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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 6780. Отображено 100.
26-01-2012 дата публикации

Method for fusing a human or animal joint as well as fusion device and tool set for carrying out the method

Номер: US20120022535A1
Автор: Andrea Mueller, Elmar Mock, Jorg Mayer, Mario Lehmann, Milica Berra, Stephanie Mehl, Urs Weber
Принадлежит: WW Tech AG

The fusion device for fusing a synovial joint of a human or animal patient, in particular a human facet joint, finger joint or toe joint, includes two pin-shaped anchorage portions ( 1 ) and arranged therebetween a stabilization portion ( 2 ). The anchorage portions ( 1 ) include a thermoplastic material which is liquefiable by mechanical vibration. The stabilization portion ( 2 ) preferably has a surface which is equipped for enhancing osseointegration. The anchorage portions ( 1 ) have a greater thickness (T 1 ) and a greater depth (D) than the stabilization portion ( 2 ). Then the fusion device is pushed between the articular surfaces and mechanical vibration, in particular ultrasonic vibration, is applied to the proximal face ( 4 ) of the fusion device. Thereby the liquefiable material is liquefied where in contact with the bone tissue and penetrates into the bone tissue, where after re-solidification it constitutes a positive fit connection between the fusion device and the bone tissue.

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Номер записи: 1
02-02-2012 дата публикации

Osteoarthritis treatment and device

Номер: US20120029522A1
Автор: Charles F. Leinberry, Peter F. Sharkey
Принадлежит: Knee Creations LLC

A method for treating arthritis of a joint includes identifying a bone lesion in a bone adjacent to the joint; and implanting in the bone a reinforcing member in or adjacent to the bone lesion. A kit for conducting the method includes: (a) at least one reinforcing member having a proximal face adapted to face the joint, a distal face adapted to face away from the joint, and a wedge-shaped edge adapted to pierce bone, wherein the at least one reinforcing member is planar and sterile; and (b) a container adapted to maintain the at least one reinforcing member sterile. Another kit includes: (a) a sterile fluid; (b) a syringe for injecting the fluid into a bone; (c) a curing agent adapted to cure the fluid to polymerize and/or cross-link; and (d) a container adapted to maintain the sterility of contents of the container.

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Номер записи: 2
09-02-2012 дата публикации

Osteoarthritis treatment and device

Номер: US20120035609A1
Автор: Charles F. Leinberry, Peter F. Sharkey
Принадлежит: Knee Creations LLC

A method for treating arthritis of a joint includes identifying a bone lesion in a bone adjacent to the joint; and implanting in the bone a reinforcing member in or adjacent to the bone lesion. A kit for conducting the method includes: (a) at least one reinforcing member having a proximal face adapted to face the joint, a distal face adapted to face away from the joint, and a wedge-shaped edge adapted to pierce bone, wherein the at least one reinforcing member is planar and sterile; and (b) a container adapted to maintain the at least one reinforcing member sterile. Another kit includes: (a) a sterile fluid; (b) a syringe for injecting the fluid into a bone; (c) a curing agent adapted to cure the fluid to polymerize and/or cross-link; and (d) a container adapted to maintain the sterility of contents of the container.

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Номер записи: 3
23-02-2012 дата публикации

Devices and methods for treating defects in the tissue of a living being

Номер: US20120046758A1
Автор: Douglas G. Evans, Russell T. Kronengold, Scott M. Goldman
Принадлежит: Evans Douglas G, Goldman Scott M, Kronengold Russell T

An implant for deployment in select locations or select tissue for regeneration of tissue is disclosed. The implant includes collagen and or other bio-resorbable materials, where the implant may also be used for therapy delivery.

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Номер записи: 4
08-03-2012 дата публикации

Expandable Fusion Device and Method of Installation Thereof

Номер: US20120059470A1
Автор: Mark Weiman
Принадлежит: Globus Medical Inc

The present invention provides an expandable fusion device capable of being installed inside an intervertebral disc space to maintain normal disc spacing and restore spinal stability, thereby facilitating an intervertebral fusion. In one embodiment, the fusion device includes a central ramp, a first endplate, and a second endplate, the central ramp capable of being moved in a first direction to move the first and second endplates outwardly and into an expanded configuration. The fusion device is capable of being deployed down an endoscopic tube.

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Номер записи: 5
22-03-2012 дата публикации

Method for inserting an artificial implant between two adjacent vertebrae along a coronal plane

Номер: US20120071984A1
Автор: Gary Karlin Michelson
Принадлежит: WARSAW ORTHOPEDIC INC

A method for inserting an artificial implant between two adjacent vertebrae along a corona plane,

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Номер записи: 6
05-04-2012 дата публикации

Anterior impacted bone graft and driver instruments

Номер: US20120083890A1
Автор: Dayna Buskirk, Eric C. Lange, Steven D. Deridder, Thomas V. McGahan
Принадлежит: Individual

Instrument and implants are disclosed which provide for insertion of an implant into an intervertebral disc space from multiple approaches to the spine. Specifically, as a preferred aspect of the invention the implant includes a tapered portion and the implant may be inserted from multiple approaches to the spine with the orientation and taper properly oriented in the disc space regardless of the approach.

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Номер записи: 7
19-04-2012 дата публикации

Intervertebral spinal implant, installation device and system

Номер: US20120095559A1
Автор: Damon L. Franklin, John C. Woods
Принадлежит: Individual

Improved interbody spinal implant devices and related instrumentation used for surgical installation of such implant devices for use in spinal fusion surgeries. The spinal implant devices are configured with apertures preferably used in conjunction with the instrumentation of the invention to improve the retention of bone graft material within the implant during installation. The invention also includes improved implants with deployable spike mechanisms.

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Номер записи: 8
26-04-2012 дата публикации

Implants and Methods for Spinal Fusion

Номер: US20120101582A1
Автор: Benjamin Verhage, Dan K. Ahlgren, Jared Arambula, Kamshad Raiszadeh, Michael C. Di Lauro, Michael Mindoro
Принадлежит: Nuvasive Inc

An implant is provided for performing spinal fusion. The implant includes an implant body having a leading side and a trailing side at opposing ends along a longitudinal axis. Between the leading side and trailing side are an upper surface, a lower surface, an anterior side, and a posterior side. At least one keel structure is provided extending from the implant body for penetration into an adjacent vertebral body. A trial sizer and keel cutter may be utilized to form keel channels within the vertebral body to receive the keel structure.

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Номер записи: 9
03-05-2012 дата публикации

Medical implant and method for photodynamic therpy

Номер: US20120109302A1
Автор: Bret Matthew Wilfong, Keith E. Miller
Принадлежит: WARSAW ORTHOPEDIC INC

An implant and method for insertion between adjacent vertebral members. The implant comprises an implant body with a base section having a plurality of base extensions, and an end cap adapted for selective axial positioning at a selected point on the base section. The end cap comprises a locking apertures and positioning apertures configured to engage corresponding base extensions, and a variable aperture slot extending through the end cap which is adapted to enable the end cap to resiliently deform as the end cap is positioned on the base section. The locking apertures and positioning apertures will prevent rotational movement of the end cap relative to the base section once the end cap is secured to the base section. The implant imparts end cap height and angulation to an adjacent vertebral body at the selected or desired point when the implant is positioned in the intervertebral space.

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Номер записи: 10
10-05-2012 дата публикации

Semi-biological intervertebral disc replacement system

Номер: US20120116514A1
Автор: Patricia K. Kuslich, Stephen D. Kuslich
Принадлежит: Spineology Inc

Disclosed is a system and method for a partially biological disc replacement that stimulates natural fibrous, cartilaginous or other tissue growth in the DDD cavity, resulting in a partial biological disc replacement. Multiplicities of fibronous pieces of fibro-cartilaginous tissue promoting material are inserted into the DDD cavity inducing tissue growth. The fibro-cartilaginous tissue

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Номер записи: 11
10-05-2012 дата публикации

Selectively Expanding Spine Cage, Hydraulically Controllable In Three Dimensions for Vertebral Body Replacement

Номер: US20120116518A1
Автор: Rudy Pretti, Thomas Grotz
Принадлежит: Coalign Innovations Inc

A selectively expanding spine cage has a minimized diameter in its unexpanded state that is smaller than the diameter of the neuroforamen through which it passes in the distracted spine. The cage conformably engages between the endplates of vertebrae to effectively distract the anterior disc space, stabilize the motion segments, eliminate pathologic spine motion, or effect vertebral body replacement. Expanding selectively (anteriorly, along the vertical axis of the spine) rather than uniformly, the cage height increases and holds the vertebrae with fixation forces greater than adjacent bone and soft tissue failure forces in natural lordosis. Stability is thus achieved immediately, enabling patient function by eliminating painful motion. The cage shape intends to rest proximate to the anterior column cortices securing the desired spread and fixation, allowing for bone graft in, around, and through the implant for arthrodesis whereas for arthroplasty it fixes to endpoints but cushions the spine naturally.

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Номер записи: 12
31-05-2012 дата публикации

Devices and Methods For Treating Bone

Номер: US20120136399A1
Автор: David W. Ankney, II Michael Lee Boyer, Jamie Calverley, Jody L. Seifert, Mark Adams, Nirali Patel, Paul W. Millhouse
Принадлежит: Globus Medical Inc

A device is disclosed for reducing a vertebral compression fracture, comprising a superior end plate and an inferior end plate disposed along a vertical axis. The superior end plate and the inferior end plate are slidably separable in a vertical direction along the vertical axis. An interior chamber is provided in fluid communication with a port extending from an exterior to the interior chamber. The device is deployable within a vertebral body and expandable within the vertebral body by injecting a flowable material into the interior chamber thereby displacing the superior and inferior end plates along the vertical axis.

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Номер записи: 13
14-06-2012 дата публикации

Apparatus and method for anchoring sutures

Номер: US20120150222A1
Автор: Edwin C. Bartlett
Принадлежит: Individual

A suture anchor having a conical surface and a bore in which an end of an insertion tool is inserted. The insertion end of the insertion tool is made of material having elastic properties. The bore and base of the suture anchor are angled with respect to the central axis of the suture anchor and preferably are parallel to each other. During insertion, the suture anchor is reoriented to fit into the hole, thereby bending the elastic end of the insertion tool. When the suture anchor is within cancellous bone tissue, the elastic properties of the insertion tool deploys the suture anchor to an orientation in which the suture anchor cannot fit through the bone hole, thereby firmly anchoring the suture anchor in the human bone.

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Номер записи: 14
21-06-2012 дата публикации

Bone substitute material

Номер: US20120157291A1
Автор: Anthony William Miles, Irene Gladys Turner, Paul Gittings Jonathan
Принадлежит: Mesuro Ltd

A method of fabricating a bone substitute material comprises the steps of providing a foam material ( 3 ) having an open cell structure, distorting the shape of the foam material ( 3 ) and holding the material in a distorted shape, coating the walls of the cells of the foam material with a ceramic slip ( 5 ), removing the foam material, and sintering the ceramic slip to form a bone substitute material that is approximately a positive image of the distorted foam material ( 3 ). In another method, a granular bone material is formed from a multiplicity of pieces of foam that are not distorted.

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Номер записи: 15
19-07-2012 дата публикации

Interbody containment implant

Номер: US20120185046A1
Автор: William F. Mckay
Принадлежит: WARSAW ORTHOPEDIC INC

An interbody containment implant includes a body configured for delivery along a surgical pathway and disposed adjacent vertebrae. The body defines a cavity. At least one biologically compatible agent is configured for disposal within at least the cavity. A barrier is connected to the body and configured to be deployed to prevent the agent from migrating into the surgical pathway. Methods of use are disclosed.

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Номер записи: 16
20-09-2012 дата публикации

Method of using instruments and interbody spinal implants to enhance distraction

Номер: US20120239151A1
Автор: Chad J. Patterson, Peter F. Ulrich, JR.
Принадлежит: Titan Spine Inc

A method of using an interbody spinal implant by implanting the spinal implant into a patient in need of the spinal implant. The method includes accessing the disc space of the patient and locating the center of the disc space. The disc space is incised by making a window in the annulus of the disc space for insertion of the spinal implant. The endplates are cleaned of all cartilage and the disc structure, which is encapsulated by the annulus, is removed while avoiding damage to the endplate structure of the vertebrae. Optionally a size-specific rasp is selected and the disc space is cleared of all soft tissue and cartilage. Optionally the disc space is distracted by sequentially expanding it with distractors of progressively increasing heights. A spinal implant having a pre-determined size sufficient to balance frictional fit and elongation of the annulus is selected and seated in the disc space.

