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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 4527. Отображено 197.
30-08-2018 дата публикации

Номер: RU2016133688A3
Автор:
Принадлежит:

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27-11-2016 дата публикации

СИРОП ЛАПЧАТКИ БЕЛОЙ

Номер: RU2603466C1

Изобретение относится к химико-фармацевтической промышленности, в частности к сиропу лапчатки белой (Potentilla alba L., сем. Розоцветные - Rosaceae), обладающему антибактериальным действием. Сироп лапчатки белой, обладающий антибактериальным действием, который изготавливают на основе сорбита и водного извлечения, получаемого из корневищ и корней лапчатки белой, при определенных условиях. Вышеописанный сироп обладает эффективным антибактериальным действием, является стабильным. 1 пр., 1 ил.

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15-04-2020 дата публикации

Beet juice having increased intestinal absorption rate, preparation method therefor and use thereof

Номер: GB0002578035A
Автор: DAISIK HARM, Daisik Harm
Принадлежит:

The present invention relates to beet juice having an increased intestinal absorption rate, a preparation therefor and a use thereof and, more specifically, to: beet juice, which has an enhanced intestinal digestion and absorption rate through the conversion of high-molecular compounds into low-molecular compounds by means of low-temperature maturation of beets, has a grassy smell removed therefrom through the roasting of beets, and has a reduced grassy taste and bitterness by being mixed with carrot juice and apple juice; and an antioxidant or antihypertensive health food composition using the beet juice.

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22-11-2017 дата публикации

Ozonation of cannabinoids

Номер: GB0201716491D0
Автор:
Принадлежит:

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31-01-2017 дата публикации

COIX SEED OIL COMPRISING 11 TRIGLYCERIDES, FORMULATION AND APPLICATION THEREOF

Номер: AP2017009707A0
Автор: LI DAPENG
Принадлежит:

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31-01-2017 дата публикации

COIX SEED OIL COMPRISING 16 GLYCERIDES, FORMULATION AND APPLICATION THEREOF

Номер: AP2017009709A0
Автор: LI DAPENG
Принадлежит:

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31-01-2017 дата публикации

COIX SEED OIL COMPRISING 16 GLYCERIDES, FORMULATION AND APPLICATION THEREOF

Номер: AP0201709709D0
Автор: LI DAPENG
Принадлежит:

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31-01-2017 дата публикации

COIX SEED OIL COMPRISING 11 TRIGLYCERIDES, FORMULATION AND APPLICATION THEREOF

Номер: AP0201709707D0
Автор: LI DAPENG
Принадлежит:

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31-01-2017 дата публикации

COIX SEED OIL COMPRISING 11 TRIGLYCERIDES, FORMULATION AND APPLICATION THEREOF

Номер: AP0201709707A0
Автор: LI DAPENG
Принадлежит:

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31-01-2017 дата публикации

COIX SEED OIL COMPRISING 16 GLYCERIDES, FORMULATION AND APPLICATION THEREOF

Номер: AP0201709709A0
Автор: LI DAPENG
Принадлежит:

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03-06-2021 дата публикации

Cannabis plants with a cannabinoid profile enriched for cannabidiol and Δ-9-tetrahydrocannabinol

Номер: AU2019374165A1
Принадлежит:

The present disclosure relates generally to new cannabis plants, including parts, extracts and uses thereof, comprising a cannabinoid profile enriched for total CBD (i.e., cannabidiol (CBD) and cannabidiolic acid (CBDA)) and for total THC (i.e., Δ-9-tetrahydrocannabinol (THC) and Δ-9-tetrahydrocannabinolic acid (THCA)).

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03-06-2021 дата публикации

Cannabis plants with a cannabinoid profile enriched for Δ-9-tetrahydrocannabinol and cannabigerol

Номер: AU2019376697A1
Принадлежит:

The present disclosure relates to new cannabis plants, including parts, extracts and uses thereof, comprising a cannabinoid profile enriched for total THC (i.e., Δ-9-tetrahydrocannabinol (THC) and Δ-9-tetrahydrocannabinolic acid (THCA)) and total CBG (i.e., cannabigerol (CBG) and cannabigerolic acid (CBGA)).

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25-05-2017 дата публикации

Hydroxymethylfurfural derivative

Номер: AU2012354703B2
Принадлежит: FB Rice

A hydroxymethylfurfural derivative represented by general formula (A). In the formula, R is selected from the group consisting of formula (I), (II) HOOCCH ...

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01-12-2016 дата публикации

Pharmaceutical composition for preventing and treating senile dementia and preparation method therefor

Номер: AU2015276657A1
Принадлежит: Baldwins Intellectual Property

A pharmaceutical composition for preventing and treating senile dementia and a preparation method therefor. The active ingredients of the pharmaceutical composition are prepared from the following raw materials in weight part: 20 to 50 parts of epimedium and 15 to 55 parts of tuckahoe; or 20 to 50 parts of epimedium, 15 to 55 parts of tuckahoe and 10 to 55 parts of acanthopanax; or 20 to 50 parts of epimedium, 15 to 50 parts of tuckahoe, 15 to 50 parts of acanthopanax, and 6 to 15 parts of rhizoma anemarrhenae.

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09-01-1997 дата публикации

Novel extracts of cucurbita sp., process for their preparation and use in medicaments and in cosmetics

Номер: AU0000674710B2
Принадлежит:

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10-05-2019 дата публикации

CLOSED-LOOP MULTI-STAGE CHILLED FILTER SYSTEM

Номер: CA0003023563A1
Принадлежит: LOVELAND, DAMIEN G.

A series of vertically oriented filters of decreasing pore size is sealed from the atmosphere. Pressurized gas is used to force the liquid to be filtered through the filters. The filter stages are thermally insulated from ambient temperatures in order to maintain the liquid passing through at a reduced temperature. Each filter stage has a removable lid, which provides convenient access for replacing the filter cartridge, allowing it to be changed without disturbing the thermally insulated sidewalls of the filter stage.

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10-10-2019 дата публикации

PLANT-BASED NERIUM OLEANDER EXTRACTS AND METHODS

Номер: CA0003094126A1
Принадлежит: SMART & BIGGAR LLP

Methods of extracting Nerium oleander plant species with a plant juice or plant oil are disclosed. Pharmaceutical and cosmetic compositions comprising the resulting Nerium oleander extracts and methods of using them are also disclosed.

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02-07-2015 дата публикации

TREATMENT OF PAIN

Номер: CA0002935204A1
Принадлежит:

The invention relates to a method of treating or preventing pain, or a condition associated with pain, in a subject in need thereof, comprising applying topically an effective amount of an extract of Zingiber Officinale (ginger), and to topical compositions and articles of manufacture comprising an extract of Zingiber Officinale.

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23-12-2015 дата публикации

PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING SENILE DEMENTIA AND PREPARATION METHOD THEREOF

Номер: CA0002950638A1
Принадлежит:

A pharmaceutical composition for preventing and treating senile dementia and a preparation method therefor. The active ingredients of the pharmaceutical composition are prepared from the following raw materials in weight part: 20 to 50 parts of epimedium and 15 to 55 parts of tuckahoe; or 20 to 50 parts of epimedium, 15 to 55 parts of tuckahoe and 10 to 55 parts of acanthopanax; or 20 to 50 parts of epimedium, 15 to 50 parts of tuckahoe, 15 to 50 parts of acanthopanax, and 6 to 15 parts of rhizoma anemarrhenae.

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21-01-2016 дата публикации

COIX SEED OIL COMPRISING 11 TRIGLYCERIDES, FORMULATION AND APPLICATION THEREOF

Номер: CA0002954796A1
Автор: LI, DAPENG, LI DAPENG
Принадлежит:

A coix seed oil comprising 13 triglycerides extracted from coix seeds, formulation and application thereof. Specifically, the coix seed oil comprises the following 11 triglyceride components (calculated by mass percentage): glyceryl trilinoleate (4.87-6.99%), glyceryl 1-oleate-2,3-dilinoleate (13.00-18.69%), glyceryl 1-palmitate-2,3-dilinoleate (5.25-7.54%), glyceryl1,3-dioleate-2-linoleate (13.23-19.02%), glyceryl 1-palmitate-2-linoleate-3-oleate (10.26-14.75%), glyceryl 1,3-dipalmitate-2-linoleate (2.28-3.28%), glyceryl trioleate (14.44-20.76%), glyceryl 1-palmitate-2,3-dioleate (8.06-11.58%), glyceryl 1-oleate-2-linoleate-3-stearate (1.37-1.97%), glyceryl 1,3-dipalmitate-2-oleate (1.52-2.19%), and 1,2-dioleate-3-stearate (1.29-1.86%). The coix seed oil can be used in the preparation of anti-tumour medicine.

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21-01-2016 дата публикации

COIX SEED OIL COMPRISING 16 GLYCERIDES, FORMULATION AND APPLICATION THEREOF

Номер: CA0002954797A1
Автор: LI, DAPENG, LI DAPENG
Принадлежит:

A coix seed oil comprising 16 glycerides extracted from coix seeds, formulation and application thereof. The coix seed oil comprises the following 5 diglyceride components and 11 triglyceride components (calculated by mass percentage): 1,3-dioleate diglyceride (0.40-0.58%), 1-linoleate-3-oleate diglyceride (0.91-1.31%), 1,2-dioleate diglyceride (0.24-0.35%), 1-oleate-2-linoleate diglyceride (0.66-0.95%), 1,2-linoleate diglyceride (0.33-0.47%), glyceryl trilinoleate (4.87-6.99%), glyceryl 1-oleate-2,3-dilinoleate (13.00-18.69%), glyceryl 1-palmitate-2,3-dilinoleate (5.25-7.54%), glyceryl1,3-dioleate-2-linoleate (13.23-19.02%), glyceryl 1-palmitate-2-linoleate-3-oleate (10.26-14.75%), glyceryl 1,3-dipalmitate-2-linoleate (2.28-3.28%), glyceryl trioleate (14.44-20.76%), glyceryl 1-palmitate-2,3-dioleate (8.06-11.58%), glyceryl 1-oleate-2-linoleate-3-stearate (1.37-1.97%), glyceryl 1,3-dipalmitate-2-oleate (1.52-2.19%), and 1,2-dioleate-3-stearate (1.29-1.86%). The coix seed oil can be used ...

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31-07-2017 дата публикации

SEEDS OIL S TEARS, CONTAINING 11 TRIGLYCERIDES, AND ITS PHARMACEUTICAL PREPARATION AND ITS APPLICATION

Номер: EA0201790119A1
Автор:
Принадлежит:

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16-10-2018 дата публикации

A traditional Chinese medicine composition used for treating ovarian cancer and a preparing method thereof

Номер: CN0108653686A
Автор: YUAN CUNZHONG
Принадлежит:

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18-12-2015 дата публикации

ESSENTIAL OIL OF ACHILLEE AS AN ANTI-AGING

Номер: FR0003012038B1
Принадлежит: L'OREAL

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02-06-2017 дата публикации

PRODUCTION METHOD OF ARONIA EXTRACT AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING PROSTATISM, COMPRISING ARONIA EXTRACT, AS ACTIVE INGREDIENT

Номер: KR1020170060737A
Принадлежит:

The present invention relates to a production method of an aronia extract, a pharmaceutical composition for preventing or treating prostatism, comprising an aronia extract, as an active ingredient, and a health functional food for preventing or alleviating prostatism and, more specifically, to a production method of an aronia extract, comprising the steps of: a) drying and crushing aronia; and b) supercritical extracting the crushed product of step a) by adding carbon dioxide and a co-solvent to the crushed product, to a pharmaceutical composition for preventing or treating prostatism, comprising an aronia extract, as an active ingredient produced by the method, and to a health functional food for preventing or alleviating prostatism. COPYRIGHT KIPO 2017 (AA) Supercritical extract (BB) Serenosa repens (50 μg/ml) (CC) Aronia melanocarpa (50 μg/ml) ...

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08-07-2020 дата публикации

A composition for improving, preventing and treating of asthmatic containing oriental medicine herbs oil extract as an active ingredient

Номер: KR1020200082648A
Автор:
Принадлежит:

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27-05-2015 дата публикации

COMPOSITION COMPRISING EUPATORIUM SPP. EXTRACT AS ACTIVE INGREDIENT FOR PREVENTING AND TREATING METABOLIC BONE DISEASE

Номер: KR1020150056752A
Принадлежит:

The present invention relates to a Eupatorium spp. extract having anti-obesity effects as a result of decreasing adipocytes and increasing osteoblasts, as well as the effects of preventing bone disease or fractures as a result of increasing osteoblasts and of preventing osteoporosis as a result of decreasing adipocytes and increasing osteoblasts by the same proportion in mesenchymal stem cells. Extract in Eupatorium spp. may inhibit the activity of PPARγ, AP2, CD36, adiponectin C/EBPα, and LPL, which serve as significant factors for adipocyte differentiation in C3H10T1/2 cells, which are pluripotent stem cell lines, and may increase the activity of ALP, osterix, CO1I and RUNX2, which serve as significant factors for osteoblast differentiation, thereby being used as a useful material for preventing and treating osteoporosis. COPYRIGHT KIPO 2015 (AA) Leaf (BB) Stem (CC) Flower (DD) Outpost ...

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10-02-2022 дата публикации

METHODS OF TREATING TUBEROUS SCLEROSIS COMPLEX WITH CANNABIDIOL AND EVEROLIMUS

Номер: US20220040155A1
Принадлежит: GW Research Ltd

The present disclosure provides methods of treating tuberous sclerosis complex comprising administering cannabidiol and everolimus.

