СПОСОБЫ, СИСТЕМА И УСТРОЙСТВО ДЛЯ ОБНАРУЖЕНИЯ, ДИАГНОСТИКИ И ЛЕЧЕНИЯ НАРУШЕНИЙ БИОЛОГИЧЕСКОГО РИТМА

Изобретение относится к медицинской технике. Представлена система восстановления информации от сердца, представляющей сложное нарушение ритма, связанное с сердцем пациента, для указания источника нарушения сердечного ритма. Сложное нарушение ритма может подвергаться лечению при помощи воздействия энергией для изменения источника нарушения ритма. Изобретение позволяет использовать сигналы с низкой достоверностью для локализации причин нарушений сердечного ритма. 20 з.п. ф-лы, 25 ил.

АЛЬТЕРНАТИВНОЕ РЕШЕНИЕ ДЛЯ НЕОПРЕДЕЛЕННЫХ ОБЛАСТЕЙ В ИЗОБРАЖЕНИЯХ MRCAT

Изобретение относится к области медицины. Система обработки для вычисления альтернативной карты (84) распределения электронной плотности исследуемого объема содержит систему (30) обработки, выполненную с возможностью вычисления первой карты (80) распределения электронной плотности с использованием множества данных визуализации, вычисления второй карты (82) распределения электронной плотности, при этом вторая карта (82) распределения электронной плотности является упрощенной версией первой карты (80) распределения электронной плотности, вычисления альтернативной карты (84) распределения электронной плотности с использованием первой карты (80) распределения электронной плотности и второй карты (82) распределения электронной плотности, при этом система (30) обработки выполнена с возможностью замены в одной или более зонах (90) артефактов первой карты (80) распределения электронной плотности второй картой (82) распределения электронной плотности с получением альтернативной карты (84) распределения ...

СИСТЕМА ДЛЯ ИЗМЕРЕНИЯ ПОКАЗАТЕЛЕЙ ЖИЗНЕДЕЯТЕЛЬНОСТИ С ИСПОЛЬЗОВАНИЕМ КАМЕРЫ

Группа изобретений относится к медицинской технике, а именно к измерению показателей жизнедеятельности, таких как частота дыхательных движений или частота сердечных сокращений. Система содержит блок формирования изображений для получения видеоданных субъекта, маркер, который может быть прикреплен к телу субъекта и содержит машинно-считываемый графический шаблон, содержащий кодированные данные, блок обработки изображений для обнаружения маркера в видеоданных и для определения кодированных данных из графического шаблона, и блок анализа, выполненный с возможностью извлечения в зависимости от кодированных данных параметра показателя жизнедеятельности, связанного с показателем жизнедеятельности субъекта, из видеоданных и определения показателя жизнедеятельности из параметра показателя жизнедеятельности. Устройство для определения показателя жизнедеятельности субъекта входит в состав системы и предназначено для выполнения способа определения показателя жизнедеятельности субъекта. Машиночитаемый ...

УСТРОЙСТВО И СПОСОБ ДЛЯ ПОЛУЧЕНИЯ ИНФОРМАЦИИ О ЖИЗНЕННО ВАЖНЫХ ПОКАЗАТЕЛЯХ ЖИВОГО СУЩЕСТВА

Группа изобретений относится к устройству и способу для получения информации о жизненно важных показателях живого существа. Устройство включает в себя блок обнаружения для приема света по меньшей мере в одном интервале длин волн, отраженного по меньшей мере от интересующей области живого существа, а также для генерирования входного сигнала из принятого света, обрабатывающий блок для обработки входного сигнала и извлечения информации о жизненно важных показателях упомянутого живого существа из упомянутого входного сигнала при помощи дистанционной фотоплетизмографии, и блок освещения для освещения по меньшей мере упомянутой интересующей области во время интервалов освещения, причем упомянутый свет во время упомянутых интервалов освещения является доминирующим над окружающим светом по меньшей мере в том диапазоне длин волн, в котором блок обнаружения принимает свет и таким образом оптимизируется для извлечения информации о жизненно важных показателях из входного сигнала, сгенерированного при ...

СИСТЕМА И СПОСОБ ДЛЯ ПРЕОБРАЗОВАНИЯ ВХОДНОГО СИГНАЛА В ВЫХОДНОЙ СИГНАЛ

Изобретение относится к системе и к способу для обработки данных, полученных из входного сигнала, содержащего физиологическую информацию. Технический результат - эффективное определение состояния человека. Система содержит средство обнаружения для обнаружения, по меньшей мере, одного отличительного признака жизненных функций во входном сигнале и средство преобразования для создания выходного сигнала посредством модификации входного сигнала в зависимости от обнаруженного отличительного признака жизненных функций. Выходной сигнал содержит искусственный отличительный признак, по меньшей мере, частично заменяющий соответствующий отличительный признак жизненных функций из, по меньшей мере, одного отличительного признака жизненных функций во входном сигнале. В одном варианте осуществления система дополнительно содержит сенсорное средство для обнаружения видимого электромагнитного излучения в пределах, по меньшей мере, одного конкретного диапазона длин волн. 3 н. и 7 з.п. ф-лы, 7 ил.

УСТРОЙСТВО МОНИТОРИНГА СЕРДЕЧНЫХ СОКРАЩЕНИЙ

Группа изобретений относится к медицинской технике. Способ мониторинга сердечных сокращений пользователя осуществляется с помощью устройства (100) мониторинга сердечных сокращений. Устройство содержит основной датчик (110) для измерения частоты сердечных сокращений пользователя, вспомогательный датчик (120) для измерения одного физиологического показателя, блок (160) управления питанием для управления работой основного датчика (110) на основании информации (126), полученной от вспомогательного датчика (120), блок (133) модели для оценки частоты сердечных сокращений пользователя на основании модели, которая хранится в блоке (133) модели, и информации (126), полученной от вспомогательного датчика (120). Основной датчик (110) имеет первый уровень потребления энергии. Вспомогательный датчик (120) имеет второй уровень потребления энергии, который ниже первого уровня потребления энергии. Блок (133) модели соединен с блоком (160) управления питанием с помощью контура обратной связи. Блок (160) ...

УСТРОЙСТВО ОПРЕДЕЛЕНИЯ СВОЙСТВА ТКАНИ

... 1. Устройство определения свойства ткани для совместной работы с оптическим измерительным устройством для определения свойства ткани, причем ткань (6) содержит эпителий (15) и строму (14) и оптическое измерительное устройство (2) содержит:- блок (2, 7, 8, 9) обеспечения света для обеспечения света (11, 12, 13), освещающего ткань (6), и- блок (4, 10) обнаружения света для обнаружения света (11, 12, 13) от ткани (6), в котором блок (3, 7, 8, 9) обеспечения света и блок (4, 10) обнаружения света выполнены с возможностью формирования первого сигнала, индицирующего свет (11), вызванный влиянием области (R1) эпителия ткани (6), содержащей эпителий (15), второго сигнала, индицирующего свет (12), вызванный влиянием граничной области (R2) ткани (6), содержащей границу между эпителием (15) и стромой (14), и третьего сигнала, индицирующего свет (13), вызванный влиянием области (R3) стромы ткани (6), содержащей строму (14),в котором устройство (16) определения свойства ткани выполнено с возможностью ...

СПОСОБ И АППАРАТ ДЛЯ ОПРЕДЕЛЕНИЯ РИСКА ПОКИДАНИЯ ПАЦИЕНТОМ БЕЗОПАСНОЙ ОБЛАСТИ

АНСАМБЛЬ КЛАССИФИКАТОРОВ ДЛЯ ОБНАРУЖЕНИЯ АНОРМАЛЬНЫХ СЕРДЕЧНЫХ ТОНОВ

АВТОМАТИЗИРОВАННЫЕ АНАЛИЗ И РАСШИФРОВКА СПИРОГРАММ

... 1. Способ оценки функции легких субъекта, причем упомянутый способ реализуется в диагностическом устройстве, выполненном с возможностью исполнения одного или более компьютерных программных модулей, и упомянутый способ содержит этапы, на которых:принимают выдыхаемый поток воздуха из дыхательных путей субъекта при выдохе субъекта;измеряют объем выдоха при выдохе субъекта по принятому выдыхаемому потоку воздуха;создают график, представляющий объем выдоха при выдохе, причем график имеет форму;определяют достоверность измерения объема выдоха при выдохе; иоценивают на основе формы графика характеристики функции легких субъекта.2. Способ по п. 1, в котором этап, на котором оценивают характеристики функции легких субъекта, выполняют в зависимости от определения того, что измерение объема выдоха при выдохе является достаточно достоверным.3. Способ по п. 1, в котором этап, на котором определяют достоверность измерения объема выдоха, основан на форме графика.4. Способ по п. 3, в котором этап, на котором ...

УСТРОЙСТВО И СИСТЕМА ДЛЯ МОНИТОРИНГА ИНФОРМАЦИИ О ПУЛЬСЕ СУБЪЕКТА

СПОСОБ УПРАВЛЕНИЯ СОСТОЯНИЕМ МАССЫ ТЕЛА У ЖИВОТНОГО

... 1. Способ управления состоянием массы у домашнего животного, включающий применение способов определения действительного процентного содержания телесного жира или безжировой массы тела домашнего животного, применение измерений физических данных домашнего животного для использования регрессионного анализа на основе действительного процентного содержания телесного жира или безжировой массы тела, выведение одного или более уравнений на основе регрессионного анализа, прогнозирование процентного содержания телесного жира или безжировой массы тела у домашнего животного и применение прогнозированного процентного содержания телесного жира или безжировой массы тела для предоставления эффективного режима снижения массы для домашнего животного.2. Способ по п.1, в котором способ определения действительного процентного содержания телесного жира или безжировой массы тела домашнего животного представляет собой двухэнергетическую рентгеновскую абсорбциометрию.3. Способ по п.1 или 2, в котором домашним животным ...

СПОСОБ И СИСТЕМА ДЛЯ РЕГИСТРАЦИИ ИНФОРМАЦИИ О ДЫХАНИИ

... 1. Способ регистрации информации о дыхании пользователя, при этом способ содержит этапы, на которых:- выдают пользователю инструкцию выполнять на устройстве движение, отражающее его дыхательную деятельность;- формируют, посредством упомянутого устройства, сигнал, отражающий упомянутое движение;- получают информацию о дыхании пользователя по упомянутому сигналу.2. Способ по п.1, при этом упомянутый способ дополнительно содержит этап выбора части сигнала, имеющей периодическое изменение;при этом упомянутый этап получения заключается в получении информации о дыхании пользователя из упомянутой части сигнала.3. Способ по п.2, в котором период изменения упомянутой части сигнала находится в пределах предварительно заданного диапазона.4. Способ по п.1, при этом упомянутый способ дополнительно содержит этап предоставления пользователю упомянутой полученной информации о дыхании.5. Способ по п.1, при этом упомянутый способ дополнительно содержит этап предоставления пользователю инструкции по дыханию ...

СИСТЕМА И СПОСОБ ОБНАРУЖЕНИЯ ЗНАЧИМЫХ АРИТМИЧЕСКИХ СОБЫТИЙ ПОСРЕДСТВОМ ФОТОПЛЕТИЗМОГРАММЫ(PPG) И АКСЕЛЕРОМЕТРА

УСТРОЙСТВО, СИСТЕМА И СПОСОБ ВЫДЕЛЕНИЯ ФИЗИОЛОГИЧЕСКОЙ ИНФОРМАЦИИ

УСТРОЙСТВО И СПОСОБ ОПРЕДЕЛЕНИЯ СИГНАЛА ОБЪЕМА ДЫХАНИЯ ПО ДАННЫМ ИЗОБРАЖЕНИЯ

УСТРОЙСТВО ДЛЯ ОБНАРУЖЕНИЯ ФИЗИЧЕСКОГО ДВИЖЕНИЯ И СПОСОБ УПРАВЛЕНИЯ УСТРОЙСТВОМ ДЛЯ ОБНАРУЖЕНИЯ ФИЗИЧЕСКОГО ДВИЖЕНИЯ

... 1. Устройство для обнаружения физического движения, которое содержит основной блок, снабженный датчиком ускорения для измерения ускорения упомянутого основного блока и блоком управления, и выполнено с возможностью обнаружения физических движений пользователя, когда упомянутый основной блок установлен на предварительно заданной части пользователя,при этом упомянутый блок управления содержитизмерительный элемент, выполненный с возможностью обнаружения, коснулась ли или нет грунта одна из ног упомянутого пользователя, на основании зарегистрированных значений из упомянутого датчика ускорения,причем в пределах одного цикла передвижения период, в течение которого упомянутый пользователь стоит на первой ноге с момента времени, когда упомянутый измерительный элемент обнаруживает, что упомянутая первая нога коснулась грунта, до момента времени, когда упомянутый измерительный элемент обнаруживает, что вторая нога коснулась грунта, определяется как период первой позиции, ив пределах одного цикла передвижения ...

МУЛЬТИФОКУСНЫЕ СОНИКАЦИИ ДЛЯ ГИПЕРТЕРМИЧЕСКИХ ЛЕЧЕБНЫХ ВОЗДЕЙСТВИЙ С ИСПОЛЬЗОВАНИЕМ УЛЬТРАЗВУКА, СФОКУСИРОВАННОГО ПОД КОНТРОЛЕМ МАГНИТНО-РЕЗОНАНСНОЙ ТОМОГРАФИИ

... 1. Устройство (10) для умеренно гипертермического лечебного воздействия, содержащееустройство (12) визуализации, которое создает изображение (34) для планирования;фазированную решетку ультразвуковых преобразователей (50);матрицу драйверов (52) ультразвуковых преобразователей для индивидуального управления ультразвуковыми преобразователями фазированной решетки, чтобы генерировать мультифокусные соникации в целевой области;один или более процессоров (30, 32, 34), запрограммированных с возможностьюприема целевого температурного профиля на основе изображения для планирования, ивычисления мощности, частоты и относительной фазы для драйверов преобразователей матрицы драйверов ультразвуковых преобразователей, которые могут побуждать фазированную решетку ультразвуковых преобразователей формировать картину мультифокусной соникации, сконфигурированную с возможностью нагревания целевой области с целевым температурным профилем, ивычисления мощностей, частот и относительных фаз для числа фокусов таким ...

System zum patientenspezifischen Modellieren von Blutfluss

System zum Bestimmen von kardiovaskulären Informationen für einen Patienten, wobei das System Folgendes umfasst: wenigstens ein Computersystem, das konfiguriert ist, um: patientenspezifische Daten bezüglich einer Geometrie einer anatomischen Struktur des Patienten zu empfangen, wobei die anatomische Struktur wenigstens einen Abschnitt einer Mehrzahl an Koronararterien, die von einer Aorta ausgehen, beinhaltet; basierend auf den patientenspezifischen Daten ein dreidimensionales Modell zu erzeugen, das einen ersten Abschnitt der anatomischen Struktur repräsentiert, wobei der erste Abschnitt der anatomischen Struktur wenigstens den Abschnitt der Mehrzahl an Koronararterien beinhaltet; wenigstens teilweise basierend auf einer Masse oder einem Volumen des Myokardgewebes ein physikbasiertes Modell bezüglich einer Blutflusseigenschaft im ersten Abschnitt der anatomischen Struktur zu erzeugen; und wenigstens teilweise basierend auf dem dreidimensionalen Modell und dem physikbasierten Modell eine ...

Oszillogrammfilterung von Radial-MRI-Daten

System, welches aufweist: einen Datenempfänger, der ausgebildet ist zum Empfangen von radial geordneten Magnetresonanzrohdaten; einen Sinogrammgenerator, der ausgebildet ist zum Erzeugen eines ersten Sinogramms, welches einen Sichtwinkel als Funktion einer Ausleserichtung für die Magnetresonanzdaten darstellt; einen Prozessor, der ausgebildet ist zum Erzeugen eines Oszillogramms mit einer Winkelfrequenzachse, welches Oszillogramm einer Fourier-Transformation des ersten Sinogramms entspricht; ein Filtermodul, das ausgebildet ist zum selektiven Ausfiltern einer Projektion, die entlang einer ausgewählten Achse des Oszillogramms gebildet ist, wobei die ausgewählte Achse orthogonal zu der Winkelfrequenzachse ist; und ein Ausgangsmodul, das ausgebildet ist zum Bilden eines zweiten Sinogramms entsprechend einer Transformation der gefilterten Projektion.

Verfahren und Vorrichtung zur Messung von Atemweg-Widerstand und Lungennachgiebigkeit

Die Messung des Atemwegswiderstandes und/oder der Lungen-Compliance während der nicht gezwungenen Ausatmung wird unter Verwendung eines anfänglichen Verschlusses der Ausatmung durchgeführt, gefolgt von der Entfernung des Verschlusses oder des Öffnens eines Verschlusses. Das Messgerät kann einen einzigen Sensor verwenden, um sowohl Druck als auch Durchfluss zu messen. Eine Drucküberwachung kann erkennen, dass die Ausatmung nicht zwangsläufig gezwungen ist, einen Fehler zu signalisieren oder eine Druck- und Durchflussmessung aus einer erzwungenen Ausatmungsstudie abzulehnen.

Datenanalysesystem

Temperaturerfassungssystem, umfassend:einen Temperatursensor für den Einsatz in oder am Körper eines weiblichen menschlichen Benutzers zum Erhalten einer Vielzahl von Temperaturmesswerten von dem weiblichen menschlichen Benutzer, wobei der Temperatursensor eine Auflösung von mindestens 0,03 °C, vorzugsweise mindestens 0,01 °C, aufweist;einen Speicher zum Speichern jedes der Vielzahl von Temperaturmesswerten;einen Prozessor zum Digitalisieren jedes der Vielzahl von Temperaturmesswerten;eine Stromversorgung; undeine Kommunikationsschnittstelle zum Kommunizieren der Vielzahl von digitalisierten Temperaturmesswerten an einen zentralen Server, wobei die Kommunikationsschnittstelle eine mit dem Temperatursensor verbundene erste Kommunikationsschnittstelle zum Kommunizieren der Vielzahl von digitalisierten Temperaturmesswerten an eine Zwischenvorrichtung und eine zweite Kommunikationsschnittstelle an der Zwischenvorrichtung zum Kommunizieren der Vielzahl von digitalisierten Temperaturmesswerten ...

Vorrichtung zur Auswertung der Gelbkörperfunktion, System zur Auswertung der Gelbkörperfunktion und Steuerverfahren dafür

Eine Vorrichtung zur Auswertung der Gelbkörperfunktion gemäß der vorliegenden Erfindung umfasst eine Einheit zur Gewinnung der Körpertemperatur (310, 390), welche Basaltemperaturdaten mit Informationen über die Basaltemperaturmesswerte gewinnt, eine Einheit zur Gewinnung eines Menstruationszyklus (310, 390), die Informationen über einen Menstruationsanfangstag und einen Menstruationsendtag, der zu dem Menstruationsanfangstag gehört, gewinnt, eine Auswertungseinheit (310), welche die Gelbkörperfunktion basierend auf Basaltemperaturmesswerten, die, gemessen werden, auswertet, und eine Ausgabeeinheit (310, 390, 340), die ein Ergebnis der Auswertung der Gelbkörperfunktion von der Auswertungseinheit ausgibt.

SYSTEM FÜR DIE UEBERWACHUNG DER GESUNDHEIT, DES WOHLBEFINDENS UND DER KONDITION

Method for monitoring of blood components

Data analysis system and method

Blood monitoring

Analysis of breathing data

Device to determine visuo-spatial ability

The device (10) disclosed herein assists in the diagnosis and classification of neurodegenerative diseases through the assessment of a subject's visuo-spatiai ability, The device (10) has a touch-screen display (11) into which a user can input data utilising a stylus (13) or the like. A position reader is provided, linked to a position data storage means and also a timer to link a time value to said position data, the time value being stored in a time data storage means. Storage means is also provided for preset-value data relating to known data on medical conditions, with the preset-value data having been produced in accordance with an evolutionary algorithm. A comparator compares the user input data with the preset-value data, and the result is output.

Apparatus and method for estimating energy expenditure

An energy expenditure estimating apparatus is disclosed with an accelerometer input configured to receive accelerometer data from an accelerometer and an ECG input configured to receive ECG data from an ECG sensor. A parameter estimation module is configured to calculate an ECG-derived respiration rate and/or other parameters including, heart rate above sleep, frequency-domain heart rate variability, accelerometer activity count, using the ECG and accelerometer data. There is further an energy expenditure estimating apparatus which estimates energy expenditure using the parameters received from the parameter estimation module.

Respiration rate extraction from cardiac signals

Measurement of respiratory function

Method and apparatus for measuring expended energy

Systems, Devices and methods relating to motion data

Electrocardiogra-based blood glucose level monitoring

Method and system for measuring and displaying biosignal data to a wearer of a wearable article

An electronics module receives biosignals, such as ECG, electrocardiogram, signals, from sensors on a wearable article and processes these signals to provide data and information to a user electronic device, such as a mobile phone. The user electronic device and/or electronics module is operable to determine whether the quality of the signal is above or below a predetermined level and to display a real-time biosignal trace on the user electronic device when the quality of the signal is high. The high-quality signal is also stored on user electronic device. When the signal quality is low, the user electronic device displays a composite trace instead of a real-time trace. The composite signal being composed of the stored high-quality trace modified by a current biosignal characteristic (such as current R-R value). The quality of the signal may be determined by an activity level of the user or motion level such as determining whether the wearer of the electronics module is relatively stationary ...