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Номер записи: 17
04-10-2012 дата публикации

Compositions for bone tissue repair and uses thereof

Номер: US20120253470A1
Автор: Kevin A. Guze, Vinicius Souza Rodrigues
Принадлежит: Harvard College

The technology described herein relates to compositions for promoting bone growth or regeneration. The compositions described herein can comprise bioactive agents and scaffold materials.

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Номер записи: 18
18-10-2012 дата публикации

Intervertebral disc prosthesis, method for assembling, method for implanting prosthesis, and method for explanting

Номер: US20120265304A1
Автор: Peter L. Mayer
Принадлежит: Individual

Prosthesis for inserting into a damaged intervertebral disc. The prosthesis has an elongated tubular main prosthesis body with a length to fit laterally from one side of a disc to the other at its mid-plane. The main prosthesis body is composed of two parts transversely oriented and has a vertical height deliberately greater than the height of normal disc space. Heads having a vertical height greater than the vertical height of the main prosthesis body are mounted on the ends of the main prosthesis body.

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Номер записи: 19
25-10-2012 дата публикации

Plug components for bone tunnel

Номер: US20120271414A1
Автор: Osamu Masaki
Принадлежит: MMT Co Ltd

A component for satisfactorily plugging a bone tunnel formed in surgery such as ACL reconstruction by regenerating bone in a space portion of the bone tunnel (e.g., a bone tunnel for an arthroscope), is provided in order to solve the problems in the conventional technologies. The plug component is made of a calcium phosphate-based material, comprises a porous part having a porosity of 50 to 85%, and has a cylindrical shape such that one of its bottom surfaces forms an angle of 30 to 60 degrees to its central axis.

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Номер записи: 20
01-11-2012 дата публикации

Angled Bullet-Nose Banana Cage

Номер: US20120277866A1
Автор: Christine Rusbarsky, Jonathan Howe, Prakasam Kalluri, Thomas Martin
Принадлежит: DePuy Spine LLC

A banana-shaped cage adapted for use as an intervertebral fusion cage, wherein the leading direction of the nose of the banana cage is substantially in-line with the angle of the inserter shaft that inserts the cage into the disc space. It has been found that insertion of this cage requires lower insertion forces than the conventional cage whose leading direction substantially follows the arc of the banana curve.

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Номер записи: 21
06-12-2012 дата публикации

In-situ intervertebral fusion device and method

Номер: US20120310352A1
Автор: John D. Malone, Thomas M. DiMauro
Принадлежит: DePuy Spine LLC

An orthopedic device for implanting between adjacent vertebrae comprising: an arcuate balloon and a hardenable material within said balloon. In some embodiments, the balloon has a footprint that substantially corresponds to a perimeter of a vertebral endplate. An inflatable device is inserted through a cannula into an intervertebral space and oriented so that, upon expansion, a natural angle between vertebrae will be at least partially restored. At least one component selected from the group consisting of a load-bearing component and an osteobiologic component is directed into the inflatable device through a fluid communication means.

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Номер записи: 22
13-12-2012 дата публикации

Device for expandable spinal laminoplasty

Номер: US20120316647A1
Автор: Azadeh Farin
Принадлежит: Azadeh Farin

The invention relates to devices, implants, systems, techniques and methods for addressing certain conditions of the spine, including devices, implants, systems and methods for performing spinal laminoplasty or other expansion of the spinal canal. The devices of the invention are expandable in situ, providing greater versatility for surgeons performing various procedures where expansion of the spinal canal is desired.

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Номер записи: 23
20-12-2012 дата публикации

Methods and apparatuses for vertebral body distraction and fusion employing a coaxial screw gear sleeve mechanism

Номер: US20120323329A1
Автор: Andrew G. Fischer, Nicholas Ransom Powley, Omar F. Jimenez, Yefim Safris
Принадлежит: SpineX Tec LLC

Improved methods and apparatuses for vertebral body distraction and fusion in accordance with various embodiments of the present invention employ one or more coaxial screw gear sleeve mechanisms. In various embodiments, coaxial screw gear sleeve mechanisms include a post with a threaded exterior surface and a corresponding sleeve configured to surround the post, the corresponding sleeve having a threaded interior surface configured to interface with the threaded exterior surface of the post and a geared exterior surface. A drive mechanism can be configured to interface with the geared exterior surface of the sleeve, causing the device to distract.

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Номер записи: 24
27-12-2012 дата публикации

Bilayered bone graft device

Номер: US20120330434A1
Автор: Shinn Jyh Ding
Принадлежит: Individual

A bilayered bone graft device includes a core portion comprising deminernalized gelatin and a shell portion surrounding the core portion. The shell portion includes a calcium silicate and the deminernalized gelatin in a range of 1 to 30 weight percent, and the calcium silicate has a molar ratio of calcium to silicon ranging from 10 to 0.1. The core portion and the shell portion are bound by the deminernalized gelatin without using a binder. In one embodiment of the present invention, the core portion is configured to provide buffering for receiving an insertion, and the shell portion is configured to provide a load-bearing structure.

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Номер записи: 25
10-01-2013 дата публикации

Prosthetic implant support structure

Номер: US20130013080A1
Автор: Arlen D. Hanssen, David G. Lewallen
Принадлежит: Zimmer Inc

A prosthetic system that includes a prosthetic implant and a support structure secured to an inner surface of a cavity of a bone is disclosed. The support structure defines a channel that extends through the length of the support structure. The prosthetic implant is received in the channel, and a portion of the prosthetic implant is secured to an inner surface of the support structure by an adhesive. The support structure may comprise a pair of partially hemispherical components arranged in spaced apart relationship thereby defining the channel between the pair of components.

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Номер записи: 26
17-01-2013 дата публикации

Bi-directional fixating/locking transvertebral body screw/intervertebral cage stand-alone constructs with vertical hemi-bracket screw locking mechanism

Номер: US20130018470A1
Автор: Ahmnon D. Moskowitz, Mosheh T. MOSKOWITZ, Nathan C. Moskowitz, Pablo A. Valdivia Y. Alvarado
Принадлежит: ALVARADO Pablo A Valdivia Y, Moskowitz Ahmnon D, Moskowitz Mosheh T, Moskowitz Nathan C

A bi-directional fixating transvertebral (BDFT) screw/cage apparatus is provided. The BDFT apparatus includes an intervertebral cage including a plurality of internal angled screw guides, a plurality of screw members, and a cage indentation adjacent to the screw guides that independently or supplemented by other screw locking mechanisms prevents the screw members from pulling out of the internal angled screw guides. The internal angled screw guides orient a first screw member superiorly and a second screw member inferiorly. The intervertebral cage is adapted for posterior lumbar intervertebral placement, anterior lumbar intervertebral placement, anterio-lateral thoracic intervertebral placement, or anterior cervical intervertebral placement.

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Номер записи: 27
07-02-2013 дата публикации

Subchondral treatment of joint pain of the spine

Номер: US20130035761A1
Автор: Charles F. Leinberry, David L. Nichols, Hallett Mathews, Marc R. Viscogliosi, Peter F. Sharkey
Принадлежит: Knee Creations LLC

Methods for altering the natural history of degenerative disc disease and osteoarthritis of the spine are proposed. The methods focus on the prevention, or delayed onset or progression of, subchondral defects such as bone marrow edema or bone marrow lesion, and subchondral treatment to prevent the progression of osteoarthritis or degenerative disc disease in the spine and thereby treat pain.

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Номер записи: 28
07-02-2013 дата публикации

Spinal fusion device

Номер: US20130035763A1
Автор: David Krueger
Принадлежит: Individual

A spinal fusion device is disclosed. The spinal fusion device includes a first endplate configured for fitting within a disc space and engaging with a first vertebra and a second endplate configured for fitting within the disc space and engaging with a second vertebra. The two endplates are separated by a single spacer that is positioned between the first endplate and the second endplate and maintains a pre-determined distance between the first endplate and the second endplate. The spacer contains an anterior end, a posterior end, a first lateral side, a second lateral side opposite to the first lateral side, a first surface that engages with the first endplate, a second surface that engages with the second endplate. Also disclosed are methods and instruments for implanting the spinal fusion device.

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Номер записи: 29
28-02-2013 дата публикации

Bi-directional fixating transvertebral body screws and posterior cervical and lumbar interarticulating joint calibrated stapling devices for spinal fusion

Номер: US20130053962A1
Автор: Ahmnon D. Moskowitz, Mosheh T. MOSKOWITZ, Nathan C. Moskowitz, Pablo A. Valdivia Y. Alvarado
Принадлежит: Ahmnon D. Moskowitz, Mosheh T. MOSKOWITZ, Nathan C. Moskowitz, Pablo A. Valdivia Y. Alvarado

A self-drilling bone fusion screw apparatus is disclosed which includes at least first and second sliding boxes. A first screw member having a tapered end and a threaded body is disposed within the first sliding box, and a second screw member having a tapered end and a threaded body disposed within the second sliding box. An adjuster adjusts the height of the sliding boxes. The screw members are screwed into vertebral bodies in order to fuse the vertebral bodies together. A plurality of the self-drilling bone fusion screw apparatuses may be attached together and/or integrated via a plate or cage. Also disclosed is a cervical facet staple that includes a curved staple base and at least two prongs attached to the bottom surface of the curved staple base.

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Номер записи: 30
28-03-2013 дата публикации

Far lateral spacer

Номер: US20130079882A1
Автор: Dan Mcphillips, James Schwender, Joeseph Gleason, Steve Wolfe
Принадлежит: Individual

A PEEK spacer for use in the spine is disclosed. The PEEK spacer may be configured to fit through Kambin's Triangle and expand upon insertion.

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Номер записи: 31
28-03-2013 дата публикации

Irradiated Cortical Bone Sheet Allografts and Method of Forming Irradiated Cortical Bone Sheet Allografts

Номер: US20130079889A1
Автор: Deborah Marie SPILLMAN
Принадлежит: Individual

There is disclosed an irradiated cortical bone sheet allograft. In an embodiment, the allograft includes a unitary sheet of at least partially demineralized, irradiated cortical bone having a thickness, a width, and a length. The thickness of the unitary sheet of irradiated cortical bone is less the width and the length. In another embodiment, a method of forming the allograft includes obtaining a natural bone from a donor different than a recipient. The natural bone contains a layer of a cortical bone. The method includes cleaning the natural bone to produce a unitary sheet of cortical bone. The method includes at least partially demineralizing the unitary sheet of cortical bone. The method includes freezing the unitary into a frozen state within a sealed package. The method includes irradiating the unitary sheet in the frozen state within the sealed package to sterilize the cortical bone and produce the irradiated cortical bone sheet for implantation in the recipient other than the donor. Other embodiments are also disclosed.

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Номер записи: 32
11-04-2013 дата публикации

Sac for use in spinal surgery

Номер: US20130090734A1
Автор: Francis Pflum
Принадлежит: Individual

A method for fusing spinal bone is provided. The method comprises placing a sac between two or more adjacent sections of the spine to be fused, and filling the sac with bone tissue. The surfaces of the sac abutting the sections of the spine comprise porous material for allowing bone to grow between the spine and the sac. Surfaces of the sac not abutting the sections of the spine are nonporous to bodily fluids and thereby prevent premature deterioration of the bone tissue inside the sac. A sac for fusing spinal bone and a kit comprising the sac are also provided.

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Номер записи: 33
18-04-2013 дата публикации

Interbody Cage for Spinal Fusion and Method of Implanting Interbody Cages into Spines

Номер: US20130096683A1
Автор: II Richard A. Kube
Принадлежит: II Richard A. Kube

A spinal interbody fusion implant has an impact rod fitting that is configured and adapted to be connected to an impact rod during implantation of the implant. The implant also comprises one or more openings that are encircled by portions of the implant and that extend into the top of the implant and continue through to and out of the bottom of the implant. The top and bottom of the implant each have a load bearing footprint. Each of the load bearing footprints has a centroid that is closer to the leading end of the implant than to the trailing end of the implant. A method of implanting a spinal interbody fusion implant between two vertebrae of a spine comprises inserting the implant into a patient through a posterior incision and guiding the implant into a position between the two vertebrae using a pair of shims.

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Номер записи: 34
02-05-2013 дата публикации

Interbody implant

Номер: US20130110238A1
Автор: Gary Lindemann, Paula A. Nichter
Принадлежит: WARSAW ORTHOPEDIC INC

An interbody implant is provided. The interbody implant includes a body having a cavity configured to retain material deposited in the cavity. The cavity has an opening defining a passageway in communication with the cavity. The implant further includes a membrane disposed about the opening of the cavity having a first configuration covering the opening and a second configuration such that the membrane exposes the passageway in communication with the cavity.

