined amount of time has passed.4. The method of claim 1 , wherein the indication comprises an alarm.5. The ...

ELECTROCARDIOGRAPHIC MONITORING SYSTEM AND METHOD

Disclosed is a method for obtaining a standard 12-lead electrocardiogram and a rhythm strip, comprising: a) capturing, by a personal ECG device, information related to the electrical activity of a user's heart as acquired from multiple skin monitoring electrodes positioned on the body of said user in a standard 12 lead anatomical manner; b) generating ECG data, by said personal ECG device, for obtaining said standard 12-lead electrocardiogram and said rhythm strip, wherein said generated ECG data represent the electrical activity of the heart of said user as acquired by said skin electrodes; and c) transferring said ECG data via a short range data communication wireless protocol to a paired mobile device, adapted to communicate with a remote data center for retransmitting said transferred ECG data to said remote data center; and processing said forwarded ECG data and creating a 12 lead ECG and Rhythm strip report at said remote data center. 1. A method for obtaining a standard 12-lead electrocardiogram and a rhythm strip , comprising:a. capturing, by a personal ECG device, information related to the electrical activity of a user's heart as acquired from at least 9 skin monitoring electrodes positioned on the body of said user in a standard 12 lead anatomical manner in accordance with Einthoven, Goldberger and Wilson, wherein said standard 12 lead anatomical manner is obtained by deploying said electrodes along a belt connected with said ECG device and on the rear side of said ECG device, wherein at least some of said skin electrodes are precordial electrodes that are located on the inside of said belt and are positioned on the chest of said user, 2 electrodes are belt mounted limb electrodes located on the outside of said belt to acquire electrical signals of the left arm (LA electrode) and the right arm (RA electrode), and 1 flying electrode (LL electrode) to acquire the electrical signals of the left leg of said user;b. generating ECG data, by said personal ECG ...

PULSE OXIMETER PROBE-OFF DETECTOR

A processor provides signal quality based limits to a signal strength operating region of a pulse oximeter. These limits are superimposed on the typical gain dependent signal strength limits. If a sensor signal appears physiologically generated, the pulse oximeter is allowed to operate with minimal signal strength, maximizing low perfusion performance. If a sensor signal is potentially due to a signal induced by a dislodged sensor, signal strength requirements are raised. Thus, signal quality limitations enhance probe off detection without significantly impacting low perfusion performance. One signal quality measure used is pulse rate density, which defines the percentage of time physiologically acceptable pulses are occurring. If the detected signal contains a significant percentage of unacceptable pulses, the minimum required signal strength is raised proportionately. Another signal quality measure used in conjunction with pulse rate density is energy ratio, computed as the percentage of total energy contained in the pulse rate fundamental and associated harmonics. 1. In a patient monitor configured to obtain signals responsive to physiological parameters of a monitored patient , a detector for determining when a physiological sensor may not be properly attached to said monitored patient with respect to a measurement site , the detector comprising:a limit selector configured to output a signal strength limit in response to a sensitivity mode; andlogic configured to indicate that a sensor not properly attached condition exists based on a comparison of a signal strength of one or more signals indicative of one or more physiological parameters and the signal strength limit.2. The detector of claim 1 , wherein the signal strength is based upon a ratio of a peak-to-peak AC signal to a DC signal.3. The detector of claim 2 , wherein the signal strength limit is about 0.05.4. The detector of claim 2 , wherein the signal strength limit is about 0.25.5. The detector of ...

DEVICE, METHOD AND COMPUTER PROGRAM PRODUCT FOR CONTINUOUS MONITORING OF VITAL SIGNS

A wearable device for continuous health monitoring, the device comprising: a band for conforming to a first body part of a subject; an imaging unit, the imaging unit being connected in the band, wherein the imaging unit is configured to acquire a sequence of images from the subject's body, wherein the device is operable in a contact mode and in a non-contact mode, i. wherein in the contact mode the imaging unit is in substantial close proximity to the first body part of the subject so as to acquire the sequence of images of an area of the first body part; wherein in the non-contact mode the imaging unit is in a remote position to acquire the sequence of images of a second body part of the subject; a controller unit configured to derive a PPG signal from the acquired sequence of images according to a first process when the device is in the contact mode and according to a second process when the device is in the non-contact mode, the PPG signal being indicative of the health of the subject; wherein the controller unit, during operation of the wearable device, is configured to check at least one pre-determined condition in order to determine if the PPG signal is to be derived according to the first process or the second process. 1. A wearable device for continuous health monitoring , the device comprising:a. a band for conforming to a first body part of a subject; i. wherein in the contact mode the imaging unit is in substantial close proximity to the first body part of the subject so as to acquire the sequence of images of an area of the first body part;', 'ii. wherein in the non-contact mode the imaging unit is in a remote position to acquire the sequence of images of a second body part of the subject;, "b. an imaging unit, the imaging unit being connected in the band, wherein the imaging unit is configured to acquire a sequence of images from the subject's body, wherein the device is operable in a contact mode and in a non-contact mode,"}c. a controller unit ...

CONTACTLESS ELECTRIC CARDIOGRAM SYSTEM

A system for providing a standard electrocardiogram (ECG) signal for a human body using contactless ECG sensors for outputting to exiting medical equipment or for storage or viewing on a remote device. The system comprises a digital processing module (DPM) adapted to connect to an array of contactless ECG sensors provided in a fabric or the like. A selection mechanism is embedded into the DPM which allows the DPM to identify body parts using the ECG signals of the different ECG sensors and select for each body part the best sensor lead. The DPM may then produce the standard ECG signal using the selected ECG signals for the different body parts detected. The system is adapted to continuously re-examine the selection to ensure that the best leads are selected for a given body part following a movement of the body part, thereby, allowing for continuous and un-interrupted ECG monitoring of the patient. 2. The device of claim 1 , wherein the processor is further adapted to perform the steps of:a. identifying a group of contactless ECG sensors that are in close proximity of the human body;b. dividing the identified group of contactless ECG sensors into sub-groups and associating each sub-group to a body part; andc. from each sub-group, selecting the contactless ECG sensor providing the highest signal quality.3. The device of claim 2 , wherein the processor identifies the contactless ECG sensors that are located in close proximity to the human body by measuring an impedance between each contactless ECG sensor and the human body.4. The device of claim 1 , wherein the processor is adapted to select another contactless ECG sensor for a given body part following a movement of the human body with respect to the array of contactless ECG sensors.5. The device of claim 4 , wherein the processor is adapted to continuously monitor a current signal quality of the selected contactless ECG sensor associated with each body part to select the other contactless ECG sensor when the current ...

Operation-verifying wearable vapor sensor

A system to measure sweat vapor may include a skin contact sensor, a sweat vapor sensor, and a processor. The skin contact sensor may be configured to measure one or more aspects indicative of whether the measuring device is in contact with skin of a user of the measuring device. The sweat vapor sensor may be configured to measure one or more properties of sweat vapor of the user; and the processor may be communicatively coupled to the skin contact sensor and the sweat vapor sensor. The processor may be configured to confirm operation of the measuring device based on the one or more aspects measured by the skin contact sensor, and the sweat vapor sensor receiving the sweat vapor.

DEVICE AND METHOD FOR CLASSIFYING THE ACTIVITY AND/OR COUNTING STEPS OF A USER

Device and method for classifying the activity and/or counting steps of a user. A method for classifying the activity of a user can comprise measuring accelerometer data for a plurality of axes; identifying a most active one of the plurality of axes based on the accelerometer data; and classifying the activity of the user based on a signal amplitude of the accelerometer data for the most active axis and one or more threshold values. 1. A device for counting the number of steps taken by a user wearing the device , the device comprising:an accelerometer for measuring accelerometer data for at least one axis; and apply a derivative operator to the accelerometer data in successive processing windows;', 'count peaks in the derivative of the accelerometer data in each processing window; and', 'eliminate over counted peaks based on time difference between a first peak in a current window and a last peak in a preceding processing window., 'a processor configured to2. The device as claimed in claim 1 , wherein the processor is configured to count the peaks based on a first threshold value if the current processing window is a first processing window after transiting from a light activity state to a moderate or a heavy activity state.3. The device as claimed in claim 1 , wherein the processor is further configured to update an adaptive threshold for the next window.4. The device as claimed in claim 3 , wherein the adaptive threshold for the next window is based on the difference in signal amplitude for a last successive peak and valley pair in the current processing window.5. The device as claimed in claim 4 , wherein the adaptive threshold for the next window is between about >0 to 50% of the difference in signal amplitude for the last successive peak and valley pair in the current processing window.6. The device as claimed in claim 1 , wherein the processor is configured to eliminate peaks from the peak count in the current window if the time difference between the first ...

MONITORING DEVICE FOR MONITORING OF VITAL SIGNS

A monitoring device for monitoring of vital signs of a living organism comprises at least two electrode pins for receiving an electrical activity of the living organism and an optical sensor for sensing a pulse of the living organism, wherein the monitoring device has a compact form and the at least two electrode pins and the optical sensor are integrated in the monitoring device. 1. A monitoring device for monitoring of vital signs of a living organism , wherein the monitoring device comprises:at least two electrode pins for receiving an electrical activity of the living organism; andan optical sensor for sensing a pulse of the living organism,wherein the monitoring device has a compact form and the at least two electrode pins and the optical sensor are integrated in the monitoring device.2. The monitoring device according to claim 1 , wherein the monitoring device is configured to determine an Electrocardiogram (ECG) and/or an Electromyogram (EMG) by analyzing the electrical activity claim 1 , wherein the electrical activity comprises at least an ECG signal claim 1 , at least an EMG signal claim 1 , or both.3. The monitoring device according to claim 1 , wherein the optical sensor is placed geometrically between the at least two electrode pins or wherein the monitoring device comprises at least one additional optical sensor.4. The monitoring device according to claim 1 , wherein the monitoring device has a form of a rectangular cuboid having maximum dimensions of 10 cm×6 cm×3 cm.5. The monitoring device according to claim 1 , wherein the at least two electrode pins are located on one side of the monitoring device and the optical sensor is located on an opposite side of the monitoring device claim 1 , wherein the at least two electrode pins are configured to be connected to a carrying means.6. The monitoring device according to claim 1 , wherein the monitoring device comprises at least one of: an accelerometer claim 1 , a temperature sensor claim 1 , a microphone ...

PHYSIOLOGICAL MONITORING DEVICES AND PHYSIOLOGICAL MONITORING METHOD

A physiological monitoring device is provided. The physiological monitoring device includes a physiological sensor, a quality estimator, and a feature extractor. The physiological sensor is configured to sense a physiological feature to generate a bio-signal. The quality estimator estimates quality of the bio-signal. The feature extractor receives the bio-signal and performs a predetermined operation to the bio-signal to obtain feature data. The amount of computation induced by the predetermined operation tier the feature extractor is changed according to the estimated quality of the bio-signal. 1. A physiological monitoring device comprising:a physiological sensor configured to sense a physiological feature to generate a bio-signal;a quality estimator estimating quality of the bio-signal; anda feature extractor receiving the bio-signal and performing a predetermined operation to the bio-signal to obtain feature data,wherein an amount of computation induced by the predetermined operation for the feature extractor is changed according to the estimated quality of the bio-signal.2. The physiological monitoring device as claimed in claim 1 , wherein the estimated quality of the bio-signal is represented by a value claim 1 , and when the quality estimator determines that the value is larger than a threshold claim 1 , the amount of computation induced by the predetermined operation is decreased.3. The physiological monitoring device as claimed in claim 1 ,wherein the estimated quality of the bio-signal is represented by a value, andwherein when the quality estimator determines that the value is larger than a threshold during a first period, the quality estimator generates a control signal to disable the feature extractor during the first period to decrease the amount of computation induced by the predetermined operation.4. The physiological monitoring device as claimed in claim 1 , further comprising:a switch, coupled between the physiological sensor and the feature ...

Dynamically calibrated blood pressure reference value electronic sphygmomanometer

The invention is an electronic sphygmomanometer that dynamically calibrates for a real-time standard blood pressure reference value, which is determined based on the objective condition of human blood pressure fluctuation influenced by various factors such as age, date and time of measurement, and establishes age/blood pressure reference value, date/blood pressure reference value and time/blood pressure reference. The value database, or through mathematical operations, obtains the real-time standard blood pressure reference value under the specific conditions of the subject's age, test date, and test time, and calibrates it as a benchmark for judging the abnormality state of the real-time blood pressure measurement value. This improves the ability of the sphygmomanometer in producing an accurate judgement of the subject's blood pressure, and reduces the margin of error for false positive tests or false negative tests. 1. Proposed is a type of dynamically calibrated blood pressure reference value electronic sphygmomanometer that dynamically calibrates in reference to real-time blood pressure standards , including blood pressure data acquisition , an MCU and a display; the reference standard blood pressure determined by age , date (month) and measurement time; the MCU is configured to dynamically calibrate based on real-time blood pressure and the real-time standard blood pressure reference to analyze the blood pressure reference value deviation in order to describe the abnormality of the real-time blood pressure status; the real-time blood pressure reference value is determined by the MCU through the “age/blood pressure reference value database ,” the “date/blood pressure reference value database” and the “measurement time/blood pressure reference database” association calibration , or according to the “age/blood pressure reference value function curve ,” “Date/blood pressure reference value function curve” and “time/blood pressure reference value function curve” and ...