Virtual diagnostic test panel device, system, method and computer readable medium

Virtual diagnostic test panel device, system, method and computer readable medium

Virtual diagnostic test panel device, system, method and computer readable medium

ENVIRONMENT LIGHT DELETION IN A OXIMETER

PROCEDURE AND DEVICE FOR THE EVALUATION AND PROCESSING OF PHOTOPLETHYSMOGRAFI SIGNALS BY WAVE TRANSFORMATION ANALYSIS

SYSTEM FOR THE MONITORING OF THE HEALTH, THE WELL-BEING AND THE CONDITION

ENVIRONMENT LIGHT DELETION IN A OXIMETER

ENVIRONMENT LIGHT DELETION IN A OXIMETER

ENVIRONMENT LIGHT DELETION IN A OXIMETER

ENVIRONMENT LIGHT DELETION IN A OXIMETER

ENVIRONMENT LIGHT DELETION IN A OXIMETER

ENVIRONMENT LIGHT DELETION IN A OXIMETER

ENVIRONMENT LIGHT DELETION IN A OXIMETER

ENVIRONMENT LIGHT DELETION IN A OXIMETER

ENVIRONMENT LIGHT DELETION IN A OXIMETER

ENVIRONMENT LIGHT DELETION IN A OXIMETER

ENVIRONMENT LIGHT DELETION IN A OXIMETER

Biological signal measurement device, biological state inference device, and biological state inference system

Provided are a biological signal measurement device, a biological state inference device, and a biological state inference system using the same, capable of acquiring a variety of biological information and applicable in medical fields or the like. This biological signal measurement device 1 is equipped with three biological signal detection units, including a left upper part biological signal detection unit 11, a right upper part biological signal detection unit 12, and a lower part biological signal detection unit 13. This biological state inference device 1 combines as appropriate each of the time series data obtained from the three biological signal detection units 11 to 13 and uses the same to obtain a precise inference-use processing waveform from which electrical noise has been eliminated. Because the precision of an inference-use processing waveform corresponding to the target biological information, such as breathing and heart sound, increases, the precision of inferring the biological ...

Method and system for measuring in-ear effective sound exposure under an earplug or without an earplug and for determining a wearer induced disturbance

Personalised calibration methods and devices adapted to identify acoustical corrections to be applied for in-ear dosimetry. The acoustical corrections allow to convert a measured acoustic pressure within the ear-canal of a user to an equivalent acoustic pressure at the ear-drum and/or in free-field. The methods and devices also allow to distinguish noises originating from the user from noises of the environment in the ear occluded by an earplug. Such a distinction is done using two microphones to simultaneously measure the acoustic pressure within the ear-canal and outside the ear-canal. The device may be used to determine a cumulative sound pressure level dosage for which a user being exposed to surrounding sounds over a predetermined period of time.

MARKING A COMPUTERIZED MODEL OF A CARDIAC SURFACE

Described embodiments include a system that includes an electrical interface and a processor. The processor is configured 5 to receive, via the electrical interface, an electrocardiographic signal from an electrode within a heart of a subject, to ascertain a location of the electrode in a coordinate system of a computerized model of a surface of the heart, to select portions of the model responsively to the ascertained location, such that 0 the selected portions are interspersed with other, unselected portions of the model, and to display the model such that the selected portions, but not the unselected portions, are marked to indicate a property of the signal. Other embodiments are also described. 0c CC~j ...

Multivariate residual-based health index for human health monitoring

Ambulatory or in-hospital monitoring of patients is provided with early warning and prioritization, enabling proactive intervention and amelioration of both costs and risks of health care. Multivariate physiological parameters are estimated by empirical model to remove normal variation. Residuals are tested using a multivariate probability density function to provide a multivariate health index for prioritizing medical effort.

Diagnostic method for detection of fluid changes

C:\Interwoen\NRPortbl\DCC\DER493206_l.doex- 1/1/2019 A method for monitoring changes in a medium in a patient's head, the method comprising: placing a headset on the patient's head, wherein the headset comprises: a housing; a processor in the housing; a transmitter; and a receiver coupled with the headset such that it is located on approximately an opposite side of the patient's head from the transmitter when the headset is applied to the patient's head; transmitting from the transmitter a first time-varying magnetic field comprising a first plurality of frequencies that are harmonics of a first fundamental frequency; receiving the first time-varying magnetic field with the receiver; determining at least one of a first phase shift or a first magnitude change between the transmitted first magnetic field and the received first magnetic field; transmitting from the transmitter, at a later time, a second time-varying magnetic field comprising a second plurality of frequencies that are harmonics ...

Systems and methods for display device and sensor electronics unit communication

SYSTEMS AND METHODS FOR DISPLAY DEVICE AND SENSOR ELECTRONICS UNIT COMMUNICATION Methods and apparatus are provided for communication among display devices and sensor electronics unit in an analyte monitoring system. The analyte monitoring system may include a sensor that is configured to perform measurements indicative of analyte levels. The sensor may be communicatively coupled to the sensor electronics unit. The sensor electronics unit may be configured to transmit data indicative of analyte levels to the display devices using one or more communication protocols. Furthermore, the sensor electronics unit may be configured to operate in multiple modes, and switch between the modes in response to commands received from the display devices. Related systems, methods, and articles of manufacture are also described.

Methods and systems for improving the reliability of orthogonally redundant sensors

A method of calibrating an orthogonally redundant sensor device for determining the concentration of glucose in a body of a user, said sensor device including at least an electrochemical glucose sensor and an optical glucose sensor, the method comprising: receiving a first signal from the electrochemical glucose sensor; receiving a second signal from the optical glucose sensor; performing a respective integrity check on each of said first and second signals; determining whether the first signal can be calibrated, and whether the second signal can be calibrated, wherein said determination is made based on whether the first signal and the second signal pass or fail their respective integrity checks; if it is determined that the first signal can be calibrated, calibrating said first signal to generate an electrochemical sensor glucose (SG) value; if it is determined that the second signal can be calibrated, calibrating said second signal to generate an optical sensor glucose (SG) value; and ...

Radiofrequency (RF) transmission system to find tissue proximity

A method includes receiving, from a probe that comprises electrodes and is positioned inside a cavity in an organ of a patient, (i) proximity signals indicative of 5 proximity of the electrodes to a wall of the cavity, and (ii) position signals indicative of positions of the electrodes within the cavity. Based on the proximity signals and the position signals, at least a portion of a volume of the cavity is represented by a sphere model 10 including multiple spheres. An estimated contour of the wall of the cavity is calculated based on the sphere-model. The estimated contour of the wall is presented to a user. Nt 04 CY) Co Q) CY) Q) LO LO 0) LO CV) CY) CY) (N ...

Method for data reduction and calibration of an OCT-based blood glucose monitor

Methods and Devices for the Detection of Hypopnea

System and method for reconstructing cardiac activation information

An example system and method of reconstructing cardiac activation information are disclosed. A first cardiac signal and a second cardiac signal are processed via a computing device to determine whether there is a point of change in a derivative of the first cardiac signal with respect to a derivative of the second cardiac signal above a threshold. An activation onset time is assigned in the first cardiac signal at the point of change to define cardiac activation indicating a beat in the first cardiac signal if it is determined that the point of change is above the threshold.

Monitoring system

NMR systems for in vivo detection of analytes

Cardiovascular analyzer

The present invention relates to a cardiovascular diagnostic system which enables early detection of cardiovascular diseases and defines their causes. Unlike known electrocardiographs, the cardiovascular diagnosis system can further measure elastic coefficient of blood vessels (the degree of arteriosclerosis), blood vessel compliance, blood flow, and blood flow resistance and velocity in blood vessel branches of the right and left coronary arteries. The elastic coefficient shows organic changes to blood vessels. The compliance shows organic and functional changes of blood vessels simultaneously. The blood flow shows blood flow resistance.

PROCEDURE FOR DERIVING RELIABLE INFORMATION ON RESPIRATORY ACTIVITY FROM HEART PERIOD MEASUREMENT

Heart rate path optimizer

A device for determining a heart rate of a user has a PPG sensor and an accelerometer to compensate for acceleration artifacts within the PPG signal. The device transforms time domain PPG and accelerometer signals into the frequency domain using a Fourier transformation and utilizes the Fourier coefficient magnitudes as indicative of the probability of candidate heart rate values. Candidate heart rate values are determined at sampling times over a time interval and a most probable heart rate path during the time interval is determined using a reward/penalty algorithm.

System, apparatus and method for measurement of muscle stiffness

A system, an apparatus, and a method for measuring muscle stiffness in a predetermined joint of an individual are provided. The system and apparatus comprises a measuring unit and a processing unit. The measuring unit is configured to be applied to a body segment of the predetermined joint. The processing unit is configured to: receive a plurality of data sets from the at least one measurement device, analyze the plurality of data sets for one or more indications of an elicited stretch reflex, and calculate a muscle stiffness score. The muscle stiffness score is based on at least a difference between a first stiffness and a second stiffness. The first stiffness is determined from the first subset, and the second stiffness is determined from the second subset.

Method and system for non-invasively monitoring biological or biochemical parameters of individual

A system and method are presented for use in monitoring one or more conditions of a subject's body. The system comprises a control unit which comprises an input port for receiving image data and data indicative of at least one external stimulation (external field) applied to a portion of the subject's body during collection of the image data therefrom, a memory utility, and a processor utility. The image data is indicative of a sequence of speckle patterns generated by the portion of the subject's body according to a certain sampling time pattern. The processor utility is configured and operable for carrying out the following: processing the image data utilizing the data indicative of the applied external field(s), said processing comprising determining a spatial correlation function between successive speckle patterns in the sequence, and determining a time varying spatial correlation function in the form of a time-varying function of at least one feature of the correlation function indicative ...

Method and system for noise cleaning of photoplethysmogram signals

METHOD AND SYSTEM FOR NOISE CLEANING OF PHOTOPLETHYSMOGRAM A method and system is provided for noise cleaning of photoplethysmogram signals. The method and system is disclosed for noise cleaning of photoplethysmogram signals for estimating blood pressure of a user; wherein photoplethysmogram signals are extracting from the user; the extracted photoplethysmogram signals are up sampled; the up sampled photoplethysmogram signals are filtered; uneven baseline drift of each cycle is removed from the up sampled and filtered photoplethysmogram signals; outlier cycles of the photoplethysmogram signals are removed and remaining cycles of the photoplethysmogram signals are modeled; and time domain features are extracted from originally extracted and modeled photoplethysmogram signals for estimating blood pressure of the user. [To be published with Figure 2] An up sampling module (206) An image capturing device (202) A filtering module (208) A baseline drift removal module (210) A mobile communication ...

Exercise system and method

We here describe an exercise system and control method thereof to obtain exercise protocols relating to the individual user's optimal exercise intensity. The system and method comprise the monitoring of the transition between the aerobic and anaerobic training zones and an estimate of the maximal lactate steady state, which is an important physiological indicator of the user's cardio respiratory fitness. Together with individual models of how the user's heart rate responds to exercise intensity, it is possible to predict the needed exercise intensity that should be performed to obtain the wanted exercise goal. The analysis can (preferably) be performed in real-time during exercise.

Diagnostic system for detection of fluid changes

A diagnostic system for monitoring changes in a medium is disclosed. The system includes a transmitter configured to generate and transmit a time-varying magnetic field into a medium responsive to a first signal. The system also includes a receiver positioned on an opposite side of the medium from the transmitter and configured to generate a second signal responsive to a received magnetic field at the receiver. The system also includes a processing unit configured to determine a phase shift between the transmitted magnetic field and the received magnetic field for a plurality of frequencies of the transmitted time-varying magnetic field.

Method of managing a weight condition in an animal

A methodology of managing a weight condition of a companion animal by determining body fat composition of the companion animal and an appropriate weight loss regimen based on the body fat percentage is provided. More specifically, described herein is a clinically useful tool and methodology to apply to overweight and obese animals for use in managing a weight condition of the overweight or obese animal by determining the body fat percentage of the animal and providing a weight loss regimen.

Method and system for modeling blood flow with boundary conditions for optimized diagnostic performance

Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

Methods and systems for improving the reliability of orthogonally redundant glucose sensors

Methods and systems for sensor calibration and sensor glucose (SG) fusion are used advantageously to improve the accuracy and reliability of orthogonally redundant glucose sensor devices, which may include optical and electrochemical glucose sensors. Calibration for both sensors may be achieved via fixed-offset and/or dynamic regression methodologies, depending, e.g., on sensor stability and Isig-Ratio pair correlation. For SG fusion, respective integrity checks may be performed for SG values from the optical and electrochemical sensors, and the SG values calibrated if the integrity checks are passed. Integrity checks may include checking for sensitivity loss, noise, and drift. If the integrity checks are failed, in-line sensor mapping between the electrochemical and optical sensors may be performed prior to calibration. The electrochemical and optical SG values may be weighted (as a function of the respective sensor's overall reliability index (RI)) and the weighted SGs combined to obtain ...

Method and system for patient-specific modeling of blood flow

C:\Users\kll\AppData\Local\Temp12713 IDAOBAFC.DOCX-22 12/2015 Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

Tissue-Integrating Sensors

TISSUE-INTEGRATING SENSORS Tissue-integrating biosensors, systems comprising these sensors and methods of using these sensors and systems for the detection of one or more analytes are provided.

METHOD AND SYSTEM FOR DETERMINING POSTURAL BALANCE OF A PERSON

A method and system for determining postural balance of the person is provided. The disclosure provides a single limb stance body balance analysis system which will aid medical practitioners to analyze crucial factor for fall risk minimization, injury prevention, fitness and rehabilitation. Skeleton data was captured using Kinect. Two parameters vibration-jitter and force per unit mass (FPUM) are derived for each body part to assess postural stability during SLS. Further, the vibration and force imposed on each joint a first balance score was quantified. A first balance score and a second balance are also calculated by combining vibration index and SLS duration to indicate the postural balance of the person. The vibration index is computed from the vibration profile associated different body segments. [Abstract to be published with Fig. 1] E& z *z 0 0 ...

Tissue-Integrating Sensors

Tissue-integrating biosensors, systems comprising these sensors and methods of using these sensors and systems for the detection of one or more analytes are provided.

Method and system for patient-specific modeling of blood flow

Abstract A system for determining cardiovascular information for a patient, the system comprising: at least one computer system configured to: receive patient specific data regarding a geometry of an anatomical structure of the patient; create a three-dimensional model representing at least a portion of the anatomical structure of the patient based on the patient-specific data, the three-dimensional model representing at least one fluid flow inlet and at least one fluid flow outlet; create at least one boundary condition model representing fluid flow through at least one of the at least one inlet or the at least one outlet, based at least in part on modeling a condition of hyperemia; and determine first information regarding a blood flow characteristic within the anatomical structure of the patient based on the three dimensional model and the at least one boundary condition model. cCD Co co VC C C) C) f I co C, Loij 0~ u~ EtIt C3oI ...

Analyte monitoring device and methods of use

MULTIVARIATE RESIDUAL-BASED HEALTH INDEX FOR HUMAN HEALTH MONITORING

Ambulatory or in-hospital monitoring of patients is provided with early warning and prioritization, enabling proactive intervention and amelioration of both costs and risks of health care. Multivariate physiological parameters are estimated by empirical model to remove normal variation. Residuals are tested using a multivariate probability density function to provide a multivariate health index for prioritizing medical effort.

SYSTEM FOR NON-INVASIVE EXAMINATION OF BLOOD ENVIRONMENT PARAMETERS

A system for non-invasive examination of a user's blood environment parameters that includes having at least four user-input sensors (1, 2, 3, 4) operably configured to measure a partial pressure of O2 and CO2 in a user's blood, a temperature of the user, and a hemoglobin content in the user's blood, an external electronic display unit (11), and a computing unit (9) with a communication interface (12) and communicatively coupled to the external electronic display unit (11) and the least four user-input sensors (1, 2, 3, 4), the computing unit (9) operably configured to cause a user's blood environment parameters to display on the external electronic display unit (11) through use of a mathematical software application resident thereon and employing a model of the user's internal environment based on a mathematical expression of an equation for hemoglobin buffer and utilizing the data from the user-input sensors.

SYSTEM FOR MONITORING HEALTH, WELLNESS AND FITNESS

A detecting, monitoring and reporting system includes a sensor device which generates data indicative of at least one activity, GSR and heat flow of an individual and data derived therefrom when placed in proximity with the body. A remote central monitoring unit generates analytical status data from this data and analytical status data that has previously been generated. A data storage device stores the data received and generated by the central monitoring unit. The system includes means for establishing electronic communication between the sensor device and the central monitoring unit, and means for transmitting the data to a recipient. The sensor device may also generate data indicative of contextual parameters of the individual, which may then be used when generating the analytical status data. The system may be used for monitoring and providing feedback relating to the degree to which an individual has followed a suggested routine.

A SYSTEM AND A METHOD FOR RESPIRATORY MONITORING OF A SUBJECT

A system (100) for respiratory monitoring of a subject (100) comprises: a bioimpedance measurement sensor (110), which is configured for arrangement in relation to the subject for acquiring a bioimpedance signal; a processing unit (120), which is configured to receive the acquired bioimpedance signal and receive a reference signal, the reference signal representing a respiratory effort of the subject or a respiratory airflow at a time of bioimpedance signal acquirement, the processing unit being further configured to divide the bioimpedance signal into an effort component representing a respiratory effort of the subject and a flow component representing a respiratory airflow of the subject based on the received bioimpedance signal and the received reference signal.

PHYSIO-SENSORY TRANSDUCTION METHOD AND DEVICE

L'invention propose un procédé et un dispositif permettant de transcrire un signal physiologique, typiquement représentatif d'une activité cérébrale, sous la forme de signaux sensoriels perceptibles par un utilisateur humain, typiquement des signaux acoustiques. Pour ce faire, un signal physiologique est acquis (E1) puis analysé de manière à y détecter (E20) des motifs qui sont ensuite paramétrés (E30) dans le domaine temporel. Un ou plusieurs paramètres de ces motifs sont utilisés pour déterminer un ou plusieurs paramètres des signaux sensoriels générés (E40) et/ou pour déterminer un ou plusieurs paramètres d'enveloppes temporelles utilisées pour moduler les signaux sensoriels. Application en particulier à la transduction neuro-acoustique.

DIAGNOSTIC SYSTEM FOR DETECTION OF FLUID CHANGES

SYSTEM AND METHOD FOR MONITORING AND DETERMINING PATIENT PARAMETERS FROM SENSED VENOUS WAVEFORM

Devices, systems, and methods for monitoring patient hemodynamic status, systemic vascular resistance, reversal of cardiac and respiratory rates, and patient respiratory volume or effort are disclosed. A peripheral venous pressure is measured and used to detect levels, changes, or problems relating to patient blood volume. The peripheral venous pressure measurement is transformed from the time domain to the frequency domain for analysis. A heart rate frequency is identified, and harmonics of the heart rate frequency are detected and evaluated to determine, among other things, hypovolemia or hypervolemia, systemic vascular resistance, and cardiac and respiratory rates, and patient respiratory volume or effort.

SYSTEMS AND METHODS FOR DISPLAY DEVICE AND SENSOR ELECTRONICS UNIT COMMUNICATION

Methods and apparatus are provided for communication among display devices and sensor electronics unit in an analyte monitoring system. The analyte monitoring system may include a sensor that is configured to perform measurements indicative of analyte levels. The sensor may be communicatively coupled to the sensor electronics unit. The sensor electronics unit may be configured to transmit data indicative of analyte levels to the display devices using one or more communication protocols. Furthermore, the sensor electronics unit may be configured to operate in multiple modes, and switch between the modes in response to commands received from the display devices. Related systems, methods, and articles of manufacture are also described.

METHODS, SYSTEMS, AND DEVICES FOR SENSOR FUSION

A single, optimal, fused sensor glucose value may be calculated based on respective sensor glucose values of a plurality of redundant working electrodes (WEs) of a glucose sensor. Respective electrochemical impedance spectroscopy (EIS) procedures may be performed for each of the WEs to obtain values of membrane resistance (Rmem) for each WE. A noise value and a calibration factor (CF) value may be calculated for each WE, and respective fusion weights may be calculated for Rmem, noise, and CF for each WE. An overall fusion weight may then be calculated based on the WE' s Rmem fusion weight, noise fusion weight, and CF fusion weight, such that a single, optimal, fused sensor glucose value may be calculated based on the respective overall fusion weight and sensor glucose value of each of the plurality of redundant working electrodes.

Devices and methods for respiratory variation monitoring by measurement of respiratory volumes, motion and variability

This invention is directed to devices and methods for assessing a patient. The devices have at least one impedance measuring element functionally connected to a programmable element, programmed to analyze an impedance measurement, and to provide an assessment of at least one respiratory parameter of the patient. Preferably the device includes electronics which aid in calibration, signal acquisition, conditioning, and filtering.