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Номер записи: 35
02-05-2013 дата публикации

Spinal surgery implants and delivery system

Номер: US20130110239A1
Автор: Didier TOUBIA, DVIR Keren, Oded Loebl, Tzony Siegal
Принадлежит: Nonlinear Tech Ltd

A spinal surgery tool system including an elongated conduit and an implant is disclosed. The implant assumes a straight configuration within the elongated conduit and is deployable from the elongated conduit into a closed or nearly-closed loop configuration for deployment interposed between two tissue surfaces to define an enclosed volume. The conduit and the implant are configured such that, when the implant is deployed in the loop configuration, an opening formed in a proximal portion of the implant forms a contiguous channel with a passageway along the conduit so as to provide a continuous access channel along the elongated conduit into the enclosed volume.

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Номер записи: 36
16-05-2013 дата публикации

Self-deploying locking screw retention device

Номер: US20130123925A1
Автор: Chad J. Patterson, Peter F. Ullrich, Jr.
Принадлежит: Titan Spine Inc

A screw assembly and a spinal implant. The screw assembly includes a screw with a head and a shaft where a screw retention member is positioned beneath the head of the screw and substantially surrounds the shaft of the screw. The screw retention member is formed from a temperature-sensitive material. The screw retention member has a first contracted position adapted for inserting the screw through at least one hole in the spinal implant and a second expanded position adapted for retaining the screw within the at least one hole in the spinal implant. The screw retention member may be in the form of a coiled spring or a collar having a plurality of tabs.

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Номер записи: 37
30-05-2013 дата публикации

Support device and method of use

Номер: US20130138214A1
Автор: E. Skott Greenhalgh, John-Paul Romano
Принадлежит: FLEXMEDEX LLC

Devices and methods for orthopedic support are disclosed. The device can have a first rigid section hingedly attached to a second rigid section. The device can be curved or rotated around obstructions along an access path to a target site. The device can be delivered to an intervertebral location in a patient.

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Номер записи: 38
13-06-2013 дата публикации

Implant with Sensor

Номер: US20130150970A1
Автор: Gowriharan THAIYANANTHAN
Принадлежит: BASIX SPINE LLC

A spinal implant for supporting adjacent bones or vertebrae by insertion through a surgical opening with adjacent nerves is disclosed. The spinal implant may include a body and one or more conductors. The body is configured to be inserted through the surgical opening to fit between the two endplates of the adjacent vertebrae and to maintain spacing between the endplates. The conductor has at least a first and second ends. Extending through a portion of the body, the conductor's first end is exposed and accessible through the surgical opening. The second end is exposed and positioned to communicate with at least one of the nerves. The first end of the conductor is also configured to communicate with a monitori

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Номер записи: 39
20-06-2013 дата публикации

Expandable interbody implant and methods of use

Номер: US20130158664A1
Автор: Anthony J. Melkent, Keith E. Miller, Stanley T. Palmatier, William D. Armstrong
Принадлежит: WARSAW ORTHOPEDIC INC

An intervertebral implant is provided. The intervertebral implant comprises a first component comprising an outer tissue engaging surface and an inner surface. A second component is connected to the first component, and is relatively moveable thereform. The second component comprises an outer tissue engaging surface and an inner surface. The second component includes an actuator. A third component is disposed for engagement and is movable relative to the first and second components. The third component comprises at least a first ramp and a second ramp axially spaced apart from the first ramp. The actuator is engageable with the third component to effect axial translation of the wedge such that the ramps engage the inner surface of at least one of the first component and the second component to move the components between a first, collapsed configuration and a second, expanded configuration. Methods of use are disclosed.

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Номер записи: 40
27-06-2013 дата публикации

Lateral Cage with Integrated Plate

Номер: US20130166027A1
Автор: Jonathan Bellas
Принадлежит: DePuy Synthes Products Inc

An intervertebral fusion cage having a plate pivotally attached thereto. The plate and cage are pivotally coupled but move independently of each other. The plate is made up of two smaller plate halves: a superior plate half and an inferior plate half Both plate halves form the larger plate. The plates are joined using a cross pin that provides a pivot point about which the plate halves rotate. The same pin also joins the plate halves to the cage, thus allowing the plate halves to pivot about the cage. It is believed that the device of the present invention will reduce the difficulties in placing a lateral plate down a port and manipulating it into position. Mating the plate to the cage will reduce the chances of micromotion and improve fusion rate, resulting in improved patient outcomes.

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Номер записи: 41
27-06-2013 дата публикации

Osseous implant and methods of its making and use

Номер: US20130166039A1
Автор: Lori J. Shaw-Klein
Принадлежит: Micropen Technologies Corp

The present invention relates to an osseous implant for osteogenesis promotion and maintenance, the implant having an exposed surface, and the improvement comprising an electrical circuit attached to the osseous implant. At least a portion of the electrical circuit comprises a trace of conductive particles deposited on the exposed surface of the osseous implant. The present invention also relates to a method of promoting and maintaining osteogenesis by implanting the osseous implant into a subject. Current is passed through the electrical circuit under conditions effective to promote and maintain osteogenesis in the subject. Also disclosed is a method of making an osseous implant for osteogenesis promotion and maintenance.

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Номер записи: 42
25-07-2013 дата публикации

Bone graft delivery device

Номер: US20130190718A1
Автор: Rebecca Fingerhut
Принадлежит: Spinesmith Partners LP

Aspects of the claimed invention relate generally to devices for delivering bone graft compositions to implants that have been positioned between vertebral bodies during surgery and methods of using such devices. Embodiments of the invention provide ease of bone graft delivery in situ while providing an environment for the mixing of bone graft, insertion of the bone graft, and packing of the graft into the voids above and below the implant.

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Номер записи: 43
25-07-2013 дата публикации

Selectively Expanding Spine Cage With Enhanced Bone Graft Infusion

Номер: US20130190875A1
Автор: Damien J. Shulock, John E. Ashley, Rudy Pretti, Thomas Grotz
Принадлежит: Coalign Innovations Inc

A selectively expanding spine cage has a minimized cross section in its unexpanded state that is smaller than the diameter of the neuroforamen through which it passes in the distracted spine. The cage conformably engages between the endplates of the adjacent vertebrae to effectively distract the anterior disc space, stabilize the motion segments and eliminate pathologic spine motion. Expanding selectively (anteriorly, along the vertical axis of the spine) rather than uniformly, the cage height increases and holds the vertebrae with fixation forces greater than adjacent bone and soft tissue failure forces in natural lordosis. Stability is thus achieved immediately, enabling patient function by eliminating painful motion. The cage shape intends to rest proximate to the anterior column cortices securing the desired spread and fixation, allowing for bone graft in, around, and through the implant for arthrodesis whereas for arthroplasty it fixes to endpoints but cushions the spine naturally.

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Номер записи: 44
08-08-2013 дата публикации

Bone fusion device, system and method

Номер: US20130204371A1
Автор: Benjamin J. REMINGTON, Daniel E. Gerbec, Daniel R. Baker, Gary R. McLuen, Gregory C. Stalcup, Joseph N. Logan
Принадлежит: Individual

A bone fusion method, system and device for insertion between bones that are to be fused together in order to replace degenerated discs and/or bones, for example, the vertebrae of a spinal column. The bone fusion device comprises a frame and one or more extendable plates that are able to be angled, rotatable, adjustable, and have top profiles designed to correct and/or match the replaced discs/bones. The bone fusion device is able to be inserted between or replace the vertebrae by using a minimally invasive procedure wherein the dimensions and/or other characteristics of the bone fusion device are selectable based on the type of minimally invasive procedure.

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Номер записи: 45
22-08-2013 дата публикации

Prosthetic implant for ball and socket joints and method of use

Номер: US20130218282A1
Автор: Jessee Hunt
Принадлежит: 4Web Inc

A hip prosthesis includes an acetabular cup and a femoral component comprising a head and a stem, wherein the stem comprises a truss structure, the truss structure comprising a space truss comprising a plurality of planar truss units having a plurality of struts joined at nodes, wherein the web structure is configured to interface with bone tissue.

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Номер записи: 46
05-09-2013 дата публикации

Bone-Anchoring or Bone-Connecting Device that Induces a Strain Stimulus

Номер: US20130231706A1
Автор: Frank Heuer, Frank Trautwein, Guy MATGÉ, Jörg Franke, Michael Putzier, Ralph Kothe, Ulf Liljenqvist
Принадлежит: ACES INGENIEURGESELLSCHAFT MBH

The invention relates to an implant in the form of a bone-connecting device with an implant carrier, having at least two structure carriers for stimulating bone growth, the structure carriers can move relative to one another so that, due to a loading of the implant, a relative movement of the structure carriers occurs, the structure carriers furthermore contain structure elements that are arranged so that they define a plurality of partially open intermediate spaces, wherein a volume defined by these intermediate spaces and an immediate environment is deformed by the implant load, and a strain in the intermediate spaces and its immediate environment resulting from the deformation lies in the physiological range for bone growth.

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Номер записи: 47
26-09-2013 дата публикации

Method of manufacturing a composite interbody device

Номер: US20130247357A1
Автор: Scott K. Stanley, Theodore P. Bertele
Принадлежит: SB Technologies LLC

A method of manufacturing a composite interbody device includes assembling superior and inferior endplates, this including forming or layering micro-porous titanium on opposing sides of a solid titanium sheet. A first of the opposing sides provides a micro-porous bone interface layer and a second of the opposing sides provides a micro-porous core interface side. The solid titanium sheet therebetween forms a central barrier layer. The inferior and superior endplates are placed in a mold, on each side of a core cavity, with the core interface sides facing the core cavity and the bone interface sides facing away from the cavity. Molten plastic is injection-molded into the core cavity to form a plastic core between the endplates, the molten plastic extruding into pores of the microporous core interface sides. The plastic is set to bond the core with the endplates.

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Номер записи: 48
26-09-2013 дата публикации

Flanged interbody fusion device with fastener insert and retaining ring

Номер: US20130253655A1
Автор: Jason Blain
Принадлежит: Spinal Elements Inc

Methods and devices are disclosed for treating the vertebral column. An integrated fixation plate and spacer having a retaining structure within the screw holes of the fixation plate to resist backout of screws attaching the fixation plate to the bone is provided. A movable joint may be provided between the fixation plate and spacer. In some embodiments, a screw hole insert is also provided to resist shear forces acting between the screw and fixation plate. In some embodiments, an integrated fixation plate and spacer system is provided, comprising two or more integrated fixation plate and spacer implants, wherein the fixation plates of each implant has a complementary configuration to allow attachment of the implants at adjacent intervertebral spaces. Alternative fixation systems are also contemplated.

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Номер записи: 49
10-10-2013 дата публикации

Methods of building a body portion

Номер: US20130267026A1
Автор: Peter M. Bonutti
Принадлежит: P Tech LLC

An improved method of implanting cells in the body of a patient includes positioning viable cells on a support structure. One or more blood vessels may be connected with the support structure to provide a flow of blood through the support structure. A support structure may be positioned at any desired location in a patient's body. The support structure may be configured to replace an entire organ or a portion of an organ. An organ or portion of an organ may be removed from a body cells and/or other tissue is removed to leave a collagen matrix support structure having a configuration corresponding to the configuration of the organ or portion of an organ. Alternatively, a synthetic support structure may be formed. The synthetic support structure may have a configuration corresponding to a configuration of an entire organ or only a portion of an organ.

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Номер записи: 50
17-10-2013 дата публикации

Vertebral body spacer

Номер: US20130274885A1
Автор: Komei Kato, Shinichi Ohmori, Toshio Matsumoto, Yuzo Daigo
Принадлежит: Mitsubishi Materials Corp

A vertebral body spacer of the present invention is used by being inserted between a vertebral body and a vertebral body (intervertebral space). The vertebral body spacer has a block body constituted of titanium or a titanium alloy as a main component thereof, and provided with a pair of contact surfaces to be made contact with the vertebral body and the vertebral body. The block body includes a frame-shaped dense part and a porous part provided inside the dense part, and a porosity of at least a surface of the porous part is larger than a porosity of the dense part. According to the present invention, it is possible to maintain an appropriate size between the vertebral bodies (intervertebral space).