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20-02-2020 дата публикации

ENZYME-ASSISTED SUPERCRITICAL EXTRACTION OF NIGELLA SATIVA SEEDS

Номер: US20200054704A1
Принадлежит:

The present invention relates to novel black cumin extract compositions and a green process for making the composition. The black cumin extract composition of the invention can be used to treat anxiety, sleep and stress disorders along with significant effect on memory enhancement. The composition is available in oil and powder forms. 1. A process for preparing a biologically active black cumin seed extract in free flowing powder form using black cumin seeds , comprising:(a) pre-treating powdered or flaked black cumin seeds with enzymes, followed by supercritical carbon dioxide extraction of the oil from the seeds to obtain a super critical extracted oil fraction which comprises non-volatile fixed oils rich in α-linoleic acid and volatile oils rich in thymoquinone;(b) extracting the residual black cumin seed material left after step (a) with a hydrophilic solvent to obtain residual black cumin seed extract;(c) spray-drying the residual black cumin seed extract from step (b) to obtain a residual black cumin seed free flowing powder;(d) dissolving the residual black cumin seed extract free flowing powder from step (c) in water to obtain a residual black cumin seed extract solution at 10 to 25% total dissolved solids level;(e) mixing the supercritical extracted oil fraction from step (a) with the residual black cumin seed solution obtained step (d), followed by homogenization or ultrasonication of the mixture thus obtained to produce an emulsion; and(f) spray-drying or freeze drying the emulsion from step (e) to obtain black cumin seed extracted oil composition in free flowing powder form;wherein the black cumin seed extracted oil composition in free flowing powder form comprises thymoquinone in the range of 0.1 to 8%.2. A process for preparing biologically active black cumin seed extract in liquid oil form using black cumin seeds , comprising:(a) pre-treating the powdered or flaked black cumin seeds with water to form a slurry and further treating the slurry with at ...

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10-09-2020 дата публикации

TERPENE ENRICHMENT METHODS AND SYSTEMS

Номер: US20200281995A1
Принадлежит:

The present disclosure provides methods and systems producing active extraction products from cannabis resin. An example method comprises introducing a mixture of a resin and an extractor into a sealed container, heating the mixture to extract cannabinoids and terpenes from the resin, adding water to the mixture, cooking the mixture and water, for example at high temperature and pressure for a predetermined time period to decarboxylate the cannabinoids, allowing the mixture and water to cool and separate, and removing an active extraction product from an upper portion of the sealed container.

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02-09-2021 дата публикации

METHODS OF TREATING TUBEROUS SCLEROSIS COMPLEX WITH CANNABIDIOL AND EVEROLIMUS

Номер: US20210267950A1
Принадлежит:

The present disclosure provides methods of treating tuberous sclerosis complex comprising administering cannabidiol and everolimus.

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02-01-2018 дата публикации

Composition for amelioration of peri- and post-menopausal symptoms and a process for producing the same

Номер: US0009855308B2

The present invention provides a nutraceutical composition, a process for the preparation of the nutraceutical composition useful for amelioration of peri- and post-menopausal symptoms in women. The nutraceutical composition is stable, directly compressible, water soluble, free flowing form having particle size not more than 2.0 μm comprising extract of Trigonella foenum-graecum, at least one bioavailable form of magnesium and vitamin E. The present invention also provides a method of treating ameliorating, treating and/or preventing peri- and post-menopausal discomforts in a subject suffering from peri- or post-menopausal symptoms comprising administering to the subject a therapeutically effective amount of the nutraceutical composition.

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28-03-2019 дата публикации

METHOD FOR CONDUCING CONCENTRATED CANNABIS OIL TO BE STABLE, EMULSIFIABLE AND FLAVORLESS FOR USE IN HOT BEVERAGES AND RESULTING POWDERIZED CANNABIS OIL

Номер: US2019090513A1
Принадлежит:

A method for producing powderized cannabis oil, and the resulting powderized cannabis oil, in which concentrated cannabis oil is mixed with and absorbed by a modified starch powder, preferably maltodextrin, in a ratio of at least three grams of starch powder for every one-eighth of a gram of cannabis oil is disclosed. Further disclosed are beverages, baked goods and single-serve beverage brewing cartridges utilizing or incorporating the powderized cannabis oil to create human-consumable products that contain an emulsified, tasteless, and odorless dose of cannabis oil.

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26-05-2022 дата публикации

METHODS FOR CONTINUOUS EXTRACTION AND PURIFICATION OF A UNIQUE FLAVAN-3-OL EXTRACT FROM IMMATURE WHOLE GRAPE CLUSTERS AND COMPOSITIONS THEREOF

Номер: US20220160810A1
Автор: James A. Kennedy
Принадлежит:

The present disclosure provides a novel process for the continuous extraction, purification and production of a flavan-3-ol extract from early harvested whole grape clusters. The final product from this process is particularly rich in monomeric and oligomeric flavan-3-ols and with an unusually high conversion of the final product into flavan-3-ol subunits under acid catalysis conditions. The oligomers and polymers in the final product are frequently referred to as proanthocyanidins in the field of polyphenol chemistry. The disclosure provides a novel process for the production of the final product via a continuous extraction process and with a final product having a unique composition.

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20-09-2023 дата публикации

IMPROVEMENTS TO EXTRACTION METHODS, EXTRACTION SYSTEMS, COMPOUNDS AND FORMULATIONS

Номер: EP4244318A1
Принадлежит:

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09-02-1994 дата публикации

NOVEL EXTRACTS OF CUCURBITA SP.,PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICAMENTS AND IN COSMETICS

Номер: GB0009325172D0
Автор:
Принадлежит:

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03-06-2021 дата публикации

Cannabis plants with a cannabinoid profile enriched for Δ-9-tetrahydrocannabinol, cannabigerol and tetrahydrocannabivarin

Номер: AU2019374732A1
Принадлежит:

The present disclosure relates generally to new cannabis plants, including parts, extracts and uses thereof, comprising a cannabinoid profile enriched for total THC (i.e., Δ-9-tetrahydrocannabinol (THC) and Δ-9-tetrahydrocannabinolic acid (THCA), total CBG (i.e.¸ cannabigerol (CBG) and cannabigerolic acid (CBGA)), and total THCV (i.e., tetrahydrocannabivarin (THCV) and tetrahydrocannabivarinic acid (THCVA)).

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07-02-2013 дата публикации

Formulations containing extracts of Echinacea angustifolia and Zingiber officinale which are useful in reducing inflammation and peripheral pain

Номер: AU2011285025A1
Принадлежит:

Disclosed is a combination of lipophilic extracts of Zingiber officinale and Echinacea angustifolia for the treatment of itching, peripheral pain, superficial and deep inflammatory and painful states, pain associated with muscle spasms, herpes pain, and radiodermatitis caused by oncological radiotherapy, with or without fungal or bacterial infections.

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26-03-2020 дата публикации

Phytochemical extraction system and methods to extractphytochemicals from plants including plants of the familycannabaceae sensu stricto

Номер: AU2018314123A1

A method and system of and for extraction or removal of phytochemicals from plants, including those of the plant family Cannabaceae sensu stricto. More specifically, a method and system for extracting essential oils from plants, such as cannabis, without the use of a solvent ...

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08-07-2021 дата публикации

A tonifying and balancing restorative paste

Номер: AU2021102527A4
Автор: GAN AIPING, Gan, Aiping
Принадлежит:

Abstract The present disclosure belongs to the field of pharmaceutical technology, and pertains to a tonifying and balancing restorative paste, containing the ingredients: American Ginseng 15g, Astragalus 45g, Dry-fried Atractylodes macrocephala 45g, Poria cocos 45g, Angelica sinensis 45g, Raw Rehmannia glutinosa 22.5g, Prepared Rehmannia glutinosa 22.5g, Dendrobium 45g, Cortex Phellodendri 22.5g, Dioscorea japonica 30g, Semen Euryales 45g, Ganoderma 45g, Fructus Amomi 15g, Raw White Peony Root 45g, Dong-E-E-Jiao (donkey hide gelatin) 1.5 pieces, Fructus Citri sarcodactylis 15g, Citron Peel 15g, Cortex Moutan 30g, Turmeric Root 30g, Bulbus Fritillariae thunbergii 30g, Asparagus Tuber 30g, and Radix Ophiopogonis 30g. When combined properly, the traditional Chinese medicines in the present disclosure act synergistically, and their toxicity is reduced or eliminated. Its actions include strengthening the spleen and stomach, tonifying qi and blood, and nourishing the liver and kidney. Drawings ...

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15-04-2021 дата публикации

Active components for neonatal intestinal defence and application thereof

Номер: AU2021100175A4
Автор: CAO HONG, Cao, Hong
Принадлежит:

Abstract The invention belongs to the technical field of intestinal defence medicines, and particularly discloses active components for neonatal intestinal defence and application thereof. Specifically, the active components consist of Lactobacillus bulgaricus, Bifidobacterium and Streptococcus thermophilus, which can be applied to the preparation of defensive medicines for treating or preventing neonatal intestinal diseases. Further, the medicines comprise the following components: Lactobacillus bulgaricus, Bifidobacterium, Streptococcus thermophilus, pine pollen, oligosaccharide, vitamins, montmorillonite powder and traditional Chinese medicine extracts. In the invention, the intestinal defence active components can protect the neonatal intestinal barrier and promote the formation of intestinal defence . Moreover, through the synergistic action of the active components, pine pollen, oligosaccharide, vitamin, montmorillonite powder and traditional Chinese medicine extract, the medicine ...

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07-02-2019 дата публикации

POWDERED CANNABIS EXTRACT

Номер: CA0003071897A1
Принадлежит: ROWAND LLP

Powdered cannabis extracts and methods for obtaining powdered cannabis extracts are described. In an aspect, the present application describes a method of preparing a single-serve container which may be configured for receipt in a single-serve brewing machine. The method may include obtaining the cannabis extract which is processed to obtain powdered cannabis, in particular by encapsulation of the extract in sodium caseinate using freeze-drying. The powdered extract is added to the single-serve container which may further include a flavoring agent, and the container is sealed.

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23-03-2017 дата публикации

METHOD AND SYSTEM FOR EXTRACTING COMPOUNDS FROM PLANTS AND PLANT BASED MATERIALS

Номер: CA0003003558A1
Автор: TOMASO, PAUL, TOMASO PAUL
Принадлежит:

The invention provides a method and system for extracting desired compounds from a plant or a plant based material featuring a) providing a plant or plant based material; b) pumping CO2 gas from a CO2 storage vessel into an apparatus containing a CO2 circulation loop; c) circulating CO2 through the plant or plant based material in the circulation loop; d) extracting the desired compounds; and e) discharging the CO2 gas from the CO2 circulation loop. The invention also provides a system for extracting a desired compound from a plant or a plant based material featuring a) an extractor vessel; b) a separator vessel; c) a liquid accumulator; d) at least one hot water valve; e) at least one cold water valve; f) a gas pump; g) a liquid pump; h) at least one two-way valve; i) a three-way valve; and j) a CO2 storage vessel.

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28-03-2019 дата публикации

ISOLATION, PRESERVATION, COMPOSITIONS AND USES OF EXTRACTS FROM JUSTICIA PLANTS

Номер: CA0003076249A1
Принадлежит: LAVERY, DE BILLY, LLP

The present disclosure relates to the isolation, preservation, compositions and uses of extracts from a newly discovered species of Justicia plants. The present disclosure also relates to compositions comprising the extracts of the new species of Justicia plant, as well as methods of producing and using such compositions for treating blood disorders and/or for other health, food and industrial uses.

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22-11-2018 дата публикации

SUBLINGUAL CANNABINOID COMPOSITIONS

Номер: CA0003063613A1
Принадлежит: INTEGRAL IP

The present invention provides novel sublingual muco-adhesive cannabinoid compositions in the form of sublingual tablets or films, exhibiting improved bioavailability and stability, reduced side-effects such as irritation, and optionally lower dosage for the same therapeutic effect, in comparison with an alcohol-based oral spray having 5.2mg of cannabinoid active ingredients per spray.

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29-07-2010 дата публикации

COMPOSITIONS COMPRISING LIPOPHILIC EXTRACTS OF ZINGIBER OFFICINALE AND ECHINACEA ANGUSTIFOLIA FOR THE PREVENTION AND TREATMENT OF GASTRO-OESOPHAGEAL REFLUX AND CHEMOTHERAPY-INDUCED EMESIS

Номер: CA0002750025A1
Принадлежит:

The present invention relates to compositions consisting of a combination of lipophilic extracts of Zingiber officinale and Echinacea angustifolia, obtained by extraction with carbon dioxide under supercritical conditions, which are useful for the prevention and treatment of oesophageal reflux and chemotherapy-induced emesis.

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27-06-2013 дата публикации

HYDROXYMETHYLFURFURAL DERIVATIVE

Номер: CA0002859912A1
Принадлежит:

A hydroxymethylfurfural derivative represented by general formula (A). In the formula, R is selected from the group consisting of formula (I), (II) HOOCCH2COCO-, (III) HOOCCH2CH2COCO-, and (IV) a hydrogen atom.

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10-06-1994 дата публикации

Extracts of Cucurbita SP., Process for Their Preparation and Their Use in Medicaments and in Cosmetics

Номер: CA0002111036A1
Принадлежит:

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31-07-2017 дата публикации

SEEDS OIL S TEARS, CONTAINING 16 GLYCERIDES, AND ITS PHARMACEUTICAL PREPARATION AND ITS APPLICATION

Номер: EA0201790120A1
Автор:
Принадлежит:

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15-03-2019 дата публикации

Supercritical extraction method of rhizoma cyperi phenolic acid compound

Номер: CN0109464564A
Принадлежит:

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01-01-2019 дата публикации

Method for extracting total polyphenol from corn husks

Номер: CN0109106874A
Принадлежит:

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22-03-2017 дата публикации

Pharmaceutical composition for controlling blood lipids and body weight, and use thereof

Номер: CN0106535912A
Автор: ZHOU JAMES
Принадлежит:

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20-07-2018 дата публикации

Ginseng oral liquid for tonifying qi and calming nerve and preparation method thereof

Номер: CN0108295240A
Принадлежит:

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14-09-2018 дата публикации

Child allergic rhinitis ointment and preparation method thereof

Номер: CN0108524682A
Автор: WU RENHUAN, LIU HONGXIA
Принадлежит:

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06-12-2016 дата публикации

COMPOSITION FOR PREVENTING AND TREATING MUSCLE DISEASE OR IMPROVING MUSCULAR FUNCTIONS, CONTAINING BALLOON-FLOWER EXTRACT

Номер: KR1020160138927A
Принадлежит:

The present invention relates to a composition for preventing and treating muscle disease or improving muscular functions, containing a balloon-flower extract. More specifically, the present invention relates to a pharmaceutical composition for preventing and treating muscle disease containing a balloon-flower extract, a food composition for preventing muscle disease or improving muscular functions, or a cosmetic ingredient for improving muscular functions. The balloon-flower extract can promote muscle formation by inducing differentiation of muscle cells as well as myoprotein synthesis, and is derived from natural substances, thereby being safe without side effects. In addition, the balloon-flower extract can be used as an effective component in pharmaceutical, food, or cosmetic compositions showing excellent efficacy on preventing and treating muscle disease or improving muscular functions. COPYRIGHT KIPO 2016 (AA) Balloon-flower extract (10 μg/ml) ...