Method and system for screening and monitoring of cardiac diseases

Embodiments herein provide a system and method for screening and monitoring of cardiac diseases by analyzing acquired physiological signals. Unlike state of art approaches that consider only synchronized ECG and PPG signals for cardiac health analysis and do not consider PCG which is a critical signal for CAD analysis, the system synchronously captures physiological signals such as photo plethysmograph (PPG), phonocardiogram (PCG) and electrocardiogram (ECG) from subject(s) and builds an analytical model in the cloud for analyzing heart conditions from the captured physiological signals. The system and method provides a fusion based approach of combining the captured physiological signals such as PPG, PCG and ECG along with other details such as subject clinical information, demography information and so on. The analytical model is pretrained using ECG. PPG and PCG along with metadata associated with the subject such as demography and clinical information.

WEARABLE MONITORING DEVICES WITH PASSIVE AND ACTIVE FILTERING

A wearable device includes a housing with a window and an electronic module supported by the housing. The electronic module includes a photoplethysmography sensor, a motion sensor, and a signal processor that processes signals from the motion sensor and signals from the photoplethysmography sensor. The signal processor is configured to remove frequency bands from the photoplethysmography sensor signals that are outside of a range of interest using a band-pass filter to produce pre-conditioned signals, and to further process the pre-conditioned signals using the motion sensor signals to reduce motion artifacts from footsteps during subject running. The device includes non-air light transmissive material in optical communication with the photoplethysmography sensor and the window that serves as a light guide for the photoplethysmography sensor. The window optically exposes the photoplethysmography sensor to a body of a subject wearing the device via the non-air light transmissive material. 1. An ear-worn device , comprising:a housing comprising at least one window;an electronic module supported by the housing, the electronic module comprising at least one photoplethysmography (PPG) sensor, at least one motion sensor, and at least one signal processor configured to process signals from the at least one motion sensor and signals from the at least one PPG sensor, wherein the at least one signal processor is configured to remove frequency bands from the signals from the at least one PPG sensor that are outside of a range of interest using at least one band-pass filter to produce pre-conditioned signals, and to further process the pre-conditioned signals using the signals from the at least one motion sensor to reduce motion artifacts from footsteps during subject running; andnon-air light transmissive material in optical communication with the at least one PPG sensor and the window that serves as a light guide for the at least one PPG sensor, wherein the at least one ...

AUTOMATIC METHOD TO DELINEATE OR CATEGORIZE AN ELECTROCARDIOGRAM

Disclosed is a method for computerizing delineation and/or multi-label classification of an ECG signal, including: applying a neural network to the ECG, labelling the ECG, and optionally displaying the labels according to time with the ECG signal.

METHOD AND APPARATUS FOR MONITORING A HUMAN OR ANIMAL SUBJECT

Methods and apparatus for monitoring a human or animal subject are disclosed. In one arrangement, measurement data representing a time series of measurements on a subject is received. The measurement data is represented as a mathematical expansion comprising a plurality of expansion components and expansion coefficients. First and second partial reconstructions are performed using first and second subsets of the expansion components. First and second spectral analyses are performed on the first and second partial reconstructions to determine first and second dominant frequencies. A frequency of a periodic physiological process is derived based on either or both of the first and second dominant frequencies. 1. A computer-implemented method of monitoring a human or animal subject , comprising:(a) receiving measurement data representing a time series of measurements on a subject performed by a sensor system;(b) processing the measurement data to represent the measurement data as a mathematical expansion comprising a plurality of expansion components and a corresponding plurality of expansion coefficients representing the respective strength of each expansion component;(c1) forming a first partial reconstruction of the measurement data using a first subset of the expansion components and corresponding expansion coefficients;(c2) forming a second partial reconstruction of the measurement data using a second subset of the expansion components and corresponding expansion coefficients, the second subset being different from the first subset;(d1) performing a first spectral analysis on the first partial reconstruction to determine a first dominant frequency, the first dominant frequency representing a frequency component of largest amplitude in the first partial reconstruction;(d2) performing a second spectral analysis on the second partial reconstruction to determine a second dominant frequency, the second dominant frequency representing a frequency component of largest ...

A SYSTEM AND METHOD FOR DETERMINING POWER AND PROPULSION EFFICIENCY OF A LIMB DURING LIMBED PROPULSION

The present invention provides a system for determining power output and propulsion efficiency of a user's limb during limbed propulsion; the system comprising: (a) at least two or more accelerometers to measure the acceleration of the limb in at least two substantially orthogonal planes, (b) a processor means to calculate the power output generated by the limb to derive a limb propulsion efficiency measure, and (c) a transmission means to send the limb power output and limb propulsion efficiency metrics to a receiving device; and wherein the system is wearable on the user's limb.

SYSTEM AND METHOD FOR MONITORING CEREBRAL ACTIVITY

A patient monitor for monitoring cerebral activity of a patient may include a processor configured to determine a depth of consciousness index for the patient based on electroencephalography (EEG) data and determine regional oxygen saturation for the patient based on regional oximetry data. Additionally, the processor may be configured to determine a metric associated with cerebral activity of the patient based at least in part on the one or more values of the depth of consciousness index and the one or more regional oxygen saturation values and to provide the one or more values of a depth of consciousness index and the metric to an output device. 1. An electroencephalography (EEG) monitor , comprising:a memory encoding one or more processor-executable routines; and receive electroencephalography (EEG) data from an EEG sensor configured acquire the EEG data from a patient;', 'determine a depth of consciousness index for the patient based on the EEG data, wherein the depth of consciousness index is indicative of a level of consciousness of the patient under general anesthesia;', 'determine a regional oxygen saturation value for the patient based on regional oximetry data;', 'determine a value of a Pearson correlation coefficient for the regional oxygen saturation value and the depth of consciousness index over a predetermined period of time, wherein the value of the Pearson correlation coefficient is indicative of a correlation between the regional oxygen saturation value and the depth of consciousness index;', 'determine a confidence level for the depth of consciousness index based at least in part on the value of the Pearson correlation coefficient, wherein the confidence level is indicative of a reliability of the depth of consciousness index; and', 'provide the depth of consciousness index and the confidence level to an output device for display of the depth of consciousness index and the confidence level., 'a processor configured to access and execute the one or ...

SYSTEM AND METHOD OF MONITORING AUTOREGULATION

A method for monitoring autoregulation includes using a processor for receiving blood pressure data and oxygen saturation data from a patient, fitting a dynamic model to the blood pressure data and the oxygen saturation data to determine one or more parameters of the dynamic model indicative of autoregulation, and determining the patient's autoregulation status based on the one or more parameters. 1. A method for monitoring autoregulation comprising: receiving blood pressure data and oxygen saturation data from a patient;', 'fitting a dynamic model to the blood pressure data and the oxygen saturation data to determine one or more parameters of the dynamic model indicative of autoregulation; and', "determining the patient's autoregulation status based on the one or more parameters."], 'using a processor for2. The method of claim 1 , wherein determining the patient's autoregulation status comprises comparing the one or more parameters to predetermined values claim 1 , ranges claim 1 , or thresholds.3. The method of claim 1 , comprising using the processor for determining a degree of impairment of the patient's autoregulation system.4. The method of claim 1 , wherein the dynamic model comprises a differential equation model.5. The method of claim 1 , wherein the dynamic model comprises a damped dynamic oscillator model.6. The method of claim 1 , wherein the dynamic model has the following form:{'br': None, 'i': A{umlaut over (x)}', '+B{dot over (x)}', 'Cx', '+D=P*,, 'sup': a', 'b', 'c}where x is an oxygen saturation value, P* is a pressure forcing function, D is a constant, and A, a, B, b, C, and c are parameters.7. The method of claim 1 , wherein the dynamic model comprises a finite element model claim 1 , a finite difference model claim 1 , a wave tracing model claim 1 , or a delay differential equation.8. The method of claim 1 , comprising using the processor for constructing the dynamic model based on empirical data.9. The method of claim 1 , comprising using the ...

METHODS AND DEVICES FOR ACCURATELY CLASSIFYING CARDIAC ACTIVITY

Methods, systems, and devices for signal analysis in an implanted cardiac monitoring and treatment device such as an implantable cardioverter defibrillator. In some examples, captured data including detected events is analyzed to identify likely overdetection of cardiac events. In some illustrative examples, when overdetection is identified, data may be modified to correct for overdetection, to reduce the impact of overdetection, or to ignore overdetected data. Several examples emphasize the use of morphology analysis using correlation to static templates and/or inter-event correlation analysis. 1. (canceled)2. An implantable medical device (IMD) comprising a plurality of electrodes coupled to operational circuitry configured to perform cardiac signal analysis , the IMD including a canister having the operational circuitry and at least one electrode associated therewith , the operational circuitry being configured to:detect a cardiac cycle by comparison of a cardiac signal from the plurality of electrodes to a threshold, thereby declaring a detected event having a signal waveform; selecting a first fiducial point in the signal waveform corresponding to a first fiducial point in the template and using the first fiducial points to align the signal waveform and the template to perform a first comparison yielding a first comparison score;', 'selecting a second fiducial point in the signal waveform corresponding to a second fiducial point in the template and using the second fiducial points to align the signal waveform and the template to perform a second comparison yielding a second comparison score; and', 'selecting whichever of the first and second comparison scores is greater to generate the correlation score; and, 'compare the signal waveform to a template having a plurality of fiducial points in a correlation analysis to yield a correlation score bydetermine, using the correlation score, whether the detected cardiac event is indicative of an arrhythmic condition.3. ...

Method and system for pacing pulse detection and pacing artifact rejection

A method and system for detecting pacing pulses originating from implanted pacemaker using surface Electrocardiogram (ECG) signals measured at a relatively low sampling rate and also rejecting the pacing artifacts from the recorded surface ECG signals.

WEARABLE CARDIOVERTER DEFIBRILLATOR (WCD) SYSTEM INFORMING PATIENT THAT IT WILL NOT SHOCK RESPONSIVE TO JUST-SELF-TERMINATED CARDIAC ARRHYTHMIA

In some embodiments, a wearable cardioverter defibrillator (“WCD”) system may output an opening human-perceptible indication, after detecting a shockable cardiac arrhythmia but before validating it. This may succeed in informing the patient that the WCD system is working, and in particular analyzing a just-detected cardiac arrhythmia. The information may give comfort and confidence to the patient who may be conscious, and be experiencing only ventricular tachycardia but not ventricular fibrillation. 1138-. (canceled)139. A wearable cardioverter defibrillator (“WCD”) system , comprising:a support structure configured to be worn by a patient;a power source;an energy storage module configured to be coupled to the support structure, to be charged from the power source and to store an electrical charge;a discharge circuit coupled to the energy storage module, the discharge circuit controllable to discharge the electrical charge so as to cause a shock to be delivered to the patient;a measurement circuit configured to render a physiological input from a patient physiological signal;a user interface configured to output one or more human-perceptible indications; and detect a cardiac arrhythmia of the patient from the physiological input;', 'determine whether a type of the cardiac arrhythmia is at least one of a first type (“CA1”) and a second type (“CA2”);', 'if the type is CA1, cause a first human-perceptible indication to be output, else if the type is CA2, cause a second human-perceptible indication to be output, the second human-perceptible indication being different from the first human-perceptible indication; and', 'then control the discharge circuit to deliver a shock responsive to the cardiac arrhythmia., 'a processor configured to140. The WCD system of claim 139 , in whichCA1 includes Ventricular Fibrillation.141. The WCD system of claim 139 , in whichCA1 includes Ventricular Tachycardia, where a heart rate of the patient has a value larger than a first heart rate ...

EVALUATING IMPEDANCE MEASUREMENTS

An impedance measurement system for performing a bioimpedance measurement on a biological subject, the system including a signal generator configured to apply alternating signals to at least part of the biological subject at a plurality of different frequencies, a sensor configured to measure response signals from the biological subject and one or more electronic processing devices that determine impedance values obtained at the plurality of different frequencies using the measured response signals, calculate an impedance curve using a curve fitting algorithm, determine a deviation of the impedance curve from the impedance measurements and use the deviation to perform an evaluation of the impedance measurements. 1) An impedance measurement system for performing a bioimpedance measurements on a biological subject , the system including:a) a signal generator configured to apply alternating signals to at least part of the biological subject at a plurality of different frequencies;b) a sensor configured to measure response signals from the biological subject; and, i) determine impedance values obtained at the plurality of different frequencies using the measured response signals;', 'ii) calculate an impedance curve using a curve fitting algorithm;', 'iii) determine a deviation of the impedance curve from the impedance measurements; and,', 'iv) use the deviation to perform an evaluation of the impedance measurements., 'c) one or more electronic processing devices that2) (canceled)3) A system according to claim 1 , wherein the evaluation of the impedance measurements is used to at least one of:a) determine an impedance measurement validity;b) categorise the impedance measurement;c) cause the impedance measurement to be repeated; and, i) a measurement validity;', 'ii) a measurement error; and,', 'iii) a measurement categorisation., 'd) derive an indicator indicative of at least one of4) A system according to claim 1 , wherein the impedance measurement is categorised as ...