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Номер записи: 51
24-10-2013 дата публикации

Method for modifying the wettability and other biocompatibility characteristics of a surface of a biological material by the application of beam technology and biological materials made thereby

Номер: US20130282136A1
Автор: Joseph Khoury, Laurence B. Tarrant, Richard C. Svrluga, Sean R. Kirkpatrick, Stephen M. Blinn
Принадлежит: Joseph Khoury, Laurence B. Tarrant, Richard C. Svrluga, Sean R. Kirkpatrick, Stephen M. Blinn

A method of preparing a preformed bone shape for implantation provides irradiating at least a portion of a preformed bone shape by a Neutral Beam derived from a GCIB, and the preformed bone shape so irradiated.

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Номер записи: 52
31-10-2013 дата публикации

Joint replacement implant

Номер: US20130289729A1
Автор: Peter M. Bonutti
Принадлежит: BONUTTI SKELETAL INNOVATIONS LLC

An implant for one of partial and total replacement of an articulating joint between a first bone and a second bone. The implant has a joint component implant including a body and a head, the body including a first region spaced from the head and a second region proximate the head, the head including a convex bearing surface. At least a portion of the first region has a textured surface, the textured surface constructed of a foam metal material that is configured to promote bone in-growth into the textured surface, the body constructed of a metallic material and configured for attaching to the first bone, the first region tapering from a proximal end adjacent the second region toward a distal end.

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Номер записи: 53
21-11-2013 дата публикации

Spinal Implants for Rotationally Adjusting Vertebrae

Номер: US20130310937A1
Автор: Luiz Pimenta
Принадлежит: Nuvasive Inc

A spinal implant adapted to be positioned within a disc space between adjacent vertebrae includes a first intradiscal element, a second intradiscal element, and a coupling mechanism. The first and second intradiscal elements include respective first and second outer surfaces adapted to be positioned adjacent an endplate of respective first and second adjacent vertebrae. The first and second intradiscal elements further include respective first and second medial surfaces that are opposite the respective first and second outer surfaces, where the second medial surface is adapted to generally face the first medial surface upon assembly of the first intradiscal element with the second intradiscal element. The coupling mechanism is associated with the first and second medial surfaces and is adapted to provide relative rotational movement between the first and second intradiscal elements in a plane generally parallel with the first and second medial surfaces.

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Номер записи: 54
21-11-2013 дата публикации

Spine surgery method and implant

Номер: US20130310939A1
Автор: Henry F. Fabian, Larry A. Cicoretti
Принадлежит: Individual

An implant has a first contact surface to contact a first vertebral body endplate and a second contact surface to contact a second vertebral body endplate adjacent the first vertebral body. The implant is deployable, when positioned within an intradiscal space between the first and second vertebral bodies, from a first non-expanded condition where the first contact surface has a first effective footprint area A 1 to a second expanded condition where the first contact surface has a second effective footprint area A 2. The ratio A 2/ A 1 is at least 1.05.

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Номер записи: 55
09-01-2014 дата публикации

Spinal spacer devices, tools, and methods

Номер: US20140012387A1
Автор: Joseph Ting, Paul Glazer
Принадлежит: Individual

A spacer device for spinal fixation, such as in corpectomies and discectomies, includes a core and two end plates mounted to the core. One end plate is mounted to each respective end of the core. The core can be configured and adapted to be adjustable to allow for contraction and/or distraction of the end plates. The end plates can include apertures therethrough to facilitate osseointegration of the spacer device within a patient's spine. The angle of the endplates can each be adjusted with respect to the core of the spacer device, for example to accommodate lordosis. A containment mesh is included around the spacer device, wrapping circumferentially around the end plates, and spanning from end plate to end plate. The containment mesh defines a containment volume between the end plates for containing bone replacement materials such as allograft or man-made materials.

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Номер записи: 56
16-01-2014 дата публикации

Articulating Interbody Cage and Methods Thereof

Номер: US20140018922A1
Автор: James F. Marino, Jamil Elbanna
Принадлежит: Trinity Orthopedics LLC

Disclosed herein are devices ( 100 ), systems and methods of use relating to articulating interbody cages. In one aspect, disclosed is an intervertebral device ( 100 ) for use in a human spine including an anterior end ( 104 ); a posterior end ( 102 ); and at least four peripheral walls ( 22,24,26 ). The peripheral walls ( 26 ) define an interior volume surrounding a midline of the device and include a superior wall ( 22 ), an inferior wall ( 24 ) and a pair of opposing, generally trapezoidal-shaped sidewalls. Each of the trapezoidal-shaped sidewalls ( 26 ) includes an internal hinge element ( 60 ) that is rotatable from a first configuration to at least a second configuration such that the device is expandable in first dimension. Each of the internal hinge elements includes an axis that is coplanar with the midline of the device.

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Номер записи: 57
30-01-2014 дата публикации

Mesh spacer hybrid

Номер: US20140031939A1
Автор: Bryan Becker, Clint Boylan, Craig Kuhns, Dan Mcphillips, Michael Wang, Steve Wolfe, Tim Walnofer
Принадлежит: Individual

A modular implant for performing an intervertebral fusion on adjacent vertebral bodies in a patient including a first spacer portion, a second spacer and a container having a first end and a second end, the first end of the container constructed to operably engage a first spacer and the second end of the container constructed to operably engage the second spacer.

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Номер записи: 58
30-01-2014 дата публикации

Bone graft materials and methods

Номер: US20140031950A1
Автор: Duraid S. Antone, Russell L. Cook
Принадлежит: Biostructures LLC

Compositions, materials, methods and kits for bone grafting are described. In some embodiments, a bone graft composition includes about 15% to about 20% by weight collagen, about 55% to about 70% by weight bioactive glass, and about 15% to about 30% by weight a calcium phosphate. The bioactive glass and the calcium phosphate together are about 80% to about 85% by weight of the bone graft composition. In some embodiments, a bone graft composition includes a collagen matrix and a plurality of bioactive glass particulates dispersed throughout the collagen matrix. The collagen matrix is about 20% to about 60% by weight of the bone graft composition, and the bioactive glass is about 40% to about 80% of the bone graft composition. In some embodiments, a majority of the bioactive glass particulates are about 53 μm to about 425 μm in size.

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Номер записи: 59
13-02-2014 дата публикации

Spinal stabilization system and method

Номер: US20140046445A1
Автор: William A. Brennan
Принадлежит: Individual

A method for stabilizing the spine at the level of one or more vertebrae includes the step of inserting a pedicle connector through the pedicle of a vertebra from one of the anterior side and posterior side of the vertebra to the other of the anterior side and the posterior side of the vertebra. The pedicle connector is secured to a stabilization construct positioned adjacent to either the anterior side or posterior side of the vertebra. The process is repeated for the opposite side of the pedicle connector. A system for stabilizing the spine and a pedicle connector are also disclosed.

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Номер записи: 60
20-02-2014 дата публикации

Stand alone interbody fixation system

Номер: US20140052260A1
Автор: Breana McKenny, Jeffery Bash, Joseph Aferzon
Принадлежит: Alphatec Spine Inc

An interbody spacer system for insertion between a first vertebra and a second vertebra according to the principles of the present disclosure includes and interbody spacer and a first curved blade. The interbody spacer includes an outer wall and a first surface for engaging an endplate of the first vertebra and a second surface for engaging an endplate of the second vertebra. A first entry aperture in the outer wall and a first exit aperture on the first surface communicate with a first curved path extending therebetween. The first curved blade enters the first entry aperture and exits through the first exit aperture to secure the spacer to the first vertebra.

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Номер записи: 61
20-02-2014 дата публикации

Intervertebral Implant Having Extendable Bone Fixation Members

Номер: US20140052262A1
Автор: Darrell C. Brett
Принадлежит: Individual

An intervertebral implant is configured to be fixed in an intervertebral space defined by a first vertebral body and a second vertebral body. The intervertebral implant includes an implant body sized to be inserted into an intervertebral space, and a fixation assembly configured to be attached to the implant body. The fixation assembly includes a housing that defines a first vertebral body facing surface and a second vertebral body facing surface spaced from the first vertebral body facing surface along a transverse direction. The fixation assembly further includes at least one fixation member supported by the housing and movable from a retracted position to an extended position, whereby in the extended position the fixation member extends out from the housing and into one of the vertebral bodies.

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Номер записи: 62
06-03-2014 дата публикации

Method for bone repair

Номер: US20140067078A1
Автор: Ching-Chuan Jiang, Chun-Jen Liao, Pei-Chi Hsu, Shih-Jui Han, Sung-Ching Chen
Принадлежит: Industrial Technology Research Institute ITRI

A bone repairing kit including a drilling device, a pushing device, a clamping member and a hole saw. An end of a tube body of the drilling device is a knife portion. When the tube body rotates with respect to a femur, a bone column is cut by the knife portion and located in the tube body. The pushing device includes a hollow tube and a push bar. The hollow tube is for receiving the tube body. The push bar is for touching and pushing the bone column in the tube body. The clamping member is for clamping the bone column. The hole saw includes a receiving body and cutting knives. The receiving body has a recess for receiving an end of the bone column. The cutting knives surrounding on an inner wall of the recess are for cutting an edge of the end of the bone column.

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Номер записи: 63
20-03-2014 дата публикации

Fusion cage with combined biological delivery system

Номер: US20140081279A1
Автор: Edward John Grimberg, JR., Jeffrey B. Kleiner
Принадлежит: Spinal Surgical Strategies LLC

The present invention relates to an apparatus and method for near-simultaneous and integrated delivery of bone graft material during the placement of surgical cages or other medical implants in a patient's spine. The integrated fusion cage and graft delivery device according to various embodiments delivers and disperses biologic material through a fusion cage to a disc space and, without withdrawal from the surgical site, may selectably detach the fusion cage for deposit to the same disc space. The integrated fusion cage and graft delivery device is formed such that a hollow tube and plunger selectively and controllably place bone graft material and a fusion cage in or adjacent to the bone graft receiving area.

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Номер записи: 64
20-03-2014 дата публикации

Spinal interbody spacer device and methods of using same

Номер: US20140081404A1
Автор: A. Joshua Appel, Marc C. Jacofsky
Принадлежит: CENTER FOR ORTHOPEDIC RESEARCH AND EDUCATION Inc

A method is provided for manipulating a spinal body spacer for use in spinal surgery on a patient. The method includes attaching a placement tool to the spinal body spacer and manipulating the placement tool so as to locate the spinal body spacer in a desired location. The placement tool can by removed by unscrewing the placement tool from a threaded receiving aperture of the spinal body spacer. The method also includes passing a tip of an extraction tool through the threaded receiving aperture of the spinal body spacer, the tip of the extraction tool having at least one tab. The tip of the extraction tool is rotated such that the at least one tab of the tip of the extraction tool passes through keyways of the spacer and extends into the interior space of the spinal body spacer.

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Номер записи: 65
10-04-2014 дата публикации

Non-Resorbable Plugs

Номер: US20140100665A1
Автор: Austin GRAY
Принадлежит: PRESIDIUM BIOMEDICAL LLC

A non-resorbable wound dressing can include a plug made from polytetrafluoroethylene (PTFE). The plug can have a three-dimensional shape. The plug can be substantially cylindrical. The PTFE can have a high density and be expanded. The PTFE can be non-porous or have a porosity of less than about 0.4 microns. The PTFE can also be unsintered and unexpanded. A method of regenerating alveolar bone includes placing a PTFE plug in a cavity formed in an alveolar bone. Placing the plug in the cavity can include contacting at least a portion of a peripheral surface of the plug with the gingival tissue surrounding the cavity. The method can also include inserting a bone graft material in the cavity before placing the plug in the cavity.

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Номер записи: 66
07-01-2021 дата публикации

BONE MATERIAL HYDRATION DEVICES AND METHODS

Номер: US20210000518A1
Автор: Dewey Jonathan M., Diegmueller Jared J., Kalpakci Kerem N., Shimko Daniel A., Vasquez Erick
Принадлежит:

A device for hydrating particulate bone material is provided. The device comprises a tubular member having an interior surface and an exterior surface. The interior surface is configured to receive the particulate bone material and a hydration fluid. The exterior surface has a plurality of pores configured to allow the hydration fluid to flow into the interior surface of the tubular member and hydrate the particulate bone material. The plurality of pores are smaller in size than the particulate bone material. Methods of dispensing particulate the bone material are also provided. 1. A device for hydrating particulate bone material , the device comprising a tubular member having an interior surface and an exterior surface , the interior surface configured to receive the particulate bone material and a hydration fluid , the exterior surface having a plurality of pores configured to allow the hydration fluid to flow into the interior surface of the tubular member and hydrate the particulate bone material , the plurality of pores being smaller in size than the particulate bone material , wherein the plurality of pores have a pore size from about 10 to about 100 microns.2. The device of claim 1 , wherein (i) the tubular member comprises a proximal end opening configured to receive the particulate bone material; (ii) the tubular member comprises a distal end opening configured to dispense the particulate bone material; (iii) or a combination thereof.3. The device of claim 1 , wherein the tubular member comprises a removable distal end configured to form a distal end opening to dispense the particulate bone material.4. The device of claim 2 , wherein the tubular member is configured to slidably engage a cannula and the proximal end opening of the tubular member is configured to slidably receive a plunger.5. The device of claim 4 , wherein the proximal end opening of the tubular member comprises a collar configured to engage the cannula claim 4 , or a proximal end of the ...