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21-02-2018 дата публикации

COMPOSITION FOR TREATING ATOPIC DERMATITIS CONTAINING PATRINIA SCABIOSAEFOLIA EXTRACT AS ACTIVE INGREDIENT

Номер: KR101816063B1

Provided is an atopic dermatitis therapeutic agent containing a Patrinia scabiosaefolia extract, which is effective for atopic dermatitis and has few side effects, as an active ingredient. COPYRIGHT KIPO 2018 ...

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22-04-2021 дата публикации

EXTRACTION OF PLANT SOURCE "MEDICINAL SOUP" AND MANUAL PREPARATION OF "HERBAL MEDICINE" AND RELATED PRODUCTS

Номер: US20210113641A1
Принадлежит:

Provided is a method for preparing bencaosome comprising the steps of: mixing one or more lipid components with any one or more of the following: nucleic acid, compound and mancromolecules, and treating the obtained mixture by heating. Also provided is a method for extracting decoctosome from plants comprising the steps of: preparing an extract of the plant with a solvent; performing differential centrifugation to the extract; resuspending the precipitates with an aqueous solution to provide the decoctosome.

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28-04-2020 дата публикации

Method for conducing concentrated cannabis oil to be stable, emulsifiable and flavorless for use in hot beverages and resulting powderized cannabis oil

Номер: US0010631556B2

A method for producing powderized cannabis oil, and the resulting powderized cannabis oil, in which concentrated cannabis oil is mixed with and absorbed by a modified starch powder, preferably maltodextrin, in a ratio of at least three grams of starch powder for every one-eighth of a gram of cannabis oil is disclosed. Further disclosed are beverages, baked goods and single-serve beverage brewing cartridges utilizing or incorporating the powderized cannabis oil to create human-consumable products that contain an emulsified, tasteless, and odorless dose of cannabis oil.

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20-04-2021 дата публикации

Essential oil manufacturing

Номер: US0010982899B1
Принадлежит: GELARDI PAUL JOSEPH, Gelardi Paul Joseph

Botanical materials are dehydrated, ruptured and comminuted into particles by blades or whips in a fluidized bed. Particles separated from a drying gas are transferred to reduced pressure insulated vessels. Solvents dissolve components of the particles under precise temperature control. Solvents are recirculated and distilled to recover distillates. Distillates are refined by thermal and pressure changes to remove fats, waxes and contaminants and are fractionated to specific essential oils. The essential oils are tested, winterized, filtered, decarboxilated, polished, diluted and discharged into collection vessels. The collected essential oils are pumped through needles into sealed cartridges. The cartridges are tamper-proofed, printed and labeled with batch, botanical source, process, tracking and tracing information and codes.

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07-07-2022 дата публикации

IMMUNOSTIMULATOR AND METHOD FOR PREVENTING INFECTION

Номер: US20220211786A1
Принадлежит: Asahi Group Holdings, Ltd.

Provided is an immunostimulator containing glucan and having an immunostimulatory effect. This immunostimulator contains glucan and lipid derived from yeast cell wall and is water-insoluble. A total content percentage of glucan and lipid is 80 mass % or more, and a content ratio of lipid to glucan is 0.1 or more and 0.4 or less.

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01-06-2023 дата публикации

ANTIDEPRESSANT FOOD AND METHOD FOR PREPARING THE SAME

Номер: US20230165926A1
Автор: Hanping Shi, Ru Jia
Принадлежит:

An antidepressant food and a method for preparing the same are provided. The antidepressant food includes, by mass percentage, Semen ziziphi spinosae powder in a range of 28% to 36%, γ-aminobutyric acid in a range of 10% to 15%, theanine in a range of 15% to 20%, phosphatidylserine in a range of 10% to 20%, Ficus tikoua extract in a range of 8% to 14%, Huperzia serrata extract in a range of 10% to 16%, sucralose in a range of 0.5% to 1% and fruit essence in a range of 0.5% to 1.5%.

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14-05-2014 дата публикации

APPLICATION OF PRODUCTS OF COFFEE SILVERSKIN IN ANTI-AGEING COSMETICS AND FUNCTIONAL FOOD

Номер: EP2730171A1
Принадлежит:

The invention relates to a product obtained from coffee silverskin, characterised in that it is (a) powdered coffee silverskin or b) coffee silverskin extract. The invention also relates to a method for extracting coffee silverskin, comprising a step of extraction with water, preferably with subcritical water. The invention further relates to the use of the product obtained from coffee silverskin in cosmetics or functional food, especially for preventing physiological ageing processes, as a food preservative for preventing oxidative processes and as a source of caffeine.

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02-11-2018 дата публикации

ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ ДЛЯ ПРОФИЛАКТИКИ И ЛЕЧЕНИЯ СЕНИЛЬНОЙ ДЕМЕНЦИИ И СПОСОБ ЕЁ ПОЛУЧЕНИЯ

Номер: RU2671566C2

Настоящее изобретение относится к фармацевтической промышленности, а именно к композиции для профилактики и лечения сенильной деменции. Фармацевтическая композиция для лечения или профилактики сенильной деменции, отличающаяся тем, что активные ингредиенты фармацевтической композиции получают из сырьевых лекарственных материалов, состоящих из листьев эпимедиума (лат. Epimedii Folium), экстрагированного этанолом, и пории, экстрагированной водой, взятых в определенном соотношении (варианты). Способ получения фармацевтической композиции для лечения или профилактики сенильной деменции (варианты). Вышеописанная композиция эффективна для лечения или профилактики сенильной деменции. 14 н. и 20 з.п. ф-лы, 9 табл., 5 пр.

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20-10-2015 дата публикации

КОМПОЗИЦИИ, СОДЕРЖАЩИЕ ЭКСТРАКТЫ Echinacea angustifolia И Zingiber officinale, КОТОРЫЕ ПОЛЕЗНЫ ДЛЯ УМЕНЬШЕНИЯ ВОСПАЛЕНИЯ И ПЕРИФЕРИЧЕСКОЙ БОЛИ

Номер: RU2565436C2
Принадлежит: ИНДЕНА С.П.А. (IT)

Изобретение относится к фармацевтической промышленности, а именно к композиции и комбинации для применения в лечении зуда, периферической боли, воспалительных и болезненных состояний, радиационного дерматита, вызванного лучевой терапией рака, отека и состояний раздражения кожи, включая состояния, обусловленные чрезмерным воздействием солнечного света. Комбинация липофильных экстрактов Zingiber officinale и Echinacea angustifolia, содержащая изобутиламиды из Echinacea angustifolia и гингерол из Zingiber officinale, в которой экстракты обоих видов растений получают из корней или корневищ экстракцией сверхкритическим диоксидом углерода. Композиция, содержащая комбинацию липофильных экстрактов Zingiber officinale и Echinacea angustifolia. Вышеописанные комбинация и композиция эффективны для лечения зуда, периферической боли, воспалительных и болезненных состояний, радиационного дерматита, вызванного лучевой терапией рака, отека и состояний раздражения кожи, включая состояния, обусловленные ...

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11-10-2019 дата публикации

СПОСОБ ПРЕОБРАЗОВАНИЯ МАТЕРИАЛОВ ЯГОД И ФРУКТОВ В ПРОТИВОМИКРОБНО АКТИВНЫЕ ФРАКЦИИ

Номер: RU2702860C2

Изобретение относится к пищевой промышленности. Способ преобразования материалов ягод и/или фруктов во фракции, содержащие биологически активные соединения, включает стадии, где по меньшей мере один материал ягод или материал фруктов, выбранный из ягод, фруктов, побочных продуктов, боковых фракций и материалов отходов, получаемых из ягод или фруктов, и любых их комбинаций, просеивают, при этом фракция семян отделяется от фракции кожуры, фракцию семян подвергают шлифованию, где 2-40 % мас. поверхностного слоя семян удаляется, и получают фракцию оболочек семян, содержащую указанный поверхностный слой семян, и фракцию шлифованных семян, содержащую шлифованные семена, причем фракция оболочек семян содержит биологически активные фенольные соединения. Ягоды выбирают из рода Rubus, Sorbus, Rosa, Empetrum, Aronia и Hippophae и из их комбинаций. Фрукты выбирают из рода Vitis и Punica и их комбинаций. Полученные фракции оболочек семян в качестве средства с противомикробной активностью применяют в ...

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27-07-2014 дата публикации

КОМПОЗИЦИИ, СОДЕРЖАЩИЕ ЛИПОФИЛЬНЫЕ ЭКСТРАКТЫ ZINGIBER OFFICINALE И ECHINACEA ANGUSTIFOLIA, ДЛЯ ПРЕДУПРЕЖДЕНИЯ И ЛЕЧЕНИЯ ГАСТРОЭЗОФАГЕАЛЬНОГО РЕФЛЮКСА И РВОТЫ, ВЫЗВАННОЙ ХИМИОТЕРАПИЕЙ

Номер: RU2524625C2
Принадлежит: ИНДЕНА С.П.А. (IT)

Изобретение относится к фармацевтической промышленности, а именно к композиции для предупреждения и лечения эзофагеального рефлюкса. Композиция для предупреждения и лечения эзофагеального рефлюкса, содержащая липофильный экстракт Zingiber officinale и липофильный экстракт Echinacea angustifolia, в определенных весовых диапазонах, полученные путем экстракции суперкритическим диоксидом углерода. Применение липофильного экстракта Zingiber officinale: и липофильного экстракта Echinacea angustifolia, взятых в определенных весовых диапазонах, для предупреждения и лечения эзофагеального рефлюкса. Вышеописанная композиция эффективна для предупреждения и лечения эзофагеального рефлюкса. 2 н. и 4 з.п. ф-лы, 2 пр.

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27-02-2013 дата публикации

КОМПОЗИЦИИ, ВКЛЮЧАЮЩИЕ ЛИПОФИЛЬНЫЙ ЭКСТРАКТ ZINGIBER OFFICINALE И ЭКСТРАКТ CYNARA SCOLYMUS, КОТОРЫЕ ИСПОЛЬЗУЮТСЯ ДЛЯ ПРОФИЛАКТИКИ И ЛЕЧЕНИЯ ГАСТРОЭЗОФАГЕАЛЬНОГО РЕФЛЮКСА И СИНДРОМА ВОСПАЛЕННОЙ КИШКИ

Номер: RU2011129991A
Принадлежит:

... 1. Композиции, содержащие:Липофильный экстрактполученный экстракцией диоксидом углерода в сверхкритических условиях; иэкстракт2. Композиции по п.1, содержащие два компонентав следующих весовых диапазонах:a) липофильный экстрактот 1 до 25 мг иb) экстрактот 50 до 200 мг.3. Композиции по п.2, содержащие два компонента в следующих весовых количествах:a) липофильный экстракт12,5 мг иb) экстракт100 мг.4. Композиции по п.1, отличающиеся тем, что экстрактполучают путем экстракции надземных частей растения спиртом или водноспиртовым растворителем и фракционирования на смоле.5. Композиции по п.1, отличающиеся тем, что содержащийся в них экстрактсодержит не менее 20% кофеоилхинных кислот, не менее 5% флавоноидов и не менее 5% цинаропикрина.6. Композиции по любому из указанных выше пунктов для перорального введения.7. Композиции по п.6, представленные в форме мягких желатиновых капсул или целлюлозных капсул, подходящих для включения в них маслянистых веществ.8. Применение:a) липофильного экстрактаполученного ...

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31-05-2017 дата публикации

СРЕДСТВО ДЛЯ ЛЕЧЕНИЯ СПАЕЧНОЙ БОЛЕЗНИ

Номер: RU2621131C1

Изобретение относится к фармацевтической промышленности, в частности к средству для лечения спаечной болезни брюшины. Средство для лечения спаечной болезни брюшины для приема вовнутрь, которое содержит водное извлечение из корневищ аира болотного, травы зверобоя продырявленного, корней солодки голой, полученное из корневищ аира болотного, травы зверобоя продырявленного, корней солодки голой, воды питьевой, взятое при определенном содержании компонентов. Вышеописанное средство эффективно для лечения спаечной болезни брюшины. 2 пр.

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09-08-2017 дата публикации

СПОСОБ ПОЛУЧЕНИЯ БИОЛОГИЧЕСКИ АКТИВНОЙ ДОБАВКИ К ПИЩЕ ИЗ РАСТИТЕЛЬНОГО СЫРЬЯ

Номер: RU2627590C1

Изобретение относится к способу получения биологически активной добавки к пище из листьев и (или) цветков персика. Способ получения биологически активной добавки к пище включает подготовку сырья - листьев и/или цветков персика обыкновенного, которое заливают очищенной водой, проводят первичное экстрагирование, полученный экстракт отделяют от растительной массы, полученный в конце способа концентрат консервируют, при этом при подготовке сырья из него удаляют некондиционные части, измельчают, после 1-го экстрагирования повторно проводят 2 экстрагирования при тех же условиях с добавлением к растительной массе воды очищенной, полученные экстракты объединяют и фильтруют, объединенный экстракт концентрируют в условиях вакуума, полученный первичный концентрат охлаждают и подвергают очистке, концентрат декантируют и фильтруют или центрифугируют, отделяя взвесь от балластных веществ, проводят вторичное концентрирование, а для консервации используют кислоту сорбиновую или сорбат калия до содержания ...