Method and System For Patient-Specific Modeling of Blood Flow

Embodiments include a system for planning treatment for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of an anatomical structure of the patient, create a three-dimensional model representing at least a portion of the anatomical structure of the patient based on the patient-specific data, and determine a first fractional flow reserve within the anatomical structure of the patient based on the three-dimensional model and information regarding a physiological condition of the patient. The at least one computer system may be further configured to receive input from a user regarding a plan of treatment, modify the physiological condition of the patient based on the received input, and determine a second fractional flow reserve within the anatomical structure of the patient based on the modified physiological condition of the patient.

Device, system and method for monitoring and communicating biometric data of a diver

A system and method for monitoring biometric data of a diver and signaling those data from a first communication device to other communication devices, e.g., those of other divers, on a ship or buoy. A signal generated from a device of the diver can generate a diver identifier, an indication of a stress state of the diver and the diver's location.

Blood Flow Monitoring

The present invention relates to a method of utilizing photoplethysmography obtained from a central site and a non-central site to detect a low blood flow or low blood volume condition. Also disclosed are apparatuses and systems designed to acquire and process physiological information based on photoplethysmograpy signal information from dual sites.

Devices for diagnosing sleep apnea or other conditions and related systems and methods

A system includes a sensor device having a body configured to be inserted into an airway of a patient and one or more sensors mounted in or on the body. The one or more sensors are configured to collect sensor data associated with the airway of the patient. The system also includes a signal analyzer configured to analyze the sensor data. The one or more sensors could include one or more microphones. The signal analyzer could identify volume and/or pitch characteristics of the sensor data, perform pattern recognition to identify one or more patterns using the volume and/or pitch characteristics, and use the one or more patterns to identify a type, a location, and/or a degree of airway obstruction. This could be done, for instance, to determine if the patient suffers from obstructive sleep apnea or other condition that affects his or her airway.

Patient monitoring system

A patient support apparatus includes a monitoring system having a first detector and a controller. The first detector detects electromagnetic radiation from a first field of view of the first detector and providing a signal indicative of characteristics of the electromagnetic radiation. The controller includes a processor coupled to the first detector and a memory device including instructions that, when executed by the processor, cause the processor to processes the signal from the first detector, translate the signal into an array of data, and evaluate the data in the array to determine characteristics of a patient positioned in the first field of view.

Classification of impacts from sensor data

Systems and methods are provided for classifying an impact to a head of a human being as one of a plurality of event classes. A sensor interface is configured to determine an acceleration at a location of interest on the human being from provided sensor data in response to the impact. A feature calculation component is configured to calculate a plurality of impact parameters from the determined acceleration at the location of interest. A pattern recognition classifier is configured to associate the impact with an associated event class of at least three associated event classes according to the calculated plurality of impact parameters. A post-processing component is configured to communicate the associated event class an observer via an associated output device.

System for continuous measuring, recording and monitoring of the splanchnic tissue perfusion and the pulmonary physiological dead space, and use thereof

The present invention relates to a new system for measuring, recording and monitoring the splanchnic tissue perfusion and the pulmonary physiological dead space in an automated way, both continuously and intermittently, and in real time, which is easy to manage and generates information easy to interpret. Said system comprises at least four measuring devices of medical parameters, connected to a device receiving, converting, storing, integrating, processing, and allowing the management and display of the data recorded in the measurements and the parameters estimated by the same. For this purpose, said device comprises a specific computer program of estimation of parameters related to the measurement of the splanchnic tissue perfusion and the pulmonary physiological dead space, from the data derived from the measuring devices. Likewise, the present invention is related to the use of a device for measuring, recording and monitoring of the splanchnic tissue perfusion and the pulmonary physiological dead space.

System and method for reconstructing cardiac activation information

An example system and method of reconstructing biological activation information are disclosed. A first biological signal and a second biological signal associated with an organ are processed via a computing device to determine whether there is a point of change in a derivative of the first biological signal with respect to a derivative of the second biological signal above a threshold. An activation onset time is assigned in the first biological signal at the point of change to define biological activation associated with the organ in the first cardiac signal if it is determined that the point of change is above the threshold.

Vessel pulse wave measurement system conducting vessel pulse wave measurement by obtaining pulsation waveform of blood vessel

A vessel pulse wave measurement system performs vessel pulse wave measurement using an optical probe circuit provided with an optical probe including a light emitting element and a light receiving element, a drive circuit, and a detection circuit. A measurement device directly and synchronously feeds back an electrical signal from the optical probe to the drive circuit as a drive signal to generate a self-oscillation signal from the detection circuit, and measures the self-oscillation signal as a vessel pulse wave signal. A controller controls an operating point of at least one of the detection circuit and the drive circuit such that the self-oscillation signal substantially reaches a maximum level thereof.

System and method for measuring mid-arm circumference of a child to determine equipment and medication for pediatric resuscitation

Embodiments of the present invention are directed to a measuring tape for determining equipment sizes and medication dosages to use during the resuscitation of a pediatric patient. In one embodiment, the measuring tape may have a plurality of regions having different colors and/or patterns that identify weight zones that correlate with information and equipment required for resuscitating the pediatric patient. The measuring tape may be wrapped around the arm of the pediatric patient to determine the mid-arm circumference. Once wrapped around the arm, the color and/or pattern in alignment with an opening of the measuring tape may be used to identify a weight zone for the patient which provides the proper equipment size and medication dosages to be used for resuscitating the pediatric patient.

Method of analyzing and processing signals

A physiological measurement system is disclosed which can take a pulse oximetry signal such as a photoplethysmogram from a patient and then analyse the signal to measure physiological parameters including respiration, pulse, oxygen saturation and movement. The system comprises a pulse oximeter which includes a light emitting device and a photodetector attachable to a subject to obtain a pulse oximetry signal; analogue to digital converter means arranged to convert said pulse oximetry signal into a digital pulse oximetry signal; signal processing means suitable to receive said digital pulse oximetry signal and arranged to decompose that signal by wavelet transform means; feature extraction means arranged to derive physiological information from the decomposed signal; an analyser component arranged to collect information from the feature extraction means; and data output means arranged in communication with the analyser component.

Method of analyzing and processing signals

A physiological measurement system is disclosed which can take a pulse oximetry signal such as a photoplethysmogram from a patient and then analyse the signal to measure physiological parameters including respiration, pulse, oxygen saturation and movement. The system comprises a pulse oximeter which includes a light emitting device and a photodetector attachable to a subject to obtain a pulse oximetry signal; analogue to digital converter means arranged to convert said pulse oximetry signal into a digital pulse oximetry signal; signal processing means suitable to receive said digital pulse oximetry signal and arranged to decompose that signal by wavelet transform means; feature extraction means arranged to derive physiological information from the decomposed signal; an analyser component arranged to collect information from the feature extraction means; and data output means arranged in communication with the analyser component.

Method of analyzing and processing signals

A physiological measurement system is disclosed which can take a pulse oximetry signal such as a photoplethysmogram from a patient and then analyse the signal to measure physiological parameters including respiration, pulse, oxygen saturation and movement. The system comprises a pulse oximeter which includes a light emitting device and a photodetector attachable to a subject to obtain a pulse oximetry signal; analogue to digital converter means arranged to convert said pulse oximetry signal into a digital pulse oximetry signal; signal processing means suitable to receive said digital pulse oximetry signal and arranged to decompose that signal by wavelet transform means; feature extraction means arranged to derive physiological information from the decomposed signal; an analyser component arranged to collect information from the feature extraction means; and data output means arranged in communication with the analyser component.

Method and system for patient-specific modeling of blood flow

Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

Method and system for patient-specific modeling of blood flow

Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

Portable monitoring devices and methods of operating same

The present inventions, in one aspect, are directed to a portable activity monitoring device to calculate a number of stairs or flights of stairs traversed by a user, the monitoring device comprising (i) a housing having a physical size and shape that is adapted to couple to the body of the user, (ii) an altitude sensor, disposed in the housing, to detect a change in altitude of the user and, in response thereto, to generate data which is representative of the change in altitude of the user, and (iii) processing circuitry, disposed in the housing and coupled to the motion sensor and the altitude sensor, to calculate a number of stairs or flights of stairs traversed by the user using the data which is representative of a change in altitude of the user.

System for use in administering inhaled nitric oxide gas

Disclosed are systems for use in administering inhaled nitric oxide gas as a therapeutic treatment, where the systems reduce the risk of inducing an increase in pulmonary capillary wedge pressure leading to pulmonary edema in neonatal patients who have hypoxic respiratory failure and are candidates for inhaled nitric oxide treatment, the system comprising a source of pharmaceutically acceptable nitric oxide gas for inhalation, a delivery device suitable for delivering nitric oxide gas from the source to a term or near-term neonate patient, and instructions for use in operating the system.

PERFUSION INDEX SMOOTHER

An embodiment of the present disclosure seeks to smooth a perfusion index measurement through use of a baseline perfusion index measurement and/or through the use of multiple PI calculations. The combination of the baseline perfusion index measurement reduces an error between a calculated measurement of PI and actual conditions. 1. A method of determining an indication of perfusion index in a patient monitor , the method comprising:receiving pleth data;calculating at least two indications of perfusion index using at least two different calculation techniques; anddetermining a final indication of perfusion index based on the at least two indications of perfusion index.2. The method of claim 1 , wherein the final indication of perfusion index is determined by selecting the lowest indication of perfusion index.3. The method of claim 1 , wherein the final indication of perfusion index is determined by statistical analysis.4. The method of claim 1 , wherein the final indication of perfusion index is determined by averaging the at least two indications of perfusion index.5. A method of determining an indication of perfusion index claim 1 , the method comprising:receiving pleth data; anddetermining an indication of perfusion index by utilizing at least one of a first calculation technique and a second calculation technique to determine a resulting indication of perfusion index.6. The method of claim 5 , wherein determining the indication of perfusion index comprises utilizing the calculation technique that will result in the lowest perfusion index value.7. An oximeter comprising:an input capable of receiving intensity signal data responsive to intensity signals acquired from a detector capable of detecting light attenuated by body tissue,a first calculation calculator configured to calculate a first indication of perfusion index using a first calculation technique;a second calculator configured to calculate a second indication of perfusion index using a second calculation ...

Systems and methods for determining respiration information from a photoplethysmograph

A signal representing physiological information may include information related to respiration. A patient monitoring system may generate a plurality of autocorrelation sequences from the signal and combine the autocorrelation sequences to generate a combined autocorrelation sequence. The combined autocorrelation sequence may be analyzed to identify one or more peaks that may correspond to respiration information. Respiration information such as respiration rate may be determined based on the one or more peaks.

Standardized measurement of physiological pressures using an air-charged catheter apparatus

Systems and methods are provided for providing a standardized pressure value representing a transient pressure event within a region of interest within a living body. An air-charged catheter is configured to record pressure data representing the region of interest. A measurement assembly includes a parameter calculation component configured to calculate at least a peak pressure representing the transient pressure event and a time to peak pressure, representing the time necessary to reach the peak pressure, from the recorded pressure data. A standardization component is configured to calculate the standardized pressure value as a function of the peak pressure and the time to peak pressure. A user interface is configured to display at least the standardized pressure value at an associated display.

Haemodynamic monitoring device

A relation is formed between an n-tuple having n components and formed at a first point in time and at least one other n-tuple having n components formed at at least one corresponding later point in time, wherein n is a natural number equal to or greater than 1, and the components comprise at least one derived parameter and/or one read-in data value. If this relationship satisfies a predetermined calibration criterion, a calibration signal is triggered and is displayed, and/or automatically triggers a recalibration of the haemodynamic monitoring device. For example, the pulse contour cardiac output PCCO is derived from the arterial pressure curve as the constituent component of a 1-tuple. As long as this differs from the reference cardiac output CO Ref by less than a predefined threshold value, for example 101 or 15% of the reference cardiac output, parameter determination continues without initiating a new calibration. On the other hand, if the deviation exceeds PCCO-CO ref I, the calibration signal is triggered.

METHOD OF OSCILLOGRAM FILTERING FOR RADIAL MRI DATA

A system includes a data receiver, a sinogram generator, a processor, a filter module, and an output module. The data receiver is configured to receive radial ordered magnetic resonance data. The sinogram generator is configured to generate a first sinogram corresponding to a view angle as a function of a readout direction for the magnetic resonance data. The processor is configured to generate an oscillogram having an angular frequency axis. The oscillogram corresponds to a Fourier transform of the first sinogram. The filter module is configured to selectively filter a peak in a projection formed along a selected axis of the oscillogram, the peak being related to an interference signal such as an RF interference. The selected axis is orthogonal to the angular frequency axis. The output module is configured to form a second sinogram corresponding to a transform of the filtered projection 2. The system of wherein the data receiver is configured to receive spherical ordered data.3. The system of wherein the data receiver is configured to receive at least one of 2D data or 3D data.4. The system of wherein the processor is configured to implement at least one of a Fourier transform or an inverse Fourier transform.5. The system of wherein the processor is configured to implement a Fourier transform along the view angle and along the readout direction.6. The system of wherein the filter module is configured to form the projection using a magnitude component of the oscillogram.7. The system of wherein the filter module is configured to form a 1D projection in a direction aligned with a fast axis of the oscillogram.8. The system of wherein the filter module is configured to implement at least one of a notch filter and a mask filter.9. The system of wherein the filter module is configured to implement a median filter.10. The system of wherein the filter module includes a peak detector.11. The system of wherein the output module is configured to generate an image using the ...

BODY FAT MEASUREMENT DEVICE

A body fat measurement device includes: a measurement unit for measuring a shape of a measurement subject's trunk area; a breathing estimation unit that detects a change over time in the measured trunk area shape and estimates the measurement subject's breathing based on the detected change; a breathing state determination unit that determines whether or not the estimated breathing of the measurement subject is in a state suited to measurement; a state output unit that outputs the estimated breathing state to the exterior in association with a result of the determination; and a fat mass calculation unit that calculates a trunk area fat mass using the body impedance measured by a body impedance measurement unit and a trunk area size based on the trunk area shape measured by the measurement unit. 1. A body fat measurement device comprising:multiple electrodes for making contact with the surface of a measurement subject's body at the measurement subject's trunk area;an impedance measurement means that measures a body impedance of the measurement subject using the multiple electrodes;a measurement means for measuring a shape of the measurement subject's trunk area;an estimation means that detects a change over time in the trunk area shape measured by the measurement means and estimates the measurement subject's breathing based on the detected change;a determination means that determines whether or not the measurement subject's breathing estimated by the estimation means is in a state suited to measurement;a fat mass calculation means that calculates a trunk area fat mass using the body impedance measured by the impedance measurement means and a trunk area size based on the trunk area shape measured by the measurement means; anda control means that controls the impedance measurement means and the fat mass calculation means,wherein the state suited to measurement indicates a stopped state in which the measurement subject has stopped breathing after exhaling;the ...

PHYSIOLOGICAL ACOUSTIC MONITORING SYSTEM

A physiological acoustic monitoring system receives physiological data from an acoustic sensor, down-samples the data to generate raw audio of breathing sounds and compresses the raw audio. The acoustic monitoring system has an acoustic sensor signal responsive to tracheal sounds in a person. An A/D converter is responsive to the sensor signal so as to generate breathing sound data. A decimation filter and mixer down-samples the breathing sound data to raw audio data. A coder/compressor generates compressed audio data from the raw audio data. A decoder/decompressor decodes and decompresses the compressed audio data into decompressed audio data. The decompressed audio data is utilized to generate respiration-related parameters in real-time. The compressed audio data is stored and retrieved so as to generate respiration-related parameters in non-real-time. The real-time and non-real-time parameters are compared to verify matching results across multiple monitors. 1. An acoustic monitoring system inputs an acoustic sensor signal responsive to tracheal sounds of a person and generates breath tags and a respiration rate , the breath tags representing the acoustic envelope of the tracheal sounds and the respiration rate representing the inverse period of the acoustic envelope , the breath tags and respiration rate having a sufficiently low bandwidth to share a data channel with other physiological parameters , the acoustic monitor comprising:an acoustic sensor input;an A/D converter that digitizes the sensor input and outputs a digitized sensor signal;a decimation filter and mixer that reduces the data rate of the digitized sensor signal and outputs a digitized raw audio; andan acoustic parameter processor that generates a respiration rate and breath tags in response to the digitized raw audio.2. The acoustic monitoring system according to further comprising a coder/compressor that compresses the digitized raw audio to generate compressed audio data claim 1 , the ...

MONITORING SYSTEM FOR CARDIAC SURGICAL OPERATIONS WITH CARDIOPULMONARY BYPASS

A monitoring system for cardiac operations with cardiopulmonary bypass comprising: a processor operatively connected to a heart-lung machine; a pump flow detecting device connected to a pump of the heart-lung machine to continuously measure the pump flow value and send it to the processor; a hematocrit reading device inserted inside the arterial or venous line of the heart-lung machine to continuously measure the blood hematocrit value and to send it to the processor; a data input device to allow the operator to manually input data regarding the arterial oxygen saturation and the arterial oxygen tension; computing means integrated in the processor to compute the oxygen delivery value on the basis of the measured pump flow, the measured hematocrit value, the preset value of arterial oxygen saturation, and the preset value of arterial oxygen tension; and a display connected to the processor to display in real-time the computed oxygen delivery value. 1. A method of monitoring a patient's parameters during a cardiac operation with cardiopulmonary bypass and a heart-lung machine , the method comprising:detecting a pump flow (Qp) value from a pump of the heart-lung machine;detecting a hematocrit (HCT) value from the arterial or venous line of the heart-lung machine;obtaining an arterial oxygen saturation (Sat(a)) value derived from an arterial blood of the patient;obtaining an arterial oxygen tension (PaO2) value derived from the arterial blood of the patient;calculating an oxygen delivery (DO2) value;calculating a carbon dioxide production (VCO2) value; anddisplaying a comparison of the DO2 value and the VCO2 value.2. The method of claim 1 , further comprising calculating a hemoglobin (Hb) value from the HCT value.3. The method of claim 2 , further comprising calculating an arterial oxygen content (CaO2) value from the Hb value claim 2 , the Sat(a) value and the PaO2 value.4. The method of claim 2 , further comprising calculating the DO2 value from the pump flow rate Qp ...

Apparatus and method for improving training threshold

The present invention generally relates to a non-invasive biosensor device configured to measure physiological parameters of a subject. In one aspect, a method of determining a training threshold of a subject is provided. The method includes the step of detecting an oxygenation parameter of a tissue of the subject using Near InfraRed Spectroscopy (NIRS). The method further includes the step of processing the oxygenation parameter. Additionally, the method includes the step of determining the training threshold of the subject using the result of the processing. In another aspect, a biosensor device for determining a lactate threshold of a subject during exercise is provided. In a further aspect, a biosensor device for measuring parameters of a subject during exercise is provided.

METHOD TO DETERMINE SODIUM VALUES DESCRIBING THE CONTENT OF 23NA+, AND LOCAL COIL FOR USE IN SUCH A METHOD

In a method to determine at least one sodium value describing the 23Na+ content in at least one region of interest in a target region in the body of a patient, at least one sodium image data set of the target region is acquired with a magnetic resonance imaging device using sodium-23 imaging, the sodium image data set including image data dependent on the occurrence of sodium. The at least one region of interest is defined for which the sodium value is to be determined in the sodium image data set. The sodium value is determined by comparison of the image data in the region of interest with reference image data of at least one subject with a defined 23Na+ content, the reference image data having been acquired with the same sequence. A local coil can be used to implement the method that has a phantom integrated therein that allows the sodium image data set and the reference image data to be acquired together. 1. A method to determine at least one sodium value describing 23N+ content in at least one region of interest in a target region in the body of a patient , comprising:operating a magnetic resonance data acquisition unit with a sequence configured for sodium-23 imaging sequence to acquire at least one sodium image data set of a target region of the body of a patient in the magnetic resonance data acquisition unit, said at least one sodium image data set comprising image data dependent on a presence of sodium in said target region;in a computerized processor, defining at least one region of interest for which a sodium value is to be determined in said sodium image data set; andproviding said processor with reference image data also acquired using said sequence configured for sodium-23 imaging sequence and, in said processor, determining said sodium value by comparing image data in said at least one sodium image data set, that represent a region of interest within said target region, with said reference image data.2. A method as claimed in comprising generating ...