METHODS AND APPARATUS FOR DETECTION OF DISORDERED BREATHING

Methods and apparatus provide monitoring of a sleep disordered breathing state of a person such as for screening. One or more sensors may be configured for non-contact active and/or passive sensing. The processor(s) () may extract respiratory effort signal(s) from one or more motion signals generated by active non-contact sensing with the sensor(s). The processor(s) may extract one or more energy band signals from an acoustic audio signal generated by passive non-contact sensing with the sensor(s). The processor(s) may assess the energy band signal(s) and/or the respiratory efforts signal(s) to generate intensity signal(s) representing sleep disorder breathing modulation. The processor(s) may classify feature(s) derived from the one or more intensity signals to generate measure(s) of sleep disordered breathing. The processor may generate a sleep disordered breathing indicator based on the measure(s) of sleep disordered breathing. Some versions may evaluate sensing signal(s) to generate indication(s) of cough event(s) and/or cough type. 1. A method of one or more processors for monitoring a sleep disordered breathing state of a person , the method in the one or more processors comprising:extracting one or more respiratory signals from one or more motion signals, the one or more motion signals generated by active non-contact sensing;extracting one or more energy band signals from a passive signal, the passive signal generated by passive non-contact sensing, the passive signal representing acoustic information detected by a sound sensor;assessing the one or more energy band signals and/or the one or more respiratory signals to generate one or more intensity signals representing intensity of sleep disorder breathing modulation; andclassifying, or transmitting for classification, one or more features derived from the one or more intensity signals to generate one or more measures of sleep disordered breathing.2. The method of further comprising any one or more of:(a) ...

Methods For Determining Disease Risk Combining Downsampling of Class-Imbalanced Sets With Survival Analysis

A method for downsampling class-imbalanced sets with survival analysis comprising: acquiring a class-imbalanced data set, wherein the class-imbalanced data set comprises biological data from a plurality of subjects, wherein the biological data of each subject includes an observation, a time value, and a plurality of clinical measurements, and wherein the biological data is categorized as being part of a majority data class or a minority data class, wherein the majority data class has a greater number of observations than the minority data class; downsampling the class-imbalanced data set, wherein the downsampling results in the majority data class having an equivalent or substantially equivalent number of observations as the minority data class; and performing cross-validation on the downsampled data set with a survival analysis to generate a survival model, wherein the observation comprises an event or no event at a specific time value. 1. A method comprising:a) acquiring a class-imbalanced data set, wherein the class-imbalanced data set comprises biological data from a plurality of subjects, wherein the biological data of each subject includes an observation, a time value, and a plurality of clinical measurements, and wherein the biological data is categorized as being part of a majority data class or a minority data class, wherein the majority data class has a greater number of observations than the minority data class;b) downsampling the class-imbalanced data set to generate a downsampled data set, wherein the downsampling results in the majority data class having an equivalent or substantially equivalent number of observations as the minority data class; andc) performing cross-validation on the downsampled data set with a survival analysis to generate a survival model;wherein the observation comprises an event or no event at a specific time value, wherein an AUC, sensitivity, specificity, and/or C-index of the survival model is closer to 1 than a AUC, ...

Methods, systems and non-transitory computer-readable recording media for monitoring blood pressure in real time

Methods, systems, and non-transitory computer-readable recording media for monitoring blood pressure are provided. The method includes calculating an estimate of deviations between every two pulse transit time (PTT) values measured at an interval of a first period, and estimating a PTT value to be measured the first period after a current time. The method also includes calculating an estimate of deviations between every two oxygen saturation values measured at an interval of a second period, and estimating an oxygen saturation value to be measured the second period after the current time. The method additionally includes calculating current systolic blood pressure and diastolic blood pressure based on an electrocardiogram (ECG) value measured at the current time, the estimated PTT value, and the estimated oxygen saturation value.

FAST SCANING BASED ON MAGNETIC RESONANCE HISTORY

During operation, a system iteratively captures MR signals of one or more types of nuclei in one or more portions of a biological lifeform based on scanning instructions that correspond to a dynamic scan plan. The MR signals in a given iteration may be associated with voxels having associated sizes at three-dimensional (3D) positions in at least a corresponding portion of the biological lifeform. If the system detects a potential anomaly when analyzing the MR signals from the given iteration, the system dynamically modifies the scan plan based on the detected potential anomaly, a medical history and/or an MR-scan history. Subsequent measurements of MR signals may be associated with the same or different: types of nuclei, portions of the biological lifeform, voxels sizes and/or 3D positions. 1. A system to perform a magnetic-resonance (MR) scan , comprising:an MR scanner that, during operation, is configured to perform one or more MR scans of at least a first portion of a biological lifeform;an interface circuit electrically coupled to the MR scanner, wherein, during operation, the interface circuit is configured to communicate information with the MR scanner, and provide, to the MR scanner, first scanning instructions based on an initial scan plan to capture first MR signals of one or more first types of nuclei in at least the first portion of the biological lifeform, wherein the first MR signals are associated with first voxels having first sizes at first three-dimensional (3D) positions in at least the first portion of the biological lifeform;', 'receive, from the MR scanner, the first MR signals;', 'analyze the first MR signals to detect a potential anomaly in the first MR signals based on one or more of: a medical history of the biological lifeform; an MR-scan history of the biological lifeform that includes prior MR scans of the biological lifeform; and a first template of a potential anomaly;', 'dynamically modify the initial scan plan based on one or more of ...

Electrical-signal-based electrode-tissue contact detection

A method includes disposing a pair of current-application electrodes in or on a body, including disposing an intrarenal current-application electrode of the pair in a renal artery. Two or more sensing electrodes are disposed in or on the body, including disposing one of the sensing electrodes on en external surface of skin. Control circuitry is activated to (a) apply an electrical current between the pair of current-application electrodes, (b) while applying the electrical current, sense an electrical signal between the sensing electrodes, including the sensing electrode disposed on the external surface of the skin, and (c) based on the electrical signal, ascertain a level of contact between the intrarenal current-application electrode and a wall of the renal artery. In response to the level of contact being less than a threshold level of contact, a disposition of the intrarenal current-application electrode in the renal artery is adjusted.

METHOD AND APPARATUS FOR MEASUREMENT OF CARDIOPULMONARY FUNCTION

A method for measuring anatomical dead space in a lung, the method comprising: 148-. (canceled)49. A method for adjusting ventilator settings in a ventilated patient based on information obtained by measuring anatomical dead space Vin a lung , the method comprising:delivering, through a breathing tube a supply of inspired gas, to the ventilated patient for inhalation; injecting, by a flow control means, the indicator gas into the supply of inspired gas via the breathing tube;', 'processing, by a processing unit, a measured flow rate and concentration of the inspired indicator gas over each breath so as to determine, from breath to breath, an injection rate for the inspired indicator gas that will cause the inspired indicator gas to follow the sinewave pattern, and', 'injecting the indicator gas, by the flow control means, at the determined injecting rate caused by a feedback control from a gas mixing controller to the flow control means, the feedback control based on the measured flow rate, concentration of the inspired indicator gas, the injection rate from the mass flow controller, the supply of the inspired gas, and feedback from a flow sensor and a gas analyzer each in communication with the breathing tube;, 'controlling concentration of an indicator gas for inhalation by a mass flow controller to follow a sinewave pattern over successive breaths, bymeasuring, by the flow sensor and the gas analyzer, the flow rate and concentration of the indicator gas during inspiration and exhalation of the patient;{'sub': I', 'Ē', 'E, 'fitting sinewave envelopes to the measured concentration of the indicator gas over the successive breaths and, from the fitted sinewave envelopes, determining, by the system controller, the inspired concentration F, the mixed expired concentration F, and the end expired concentration Fwith respect to the indicator gas for each breath; and'} [{'sub': T', 'T, 'calculating a tidal volume Vby integrating over time, from the start of a respective ...

Electrocardiogram information processing method and electrocardiogram workstation system

An electrocardiogram information processing method and workstation system. The method includes receiving electrocardiogram data output by multiple devices; performs data analysis on the electrocardiogram data, and generating report data and stores same; receiving a report data query by a user, queries corresponding report data according to a user ID of the user, and generating report result list for display and output; receiving a selection by the user, and obtaining selected report data according to the selection; receiving a report data consultation request input by the user; obtaining a user ID of an associated user corresponding to the user ID according to the report data consultation request, and sending the report data to a user equivalent of the associated user according to the user ID of the associated user; and receiving a consultation result feedback data sent by the user equivalent of the associated user.

Methods and Systems for Mapping Cardiac Activity

Cardiac activity can be mapped by receiving an electrogram, transforming the electrogram into the wavelet domain (e.g., using a continuous wavelet transformation) to create a scalogram of the electrogram, computing at least one energy function of the scalogram, and computing at least one metric of the electrogram using the at least one energy function. The metrics of the electrogram can include, without limitation: a QRS activity duration for the electrogram; a near-field component duration for the electrogram; a far-field component duration for the electrogram; a number of multiple components for the electrogram; a slope of a sharpest component of the electrogram; a scalogram width; an energy ratio in the electrogram; and a cycle-length based metric of the electrogram. 121-. (canceled)22. A method of mapping cardiac activity , comprising:receiving a plurality of electrogram signals S(t) at an electroanatomical mapping system; and compute a scalogram G(f, t);', 'compute an energy function L(t) of the scalogram G(f, t);', {'sup': 'Pulse', 'compute a pulse wave L(t) of the energy function L(t);'}, {'sup': 'Pulse', 'compute a metric of the electrogram signal S(t) using the pulse wave L(t); and'}], 'for each of the plurality of electrogram signals S(t), using the electroanatomical mapping system tooutputting a graphical representation of the metrics for the plurality of electrogram signals on a graphical representation of a cardiac model.23. The method according to claim 22 , wherein the pulse wave L(t) has a value of 1 if the energy function L(t) has a value greater than 0 claim 22 , and a value of 0 otherwise.24. The method according to claim 22 , wherein the metric comprises a QRS duration of the electrogram signal S(t) claim 22 , and wherein the electroanatomical mapping system defines the QRS duration of the electrogram signal S(t) to be equal to a pulse duration of the pulse wave L(t).25. The method according to claim 22 , wherein the metric comprises a near-field ...

MULTIPLE WAVELENGTH SENSOR EMITTERS

A physiological sensor has light emitting sources, each activated by addressing at least one row and at least one column of an electrical grid. The light emitting sources are capable of transmitting light of multiple wavelengths and a detector is responsive to the transmitted light after attenuation by body tissue.

Methods for Monitoring Carboxyhemoglobin, Inspired and Expired CO2 and Calibration of Non-Invasive Arterial O2 Saturation

The present invention is directed to system and method for effectively monitoring critical respiratory parameters including SpO, PR, COHb, inspired CO, expired CO, respiration rate, respiration pattern, hyperventilation (hypocapnia), hypoventilation (hypercapnia), COcontamination, and COrebreathing. The system according to the present invention comprises a pulse oximetry sensor and a COsensor connected to a central portable unit. The central unit comprising a barometer, an accelerometer, a capnography circuit, and a control unit. The control unit including the method for effectively monitoring critical respiratory parameters. 1. A method for monitoring hypocapnia and hypercapnia in an aircraft's pilot , the method comprising:{'sub': '2', "configuring a COsensor in an aviator's mask of the pilot;"}{'sub': 2', '2, 'receiving, by a capnography circuitry, COwaveforms data from the COsensor; and'}{'sub': 2', '2', '2', '2, 'determining, by the capnography circuitry, based on the COwaveforms, respiratory rate, respiratory pattern, end tidal CO, hyperventilation, hypoventilation, hypocapnia, hypercapnia, COcontamination and COrebreathing.'}2. A system comprising:a housing;a control unit enclosed in the housing;a pulse oximetry sensor operably coupled to the control unit, the pulse oximetry sensor removably configured in a head gear;a barometer operably coupled to the control unit; andan accelerometer operably coupled to the control unit, [{'sub': '2', 'receive SpOvalues, PR values, signal strength value and a signal quality value from the pulse oximetry sensor, the pulse oximetry sensor positioned over an arterial microcirculation of blood in a forehead of an aircraft pilot, the microcirculation of blood detected by using an infrared (IR) photometric technique,'}, 'create indices corresponding to an altitude index (AI), a vibration index (VI) and a gravitation index (GI) under a controlled condition of hypobaria as well as a varying condition of hypobaria,', 'create a scale ...

Method and device for fingerprint authentication

A fingerprint authentication method includes a first step of acquiring partial fingerprint measurement data for a part of a fingerprint, and a second step of calculating a matching rate by comparing the partial fingerprint measurement data with reference comparison data selected among a plurality of partial fingerprint registration data, each partial fingerprint registration data corresponding to a part of a fingerprint. The method further includes a third step of determining whether the matching rate is equal to or greater than an authentication threshold and a fourth step of determining, based on a result in the third step, a success of the authentication, or repeating the second and third steps by selecting new reference comparison data based on whether or not the matching rate is equal to or greater than a preset threshold smaller than the authentication threshold.