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14-04-2021 дата публикации

Methods of treating tuberous sclerosis complex with cannabibiol and everolimus

Номер: GB202102853D0
Автор:
Принадлежит:

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09-03-2016 дата публикации

Botanical compositions of salvia officinalis with activity in extending chronological lifespan and methods of use

Номер: GB0201601520D0
Автор:
Принадлежит:

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31-05-2023 дата публикации

Ozonation of cannabinoids

Номер: GB0002567235B
Принадлежит: MICHAEL DANIEL MAYERS [GB]

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27-03-2014 дата публикации

Plant derived seed extract rich in essential fatty acids derived from perilla seed: composition of matter, manufacturing process and use

Номер: AU2011376919A1
Принадлежит:

A composition of matter comprises a shelf stable, super critical, CO2 fluid extracted seed oil derived from a cracked biomass of perilla frutescens, the seed oil comprising from about 60 to about 95 percent w/w of PUFAs in a ratio of from about 4:1 to about 6:1 alpha-linolenic acid (ALA) to linoleic acid (LA) and a mixture of selected antioxidants.

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03-06-2021 дата публикации

Plants with a cannabinoid profile enriched for cannabidiol

Номер: AU2019375921A1
Принадлежит:

The present disclosure relates generally to new cannabis plants, including parts, extracts and uses thereof, comprising a cannabinoid profile enriched for total CBD ( ...

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24-12-2019 дата публикации

CLOSED-LOOP MULTI-STAGE CHILLED FILTER SYSTEM

Номер: CA0003023563C

A series of vertically oriented filters of decreasing pore size is sealed from the atmosphere. Pressurized gas is used to force the liquid to be filtered through the filters. The filter stages are thermally insulated from ambient temperatures in order to maintain the liquid passing through at a reduced temperature. Each filter stage has a removable lid, which provides convenient access for replacing the filter cartridge, allowing it to be changed without disturbing the thermally insulated sidewalls of the filter stage.

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14-06-2018 дата публикации

SYSTEMS AND METHODS FOR EXTRACTION OF NATURAL PRODUCTS

Номер: CA0003046011A1
Принадлежит: LOOPSTRA NIXON LLP

Described herein, inter alia, are processes, methods, and compositions useful for the extraction of natural products from source materials.

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29-05-2018 дата публикации

PHARMACEUTICAL COMPOSITION FOR TREATING ECZEMA AND METHOD FOR PREPARATION THEREOF

Номер: CA0002986991A1
Автор: YU, LUPING, YU LUPING
Принадлежит:

A pharmaceutical composition for treating eczema is disclosed. The pharmaceutical composition includes, by weight, 2 to 6 parts of Dried Rhizoma Zingiberis Officinalis, 2 to 6 parts of Paeonia Lactiflora, 1. to 4 parts of Fructus Amomi, 0.5 to 3 parts of Semen Alpiniae Katsumadai, 0.5 to 3 parts of Inula helenium, 0.5 to 3 parts of Radix Et Rhizoma Rhei and 0.5 to 3 parts of,Rhizoma Dioscoreae. The components of the pharmaceutical composition synergistically cooperate to clear and disinhibit the liver and gallbladder and clear away damp heat from the body. The pharmaceutical composition can be used to treat skin eczema symptoms caused by metabolic disorders of the liver and gallbladder functions. A method for preparing the pharmaceutical composition is also disclosed.

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24-10-2013 дата публикации

METHOD FOR REFINING SQUALENE PRODUCED BY MICROALGAE

Номер: CA0002869358A1
Принадлежит:

L'invention se rapporte à un procédé de préparation d'une composition à haute richesse en squalène produit par fermentation de microorganismes, caractérisé en ce qu'il comprend une étape de purification choisie dans le groupe constitué de l'extraction par CO2 supercritique sur colonne de fractionnement multiétagée fonctionnant à contre-courant avec reflux d'extrait,et de la distillation moléculaire dite de «court trajet».

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02-07-2019 дата публикации

OBTAINING A JUICE OF FRESH PLANTS BY THERMOMECHANICAL TREATMENT AND COSMETIC AND THERAPEUTIC USE THEREOF

Номер: CA0002924532C

La présente invention concerne un procédé d'obtention d'un jus de plantes fraîches, caractérisé en ce que lesdites plantes fraîches, à l'exclusion des graines seules, sont soumises à un traitement thermomécanique consistant à extruder les plantes fraîches dans un extrudeur, associé à un traitement thermique permettant d'inactiver les enzymes endogènes et de conserver les molécules de composés d'intérêt sous leur forme native, en l'absence de solvant, suivi d'une opération de récupération du jus.

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01-08-2000 дата публикации

EXTRACTS OF CUCURBITA SP., PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICAMENTS AND IN COSMETICS

Номер: CA0002111036C
Принадлежит: Indena S.p.A.

A process for the preparation of novel extracts of Cucurbita pepo and cultivars thereof, the extracts obtainable thereby and their use in pharmacy and cosmetics are described. The said process comprises the following stages: a) the milling of the Cucurbita seeds, where appropriate b) the extraction of the milled Cucurbita seeds with supercritical carbon dioxide at a temperature from 34 to 50.degree.C and under a pressure between 110 and 150 bar to remove unwanted products, c) the extraction of the active substances from the milled Cucurbita seeds with carbon dioxide under super-critical conditions or with organic solvents and d) the purification of the resulting extract by fractional countercurrent extraction with carbon dioxide under supercritical conditions. These extracts are used for the treatment of benign prostate hypertrophy and related clinical manifestations. The extracts are employed in cosmetics for the treatment of juvenile acne and as antiseborrhoea agents.

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31-07-2018 дата публикации

Lung cancer rehabilitation solution and preparation method thereof

Номер: CN0108339062A
Автор: GUO QIAOQIN
Принадлежит:

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02-06-2017 дата публикации

ALCOHOLIC EXTRACT OF AERIAL PARTS OF A SOLIDAGO VIRGAUREASUBSP. ALPESTRIS, PRODUCTION METHOD THEREOF, AND COSMETIC OR DERMATOLOGICAL COMPOSITION CONTAINING THE SAME

Номер: FR0003044226A1

L'invention concerne un extrait alcoolique de parties aériennes de Solidago virgaurea subsp. alpestris, son procédé d'obtention, une composition cosmétique ou dermatologique le contenant, ainsi que ses utilisations cosmétiques et dermatologiques, notamment dans le traitement des signes cutanés du vieillissement.

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08-03-2018 дата публикации

올리고당이 함유된 죽경 추출물에 의한 동맥경화증 예방 및 치료용 조성물

Номер: KR0101821109B1
Автор: 박월선, 신순영
Принадлежит: 서우산업주식회사

... 본 발명은 죽경 추출물의 새로운 용도에 관한 것으로서, 더욱 상세하게는 올리고당이 함유되어있는 죽경 추출물을 함유하는 동맥경화증 예방 또는 치료용 약학 조성물에 관한 것이다. 상기와 같은 본 발명에 따르면, 올리고당 함유 죽경 추출물이 함유된 조성물은 혈소판유래세포성장인자(platelet-derived growth factor; PDGF)에 의한 혈관평활근세포 증식과 이동을 억제하는 효과가 있으며, TNF-α에 의해 유도되는 NF-κB 활성을 억제하여 세포 부착단백질들 (ICAM-1과 VCAM-1)의 유전자 발현과 염증 매개 인자(IL-6와 iNOS) 들의 유전자 발현을 억제시킴으로써, 동맥경화증 또는 혈관 염증 질환의 예방 및 치료, 치료 개선을 위한 약학적 조성물 또는 건강기능성 식품의 개발에 널리 활용될 수 있을 것이다.

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08-04-2020 дата публикации

COMPOSITION HAVING ANTIBACTERIAL ACTIVITY FOR STREPTOCOCCUS MUTANS

Номер: KR0102098950B1
Автор:
Принадлежит:

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08-05-2017 дата публикации

PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING EDEMA OR INFLAMMATION CONTAINING ORIENTAL MEDICINE HERB FAT-SOLUBLE FRACTIONAL EXTRACT AS ACTIVE INGREDIENT

Номер: KR1020170047555A
Принадлежит:

The present invention relates to a pharmaceutical composition for preventing or treating edema or inflammation containing an oriental medicine herb fat-soluble fractional extract as an active ingredient. The composition contains an extract in which one or more types selected from the group consisting of Dictamnus dasycarpus Turcz, Cnidium officinale Makino and Angelica gigas Nakai are extracted by a supercritical extraction method, thereby preventing and treating edema or inflammation such as myositis, dermatitis, etc. COPYRIGHT KIPO 2017 (AA) Cell viability (Random unit) (BB) Example 2 (μg /mL) ...

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07-11-2018 дата публикации

어성초 추출물을 유효성분으로 포함하는 항산화, 항염증용 및 피부 재생용 조성물

Номер: KR0101915952B1

... 본 발명의 어성초 추출물은 효소 처리 및 초고압 균질화 처리를 포함하는 추출방법으로 추출된 것으로, 상기 추출방법은 불용성 섬유질 성분을 가용화시켜 추출 수율과 생리활성이 증진되며, 부산물의 발생을 감소시켜 제조 단계 측면에서도 경쟁력을 확보할 수 있다. 또한, 본 발명의 어성초 추출물을 유효성분으로 포함하는 항산화 및 항염증용 조성물은 항산화기능과 염증 매개물질인 NO의 발생을 억제하므로, 항산화 및 항염증용 화장료 조성물 및 염증성 질환의 예방 및 치료용 약학 조성물로서 유용하게 사용될 수 있다.

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08-12-2011 дата публикации

PROCESS FOR EXTRACTING PLANT-DERIVED NATURAL PRODUCTS WITH POLARITY OR INTERMEDIATE POLARITY

Номер: WO2011150536A1
Принадлежит:

A process for extracting plant-derived natural products with polarity or intermediate polarity is provided. Said process involves the following steps: crushing the plant-derived materials containing natural products with polarity or intermediate polarity, adding water, and circularly introducing CO2 with high pressure into the extracting apparatus. During the extracting process, the temperature is 40-90℃, the pressure is 5-50 MPa, and the treatment time with high pressure CO2 is 1-60 minutes. Said process can be used to extract polar natural products such as anthocyanins, or other natural products with polarity or intermediate polarity.

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30-01-2020 дата публикации

METHOD FOR PRODUCING FERMENTED BAMBOO EXTRACT AND IMMUNOSTIMULATING AGENT

Номер: US20200029610A1
Принадлежит: Individual

An object of the present invention is to provide a new application of bamboo based on new functions. A method for producing a fermented bamboo extract comprises a pulverization step of pulverizing bamboo to obtain bamboo powder, a fermentation step of fermenting the bamboo powder with lactic acid bacteria to obtain a fermented bamboo product, and an extraction step of subjecting the fermented bamboo product to hot water extraction to obtain an extract.

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07-03-2019 дата публикации

TRADITIONAL CHINESE MEDICINE COMPOSITION AND USE THEREOF

Номер: US2019070237A1
Принадлежит:

The present disclosure relates to the field of drugs and health foods. Disclosed is a traditional Chinese medicine composition comprising GANODERMA polysaccharide, GRIFOLA FRONDOSA polysaccharide, ANGELICAE SINENSIS RADIX oil and CINNAMOMI CORTEX oil. Experiments show that the traditional Chinese medicine composition has a scientific formulation, synergistic functions, without toxic and side effects, and not only has nutritional value but also inhibits the growth of tumor. Comparing with individual components, the composition significantly increases the percentages of CD4+ and CD8+ cells in lymphocytes of the tumor stroma, increases body immune function, recovers normal immune surveillance function, decreases the expression rate of VEGF and TGF-β 1 positive cells in tumor tissue, assists in treating tumor, increases antitumor effects of chemotherapy drugs, improves immune status of body, has the function of restoring normal immune surveillance, preventing and assisting in treating tumor ...

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12-10-2022 дата публикации

METHOD FOR TRANSFORMING AN ESSENTIAL OIL

Номер: EP4069221A1
Принадлежит:

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16-07-2020 дата публикации

Method and composition for treating viral infection

Номер: AU2020204236A1
Принадлежит: Spruson & Ferguson

METHOD AND COMPOSITION FOR TREATING VIRAL INFECTION Abstract A method of treating viral infection, such as viral infection caused by a virus of the Filoviridae, Flaviviridae or Togaviriade family, is provided. A composition having at least one cardiac glycoside is used to treat viral infection. The composition can further include at least one triterpene.

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26-07-2012 дата публикации

Tangerine peel extract and its preparation and application

Номер: US20120189731A1
Принадлежит: Infinitus China Co Ltd

This invention disclosed is a tangerine peel extract with the effect of weight gain. This extract uses tangerine peel as the raw ingredient and is obtained through extraction processes using supercritical CO 2 , water, or organic solvents. The resulting extraction component contains a large quantity of flavonoids and terpenoids, which can effectively regulate the function of the spleen and stomach leading to desired weight gain. This invention also declares the preparation methods of the above mentioned tangerine peel extraction, which is simple in technique and highly effective in extraction. This invention also further declares the application of the above mentioned tangerine peel extraction in preparing healthcare food with the function of gaining weight.

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03-01-2013 дата публикации

Sandalwood oil and its uses

Номер: US20130005830A1
Принадлежит: SANTALIS PHARMACEUTICALS Inc

Provided herein are compositions of sandalwood oil and methods of making and using such compositions.

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02-05-2013 дата публикации

Compositions comprising lipophilic extracts of zingiber officinale and echinacea angustifolia for the prevention and treatment of gastro-oesophageal reflux and chemotherapy-induced emesis

Номер: US20130108720A1
Автор: Ezio Bombardelli
Принадлежит: Indena SpA

The present invention relates to compositions consisting of a combination of lipophilic extracts of Zingiber officinale and Echinacea angustifolia , obtained by extraction with carbon dioxide under supercritical conditions, which are useful for the prevention and treatment of oesophageal reflux and chemotherapy-induced emesis.