METHOD AND SYSTEM FOR ANALYZING A PATIENT'S RESPIRATORY ACTIVITY AND CORRESPONDING USES

This method for analyzing the respiratory activity of a patient comprises the steps () for acquiring at least one respiratory activity signal comprising at least one elementary signal corresponding to a respiratory cycle, the general form of which may be expressed by x(t)=x+xcos (Φ(t)), wherein Φ(t) is the phase of said elementary signal, and for analyzing () said respiratory activity signal. This analysis () comprising steps () for extracting, from said respiratory activity signal, said elementary signal, for determining () an expression of a phase equation 11. A respiratory assistance device comprising a system for analyzing respiratory activity according to .12. A respiratory monitoring device comprising a system for analyzing respiratory activity according to . The present invention relates to a method and a system for analyzing the respiratory activity of a patient, the method comprising the steps for acquiring at least one respiratory activity signal comprising at least one elementary signal corresponding to a respiratory cycle, the general form of which may be expressed by x(t)=x+xcos (Φ(t)), wherein Φ(t) is the phase of said elementary signal, and for analyzing said respiratory activity signal.It also relates to the applications of the latter to the control of a respiratory assistance device and a respiratory monitoring device.It applies in particular to the detection of respiratory disorders or to the control of artificial ventilation devices.A respiratory activity signal is a signal measuring the variation of a quantity related to the respiratory activity of the patient, such as the air flow rate and pressure or the oxygen and carbon dioxide concentration at the entry of his/her respiratory tracts or the oxygen concentration in the blood. These quantities may be measured with non-invasive measuring apparatuses, for example a flow rate or pressure sensor integrated to a mask placed in front of the mouth of the patient or an oxymeter, or with internal ...

METHOD AND APPARATUS FOR DETERMINING FLOW RATES OF EXCRETED OR SECRETED BODY FLUIDS

The invention relates to an apparatus and method to determine and monitor the flow rates and volume of fluids excreted or secreted by the body. The invention achieves the above objects by providing an apparatus comprising; a measuring unit comprising a conduit made of a material having a low thermal conductivity and supporting at least two thermistors; an upstream thermistor serving as a compensation thermistor and a downstream thermistor located as far downstream as possible from said upstream thermistor and pre-heated to and kept at pre-defined temperature which is warmer than the fluid temperature to be metered; and means for applying small electric voltages to the thermistors to enable generation of an electric signal; and a control and display unit being operatively connected to the measuring unit. 1. An apparatus for determining the flow rate and amount of a selected secreted or excreted body fluid , comprising:a) a measuring unit comprising a conduit made of a material having a low thermal conductivity and supporting at least two thermistors; an upstream thermistor serving as a compensation thermistor and a downstream thermistor located as far downstream as possible from said upstream thermistor and pre-heated to a temperature which is warmer than the fluid temperature;b) means for applying constant small electric voltages to said thermistors to enable generation of electric signals, said signals flowing through said upstream thermistor being sufficiently low to prevent substantial heating of said thermistor; andc) a control and display unit being operatively connected to said measuring unit, said control unit including means for calculating the difference between the electrical resistance of said upstream and said downstream thermistors and then calculating the flow rate based on the electrical signal difference, the flow rate being a function of the body fluid flow rate and then calculating the accumulated amount of fluid based on the internal cross section ...

PORTABLE PULSEOXIMETER FOR A DIRECT AND IMMEDIATE AUTOMATED EVALUATION OF THE CARDIAC RHYTHM (REGULARITY) AND RELATED METHOD

A method and system of patient monitoring, the system performs short term acquisition of the plethysmographic waveform of a patient from a portable blood oxygenation level monitoring device and establishes whether the patient has an episode of Atrial Fibrillation (AF) or has a Normal Sinus Rhythm (NSR) or any other not-specific rhythm irregularity. Such classification is implemented directly in the device, suitable for at home use, and the result of the classification is displayed automatically using a three-state, traffic-light indicator. 15-. (canceled)7. A method according to wherein the step a) comprises:I) estimation of the time-occurrence of each beat from the pulseoximetric waveform;II) construction of the beat-to-beat series;III) beat-validation to reduce artifacts through morphological analysis of the ascendent and descendent tracts of a single pulse using a parametric modelling of the pulse waveform contour;IV) removal of beat intervals with values lower than 0.3 s and longer than 1.5 s.8. A method according to claim 7 , wherein each single pulse or heart beat in the pulse plethysmographic waveform is segmented into three sections claim 7 , a first section of the pulse being compared to a linear segment claim 7 , a third section of the pulse being compared to an exponential decay claim 7 , a similarity with linear and exponential function corresponding to said segment and decay being assessed using the goodness of R-squared fit.9. A method according to claim 8 , wherein the beat is categorized as artifact and neglected if the R-squared of said linear and exponential tracts are both lower than a reference level.12. A system according to claim 11 , wherein it comprises display means with a three-state light indicator.13. A system according to claim 11 , wherein it comprises means to detect artifacts claim 11 , said artifacts being rejected.14. A system according to claim 13 , wherein said means to detect artifacts are the CPU claim 13 , said CPU obtaining a ...

BODY FAT MEASUREMENT DEVICE

A body fat measurement device includes a plurality of electrodes including back area electrodes and upper limb electrodes, a body impedance measurement unit that measures a body impedance using the plurality of electrodes, a body composition information calculation unit that calculates a body fat mass based on the body impedance, a fitting belt for bringing the back area electrodes into contact with the surface of the measurement subject's back area in a pressurized state, and an upper limb unit that includes a gripping portion that can be gripped by the measurement subject's hand, the upper limb electrodes being provided in the gripping portion. The upper limb unit can be attached to and detached from the fitting belt. 1. A body fat measurement device comprising:a plurality of electrodes comprising back area electrodes for making contact with a surface of a back area that is an area on a back side of a measurement subject's trunk area, and upper limb electrodes for making contact with a surface of the measurement subject's upper limbs;a body impedance measurement unit for measuring a body impedance of the measurement subject's body using said plurality of electrodes;a body composition information calculation unit that calculates a body fat mass based on said body impedance measured by said body impedance measurement unit;a fitting belt for bringing said back area electrodes into contact with the surface of the measurement subject's back area in a pressurized state by being tightened around the measurement subject's trunk area; andan upper limb unit that includes comprising a gripping portion that can be gripped by the measurement subject's hand, said upper limb electrodes being provided in said gripping portion,wherein said upper limb unit can be attached to and detached from said fitting belt.2. The body fat measurement device according to claim 1 ,wherein said fitting belt comprises a first engagement member;wherein said upper limb unit includes comprises a ...

FAT MASS MEASUREMENT APPARATUS

A fat mass measurement apparatus includes an area detection unit that detects a predetermined position in a measurement subject's trunk area and detecting a predetermined area in the trunk area using the detected position; an electrode position setting unit that sets, on the body surface at the predetermined area detected by the area detection unit, a plurality of positions along the vertical direction of the trunk area for measuring the body impedance; an impedance measurement unit that measures the body impedance by bringing the impedance measurement electrodes into contact with each of the plurality of positions that have been set; and an abdominal area fat mass calculation unit that calculates a fat volume at the predetermined area based on the body impedances at each of the plurality of positions measured by the impedance measurement and the size of the trunk area at the predetermined area. 1. A fat mass measurement apparatus for measuring a fat mass in a body based on a body impedance measured by bringing impedance measurement electrodes into contact with a measurement subject's body surface , the apparatus comprising:a position detection means for detecting a predetermined position in a trunk area of the measurement subject;an area detection means for detecting a predetermined area in the trunk area using the position detected by said position detection means;an electrode position setting means for setting, on the body surface at said predetermined area detected by said area detection means, a plurality of positions along a vertical direction of the trunk area for measuring said body impedance;an impedance measurement means for measuring said body impedance by bringing said impedance measurement electrodes into contact with each of the plurality of positions set by said electrode position setting means; anda fat mass calculation means for calculating a fat mass of said predetermined area based on said body impedances at each of said plurality of positions ...

METHOD AND APPARATUS FOR DETERMINING A CENTRAL AORTIC PRESSURE WAVEFORM

A method is provided for determining a central aortic pressure waveform. The method includes: measuring two or more peripheral artery pressure waveforms; analyzing the signals so as to extract common features in the measured waveforms; and determining an absolute central aortic pressure waveform based on the common features. 1105.-. (canceled)106. A method for determining an absolute central aortic pressure waveform comprising:measuring peripheral artery pressure signals or related signals at more than one peripheral location in an arterial tree of a subject;modeling the arterial tree as a single input, multi-output system in which each output corresponds to one of the measured signals;analyzing, by a computing device having a processor, the measured signals so as to estimate a common input of the system to within an arbitrary scale factor; anddetermining, by the computing device, an absolute central aortic pressure waveform by scaling the estimated input based on the measured signals.107. The method of wherein channels of the single-input claim 106 , multi-output system model of the arterial tree are first estimated to within an arbitrary scale factor and then an inverse of the estimated channels is applied to the measured signals so as to reconstruct the common input to within an arbitrary scale factor.108. The method of wherein channels of the single-input claim 106 , multi-output system model of the arterial tree are characterized by linear and time-invariant impulse responses that are coprime.109. The method of wherein analyzing the measured signals further comprises applying multi-channel blind system identification to the measured signals to estimate parameters and order of the impulse responses and thereby estimate the impulse responses to within an arbitrary scale factor; and estimating the input of the system to within an arbitrary scale factor by deconvolution.110. The method of further comprising the representation of the impulse responses with a set of ...

BABY MONITORING MAT BASED ON FIBER OPTIC SENSOR

The present invention provides a baby monitoring mat having a sensor mat having a top mesh layer, a bottom mesh layer, and two flexible sheets and an optical cable, wherein the optical cable is routed across and sandwiched in between the top mesh layer and the bottom mesh layer, and the flexible sheets further sandwiched the top mesh layer and the bottom mesh layer in between forming sensing area across the flexible sheet surface; a light source for feeding light from one side of the optical cable; a photodiode for detecting light attenuation at the other end of the optical cable; a printed circuit board having a processor connected to the light source and the photodiode, wherein the processor operationally receives signals from the photodiode, the signals are processed to determine movements and breath counts. The signals are generated based on the light attenuation changes along the optical fiber cable detected by photodiode, the light attenuation changes are operationally caused by the optical fiber bending lost caused by the movements and breath. A method for monitoring baby on a mat is also provided. 1. A Baby Monitoring Mat , comprising:a sensor mat having a top mesh layer, a bottom mesh layer, and two flexible sheets and an optical cable, wherein the optical cable is routed across and sandwiched in between the top mesh layer and the bottom mesh layer, and the flexible sheets further sandwiched the top mesh layer and the bottom mesh layer in between forming sensing area across the flexible sheet surface;a light source for feeding light from one side of the optical cable;a photodiode for detecting light attenuation at the other end of the optical cable;a printed circuit board having a processor connected to the light source and the photodiode, wherein the processor operationally receives signals from the photodiode, the signals are processed to determine movements and breath counts,wherein the signals are generated based on the light attenuation changes along ...

Non-invasive cardiac output determination

A method of controlling a gas delivery apparatus including an apparatus controllable variable using an iterative algorithm to deliver a test gas (TG) for non-invasively determining a subject's pulmonary blood flow comprising iteratively generating and evaluating test values of a iterated variable based on an iterative algorithm in order output a test value of the iterated variable that meets a test criterion wherein iterative algorithm is characterized in that it defines a test mathematical relationship between the at least one apparatus controllable variable, the iterated variable and an end tidal concentration of test gas attained by setting the apparatus controllable variable, such that the iterative algorithm is determinative of whether iteration on the test value satisfies a test criterion or iteratively generates a progressively refined test value.

DILUTION APPARATUS, METHOD AND COMPUTER PROGRAM

An apparatus for determining a patient's circulatory fill status is adapted to provide a dilution curve and is capable to derive the ratio between the patient's global end-diastolic volume GEDV and the patient's intra thoracic thermo volume ITTV from the dilution curve. Further, a computer program for determining a patient's circulatory fill status has instructions adapted to carry out the steps of generating the dilution curve on basis of provided measurement data of dilution versus time, deriving the ratio between the patient's global end-diastolic volume GEDV and the patient's intra thoracic thermo volume ITTV from the dilution curve, and determining the patient's circulatory fill status on basis of the ratio between the patient's global end-diastolic volume GEDV and the patient's intra thoracic thermo volume ITTV, when the computer program is run on a computer. A method is also provided. 1. An apparatus for determining a patient's circulatory fill status comprising:a device configured to provide a dilution curve and configured to derive a ratio between a patient's global end-diastolic volume (GEDV) and a patient's intra thoracic thermo volume (ITTV), wherein the device is configured to determine a ratio between the patient's GEDV and ITTV as a function of a ratio between a median transit time (MDT) and a mean transit time (MTT), wherein the median transit time (MDT) is defined as being the point of time on which half of the dilution curve area is reached and the mean transit time (MTT) is defined as being the point of time on which a center of mass of the dilution curve area is located, and wherein the apparatus is capable of deriving the ratio between the median transit time (MDT) and the mean transit time (MTT) from the dilution curve.2. The apparatus of claim 1 , wherein the apparatus is configured to determine a linear relationship between the ratio between the patient's global end-diastolic volume (GEDV) and the patient's intra thoracic thermo volume (ITTV) ...

METHOD AND APPARATUS FOR OBTAINING AND PROCESSING BALLISTOCARDIOGRAPH DATA

A method and apparatus are provided for obtaining and processing ballistocardiograph data to determine a physiological condition of a subject. Ballistocardiograph data indicative of heart motion of the subject measured along a plurality of spatial axes by a sensor device which may comprise a three-axis accelerometer. The ballistocardiograph data is processed to determine processed data indicative of heart motion of the subject. Indications of physiological condition are determined based at least in part on the processed data. Processing may comprise aggregation of multidimensional data, determining magnitude of heart motion and derivative thereof, determining a thrust summation, determining an index value, outputting a report based on an index value, etc. Processing may be informed by operator input, such as a time window of interest or indications of interest. 1. An apparatus for determining information indicative of a subject's physiological condition , said apparatus comprising:a) a sensor device configured to obtain ballistocardiograph data indicative of heart motion of the subject measured along a plurality of spatial axes; andb) a computing device communicatively coupled to the sensor device and configured to receive the ballistocardiograph data therefrom, the computing device configured to determine, based on the ballistocardiograph data, processed data indicative of heart motion of the subject, the computing device further configured to determine one or more indications of the subject's physiological condition based at least in part on the processed data.2. The apparatus according to claim 1 , wherein the sensor device comprises a three-axis accelerometer.3. The apparatus according to claim 2 , wherein the sensor device comprises one or more analog-to-digital converters configured to convert data from the three-axis accelerometer to digital ballistocardiograph data.4. The apparatus according to claim 1 , wherein the ballistocardiograph data comprises time ...

SYSTEM AND METHOD FOR ESTIMATING UPPER AIRWAY RESISTANCE AND LUNG COMPLIANCE EMPLOYING INDUCED CENTRAL APNEAS

A method of estimating upper airway resistance or lung compliance of a patient is provided that includes inducing a central apnea in the patient, providing a known pressure stimulus comprising a flow of breathing gas having a known pressure level to the patient while the patient is experiencing the central apnea, determining a patient flow-related parameter, such as flow rate and/or flow volume, associated with the known pressure stimulus, and estimating the upper airway resistance or the lung compliance of the patient using the patient flow-related parameter using, for example and without limitation, an input-output system identification method. 1. A method of estimating upper airway resistance or lung compliance of a patient , comprising:inducing a central apnea in the patient;providing a known pressure stimulus comprising a flow of breathing gas having a known pressure level to the patient while the patient is experiencing the central apnea;determining a patient flow-related parameter associated with the known pressure stimulus; andestimating the upper airway resistance or the lung compliance of the patient using the patient flow-related parameter.2. The method according to claim 1 , wherein the patient flow-related parameter is a flow rate at the patient.3. The method according to claim 1 , wherein the patient flow-related parameter is a volume of flow at the patient.4. The method according to claim 1 , wherein the estimating employs an input-output system identification method.5. The method according to claim 4 , wherein the input-output system identification method is based on a single compartment lung model.6. The method according to claim 1 , wherein the inducing a central apnea in the patient comprises providing a central apnea inducing stimulus to the patient.7. The method according to claim 6 , wherein the inducing a central apnea further includes determining whether patient airflow has ceased claim 6 , and wherein the providing the known pressure ...

METHOD OF MANAGING A WEIGHT CONDITION IN AN ANIMAL

A methodology of managing a weight condition of a companion animal by determining body fat composition of the companion animal and an appropriate weight loss regimen based on the body fat percentage is provided. More specifically, described herein is a clinically useful tool and methodology to apply to over-weight and obese animals for use in managing a weight condition of the overweight or obese animal by determining the body fat percentage of the animal and providing a weight loss regimen. 1. A method of managing a weight condition in a companion animal comprising: using methods to determine the actual body percentage of body fat or lean body mass of a companion animal , using measurements of physical data of the companion animal to apply regression analysis based on the actual percentage of body fat or lean body mass , deriving one or more equations based on the regression analysis , to predict the percentage of body fat or lean body mass in the companion animal and using the predicted percentage of body fat or lean body mass to provide an effective weight loss regimen for the companion animal.2. The method of wherein the method to determine the actual body percentage or lean body mass of the companion animal is dual-energy X-ray absorptiometry.3. The method of wherein the companion animal is a cat.4. The method of wherein the one or more equations are two separate equations claim 1 , wherein the first equation is used for a companion animal having a body weight equal to or less than a threshold amount claim 1 , and the second equation is used for a companion animal having a body weight greater than a threshold amount.5. The method of wherein the companion animal is a dog and the threshold amount is forty pounds.6. The method of claim 1 , wherein the measurements of physical data comprise measurements of body weight (BW) claim 1 , cranial length (CL) claim 1 , cranial length*head circumference (CL×HC) claim 1 , head width (HW) claim 1 , hind leg center foot pad ...

OXIMETER AMBIENT LIGHT CANCELLATION

A pulse oximeter method and apparatus which provides (1) a notch filter at a distance between a modulation frequency and a common multiple of commonly used power line frequencies (50, 60, 100 and 120) and also (2) a demodulation frequency greater than a highest pulse rate of a person and lower than any harmonic of 50, 60, 100 or 120 Hz, to filter ambient light interference, while choosing an optimum demodulation frequency that avoids interference from the notch filter or from harmonics of the line interference. Also, ambient light for any low frequency interference, such as power line interference, is measured both before and after each of the light emitter wavelengths and the average of the ambient light is then subtracted from the detected signal. 1. A method for operating a pulse oximetry system , comprising:alternately generating light with a sensor at two wavelengths using a modulation frequency that is a predetermined distance from a common multiple of 50, 60, 100, and 120, where the predetermined distance is greater than a highest pulse rate of a person and lower than a distance of any harmonic of 50, 60, 100, or 120;receiving an analog sensor signal from the sensor that corresponds to received light;amplifying the analog sensor signal to provide an amplified analog sensor signal;modulating the amplified analog sensor signal with a sigma-delta modulator to provide a modulated signal;converting the modulated signal into a digital signal with a multiple bit analog-to-digital converter;decimating the digital signal with a decimator to provide a decimated signal;filtering the decimated signal with a digital filter to provide a filtered signal; andpreloading the decimator and digital filter with an estimate of a settled output value.2. The method of wherein processing the received light signal comprises digitizing the processed signal.3. The method of wherein the common multiple comprises 1200.4. The method of wherein the predetermined distance is between 5 and 20 ...

SYSTEM AND METHOD FOR ANALYZING A PATIENT STATUS FOR CONGESTIVE HEART FAILURE FOR USE IN AUTOMATED PATIENT CARE

A system and method for providing diagnosis and monitoring of congestive heart failure for use in automated patient care is described. At least one recorded physiological measure is compared to at least one other recorded physiological measure on a substantially regular basis to quantify a change in patient pathophysiological status for equivalent patient information. An absence, an onset, a progression, a regression, and a status quo of congestive heart failure is evaluated dependent upon the change in patient pathophysiological status. 1. A medical device providing physiometry for use in remote automated congestive heart failure patient management , comprising:one or more sensors to directly sense raw physiometry for a patient;sensing circuitry to regularly monitor and record the raw physiometry as collected device measures;memory to temporarily store the collected device measures pending interrogation by an externally interfaceable device; anda telemetry interface to provide access to the collected device measures, wherein derived device measures are thereafter determined to provide derivative physiometry based on the collected device measures and the collected and derived device measures quantify a pathophysiology indicative of congestive heart failure.2. The medical device of claim 1 , further comprising:programming parameters for the medical device, wherein the collected device measures are recorded subsequent to application of the programming parameters.3. The medical device of claim 1 , wherein the medical device comprises one of an implantable medical device and an external medical device.4. The medical device of claim 1 , wherein one or more of the collected and derived device measures are selected from the group comprising self referencing and and general population physiometric measures.5. A method for processing physiometry for use in remote automated congestive heart failure patient management claim 1 , comprising:identifying a patient enrolled in ...

Accurate time annotation of intracardiac ecg signals

A method for analyzing signals, including: sensing a time-varying intracardiac potential signal and finding a fit of the time-varying intracardiac potential signal to a predefined oscillating waveform. The method further includes estimating an annotation time of the signal responsive to the fit.