Determining Tissue Oxygen Saturation with Quality Reporting

An oximeter probe determines an oxygen saturation for the tissue and determines a quality value for the oxygen saturation and associated measurements of the tissue. The quality value is calculated from reflectance data received at the detectors of the oximeter probe. The oximeter probe then displays a value for the oxygen saturation with the error value to indicate a quality level for the oxygen saturation and associated values used to calculate oxygen saturation. 1. A method comprising:providing an oximeter device, wherein the oximeter device is wireless and comprises a nonvolatile memory, data points for simulated reflectance curves are stored in the nonvolatile memory, and the nonvolatile memory retains the data points for the simulated reflectance curves even when the device is powered off;using the oximeter device, making a oxygen saturation measurement of a tissue comprising emitting light from a source of the oximeter device into the tissue, and receiving light reflected from the tissue at detectors of the oximeter device in response to the emitted light, wherein a plurality of detector responses is obtained for the reflected light;fitting the detector responses to the data points for the simulated reflectance curves stored in the nonvolatile memory to determine an absorption coefficient value for the tissue;using the absorption coefficient value, determining an oxygen saturation value for the tissue;calculating an error value from the fitting of the detector responses to the simulated reflectance curves, and using the error value, determining a quality metric value for the oxygen saturation value; anddisplaying on a screen the oxygen saturation value and the quality metric value.2. The method of comprising when determining the quality metric value claim 1 , performing a ratiometric calculation.3. The method of wherein calculating the error value comprises using a Tiknonov regularization calculation.4. The method of wherein the quality metric value is ...

Combined Optical Sensor for Audio and Pulse Oximetry System and Method

A system includes at least one earpiece, wherein each earpiece comprises an earpiece housing, an optical source operatively connected to the earpiece housing, wherein the optical source is configured to emit light toward an ear surface, an optical sensor operatively connected to the earpiece housing, wherein the optical sensor is configured to receive reflected light from the ear surface, and at least one processor disposed within at least one earpiece and operatively connected to the optical source and the optical sensor, wherein the at least one processor is configured to separate the pulse oximetry signals from the audio signals in the reflected light detected by the optical sensor. 1. A system comprising:at least one earpiece, wherein each earpiece comprises an earpiece housing;an optical source operatively connected to the earpiece housing, wherein the optical source is configured to emit light toward an ear surface;an optical sensor operatively connected to the earpiece housing, wherein the optical sensor is configured to receive reflected light from the ear surface; andat least one processor disposed within at least one earpiece and operatively connected to the optical source and the optical sensor, wherein the at least one processor is configured to separate the pulse oximetry signals from the audio signals in the reflected light detected by the optical sensor.2. The system of wherein the at least one processor is further configured to determine an oxygen saturation level from the pulse oximetry signals.3. The system of wherein the at least one processor applies a filter to separate the pulse oximetry signals from the audio signals claim 1 , the audio signals centered at frequency higher than the pulse oximetry signals.4. The system of wherein the at least one earpiece comprises a set of earpieces.5. The system of wherein the optical source is a laser.6. The system of wherein the ear surface comprises an outer ear surface.7. The system of wherein the ear ...

METHOD OF ESTIMATION OF THE QUALITY OF A HEART RATE SIGNAL

The present disclosure concerns a method of estimation, by means of an electronic processing device (), of the quality of a heart rate signal delivered by a heart rate sensor during an acquisition phase of duration W, said signal including a sequence of N samples IBIeach having a value representative of a duration between two successive heartbeats detected by the sensor, N being an integer greater than or equal to 2 and i being an integer in the range from 1 to N, the method including a step of calculating, by means of the electronic processing device, of a default indicator L representative of the difference between duration W of the acquisition phase and the sum of the values of the samples IBIof the signal. 1. A method of estimation , by means of an electronic processing device , of the quality of a heart rate delivered by a heart rate sensor during an acquisition phase of duration W , said signal being delivered rid of possible outliers and comprising a sequence of N samples IBIeach having a value representative of a duration between two successive heartbeats detected by the sensor , N being an integer greater than or equal to 2 and i being an integer in the range from 1 to N , the method comprising a step of calculation , by means of the electronic processing device of a ratio or a difference between duration W of the acquisition phase and the sum of the values of the samples IBIof the signal and a step of delivery of a default indicator L which is a function of this ratio or of this difference.2. The method according to claim 1 , wherein the default indicator L is representative of a percentage of heartbeats missed by the sensor during the acquisition phase.4. The method of claim 1 , wherein the duration W of the acquisition phase is in the range from 20 to 120 seconds.5. The method of claim 1 , further comprising a step of comparison of default indicator L with a predefined threshold TH and a step of decision claim 1 , based on the result of the comparison ...

SYSTEMS AND METHODS FOR MANAGING PATIENT-TRIGGERED EPISODES

Systems and methods for managing machine-generated medical events detected from one or more patients are described herein. A medical event management system includes an event analyzer circuit to detect a medical event using physiological data from a patient-triggered episode acquired from a medical device. The event analyzer circuit determines a confidence score of the medical event detection, and generates an alignment indicator indicating a degree of concordance between the detected medical event and the information about the patient-triggered episode. The system assigns priority information to the patient-triggered episode using the generated alignment indicator and the confidence score of the detection. An output circuit can output the received physiological information to a user or a process according to the assigned priority information. 1. A system for prioritizing medical events detected by an ambulatory medical device (AMD) , the system comprising:a receiver circuit configured to receive physiological information from the AMD corresponding to a patient-triggered episode;an event analyzer circuit configured to analyze the received physiological information corresponding to the patient-triggered episode, and to determine a confidence score for the patient-triggered episode; andan event prioritizer circuit configured to assign priority information to the received patient-triggered episode using the confidence score.2. The system of claim 1 , wherein the event analyzer circuit is configured to perform offline analysis of the received physiological information corresponding to the patient-triggered episode.3. The system of claim 1 , wherein the patient-triggered episode includes information about patient-reported sign or symptom claim 1 , and the event analyzer circuit is configured to detect a medical event and generate an alignment indicator indicating a concordance between the information about patient-reported sign or symptom and the detected medical event.4 ...

Methods and apparatus for detecting motion noise and for removing motion noise from physiological signals

A monitoring apparatus includes a housing that is configured to be attached to a body of a subject. The housing includes a sensor region that is configured to contact a selected area of the body of the subject when the housing is attached to the body of the subject. The sensor region is contoured to matingly engage the selected body area. The apparatus includes at least one physiological sensor that is associated with the sensor region and that detects and/or measures physiological information from the subject and/or at least one environmental sensor associated with the sensor region that is configured to detect and/or measure environmental information. The sensor region contour stabilizes the physiological and/or environmental sensor(s) relative to the selected body area such that subject motion does not impact detection and/or measurement efforts of the sensor(s).

AUTOMATIC METHOD TO DELINEATE OR CATEGORIZE AN ELECTROCARDIOGRAM

Disclosed is a method for computerizing delineation and/or multi-label classification of an ECG signal, including: applying a neural network to the ECG, labelling the ECG, and optionally displaying the labels according to time with the ECG signal. 1. A system for detecting anomalies in an electrocardiogram (ECG) signal corresponding to a patient , the system comprising at least one server and at least one processor configured to execute instructions to:receive the ECG signal sampled from the patient over a plurality of time points;determine delineation scores at each time point of the plurality of time points of at least a portion of the ECG signal, the delineation scores corresponding to multiple wave types at each time point;determine anomaly scores based on the at least a portion of an ECG signal and the delineation scores, the anomaly scores corresponding to multiple anomaly types;determine that an anomaly corresponding to one of the multiple anomaly types is present in the ECG signal based on at least one of the anomaly scores corresponding to a first time point of the plurality of time points; andgenerate information for display comprising a graphical representation of the at least a portion of the ECG signal and a visual indication of the anomaly corresponding to the graphical representation of the at least a portion of the ECG signal at the first time point of the plurality of time points.2. The system of claim 1 , wherein determining that the anomaly is present in the ECG signal comprises determining that atrial fibrillation is present in the ECG signal.3. The system of claim 1 , wherein the visual indication of the anomaly is aligned with a location of the anomaly on the graphical representation of the at least a portion of the ECG signal.4. The system of claim 1 , wherein the at least one processor is further configured to execute instructions to:determine that a second anomaly corresponding to a second one of the multiple anomaly types and different from ...

ENDOSCOPE SYSTEM AND OPERATION METHOD THEREFOR

Provided is an endoscope system capable of easily re-searching for a detected region of interest, and an operation method for the endoscope system. An endoscope system includes an endoscopic image acquisition unit , a region-of-interest detecting unit , a position information acquisition unit , and a display unit . The endoscopic image acquisition unit acquires an endoscopic image acquired by capturing an image of a lumen with an endoscope . The region-of-interest detecting unit detects a region of interest in the lumen by using the endoscopic image. The position information acquisition unit acquires position information of the region of interest detected by the region-of-interest detecting unit . The display unit displays the position information of the region of interest. 1. An endoscope system comprising:an endoscope;an endoscopic image acquisition unit that acquires an endoscopic image acquired by capturing an image of a lumen with the endoscope;a region-of-interest detecting unit that detects a region of interest in the lumen by using the endoscopic image;a position information acquisition unit that acquires position information of the region of interest; anda display unit that displays the position information of the region of interest.2. The endoscope system according to claim 1 , comprising:a first marked image generating unit that generates a first marked image having a marking at a position corresponding to the position information of the region of interest in a schematic diagram of the lumen, whereinthe display unit displays the first marked image.3. The endoscope system according to claim 2 , comprising:an insertion state acquisition unit that acquires an insertion state of the endoscope that is in the lumen, whereinthe display unit displays the insertion state of the endoscope at a corresponding position of the schematic diagram.4. The endoscope system according to claim 3 , comprising:a discrimination unit that performs discrimination on the region of ...

DEVICE AND METHOD TO DETERMINE BLOOD GLUCOSE SENSING DATA

Provided is a device and method to determine blood glucose sensing data. The device may determine whether blood glucose sensing data is an error candidate based on a sampling value and a sampling slope of the blood glucose sensing data, and finally determine whether the blood glucose sensing data is error data by applying a blood glucose signal determination model to the error candidate. 1. A method of determining blood glucose sensing data , the method comprising:collecting blood glucose sensing data corresponding to a predetermined time length; anddetermining whether the blood glucose sensing data is an error candidate, based on at least one of a sampling value and a sampling slope of the blood glucose sensing data.2. The method of claim 1 , wherein the collecting comprises receiving blood glucose sensing data including sampling values measured at a plurality of sampling points in a time series manner at predetermined time intervals.3. The method of claim 1 , wherein the determining comprises determining the blood glucose sensing data to be the error candidate claim 1 , in response to an example in which a count of sampling points included in the blood glucose sensing data is less than a threshold count.4. The method of claim 1 , wherein the determining comprises determining the blood glucose sensing data to be the error candidate claim 1 , in response to an example in which a sampling value exceeding a threshold waiting value is detected during a waiting interval of the blood glucose sensing data.5. The method of claim 1 , wherein the determining comprises determining the blood glucose sensing data to be the error candidate claim 1 , in response to an example in which a peak value of the blood glucose sensing data is out of a peak range.6. The method of claim 1 , wherein the determining comprises determining the blood glucose sensing data to be the error candidate claim 1 , in response to an absence of a peak point during a peak interval of the blood glucose ...

HEART RATE AND BLOOD OXYGEN MONITORING SYSTEM

An integrated circuit device includes an insulating body provided with a number of electrically conductive leads and having a surface provided with a red LED aperture, an IR LED aperture and a photodetector aperture. The insulating body also includes an optical isolator optically separating the photodetector aperture from the red LED aperture and the IR LED aperture. A red LED is aligned with the red LED aperture, an IR LED is aligned with the IR LED aperture, and a photodetector is aligned with the photodetector aperture. 1. An electronic device with heart rate monitor comprising:a body including at least one infrared (IR) transmissive surface;a digital processor located within the body;a display screen supported by the body;an IR light emitting diode (LED) aligned with the IR transmissive surface;LED driving circuitry coupled to the IR LED;an IR photodetector aligned with the IR transmissive surface;a filtering and amplification stage having an input coupled to the IR photodetector;an analog-to-digital converter (ADC) having an analog input coupled to an output of the filtering and amplification stage and a digital output; and (a) detecting that a finger has been placed on the IR transmissive surface using the IR LED and IR photodetector;', '(b) capturing raw data from the ADC;', '(c) performing a Fast Fourier Transform (FFT) of the raw data to develop FFT data;', '(d) processing the FFT data for at least one of window, averaging and noise rejection;', '(e) calculating a heart rate; and', '(f) at least one of displaying and storing the heart rate., 'memory coupled to the digital processor including code segments executable by the digital processor for2. An electronic device with heart rate monitor as recited in wherein the electronic device is a portable digital device and further comprises a wireless connection to a network.3. An electronic device with heart rate monitor as recited in wherein the network is at least one of a cellular telephone network and the ...