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10-10-2013 дата публикации

Formulations containing extracts of echinacea angustifolia and zingiber officinale which are useful in reducing inflammation and peripheral pain

Номер: US20130266672A1
Принадлежит: Indena SpA

Disclosed is a combination of lipophilic extracts of Zingiber officinale and Echinacea angustifolia for the treatment of itching, peripheral pain, superficial and deep inflammatory and painful states, pain associated with muscle spasms, herpes pain, and radiodermatitis caused by oncological radiotherapy, with or without fungal or bacterial infections.

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02-01-2020 дата публикации

CONCENTRATE AND PRODUCTS CONTAINING KAVA, AND METHODS OF MAKING THE SAME

Номер: US20200000135A1
Автор: Munsell Michael
Принадлежит:

Embodiments herein relate to a concentrate of a kavalactone and methods for making the same, as well as products containing the concentrate, the concentrate comprising a noble kava comprising kavain, dihydrokavain, methysticin, dihydromethysticin, yangonin, and desmethoxyyangonin, wherein the concentrate comprises 10% or more of the kavalactone as measured by HPLC. 1. (canceled)2. (canceled)3. The product of claim 7 , wherein the kavalactone extract comprises 70% or more by weight of the kavalactones as measured by HPLC.4. The product of claim 7 , wherein the kavalactone extract comprises 80% or more by weight of the kavalactones as measured by HPLC.5. The product of claim 7 , wherein the kavalactone extract is obtained from a selected part of a kava plant claim 7 , wherein the selected part comprises a lower part of a basal stem claim 7 , a rhizome and/or a root.6. (canceled)7. A product comprising a kavalactone extract comprising kavalactones comprising at least 50% of two or more of kavain claim 7 , dihydrokavain claim 7 , methysticin claim 7 , dihydromethysticin claim 7 , yangonin claim 7 , and desmethoxyyangonin of a total kavalactones claim 7 , wherein the kavalactone extract is an extract of a noble kava claim 7 , wherein the product comprises a beverage claim 7 , an aerated beverage claim 7 , a candy claim 7 , a confectionary claim 7 , an effervescent powder or tablet claim 7 , or a dietary supplement claim 7 , and wherein the product is edible or drinkable in a solid form claim 7 , a powder form claim 7 , a paste form or a liquid form claim 7 , wherein the product comprises the kavalactone extract claim 7 , wherein the kavalactone extract is formed by contacting the noble kava with an extraction agent comprising supercritical CO claim 7 , wherein the kavalactone extract comprises 60% or more by weight of the kavalactones as measured by HPLC claim 7 , wherein the kavalactone extract is in the liquid form.8. The product of claim 5 , wherein the selected part ...

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06-01-2022 дата публикации

ENVIRONMENTALLY-FRIENDLY PREPARATION METHOD OF COMPOSITION CONTAINING ANTI-INFLAMMATORY ACTIVE INGREDIENTS AND USE OF COMPOSITION

Номер: US20220000956A1
Принадлежит: SHANGHAI JAKA BIOTECH CO., LTD.

An environmentally-friendly preparation method of a composition containing anti-inflammatory ingredients and use of the composition are provided. The method includes: S1. weighing a specified volume of water and adjusting the pH, adding roots, and subjecting a resulting mixture to extraction at a high temperature; S2. adjusting pH of an obtained solution in step S1, adding roots, and heating a resulting mixture to boiling for extraction; S3. adding roots to an obtained boiling solution from the extraction in step S2, and subjecting a resulting mixture to extraction, filtration, and pH adjustment; S4. adding activated carbon to an obtained filtrate in step S3, and subjecting a resulting mixture to incubation and filtration; S5. adding a clarifying agent to an obtained filtrate in step S4, and subjecting a resulting mixture to standing and filtration; and S6. subjecting an obtained filtrate in step S5 to membrane separation. 1. An environmentally-friendly preparation method of a composition containing anti-inflammatory active ingredients , comprising the following steps:{'i': 'Sophora flavescens', 'S1. weighing a predetermined volume of water and adjusting a pH of the predetermined volume of water, adding roots to obtain a first resulting mixture, and subjecting the first resulting mixture to a first extraction at a predetermined temperature to obtain an extracted solution;'}{'i': 'Glycyrrhiza inflata', 'S2. adjusting a pH of the extracted solution obtained in step S1, adding roots to obtain a second resulting mixture, and heating the second resulting mixture to boiling for a second extraction to obtain an extracted boiling solution;'}{'i': 'Scutellaria baicalensis', 'S3. adding roots to the extracted boiling solution obtained in step S2 to obtain a third resulting mixture, and subjecting the third resulting mixture to a third extraction, a first filtration, and a pH adjustment to obtain a first filtrate;'}S4. adding activated carbon to the first filtrate obtained in ...

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07-01-2021 дата публикации

COMPOSITON FOR PREVENTING OR TREATING OSTEOPOROSIS

Номер: US20210000900A1
Автор: Kim Hong Sik
Принадлежит:

The present invention relates to a composition for preventing or treating osteoporosis, comprising a extract and a extract, and it is an object of the present invention to provide the composition for preventing or treating osteoporosis, which is capable of increasing bone formation and inhibiting bone resorption. In addition, it is another object of the present invention to provide the composition for preventing or treating osteoporosis, which increases bioaffinity and has no side effects by comprising a extract and a extract, which are natural products, thereby stably exhibiting an effect of preventing or treating osteoporosis. 1Gentiana scabraSambucus williamsii. A composition comprising a extract and a extract.2Gentiana scabraSambucus williamsii. The composition according to claim 1 , wherein the mixing weight ratio of the extract and the extract is 1:0.1 to 10.3Gentiana scabraSambucus williamsii. The composition according to claim 1 , wherein the composition comprises the extract and the extract in an amount of 0.001 to 100% by weight claim 1 , based on the total weight of the total composition.4Gentiana scabraSambucus williamsii. The composition according to claim 1 , wherein the extract and the extract are extracted by hot water extraction.5. The composition according to claim 1 , wherein the composition improves expression of a gene related to bone formation.6. The composition according to claim 5 , wherein the gene related to bone formation is one or more gene selected from the group consisting of ALP claim 5 , osteocalcin claim 5 , BMP claim 5 , TGF-β claim 5 , and osteoprotegerin.7. The composition according to claim 1 , wherein the composition inhibits expression of a gene related to bone resorption.8. The composition according to claim 7 , wherein the gene related to bone resorption is one or more gene selected from the group consisting of NF-kB claim 7 , c-FOS claim 7 , NFATC-1 claim 7 , Cathepsin K claim 7 , and MMP-9.9. A method of preparing the ...

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07-01-2021 дата публикации

METHOD FOR OBTAINING AN EXTRACT ENRICHED IN ROSMARINIC ACID FROM FRESH PLANT MATERIAL

Номер: US20210000901A1
Принадлежит:

Methods for obtaining an extract enriched in rosmarinic acid from fresh plant material selected from the fresh aerial parts, flowering tops, flowers and/or leaves of plants from the family Lamiaceae, Araliaceae, Boraginaceae, Apiaceae, Poaceae and Malvaceae. The methods include steam bleaching the plant material followed by continuous expression with at least one compression screw, under pressure of between 4 and 10 bar from which the sap (liquid co-product) is recovered. Then, the sap is filtered to produce a clarified sap and is subsequently atomized to obtain a granulated or finely powdered extract containing at least 5% of rosmarinic acid in weight relative to the total weight of the extract. Compositions having such an extract as an active agent are disclosed. The compositions are used in the food, cosmetic, nutraceutical and pharmaceutical fields. 1. A method for obtaining an extract enriched in rosmarinic acid from fresh plant material selected from the fresh aerial parts , flowering tops , flowers and/or leaves of plants from the family Lamiaceae , the method comprising:1) steam bleaching said plant material for less than 2 hours at atmospheric pressure at a temperature of 100° C.;2) continuous expressing with at least one compression screw, under pressure between 4 and 10 bar, of the plant material bleached in 1) with recovery of the sap;3) filtering the recovered sap in 2) to produce a clarified sap; and4) atomizing the clarified sap to obtain a granulated or finely powdered extract containing at least 5% of rosmarinic acid in weight relative to the total weight of the extract.2. (canceled)3. (canceled)4SalviaRosmarinus officinalisOriganum vulgareMentha piperitaSatureja hortensisMelissa officinalis. The method according to claim 1 , wherein the plant material is selected from sage (ssp) claim 1 , rosemary () claim 1 , oregano () claim 1 , mint () claim 1 , summer savory (L.) claim 1 , and lemon balm (L.).5. (canceled)6. The method according to claim 1 , ...

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13-01-2022 дата публикации

SEMI-AQUEOUS METHOD FOR EXTRACTING A SUBSTANCE

Номер: US20220008839A1
Принадлежит: Clean Imagineering LLC

A semi-aqueous method for extracting a substance. The method involves combining a first liquid or solid substance containing an extract with a semi-aqueous solution containing a water-soluble or water-emulsifiable (WSWE) compound. Said WSWE compound selectively dissolves extract during a dense phase COexpansion and salting-out process, which is simultaneously co-extracted using said dense phase CO, and desolvated to produce a COsalted-out solvent mixture containing extract. Said COsalted-out solvent mixture is treated using various secondary processes. The present invention is useful for producing extracts for use as additives in pharmaceuticals, nutraceuticals, cosmetics, beverages, or foods, and for quantitative analysis. 1. A semi-aqueous extraction method for recovering an extract from a substance , the steps comprising:a. Placing the substance into a pressure vessel;b. Adding a semi-aqueous solution, comprising a mixture of water and water-soluble or water-emulsifiable compound, to the pressure vessel;{'sub': '2', 'c. Pressurizing said semi-aqueous solution and the substance using dense phase COto establish a tunable extraction system in the pressure vessel;'}{'sub': '2', 'd. Expanding and salting-out said tunable extraction system using said dense phase COto produce a first separated phase, which comprises the water-soluble or water-emulsifiable compound containing the extract; and'}{'sub': 2', '2, 'e. Simultaneously co-extracting said first separated phase into said dense phase COto produce a second separated phase, which comprises a COsalted-out solvent mixture containing the extract.'}2. The semi-aqueous extraction method of claim 1 , wherein said substance comprises natural product claim 1 , pomace claim 1 , animal tissue claim 1 , soil claim 1 , sludge claim 1 , slurry claim 1 , potable water claim 1 , alcoholic beverage claim 1 , fermentation broth claim 1 , industrial wastewater claim 1 , fermented food claim 1 , or water-based extractant.3. The semi- ...

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11-01-2018 дата публикации

Press device and method for producing resinous plant extract

Номер: US20180008655A1
Автор: Kasse Weikel
Принадлежит: Individual

The invention is a rosin press that is adapted for operation in two dimensions so that collection efficiency and amount of rosin from the device is maximized which allows for larger quantity operation and faster production. The press applies pressure to a quantity of resinous plant material placed between a pair of heated platens to initiate a flow of rosin. The press can be quickly and easily rotated from a first dimension to a second dimension so that the flow of rosin can fall by gravity to a chilled surface and be more easily collected while preserving quality. The invention can apply to any resinous plant.

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11-01-2018 дата публикации

Preparation Method of the Albumin Peptide Combination and the Action of Inhibiting the Proliferation of Cancer Cells Thereof

Номер: US20180008678A1
Принадлежит: Nascent Peptide Biotechnology Ltd

The present invention discloses a preparation method of an albumin peptide combination and the action of inhibiting the proliferation of cancer cells thereof, the preparation steps comprise: mixing albumin and water in proportion, heating, adjusting pH, adding alkaline protease to perform enzymatic hydrolysis, deactivating, filtrating; mixing coix seed and water in proportion, decocting to extract, filtrating, adding certain proportional of water to filter residue, continue decocting to extract, collecting filtrates, determining solid matter content respectively, mixing two solutions, concentrating, spray drying, and obtaining an albumin peptide combination having the action of inhibiting the proliferation of cancer cells. The present invention found that, as compared with using coix seed individually, the effect of inhibiting the proliferation of cancer cells of albumin peptide combination is stronger, and process is simpler.

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14-01-2021 дата публикации

COMPOSITION FOR RELIEVING STRESS AND ENHANCING IMMUNITY AND PREPARATION METHOD THEREOF

Номер: US20210008124A1
Принадлежит:

The invention belongs to the technical field of health food and particularly relates to a composition for relieving stress and enhancing immunity and a preparation method thereof. The composition for relieving stress and enhancing immunity is calculated in parts by weight, 100-300 parts of a radix curcuma extract, 100-250 parts of a sea cucumber extract, 100-250 parts of a chlorella extract, 50-150 parts of a cranberry extract, 100-300 parts of a ginseng extract, 80-150 parts of a coconut oil extract and 100-200 parts of a palm oil extract. The composition can significantly enhance the body's immunity, relieve mental stress and improve the level of human health. In addition, the composition of the present invention is suitable for long-term use and has a small adverse reaction. 1. A composition for relieving stress and enhancing immunity , characterized in , the composition for relieving stress and enhancing immunity is calculated in parts by weight , 100-300 parts of a turmeric extract , 100-250 parts of a sea cucumber extract , 100-250 parts of a chlorella extract , 50-150 parts of a cranberry extract , 100-300 parts of a ginseng extract , 80-150 parts of a coconut oil extract , and 100-200 parts of a palm oil extract.2. The composition for relieving stress and enhancing immunity according to claim 1 , characterized in claim 1 , the composition for relieving stress and enhancing immunity is calculated in parts by weight claim 1 , further comprising 50-100 parts of lecithin and 50-80 parts of 5-hydroxytryptophan.3. The composition for relieving stress and enhancing immunity according to claim 1 , characterized in claim 1 , the composition for relieving stress and enhancing immunity is calculated in parts by weight claim 1 , 150-250 parts of a turmeric extract claim 1 , 100-200 parts of a sea cucumber extract claim 1 , 150-200 parts of a chlorella extract claim 1 , 80-100 parts of a cranberry extract claim 1 , 150-250 parts of a ginseng extract claim 1 , 100-150 ...