PULSE OXIMETRY SYSTEM

Systems and methods for estimating a saturation level of oxygen in hemoglobin (SpO2) are provided. In some aspects, a system includes a detector module configured to receive an oximeter output signal indicative of light absorption in a patient. The oximeter output signal alternates between infrared light components and red light components, and includes a first portion obtained at least partly during switching from at least one of the infrared components to at least one of the red components. The oximeter output signal also includes a second portion obtained at least partly during switching from at least one of the red components to at least one of the infrared components. The system also includes a processing module configured to estimate an SpO2 of the patient as a ratio between (i) a time derivative of the first portion and (ii) a time derivative of the second portion. 1. A system , for estimating a saturation level of oxygen in hemoglobin (SpO) , comprising: a first portion obtained at least partly during switching from at least one of the infrared components to at least one of the red components; and', 'a second portion obtained at least partly during switching from at least one of the red components to at least one of the infrared components; and, 'a detector module configured to receive an oximeter output signal indicative of light absorption in a patient, the oximeter output signal alternating between infrared light components and red light components and comprising{'sub': '2', 'a processing module configured to estimate an SpOof the patient as a ratio between (i) a time derivative of the first portion and (ii) a time derivative of the second portion.'}2. The system of claim 1 , wherein the oximeter output signal alternates between the infrared light components and the red light components according to a predetermined frequency.3. The system of claim 2 , wherein the time derivative of the first portion is with respect to a switching time duration claim 2 , ...

SYSTEM AND METHOD FOR ESTIMATING ELECTRICAL CONDUCTION DELAYS FROM IMMITTANCE VALUES MEASURED USING AN IMPLANTABLE MEDICAL DEVICE

Techniques are provided for estimating electrical conduction delays with the heart of a patient based on measured immittance values. In one example, impedance or admittance values are measured within the heart of a patient by a pacemaker or other implantable medical device, then used by the device to estimate cardiac electrical conduction delays. A first set of predetermined conversion factors may be used to convert the measured immittance values into conduction delay values. In some examples, the device then uses the estimated conduction delay values to estimate LAP or other cardiac pressure values. A second set of predetermined conversion factors may be used to convert the estimated conduction delays into pressure values. Techniques are also described for adaptively adjusting pacing parameters based on estimated LAP. 1. A system for estimating cardiac pressure within a patient using an implantable medical device , the system comprising:an immittance detection system operative to detect a value representative of electrical immittance within the heart of the patient; andan immittance-based electrical conduction delay estimation unit operative to estimate an electrical conduction delay in the heart of the patient from the value representative of immittance.2. The system of further including a conduction delay-based cardiac pressure estimation unit operative to estimate cardiac pressure within the patient from the estimated electrical conduction delay. This application is a Divisional application of and claims priority and other benefits from U.S. patent application Ser. No. 12/127,963 (Attorney Docket No. A08P3008), filed May 28, 2008, entitled “SYSTEM AND METHOD FOR ESTIMATING ELECTRICAL CONDUCTION DELAYS FROM IMMITTANCE VALUES MEASURED USING AN IMPLANTABLE MEDICAL DEVICE”, incorporated herein by reference in its entirety.This application claims priority on U.S. patent application Ser. No. 11/779,350, of Wenzel et al., filed Jul. 18, 2007, entitled, “System and ...

METHOD AND SYSTEM FOR NON-INVASIVELY MONITORING BIOLOGICAL OR BIOCHEMICAL PARAMETERS OF INDIVIDUAL

A system and method are presented for use in monitoring one or more conditions of a subject's body. The system includes a control unit which includes an input port for receiving image data, a memory utility, and a processor utility. The image data is indicative of data measured by a pixel detector array and is in the form of a sequence of speckle patterns generated by a portion of the subject's body in response to illumination thereof by coherent light according to a certain sampling time pattern. The memory utility stores one or more predetermined models, the model comprising data indicative of a relation between one or more measurable parameters and one or more conditions of the subject's body. The processor utility is configured and operable for processing the image data to determine one or more corresponding body conditions; and generating output data indicative of the corresponding body conditions. 1. A system for use in monitoring one or more conditions of a subject's body , the system comprising a control unit comprising:an input port for receiving image data measured by a pixel detector array and being in the form of a sequence of speckle patterns generated by a portion of the subject's body in response to illumination thereof by coherent light according to a certain sampling time pattern;a memory utility for storing one or more predetermined models, the model comprising data indicative of a relation between one or more measurable parameters and one or more conditions of the subject's body; and processing the image data and determining a spatial correlation function between successive speckle patterns in the sequence, and determining a time varying spatial correlation function in the form of a time-varying function of at least one feature of the correlation function, the time-varying spatial correlation function being indicative of a change of the speckle pattern over time;', 'selecting at least one parameter of the time-varying spatial correlation function, ...

MULTI-MODAL IMAGING OF BLOOD FLOW

The application features methods, devices, and systems for measuring blood flow in a subject. The computer-implemented methods include receiving functional magnetic resonance imaging (fMRI) data that provides information on at least one of volume or oxygenation of blood at one or more locations in a body over a first predetermined length of time. The methods also include receiving near-infrared spectroscopic (NIRS) imaging or measurement data representing at least one of blood concentration or oxygenation at a first portion of the body over a second predetermined length of time. The methods further include deriving, from the fMRI data corresponding to a second portion of the body, a time varying data set representing changes in blood oxygenation or volume or both blood oxygenation and volume at the second portion over the first predetermined length of time and determining, by a computing device, a time delay and a value of a similarity metric corresponding to a part of the spectroscopic imaging data that most closely matches the time varying data set. The time delay represents a difference between a first time in which blood flows from a third portion in the body to the first portion and a second time in which blood flows to the second portion from the third portion. The value of the similarity metric represents an amount of blood at the second portion. An estimate of a characteristic of at least one of blood flow or blood volume in the second portion at a given time is determined based on the time delay and the value of the similarity metric. 136-. (canceled)37. A computer-implemented method for measuring at least one of blood flow or volume in a subject , the method comprising:receiving functional magnetic resonance imaging (fMRI) data that provides information on at least one of volume or oxygenation of blood at one or more locations in a body over a first predetermined length of time;receiving spectroscopic measurement data representing at least one of blood ...

ULTRASOUND IMAGING APPARATUS AND METHOD OF DISPLAYING ULTRASOUND IMAGE

An ultrasound imaging apparatus and ultrasound image display method simultaneously obtain photo-acoustic information and elasticity information of a subject, and generate and display a single image having the photo-acoustic information and the elasticity information, thereby enhancing accuracy and efficiency of a diagnosis. The ultrasound imaging apparatus includes a probe to radiate light when stress is applied and when stress is not applied to the subject, and to receive a corresponding first acoustic wave signal and a second acoustic wave signal, a data acquisition unit to acquire first acoustic wave data and second acoustic wave data that each represent optical absorption rate information about the subject, an elasticity information generating unit to calculate elasticity information about the subject, an image generating unit to generate a single image having both of the optical absorption rate information and the calculated elasticity information, and a display unit to display the generated image. 1. An ultrasound imaging apparatus , comprising:a probe configured to radiate light to a subject when a stress is applied to the subject and when a stress is not applied to the subject, and configured to receive a first acoustic wave signal generated when the stress is not applied to the subject and a second acoustic wave signal generated when the stress is applied to the subject;a data acquisition unit configured to acquire first acoustic wave data and second acoustic wave data which include optical absorption rate information about the subject, based on the first acoustic wave signal and second acoustic wave signal;an elasticity information generating unit configured to calculate elasticity information about the subject based on the first acoustic wave data and the second acoustic wave data;an image generating unit configured to generate a single image having the optical absorption rate information and the calculated elasticity information; anda display unit ...

BIO-DIAGNOSTIC TESTING SYSTEM AND METHODS

An implantable diagnostic device in accordance with the present disclosure includes a probe assembly that can be implemented in a variety of ways. A few example implementations include: a needle inside which is located a bio-sensor chip (the needle being insertable into a human being); a compact package containing the bio-sensor chip (the compact package configured for placement inside a catheter); or a silicon-based bio-sensor package configured for insertion into a vein. 1. A bio-diagnostic system comprising:a probe assembly configured for insertion into an animate object, the probe assembly comprising:an optical waveguide configured for propagating a light beam; andan optical resonator incorporating a capture agent placed upon a binding site that is exposed to a fluid, the optical resonator configured to receive at least a portion of the propagated light beam and generate therefrom, a first resonant wavelength when no binding reaction is present at the binding site, and a second resonant wavelength when a binding reaction is present at the first binding site, the binding reaction modifying a refractive index of the optical resonator.2. The bio-diagnostic system of claim 1 , wherein the probe assembly is at least one of: a) a needle comprising a first bio-sensor chip that includes the optical waveguide and the first optical resonator claim 1 , b) a catheter comprising a second bio-sensor chip that includes the optical waveguide and the first optical resonator claim 1 , or c) a third bio-sensor chip configured for insertion into the vein claim 1 , the third bio-sensor chip comprising the optical waveguide and the first optical resonator.3. The bio-diagnostic system of claim 2 , wherein at least one of the needle or the catheter is a part of an intravenous (IV) apparatus.4. The bio-diagnostic system of claim 2 , wherein the needle has a sub-mm diameter.5. The bio-diagnostic system of claim 4 , wherein the fluid is one of: blood claim 4 , lymphatic fluid claim 4 , ...

Apparatus and program for evaluating biological function

An apparatus and a program are provided which are capable of simultaneously measuring, evaluating, imaging and displaying the biological function of sites with different biological functions, such as the brain and the muscle, different parts of the brain or different muscle locations, using near-infrared spectroscopy. In an apparatus for evaluating biological function K, physiological indices, including parameters derived from changes in deoxyhemoglobin concentration and changes in oxyhemoglobin concentration, are calculated by a calculating part of a controller. To measure simultaneously, evaluate, image and display the biological functions of sites with different biological function, such as the brain and the muscle, different parts of the brain or different muscle locations, these physiological indices from different sites of the living body are adjusted in such a way that they can be compared with each other by the calculating part and displayed by a display part. 1. An apparatus for evaluating biological function that is an apparatus for evaluating biological function having a plurality of living body probes for irradiating light to and receiving emitted light from a plurality of sites with different biological functions of a living body , and an apparatus body for entering light information detected by means of said plurality of living body probes and performing calculation , control and memory operations , and utilizing the near-infrared spectroscopy method , wherein said plurality of sites of said living body with different biological functions include at least a brain site and a muscle site , wherein said apparatus body comprising:a calculating part for calculating amounts of change in oxyhemoglobin concentration and amounts of change in deoxyhemoglobin concentration and/or physiological indices including a variety of parameters derived from the relationships between them, based on light information from said plurality of living body probes;an adjusting ...

SYSTEMS AND METHODS FOR PROCESSING SENSOR DATA

Systems and methods for processing sensor data are provided. In some embodiments, systems and methods are provided for calibration of a continuous analyte sensor. In some embodiments, systems and methods are provided for classification of a level of noise on a sensor signal. In some embodiments, systems and methods are provided for determining a rate of change for analyte concentration based on a continuous sensor signal. In some embodiments, systems and methods for alerting or alarming a patient based on prediction of glucose concentration are provided. 1. A method for generating analyte measurements of a host , the method comprising:generating sensor data during a first time period using an analyte sensor coupled to a sensor electronics unit, wherein the sensor electronics unit is adhered to a body of a host;receiving, using a receiver in wireless communication with the sensor electronics unit, a reference analyte value generated by a reference analyte monitor;responsive to receiving the reference analyte value, determining a first estimated analyte concentration value to display using a first algorithm, wherein determining the first estimated analyte concentration to display includes using the reference analyte value in a first algorithm;determining a second estimated analyte concentration value to display using the reference analyte value and the sensor data for the first time period in a second algorithm that is different from the first algorithm; anddisplaying, on a display of the receiver, a numerical analyte value selected from the first estimated analyte value and the second estimated analyte value, wherein the first estimated analyte concentration value is selected as the displayed numerical value until the second estimated analyte concentration is available, and subsequently selecting the second estimated analyte concentration value to be the displayed numerical value.2. The method of claim 1 , wherein the sensor data for the first time period is not used ...

SYSTEM FOR MONITORING AND MANAGING BODY WEIGHT AND OTHER PHYSIOLOGICAL CONDITIONS INCLUDING ITERATIVE AND PERSONALIZED PLANNING, INTERVENTION AND REPORTING CAPABILITY

A nutrition and activity management system is disclosed that monitors energy expenditure of an individual through the use of a body-mounted sensing apparatus. The apparatus is particularly adapted for continuous wear. The system is also adaptable or applicable to measuring a number of other physiological parameters and reporting the same and derivations of such parameters. A weight management embodiment is directed to achieving an optimum or preselected energy balance between calories consumed and energy expended by the user. An adaptable computerized nutritional tracking system is utilized to obtain data regarding food consumed, Relevant and predictive feedback is provided to the user regarding the mutual effect of the user's energy expenditure, food consumption and other measured or derived or manually input physiological contextual parameters upon progress toward said goal. 1278.-. (canceled)279. A system for monitoring human physiological parameters and providing status information therefor , the system comprising: an apparatus adapted for placement on the human body which: (a) receives at least one of (i) detected and (ii) manually input data related to a first human physiological parameter; (b) directly detecting at least a second human physiological parameter; and (c) providing status information with respect to the mutual effect of changes of said first and second human physiological parameters upon each other.280. A system as described in claim 279 , wherein said apparatus is a sensor device for mounting on the human body.281. A system as described in claim 280 , wherein said sensor device is an armband sensor device for mounting on the upper arm of the human body.282. A system as described in claim 280 , wherein said sensor device further comprises at least one sensor for detecting at least one of said first and second human physiological parameters.283. A system as described in claim 280 , wherein said at least one sensor further comprises at least one of ...

SYSTEM FOR MONITORING AND MANAGING BODY WEIGHT AND OTHER PHYSIOLOGICAL CONDITIONS INCLUDING ITERATIVE AND PERSONALIZED PLANNING, INTERVENTION AND REPORTING CAPABILITY

A nutrition and activity management system is disclosed that monitors energy expenditure of an individual through the use of a body-mounted sensing apparatus. The apparatus is particularly adapted for continuous wear. The system is also adaptable or applicable to measuring a number of other physiological parameters and reporting the same and derivations of such parameters. A weight management embodiment is directed to achieving an optimum or preselected energy balance between calories consumed and energy expended by the user. An adaptable computerized nutritional tracking system is utilized to obtain data regarding food consumed, Relevant and predictive feedback is provided to the user regarding the mutual effect of the user's energy expenditure, food consumption and other measured or derived or manually input physiological contextual parameters upon progress toward said goal. 1278-. (canceled)279. A system for monitoring and managing body weight comprised of:a body mounted detection apparatus for detecting data indicative of human status parameters selected from the group consisting of energy expenditure and nutritional parameters of an individual; anda monitoring unit in communication with said detection apparatus for receiving at least one of (i) manually input and (ii) detected human status parameter data and manipulating said data to provide feedback with respect to the mutual effect of changes in said human status parameters upon each other.280. A system as described in claim 279 , wherein said body mounted detection apparatus comprises at least one sensor for detecting at least one of said human status parameters.281. A system as described in claim 280 , wherein said body mounted detection apparatus is an armband sensor device.282. A system as described in claim 280 , wherein said body mounted detection apparatus further comprises at least one sensor for detecting contextual parameters.283. A system as described in claim 282 , further comprising at least one ...

Activity Monitoring Systems and Methods of Operating Same

The present inventions, in one aspect, is an activity monitoring system comprising a fixture having size/shape adapted to couple to a location on the user's body and a particular signature; and a portable monitoring device adapted to detect the fixture's particular signature. The monitoring device includes a housing that is adapted to engage the fixture; an activity sensor, disposed in the housing, to detect activity of the user and to generate data which is representative of the activity of the user; and processing circuitry, disposed in the housing, to calculate an activity-related quantity of the user, wherein the processing circuitry determines the monitoring device is engaging the fixture by detecting the fixture's particular signature and calculates the activity-related quantity. 1. An activity monitoring system comprising:a plurality of fixtures, wherein each fixture includes a physical size and shape that is adapted to couple to an associated location on the body of the user; a housing to separately and physically engage each fixture;', 'an activity sensor, disposed in the housing, to detect activity of the user and, in response thereto, to generate data which is representative of the activity of the user; and', automatically determines a particular fixture of the plurality of fixtures is physically engaging the portable monitoring device, and', 'calculates at least one activity-related quantity of the user which is associated with the particular fixture., 'processing circuitry, disposed in the housing and coupled to the activity sensor, to calculate one or more activity-related quantities of the user using the data which is representative of the activity of the user, wherein the processing circuitry], 'a portable monitoring device adapted to separately and physically engage each fixture of the plurality of fixtures, the portable monitoring device including2. The activity monitoring system of wherein:at least one fixture of the plurality of fixtures includes ...

MRI THERMAL IMAGING OF WATER TISSUE AND FAT TISSUE USING TRANSVERSE RELAXOMETRY DATA AND PROTON RESONANCE FREQUENCY SHIFT DATA

An apparatus () comprising a magnetic resonance imaging system (), the magnetic resonance imaging system comprising: a magnet () adapted for generating a magnetic field for orientating the magnetic spins of nuclei of a subject () located within an imaging volume (); a radio frequency transceiver () adapted for acquiring magnetic resonance data () using a radio frequency coil (); a computer system () comprising a processor (), wherein the computer system is adapted for controlling the apparatus; and a memory () containing machine readable instructions (), wherein execution of the instructions cause the processor to perform the steps of: acquiring () magnetic resonance data using the magnetic resonance imaging system, wherein the magnetic resonance data comprises transverse relaxometry data, and calculating () the temperature of the subject within a temperature measurement volume () in accordance with the transverse relaxometry data. 1. An apparatus comprising a magnetic resonance imaging system , the magnetic resonance imaging system comprising:a magnet adapted for generating a magnetic field for orientating the magnetic spins of nuclei of a subject located within an imaging volume;a radio frequency transceiver adapted for acquiring magnetic resonance data using a radio frequency coil;a magnetic field gradient coil adapted for spatial encoding of the magnetic spins of nuclei within the imaging volume;a magnetic field gradient coil power supply adapted for supplying current to the magnetic field gradient coil;a computer system comprising a processor, wherein the computer system is adapted for controlling the apparatus; and acquiring magnetic resonance data using the magnetic resonance imaging system, wherein the magnetic resonance data comprises transverse relaxometry T2 or T2 star data, as well as proton resonance frequency shift data, wherein at least the transverse relaxometry T2 or T2 star data is acquired using a turbo spin echo (TSE) sequence, and', 'calculating ...

APPARATUS FOR EVALUATING VASCULAR ENDOTHELIAL FUNCTION

An apparatus for evaluating a vascular endothelial function, includes: a cuff pressure controlling unit configured to perform continuous pressure stimulation on a part of a body of a subject for a predetermined time, by using a cuff adapted to be wrapped around the part of the body of the subject; a cuff pressure detecting unit configured to detect a cuff pressure from an output of a pressure sensor connected to the cuff; a pulse wave detecting unit configured to detect a pulse wave from the output of the pressure sensor; and an analyzing unit configured to evaluate the vascular endothelial function by comparing vessel viscoelastic indexes which are obtained from the pulse wave detected in two of zones before, during, and after the pressure stimulation, and which exclude an amplitude of the pulse wave. 1. An apparatus for evaluating a vascular endothelial function , the apparatus comprising:a cuff pressure controlling unit configured to perform continuous pressure stimulation on a part of a body of a subject for a predetermined time, by using a cuff adapted to be wrapped around the part of the body of the subject;a cuff pressure detecting unit configured to detect a cuff pressure from an output of a pressure sensor connected to the cuff;a pulse wave detecting unit configured to detect a pulse wave from the output of the pressure sensor; andan analyzing unit configured to evaluate the vascular endothelial function by comparing vessel viscoelastic indexes which are obtained from the pulse wave detected in two of zones before, during, and after the pressure stimulation, and which exclude an amplitude of the pulse wave.2. The apparatus according to claim 1 , whereinthe vessel viscoelastic indexes which exclude the amplitude of the pulse wave are one of velocities, areas, accelerations, waveform heights, and peak time periods of the pulse wave detected in the two of zones.3. The apparatus according to claim 1 , whereinthe pressure stimulation is pressurization at a ...

METHOD AND SYSTEM FOR DETECTING RESPIRATORY INFORMATION

The invention proposes a method of detecting respiratory information of a user. The method comprises a step of instructing the user to perform on a device a movement reflecting his respiratory action; a step of generating by said device, a signal reflecting said movement; and a step of deriving the user's respiratory information from said signal. By using this method, the respiratory information is easily detected without attaching any sensor on the user's chest. 1. A method of detecting respiratory information of a user , comprising the steps of:instructing the user to perform on a device a movement reflecting his respiratory action;generating, by said device, a signal reflecting said movement;deriving the user's respiratory information from said signal.3. A method according to claim 2 , wherein the variation period of said part of the signal is within a predefined range.4. A method according to claim 1 , said method further comprising a step of providing said derived respiratory information to the user.5. A method according to claim 1 , said method further comprising a step of providing a breathing instruction to the user according to a predefined requirement.7. A system for detecting respiratory information of a user claim 1 , comprising:a first unit for instructing the user to perform on a device a movement reflecting his respiratory action;a device being adapted to generate a signal reflecting said movement;a second unit for deriving the user's respiratory information from said signal.8. A system according to claim 7 , said system further comprising a third unit for selecting part of said signal having periodical variation; wherein said user's respiratory information is derived from said part of the signal.9. A system according to claim 7 , wherein said first unit comprises at least one of the following devices:a video display device;an audio playing device.10. A system according to claim 7 , said device comprising a deformable object and a sensor for detecting ...