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Номер записи: 67
03-01-2019 дата публикации

FILTRATION DEVICE

Номер: US20190000522A9
Автор: McKay William F.
Принадлежит:

A device for separating particulate matter (e.g., cells) from a liquid including a housing defining an elongate chamber disposed between a receiving end and a dispenser end, a plunger slidably inserted within the chamber from the receiving end, an upper disc and a lower disc each independently slidably affixed to the plunger, the lower disc facing the dispenser end and including at least one filter arrangement, and a liquid including particulate matter disposed within the chamber when the upper disc and lower disc are in an aspiration mode. The upper disc is independently slidable with respect to the lower disc to achieve a filtration mode. 117.-. (canceled)18. A method for separating particulate matter from a liquid comprising: providing a housing defining an elongate chamber disposed between a receiving end and a dispenser end;providing a plunger slidably inserted within the chamber from the receiving end; providing an upper disc and a lower disc each independently slidably affixed to the plunger, the lower disc facing the dispenser end and including at least one filter arrangement; sliding the upper and lower discs upwards towards the receiving end for aspirating a liquid including particulate matter within the chamber; affixing a cap to the dispensing end; and sliding the lower disc downwards to achieve a filtration mode for separating the particulate matter from the liquid so as to cause the upper disc to slide toward the receiving end.19. A method of claim 18 , wherein achieving the filtration mode comprises dynamically forming an upper compartment containing filtrate of the liquid and dynamically forming a lower compartment containing a concentrated liquid comprising separated particulate matter and the method further comprises removing the cap and sliding the upper disc downwards to achieve a concentrated liquid expulsion mode.20. A method of claim 19 , wherein the upper compartment is formed between the upper disc and the lower disc and the lower ...

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Номер записи: 68
07-01-2016 дата публикации

SPINE SURGERY METHOD AND IMPLANT

Номер: US20160000574A9
Автор: Cicoretti Larry A., Fabian Henry F.
Принадлежит:

An implant has a first contact surface to contact a first vertebral body endplate and a second contact surface to contact a second vertebral body endplate adjacent the first vertebral body. The implant is deployable, when positioned within an intradiscal space between the first and second vertebral bodies, from a first non-expanded condition where the first contact surface has a first effective footprint area A to a second expanded condition where the first contact surface has a second effective footprint area A The ratio AA is at least 1.05. 140-. (canceled)41. A method of placing an implant , having first and second vertebral body endplate contact surfaces , into an intradiscal space between first and second adjacent vertebral bodies and deploying the implant while within the intradiscal space , comprising the steps of:(A) providing the implant with a first member and a second member pivotally attached to the first member, providing a first opening in the first member and a pin positioned in the second member;(B) distracting the intradiscal space between the first and second adjacent vertebral bodies;{'b': '1', '(C) inserting the implant into the intradiscal space in a first non-expanded condition where the first vertebral body endplate contact surface has a first effective footprint area A and the first vertebral body endplate contact surface faces the first vertebral body and the second vertebral body endplate contact surface faces the second vertebral body;'}{'b': 2', '2', '1, '(D) pivoting the second member with respect to the first member to deploy the implant within the intradiscal space to a second expanded condition where the first vertebral body endplate contact surface has a second effective footprint area A and the ratio A/A is at least 1.05; and,'}(E) positioning at least a portion of the pin within the first opening to lock the position of the second member with respect to the first member to prevent the second member from pivoting with respect to the ...

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Номер записи: 69
07-01-2021 дата публикации

BIOMIMETIC PLYWOOD MOTIFS FOR BONE TISSUE ENGINEERING

Номер: US20210000602A1
Автор: KUMTA PRASHANT N., ROY ABHIJIT, YU GARY
Принадлежит: University of Pittsburgh - of the Commonwealth System of Higher Education

The invention relates generally to generation of biomimetic scaffolds for bone tissue engineering and, more particularly, to multi-level lamellar structures having rotated or alternated plywood designs to mimic natural bone tissue. The invention also includes methods of preparing and applying the scaffolds to treat bone tissue defects. The biomimetic scaffold includes a lamellar structure having multiple lamellae and each lamella has a plurality of layers stacked parallel to one another. The lamellae and/or the plurality of layers is rotated at varying angles based on the design parameters from specific tissue structural imaging data of natural bone tissue, to achieve an overall trend in orientation to mimic the rotated lamellar plywood structure of the naturally occurring bone tissue. 1. A method of preparing a biomimetic scaffold , comprising:obtaining a scaffold material comprising a material selected from the group consisting of metal, metal alloy, polymer, ceramic, and composites and blends thereof; forming the scaffold material into a plurality of layers;', 'stacking the plurality of layers; and', 'aligning the plurality of layers; and, 'conducting an additive manufacturing process, comprisingrotating or alternating one or more of the plurality of layers to achieve an overall trend that mimics angular displacement of lamella in a rotated plywood lamellar structure of natural bone tissue.2. The method of claim 1 , further comprising:performing a structural imaging analysis of natural bone tissue comprising a rotated or an alternated plywood lamellar structure;employing data from the structural imaging analysis to specify design parameters of the biomimetic scaffold and to determine angular displacement of lamella in the rotated or alternated plywood lamellar structure.3. The method of claim 1 , wherein the scaffold material exhibits one or more properties selected from the group consisting of biodegradable claim 1 , bioresorbable claim 1 , bioabsorbable claim 1 ...

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Номер записи: 70
07-01-2021 дата публикации

IMPLANTABLE DEVICES

Номер: US20210000611A9
Автор: Converse Gabriel L., Roeder Ryan K., Smith Stephen M.
Принадлежит:

Implantable devices for orthopedic, including spine and other uses are formed of porous reinforced polymer scaffolds. Scaffolds include a thermoplastic polymer forming a porous matrix that has continuously interconnected pores. The porosity and the size of the pores within the scaffold are selectively formed during synthesis of the composite material, and the composite material includes a plurality of reinforcement particles integrally formed within and embedded in the matrix and exposed on the pore surfaces. The reinforcement particles provide one or more of reinforcement, bioactivity, or bioresorption. 1. An implantable device comprising: (a) a central region, and', '(b) an outer region,', 'at least one of the two regions comprising a porous reinforced composite scaffold material that comprises a thermoplastic polymer matrix, and a plurality of reinforcement particles distributed throughout the thermoplastic polymer matrix, and a substantially continuously interconnected plurality of pores that are distributed throughout the thermoplastic polymer matrix, each of the plurality of pores defined by voids interconnected by struts,', (i) a porous reinforced composite scaffold material that comprises a thermoplastic polymer matrix, and a plurality of reinforcement particles distributed throughout the thermoplastic polymer matrix, and a substantially continuously interconnected plurality of pores that are distributed throughout the thermoplastic polymer matrix, each of the plurality of pores defined by voids interconnected by struts, and', '(ii) a non-porous reinforced composite material that comprises a thermoplastic polymer matrix, and a plurality of reinforcement particles, 'and the other of the at least two regions comprising one of'}, 'distributed throughout the thermoplastic polymer matrix, 'at least two regions comprising,'}wherein the porosity of the central region is different from the porosity of the outer region.2. An implantable device according to claim 1 , ...

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Номер записи: 71
04-01-2018 дата публикации

Method for fusing a human or animal joint as well as fusion device and tool set for carrying out the method

Номер: US20180000592A1
Автор: Andrea Müller, Elmar Mock, Jorg Mayer, Mario Lehmann, Milica Berra, Stephanie Mehl, Urs Weber
Принадлежит: WW Tech AG

The fusion device for fusing a synovial joint of a human or animal patient, in particular a human facet joint, finger joint or toe joint, includes two pin-shaped anchorage portions and arranged therebetween a stabilization portion. The anchorage portions include a thermoplastic material which is liquefiable by mechanical vibration. The stabilization portion preferably has a surface which is equipped for enhancing osseointegration. The anchorage portions have a greater thickness and a greater depth than the stabilization portion. Then the fusion device is pushed between the articular surfaces and mechanical vibration, in particular ultrasonic vibration, is applied to the proximal face of the fusion device. Thereby the liquefiable material is liquefied where in contact with the bone tissue and penetrates into the bone tissue, where after re-solidification it constitutes a positive fit connection between the fusion device and the bone tissue.

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Номер записи: 72
04-01-2018 дата публикации

DEMINERALIZED BONE FIBER COMPOSITION FOR USE IN MINIMALLY INVASIVE SURGERY

Номер: US20180000595A1
Автор: Carter Andrew J., Scarborough Nelson L., Scarborough Oliver
Принадлежит: Theracell, Inc.

A bone repair composition and methods thereof include bone fibers made from cortical bone in which a plurality of bone fibers are made into various implant shapes conducive to introduction into a patient through minimally invasive surgery. The bone fiber compositions may be in the form of a pellet or cylinder. A method includes producing the bone fiber graft efficiently with control of key parameters of cohesiveness, rehydration and swelling of the bone fiber graft. Another method includes introducing the bone fiber graft into the cannula efficiently. A method is also provided to allow introduction of a bone graft into a patient by placing the implant in a tube and expelling it through the action of a plunger. 1. A bone repair composition , comprising:a plurality of fibers cut from demineralized bone in a form of a pellet, the pellet having an outermost layer of bone fibers which are annealed.2. The bone repair composition of claim 1 , wherein the outermost layer of bone fibers are annealed by heating and/or dehydrothermal treatment.3. The bone repair composition of claim 1 , wherein the outermost layer of bone fibers are annealed by chemically combining a hydroxy group from a functional group of a collagen molecule of the outermost layer of bone fibers and a hydrogen ion from a functional group of another collagen molecule of the outermost layer of bone fibers.4. The bone repair composition of claim 1 , wherein the outermost layer of bone fibers are annealed by heating the bone fibers in a metallic mold.5. The bone repair composition of claim 4 , wherein the metallic mold is stainless steel.6. A method of making a bone repair composition for minimally invasive surgery claim 4 , comprising:demineralizing cortical bone to form demineralized bone;repeatedly cutting the demineralized bone to form a plurality of bone fibers; andadding the plurality of bone fibers to a mold to form a mold of bone fibers.7. The method of claim 6 , wherein the mold comprises an elongated ...

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Номер записи: 73
03-01-2019 дата публикации

Scaffold with cortical wall

Номер: US20190000603A1
Автор: Hanna TIAINEN, Havard J. Haugen, Jan Eirik Ellingsen, S. Petter Lyngstadaas
Принадлежит: CORTICALIS AS

The present disclosure is directed to a titanium dioxide scaffold provided with a nanoporous outer layer which can function as a cortical wall, inhibiting growth of soft tissue into the scaffold and increasing its mechanical strength. The disclosure is also directed to a process for producing such a nanoporous outer layer and the application of the titanium dioxide scaffold with the nanoporous outer layer as a medical implant.

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Номер записи: 74
03-01-2019 дата публикации

INTRAOPERATIVE CUSTOM VOID FILLING METHODS, SYSTEMS AND APPARATUSES

Номер: US20190000629A1
Автор: Winslow Nathan A.
Принадлежит:

Methods, systems and apparatuses for treating a defect in a bone that forms at least a portion of a joint of a patient are disclosed. According to one example, a system including a first prosthesis, a second prosthesis and an alignment guide is disclosed. The first prosthesis can comprise a formable material. The second prosthesis can have a stock construction and can be configured to be implanted in the joint on at least a portion of the first prosthesis once the first prosthesis is formed to take a shape of and substantially fill a volume of the defect. The alignment guide can be configured to couple to the second prosthesis to retain the second prosthesis in a desired position and a desired orientation in the joint on the at least the portion of the first prosthesis. 1. A system for treating a defect in a bone that forms at least a portion of a joint of a patient , the system comprising:a first prosthesis comprising a formable material;a second prosthesis having a stock construction, the second prosthesis configured to be implanted in the joint on at least a portion of the first prosthesis once the first prosthesis is formed to take a shape of and substantially fill a volume of the defect; andan alignment guide configured to couple to the second prosthesis to retain the second prosthesis in a desired position and a desired orientation in the joint on the at least the portion of the first prosthesis.2. The system of claim 1 , wherein the first prosthesis comprises one or more of a bone graft claim 1 , bone claim 1 , and a synthetic bone putty.3. The system of claim 1 , wherein the first prosthesis in combination with the alignment guide provide for the desired position and the desired orientation of the second prosthesis relative to the joint.4. The system of claim 1 , further comprising a first mold configured to form the first prosthesis claim 1 , wherein the first mold is formed based on imaging data obtained using a medical imaging technique performed on the ...