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09-01-2020 дата публикации

METHODS OF HEATING CANNABIS PLANT MATERIAL

Номер: US20200009109A1
Принадлежит:

The present invention includes a method of drying plant material generally comprising exposing the plant material to infrared radiation emitted from an infrared heater, such as a catalytic gas heater, the radiation having a wavelength of from about 3 to about 10 microns; and heating the plant material to a temperature of from about 100° F. to about 400° F. 1Cannabis. A method of drying a plant material comprising:{'i': 'Cannabis', 'exposing the plant material to infrared radiation emitted from an infrared heater, the radiation having a wavelength of from about 3 to about 10 microns; and'}{'i': 'Cannabis', 'heating the plant material to a temperature of from about 100° F. to about 400° F.'}2CannabisCannabis. The method of claim 1 , wherein the plant material is exposed to the infrared radiation for a period of time such that less than 25% of a cannabinoid compound in the plant material is decarboxylated.3. The method of claim 2 , wherein the cannabinoid compound comprises cannabidiolic acid (CBDA).4. The method of claim 2 , wherein the cannabinoid compound comprises tetrahydrocannabinolic acid (THCA).5Cannabis. The method of claim 1 , further including a step of circulating air over the plant material.6. The method of claim 1 , wherein the infrared heater is a catalytic gas heater operating at a gas pressure allowing heater output from 50% to 100% of rated power.7Cannabis. The method of claim 1 , wherein the method does not comprise actively controlling the humidity of the air around the plant material while being exposed to the infrared radiation.8Cannabis. The method of claim 1 , wherein the plant material does not exceed 180° F. during the heating step.9Cannabis. The method of claim 1 , wherein the heating step comprises removing at least 10% of the moisture content from the plant material.10CannabisCannabis. The method of claim 1 , wherein the plant material is exposed to the infrared radiation for a period of time such that more than 75% of a cannabinoid ...

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09-01-2020 дата публикации

METHOD FOR PREPARATION OF PHARMACOLOGICALLY-RELEVANT COMPOUNDS FROM BOTANICAL SOURCES

Номер: US20200009205A1
Автор: RIVAS Jose
Принадлежит:

In a multi-step process for selectively purifying various pharmacologically-relevant components of a source plant such as cannabis, an initial step of the process provides a low-temperature, robust essential oil/terpene capture that also dehydrates and decarboxylates the starting product—fresh raw cannabis—by means of a vacuum-assisted microwave distillation process. By doing the terpene capture under vacuum distillation temperature may be kept low. The low distillation temperature maximizes yields of thermally-sensitive components such as terpenes and cannabinoids. The process includes additional steps of: extract cannabinoids from the dehydrated cannabis to produce a crude extract via a supercritical CO2 extraction process; purify crude extract of fats, lipids, plant material; and distill relevant cannabinoids from the purified crude extract via a wiped-film process. Selected terpenes and cannabinoids are then recombined in predetermined proportions to achieve extracts of unusual purity and having targeted therapeutic profiles. 1. A method for preparing purified extracts from raw cannabis comprising:A. distilling a terpene-rich essential oil from a water/raw cannabis mixture prepared by heating the raw cannabis/water mixture under gravity-assisted, vacuum conditions in a microwave oven at a predetermined power level for a predetermined period of time;B. followed by preparing a cannabinoid-rich crude extract from dried, decarboxylated cannabis resulting from A by exposing the dried, decarboxylated cannabis to a solvent and allowing a resulting extract to accumulate in a collection vessel as the solvent is purged;C. followed by refining the crude extract to remove impurities; andD. followed by preparing a purified extract from the refined extract by distilling the refined extract in a wiped-film evaporator under vacuum conditions.2. The method of claim 1 , further comprising:recombining the terpene-rich essential oil and the purified extract in predetermined ...

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09-01-2020 дата публикации

METHOD FOR PREPARATION OF PHARMACOLOGICALLY-RELEVANT COMPOUNDS FROM BOTANICAL SOURCES

Номер: US20200009206A1
Автор: RIVAS Jose
Принадлежит:

In a multi-step process for selectively purifying various pharmacologically-relevant components of a source plant such as cannabis, an initial step of the process provides a low-temperature, robust essential oil/terpene capture that also dehydrates and decarboxylates the starting—fresh raw cannabis—by means of a vacuum-assisted microwave distillation process. By doing the terpene capture under vacuum distillation temperature may be kept low. The low distillation temperature maximizes yields of thermally-sensitive components such as terpenes and cannabinoids. The process includes additional steps of: extract cannabinoids from the dehydrated cannabis to produce a crude extract via a supercritical CO2 extraction process; purify crude extract of fats, lipids, plant material; and distill relevant cannabinoids from the purified crude extract via a wiped-film process. Selected terpenes and cannabinoids are then recombined in predetermined proportions to achieve extracts of unusual purity and having targeted therapeutic profiles. 1. A method for preparing purified extracts from raw cannabis comprising:A. distilling a terpene-rich essential oil from a water/raw cannabis mixture prepared by heating the raw cannabis/water mixture under gravity-assisted, vacuum conditions in a microwave oven at a predetermined power level for a predetermined period of time;B. followed by preparing a cannabinoid-rich crude extract from dried, decarboxylated cannabis resulting from A by exposing the dried, decarboxylated cannabis to a solvent and allowing a resulting extract to accumulate in a collection vessel as the solvent is purged;C. followed by refining the crude extract to remove impurities; andD. followed by preparing a purified extract from the refined extract by distilling the refined extract in a wiped-film evaporator under vacuum conditions.2. (canceled)3. The method of claim 1 , wherein A further comprises:heating a distillation vessel containing raw cannabis in a microwave oven ...

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09-01-2020 дата публикации

METHODS TO REDUCE FAT ACCUMULATION AND OXIDATIVE DAMAGE IN LIVER USING GREEN MANGO EXTRACTS AND COMPOUNDS OBTAINED THEREFROM

Номер: US20200009207A1
Принадлежит:

Provided is a method for reducing fat accumulation in and oxidative damage to liver cells by using a green mango extract. Also provided is a method for reducing fat accumulation in liver cells by using compounds of hydrolyzable tannins isolated from the green mango extract. 1. A method for reducing fat accumulation and oxidative damage to a liver cell , comprising the step of contacting the liver cell with a composition comprising an effective amount of a green mango extract , wherein the green mango extract is obtained by extraction of a green mango with a solvent; and the green mango is an unripe mango fruit with a length of 3 to 7 cm.2. The method of claim 1 , wherein the weight ratio of the solvent to the green mango ranges from 20:1 to 1:1.3. The method of claim 1 , wherein the extraction is performed at a temperature between 55° C. and 100° C.4. The method of claim 1 , wherein the solvent is water.5. The method of claim 1 , wherein the composition comprises at least 1 mg/mL of the green mango extract.6. The method of claim 1 , wherein the green mango extract reduces apoptosis of the liver cell.8. The method of claim 7 , wherein Ris p-hydroxybenzoyl.9. The method of claim 7 , wherein Ris galloyl.10. The method of claim 7 , wherein the compound represented by formula (I) is at a concentration of at least 10 μg/mL. This application claims priority of U.S. Provisional Application No. 62/694,497, filed on Jul. 6, 2018, and Taiwan patent application No. 108119809, filed on Jun. 19, 2019, the content of which is incorporated herein in its entirety by reference.The present invention relates to a method for health care by using a green mango extract and hydrolyzable tannins obtained therefrom. Particularly, the present invention relates to a method for reducing fat accumulation and oxidative damage in liver cells by using the green mango extract; and a method for reducing fat accumulation in liver cells by using the hydrolyzable tannins.The liver is a vital organ in ...

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03-02-2022 дата публикации

Method and Compositions for Treating Equine Encephalitis

Номер: US20220031784A1
Принадлежит: Phoenix Biotechnology Inc

A method of treating equine encephalitis is provided. A composition having at least one cardiac glycoside, such as oleandrin, is used to treat a viral infection causing the encephalitis. The composition can further include at least one triterpene. Alternatively, the composition comprises at least one, at least two, or at least three triterpenes.

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19-01-2017 дата публикации

HERBAL COMPOSITION FOR BODY TREATMENT

Номер: US20170014464A1
Принадлежит:

The present invention discloses an herbal composition comprising a therapeutic effective amount of Cascalote () and a therapeutic effective amount of Ruda (). In another implementation, the herbal composition can also comprise of an effective amount of at least one pharmaceutically acceptable excipient for application to the body, including skin and tissue. The disclosed invention also includes a method for making the herbal composition and a method of application of the herbal composition. 1. An herbal composition comprising:a therapeutic effective amount of Cascalote; anda therapeutic effective amount of Ruda.2. The herbal composition of claim 1 , further comprising:an effective amount of at least one pharmaceutically acceptable excipient.3. The herbal composition of claim 1 , wherein a range of therapeutic effective amount of Cascalote is made from 0.25-2 lbs. of Cascalote per one gallon of pharmaceutically acceptable excipient.4. The herbal composition of claim 1 , wherein a range of therapeutic effective amount of Ruda is made from 0.25-2 oz. of Ruda per one gallon of pharmaceutically acceptable excipient.5. The herbal composition of claim 2 , wherein the at least one pharmaceutically acceptable excipient is in a range of 90% to 98% w/w of the total composition of the herbal composition.6. The herbal composition of claim 2 , wherein the pharmaceutically acceptable excipient comprises at least one of astringent claim 2 , antioxidant claim 2 , vaginal conditioning agent claim 2 , vasodillating agent claim 2 , thickening agent claim 2 , preservative claim 2 , lubricating agent claim 2 , colorant claim 2 , and water.7. The herbal composition of claim 2 , wherein the pharmaceutically acceptable excipient may be an orally or topically acceptable carrier and/or an orally or topically acceptable diluent.8. The herbal composition of claim 1 , for the treatment of at least one of skin and tissue.9. The herbal composition of claim 1 , for the treatment of a ...

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26-01-2017 дата публикации

SYSTEMS AND METHODS FOR CANNABINOID AND TERPENE EXTRACTION AND PURIFICATION

Номер: US20170020944A1
Автор: Towle Tyrell R.
Принадлежит:

A method for preparing a purified extract may comprise extracting a crude extract from solids, dewatering the crude extract, removing chlorophyll from the crude extract, and distilling the crude extract thereby creating a purified extract. The extracting step may include contacting crude solids with an organic ester, thereby creating the crude extract and waste solids. The dewatering step may include contacting the crude extract with a solid dewatering agent and filtering the crude extract from the solid dewatering agent. The removing chlorophyll step may include contacting the crude extract with a solid absorbent agent, and filtering the crude extract from the solid absorbent agent. 1Cannabis. A method of preparing a purified extract , the method comprising: {'i': 'Cannabis', 'contacting crude solids with an organic ester, thereby creating e crude extract and waste solids;'}, '(a) extracting a crude extract, wherein the extracting comprises (i) contacting the crude extract with a solid dewatering agent; and', '(ii) filtering the crude extract from the solid dewatering agent;, '(b) dewatering the crude extract,wherein the dewatering comprises (i) contacting the crude extract with a solid absorbent agent; and', '(ii) filtering the crude extract from the solid absorbent agent;, '(c) removing chlorophyll From the crude extract,wherein the removing comprises{'i': 'Cannabis', '(d) distilling the crude extract to remove a majority of the organic ester, thereby creating the purified extract.'}2. The method of claim 1 , wherein the extracting step (a) comprises:heating the organic ester.3. The method of claim 2 , wherein the extracting step (a) comprises:refluxing the organic ester.4. The method of claim 3 , wherein the extracting step is performed in a soxhlet apparatus.5. The method of claim 2 , wherein the organic ester is heated to a temperature of 20 to 80 degrees Celsius.6. The method of claim 1 , wherein the extracting a crude extract step comprises:cooling the ...

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10-02-2022 дата публикации

COMPOSITIONS COMPRISING CBD FOR TREATING MENTAL DISORDERS

Номер: US20220040124A1
Принадлежит:

The present invention discloses compositions comprising CBD and several herbal extract and use thereof in treatment of mental disorders such as Attention Deficit Hyperactivity disorder (ADHD) and Post Traumatic Stress Disorder (PTSD). 116-. (canceled)17Bacopa monnieriCentella AsiaticaWithania Somnifera. A composition comprising from about 5 to about 22% by weight of CBD oil , from about 15 to about 40% by weight of extract , from about 15 to about 40% by weight of extract , and from about 15 to about 40% by weight of extract.18. The composition according to claim 17 , comprising from about 8 to about 20% by weight of CBD oil.19. The composition according to claim 17 , wherein said CBD oil comprises from about 55 to about 75% by weight of CBD.20. The composition according to claim 17 , wherein the CBD oil is obtained from plant extract claim 17 , or is synthetically prepared.21Bacopa monnieri. The composition according to claim 17 , comprising from about 25 to about 35% by weight of extract.22Centella Asiatica. The composition according to claim 17 , comprising from about 25 to about 35% weight of extract.23Withania Somnifera. The composition according to claim 17 , comprising from about 25 to about 35% by weight of extract.24Bacopa monnieriCentella AsiaticaWithania Somnifera. The composition according to claim 17 , comprising from about 8 to about 22% by weight of CBD oil claim 17 , from about 25 to about 35% by weight of extract claim 17 , from about 25 to about 35% by weight of extract claim 17 , and about from about 25 to about 35% by weight of extract.25. The composition according to claim 17 , wherein the composition further comprises an orally acceptable carrier.26. The composition according to claim 17 , wherein the composition is a pharmaceutical composition comprising one or more pharmaceutically acceptable excipients.27. The composition according to claim 17 , formulated for a systemic administration.28. The composition of claim 27 , wherein the systemic ...