Coil System and Method for Obtaining Volumetric Physiological Measurements

A coil device is provided having a member adapted to extend around and conform to an outer surface of a subject and a conductor adapted to extend only once around a first portion of the subject. The coil device can be positioned about the subject in order to measure a volume of the subject. When placed about the subject in the presence of a relatively homogeneous magnetic field, the conductor can generate a signal indicative of a volume of the first portion of the subject. The coil device may also include two or more conductors separately generating signals indicating volumes of two or more corresponding portions of the subject. In some cases the coil device includes associated authorization data that can limit use of the coil device. Systems and methods incorporating the coil device are also provided. 148-. (canceled)49. A system for measuring volume , the system comprising:an electromagnet configured to produce a magnetic field;a conductor configured to cover a portion of a subject for which a volumetric measurement is desired, the conductor configured to extend only once around the subject in a first direction and having a width generally perpendicular to the first direction, wherein upon placement of the conductor in the magnetic field the conductor is configured to produce a signal representing an average cross-sectional area, averaged over the width of the conductor, of the portion of the subject; anda control system configured to determine a volume of the portion of the subject based on the signal produced by the conductor.50. The system of claim 49 , wherein the magnetic field is a time-varying magnetic field.51. The system of claim 50 , wherein the magnetic field has a coefficient of variation of less than five percent throughout a spatial volume that encompasses the conductor when the conductor is placed in the magnetic field.52. The system of claim 49 , wherein the electromagnet is configured to be positioned entirely above the conductor when the ...

BLOOD GLUCOSE MEASUREMENT METHOD USING BLOOD GLUCOSE METER HAVING STEP COUNTER FUNCTION

The present invention provides a blood glucose measurement method using a blood glucose meter having a step counter function. In the blood glucose measurement method, a blood glucose level is measured in blood glucose measurement mode. The measured blood glucose level is configured in a form of data, the data is stored in a control unit, and the measured blood glucose level is displayed on a display unit under control of the control unit. Current mode is switched to step counting operation mode. The number of steps taken by a user is counted in the step counting operation mode and a count result is displayed on the display unit. 1. A blood glucose measurement method using a blood glucose meter having a step counter function , comprising:displaying a selection window for blood glucose measurement mode and step counting operation mode;selecting the blood glucose measurement mode from the selection window; measuring a blood glucose level in the blood glucose measurement mode;configuring the measured blood glucose level in a form of data, storing the data in a control unit, and displaying the measured blood glucose level on a display unit under control of the control unit;selecting the step counting operation mode from the selection window;counting a number of steps taken by a user in the step counting operation mode; andstoring a count result in the control unit and displaying the count result on the display unit,wherein a blood glucose level and an amount of exercise are individually measured depending on selection of the mode.2. A blood glucose measurement method using a blood glucose meter having a step counter function , comprising:measuring a blood glucose level in blood glucose measurement mode;configuring the measured blood glucose level in a form of data, storing the data in a control unit, and displaying the measured blood glucose level on a display unit under control of the control unit;switching current mode to step counting operation mode; andcounting a ...

Multiple wavelength sensor emitters

A physiological sensor has light emitting sources, each activated by addressing at least one row and at least one column of an electrical grid. The light emitting sources are capable of transmitting light of multiple wavelengths and a detector is responsive to the transmitted light after attenuation by body tissue.

APPARATUS FOR DETECTING AN APNEA/HYPOPNEA CONDITION

While remarkably reducing the botheration and burden on the subject, an apnea/hypopnea condition can be detected correctly and easily, and the type of the condition can be identified. A detecting apparatus for detecting an apnea/hypopnea condition of a living body, includes: an electric current applying electrode section to supply an electric current via electrodes into a cervical region of the living body; a measurement electrode section to measure an impedance of the cervical region by the electric current; an analysis section which detects an apnea/hypopnea condition based on the measured impedance; and an output section which outputs the result of detection. 1. A detecting apparatus for detecting an apnea/hypopnea condition of a living body , including:an electric current applying electrode section configured to supply an electric current via electrodes into a cervical region of the living body;a measurement electrode section configured to measure impedance of the cervical region by the electric current;an analysis section configured to detect an apnea/hypopnea condition based on the measured impedance; andan output section configured to output the result of detection.2. The detecting apparatus according to claim 1 , wherein the detecting apparatus further includes a respiration sensor which is placed on a region of the living body other than the cervical region claim 1 , and configured to output a signal caused by respiration or respiratory effort of the living body claim 1 , andthe analysis section is configured to identify types of the apnea/hypopnea condition based on the measured impedance and the output signal of the respiration sensor.3. The detecting apparatus according to claim 2 , whereinthe output section is configured to visualize the identification result.4. The detecting apparatus according to claim 2 , wherein the analysis section is configured to identify whether the living body is in an obstructive apnea/hypopnea condition or a central apnea/ ...

METHOD AND APPARATUS FOR MONITORING THE RESPIRATION ACTIVITY OF A SUBJECT

The invention relates to a method for monitoring the respiration activity of a subject, comprising the acquisition of a sensor signal of at least one Doppler-Radar sensor representing the respiration activity of a subject, the transformation of the sensor signal into a transformation signal being a series according to Formula (I) where ais a set of predetermined constant coefficients specific for one individual subject, and processing the transformation signal S(t). The transformation signal can be analysed with basic signal processing techniques that are applied in the field of inductive plethysmography. The invention is further related to a corresponding monitoring system. 2. The method according to claim 1 , characterized in that the set of coefficients ais taken from a look-up table.3. The method according to claim 2 , characterized in that the look-up table contains a plurality of different sets of coefficients a.4. The method according to claim 3 , characterized in that the subject is identified claim 3 , and one corresponding set of coefficients ais chosen from the plurality of sets of coefficients aaccording to the result of the identification.6. The method according to claim 1 , characterized in that D(t) is the sum of the sensor signals D(t) claim 1 , i=1 to n from n sensors.7. The method according to claim 1 , characterized in that a plurality of sensor signals D(t) claim 1 , i=1 to n is acquired from a plurality of n sensors claim 1 ,{'sub': 'k', 'and one set of coefficients ais determined for each one of these n sensors.'}1018. System according to claim 9 , characterized by a plurality of Doppler-Radar sensors () disposed at different positions within a measurement range.1120. System according to claim 10 , characterized in that said sensor transformation unit () is provided for transforming a sensor signal D(t) of each sensor i into a transformation signal S(t) and to summarize the resulting transformation signals S(t) to a summarized transformation ...

BODY CONDITION INFORMATION PROCESSING APPARATUS, NON-TRANSITORY COMPUTER READABLE RECORDING MEDIUM, AND METHOD FOR PROCESSING BODY CONDITION INFORMATION

A condition information processing apparatus (A) includes: an obtaining section () that obtains information relating to a bioelectrical impedance measured by means of impressing an alternating current of a predetermined frequency to a body surface of a user. An operating section () calculates an index relating to a body condition on the basis of the information relating to the bioelectrical impedance. 1. A condition information processing apparatus comprising:an obtaining section adapted for obtaining information relating to a bioelectrical impedance measured by means of impressing an alternating current of a predetermined frequency to a body surface of a user; andan operating section adapted for calculating an index relating to a body condition on the basis of the information relating to the bio electrical impedance.2. The condition information processing apparatus according to claim 1 , further comprising a condition estimating section adapted for estimating the body condition on the basis of a newly calculated index relating to the body condition and a past index relating to the body condition recorded as a measurement history.3. The condition information processing apparatus according to claim 1 , further comprising:a pair of current applying electrodes that is capable of contacting the body surface;a pair of voltage measuring electrodes that is capable of contacting the body surface;an alternating current applying section adapted for applying an alternating current to the current applying electrodes;a frequency setting section adapted for setting a predetermined frequency as a frequency of the alternating current impressed by the alternating current applying section; anda voltage measuring section adapted for measuring a voltage at the time of impressing the alternating current of the predetermined frequency,wherein the obtaining section obtains either of the voltage measured by the voltage measuring section and the bioelectrical impedance as the information ...

DEVICE AND METHOD FOR DETERMINING A FERTILE PHASE OF A WOMAN BY ASCERTAINING A CO2 PARTIAL PRESSURE IN A RESPIRATORY GAS OF THE WOMAN

The invention relates to a device () for determining a fertile phase of a woman by ascertaining a COpartial pressure in a respiratory gas of the woman in several consecutive breaths, comprising an inlet for receiving the respiratory gas, and an outlet, a sample chamber (), into which the respiratory gas can be conducted, a measuring module () with a measuring element () with which a COconcentration in the respiratory gas in the sample chamber () can be measured, optionally a pressure sensor () for measuring an air pressure, a processor () for processing measured data obtained by means of the measuring module () and the pressure sensor (), and at least one output unit () for outputting a result of the measured data. So that the method can be carried out by a woman herself quickly and nevertheless with high precision, it is provided according to the invention that the device () is embodied as a hand-held device and an algorithm is stored in the processor (), with which with a measurement based on several immediately consecutive breaths a predetermined reproducibility criterion regarding an end expiratory COpartial pressure of the respiratory gas can be tested, wherein, if the reproducibility criterion is met, the at least one output unit () outputs and/or signals and/or displays whether a fertile phase applies. Furthermore, the invention relates to a method for determining a fertile phase of a woman by ascertaining an end expiratory COpartial pressure in a respiratory gas and comparison of the measured data thus obtained with measured data in the follicle phase outside the fertile phase. 1. A device for determining a fertile phase of a woman by ascertaining a COpartial pressure in a respiratory gas of the woman in several consecutive breaths , comprising an inlet for receiving the respiratory gas , and an outlet , a sample chamber , into which the respiratory gas can be conducted , a measuring module with a measuring element with which a COconcentration in the ...

VIVO DETERMINATION OF ACIDITY LEVELS

A bolus for use in a ruminant animal's reticulum includes a cavity () configured to receive ruminal fluids present in the stomach. The cavity has walls () of a dielectric material and is encircled by a coil member (), which is configured to subject the ruminal fluids to an electro-magnetic field. A Sensor element () measures the electromag-netic field's influence on the ruminal fluids and thus register an electromagnetic property representative of an acidity level of said fluids. A transmitter () transmits a wireless output signal (SD) reflecting the acidity measure. 113-. (canceled)14100. A bolus for introducing into a ruminant animal's (A) reticulum (R) and for ongoing measurement of an acidity level of an animal's stomach fluids , the bolus () comprising:{'b': '100', 'a housing () having an outermost surface exterior wall;'}{'b': 1', '2', '110, "a cavity defined by a portion of the exterior wall of the housing, the cavity (C, C) having a wall of dielectric material and at least a first opening for receiving ruminal fluids into the cavity, the wall defining a dielectric conduit (), the first opening being an unobstructed opening freely allowing the ruminal fluids from the animal's (A) reticulum (R) to be received into the cavity;"}{'b': '310', 'a power generator () that generates electric power within a spectral range;'}{'b': 120', '110', '120, 'a sensor coil () encircling the dielectric conduit () and powered by the power generator, the sensor coil () configured to subject the received ruminal fluids (L) within the cavity to an electromagnetic field (B) within the spectral range;'}{'b': 320', '120, 'a processor () connected to the sensor coil () to measure, under influence of the electromagnetic field (B), an electromagnetic property (z) of the ruminal fluids (L),'}{'b': '320', 'sub': 'pH', 'wherein from the measure of the electromagnetic property (z), the processor () determines an acidity measure (M) of an acidity level of the ruminal fluids (L); and'}{'b': 410 ...

SINGLE INJECTION METHODS FOR OBTAINING CONDUCTANCE MEASUREMENTS WITHIN LUMINAL ORGANS USING IMPEDANCE DEVICES

Single injection methods for obtaining conductance measurements within luminal organs using impedance devices. In at least one method embodiment, the method is performed by introducing at least part of an impedance device into a mammalian luminal organ, the impedance device comprising an elongated body and a detector positioned along the elongated body, obtaining conductance measurements indicative of a fluid native to the mammalian luminal organ and indicative of a fluid injection while the detector is present within and outside of the lumen of the outer sheath, and calculating a size parameter of the mammalian luminal organ based in part upon some of the obtained conductance measurements. 1. A method for obtaining one or more conductance measurements using an impedance device , the method comprising the steps of:introducing at least part of an impedance device into a mammalian luminal organ, the impedance device comprising an elongated body and a detector positioned along the elongated body;obtaining a first conductance measurement using the detector while the detector is surrounded by an outer sheath surrounding at least part of the impedance device, the first conductance measurement indicative of a fluid native to the mammalian luminal organ present within a lumen of the outer sheath;obtaining a second conductance measurement using the detector while the detector is surrounded by the outer sheath, the second conductance measurement indicative of a first injection of a first solution of a first compound through the lumen of the outer sheath;moving the impedance device and/or the outer sheath relative to one another so that the outer sheath no longer surrounds the detector;obtaining a third conductance measurement using the detector, the third conductance measurement indicative of the fluid native to the mammalian luminal organ;obtaining a fourth conductance measurement using the detector, the fourth conductance measurement indicative of a second injection of the ...

MEDICAL FINDING SYSTEM WITH CONTROL MODULE FOR IMAGE ACQUISITION

In a finding system, a control system and a computer-implemented method to assess medical images, within the scope of a finding workflow a control module can be activated via which the user can enter control data at the finding system. The control data are automatically converted into control commands, which are transmitted to the acquisition system for execution. The acquisition system is expanded by an expansion module in order to transmit process data and status data to the finding system. 1. A computerized medical finding system to assist medical images , comprising:a computer;a monitor in communication with said computer;a user interface in communication with said computer;said computer comprising an acquisition system interface configured to place said computer in communication with a medical image data acquisition system that is located remote from said computer, in order to import into said computer, from said medical image data acquisition system, image data acquired by operation of said medical image data acquisition system operated according to first control commands executed by a control unit of said medical image data acquisition system;said computer being configured to display a medical image at said monitor corresponding to said medical image data;said computer being configured to receive control data, entered into said computer via said user interface, that describe operation of said medical image data acquisition system to acquire new medical image data that will produce a new medical image that differs from the medical image displayed at said monitor;said computer being configured to automatically convert said control data into new control commands in a form executable by said control unit of said medical image data acquisition system, and to transmit said new control commands directly and automatically to said medical image data acquisition system via said acquisition system interface; andsaid computer being configured to receive status data, via ...

Intrinsic Frequency Hemodynamic Waveform Analysis

Hardware and software methodology are described for cardiac health measurement. Hemodynamic waveforms variously acquired for a subject are analyzed to calculate or approximate intrinsic frequencies in two domains in two domains across the Dicrotic Notch. The intrinsic frequencies provide metrics/measures that correlate to the cardiac health of the subject. The systems may be used for monitoring a condition and/or is diagnosis. Exemplary uses include identifying (diagnosing) the presence of arrhythmia, heat failure, atrial fibrillation, aneurysms, vessel stenosis or aortic valve dysfunction and the necessity for valve replacement and/or monitoring congestive heart failure progression, together with identifying the acute need for hospitalization in connection with daily testing for any such condition. 1. A system for acquiring and analyzing a hemodynamic waveform of a subject , the system comprising:an optical scanner, the scanner adapted to capture a signal corresponding to a hemodynamic waveform; and{'sub': 1', '2, 'at least one computer processor connected to the scanner by a wired or wireless connection, wherein the computer processor is adapted to receive the signal for the hemodynamic waveform, determine a Dicrotic Notch using the signal, calculate first and second intrinsic frequencies (ω, ω) on each side of the Dicrotic Notch for the waveform, and output a signal corresponding to intrinsic frequencies results.'}2. A system for acquiring and analyzing a hemodynamic waveform of a subject , the system comprising:an ultrasound scanner, the scanner adapted to capture a signal corresponding to a hemodynamic waveform; and{'sub': 1', '2, 'at least one computer processor connected to the scanner by a wired or wireless connection, wherein the computer processor is adapted to receive the signal for the hemodynamic waveform, determine a Dicrotic Notch using the signal, calculate first and second intrinsic frequencies (ω, ω) on each side of the Dicrotic Notch for the ...

METHODS AND APPARATUS FOR DETERMINING ARTERIAL PULSE WAVE VELOCITY

Methods are presented for determining pulse transit time (PTT) and/or pulse wave velocity (PWV) of a subject by application of parametric system identification to proximal and distal arterial waveforms. The two waveforms are measured from the subject. A system is defined that relates the proximal arterial waveform to the distal arterial waveform (or vice versa) in terms of the unknown parameters of a parametric mathematical model. The model parameters are determined from the measured waveforms using system identification. PTT between the proximal and distal arterial sites is then determined from the system model. PWV may also be determined by dividing the distance between measurement sites (D) by PTT. 126-. (canceled)27. A method for determining an arterial pulse transit time of a subject , comprising:measuring a proximal waveform indicative of the arterial pulse at a proximal site of the subject;measuring a distal waveform indicative of the arterial pulse at a distal site of the subject;defining a dynamic system that relates one of the waveforms to the other waveform in terms of unknown parameters of a parametric mathematical model that assumes a specific structure for the system;determining the unknown parameters of the mathematical model from the measured proximal waveform and the measured distal waveform; anddetermining a pulse transit time between the proximal site and the distal site from the mathematical model.28. The method of further comprises determining a distance between the proximal and distal sites and determining a pulse wave velocity by dividing the distance by the pulse transit time.29. The method of further comprises determining the unknown parameters by fitting one of the proximal waveform or the distal waveform to the other waveform.30. The method of wherein the mathematical model is a parametric physical tube-load model transfer function in which the pulse transit time is an explicit parameter of the model.31. The method of wherein the waveforms ...

ELECTRONIC SPHYGMOMANOMETER FOR MEASURING BLOOD PRESSURE AND PULSE

An electronic sphygmomanometer includes a cuff including an air bladder, a pressure sensor, an artery volume sensor, and a computation device. The computation device includes an inner pressure control section, a volume sensor signal receive section for receiving a pulse wave signal detected by the artery volume sensor, a pressure sensor signal receive section for receiving a pressure pulse wave signal superimposed on the inner pressure of the air bladder and detected by the pressure sensor, a judgment section for choosing either the pulse wave signal or the pressure pulse wave signal as a signal for calculating pulse rate of the patient during a period when the inner pressure of the air bladder is increased and/or decreased by the inner pressure control section, and a pulse rate calculation section for calculating pulse rate of the patient based on the pulse wave signal and the signal chosen by the judgment section. 1. An electronic sphygmomanometer for measuring a blood pressure and a pulse rate , comprising:a cuff comprising an air bladder for wrapping around a measurement location of a patient;a pressure sensor mounted on the cuff that measures an inner pressure of the air bladder;an artery volume sensor mounted on the cuff that detects a pulse wave signal of the patient based on a change of volume of an artery;a computation device connected to the pressure sensor and the artery volume sensor that calculates the blood pressure and the pulse rate based on the signal received from the pressure sensor and the artery volume sensor, the computation device comprising:an inner pressure control section that increases and/or decreases the inner pressure of the air bladder at a predetermined timing;a volume sensor signal receive section that receives the pulse wave signal detected by the artery volume sensor;a pressure sensor signal receive section that receives a pressure pulse wave signal, which is superimposed on the inner pressure of the air bladder and detected by the ...

Interface Devices, Systems, and Methods for Use With Intravascular Pressure Monitoring Devices

Embodiments of the present disclosure are configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel. In some particular embodiments, the devices, systems, and methods of the present disclosure are configured to provide FFR measurements in a small, compact device that integrates with existing proximal and distal pressure measurement systems and does not require a separate power source. 1. An interface for intravascular pressure sensing devices , comprising:a distal input configured to receive a distal pressure signal from a distal pressure sensing device;a distal output configured to output the distal pressure signal to a hemodynamic system in a format useable by the hemodynamic system;a proximal input configured to receive a proximal pressure signal from a proximal pressure sensing device;a proximal output configured to output the proximal pressure signal to the hemodynamic system in a format useable by the hemodynamic system;a processor coupled to the distal input, distal output, proximal input, and proximal output, the processor configured to calculate a pressure differential between the distal pressure and the proximal pressure based on the received distal pressure signal and the received proximal pressure signal; anda display in communication with the processor and configured to display the pressure differential calculated by the processor.2. The interface of claim 1 , wherein the distal input claim 1 , distal output claim 1 , proximal input claim 1 , proximal output claim 1 , processor claim 1 , and display are secured to a housing.3. The interface of claim 2 , wherein the housing has a width between 5 cm and 25 cm claim 2 , a height between 5 cm and 25 cm claim 2 , and a depth between 1 cm and 10 cm.4. The interface of claim 3 , wherein the distal pressure sensing device is a pressure-sensing guidewire.5. The interface of claim 4 , wherein the proximal pressure sensing device is a pressure-sensing catheter ...