NON-LINEAR FILTERING FOR THE RECONSTRUCTION OF A SURFACE ELECTROCARDIOGRAM FROM AN ENDOCARDIAL ELECTROGRAM

An active medical device using non-linear filtering for the reconstruction of a surface electrocardiogram (ECG) from an endocardial electrogram (EGM) is disclosed. The device for the reconstruction of the surface ECG includes a plurality of inputs, receiving a corresponding plurality of EGM signals from endocardial or epicardial electrogram (x[n], x[n]), each collected on a respective EGM derivation of a plurality of EGM derivations, and at least one output delivering a reconstructed surface ECG electrocardiogram signal (y[n]), related to an ECG derivation, and a non-linear digital filter () with a transfer function that determines the reconstructed ECG signal based on said plurality of input EGM signals. The non-linear digital filter includes a Volterra filter type (″) whose transfer function includes a linear term (h) and at least one quadratic (h) and/or cubic (h) term(s). 1. A device for reconstructing a surface electrocardiogram (ECG) , the device comprising:a first linear filter receiving an input corresponding to endocardial or epicardial electrogram (EGM) signals;a second linear filter receiving the EGM signals squared, and/or a third linear filter receiving the same EGM signals cubed; anda linear combination of the filtered signals from the first, second and/or third linear filters of each EGM derivation, delivering as an output a reconstructed ECG signal.2. The device of claim 1 , comprising:receiving an additional linear filter optionally as an input corresponding to the EGM signals in each derivation.3. The device of claim 2 , comprising:linearly combining the filtered input signals by an additional linear filter with the filtered signals by the first, and one or both of the second and third linear filters in each EGM derivation.4. The device of claim 1 , comprising:using two EGM derivations as the inputs to reconstruct the ECG, including an atrial EGM derivation and a ventricular EGM derivation.5. The device of claim 4 , comprising:acquiring EGM signals ...

Dynamic bio impedance range adjustment for a medical device

This disclosure is directed to devices, systems, and techniques for dynamically adjusting a bio impedance measurement range. An example device includes a plurality of electrodes. The device also includes sensing circuitry configured to sense a bio impedance and processing circuitry. The processing circuitry is configured to apply an excitation signal to the sensing circuitry and, based on the application of the excitation signal, determine a sensed bio impedance value within a bio impedance measurement range. The processing circuitry is also configured to determine whether the sensed bio impedance value is within a predetermined portion of the bio impedance measurement range for a predetermined period of time and based on the sensed bio impedance value being within the predetermined portion of the bio impedance measurement range for the predetermined period of time, adjust the excitation signal.

METHOD AND SYSTEM FOR COLLECTING AND PROCESSING BIOELECTRICAL SIGNALS

A variation of a method for collecting and processing bioelectrical signals includes: establishing bioelectrical contact between a user and one or more sensors of a biomonitoring neuroheadset; monitoring contact characteristics of the one or more sensors based on bioelectrical signals detected at the one or more sensors; and providing feedback to the user based on the contact characteristics. A variation of a system for collecting and processing bioelectrical signals includes a set of sensors (e.g., electrodes) and a processing subsystem configured process the set of bioelectrical signals. 1. A system for electroencephalography electrode adjustment , comprising:a set of electrodes, wherein the electrodes are configured to measure electroencephalography (EEG) signals from a user head;an actuatable housing mounting the set of electrodes and configured to bias the electrodes against the user head; and determine a probabilistic model; and', receive a set of EEG signals acquired by the electrode;', 'determine a contact quality metric based on the set of EEG signals;', 'extract feature values for a set of features from the set of EEG signals;', 'determine a signal quality metric based on the feature values, using the probabilistic model; and', 'facilitate electrode adjustment in real time, based on the signal quality metric and the contact quality metric., 'for each electrode in the set], 'a processing system configured to2. The method of claim 1 , wherein facilitating electrode adjustment comprises controlling a user interface to present a notification generated based on at least one of the signal quality metric or the contact quality metric claim 1 , wherein the notification is presented when the signal quality metric falls below a threshold.3. The method of claim 1 , wherein the signal quality metric is determined asynchronously from the contact quality metric.4. The method of claim 1 , wherein the set of EEG signals comprises a response to a reference signal applied ...

CONNECTION QUALITY ASSESSMENT FOR EEG ELECTRODE ARRAYS

Systems, devices, and methods are provided to assess connection quality between the electrodes of a bioelectrical signal measurement and/or electrical stimulation device and the tissue, typically skin, of the subject. A test signal is provided to a first electrode, voltage differences between the first electrode and additional electrodes are determined, an impedance of the first electrode is determined based on the voltages differences, and the determined impedance indicates connection quality. This process is typically repeated for all of the electrodes to determine connection quality. The user or subject can be alerted if the connection quality is poor, and the bioelectrical signal that is recorded can be provided with data points indicating connection quality during the signal recording. 1(a) providing an electrical sensor or stimulator comprising a plurality of electrodes;(b) contacting the plurality of electrodes to tissue of a subject;(c) providing a test signal to the tissue of the subject through a first electrode of the plurality of electrodes;(d) determining, with a processor coupled to the plurality of electrodes, a voltage difference between the first electrode and only one other electrode of the plurality of electrodes in response to the test signal, wherein the voltage difference is determined with neither the first electrode nor the only one other electrode being a common ground or a common reference electrode;(e) determining, with a processor coupled to the plurality of electrodes, an impedance of the first electrode in response to the determined voltage difference between the first electrode and the only one other electrode of the plurality of electrodes;(f) repeating steps (d) and (e) for the first electrode and other electrodes of the plurality of electrodes; and(g) notifying, with an output device coupled to the processor, one or more of the subject or a user that connection quality of the first electrode is poor if the determined impedance of ...

AUTOMATED CONDITION SCREENING AND DETECTION

Embodiments are disclosed that enable an electronic device to instruct as user how to user one or more noninvasive sensors to measure one or more physiological parameters of a patient. In one embodiment, the measured parameters are used to obtain a diagnosis, such as a diagnosis of a critical congenital heart defect. 1. (canceled)2. A system for noninvasively measuring a physiological parameter of a user to facilitate a diagnosis , the system comprising:an electronic device comprising a display, a wireless transceiver, a memory device comprising processor-executable instructions stored thereon, and one or more hardware processors in communication with the display, the wireless transceiver, and the memory device; display, on the display, a request for at least one patient ID associated with a user;', 'receive an input including the at least one patient ID;', 'validate the at least one patient ID;', 'display, on the display, instructions to obtain a first measurement by positioning a first noninvasive sensor at a first measurement site on the user;', 'receive, from the first noninvasive sensor, first signals responsive to a first physiological characteristic of the user;', 'calculate a first measured physiological parameter responsive to the first signals;', 'display, on the display, instructions to obtain a second measurement by positioning a second noninvasive sensor at a second measurement site on the user;', 'receive, from the second noninvasive sensor, second signals responsive to a second physiological characteristic of the user;', 'calculate a second measured physiological parameter of the user responsive to the second signals;', 'display, on the display, the first and second measured physiological parameters;', 'transmit, via the wireless transceiver, at least the first and second measured physiological parameters, in association with the at least one patient ID, over a network to a clinician; and', 'initiate, with the wireless transceiver, a telemedicine ...

METHOD AND SYSTEM FOR HEALTH IMPROVEMENT USING TOILET SEAT SENSORS

In a telemedicine system, physiological sensors are provided in a toilet seat for monitoring physiological parameters of the subject, corroborate sensor data against other sensor data and notify personnel in the event of a problem or Concern. 1. A system for remote medicine , comprisinga smart toilet seat that includes at least one toilet seat sensor,at least one non-toilet seat sensor,a processor connected to the sensors,memory enabled with machine readable code defining an algorithm for identifying a trigger event based on anomalies in the data from at least one toilet seat sensor, and defining an algorithm for corroborating the trigger event from the at least one toilet seat sensor with data from at least one other toilet seat sensor or at least one non-toilet seat sensor, to define a flagging event, andnotifying one or more people about the flagging event and details about said event.2. The system of claim 1 , wherein an anomaly includes one or more of a physiological characteristic or condition of interest claim 1 , and a change in a physiological parameter.3. The system of claim 1 , wherein the at least one toilet seat sensor includes one or more of claim 1 , an electrocardiogram (ECG) for measuring the electrical activity of the heart claim 1 , a pulse oximeter or photoplethysmogram (PPG) for measuring blood oxygenation and localized pulse timing claim 1 , a ballistocardiogram (BCG) for measuring the mechanical forces associated with the cardiac cycle claim 1 , and a body weight sensor.4. The system of claim 1 , wherein the at least one non-toilet seat sensor includes one or more of an image capture device claim 1 , a microphone claim 1 , a genetic sensor claim 1 , and a drug compliance sensor.5. The system of claim 4 , wherein the image capture device includes one or more cameras mounted at different locations and operating at different ranges of the frequency spectrum.6. The system of claim 5 , wherein the image capture device includes a camera mounted in ...

AUTOMATED CCHD SCREENING AND DETECTION

Automated critical congenital heart defect (“CCHD”) screening systems and processes are described. A caregiver may be guided to use a single or dual sensor pulse oximeter to obtain pre- and post-ductal blood oxygenation measurements. A delta of the measurements indicates the possible existence or nonexistence of a CCHD. Errors in the measurements are reduced by a configurable measurement confidence threshold based on, for example, a perfusion index. Measurement data may be stored and retrieved from a remote data processing center for repeated screenings. 1. (canceled)2. A method of determining a likelihood of a critical congenital heart defect using a pulse oximeter , the method comprising:displaying, on a display of a pulse oximeter, instructions to a caregiver to position a noninvasive sensor at a first measurement site on a patient predetermined to be substantially indicative of a pre-ductal blood oxygenation level and not substantially indicative of a post-ductal blood oxygenation level, wherein the noninvasive sensor is configured to output signals responsive to attenuation of light at measurement sites on the patient to the pulse oximeter, wherein the first measurement site is on a first limb of the patient;displaying, on the display of the pulse oximeter, an indication to the caregiver of a success or failure of obtaining a measure of pre-ductal blood oxygenation level at the first measurement site;displaying, on the display of the pulse oximeter, instructions to the caregiver to position the noninvasive sensor at a second measurement site on the patient predetermined to be substantially indicative of a post-ductal blood oxygenation level and not substantially indicative of a pre-ductal blood oxygenation level, wherein the second measurement site is on a second limb of the patient, and wherein the second limb of the patient is different from the first limb of the patient;displaying, on the display of the pulse oximeter, an indication to the caregiver of a ...

MACHINE-LEARNING-BASED DENOISING OF DOPPLER ULTRASOUND BLOOD FLOW AND INTRACRANIAL PRESSURE SIGNAL

An apparatus and methods for processing monitored biosignals are provided that are particularly suited for reducing noise and artifacts in continuously monitored quasi-periodic biosignals without prior knowledge of the noise distribution. The framework trains a subspace manifold with reference signals. Subsequent signals are successively projected onto the trained manifold and adjusted based on the nearest neighbors of the state of the sample being projected as well as the state of the sample at the previous time point. A denoised or modified output is obtained with inverse mapping. The reference signals may optionally be labeled during manifold training with clinical events/variables or measurable diseases/injuries from a library of relevant labels. During reconstruction, the label of the estimated state in the manifold can be obtained from the label corresponding to the estimated state. 1. An apparatus for reducing noise in continuously monitored quasi-periodic biosignals without prior knowledge of the noise distribution , comprising:(a) a computer processor; and(b) a non-transitory computer-readable memory storing instructions executable by the computer processor; (i) acquiring a plurality of reference signals;', '(ii) forming a subspace representation of the reference signals to produce a learned manifold graph;', '(iii) iteratively projecting successive signals on the learned manifold graph; and', '(iv) reconstructing the most likely shape of the successive signal., '(c) wherein said instructions, when executed by the computer processor, perform steps comprising2. The apparatus of claim 1 , wherein said instructions when executed by the computer processor further perform steps comprising:extracting individual pulses from said plurality of reference signals;distilling at least one variable from the extracted pulses;normalizing the extracted pulses; andclustering similar normalized pulses to produce an idealized reference signal.3. The apparatus of claim 1 , ...

METHOD AND APPARATUS FOR SCORING THE RELIABILITY OF SHOCK ADVISORY DURING CARDIOPULMONARY RESUSCITATION

A method, system and device to detect and use clean ECG segments, which do not need filtering to remove artifact or CPR-induced noise, is described to provide a reliability score for the decision made by shock advisory algorithms. The method can be implemented in a system and/or device that is provided with a display for indicating to a user the relative quality of the determination of an electrotherapy analysis circuit. 18-. (canceled)9. A medical device for determining the reliability of a cardiac rhythm analysis during the performance of cardiopulmonary resuscitation (CPR) comprising:a front end operable to obtain two or more time-sequential ECG data sets comprised of a first ECG data set and a second ECG data set;an input operable to acquire two or more time-sequential CPR reference signal data sets which correspond in time to the time-sequential ECG data sets;a chest compression detector in communication with the input, operable to detect whether or not each of the ECG data sets contains CPR-related noise;a shock advisory algorithm module in communication with the input and the chest compression detector and operable to analyze and classify each of the ECG data sets as a shock advice or a no-shock advice;a reliability analyzer in communication with the chest compression detector and the shock advisory algorithm module operable to determine the reliability of the most recent ECG advice;a shock decision generator in communication with the reliability analyzer and the shock advisory algorithm module operable to generate a shock decision; andan output generator for issuing a user-perceptible indication of the shock decision and the reliability of the ECG shock advice.10. The medical device of claim 9 , wherein the medical device is a defibrillator.11. The medical device of claim 9 , wherein the input is selected from the group consisting of a thoracic impedance signal claim 9 , an accelerometer claim 9 , a force sensor claim 9 , or a compressions status signal from ...