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10-02-2022 дата публикации

LIQUID INVISIBLE MASK WITH BROAD-SPECTRUM BACTERIOSTASIS AND PREPARATION METHOD AND USING METHOD THEREOF

Номер: US20220040249A1
Принадлежит: Hunan Tianxiang Biotechnology Co., Ltd

A liquid invisible mask, and a preparation method and a using method thereof are provided by the present disclosure, and the present disclosure relates to the technical field of isolated bacteriostatic protective materials. The liquid invisible mask which is a film covering a surface of a nasal cavity, an oral cavity or a throat mucosa, wherein: the film comprises a garlic extract with garlicin content more than 45%, sesame essential oil and cream; and a mass ratio of the garlic extract, the sesame essential oil and the cream is (70-85):(10-20):(5-10). The present disclosure takes the garlic extract with high content of garlicin as the active component, ensures the basic efficacy of sterilization and toxicity elimination, and is supplemented with sesame essential oil as the film-forming carrier material and cream as the skeleton material. 1. A liquid invisible mask which is a film covering a surface of a nasal cavity , an oral cavity or a throat mucosa , wherein: the film comprises a garlic extract with garlicin content more than 45% , sesame essential oil and cream; and a mass ratio of the garlic extract , the sesame essential oil and the cream is (70-85):(10-20):(5-10).2. The liquid invisible mask according to claim 1 , wherein: content of the garlic extract is 70% to 85% of a total mass of the liquid invisible mask; content of the sesame essential oil is 10% to 20% of the total mass of the liquid invisible mask claim 1 , and content of the cream is 5% to 10% of the total mass of the liquid invisible mask.3. The liquid invisible mask according to claim 2 , wherein: a mass ratio of the garlic extract to the sesame essential oil is (80-85):(10-15).4. The liquid invisible mask according to claim 1 , wherein: a mass ratio of the sesame essential oil to the cream is (10-15):(5-10).5. The liquid invisible mask according to claim 1 , wherein: the mass ratio of the garlic extract claim 1 , the sesame essential oil and the cream is (80-85):(10-15):(5-10).6. The liquid ...

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24-01-2019 дата публикации

TOBACCO PRODUCTS WITH CANNABINOID ADDITIVES AND METHODS FOR REDUCING THE HARM ASSOCIATED WITH TOBACCO USE

Номер: US20190022158A1
Принадлежит: Vireo Health LLC

A substantially pure fraction of at least one cannabinoid is added to smokable or smokeless tobacco products to reduce the harm associated with tobacco use. The harm to be reduced includes irritation and carcinogenicity of tobacco. In a preferred embodiment a whole plant cannabis extract is mixed directly with the tobacco during the curing or manufacturing process. For cigarette applications the cannabinoids may be inserted into a cigarette filter, and/or paper. In other embodiments the cannabinoids are purified. 1. A method for reducing the harm associated with tobacco use comprising providing tobacco users with a tobacco product to which has been added at least one cannabinoid.2. The method of wherein the tobacco product is selected from the group consisting of cigarettes claim 1 , cigars claim 1 , chewing tobacco claim 1 , and moist snuff.3. The method of wherein the at least 1 added cannabinoid is selected from the group consisting of tetrahydrocannabinol (THC) claim 2 , cannabidiol (CBD) claim 2 , tetrahydrocannabinolic acid (THCA) claim 2 , Cannabidiolic acid (CBDA) claim 2 , cannabinol (CBN) claim 2 , cannabigerol (CBG) claim 2 , cannabichromene (CBC) claim 2 , tetrahydrocannabivarin (THCV) claim 2 , and cannabidivarin (CBDV).4. The method of wherein the at least one added cannabinoid is CBD5. The method of wherein the at least one cannabinoid is a combination of THC and CBD.6. The method of wherein the THC and CBD are present in a ratio of about 1:20 claim 5 , THC:CBD.7. The method of wherein the THC and CBD are present in a ration of about 1:1 claim 5 , THC to CBD.8. The method of wherein at least 1 added cannabinoid is in the form of a whole plant cannabis extract. N/AThe present invention relates to tobacco products such as cigarettes, cigars, pipe tobacco (bulk), roll your own, and smokeless tobacco products also known as “snuff,” “chewing tobacco,” and “dipping tobacco.” More particularly, novel forms of tobacco and tobacco products including, cured and ...

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31-01-2019 дата публикации

PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING

Номер: US20190030103A1
Автор: Speier Gary J.
Принадлежит:

The present invention provides for methods of obtaining an extract of plant material as well as subsequent processing of the extract to provide a concentrate of . The present invention also provides for pharmaceutical dosage forms (e.g., oral thin films and transdermal patches) that include the concentrate (or extract) of , as well as methods of medical treatment that include administering the pharmaceutical dosage forms. 1. (canceled)221-. (canceled)23cannabiscannabis. The method of claim 22 , wherein relative to the plant material claim 22 , the concentrate that is enriched with cannabigerolic acid (CBGA) contains at least about a 10% higher concentration of cannabigerolic acid (CBGA).24cannabiscannabis. The method of claim 22 , wherein relative to the plant material claim 22 , the concentrate that is enriched with cannabigerolic acid (CBGA) contains at least about a 20% higher concentration of cannabigerolic acid (CBGA).25. The method of claim 22 , wherein each one of the fractional supercritical fluid extractions is carried out in a solvent system that comprises carbon dioxide (CO).26. The method of claim 22 , wherein any one of the fractional supercritical fluid extractions is carried out in a solvent system that comprises carbon dioxide (CO) and optionally at least one of hydrogen (H) claim 22 , neon (Ne) claim 22 , nitrogen (N) claim 22 , argon (Ar) claim 22 , methane (CH) claim 22 , ethane (CHCH) claim 22 , propane (CHCHCH) claim 22 , ammonia (NH) claim 22 , water (HO) claim 22 , xenon (Xe) claim 22 , methanol claim 22 , ethanol claim 22 , 1-propanol claim 22 , 2-propanol claim 22 , 1-hexanol claim 22 , 2-methoxy ethanol claim 22 , tetrahydrofuran (THF) claim 22 , 1 claim 22 ,4-dioxane claim 22 , acetonitrile claim 22 , methylene chloride claim 22 , dichloroethane claim 22 , chloroform claim 22 , ethyl acetate claim 22 , propylene carbonate claim 22 , N claim 22 ,N-dimethylaceamide claim 22 , dimethyl sulfoxide (DMSO) claim 22 , formic acid claim 22 , carbon ...

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24-02-2022 дата публикации

PHARMACEUTICAL COMPOSITION COMPRISING EXTRACT FROM CAMELLIA JAPONICA AS ACTIVE INGREDIENT FOR PREVENTION AND TREATMENT OF VIRAL INFECTION

Номер: US20220054576A1
Автор: Joo Seong Soo
Принадлежит:

An aspect of the present invention provides a pharmaceutical composition containing extract derived from a natural substance as an active ingredient for prevention and treatment of viral infection, wherein the extract inhibits viral replication and release from cells to effectively regulate viral infection, thus exhibiting an excellent antiviral effect. 1Camellia japonicaCamellia japonica. A method for preventing , improving , or treating a viral infection in a subject , the method comprising administering to the subject a therapeutically effective amount of a extract or an active fraction separated by chromatography of the extract.2. The method of claim 1 , wherein the extract is obtained by extraction with water claim 1 , a Cto Clower alcohol claim 1 , or a mixture thereof.3. The method of claim 1 , wherein the active fraction is prepared by a preparative liquid chromatography process.4. The method of claim 1 , wherein the virus is a RNA virus.5. The method of claim 4 , wherein the RNA virus is a negative single-stranded RNA virus claim 4 , a positive single-stranded RNA virus claim 4 , or single stranded RNA reverse-transcribing virus.6. The method of claim 4 , wherein the RNA virus is a reovirus claim 4 , a picornavirus claim 4 , a calicivirus claim 4 , a togavirus claim 4 , an arenavirus claim 4 , a flavivirus claim 4 , an orthomyxovirus claim 4 , a paramyxovirus claim 4 , a bunyavirus claim 4 , a rhabdovirus claim 4 , a filovirus claim 4 , a coronavirus claim 4 , an astrovirus claim 4 , a bornavirus claim 4 , a retrovirus or an arterivirus.7. The method of claim 6 , wherein the orthomyxovirus is an influenza A virus claim 6 , an influenza B virus claim 6 , an influenza C virus claim 6 , influenza D virus claim 6 , an isavirus claim 6 , a thogotovirus claim 6 , or a quaranjavirus.8. The method of claim 6 , wherein the coronavirus is SARS coronavirus claim 6 , MERS coronavirus claim 6 , or novel coronavirus (SARS-CoV-2).9Camellia japonicaCamellia japonica. A ...

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07-02-2019 дата публикации

Method for conversion and extraction of beneficial components in ginseng

Номер: US20190038691A1
Автор: Ken Lee
Принадлежит: Egeonhoco ltd, EgeonjoCo ltd

Provided is a method for conversion and extraction of beneficial components, the method including: a vacuum step for feeding ginseng into a vacuum chamber and applying a vacuum pressure thereinto; and a treatment step for heating and drying the ginseng under the vacuum pressure, so that the loss of beneficial components can be minimized and the treatment cost can be lowered by simplifying the treatment procedure and shortening the treatment time, and the saponin conversion and extraction efficiencies can be effectively increased through a simple treatment procedure.

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15-02-2018 дата публикации

METHOD OF TREATING PHOTO-INDUCED OCULAR FATIGUE AND ASSOCIATED REDUCTION IN SPEED OF OCULAR FOCUS

Номер: US20180042978A1
Принадлежит:

A method of treating photo-induced ocular fatigue and associated reduction in speed of ocular focus in humans includes administering a therapeutic amount of a dietary supplement composition comprising a carrier admixed with carotenoids, which may include 0.5 to 8.0 mg of astaxanthin, 2.0 to 15 mg of lutein and 0.2 to 12.0 mg of zeaxanthin. The composition is formulated into an oral dosage form as a single dosage capsule. 1. A method of treating photo-induced ocular fatigue and associated reduction in speed of ocular focus in humans , which comprises administering a therapeutic amount of a dietary supplement composition comprising a carrier admixed with carotenoids consisting of 0.5 to 8.0 mg of astaxanthin , 2.0 to 15 mg of lutein and 0.2 to 12.0 mg of zeaxanthin , and wherein the composition is formulated into an oral dosage form as a single dosage capsule.2. The method according to wherein said carrier comprises at least one of a lipid and a fatty acid.3. The method according to wherein said lipid comprises phospholipids that are 5% to 60% by weight of the composition.4. The method according to wherein said phospholipids comprise seed based phospholipids.5. The method according to wherein said phospholipids comprise phospholipids derived from a marine source.6. The method according to further comprising a seed oil containing phospholipid bound EPA and DHA.7. The method according to wherein said fatty acid comprises an omega-3 fatty acid.8Haematococcus pluvialis. The method according to wherein the carotenoids consist of 4.0 to 6.0 mg of astaxanthin derived from (Hp) claim 2 , 10 to 12 mg of lutein and 1.0 to 2.5 mg of zeaxanthin.9Haematococcus pluvialis. A method of treating photo-induced ocular fatigue and associated reduction in speed of ocular focus in humans claim 2 , which comprises administering a therapeutic amount of a dietary supplement composition comprising 50 to 700 mg of a carrier claim 2 , including at least one of a lipid and a fatty acid and ...

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03-03-2022 дата публикации

METHOD FOR TREATING GLIOBLASTOMA MULTIFORME

Номер: US20220062363A1
Принадлежит:

The present invention relates to a method for treating glioblastoma multiforme including administering a Chinese medicine composition to a subject in need thereof; wherein the Chinese medicine composition is an extract of a first mixture including and 1. A method for treating glioblastoma multiforme , comprising:{'i': Boswella sacra, Commiphora molmol, Angelica sinensis, Ligusticum striatum, Rehmannia glutinosa, Paeonia veitchii, Prunus persica', 'Carthamus tinctorius., 'administering a Chinese medicine composition to a subject in need thereof; wherein the Chinese medicine composition is an extract of a first mixture comprising , and'}2. The method of claim 1 , wherein the Chinese medicine composition is prepared by the following steps:providing the first mixture;mixing the first mixture with water to form a second mixture;heating the second mixture to obtain a crude extract; andfiltering the crude extract to keep a liquid extract and obtain the Chinese medicine composition.3Boswella sacra,Commiphora molmol,Angelica sinensis,Ligusticum striatum,Rehmannia glutinosa,Paeonia veitchii,Prunus persicaCarthamus tinctorius.. The method of claim 1 , wherein the first mixture comprises 2-10 parts by weight of 2-10 parts by weight of 2-4 parts by weight of 2-4 parts by weight of 2-4 parts by weight of 2-4 parts by weight of 2-4 parts by weight of claim 1 , and 1-3 parts by weight of4. The method of claim 3 , wherein the part by weight of the first mixture is 2.5-5 gram per part.5Dipsacus asperoides, Davallia mariesii, Achyranthes bidentate, Scutellaria baicalensis, Coptis teeta, Phellodendron amurense, Poria cocos, Alisma plantagoaquatic, Polyporus umbellatus, Atractylodes lancea, Gastrodia elata, Tetradium ruticarpum, Ephedra sinica, Notopterygium incisium, Bupleurum falcatum, Citri Reticulatae Pericarpium, Anredera cordifolia, Panax ginseng, Aconitum carmichaeli, Pimenta officinalis, Morus albaGlycyrrhiza uralensis.. The method of claim 1 , wherein the first mixture further ...