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Номер записи: 75
03-01-2019 дата публикации

VARIABLE LORDOSIS SPACER AND RELATED METHODS OF USE

Номер: US20190000643A1
Автор: Burkhardt Alex, Glerum Chad, Weiman Mark
Принадлежит:

An expandable fusion device may include a first endplate and a second endplate. The expandable fusion device may also include first and second ramps configured to mate with both the first and second endplates. An inserter instrument includes an outer shaft having a bore extending longitudinally therethrough and an inner shaft extending through the bore in the outer shaft. The outer shaft is configured to engage the first or second opening in the second ramp, and the inner shaft is configured to engage the corresponding first or second opening in the first ramp to control implant height and/or lordotic angle. 1. A medical system comprising: an upper endplate;', 'a lower endplate opposed to the upper endplate;', 'a first ramp positioned between the upper endplate and the lower endplate, wherein the first ramp includes a first upper angled surface that engages the upper endplate and a first lower angled surface that engages the lower endplate;', 'a second ramp positioned between the upper endplate and the lower endplate, wherein the second ramp includes a second upper angled surface that engages the upper endplate and a second lower angled surface that engages the lower endplate; and', 'an actuation mechanism insertable into the first ramp and the second that causes expansion between the upper endplate and the lower endplate,', 'wherein the first ramp includes a first bore for receiving the actuation mechanism and a second bore for receiving graft material,', 'wherein the second ramp includes a second bore for receiving the actuation mechanism and the second bore for receiving graft material,', 'wherein the first bore of the first ramp is substantially aligned with first bore of the second ramp, and the second bore of the second ramp is substantially aligned with the second bore of the second ramp., 'an expandable device comprising2. The system of claim 1 , wherein the first ramp is configured to move toward the second ramp to cause expansion between the upper endplate ...

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Номер записи: 76
04-01-2018 дата публикации

Methods and Apparatus for Performing Spine Surgery

Номер: US20180000604A1
Автор: Morris Andrew, Pimenta Luiz, Serra Michael, Snider Brian
Принадлежит: NUVASIVE, INC.

Systems and methods are described for correcting sagittal imbalance in a spine including instruments for performing the controlled release of the anterior longitudinal ligament through a lateral access corridor and hyper-lordotic lateral implants. 1. A method for correcting saggital imbalance of a lumbar spine , comprising the steps of:inserting an access system along a lateral, trans-psoas path to a target site on the lumbar spine to create an operative corridor to the target site;preparing the intervertebral space between first and second vertebra of the lumbar spine for receipt of an intervertebral implant, the intervertebral space being at least partially defined by an anterior aspect, a posterior aspect, and opposing first and second lateral aspects;advancing a tissue retractor through the operative corridor along the lateral, trans-psoas path to a protective position in which a protective head of the tissue retractor is positioned between the Anterior Longitudinal Ligament (ALL) and the anterior vasculature, the tissue retractor protective head including an inner surface that faces the ALL and an outer surface that that faces the anterior vasculature when the tissue retractor is in the protective position, a distal end of the protective head being curved such that the distal end curves around the anterior aspect of the target site,advancing a cutting blade along the inner surface of the tissue retractor protective head and severing the Anterior Longitudinal Ligament (ALL) with the cutting blade; andadvancing and intervertebral implant through the operative corridor along the lateral, trans-psoas path and depositing the intervertebral implant into the intervertebral disc space.2. The method of claim 1 , wherein the intervertebral implant includes an upper surface that contacts the first vertebra and a lower surface that contacts the second vertebra claim 1 , a distal wall claim 1 , a proximal wall claim 1 , an anterior sidewall that faces anteriorly claim 1 , ...

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Номер записи: 77
04-01-2018 дата публикации

INTERBODY FUSION IMPLANT

Номер: US20180000610A1
Автор: Mantri Kaustubh
Принадлежит:

An intervertebral implant can include a core and a flexible end plate. The core can have a core body that is elongate along a first direction and defines first and second outer surfaces. The flexible end plate can define an inner surface and an opposed bone facing surface that is configured to abut a vertebral body. The flexible end plate can be coupled to the core such that at least a portion of the inner surface faces the first outer surface and is spaced from the first outer surface. The flexible end plate is configured to resiliently flex toward a compressed configuration such that as the flexible end plate flexes toward the compressed configuration, a first end moves relative to the core along the first direction and the portion of the inner surface moves toward the first outer surface. 1. An intervertebral implant comprising:a core defining a rear end and a front end that is spaced from the rear end along an insertion direction;an end plate that defines a bone facing surface and an inner surface that is opposite the bone facing surface, the end plate further defining a first attachment member and a second attachment member that is spaced from the first attachment member, the first and second attachment members being movably coupled to the core such that at least a portion of the inner surface faces the core and is spaced from the core a first distance along a first direction that is substantially perpendicular to the insertion direction,wherein the end plate is configured to resiliently move toward the core along the first direction such that 1) the portion of the inner surface is spaced from the core a second distance along the first direction that is less than the first distance, and 2) at least one of the first and second attachment members moves along the core.2. The intervertebral implant of claim 1 , wherein the at least one of the first and second attachment members moves along the core along the first direction.3. The intervertebral implant of claim 1 ...

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Номер записи: 78
05-01-2017 дата публикации

Intersomatic cage

Номер: US20170000620A1
Автор: Michael Perisic
Принадлежит: CARPE CONSULTANTS SARL

The invention relates to an intersomatic cage comprising a body ( 3 ) and a part ( 2 ) that is designed to dilate the intersomatic space between two vertebrae ( 8, 8 ′) by rotating the cage so that the cage ( 1 ) can be inserted into the space. The body ( 3 ) has a prism shape with a substantially planar upper surface ( 6 ) which can bear against the superior vertebral endplate ( 8 ) and a substantially planar lower surface ( 6 ′) which can bear against the inferior vertebral endplate ( 8 ′).

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Номер записи: 79
01-01-2015 дата публикации

Vertebral body replacement apparatus

Номер: US20150005880A1
Автор: Roman RANDEGGER, Samantha Popa, Tom Overes
Принадлежит: DePuy Synthes Products Inc

A vertebral body replacement apparatus includes an outer body member having a first end, a second end, and an opening, and an inner body member having a first end, a second end, and an inner surface defining an opening. The first end of the inner body member is received in the opening of the outer body member such that the inner body member and the outer body member are movable relative to one another. A support member has a first end secured within the inner body member and a second end extending a distance beyond the inner body member. The second end of the support member deflects relative to the first end of the outer body member in response to a force applied thereto and returns to a substantially non-deflected condition upon release of the force.

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Номер записи: 80
12-01-2017 дата публикации

COMPRESSION RESISTANT IMPLANTS INCLUDING AN OXYSTEROL AND METHODS OF USE

Номер: US20170007407A1
Автор: Drapeau Susan J., Harrington Roger E., Jacobs Jerbrena C., Reves Benjamin T., Scher David S.
Принадлежит:

Provided is a compression resistant implant configured to fit at or near a bone defect to promote bone growth, the compression resistant implant comprising porous ceramic particles in a biodegradable polymer, and an oxysterol disposed in or on the compression resistant implant. Methods of making and use are further provided. 1. A compression resistant implant configured to fit at or near a bone defect to promote bone growth , the compression resistant implant comprising porous ceramic particles in an amount of about 30 wt % to about 99.5 wt % in a biodegradable polymer in an amount of about 0.1 wt % to about 20 wt % based on a total weight of the implant , and an oxysterol disposed in or on the compression resistant implant.2. An implant according to claim 1 , wherein the implant is not compressed any more than about 20% in any one direction for a period of at least about 30 days in vivo.3. An implant according to claim 1 , wherein (i) the porous ceramic particles are uniformly distributed throughout the implant; (ii) the oxysterol is uniformly distributed throughout the biodegradable polymer; and/or (iii) the oxysterol is uniformly distributed throughout the porous ceramic particles.4. An implant according to claim 1 , wherein the porous ceramic particles form a ceramic skeleton claim 1 , the skeleton having pores in the range of 1-10 mm in diameter claim 1 , and a total porosity of 50-98%.5. An implant according to claim 1 , wherein the implant comprises autograft claim 1 , allograft and/or xenograft bone particles.6. An implant according to claim 1 , wherein the biodegradable polymer comprises porcine-derived collagen claim 1 , human-derived collagen claim 1 , bovine-derived collagen claim 1 , piscine-derived collagen claim 1 , ovine-derived collagen claim 1 , recombinant collagen claim 1 , gelatin claim 1 , or combinations thereof.7. An implant according to claim 1 , wherein (i) the porous ceramic particles comprise bone powder claim 1 , demineralized bone ...

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Номер записи: 81
12-01-2017 дата публикации

Expandable interbody spacer

Номер: US20170007422A1
Автор: Bria Howell, Brian GARVEY, Chad Glerum, Christopher Saville, Conor Flaming, Daniel Waite, Edward Dwyer, James Himmelberger, Jason Gray, Jonathan Perloff, Kevin Gahman, Marcin Niemiec, Mark Weiman, Samuel Petersheim, Victoria Alexander, Vipin Kunjachan, William Rhoda
Принадлежит: Globus Medical Inc

Devices and methods for treating one or more damaged, diseased, or traumatized portions of the spine, including intervertebral discs, to reduce or eliminate associated back pain. In one or more embodiments, the present invention relates to an expandable interbody spacer. The expandable interbody spacer may comprise a first jointed arm comprising a plurality of links pivotally coupled end to end. The expandable interbody spacer further may comprise a second jointed arm comprising a plurality of links pivotally coupled end to end. The first jointed arm and the second jointed arm may be interconnected at a proximal end of the expandable interbody spacer. The first jointed arm and the second jointed arm may be interconnected at a distal end of the expandable interbody spacer.

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Номер записи: 82
12-01-2017 дата публикации

BONE GRAFTS AND METHODS OF MAKING AND USING BONE GRAFTS

Номер: US20170007740A1
Автор: Adams Allison, Adams Mark, Bhat Archana, Ortiz Ophir
Принадлежит:

Provided herein are bone grafts and methods of making and using the same, as well as products and kits that include such bone grafts. In particular, bone grafts are provided that include collagen Type I and one or more different types of mineral compositions having different dissolution properties and/or sizes, to enhance bone regeneration throughout the bone healing phase. 1. A bone graft comprising:20% to 95% by weight of collagen type I with respect to a total weight of the bone graft, and20% to 95% by weight of one or more minerals with respect to the total weight of the bone graft, wherein the one or more minerals have two or more dissolution rates, thereby allowing the bone graft to enhance bone healing in both early and late phases of bone healing.2. The bone graft of claim 1 , further comprising 0.2 to 20% by weight of hyaluronic acid with respect to the total weight of the bone graft.3. The bone graft of claim 1 , further comprising 0.1 to 20% by weight of acid or base with respect to the total weight of the bone graft.4. The bone graft of claim 1 , further comprising 20% to 95% by weight DBM with respect to the total weight of the bone graft.5. The bone graft of claim 1 , wherein the collagen type I is from a bovine or porcine source and is obtained from either skin (dermal) or tendon.6. The bone graft of claim 1 , wherein the one or more minerals comprise beta-tricalcium phosphate.7. The bone graft of claim 1 , wherein the one or more minerals comprise carbonate apatite.8. The bone graft of claim 1 , wherein the one or more minerals comprise calcium carbonate.9. The bone graft of claim 1 , wherein the one or more minerals have a size ranging from about 75 nm to 500 μm.10. The bone graft of claim 1 , wherein the one or more minerals include a first mineral having a first dissolution profile and a second mineral having a second dissolution profile claim 1 , wherein the first dissolution profile is different from the second dissolution profile in order to ...