METHODS AND APPARATUS FOR THE MEASUREMENT OF PULMONARY PARAMETERS

An apparatus includes a mouthpiece to communicate an airflow between a user and an airflow chamber in fluid communication with the mouthpiece; an interrupter in fluid communication with the airflow chamber and adapted to initiate an occlusion event by adjusting between an open state and a closed state, such that fluid communication is at least partially prevented between the airflow chamber and ambient air during the occlusion event initiated by the interrupter; a container in fluid communication with the airflow chamber; a flow rate sensor in fluid communication with the airflow chamber and adapted to measure an airflow exchange between the airflow chamber and the container during the occlusion event; and a controller adapted to determine an instantaneous lung volume based on the measured airflow exchange between the airflow chamber and the container. 1. An apparatus , comprising:a mouthpiece adapted to communicate an airflow between a user and an airflow chamber in fluid communication with the mouthpiece;an interrupter in fluid communication with the airflow chamber and adapted to initiate an occlusion event by adjusting between an open state of the interrupter and a closed state of the interrupter, such that fluid communication is at least partially prevented between the airflow chamber and ambient air during the occlusion event initiated by the interrupter;a container in fluid communication with the airflow chamber;a flow rate sensor in fluid communication with the airflow chamber and adapted to measure an airflow exchange between the airflow chamber and the container during the occlusion event; anda controller adapted to determine an instantaneous lung volume based on the measured airflow exchange between the airflow chamber and the container.2. The apparatus of claim 1 , wherein the controller is adapted to determine an instantaneous lung volume based only on the measured airflow exchange between the airflow chamber claim 1 , container and ambient air.3. The ...

NEURAL MONITORING METHODS AND SYSTEMS FOR TREATING UPPER AIRWAY DISORDERS

Methods and systems for monitoring, preventing and/or treating upper airway disorders such as apnea, dysphagia, reflux and/or snoring are described. The methods and systems monitor the upper airway disorders by processing one or more neural signals obtained from one or more upper airway afferents. Upper airway disorders are prevented and/or treated by delivering one or more stimulations to one or more reflex-related afferents, efferents, muscles, and sensory receptors to manipulate the threshold and/or trigger an upper airway reflex including, but not limited to a swallow reflex and/or a negative-pressure reflex. 1. A method for monitoring a condition in a subject , the method comprising:obtaining one or more neural signals from one or more upper airway afferents of the subject;processing each of the one or more neural signals to obtain at least one neural activity profile, each neural activity profile characterized by at least one of: a neural signal timing, a neural signal amplitude, a neural signal phase, a neural signal position, a neural signal conduction velocity, and any combination thereof;comparing each of the at least one neural activity profiles to one or more activity criteria to associate each neural activity profile with an associated activity type chosen from a respiratory activity type, a deglutition activity type, a vibration activity type, a reflux activity type, and any combination thereof; a respiratory state comprising respiratory timing, respiratory amplitude, respiratory phase, respiratory location, and any combination thereof;', 'a deglutition state comprising solid contact, fluid contact, contact velocity, contact timing, contact amplitude, contact pressure, contact texture, contact temperature, a presence of a unswallowed bolus, and any combination thereof;', 'a vibration state comprising vibration timing, vibration amplitude, vibration phase, vibration location, vibration pattern, and any combination thereof; and', 'a reflux state ...

Estimation of distances and size of lesions in the colon with an imaging capsule

A method of estimating distances in a colon of a subject, including: orally administering to a subject a contrast agent, orally administering an imaging capsule to the subject, emitting radiation from the imaging capsule at a location in the colon, detecting photons that are returned from an interaction of the radiation with an inner wall of the colon and contents of the colon, summating the detected photons with energies corresponding to X-ray florescence interactions to form a first count, summating the detected photons with energies corresponding to Compton back-scattering interactions to form a second count, determining the distance from the imaging capsule to the inner wall of the colon and a concentration of the contrast agent at the location of the imaging capsule in the colon using the values of the first count and the second count.

Heart Age Assessment

An automated method of determining a measure of a subject's heart age comprising the steps of: prompting a user for a plurality of inputs, each relating to an attribute of the subject, each attribute defining one or more of a demographic status of the subject, a lifestyle status of the subject, a physical condition of the subject and a medical history of the subject; receiving, from the user, a plurality of said inputs; determining from said received inputs, a set of parameters for which input data has been received as input from the user; selecting a heart age calculation algorithm from a predetermined set of heart age calculation algorithms according to said set of parameters; and calculating a heart age for the subject according to the selected algorithm; and providing as output said calculated heart age. 122-. (canceled)23. An automated method of estimating blood lipid levels of a subject , said method carried out on a computer system and comprising the automated steps of:a) receiving a plurality of data values, each relating to an attribute of the subject, each attribute defining one or more of a demographic status of the subject, a lifestyle status of the subject, a physical condition of the subject and a medical history of the subject, the data values not including any quantitative measure of a cholesterol level of the subject, said data values either provided by the user through a user input device of the computer system or transferred electronically from another device;b) calculating a CVD risk for the subject based on said data values using a first algorithm stored in a database on the computer system;c) determining one or a range of possible total cholesterol levels and HDL cholesterol levels for the subject consistent with the calculated first CVD risk by comparison of the first CVD risk with statistical average CVD risk as a function of measured total and HDL cholesterol levels in a population;d) determining a statistical average total cholesterol level ...

PULSE WAVE MEASUREMENT APPARATUS AND PROGRAM

A pulse wave measurement apparatus includes a light emitting device that applies light to a measurement position at which a pulse wave is measured, and a plurality of light receiving devices that output measurement signals based on the amount of received light which is applied from the light emitting device and is reflected from the measurement position. The control unit of the pulse wave measurement apparatus performs the independent component analysis on the measurement signals output from the plurality of light receiving devices, and calculates the weighting factors of each component when each of the measurement signals is divided into a plurality of components. The control unit calculates the dispersion of the calculated weighting factors for each component, and specifies a component in which the calculated dispersion is the smallest. The control unit generates pulse wave information indicative of the pulse wave based on the specified component. 1. A pulse wave measurement apparatus comprising:a plurality of light receiving units that output measurement signals each indicative of a received amount of light which is irradiated to a measurement position where pulse waves are measured and passes through or is reflected from the measurement position;an independent component analysis unit that performs an independent component analysis on the measurement signals which are output from the plurality of light receiving units, divides each of the measurement signals into a plurality of components, and calculates weighting factors of each of the plurality of components;a dispersion calculation unit that calculates a value indicative of a degree of dispersion of values of the weighting factors which are calculated by the independent component analysis unit for each of the plurality of components;a component specification unit that specifies a component of the plurality of components whose value indicative of the degree of dispersion calculated by the dispersion calculation ...

RESPIRATION INDUCING APPARATUS AND CONTROL METHOD THEREOF

A respiration inducing apparatus is provided, and includes a respiration waveform data collection unit for collecting respiration waveform data from a user; a storage unit for storing a respiration waveform template; a controller for comparing the respiration waveform data and the respiration waveform template and determining a respiration fidelity based on a similarity of a comparison result; and a user interface unit for displaying at least one of the respiration waveform data, the respiration waveform template, and the respiration fidelity. 1. A respiration inducing apparatus , comprising:a respiration waveform data collection unit for collecting respiration waveform data from a user;a storage unit for storing a respiration waveform template;a controller for comparing the respiration waveform data and the respiration waveform template and determining a respiration fidelity based on a similarity of a comparison result; anda user interface unit for displaying at least one of the respiration waveform data, the respiration waveform template, and the respiration fidelity.2. The respiration inducing apparatus of claim 1 , wherein the respiration waveform data collection unit comprises an acceleration sensor for sensing an acceleration applied to the respiration inducing apparatus.3. The respiration inducing apparatus of claim 2 , wherein the controller interprets the respiration waveform data based on acceleration information from the respiration waveform data collection unit.4. The respiration inducing apparatus of claim 1 , wherein the controller determines the respiration fidelity based on a correlation between the respiration waveform data and the respiration waveform template.6. The respiration inducing apparatus of claim 1 , wherein the respiration fidelity is represented as a score through playing of a preset game claim 1 , and the controller renders the preset game and controls the user interface unit to display a rendered game screen.7. The respiration ...

ENERGY AWARE SENSOR MANAGEMENT FOR WEARABLE MEDICAL SYSTEMS OPTIMIZATION

In some aspects, the invention provides compositions and methods for inhibiting viral infection. In some aspects, the invention provides compositions and methods useful for identifying antiviral compounds. 1. A method of inhibiting viral infection of a cell comprising contacting the cell with a PLA2G16 inhibitor.2. The method of claim 1 , wherein the virus is a Picornavirus.3. The method of claim 2 , wherein the Picornavirus is an enterovirus.4. The method of claim 2 , wherein the Picornavirus is a coxsackievirus.5. The method of claim 2 , wherein the Picornavirus is a hepatovirus.6. The method of claim 2 , wherein the Picornavirus is a rhinovirus.7. The method of claim 1 , wherein the cell is a vertebrate cell.8. The method of claim 1 , wherein the cell is a mammalian cell.9. The method of claim 1 , wherein the cell is a human cell.10. The method of claim 1 , wherein the inhibitor inhibits expression of PLA2G16.11. The method of claim 1 , wherein the inhibitor inhibits enzymatic activity of PLA2G16.12. A method of treating a viral infection in a subject claim 1 , the method comprising administering a PLA2G16 inhibitor to a subject in need of treatment for a viral infection.13. The method of claim 12 , wherein the viral infection is a Picornavirus infection.14. The method of claim 13 , wherein the Picornavirus is an enterovirus.15. The method of claim 13 , wherein the Picornavirus is a coxsackievirus.16. The method of claim 13 , wherein the Picornavirus is a hepatovirus.17. The method of claim 13 , wherein the Picornavirus is a rhinovirus.18. The method of claim 12 , wherein the subject is a vertebrate.19. The method of claim 12 , wherein the subject is a mammal.20. The method of claim 12 , wherein the subject is human.21. The method of claim 12 , wherein the inhibitor inhibits expression of PLA2G16.22. The method of claim 12 , wherein the inhibitor inhibits enzymatic activity of PLA2G16.23. A method of identifying a candidate antiviral compound comprising steps of: ...

ENDOSCOPE SYSTEM, PROCESSOR DEVICE THEREOF, AND IMAGE PRODUCING METHOD

First and second white light is generated by excitations of phosphors with first and second laser beams having center wavelengths of 473 nm and 445 nm, respectively. The first and second white light is applied, in respective frames, sequentially to a region of interest in a subject. A color image sensor images the region of interest in the each frame. Based on a shift amount, calculated from green signals of first and second frames, between images, an image of a blue signal of the first frame is moved to be aligned with an image of a green signal and an image of a red signal of the second frame. After the alignment, an oxygen saturation image representing an oxygen saturation level of hemoglobin in blood is produced from the blue signal of the first frame and green and red signals of the second frame, and displayed on a display. 1. An endoscope system comprising:a lighting section for applying at least first illumination light and second illumination, light, in respective frames, to a region of interest, a wavelength range of the first illumination light being different from a wavelength range of the second illumination light, the region of interest including a blood vessel;an image signal acquisition section having a color image sensor with an array of pixels of at least three primary colors, the image signal acquisition section imaging the region of interest in the each frame, the image signal acquisition section imaging the region of interest illuminated with the first illumination light to acquire three color signals of a first frame, the image signal acquisition section imaging the region of interest illuminated with the second illumination light to acquire three color signals of a second frame;a shift amount calculator for calculating a shift amount between an image of the first frame and an image of the second frame based on the color signals of same color;a registration section for aligning images of predetermined color signals, used for calculating an ...

Estimation of insulin sensitivity from cgm and subcutaneous insulin delivery in type 1 diabetes

In a method of determining insulin sensitivity in a patient, glucose level is sensed continuously. A first area under the curve representing the glucose level over time is calculated. An amount of insulin that has been administered to the patient is sensed. An estimation of insulin on board the patient is calculated based on the glucose level and the amount of insulin administered to the patient. A second area under the curve representing the insulin on board over time is calculated. Patient data indicative of at least one patient physical parameter is received. Information indicative of amount of glucose ingested by the patient during a meal is received. An insulin sensitivity output indicative of ability of insulin to stimulate glucose utilization and inhibit glucose production in the patient based on the first and second area under the curve, the patient data and the meal information is generated.

METHOD FOR MYOCARDIAL SEGMENT WORK ANALYSIS

The invention relates to medical monitoring apparatuses, methods, and computer programs for determining power or work as a function of time for individual myocardial segments based on strain and pressure measurements. Compared to prior art determinations of determination of mechanical power or work for individual segments, the invention is advantageous as it provides such determination solely from a pressure measurement or estimate and a measurement of strain, preferably by echocardiography, such as speckle tracking ultrasound imaging. This allows a fast, easy and non-invasive determination with high temporal and spatial resolution. A number of indices for segment work can be calculated which can be used as markers for the individual segment function as well as for a selection of patient for CRT. 1. An apparatus for receiving preparing and presenting data related to individual myocardial segment work from tissue strain imaging data , the apparatus comprising:a medical imaging device for non-invasively recording tissue strain imaging data for two or more myocardial segments; and 'calculating mechanical power, P(t), and/or mechanical work, W(t), traces for two or more individual myocardial segments as a function of time for a period comprising the time interval from the beginning of isovolumetric contraction and until the end of isovolumetric relaxation from ventricular tissue strain traces for each of the two or more myocardial segments, and a non-invasively determined pressure trace proportional to a ventricular pressure and in temporal synchrony with the strain traces.', 'an electronic processor capable of215-. (canceled)17. The apparatus according to claim 16 , wherein the mechanical work for segment n claim 16 , W(t) claim 16 , is calculated as:{'br': None, 'i': W', 't', 'P', 't', 'dt′+C, 'sub': n', '0', 'n', '2n, 'sup': 't', '()=∫(′)'}{'sub': '2n', 'wherein t′ is an integration variable and Cis a constant for segment n.'}18. The apparatus according to claim 1 , ...

BLOOD PRESSURE INFORMATION MEASUREMENT DEVICE AND BLOOD PRESSURE INFORMATION MEASUREMENT METHOD

A CPU acquires factor information for a degree of arteriosclerosis, stores a plurality of pseudo blood flow waveforms, generates a waveform estimated as a blood flow waveform by compositing the plurality of pseudo blood flow waveforms based on the factor information, decomposes a pulse waveform into waveforms of an ejected wave and a reflected wave using the pulse waveform and the waveform estimated as the blood flow waveform, and calculates an index of the degree of arteriosclerosis from a relationship between the ejected wave and the reflected wave obtained by decomposing the pulse waveform. 1. A blood pressure information measurement device for calculating an index of a degree of arteriosclerosis of a measurement subject as blood pressure information , comprising:a detection member comprising a plurality of pressure sensors; anda central processing unit that detects a pulse waveform by bringing the detection member into contact with an exterior of a measurement site of the measurement subject, acquires factor information for the degree of arteriosclerosis;', 'stores a plurality of pseudo blood flow waveforms;', 'generates a waveform estimated as a blood flow waveform by compositing the plurality of pseudo blood flow waveforms based on the factor information;', 'decomposes the pulse waveform into waveforms of an ejected wave and a reflected wave using the pulse waveform and the waveform estimated as the blood flow waveform; and', 'calculates the index of the degree of arteriosclerosis from a relationship between the ejected wave and the reflected wave obtained by decomposing the pulse waveform., 'wherein the central processing unit;'}2. The blood pressure information measurement device according to claim 1 , wherein the factor information is at least one from the group consisting of: an augmentation index (AI) value claim 1 , a difference between times of appearances of the ejected wave and the reflected wave claim 1 , and a difference between times of peaks of ...

Method and a device for determining the hydration and/or nutrition status of a patient

The invention relates to the field of monitoring the hydration and/or nutrition status of a patient. According to the invention a method is provided to determine at least one of a mal-hydration component, an adipose tissue component and a lean tissue component of a patient comprising the steps of determining chemical or physical properties of the patient and deriving the at least one component on the basis of the determined chemical or physical properties of the patient and previously determined values of a mass or volume fraction of water in lean tissue and a mass or volume fraction of water in adipose tissue. The invention also relates to a device for carrying out the method according to the invention and to a computer program product to be used on such a device. 1. A method to determine at least one of a mal-hydration component , an adipose tissue component and a lean tissue component of a patient comprising the steps of:determining chemical or physical properties of the patient andderiving the at least one component on the basis of the determined chemical or physical properties and previously determined values of a mass or volume fraction of water in lean tissue and a mass or volume fraction of water in adipose tissue.2. The method according to characterised in that the at least one component is the mass of that component of the patient.3. The method according to characterised in that the at least one component is the volume of that component of the patient.4. The method according to characterised in that the chemical or physical properties of the patient comprise at least one of the whole body mass claim 1 , the lipid mass and the total bone mineral content mass of the patient.5. The method according to characterised in that the chemical or physical properties of the patient comprise the volume or mass of at least one of the total water claim 1 , the extracellular water and the intracellular water of the patient.6. The method according to characterised in that ...

APPARATUS METHOD AND SYSTEM FOR MEASURING STRAIN IN BIOLOGICAL TISSUE

An apparatus for in-situ sensing of longitudinal and transverse strain in biological tissue (e.g. tendons and ligaments) includes a set of sensing electrodes that contact biological tissue and enable measurement of an electrical property of the biological tissue along two or more directions. The apparatus may also include a sensing module that senses the electrical property of the biological tissue along the two or more directions to provide multi-directional measurements that are captured by a logging module. The apparatus may also include a transmission module that transmits the captured measurements to a data analysis workstation or the like. The data analysis workstation may include a strain estimation module that receives the multi-directional measurement and estimates a longitudinal strain and a transverse strain therefrom. A corresponding system and method for in-situ sensing of longitudinal and transverse strain in biological tissue is also presented. 1. An apparatus for in-situ sensing of longitudinal and transverse strain in biological tissue , the apparatus comprising:a plurality of sensing electrodes configured to contact biological tissue and enable measurement of an electrical property of the biological tissue along two or more directions;a sensing module configured to sense the electrical property of the biological tissue along the two or more directions to provide a multi-directional measurement of the electrical property;a logging module configured to capture one or more multi-directional measurements to provide captured measurements; andwherein the logging module comprises a data port for reading the captured measurements.2. The apparatus of claim 1 , wherein the electrical property is selected from the group consisting of electrical resistance claim 1 , electrical potential and electrical current.3. The apparatus of claim 2 , wherein the plurality of sensing electrodes are arranged to enable measurement of the electrical property along at least 3 ...

METHOD AND APPARATUS FOR DETERMINING AN AUTOFLUORESCENCE VALUE OF SKIN TISSUE

A method for determining an autofluorescence value of skin tissue of a subject, comprising the steps of: 1. A method for determining an autofluorescence value of skin tissue of a subject , comprising the steps of:irradiating material of said skin tissue with electromagnetic excitation radiation of at least one wavelength and/or in at least one range of wavelengths;measuring an amount of electromagnetic, fluorescent radiation emitted by said material in response to said irradiation; andgenerating, based upon said measured amount of fluorescent radiation, a measured autofluorescence value for the concerning subject;wherein the determined autofluorescence value is obtained by correcting the measured autofluorescence value for characteristics of a reflected part of an excitation spectrum and/or an emission spectrum from said material in response to such irradiation and/or for characteristics of reflectance measurements at wavelengths other than said at least one wavelength and/or other than in said at least one range of wavelengths, in such manner that the dependency of the determined autofluorescence value upon different UV-skin tissue reflectances, that different respective subjects may have, is minimized or at least diminished.2. A method according to claim 1 , wherein the determined autofluorescence value is obtained by correcting the measured autofluorescence in accordance with a relationship between a first measured intensity or reflectance at a first wavelength or wavelength range and a second measured intensity or reflectance measured at a second wavelength or wavelength range different from said first wavelength or wavelength range.3. A method according to claim 2 , wherein the first and the second wavelengths or wavelength ranges are within a range of wavelengths with which the skin tissue is irradiated for excitation.4. A method according to claim 2 , wherein the first wavelength or wavelength range is in a range of 360-365 nm and wherein the second ...

MAGNETIC RESONANCE ELASTOGRAPHY FOR ULTRASOUND IMAGE SIMULATION

Ultrasound data is simulated using magnetic resonance (MR) elastography. MR elastography provides tissue characteristic information, such as elastic modulus, velocity, or stiffness. This tissue characteristic information indicates a density or viscosity of the tissue, allowing simulation of ultrasound data with MR acquired data. The same MR imaging system may be used to acquire the MR elastography and pre-operative anatomy information. The actual ultrasound information may be registered with simulated ultrasound information for registration of the actual ultrasound information with the MR anatomy information. 1. A method for ultrasound data simulation using magnetic resonance elastography , the method comprising:{'b': '30', 'obtaining (), with a magnetic resonance (MR) imaging system, MR anatomy data representing anatomy of a patient;'}{'b': '32', 'obtaining (), with the MR imaging system, MR elastography data representing an elastic characteristic of the anatomy of the patient;'}{'b': 36', '26, 'deriving (), with a processor (), information related to density from the MR elastography data;'}{'b': '44', 'simulating () model ultrasound data from the information related to density; and'}{'b': '46', 'registering () actual ultrasound data with the MR anatomy data as a function of the model ultrasound data.'}230. The method of further comprising obtaining () T1W or T2W data.332. The method of wherein obtaining () MR elastography data comprises measuring claim 1 , with the MR imaging system claim 1 , a propagation of a mechanical wave induced in the patient.432. The method of wherein obtaining () the MR elastography data comprises generating an oscillating field gradient in synchronization with acoustic mechanical waves claim 1 , measuring a phase shift with the MR imaging system claim 1 , and estimating an amplitude of displacement as a function of the phase shift.536. The method of wherein deriving () the information related to density comprises determining density ...