SIMULTANEOUS PHYSIOLOGICAL SENSING AND STIMULATION WITH SATURATION DETECTION

Systems and method may be used for interfacing with a patient. Systems may include a plurality of electrodes in electrical communication with a processor. The processor may be configured to receive sense signals from electrodes and to determine the reliability of the received signal. A test tone signal comprising a test tone frequency may be applied, and the magnitude of the test tone frequency may be analyzed in the received signal. If it is determined that the magnitude of the test tone frequency is below a threshold, the system may take action, such as lowering the gain on an amplifier. Stimulation signals may be applied to the patient at a stimulation frequency simultaneously with one or both of receiving sense signals and providing the test tone signal. 129-. (canceled)30. A method of monitoring physiological activity comprising:applying, by a processor, a test tone signal to a patient via at least one test electrode, the test tone signal having a test tone frequency;receiving, by the processor, a sense signal from the patient via at least one sense electrode, wherein the received signal comprises a first component at the test tone frequency and a second component indicative of physiological activity of the patient;amplifying the received sense signal via at least one amplifier, wherein the amplified sense signal comprises a third component at the test tone frequency and a fourth component indicative of physiological activity of the patient;detecting a magnitude of the third component of the amplified sense signal at the test tone frequency; andin response to the magnitude dropping below a predetermined threshold, reducing, by the processor, the gain of the at least one amplifier.31. The method of claim 30 , further comprising:applying, by the processor, a stimulation signal to the brain via at least one stimulation electrode; anddetermining, by the processor, a change in the amplified sense signal indicative of promoted or suppressed physiological activity ...

Method For Improving Heart Rate Estimates By Combining Multiple Measurement Modalities

Systems and methods are provided for determining the frequency of a cardiovascular pulse based on a first physiological signal that is continuously available and a second physiological signal that is less available and that is more accurate or otherwise improved relative to the first signal with respect to pulse rate estimation. When the second signal is available it controls the determination of the pulse rate. When the second signal is unavailable, the first signal is used to determine the pulse rate. This can include using the first signal to estimate the pulse rate until the second signal is available, at which point the pulse rate is estimated based on the second physiological signal. Alternatively, the first signal could be used to determine a number of candidate pulse rates, and the second signal could be used to select a pulse rate from the set of candidate pulse rates. 120-: (canceled)21. A method comprising:during a first period of time, detecting a first-sensor signal from a first sensor;determining a pulse rate for the first period of time based on the first-sensor signal detected during the first period of time;during a second period of time, detecting the first-sensor signal from the first sensor and a second-sensor signal from a second sensor, wherein the second period of time is after the first period of time;determining a pulse rate for the second period of time based on the first-sensor signal detected during the second period of time and the second-sensor signal detected during the second period of time;updating the pulse rate for the first period of time based on the determined pulse rate for the second period of time; andproviding, via a user interface, an indication of the updated pulse rate for the first period of time.22. The method of claim 21 , wherein determining the pulse rate for the first period of time based on the first-sensor signal detected during the first period of time comprises:sampling the first-sensor signal during the first ...

ENHANCED NEUROPSYCHOLOGICAL ASSESSMENT WITH EYE TRACKING

Provided are methods and system for assessing a human subject's neurological and/or psychological status. The methods entail displaying visual tests to a human subject, wherein each of the visual tests includes a visual target signal, optionally with visual cue signals, for eliciting visual and, optionally, body part, movements by the subject. Following the display, the movements are then detected. The latency and/or correctness of such movements can then be used to assess the subject's neurological and/or psychological status. Also provided are methods and systems for assessing performance validity. 138.-. (canceled)39. A system comprising a processor and program code which , when executed by the processor , configures the system to conduct an assessment of the neurological and/or psychological status of a subject comprising:displaying a plurality of visual tests to a human subject, wherein each visual test comprises a visual target signal associated with a commanded eye movement and, optionally, a commanded body part movement;detecting, following the display of each visual target signal, a responsive eye movement of the subject and, optionally, a responsive body part movement of the subject; andassessing the neurological and/or psychological status of the subject based on one or more of the latency and correctness of the responsive movements with regard to the commanded movements associated with each visual test.40. The system of claim 39 , wherein the correctness of a responsive movement is determined with reference to its correlation with the visual target signal of the visual test.41. The system of claim 39 , wherein one or more of the visual tests further comprises a visual cue signal displayed prior to the visual target signal.42. The system of claim 41 , wherein the visual cue signal is selected from the group consisting of nondirectional cue signals claim 41 , directional cue signals claim 41 , misdirectional cue signals claim 41 , inhibition cue signals ...

Method, apparatus and non-transitory computer-readable recording medium for measuring photoplethysmography signals

Provided herein are methods, apparatuses, and non-transitory computer-readable recording media for measuring photoplethysmography (PPG) signals. Accurate PPG signals can be obtained even in a situation in which brightness of ambient light is not constant due to external light sources, and accuracy of a variety of biological information derivable from the PPG signals can be improved.

METHOD, APPARATUS AND NON-TRANSITORY COMPUTER-READABLE RECORDING MEDIUM FOR MEASURING PHOTOPLETHYSMOGRAPHY SIGNALS

There are provided a method, apparatus and non-transitory computer-readable recording medium for measuring photoplethysmography (PPG) signals. Accurate PPG signals can be obtained even when brightness of ambient light is not constant due to external light sources, and accuracy of a variety of biological information derivable from the PPG signals can be improved. 1. A method for measuring photoplethysmography (PPG) signals , comprising:irradiating light of a first wavelength range and light of a second wavelength range onto a body part of a user, respectively;sensing light of the first wavelength range entering through a first filter and light of the second wavelength range entering through a second filter, respectively, and measuring a first illuminance of the light of the first wavelength range entering through the first filter and a second illuminance of the light of the second wavelength range entering through the second filter, respectively; andgenerating a first PPG signal corresponding to the sensed light of the first wavelength range and a second PPG signal corresponding to the sensed light of the second wavelength range,wherein, in the irradiating step, brightness of at least one of the light of the first wavelength range and the light of the second wavelength range irradiated onto the body part of the user is adjusted such that a difference between a predetermined reference illuminance and at least one of the first and second measured illuminances is less than a predetermined level.2. The method of claim 1 , wherein claim 1 , in the irradiating step claim 1 , the brightness of at least one of the light of the first wavelength range and the light of the second wavelength range irradiated onto the body part of the user is increased when at least one of the first and second measured illuminances is less than the predetermined reference illuminance.3. The method of claim 1 , wherein claim 1 , in the generating step claim 1 , an intensity of at least one of the ...

Information processing apparatus, information processing method, and program

An information processing apparatus according to an embodiment of the present technology includes an acquisition section and a processor. The acquisition section acquires eye information regarding an eye of a user. The processor determines a first line-of-sight direction on the basis of the eye information using a first method, determines a second line-of-sight direction on the basis of the eye information using a second method that is different from the first method, calculates reliability information regarding at least one of reliability of the first line-of-sight direction or reliability of the second line-of-sight direction, and determines a line-of-sight direction of the user on the calculated reliability information.

Apparatus and Method for Adaptive Closed-loop Control of Oxygen-Hemoglobin Saturation Levels

The present invention is a method, system, and apparatus for providing automated closed-loop control of oxygen-hemoglobin saturation, SO, levels that adapts to the specific, unique, and variable needs of the individual patient in real-time. A method, system, and standalone breathable gas blending apparatus for controlling SOlevels in human patients requiring supplemental oxygen therapy, inclusive of adults, pediatrics, and neonates, are described. 1. A method for adjusting and blending inspired oxygen delivered to a patient in response to a hemoglobin oxygen saturation level measured in the patient , comprising:(a) specifying a target range of hemoglobin oxygen saturation levels through a user interface in communication with a signal and data processor (SDP);(b) specifying an initial inspired oxygen level to be delivered to the patient as determined by the care provider through the user interface;{'sub': p', '2, '(c) measuring a hemoglobin oxygen saturation level of a patient at an SOsensor;'}{'sub': p', '2, '(d) transmitting a signal with a measured hemoglobin oxygen saturation value of the patient from the SOsensor;'}{'sub': p', '2, '(e) receiving the signal from the SOsensor at the SDP;'}(f) comparing the measured hemoglobin oxygen saturation value to at least one preset patient parameter and a target rate of change of the at least one preset patient parameter using the SDP;(g) determining whether the measured hemoglobin oxygen saturation value is within the target range using the SDP;(h) incorporating the difference between the target and measured oxygen hemoglobin values into an adaptive response parameter;(i) computing the hemoglobin oxygen saturation value predicted to occur at the next measurement;(j) comparing the predicted hemoglobin oxygen saturation value to the target value and range, and predicted future values of the patient's hemoglobin saturation level;(k) if it is determined that the predicted hemoglobin oxygen saturation value is outside the ...

Method and System of Utilizing ECG Signal for Central Venous Catheter Tip Positioning

Disclosed herein are a method and a medical system for utilizing of an intravascular ECG signal for central venous catheter placement. The medical system is capable of detecting the position of a catheter tip and assessing its location relative to the cavoatrial junction. The detection and assessment are performed by a multiscale analysis of the complexity of the intravascular signal data points. 1. (canceled)2. A medical system for placement of a central venous catheter comprising:a placement unit including an electrode usable to acquire intravascular ECG (ivECG) signal data;a multiscale complexity analysis module including software programmed for processing the ivECG signal data acquired by the electrode; anda visualization device configured to provide a visual indication of a proximity of the central venous catheter to a part of a patient's body.3. The medical system according to claim 2 , wherein the part of the patient's body is a cavoatrial junction of the patient's body.4. The medical system according to claim 2 , wherein the software of the multiscale complexity analysis module is programmed to determine at least one PxI value based on the ivECG signal data acquired by the electrode.5. The medical system according to claim 4 , wherein the visualization device is configured to provide a user with the visual indication of the proximity of the central venous catheter to the part of the patient's body based on a comparison of the at least one PxI value with a proximity threshold.6. The medical system according to claim 2 , wherein the electrode is positioned at a tip of the central venous catheter.7. The medical system according to claim 6 , wherein the electrode is attached to the central venous catheter.8. A medical system for placement of an endovascular device comprising:an electrode usable to acquire intravascular ECG (ivECG) signal data;a multiscale complexity analysis module including software, the software comprising instructions to determine at least ...

SENSOR PLACEMENT ERROR DETECTION AND CORRECTION

A method of performing sensor placement error detection and correction for a system for tracking human motion includes 2. The method according to claim 1 , wherein the reasons are hierarchically ranked.3. The method according to claim 1 , wherein it is checked claim 1 , which reasons have already been presented.4. The method according to claim 1 , wherein it is checked claim 1 , whether still reasons are left.5. The method according to claim 4 , wherein if no reasons are left claim 4 , the method routine is ended.6. The method according to claim 4 , wherein if reasons are left claim 4 , the hierarchically top ranked reason is selected and presented to the user.7. The method according to claim 1 , wherein a feedback from the user regarding fulfillment of the present unmet condition is received.8. A system for tracking human motion comprising:at least one sensor unit,at least one sensor holder,an analyzing module, configured and arranged such that it can be analyzed, whether there is a condition for correct sensor unit placement not met,a presenting module, comprising a storage element, the storage element being equipped with potential reasons for the incorrect sensor unit placement, wherein the presenting module is further configured and arranged such that in case of detecting an unmet condition out of the storage element a least of potential reasons for the incorrect sensor unit placement is provided, and a selection module; remove, by means of the selection module, the possible reasons for incorrect sensor placement already presented to a user, and', 'select, by the selection module, the one of the reasons and present it to a user., 'wherein the presenting module is configured to'}9. The system according to claim 8 , wherein the storage element is configured such that the reasons are stored within the storage element in a hierarchical ranking.10. The system according to claim 8 , wherein the selection module is configured such that the selection module is ...

Method and System for Enhancing Monitoring Glucose

Methods and systems for enhancing glucose monitoring are disclosed that allow for more precise control of the glucose level by taking into account new control parameters. The disclosed methods include obtaining an initial CGM value (CGM) from a CGM sensor, obtaining a set of parameters from a wearable device, calculating an error (E) in the initial CGM value (CGM) using a regression algorithm based upon the initial CGM value and the obtained set of parameters, and calculating an enhanced CGM value (eCGM) according to the formula eCGM=CGM−E. The error (E) is calculated according to the formula: E=θ*p, wherein E is the calculated error, θ represents the data obtained from the wearable device after removing a baseline value of each wearable, and p represents regression parameters based upon an error value obtained in a training population. 1. A method for enhancing monitoring glucose , the method comprising:obtaining an initial CGM value (CGM) from a CGM sensor;obtaining a set of parameters, from a wearable device; {'br': None, 'i': 'E=θ*p,'}, 'calculating an error (E) in the initial CGM value (CGM), by using a regression algorithm based upon the initial CGM value and the obtained set of parameters, according to the formulawherein E is the calculated error, θ represents the data obtained from the wearable device, after removing a baseline value of each wearable, and p represent regression parameters based upon an error value obtained in a training population; and {'br': None, 'i': 'E.', 'eCGM=CGM−'}, 'calculating an enhanced CGM value (eCGM), according to the formula2. The method of claim 1 , wherein the regression parameters (p) are obtained by means of a calibration process in which data obtained for a training population is used.3. The method of claim 1 , wherein the wearable parameters are at least one of metabolic equivalent or a skin temperature.4. The method of claim 1 , further comprising a step of calculating an amount of insulin needed according to the ...