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Номер записи: 83
11-01-2018 дата публикации

CERVICAL SPINOUS PROCESS STAPLE

Номер: US20180008320A1
Автор: MOSKOWITZ Ahmnon D., MOSKOWITZ Mosheh T., MOSKOWITZ Nathan C.
Принадлежит:

Thoracic/lumbar and cervical spinous process staples which staple/fuse adjacent spinous processes are disclosed. Thoracic/lumbar transverse process staples which staple/fuse adjacent transverse processes are also disclosed. Each embodiment has upper and lower claws connected by a ratchet spring mechanism, along with a multiplicity of bone fastener prongs attached to the upper and lower claws. Two sets of prongs on each staple claw are spaced by a distance approximately equal to the distance separating adjacent spinous or transverse processes so as to facilitate stapling/fusion of two adjacent processes. Also disclosed are staple prongs with multiple perforations which enable incorporation of bone fusion material thereby facilitating stapling/fusion of spinal elements. 1. (canceled)2. A spinous process fixation device comprising:a first elongate clamping structure extending from a first end to a second end and having a first spinous process engagement surface between the first end and the second end with a first set of bone fastener prongs extending from the first spinous process engagement surface proximate the first end and a second set of bone fastener prongs extending from the first spinous process engagement surface proximate the second end, wherein the first set of bone fastener prongs is separated from the second set of bone fastener prongs by a first portion of the first spinous process engagement surface that does not include bone fastener prongs;a second elongate clamping structure extending from a third end to a fourth end and having a second spinous process engagement surface between the third end and the fourth end with a third set of bone fastener prongs extending from the second spinous process engagement surface proximate the third end and a fourth set of bone fastener prongs extending from the second spinous process engagement surface proximate the fourth end, wherein the third set of bone fastener prongs is separated from the fourth set of bone ...

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Номер записи: 84
14-01-2021 дата публикации

Graft preparation station for repairing bone defects

Номер: US20210007863A1
Автор: Alexander Emmanuel Rodriguez, John David Paterson, Tyler Clevett
Принадлежит: Arthrex Inc

This disclosure relates to a graft preparation station and methods for repairing bone defects. The station described herein may be utilized for dimensioning a graft prior to positioning the shaped graft at a surgical site.

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Номер записи: 85
11-01-2018 дата публикации

Anterior-to-posterior uncinate joint stabilizer systems

Номер: US20180008427A1
Автор: Jeffrey John Larson, Theodore P. Bertele
Принадлежит: Uncinate Joint LLC

A system for stabilizing a cervical spine segment includes a pair of uncinate joint stabilizers for stabilizing a respective pair of uncinate joints. Each uncinate joint stabilizer is elongated along a lengthwise dimension and is configured for placement in the respective uncinate joint with the lengthwise dimension substantially oriented along an anterior-to-posterior direction of the cervical spine segment. Each uncinate joint stabilizer has height configured to define spacing of the respective uncinate joint. Each uncinate joint stabilizer includes a generally cylindrical portion with cylinder axis in the lengthwise dimension. The generally cylindrical portion has threads for threading the uncinate joint stabilizer into the respective uncinate joint along the anterior-to-posterior direction. The threads are interrupted by one or more fenestrations configured to accommodate bone graft material, bone growth, and/or tissue displaced from the respective uncinate joint by the uncinate joint stabilizer.

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Номер записи: 86
11-01-2018 дата публикации

Transforaminal intersomatic cage for an intervertebral fusion graft and an instrument for implanting the cage

Номер: US20180008430A1
Автор: Davis Reginald James, Hoffman Greg, Huppert Jean, Kaufman Kevin, McGee Alan, Mousselard Hugues, Rillardon Ludovic
Принадлежит:

This disclosure presents various embodiments of a transforaminal intersomatic cage for an intervertebral fusion graft, and an instrument and method for implanting the cage, an embodiment of the cage having a body in the shape of a circular arc and comprising a lateral concave surface, a lateral convex surface, a straight upper surface, a straight lower surface and an end wall having at least one hole, called the end hole, designed to receive a rod of an instrument for implanting the cage between the vertebrae, wherein: the end hole has an orientation that is more or less tangential to the circular arc described by the body; the extremity opposite to the end wall of the body includes a return part extending the body toward the center of the circle on which the circular arc described by the body lies. 121-. (canceled)22. An instrument for the implantation of an intersomatic cage for an intervertebral fusion graft comprising a body generally defining an arc , the body comprising a lateral concave surface; a lateral convex surface; a substantially transverse upper surface; a substantially transverse lower surface; an end wall at a first longitudinal extremity of the body , the end wall comprising an end hole oriented substantially tangential to the arc defined by the body; said instrument comprising:a rod comprising a retaining end configured for insertion in the end hole; a support spatula comprising a base and generally defining an arc complementary to the arc defined by the body,', 'a guide tube in which the rod is slidably disposed and to which the base of the support spatula is mounted, the guide tube comprising an opening through which the retaining end of the rod can transit for insertion in the end hole; and, 'a gripping end for gripping the intersomatic cage, the gripping end comprising'}a handling end for manipulating the instrument.23. An instrument according to claim 22 , wherein the rod extends substantially to the vicinity of the handling end of the ...

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Номер записи: 87
11-01-2018 дата публикации

Devices for Insertion into a Vertebral Body and Methods of Treating a Vertebral Body

Номер: US20180008432A1
Автор: Laurent Schaller
Принадлежит: Benvenue Medical Inc

Spinal tissue distraction devices that include a member which has a pre-deployed configuration for insertion between tissue layers and a deployed configuration in which the member, by change of configuration, forms a support structure for separating and supporting layers of spinal tissue.

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Номер записи: 88
11-01-2018 дата публикации

METHOD FOR RESTORING BONE USING SHAPEABLE BONE GRAFT SUBSTITUTE AND INSTRUMENTS FOR DELIVERY THEREOF

Номер: US20180008746A1
Автор: Bagga Charanpreet S., Clineff Theodore D., Erbe Erik M., Koblish Antony, Nagvajara Gina M., Paris Michael W.
Принадлежит:

Disclosed is directed to a method for restoring bone in an animal comprising: accessing a site to be restored; loading a syringe body with a flowable bone graft material; mating the syringe body with a delivery tube; positioning the delivery tube at the site to be restored; using a syringe piston to advance the said material into the delivery tube; using the syringe piston or a plunger that mates with the delivery tube after removal of the syringe body to deliver the bone graft to the site at a force of less than 50 lbs. extrusion force; wherein said material is at least 75% porous with a mineral to polymer ratio of 80:20. 1. A method for restoring bone in an animal comprising:accessing a site to be restored;loading a syringe body with a flowable bone graft material;mating the syringe body with a delivery tube;positioning the delivery tube at the site to be restored;using a syringe piston to advance the said material into the delivery tube;using the syringe piston or a plunger that mates with the delivery tube after removal of the syringe body to deliver the bone graft to the site at a force of less than 50 lbs. extrusion force;wherein said material is at least 75% porous with a mineral to polymer ratio of 80:20.2. The method of claim 1 , wherein the extrusion force is between about 20 lbs to about 25 lbs.3. The method of claim 1 , wherein the mineral is calcium phosphate.4. The method of claim 1 , wherein the polymer is collagen.5. The method of claim 1 , wherein the syringe body and delivery tube are threadingly engaged.6. The method of claim 1 , wherein said graft material is 80% porous.7. The method of claim 1 , wherein said graft material is 90% porous. The present application is a continuation of U.S. application Ser. No. 14/933,217, filed on Nov. 5, 2015, which is a divisional of U.S. patent application Ser. No. 10/874,994, filed on Jun. 23, 2004, the disclosures of which are incorporated herein by reference.This invention relates to porous, shapeable ...

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Номер записи: 89
09-01-2020 дата публикации

Intervertebral fusion device comprising an intervertebral stabilising screw and a composition for bone remodelling

Номер: US20200008944A1
Автор: Christian Rudolf Morgenstern De Muller, Rudolf Morgenstern Lopez
Принадлежит: Endospine SL

The invention relates to an intervertebral fusion device comprising an intervertebral stabilizing screw and a composition for bone remodeling. The intervertebral stabilizing screw comprises: a main body with an axial through-hole and a distal thread that is secured to the bone, located at a distal end of the main body; a hollow proximal secondary body that can slide along the length of the main body; and a travel stop for the proximal secondary body, located on an outer surface of the main body. According to the invention, the proximal secondary body also includes an external thread for securing to the bone, and the main body comprises at least one fill hole, located between the distal thread and the travel stop, for connecting an intervertebral space to the aforementioned axial hole.

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Номер записи: 90
08-01-2015 дата публикации

Anterior Intervertebral Fusion with Fixation System, Device, and Method

Номер: US20150012102A1
Автор: Joshua Michael Aferzon
Принадлежит: Individual

A system, device, and method are disclosed for anterior intervertebral fusion with fixation. An intervertebral fusion with fixation device includes a spacer configured to fit into a disc space between plural vertebrae, the spacer including through holes between and through plural sidewalls. A first fixating element is rigidly preloaded in a first portion of the spacer along a first linear trajectory. A second fixating element is rigidly preloaded in a second portion of the spacer along a second linear trajectory. An integrated drill and screwdriver instrument is adapted to extend through a cannula of the first fixating element and second fixating element and penetrate the vertebra. The instrument is further adapted to drive the head of the first fixating element and second fixating element into the vertebra and lock the first fixating element and second fixating element with respect to the spacer to prevent extrusion from the spacer.

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Номер записи: 91
08-01-2015 дата публикации

NOVEL BIOLOGICAL IMPLANT COMPOSITIONS, IMPLANTS AND METHODS

Номер: US20150012107A1
Автор: Hilliard Randall Keith, Koford Keith Cameron, Long Nathaniel Scott, Scharringhausen Erica Lee
Принадлежит:

The present application is directed to the field of implants comprising processed hard or soft biological tissues for use in implantation in humans. The molded biological tissue implants of the present application are preferably made from allograft soft tissue sources and demineralized bone matrix. The present application provides biological implants exhibiting advantageous properties of absorption, expansion, resiliency and shape retention. The properties of the biological implants produced by the methods of the present application are leveraged in the creation and development of novel biological implant constructs and of novel methods of treatment and surgical technique. 1. A biological graft comprising;a bone block of cortical bone, cancellous bone or both, said bone block having at least one porous or semi-porous surface; anda molded tissue component comprising demineralized bone matrix (DBM) and a tissue slurry;wherein said molded tissue component is integrated into said porous or semi-porous surface of said bone block.2. The graft of claim 1 , wherein said molded tissue component is frozen and lyophilized along at least a portion of at least one outer surface of said bone block.3. The graft of claim 1 , wherein said bone block further comprises at least one slot claim 1 , groove or hole to increase penetration of said molded tissue component.4. The graft of claim 1 , wherein said molded tissue component covers at least two sides of said bone block and substantially fills a passageway between at least two of said at least two sides.5. The graft of claim 1 , wherein said bone block is in the shape of a wedge claim 1 , trapezoid claim 1 , plank or ring.6. The graft of consisting essentially of human tissue components.7. The graft of comprising xenograft tissue components.8. The graft of claim 1 , wherein said molded tissue component comprises least one layer which is osteoconductive claim 1 , compressible claim 1 , conformable claim 1 , and hydratable.9. The ...

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Номер записи: 92
19-01-2017 дата публикации

STANDALONE INTERBODY IMPLANTS

Номер: US20170014241A1
Автор: Gray Jason, Hansell Noah, Hunt Michael, Klimek Jennifer, Martynova Veronika, Padovani Nick, Paul David, Zappacosta Jason
Принадлежит:

Stand-alone interbody fusion devices for engagement between adjacent vertebrae. The stand-alone interbody fusion devices may include frames and one or more endplates coupled to the frame. The frame may be configured and designed to provide the apertures which are designed to retain bone fasteners, such as screws or anchors, and secure the implant to the adjacent vertebrae. 1. An intervertebral implant for implantation in an intervertebral space between adjacent vertebrae , the implant comprising:a frame comprising a body, a first extension extending from the body, and a second extension extending from the body, wherein the frame further comprises a first hole for receiving a first screw and a second hole for receiving a second screw;a first screw extending through the first hole;a second screw extending through the second hole; anda spacer connected to the frame, wherein the spacer comprises a first spacer portion, a second spacer portion, and a connector between the first spacer portion and the second spacer portion, wherein the connector separates the first spacer portion and the second spacer portion such that they are not in direct contact with one another.2. The implant of claim 1 , wherein the frame further comprises an upper surface and a lower surface claim 1 , wherein a first torsional stabilizer extends from the upper surface and a second torsional stabilizer extends from the lower surface.3. The implant of claim 1 , wherein the frame further comprises a first eyebrow that forms the first hole and a second eyebrow that forms the second hole.4. The implant of claim 1 , wherein the first screw is angled in an upward direction and the second screw is angled in a downward direction.5. The implant of claim 1 , wherein the connector comprises a cross-shaped member.6. The implant of claim 1 , wherein the connector comprises a first tenon and a second tenon.7. The implant of claim 6 , wherein the first spacer portion comprises a first mortise for receiving the ...