METHOD AND APPARATUS FOR ESTIMATING A PULSE ARRIVAL TIME VALUE

Method and apparatus for estimating an arrival time (PAT) value of a subject in an automatic and unsupervised fashion from a sequence of electrical impedance tomography (EIT) images. The method comprises: providing an EIT imaging device adapted to record impedance signal distribution within a measurement region of the subject; measuring a sequence of temporally discrete EIT images during a predetermined measuring time period in the measurement region using the EIT imaging device, each EIT image comprising one or a plurality of EIT pixel subsets, each of said one or a plurality of EIT pixel subset representing an impedance value; generating one or a plurality of time series, each of said one or a plurality of time series representing a variation of the impedance value of the sequence of EIT images; and estimating the PAT value from each of said one or a plurality of time series. 1. Method for estimating an arrival time value of arterial pressure pulses (PAT value) of a subject from a sequence of electrical impedance tomography (PIT) images , comprising:providing an EIT imaging device adapted to record impedance signal distribution (EIT image) within a measurement region of the subject;measuring a sequence of temporally discrete EIT images during a predetermined measuring time period in the measurement region using the EIT imaging device, each EIT image comprising one or a plurality of EIT pixel subsets, each of said one or a plurality of EIT pixel subset representing an impedance value;generating one or a plurality of time series, each of said one or a plurality of time series representing a variation of the impedance value of the sequence of one or plurality of EIT pixel subsets; andestimating the PAT value from each of said one or a plurality of time series.2. Method according to claim 1 , further comprising: generating a time-based PAT image representative of the sequence of EIT images claim 1 , said time-based PAT image comprising one or a plurality of PAT pixel ...

System and method for storing and providing patient-related data

According to various embodiments, a regional oximetry sensor may include a light emitting element configured to emit light, a light detector configured to receive the light, and a memory device configured to store a baseline. The baseline stored by the memory device enables a regional oximetry monitor to display the baseline on a display of the regional oximetry monitor.

SYSTEM AND METHOD FOR CONVERTING AN INPUT SIGNAL INTO AN OUTPUT SIGNAL

The present invention relates to a system and a method for processing data obtained from an input signal () comprising physiological information () representative of at least one at least partially periodic vital signal (). The physiological information () is derivable from visible radiation () reflected by an object (). The system comprises a detector means () for detecting at least one vital signature () in the input signal () and a converter means () for creating an output signal () by modifying the input signal () depending on the detected vital signature (). The output signal () comprises an artificial signature () at least partially replacing a respective vital signature () of the at least one vital signature () of the input signal (). In one embodiment the system further comprises a sensor means () for detecting visible electromagnetic radiation () within at least one particular wavelength range. 124. Privacy preservation system for processing data obtained from an input signal () comprising physiological information derived from visible radiation reflected by an object , the physiological information being representative of at least one at least partially periodic vital signal , the system comprising:a detector means for detecting at least one vital signature in the input signal, wherein the input signal comprises a continuous or discrete sequence of image frames related to a specific signal space, the at least one vital signature varying over time and corresponding to the at least one at least partially periodic vital signal, wherein the at least one at least partially periodic vital signal is selected from the group consisting of heart rate, respiration rate, and heart rate variability, and wherein the at least one at least partially periodic vital signal is obtained from slight variations of skin tone color over time,a converter means for creating an output signal by modifying the input signal depending on the detected vital signature,wherein the output ...

BLOOD PRESSURE MEASUREMENT APPARATUS AND BLOOD PRESSURE MEASUREMENT METHOD

A blood pressure measurement apparatus includes a blood pressure measurement unit, a bio-information acquisition unit, a depth calculation unit, a storage unit and a decision unit. The bio-information acquisition unit continuously acquires bio-information of a subject. The depth calculation unit repeatedly calculates depth indices each indicating a sleep stage of the subject on the basis of the acquired bio-information. The storage unit stores the calculated depth indices. The decision unit decides whether the sleep stage of the subject in sleep satisfies a starting condition, on the basis of a first depth index stored in the storage unit and a second depth index calculated by the depth calculation unit. The blood pressure measurement unit measures blood pressure data of the subject when the sleep stage is decided to satisfy the starting condition. 1. A blood pressure measurement apparatus , comprising:a blood pressure measurement unit that measures blood pressure of a subject;a bio-information acquisition unit that continuously acquires bio-information of the subject;a depth calculation unit that repeatedly calculates a depth index indicating a sleep stage of the subject on the basis of the acquired bio-information;a storage unit in which the calculated depth index is stored; anda decision unit that decides whether the sleep stage of the subject in sleep satisfies a predetermined condition, on the basis of a first depth index stored in the storage unit and a second depth index calculated by the depth calculation unit,wherein the blood pressure measurement unit measures the blood pressure when the decision unit decides that the sleep stage satisfies the condition.2. The blood pressure measurement apparatus according to claim 1 ,wherein the first depth index is the depth index indicating a deepest sleep stage among a plurality of depth indices each calculated on the basis of the bio-information acquired at a different time point.3. The blood pressure measurement ...

METHOD AND APPARATUS FOR DETECTING CARDIAC SIGNALS

Devices and systems provide methods for detecting cardiac signals from head or facial biopotential sensors. In one embodiment, a facial biopotential signal is measured by a set of sensors. A processor derives a cardiac signal from the facial biopotential signal. Optionally, heart rate is detected from the cardiac signal. Heart rate variability may be determined and evaluated by the processor to generate warnings or messages from the evaluation. One or more head or facial biopotential electrodes for measuring the facial biopotential signal may be integrated in or at a contact surface of head support structures such as a headgear support or respiratory treatment mask. In some such embodiments a controller of a respiratory treatment apparatus may serve as a cardiac signal detector by processing the facial biopotential signal from the sensors and may make control adjustments or generate warnings based on an evaluation of detected signals. 1. A method for detecting a cardiac signal comprising:measuring a facial biopotential signal from a set of electrodes connected to a patient; anddetecting by a processor a cardiac signal from the facial biopotential signal.2. The method of wherein the measuring comprises determining a voltage difference between signals of at least two electrodes of the set of electrodes.32. The method of any one of - wherein the measuring comprises determining field strength with the set of electrodes claims 1 , the set of electrodes comprising a non-contact sensor.43. The method of any one of - wherein the measuring comprises measuring current between two electrodes of the set of electrodes.54. The method of any one of - wherein the detecting comprises signal processing of the facial biopotential signal.6. The method of wherein the processing comprises filtering the facial biopotential signal.76. The method of any one of - further comprising determining a heart rate from the cardiac signal.8. The method of wherein the determining the heart rate ...

METHOD OF PROCESSING THORACIC REFLECTED RADIO INTERROGATION SIGNALS

A method of evaluating or monitoring the medical state of a human subject on the subject includes the steps of: positioning an antenna side of a self-contained radio apparatus for non-invasive, thoracic radio interrogation of a human subject proximally to the heart of the human subject; providing a radio frequency interrogation interference signal from the human subject, the radio frequency interrogation interference signal being low frequency components of reflections of a radio interrogation signal transmitted into the thorax of the subject; and determining with the apparatus on the subject at least at least one stroke volume value of the subject from radio frequency interrogation interference signal generated by the apparatus. 1. A method of electronically evaluating medical state of a human subject in near real time on the subject comprising the steps of:positioning an antenna side of a self-contained radio apparatus for non-invasive, thoracic radio interrogation of a human subject proximally to the heart of the human subject outside the human subject, the apparatus including a radio transmitter operably connected to the antenna and configured to transmit only an unmodulated radio frequency interrogation signal of a predetermined, fixed frequency through the antenna and into the proximally positioned human subject; a radio receiver operably connected to the antenna and configured to capture through the antenna reflections of the radio frequency interrogation signal returned from the human subject; processing circuitry including an electronic processor coupled with the radio receiver and a battery power source powering the apparatus;providing a radio frequency interrogation interference signal from the human subject and the radio receiver to the processing circuitry of the apparatus, the radio frequency interrogation interference signal being low frequency components of reflections of a radio interrogation signal transmitted into the thorax of the human subject ...

SYSTEM AND METHOD TO EVALUATE CARDIOVASCULAR HEALTH

Systems and methods are described herein to evaluate a candidate medication as it relates to a subject's cardiovascular health. A processing component is employed to measure a first value of one or more cardiovascular markers, via a computer, which are associated with a circulatory system of each subject that is to receive the candidate medication. The candidate medication is administered to each subject and a second value of one or more cardiovascular markers are measured subsequent to the administration as of the candidate medication. Continued testing of the candidate medication can be continued dependent upon the change in the one or more cardiovascular markers. 1. A method , comprising:a processing component employed to calculate a first stroke volume of a subject;administering a medication to the subject;calculating a second stroke volume of the subject; andevaluating the disparity between the first stroke volume and the second stroke volume to determine whether to continue administration of the medication,wherein if the second stroke volume is less than or equal to the first stroke volume, administration of the medication is continued and if the second stroke volume is greater than the first stroke volume, administration of the medication is discontinued.2. The method according to claim 1 , wherein the medication is related to modification of the cardiovascular system of the subject.3. The method according to claim 2 , wherein the cardiovascular medication is related to hypertension.4. The method according to claim 1 , wherein the first and second stroke volumes are calculated based upon the same cardiovascular markers.5. The method according to claim 1 , wherein the first and second stroke volumes are calculated based upon a cardiac output and a heart rate of the subject claim 1 , wherein the first and second stroke volumes are each equal to the cardiac output divided by the heart rate.6. The method according to claim 1 , wherein the first and second stroke ...

MINIMALLY INVASIVE DETERMINATION OF COLLATERAL VENTILATION IN LUNGS

Minimally invasive methods, systems and devices are provided for qualitatively and quantitatively assessing collateral ventilation in the lungs. In particular, collateral ventilation of a target compartment within a lung of a patient is assessed by advancement of a catheter through the tracheobronchial tree to a feeding bronchus of the target compartment. The feeding bronchus is occluded by the catheter and a variety of measurements are taken with the use of the catheter in a manner which is of low risk to the patient. Examples of such measurements include but are not limited to flow rate, volume and pressure. These measurements are used to determine the presence of collateral ventilation and to quantify such collateral ventilation. 1. A method for determining the function or malfunction of an endobronchial prosthesis positioned within a lung passageway of a patient , said method comprising:occluding the lung passageway proximally of the endobronchial prosthesis;allowing the patient to breathe air without any markers; andmeasuring air flow or accumulation from the lung passageway over time wherein said measurement is correlative to the function or malfunction of the endobronchial prosthesis.2. A system for detecting collateral ventilation into a lung compartment in a patient , said system comprising:a catheter adapted to be introduced transtracheally to a bronchus leading to a target lung compartment;an occlusion member on a distal region of the catheter, said occlusion member being adapted to selectively occlude the bronchus; anda flow measurement sensor on the catheter to detect flow of air from the isolated compartment as the patient exhales.3. A system for detecting collateral ventilation into a lung compartment in a patient , said system comprising:a catheter adapted to be introduced transtracheally to a bronchus leading to a target lung compartment;an occlusion member or a distal region of the catheter, said occlusion member being adapted to selectively ...

APPARATUS FOR DETECTING A STRENGTH OF LIPS-CLOSING AND METHOD THEREOF

An apparatus for detecting a strength of lips-closing is applied for training and evaluation during treatment of temporomandibular disorders (TMD), according to the strength of the lips-closing of the user, the clinical staff and the patients are able to evaluate the severity of lips-closing impairment. It can also be used as training tool with which the effect can be monitored before, during, and after rehabilitation courses. The apparatus includes an air bag, a pressure sensing unit and a micro-controller module. The user puts the air bag, which is able to be pumped air in or out, between the lips. The pressure sensing unit is connected to the air bag for detecting a pressure formed by the lips of the user forcing the air bag, to generate a signal. The micro-controller module is electrically connected to the pressure sensing unit for converting the signal into the strength of lips-closing. 1. An apparatus for detecting a strength of lips-closing comprising:an air bag placed between the lips of an user, wherein the air bag can be inflated or deflated to change the pressure therein;a pressure sensing unit connected to the air bag to detect a pressure exerted on the air bag by the user closing the lips, so as to produce a signal; anda micro-controller module, electrical connected to the pressure sensing unit, for converting the signal into the strength of lips-closing.2. The apparatus for detecting a strength of lips-closing of claim 1 , further comprising a pump and a deflating valve claim 1 , wherein the pump and the deflating valve are electrically connected to the micro-controller module claim 1 , and the micro-controller module controls the pump to inflate the air bag or controls the deflating valve to deflate the air bag.3. The apparatus for detecting a strength of lips-closing of claim 2 , further comprising an user interface electrically connected to the micro-controller module for the user to operate the micro-controller module claim 2 , thereby control the ...

Non-invasive portable dehydration diagnostic system, device and method

A non-invasive patient hydration monitoring system, device, and method are disclosed. The invented device utilizes a non-invasive photo-plethysmographic (PPG) finger- or toe-probe with an infrared transceiver to measure blood perfusion or circulation in an extremity. Such perfusion data is processed using correlation techniques into patient hydration data by a microprocessor and software application that preferably resides in a cell phone or similar portable hardware/firmware/software platform. Individual and successive patients can be quickly screened, baselined, diagnosed, and reported to identify individuals with dehydration conditions that are indicators of more important health issues such as disease and contagion. 1. A non-invasive human-patient fluid volume monitor comprising:a non-invasive electro-optical detector configured to monitor a human patient's pulsatile blood flow, the detector including an infrared (IR) light to detect blood flow changes in an extremity of the patient;a digital computing element including a digital processor and a memory for storing and instructions and data, the digital computing element being configured to be operatively coupled with the detector to monitor the patient's pulsatile blood flow and to calculate a fluid volume measurement therefrom; anda display coupled with the digital computing element, the display configured to present human-patient fluid volume data thereon in human-readable report format.2. The monitor of claim 1 , wherein the digital computing element includes a first algorithm structure configured to produce a data stream representing the patient's pulsatile blood flow in the form of a circulation index (CI) claim 1 , and wherein the digital computing element further includes a second algorithm structure configured to produce from the CI a data stream representing the patient's fluid volume in the form of a hydration index (HI).3. The monitor of claim 2 , wherein the electro-optical detector is coupled to the ...

SYSTEMS AND METHODS FOR ESTIMATING BODY COMPOSITION

In one embodiment, a system and method for estimating body composition relate to constructing a three-dimensional model of a subject based upon captured images of the subject, estimating the body volume of the subject using the three-dimensional model, and estimating the body composition of the subject based in part upon the estimated volume. 1. A method for estimating body composition of a subject , the method comprising:capturing images of the subject;constructing a three-dimensional model of the subject based upon the images;estimating the body volume of the subject using the three-dimensional model; andestimating the body composition of the subject based in part upon the estimated volume.2. The method of claim 1 , wherein capturing images comprises capturing digital images of the subject.3. The method of claim 1 , wherein capturing images comprises capturing a profile image and at least one of a front image or a back image of the subject.4. The method of claim 1 , wherein estimating the body volume of the subject comprises dividing the three-dimensional model into discrete elliptical segments claim 1 , calculating the volume of each elliptical segment claim 1 , and summing the volumes of all elliptical segments to obtain a total volume.5. The method of claim 1 , wherein estimating the body volume of the subject comprises dividing the three-dimensional model into discrete segments whose shape is based upon the contours of an actual cross-dissection of a human body claim 1 , calculating the volume of each segment claim 1 , and summing the volumes of all segments to obtain a total volume.6. The method of claim 1 , wherein estimating body composition of the subject comprises estimating body density of the subject from the estimated body volume and the mass of the subject.7. The method of claim 6 , wherein estimating body composition of the subject further comprises calculating the subject's body fat percentage using a relation that directly relates body fat ...

SYSTEM AND METHOD OF IDENTIFYING BREATHS BASED SOLELY ON CAPNOGRAPHIC INFORMATION

Breaths of a subject are identified based on the concentration of carbon dioxide at or near the airway of the subject. Troughs corresponding to inhalation are identified and plateaus corresponding to exhalation are identified. A breath is identified responsive to a trough being followed by a plateau. 1. A system configured to detect breaths based on capnographic information , the system comprising:a sensor configured to generate output signals over time conveying information related to a concentration of carbon dioxide in gas at or near the airway of a subject; a concentration module configured to determine a level of the concentration of carbon dioxide in the gas at or near the airway of the subject over time based on the output signals;', 'a trough identification module configured to identify troughs in the level of the concentration of carbon dioxide, via satisfaction per trough of a trough concentration threshold and a trough duration threshold over time, corresponding to inhalations by the subject, wherein the trough identification module is further configured to identify a potential trough via a comparison of a level of carbon dioxide at a beginning of the potential trough with a level of carbon dioxide at an end of the potential trough, wherein responsive to a difference between (i) the level at the beginning of the potential trough and (ii) the level of carbon dioxide at the end of the potential trough being less than a trough differential threshold, the trough identification module identifies the potential trough as a trough corresponding to an inhalation;', 'a plateau identification module configured to identify plateaus in the level of the concentration of carbon dioxide over time corresponding to exhalations by the subject; and', 'a breath identification module configured to identify breaths based on identification of troughs and plateaus over time by the trough identification module and the plateau identification module, respectively, wherein responsive ...

SYSTEM AND METHOD FOR CHARACTERIZING CIRCULATORY BLOOD FLOW

A computer-implemented method for characterizing circulatory blood volume and autoregulatory compensatory mechanisms to maintain circulatory blood volume is disclosed. A biological signal that emulates the arterial pulse wave is collected from a sensor. Three derived parameters are extrapolated from the biological signal. The first parameter, circulatory stress, reflects of the changes of the heart rate frequency. The second, circulatory blood volume, reflects the changes in the frequency strength of the heart rate frequency. The third, Pulse Volume Alteration (PVA) Index is a ratio of the sum of the strengths of the heart rate frequency harmonics to the strength of the heart rate frequency of the unprocessed biological signal. Each parameter is compared to a threshold value and assessed to determine an adequacy of circulatory blood volume and an appropriateness of the autoregulatory mechanisms used to maintain circulatory blood volume adequacy. 1. A computer-implemented method , comprising the steps of:a. acquiring, using a processor, a biological signal from a sensor;b. conditioning, using said processor, said signal to create a conditioned signal;c. processing, using said processor, said conditioned signal; andd. calculating, using said processor, a derived parameter, wherein calculating comprises calculating a PVA Index.2. The method as in claim 1 , further comprising the step of comparing claim 1 , using said processor claim 1 , said derived parameter to a threshold value.3. The method as in claim 1 , wherein said biological signal is a photo-optic signal.4. The method as in claim 1 , wherein said sensor is a photo-optic device.5. The method as in claim 1 , wherein calculating a derived parameter further comprises calculating one of circulatory blood volume and circulatory stress.6. The method as in claim 1 , wherein said step of conditioning comprises at least one of the following the steps of:a. amplifying, using said processor, said biological signal;b. ...

NEBULIZER WITH INTRA-ORAL VIBRATING MESH

A nebulizer includes a main body that has a nebulizer outlet and an air channel in communication with the nebulizer outlet. The main body supports a medicine reservoir and a mesh that engages the medicine reservoir and air channel and vibrates to atomize medicine from the medicine reservoir into the air channel for discharge through the nebulizer outlet. The nebulizer outlet and mesh are configured to be received within the oral cavity of the patient when the nebulizer is in use. 1. A nebulizer comprising: a nebulizer outlet;', 'an air channel in communication with the nebulizer outlet;', 'a medicine reservoir; and', 'a mesh that engages the medicine reservoir and air channel and vibrates to atomize medicine from the medicine reservoir into the air channel for discharge through the nebulizer outlet;, 'a main body comprising,'}wherein said nebulizer outlet and mesh are configured to be received within the oral cavity of the patient when the nebulizer is in use.2. The nebulizer according to wherein said mesh comprises a mesh plate having multiple apertures through which medicine passes from the medicine reservoir to be atomized into the air channel.3. The nebulizer according to wherein said apertures are tapered and each aperture has a larger cross-section on the medicine reservoir side and a smaller cross-section at the air channel.4. The nebulizer according to wherein said apertures are dimensioned at the air channel to form atomized droplets of a specific size range.5. The nebulizer according to comprising an actuator connected to the mesh plate to vibrate the mesh plate.6. The nebulizer according to comprising at least one medicine receiver configured to receive medicine claim 1 , and a medicine feed line connecting the medicine receiver to the medicine reservoir to supply medicine to the medicine reservoir.7. The nebulizer according to wherein the at least one medicine receiver comprises a puncture tube for piercing a medicine container received within the ...