Robust fractional saturation determination

The present disclosure describes the derivation and measurement of a fractional oxygen saturation measurement. In one embodiment, a system includes an optical sensor and a processor. The optical sensor can emit light of multiple wavelengths directed at a measurement site of tissue of a patient, detect the light after attenuation by the tissue, and produce a signal representative of the detected light after attenuation. The processor can receive the signal representative of the detected light after attenuation and determine, using the signal, a fractional oxygen saturation measurement based on two or more different measures of fractional oxygen saturation.

SYSTEMS AND METHODS FOR ANALYSIS OF SLEEP DISORDERED BREATHING EVENTS

The present disclosure provides a method of sleep assessment. In accordance with aspects of the present disclosure, a method includes accessing oxygen saturation data including oxygen saturation measurements for a person over a time period, determining disordered breathing events for the person over the time period based on the oxygen saturation data, accessing cardiopulmonary coupling data for the person during sleep, wherein the cardiopulmonary coupling data is correlated in time with the oxygen saturation data over the time period, and determining a type of cardiopulmonary coupling event for each of the disordered breathing events based on the cardiopulmonary coupling data corresponding in time to the disordered breathing events. 1. A method of sleep assessment , comprising:accessing oxygen saturation data including oxygen saturation measurements for a person over a time period;determining disordered breathing events for the person over the time period based on the oxygen saturation data;accessing cardiopulmonary coupling data for the person during sleep, wherein the cardiopulmonary coupling data is correlated in time with the oxygen saturation data over the time period; anddetermining a type of cardiopulmonary coupling event for each of the disordered breathing events based on the cardiopulmonary coupling data corresponding in time to the disordered breathing events.2. The method according to claim 1 , further comprising determining claim 1 , based on the oxygen saturation data claim 1 , that the disordered breathing events are sleep disordered breathing events.3. The method according to claim 1 , wherein determining the disordered breathing events includes:identifying a start of a potential disordered breathing event by a decrease between a first oxygen saturation measurement and a second oxygen saturation measurement in the oxygen saturation data, wherein the second oxygen saturation measurement is temporally after the first oxygen saturation measurement; and ...

SYSTEMS AND METHODS OF IV INFILTRATION DETECTION

As an IV infiltration occurs and fluid leaks into surrounding tissues, several physiological changes are expected locally. The systems and methods described herein provide a scalable automated IV infiltration detection device to provide medical staff an early warning of a possible infiltration such that they can respond accordingly. The systems and methods capture the physiological state of the user at or around a peripheral catheter insertion site by incorporating one or more modalities of wearable sensing, processing the data collected from these wearable sensors, detecting the presence of extravascular fluid, and providing an indication to a medical professional. 1. A sensor system for automated detection of IV infiltration remote from a patient , the patient untethered from a processor physically separated from the patient , the sensor system comprising:a physiological state sensor having wireless communication capability to communicate with the off-body processor; andan electrical bioimpedance sensor (EBI) having wireless communication capability to communicate with the processor,wherein readings of the EBI sensor in a first predetermined range are indicative of IV infiltration and wherein readings of the physiological state sensor in a second predetermined range in a time frame relative to timing of a reading of the EBI sensor are at least one of indicative of the reading of the EBI sensor being questionable and information about underlying physiological changes due to IV infiltration.2. The sensor system of claim 1 , wherein the physiological state sensor is an on-body sensor and the EBI sensor is an on-body sensor.3. The sensor system of claim 1 , wherein the physiological state sensor and the EBI sensor are proximal to one another on the body of the patient.4. The sensor system of claim 1 , wherein the physiological state sensor and the EBI sensor are co-located at or around a peripheral catheter insertion site on the patient's body.5. The sensor system of ...

Electronic device for recommending contents

An electronic device in various embodiments may include: a communication circuit configured to communicate with an external electronic device; a memory configured to store user reaction data indicating reactions to contents for users and biostatistic data for users; and a processor connected to the communication circuit and the memory, wherein the processor is configured to: calculate preference values for contents, to which users have reacted, for users using the user reaction data; predict preference values for contents, which have not been exposed to users, for users using the calculated preference values; generate profiles related to states or activities for users using the biostatistic data; calculate reliability values for the generated profiles; calculate relevance values indicating degrees of relevance between profile types and contents based on the calculated preference values, the predicted preference values, and the calculated reliability values; select, from among contents which have not been exposed to a user selected from among the users, a content to be recommended to the selected user based on the predicted preference values; select, as a profile for generation of a recommendation reason, at least one of profiles of the selected user based on reliability values for the profiles of the selected user and relevance values between the recommended content and the profile types; and control the communication circuit to transmit the selected profile and the recommended content to an external electronic device of the selected user.

APPLICATION OF ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY IN SENSOR SYSTEMS, DEVICES, AND RELATED METHODS

A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters. 1. A method of calculating a single , fused sensor glucose value based on respective glucose measurement signals of a plurality of redundant sensing electrodes , comprising:performing respective electrochemical impedance spectroscopy (EIS) procedures for each of the plurality of redundant sensing electrodes to obtain values of at least one impedance-based parameter for each said sensing electrode;measuring the electrode current (Isig) for each of the plurality of redundant sensing electrodes;calibrating each of the measured Isigs by using a blood glucose (BG) value to obtain respective calibrated sensor glucose values; calculating a first similarity index to determine an amount of divergence between respective Isigs of at least a first one and a second one of said plurality of redundant sensing electrodes;', 'calculating a second similarity index to determine an amount of divergence between respective values of the at least one impedance-based parameter for said at least first one and ...

METHODS FOR DETECTION AND CONFIDENCE EVALUATION OF VITAL SIGN SIGNAL

In a method for detection of vital sign signal, a variation detection module is configured to determine whether there is a living body in an image captured by an image capture module, next, a beam direction of a vital sign sensing system is directed toward the living body to detect vital sign signal of the living body, and a compute module is configured to compute eigenvalue and confidence of the vital sign signal so as to reconfirm whether the determined living body in the image is a living body having vital signs. 1. A method for detection of a vital sign signal , comprising:capturing an image by using an image capture module;determining whether there is a living body captured in the image by using a variation detection module;changing a beam direction of a vital sign sensing system toward the living body;detecting a vital sign signal of the living body by using the vital sign sensing system;receiving the vital sign signal from the vital sign sensing system and computing a eigenvalue of the vital sign signal by using a compute module; andevaluating a confidence of the vital sign signal according to the eigenvalue of the vital sign signal by using the compute module.2. The method in accordance with claim 1 , wherein the image capture module is an optical camera claim 1 , an infrared camera claim 1 , a radar claim 1 , an ultrasonic imaging system or a thermal imaging camera.3. The method in accordance with further comprising a step of transforming an image coordinate of the image into a real coordinate by using the variation detection module before the step of changing the beam direction of the vital sign sensing system.4. The method in accordance with claim 1 , wherein the vital sign sensing system includes an actuator configured to change the beam direction of the vital sign sensing system.5. The method in accordance with claim 1 , wherein the vital sign sensing system includes a plurality of antennas configured to radiate a beam to change the beam direction ...

SYSTEMS AND METHODS FOR CARDIAC TRIGGERING OF AN IMAGING SYSTEM

Methods and systems are provided for cardiac triggering of an imaging system. a method for an imaging system comprises acquiring, during a scan of a subject, an electrical signal indicating a periodic physiological motion of an organ of the subject, inputting a sample of the electrical signal into a trained neural network to detect whether a peak is present in the sample, triggering acquisition of image data responsive to detecting the peak in the sample, and not triggering the acquisition of image data responsive to not detecting the peak in the sample. In this way, the timing of data acquisition may be optimally and robustly synchronized with a cardiac cycle. 1. A method for an imaging system , comprising:acquiring, during a scan of a subject, an electrical signal indicating a periodic physiological motion of an organ of the subject;inputting a sample of the electrical signal into a trained neural network to detect whether a peak is present in the sample;triggering acquisition of image data responsive to detecting the peak in the sample; andnot triggering the acquisition of image data responsive to not detecting the peak in the sample.2. The method of claim 1 , further comprising pre-processing the electrical signal to generate the sample of the electrical signal claim 1 , wherein pre-processing the electrical signal comprises acquiring a plurality of discrete measurements of the electrical signal over time for a given duration to generate the sample.3. The method of claim 2 , wherein pre-processing the electrical signal further comprises converting the electrical signal from digital values to millivolts.4. The method of claim 2 , wherein the plurality of discrete measurements of the electrical signal over time for the given duration comprises a raw sample claim 2 , and wherein pre-processing the electrical signal further comprises applying one or more passband filters to the raw sample to generate one or more filtered samples claim 2 , wherein the sample ...

DEVICE, SYSTEM AND METHOD FOR NONINVASIVELY MONITORING PHYSIOLOGICAL PARAMETERS

A system for monitoring vital signs, configured to be used in conjunction with a computerized mobile device, the system including: a cover sensor assembly adapted to be operably engaged with the computerized mobile device, the cover sensor assembly having integrated therein at least one physiological sensor; a physiological data acquisition module configured to generate a physiological parameter measurement descriptive of a physical stimulus received by the at least one physiological sensor; and a validation module configured to control a validity status of the physiological parameter measurement. 1. A system for monitoring vital signs , configured to be used in conjunction with a computerized mobile device , the system comprising:a cover sensor assembly adapted to be operably engaged with the computerized mobile device, said cover sensor assembly having integrated therein at least one physiological sensor;a physiological data acquisition module configured to generate a physiological parameter measurement descriptive of a physical stimulus received by said at least one physiological sensor anda validation module configured to control a validity status of said physiological parameter measurement,2. The system of claim 1 , further comprising at least one validation sensor claim 1 , positioned so as to be used in conjunction with said at least one physiological sensor and configured to provide validation data to said validation module to determine said validity status of said physiological parameter Measurement.3. The system of claim 2 , wherein said at least one validation sensor configured to sense Whether said at least one physiological sensor is positioned to receive said physical stimulus in a valid manner.4. The system of claim 3 , wherein said at least one physiological sensor is a photoplethysmograph sensor and said at least one validation sensor is selected from a group of sensors including: a pressure sensor claim 3 , a position sensor claim 3 , a capacitance ...

DETECTION OF VALID SIGNALS VERSUS ARTIFACTS IN A MULTICHANNEL MAPPING SYSTEM

A system and associated method is disclosed for determining whether signal is valid. The system comprises an electrode apparatus comprising a plurality of electrodes configured to be located proximate tissue of a patient. A display apparatus comprising a graphical user interface, wherein the graphical user interface is configured to present information to a user. A computing apparatus coupled to the electrode apparatus and display apparatus, wherein the computing apparatus is configured to determine whether a signal acquired from a channel associated with an electrode from the plurality of electrodes is valid and sufficiently strong by i) calculating a first derivative of the signal; ii) determining a minimum and maximum derivative from the first derivative; iii) determining whether signs of the minimum and maximum derivative are different; and in response to determining whether the signs of the minimum and maximum derivative are different, displaying on a display apparatus whether the signal is valid. 1. A system for use in monitoring cardiac signals comprising:an electrode apparatus comprising a plurality of electrodes configured to be located proximate tissue of a patient;display apparatus comprising a graphical user interface, wherein the graphical user interface is configured to present information to a user; i) calculating a first derivative of the signal;', 'ii) determining a minimum and maximum of the first derivative;', 'iii) determining whether signs of the minimum and maximum of the first derivative are different; and, 'computing apparatus coupled to the electrode apparatus and display apparatus, wherein the computing apparatus is configured to determine whether a signal acquired from a channel associated with an electrode from the plurality of electrodes is valid and sufficiently strong byin response to determining whether the signs of the minimum and maximum of the first derivative are different, displaying on the graphical user interface whether the ...

BIOSIGNAL PROCESSING APPARATUS AND METHOD

A biosignal processing apparatus includes a communication interface configured to receive a biosignal, and a processor configured to set a target interval of the biosignal, calculate a quality metric corresponding to the target interval based on a target component that is a frequency component of the target interval corresponding to a set value and a non-target component that is a frequency component of the target interval not corresponding to the set value, and estimate a quality of the biosignal based on the quality metric. 1. A biosignal processing apparatus comprising:a communication interface configured to receive a biosignal; anda processor configured to set a target interval of the biosignal, calculate a quality metric corresponding to the target interval based on a target component that is a frequency component of the target interval corresponding to a set value and a non-target component that is a frequency component of the target interval not corresponding to the set value, and estimate a quality of the biosignal based on the quality metric.2. The apparatus of claim 1 , wherein the processor is further configured to convert the target interval to a frequency domain signal claim 1 , and define claim 1 , as the target component claim 1 , a frequency component that is an integral multiple of the set value among frequency components of the frequency domain signal.3. The apparatus of claim 1 , wherein the processor is further configured to extract from the target interval a first number of signals corresponding to the target component claim 1 , and extract from the target interval a second number of signals corresponding to the non-target component; andthe second number is defined based on the first number and the set value.4. The apparatus of claim 3 , wherein the processor is further configured to calculate the quality metric using an electric power of the extracted first number of signals and an electric power of the extracted second number of signals.5. The ...