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Номер записи: 93
19-01-2017 дата публикации

Platelet-Derived Growth Factor Compositions and Methods of Use Thereof

Номер: US20170014545A1
Автор: Samuel E. Lynch
Принадлежит: Biomimetic Therapeutics LLC

A method for promoting growth of bone, periodontium, ligament, or cartilage in a mammal by applying to the bone, periodontium, ligament, or cartilage a composition comprising platelet-derived growth factor at a concentration in the range of about 0.1 mg/mL to about 1.0 mg/mL in a pharmaceutically acceptable liquid carrier and a pharmaceutically-acceptable solid carrier.

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Номер записи: 94
19-01-2017 дата публикации

OSTEOGENIC REGENERATIVE SCAFFOLD MATRIX COMPOSITION

Номер: US20170014550A1
Автор: Elazizi Mohamad, Murray Peter, Temple H. Thomas
Принадлежит: NOVA SOUTHEASTERN UNIVERSITY

The implantable scaffold matrix composition for osteogenic regeneration has a biodegradable polymer material selected from the group consisting of one or more of polylactic acid, polyglycolic acid, or polycaprolactone, or any combination thereof to provide a time release delivery of an osteogenic effect and further has a pharmaceutical composition selected from the group consisting of one or more of ibuprofen, non-steroidal anti-inflammatory drugs (NSAIDS), acetaminophen, or naproxen sodium or any combination thereof and wherein the implantable composition has a primary and a secondary time release. The primary time release being one of the polymer compositions; each time release extending occurring between 0 days and 19 days, both not being at 0 days. In a preferred composition, the scaffold has an organic material for inhibiting osteoclast selected from a group consisting of one or more of Galardin, Decorin, Actinonin, Marimastat, Batimastat, and phosphodiesterase type 4 or any combination of osteoclast inhibitors. 1. An implantable scaffold matrix composition for osteogenic regeneration , the scaffold comprises:a biodegradable polymer material to promote osteoblast attachment;a pharmaceutical composition to control local inflammation; andan organic material for inhibiting the osteoclast resorption of bone.2. The implantable scaffold matrix composition for osteogenic regeneration claim 1 , the scaffold of claim 1 , wherein the polymer material is material selected from the group consisting of one or more of polylactic acid claim 1 , polyglycolic acid claim 1 , or polycaprolactone claim 1 , or any combination thereof.3. The implantable scaffold matrix composition for osteogenic regeneration claim 1 , the pharmaceutical composition of wherein the local inflammation is controlled by drugs consisting of one or more of ibuprofen claim 1 , non-steroidal anti-inflammatory drugs (NSAIDS) claim 1 , acetaminophen claim 1 , or naproxen sodium or any combination thereof.4. ...

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Номер записи: 95
18-01-2018 дата публикации

BONE FUSION SYSTEM

Номер: US20180014866A1
Автор: Aghayev Kamran, Doulgeris James J., Gonzalez Blohm Sabrina A, Vrionis Frank D.
Принадлежит:

A method and system for performing bone fusion and/or securing one or more bones, such as adjacent vertebra, are disclosed. The screws include a threaded tip connected to a main shaft and a threaded outer sleeve that rotates relative to the outer shaft until locked down. Independent rotation of the threaded outer sleeve relative to the threaded distal tip allows compression or distraction to modify the gap between the vertebral bodies. The screws are passed from the inferior to superior vertebra or superior to inferior, for example, through a trans-pedicular route to avoid neurological compromise. At the same time, the path of screw insertion is oriented to reach superior or inferior vertebra. An intervertebral cage of the system is configured for lateral expansion from a nearly straight configuration to form a large footprint in the disc space. The screws and cage may be combined for improved fixation with minimal invasiveness. 1. A bone screw comprising:a threaded tip;a main shaft having a proximal end and a distal end, the distal end of the main shaft connected to the threaded tip and extending proximally therefrom;a threaded outer sleeve having a proximal end, a distal end, and an interior surface defining an axial opening extending between the proximal end and distal end and having a proximal portion and a distal portion, wherein at least the distal portion of the interior surface is non-threaded, the axial opening has a diameter greater than the proximal end of the main shaft, and the threaded outer sleeve is extendable over and freely rotatable about the proximal end of the main shaft, anda stop member coupled to the main shaft proximal to and axially spaced apart from a proximal end of the threaded tip, the stop member abutting the threaded outer sleeve during rotation of the threaded outer sleeve to stop axial translation of the outer threaded sleeve relative to the threaded tip.2. The screw of claim 1 , wherein the proximal end of the main shaft has a ...

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Номер записи: 96
18-01-2018 дата публикации

SUBCHONDRAL TREATMENT OF JOINT PAIN OF THE SPINE

Номер: US20180014943A1
Автор: Leinberry Charles F., Mathews Hallett, NICHOLS David L., Sharkey Peter F., Viscogliosi Marc R.
Принадлежит:

Methods for altering the natural history of degenerative disc disease and osteoarthritis of the spine are proposed. The methods focus on the prevention, or delayed onset or progression of, subchondral defects such as bone marrow edema or bone marrow lesion, and subchondral treatment to prevent the progression of osteoarthritis or degenerative disc disease in the spine and thereby treat pain. 1. (canceled)2. A method of injecting an injectable fluid material into a targeted treatment area in a subchondral region of a facet in a spinal segment of a patient , the method comprising:identifying bone marrow edema in a facet in a spinal segment of a patient, the bone marrow edema occurring in a subchondral region of the facet, the subchondral region of the facet occurring under an articular surface of the facet;creating, in the facet that contains the bone marrow lesion in the subchondral region, a subchondral injection path to a targeted treatment area for injecting an injectable fluid material into the targeted treatment area, wherein the targeted treatment area includes an area in the subchondral region where the bone marrow edema was identified, and wherein said creating preserves an existing condition of the articular surface of the facet; andinjecting an injectable fluid material into the targeted treatment area via the subchondral injection path, wherein the injectable fluid material includes an osteogenic, osteoconductive and/or osteoinductive material.3. The method of claim 2 , wherein said identifying includes identifying with MRI.4. The method of claim 2 , wherein the injectable fluid material is left in the targeted treatment area without also delivering and leaving a solid structural implant in the targeted treatment area in addition to the injectable fluid material.5. The method of claim 2 , wherein said creating is conducted without further creating a void inside the facet in or adjacent to the targeted treatment area.6. The method of claim 2 , wherein the ...

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Номер записи: 97
18-01-2018 дата публикации

BI-DIRECTIONAL FIXATING/LOCKING TRANSVERTEBRAL BODY SCREW/INTERVERTEBRAL CAGE STAND-ALONE CONSTRUCTS

Номер: US20180014945A1
Автор: ALVARADO Pablo A. Valdivia Y., MOSKOWITZ Ahmnon D., Moskowitz Mosheh, MOSKOWITZ Nathan C.
Принадлежит:

A bi-directional fixating transvertebral (BDFT) screw/cage apparatus is provided. The BDFT apparatus includes an intervertebral cage including a plurality of internal angled screw guides, a plurality of screw members, and a cage indentation adjacent to the screw guides that independently or supplemented by other screw locking mechanisms prevents the screw members from pulling out of the internal angled screw guides. The internal angled screw guides orient a first screw member superiorly and a second screw member inferiorly. The intervertebral cage is adapted for posterior lumbar intervertebral placement, anterior lumbar intervertebral placement, anterio-lateral thoracic intervertebral placement, or anterior cervical intervertebral placement. 187-. (canceled)88. An intervertebral combination internal screw guide and fixation apparatus configured to be inserted into a disc space between a first vertebral body and a second vertebral body and to provide fusion of the first vertebral body to the second vertebral body via biological bone fusion and screw fusion , the apparatus comprising: an open space between the top, bottom, first, and second sidewalls capable of receiving bone filling for biological bone fusion,', 'a first slot on a first outer side of the first sidewall,', 'a second slot on a second outer side of the second sidewall of the two sidewalls, wherein the second slot is positioned opposite of the first slot, wherein the first slot is positioned along a first centerline axis that bisects the first side wall and wherein the second slot is positioned along a second centerline axis that bisects the second side wall,', 'a first internal screw guide having a first entry opening and a first exit opening, the first entry opening of the first internal screw guide formed at least partially in a top surface of the top wall and the first exit opening formed at least partially in a bottom surface of the top wall and at least partially in a first side surface of the top ...

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Номер записи: 98
17-01-2019 дата публикации

Arcuate Fixation Member

Номер: US20190015219A1
Автор: Donner Thomas, EVANS David E., Laurence Lawton, Miller William, Schmura Kurt, Schoenly Jared, Singhatat Wamis
Принадлежит:

Arcuate fixation members with varying configurations and/or features are provided, along with additional components for use therewith in provided fixation systems and intervertebral implant systems. The arcuate fixation members may be of varying lengths, cross sectional geometries, and/or cross sectional areas, and may be configured with various features such as heads configured to accept other fixation system components, tabs to allow arcuate fixation member-in-arcuate fixation member or fixation anchor-in-arcuate fixation member configurations. Applications of fixation systems and intervertebral implants systems utilizing arcuate fixation members are particularly suitable when a linear line-of-approach for delivering fixation members is undesirable. 1an implant body defining a first bone-engaging surface, a second bone-engaging surface spaced from the first bone engaging surface along a transverse direction, a posterior end, an anterior end spaced from the posterior end along a longitudinal direction that is perpendicular to the transverse direction, and opposed lateral sides spaced apart with respect to each other along a lateral direction that is substantially perpendicular to the transverse direction and the longitudinal direction, the opposed lateral sides extending between the first and second bone-engaging surfaces;a fixation plate attached to the implant body, the fixation plate defining a posterior surface and an anterior surface spaced from the posterior surface along the longitudinal direction, and first and second lateral arms that extend away from the anterior surface along the longitudinal direction, the first and second lateral arms each defining a terminal end attached to the implant body, the fixation plate further defining a first and second upper curved apertures, and first and second lower curved apertures spaced from the first and second upper curved apertures along the transverse direction, and each at least one curved aperture having an ...

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Номер записи: 99
21-01-2021 дата публикации

METHOD FOR TREATING JOINT PAIN

Номер: US20210015618A1
Автор: Baumgartl William, Borbolla Jack, Chavez Fernando, II Charles, Puhl, Reeves Dane
Принадлежит:

A method for treating joint pain in a subject is disclosed. The method can include inserting a bone dowel and a first portion of a bone marrow aspirate into a subchondral region of a bone that is part of a joint being treated and introducing a second portion of the bone marrow aspirate into the intraarticular space of the joint being treated. 1. A method for treating joint pain in a subject , the method comprising:(a) inserting a bone dowel and a first portion of a bone marrow aspirate into a subchondral region of a bone that is part of a joint being treated; and(b) introducing a second portion of the bone marrow aspirate into the intraarticular space of the joint being treated.2. The method of claim 1 , further comprising harvesting the bone dowel from the subject.3. The method of claim 2 , wherein the bone dowel is harvested from an iliac crest claim 2 , vertebra claim 2 , calcaneus claim 2 , or tibia of the subject.4. The method of claim 3 , further comprising harvesting bone marrow aspirate from the subject.5. The method of claim 4 , wherein the bone marrow aspirate is harvested from the site claim 4 , or adjacent to the site claim 4 , where the bone dowel is harvested.6. The method of claim 5 , wherein the bone marrow aspirate is harvested via a jamshidi needle.7. The method of claim 1 , wherein insertion of the bone dowel and the first portion of bone marrow aspirate claim 1 , and intraarticular injection of the second portion of bone marrow aspirate are performed within 5 minutes to 6 hours of each other claim 1 , preferably within 5 minutes to 4 hours of each other claim 1 , or more preferably within 5 minutes to 2 hours of each other.8. The method of claim 1 , wherein the first portion of bone marrow aspirate is treated to initiate coagulation.9. The method of claim 1 , wherein the joint is a knee joint claim 1 , shoulder joint claim 1 , ankle joint or hip joint.10. The method of claim 1 , wherein the subchondral region is a subchondral edema or subchondral ...

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Номер записи: 100