APPARATUS AND METHOD FOR ENHANCING ACCURACY OF A CONTACTLESS BODY TEMPERATURE MEASUREMENT

An electronic device for enhancing accuracy of a contactless body temperature measurement is provided. The electronic device includes a camera module for determining whether an image of an object is in focus, a temperature sensor for measuring a temperature of the object, and a processor for determining, as a temperature of the object, a temperature output from the temperature sensor corresponding to a focus matching time as a result of determining whether the image of the object is in focus. 1. An electronic device for enhancing accuracy of a contactless body temperature measurement , the electronic device comprising:a camera module for determining whether an image of an object is in focus;a temperature sensor for measuring a temperature of the object; anda processor for determining, as a temperature of the object, a temperature output from the temperature sensor corresponding to a focus matching time as a result of determining whether the image of the object is in focus.2. The electronic device of claim 1 , wherein the image of the object is an image of at least one of a portion of a forehead of a human being and a portion from behind an ear lobe of the human being.3. The electronic device of claim 1 , further comprising a display that is in operable communication with the processor for displaying the image of the object and a measurement result including the determined temperature of the object.4. The electronic device of claim 1 , further comprising a communication interface for connecting the electronic device to another electronic device via a short-range wireless communication scheme and transmitting a measurement result including the determined temperature of the object to the another electronic device for displaying the the measurement result including the determined temperature of the object on a screen of the another electronic device.5. The electronic device of claim 1 , wherein the camera module and the temperature sensor are activated when an ...

Health diagnostic systems and methods

A health monitoring system, and methods of use and manufacture thereof are disclosed. The health monitoring system may include a computing system and a diagnostic test coupled to a diaper. The diagnostic test may include one or more sensors configured to produce a visual indication of one or more analytes contained in a sample produced by a subject. The diagnostic test may include a machine-readable code. The computing system may be configured to read the machine-readable code to allow an application running on the computing system to automatically perform at least one task related to a production of a data point based on the visual indication. The health monitoring system may aid in identifying a potential abnormal health condition of the subject by providing automatic longitudinal analysis of analytes contained in samples produced by the subject over a period of time.

APPARATUS AND METHOD FOR DETERMINING VALIDITY OF BIOLOGICAL DATA

A method that includes acquiring a first biological data of a user from a measuring device and determining whether the acquired first biological data is within a valid data range, such that the valid data range includes at least one valid section, and a validity time period is set for each section of the at least one valid section. The method further includes transmitting the first biological data to a terminal when the acquired first biological data is within the valid data range. 1. A data transmission method , comprising:acquiring a first biological data of a user from a measuring device;determining whether the acquired first biological data is within a valid data range, wherein the valid data range includes at least one valid section, and a validity time period is set for each section of the at least one valid section; andtransmitting the first biological data to a terminal when the acquired first biological data is within the valid data range.2. The method of claim 1 , wherein the biological data is at least one of body weight claim 1 , height claim 1 , blood glucose level claim 1 , blood pressure claim 1 , or body temperature.3. The method of claim 1 , further comprising:updating the validity time period set for at least one valid section of the at least one valid section.4. The method of claim 1 , further comprising:outputting a message requesting communication with the terminal when the first biological data is not included within the valid data range.5. The method of claim 1 , further comprising:updating the valid data range based on the first biological data when information, indicating that the first biological data is valid, is received from the terminal, wherein the updating occurs despite the first biological data being not included within the valid data range.6. The method of claim 5 , wherein the updating comprises adjusting the valid data range to include a new valid section including the first biological data claim 5 , and setting a validity time ...

METHOD OF DETECTING AND PREDICTING OVULATION AND THE PERIOD OF FERTILITY

Methods of detecting and predicting ovulation and a period of fertility include determining a series of measures indicative of the basal body temperature of a female human user to identify a temperature change event. The method includes obtaining, within a first 24 hour period, a plurality of first readings of the temperature of the female human user at intervals over a first extended period of at least an hour. The plurality of first readings are then processed to determine at least one first representative temperature reading representative of the basal body temperature of the user for the first extended period and the at least one first representative temperature reading is stored. The method is repeated for at least second and third 24 hour periods and the representative temperature readings are provided for analysis to identify a temperature change event for the female human user. 1. A user terminal comprising:a temperature measuring device for taking multiple body temperature readings from a female mammal during multiple extended periods:a memory for storing said temperature readings;means for communicating the multiple body temperature readings, or a derivative thereof, stored in the memory to a remote data processing device;means for receiving information relevant to the fertility of the female mammal from a remote computer file server; anda signalling device to provide said information relevant to the fertility of the female mammal to a user.2. A user terminal according to claim 1 , wherein the temperature measuring device comprises a wearable claim 1 , removable temperature sensor.3. A user terminal according to wherein the temperature measuring device comprises an intravaginal temperature measuring device.4. A user terminal according to wherein the remote data processing device comprises a device associated with the user.5. A user terminal according to wherein the remote data processing device comprises a display for providing the information relevant to ...

SYSTEMS AND METHODS FOR DETERMINING ENGAGEMENT OF A PORTABLE DEVICE

A portable device is provided having a motion sensor and an engagement sensor. A determination may be made whether the portable device is engaged with the platform. The data being output by the sensor may be used accordingly. 1. A method for determining engagement of a portable device with a platform , comprising:obtaining motion sensor data for the portable device;obtaining engagement sensor data for the portable device; anddetermining the portable device is exhibiting motion with respect to the platform when the engagement sensor data exceeds an engagement threshold, wherein the engagement threshold is based at least in part on the motion sensor data.2. The method of claim 1 , wherein the motion sensor data comprises accelerometer data.3. The method of claim 1 , wherein the motion sensor data comprises gyroscope data.4. The method of claim 1 , wherein the engagement sensor is selected from the group consisting of a proximity sensor and a distance sensor.5. The method of claim 1 , wherein the engagement sensor comprises a light sensor.6. The method of claim 1 , wherein the engagement threshold is based at least in part on a norm of the motion sensor data over a window of sequential samples.7. The method of claim 6 , wherein the engagement threshold is positively correlated with the norm of the motion sensor data.8. The method of claim 6 , further comprising adjusting a size of the window of sequential samples.9. The method of claim 8 , wherein the size of the window of sequential samples is positively correlated with an amount of motion indicated by the motion sensor data.10. The method of claim 1 , wherein the portable device comprises a health sensor and wherein the platform is a user.11. The method of claim 10 , wherein the health sensor comprises a photoplethysmograph sensor claim 10 , further comprising determining validity for photoplethysmograph sensor data based at least in part on whether the portable device is exhibiting motion with respect to the user.12 ...

PULSE OXIMETER ACCESS APPARATUS AND METHOD

Access is provided to certain pulse oximetry systems utilizing a keyed sensor and a corresponding locked sensor port of a restricted access monitor. In such systems, the keyed sensor has a key comprising a memory element, and the monitor has a memory reader associated with the sensor port. The monitor is configured to function only when the key is in communications with the locked sensor port, and the memory reader is able to retrieve predetermined data from the memory element. The monitor is accessed by providing the key separate from the keyed sensor, integrating the key into an adapter cable, and connecting the adapter cable between the sensor port and an unkeyed sensor so that the monitor functions with the unkeyed sensor. 110-. (canceled)11. A method of assembling a sensor apparatus that includes a noninvasive optical sensor and a memory device , the memory device storing access information usable to unlock otherwise unavailable processing by a patient monitor so that the patient monitor processes a signal output by the noninvasive optical sensor to determine a physiological parameter of a patient monitored by the noninvasive optical sensor , the method comprising:acquiring a first sensor apparatus comprising a first noninvasive optical sensor and a memory device, the first noninvasive optical sensor comprising a first detector configured to output a first signal responsive to attenuation of light by tissue of a patient, the memory device storing access information usable to unlock otherwise unavailable processing of the first signal by a patient monitor, the patient monitor being configured to lock processing of the first signal by the patient monitor unless the access information is received by the patient monitor;removing the memory device from the first sensor apparatus so that electrical communication between the memory device and the first sensor apparatus is severed; andsubsequent to said removing the memory device from the first sensor apparatus, ...

Systems and methods for processing sensor data

Systems and methods for processing sensor data are provided. In some embodiments, systems and methods are provided for calibration of a continuous analyte sensor. In some embodiments, systems and methods are provided for classification of a level of noise on a sensor signal. In some embodiments, systems and methods are provided for determining a rate of change for analyte concentration based on a continuous sensor signal. In some embodiments, systems and methods for alerting or alarming a patient based on prediction of glucose concentration are provided.

APPLICATION OF ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY IN SENSOR SYSTEMS, DEVICES, AND RELATED METHODS

A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters. 16-. (canceled)7. A method for detection of sensitivity loss for a working electrode of a sensor , the method comprising:accessing, by a microprocessor, multiple sets of impedance related data for the working electrode over time, wherein an electrochemical impedance spectroscopy (EIS) procedure is performed to generate the multiple sets of impedance related data, and each of the multiple sets of impedance related data includes data for at least one impedance-related parameter that is substantially glucose-independent;based on multiple sets of impedance related data, calculating, by the microprocessor, real impedance values at 0.105 Hz and voltages at the working electrode;determining, by the microprocessor, based on the real impedance values and voltages over time, that the working electrode is experiencing an oxygen deficiency-led loss of sensitivity based on the real impedance values becoming more positive over time and the voltages reaching a rail voltage; andbased on the ...

MONITORING PHYSIOLOGICAL PARAMETERS

A method for monitoring physiological parameters associated with a subject using a hand held device is described herein. In an implementation, the method includes obtaining a plurality of sample photoplethysmographic (PPG) features associated with a sample subject, from a video of a body part of the sample subject. From among the plurality of sample PPG features, at least one relevant sample PPG feature associated with the physiological parameter, is selected based on a ground truth value of the physiological parameter for the subject. Further, based on the at least one relevant sample PPG feature and the ground truth value of the physiological parameter, a mathematical model indicative of a correlation between the relevant sample PPG feature and the physiological parameter, is determined. The mathematical model can be deployed for monitoring the physiological parameter in real time. 1. A method for monitoring a physiological parameter associated with a subject using a hand held device , the method comprising:obtaining, by a processor, a plurality of sample photoplethysmographic (PPG) features associated with a sample subject, from a video of a body part of the sample subject;selecting, by the processor, from among the plurality of sample PPG features, at least one relevant sample PPG feature associated with the physiological parameter, based on a ground truth value of the physiological parameter for the sample subject; anddetermining, by the processor, based on the at least one relevant sample PPG feature and the ground truth value of the physiological parameter, a mathematical model indicative of a correlation between the at least one relevant sample PPG feature and the physiological parameter, wherein the mathematical model is deployed for monitoring the physiological parameter in real time.2. The method as claimed in claim 1 , wherein the obtaining the plurality of sample PPG features comprises extracting the plurality of Sample PPG features from the video in ...

REAL-TIME ASSESSMENT OF REJECTION FILTERS DURING CARDIAC MAPPING

A system includes a display and a processor. The processor is configured to (a) receive multiple electrophysiological (EP) signals acquired by multiple electrodes of a multi-electrode catheter that are in contact with tissue of a cardiac chamber, (b) reject one or more of the EP signals using a set of rejection criteria, and further process the EP signals that are not rejected, and (c) visualize to a user, on the display, (i) a current setting of the rejection criteria, and (ii) a rejection effectiveness of each of the rejection criteria at the current setting. 1. A cardiac diagnostic and therapeutic system , comprising:a display; and{'claim-text': ['receive multiple electrophysiological (EP) signals acquired by multiple electrodes of a multi-electrode catheter that are in contact with tissue of a cardiac chamber;', 'reject one or more of the EP signals using a set of rejection criteria, and further process the EP signals that are not rejected; and', 'visualize to a user, on the display, (i) a current setting of the rejection criteria, and (ii) a rejection effectiveness of each of the rejection criteria at the current setting.'], '#text': 'a processor, configured to:'}2. The system according to claim 1 , and comprising an input device claim 1 , wherein the processor is configured to receive claim 1 , via the input device claim 1 , user input that reconfigures the setting of one or more of the rejection criteria in response to the visualized rejection effectiveness.3. The system according to claim 1 , wherein the processor is configured to visualize the rejection effectiveness by plotting at least some of the EP signals claim 1 , and mark a rejected EP signal with a mark indicative of a rejection criterion used for rejecting the EP signal.4. The system according to claim 1 , wherein the processor is configured to visualize the rejection effectiveness by graphically illustrating the multiple electrodes of the multi-electrode catheter claim 1 , and claim 1 , for a ...