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03-03-2022 дата публикации

METHOD AND COMPOSITIONS FOR THE USE OF BOTANICAL EXTRACTS IN THE TREATMENT OF VIRAL INFECTIONS

Номер: US20220062365A1
Принадлежит:

The present disclosure relates generally to the preparation and use of certain botanical extracts and therapeutic compositions for the treatment of viral infections, cancer, pain, itch, and inflammation. The present disclosure generally relates to antiviral compositions, and more specifically to the preparation of botanical extracts and their use in the treatment of viral infections, cancer, pain associated conditions. 1Sarracenia, Nepenthes, Melissa, Lavandula, Glycyrrhiza, Eleutherococcus, Hypericum, Darlingtonia, Heliamphora, Roridula, Drosera, Dionaea, Aldrovanda, Drosophyllum, Triphyophyllum, Catopsis, Brocchinia, Paepalanthus, Utricularia, Genlisea, Pinguicula, Ibicella, Byblis, Philcoxia, StylidiumCephalotus. A method for inhibiting the replication of a poxvirus by exposing the poxvirus to an extract from a plant material chosen from and , wherein the plant material is prepared by steps comprising:obtaining fresh plant material less than about ten (10) days following harvest of the plant material;washing and air drying the plant material;combining the plant material with a liquid comprising at least one of water, ethanol, and glycerol;allowing the liquid to extract the plant material at a temperature between about room temperature and simmering for about one (1) to about sixty (60) days, or by boiling for less than about one day to form the liquid extract; andseparating the liquid extract from the plant material.2. The method of claim 1 , wherein the plant material consists of leaves.3. The method of claim 1 , wherein the plant material consists of roots.4. The method of claim 1 , wherein the plant material comprises leaves and roots.5. The method of claim 1 , wherein the poxvirus is selected from the group consisting of orthopoxvirus claim 1 , parpoxvirus claim 1 , avipoxvirus claim 1 , capripoxvirus claim 1 , leporipoxvirus claim 1 , suipoxvirus claim 1 , molluscipox virus claim 1 , and yatapox virus.6. The method of claim 1 , wherein the poxvirus is a ...

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13-02-2020 дата публикации

Method and composition for treating eating disorders

Номер: US20200046722A1
Автор: Ramachandra MUKUNDA
Принадлежит: India Globalization Capital Inc

Method and composition for treating eating disorders in humans and veterinary animals by administering a composition including: (i) mirtazapine, (ii) a cannabis compound and (iii) a fat-soluble vitamin.

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13-02-2020 дата публикации

METHOD FOR OBTAINING OLIVE OIL AND AT LEAST ONE EXTRACT CONCENTRATED IN POLYPHENOLS AND A FUNCTIONAL INGREDIENT

Номер: US20200046791A1
Автор: MATEO ANSÓN Nuria
Принадлежит: ISANATUR SPAIN S.L.

A method comprising the stages of: olive input, separation of the stone from the olive skin and pulp, with the removal of the whole stone; electric pulsing of the olive paste generated in the previous stage, process of dehydration of the pulsed olive paste up to a humidity of less than 30% in a continuous vacuum drying machine and subsequent separation of the oil by centrifugation of the olive oil, followed by dehydration of the degreased pulp up to a humidity of less than 10%; and lastly, application of supercritical fluids (CO2 with or without modifier) to the degreased and dehydrated pulp, under agitation, pressure, temperature and time conditions, obtaining olive extracts and olive flour. The generation of waste, consumption of water, use of highly toxic solvents and loss of the sensory quality of the oil is avoided, the yields improved and the necessary times reduced. 1. A method for obtaining olive oil and at least one polyphenol concentrated extract and a functional ingredient characterised in that it comprises the stages of:{'b': 2', '3, 'Separating () the stone and skin from the olive pulp, obtaining the whole stone () on the one hand and, on the other, an olive paste;'}{'b': '4', 'Electric pulsing () of the olive paste with an electric field voltage of 1-3 kV/cm, frequency of 114-255 Hz and 2-10 pulses of 50-90 microseconds;'}{'b': '5', 'Dehydrating () the pulsed olive paste up to a humidity of <30% in a continuous vacuum drying machine under the following conditions: vacuum (<80 mbar of absolute pressure), temperature (<41° C.) and time (20-100 kg of evaporated water/h) or other conditions that preserve the thermolabile compounds of interest;'}{'b': 6', '7, 'Separating () the oil from the olive paste by centrifugation in a decanter with the necessary adjustments to treat de-stoned dehydrated pulp and obtainment of virgin olive oil ();'}{'b': '8', 'Dehydrating () the degreased pulp, after separating the oil, up to a humidity of less than 10% applying ...

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23-02-2017 дата публикации

COMPOSITIONS CONTAINING EXTRACTS OF CURCUMA LONGA AND ECHINACEA ANGUSTIFOLIA WHICH ARE USEFUL TO REDUCE PERIPHERAL INFLAMMATION AND PAIN

Номер: US20170049840A1
Автор: Bombardelli Ezio
Принадлежит:

The present invention relates to compositions containing, as their only active ingredients, an extract of spp, optionally as curcumin in the form of a complex with phospholipids, and an extract selected from spp extract or lipophilic extract of spp, which are useful in the topical and systemic treatment of peripheral pain and of superficial and deep inflammatory and painful conditions. The compositions according to the invention are particularly effective in the treatment of osteoarthritis and rheumatoid arthritis in patients unable to tolerate long-term treatment with NSAIDs or steroids. 1CurcumaEchinacea angustifoliaZanthoxylum bungeanum. Compositions substantially consisting of a spp extract or curcumin , and an extract selected from an extract or a lipophilic extract , mixed with acceptable excipients.2. Compositions according to wherein curcumin is complexed with phospholipids.3Echinacea angustifoliaZanthoxylum bungeanum. Compositions according to wherein the and extracts are prepared by extraction with supercritical carbon dioxide.4. Compositions according to claim 1 , for oral administration.5EchinaceaZanthoxylum. Compositions according to claim 4 , containing as the only active ingredients curcumin complexed with phospholipids in amounts ranging from 100 to 1000 mg claim 4 , and an extract in amounts ranging from 1 to 20 mg claim 4 , or alternatively a spp. lipophilic extract in amounts ranging from 5 to 25 mg per oral unit dose.6EchinaceaZanthoxylum. Compositions according to claim 5 , containing as the only active ingredients 500 mg of curcumin complexed with phospholipids claim 5 , and 5 mg of an extract claim 5 , or alternatively 10 mg of spp. lipophilic extract claim 5 , per oral unit dose.7. Compositions according to claim 1 , for topical administration.8EchinaceaZanthoxylum. Compositions according to claim 7 , containing curcumin complexed with phospholipids in amounts ranging from 0.1% to 0.5% w/w claim 7 , and an extract in amounts ranging from 0.05 ...

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20-02-2020 дата публикации

SYSTEMS AND METHODS OF CANNABIS OIL EXTRACTION

Номер: US20200054962A1
Принадлежит: Evello International, LLC

A oil extraction method includes performing grinding assisted extraction in the presence of solvent, co-solvent extraction with subcritical COcomprising, degassing the COand separating the mixture by centrifugation. 1cannabis. A oil extraction method , the method comprising: 'grinding plant material in the presence of solvent;', 'performing grinding assisted extraction comprising{'sub': '2', 'claim-text': {'sub': 2', '2, 'adding liquid COto the mixture, wherein the mixture is maintained at a temperature and pressure combination sufficient to maintain the liquid COin a subcritical state;'}, 'performing co-solvent extraction using subcritical COcomprising{'sub': '2', 'degassing the CO; and'}separating the mixture by centrifugation.2. The method of claim 1 , wherein the plant material ground in the presence of the solvent is wet plant material.3. The method of claim 1 , wherein a ratio of solvent to plant material present during the grinding assisted extraction is greater than 1:1 on a weight basis.4. The method of claim 1 , wherein a ratio of solvent to plant material present during the grinding assisted extraction is greater than 2:1 on a weight basis.5. The method of claim 1 , wherein grinding the plant material in the presence of solvent comprises grinding the plant material to micron scale.6. The method of claim 5 , wherein the plant material is ground to less than 20 microns during grinding assisted extraction.7. The method of claim 1 , wherein the solvent is a food grade solvent.8. The method of claim 1 , wherein the solvent is a non-polar solvent.9. The method of claim 8 , wherein the non-polar solvent is selected from pentane claim 8 , hexane claim 8 , benzene claim 8 , toluene claim 8 , carbon tetrachloride claim 8 , benzene claim 8 , glycerol monooleate claim 8 , diethyl ether claim 8 , hexane claim 8 , methylene chloride claim 8 , carbon dioxide claim 8 , methane claim 8 , ethylene claim 8 , D-limonene claim 8 , olive oil claim 8 , soybean oil claim 8 , ...

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17-03-2022 дата публикации

PROCESS OF OBTAINING ENRICHED FRACTIONS OF ASSETS FROM THE ARTEMISIA GENUS, ENRICHED FRACTIONS AND BIOACTIVE COMPOSITION

Номер: US20220080012A1
Принадлежит:

A process for obtaining enriched fractions of assets from the genus , enriched fractions obtained by the process and bioactive composition having fraction enriched from . The process uses extraction with supercritical fluid in which the differential consists of sequential extraction, in an unprecedented association of specific conditions and steps with an advantageous effect not previously found, thus obtaining enriched fractions of bioactives with different chemical compositions for a given application. The enriched fractions of assets of the genus and/or its so-called bioactive compositions having fraction enriched from obtained have application mainly in the pharmaceutical and cosmetic fields. 2Artemisiaannua, dracunculus, vulgaris, abysinica, absynthicum, aftra, cannariensis, scoparia. The process according to claim 1 , wherein a plant raw material belonging to the genus is selected from the group consisting of the species and combinations thereof.3Artemisia annua.. The process according to claim 2 , wherein the raw material is4. The process according to claim 1 , wherein in step a) the S/F ratio is 4 claim 1 , in step b) the S/F ratio is 4.3 and in step c) the S/F ratio is 27.5. The process according to claim 1 , wherein step a) is carried out at the temperature of 60° C. claim 1 , the pressure of 100 bar and the S/F ratio of 4.6. The process according to claim 1 , wherein step b) is carried out at the temperature of 50° C. claim 1 , the pressure of 300 bar and the S/F ratio of 4.3.7. The process according to claim 1 , wherein step c) is carried out at the temperature of 50° C. claim 1 , the pressure of 300 bar and the S/F ratio of 27.8. An enriched fraction obtained by the process according to comprising high artemisinin content for application in cosmetics and drugs.9. A bioactive composition comprising the second enriched fraction claim 1 , obtained by the process according to claim 1 , wherein the bioactive composition is rich in artemisinin for application ...

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17-03-2022 дата публикации

MANGOSTEEN PERICARP EXTRACT AND PROCESS FOR ITS PREPARATION THEREOF

Номер: US20220080014A1
Принадлежит:

The present invention discloses a mangosteen pericarp extract and process for its preparation thereof. The mangosteen pericarp extract containing α-mangostin and γ-mangostin which obtains from preparation steps comprising fragmentation, organic solvent soaking, aqueous solution, or acidic solution soaking, concentration, spray drying and grinding steps from the rind of the mangosteen. The present invention has advantages of simple preparation process to address efficiency issue, no need to have heating under reflux in extraction steps and the solvents which used are friendly to human body and environment. 1. A process for preparing a mangosteen pericarp extract , said process comprising the following steps:drying and fragmenting the mangosteen pericarp to obtain fragment of mangosteen pericarp;soaking the fragment of mangosteen pericarp in organic solvent with a concentration of at least 70% and placing it at room temperature, and filtering it to obtain a mangosteen pericarp organic solvent extract, wherein the ratio of the weight to volume of the fragment of mangosteen pericarp and the organic solvent is 1:2 to 1:20;soaking and heating the fragment of mangosteen pericarp obtained from the previous step in aqueous solution and placing it at room temperature, and filtering it to obtain a mangosteen pericarp aqueous extract and a mangosteen pericarp residue, wherein the ratio of the weight to volume of the fragment of mangosteen pericarp and the aqueous solution is 1:10 to 1:20;concentrating the mangosteen pericarp organic solvent extract and the mangosteen pericarp aqueous extract to obtain a mangosteen pericarp organic solvent concentrate and a mangosteen pericarp aqueous concentrate; andspray drying the mangosteen pericarp organic solvent concentrate to obtain a α-Xones Extract, wherein the α-Xones Extract containing 10% to 30% of xanthone.2. The process defined in claim 1 , wherein said process further comprising the following steps:adding a first specific amount ...

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27-02-2020 дата публикации

METHOD FOR PREPARING CURCUMA XANTHORRHIZA ROXB. EXTRACT

Номер: US20200061146A1
Принадлежит:

The present invention relates to a method for preparing a Roxb. extract. Further, the present invention provides a method for preparing a Roxb. extract comprising the following steps of: subjecting Roxb. to supercritical extraction to obtain an extract containing xanthorrhizol as an active ingredient; subjecting the supercritical extraction residue to ethanol extraction or supercritical extraction to obtain an extract containing curcumin as an active ingredient; subjecting the ethanol extraction or supercritical extraction residue to enzyme treatment to obtain immune polysaccharides having average molecular weight 33,000 Da; and obtaining a insoluble dietary fiber from the enzyme treatment residue, an extract containing xanthorrhizol, curcumin, immune polysaccharides and insoluble dietary fiber obtained by the said preparing method, and general food, health functional food, cosmetic, pharmaceutical compositions and the like containing the extracts as an active ingredient. Since the Roxb. extraction method according to the present invention can obtain various kinds of natural extracts from one raw material by applying a variety of extraction methods, the method can be very useful for the production of extracts using natural products. 1Curcuma xanthorrhiza. A method for preparing a Roxb. extract comprising the following steps of:{'i': 'Curcuma xanthorrhiza', 'sup': 'st', '1) subjecting Roxb. to supercritical extraction to prepare the 1extract;'}{'sup': st', 'nd, '2) subjecting a residue of the 1extract to ethanol extraction or supercritical extraction to prepare the 2extract;'}{'sup': nd', 'rd, '3) subjecting a residue of the 2extract to enzyme treatment to prepare the 3extract; and'}4) obtaining a residue containing insoluble dietary fiber.2Curcuma xanthorrhiza. The method for preparing a Roxb. extract according to claim 1 , wherein the supercritical extraction of the step 1) and step 2) is conducted using carbon dioxide or pentane as a supercritical fluid at a ...

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24-03-2022 дата публикации

Cannabinoid Compositions

Номер: US20220087972A9
Автор: Silver Ronald
Принадлежит: SRE Wellness, Inc.

A cannabinoid composition including a cannabinoid oil, such as THC oil or CBD oil, one or more thickeners such as gums, and a compound that forms an inclusion complex with the cannabinoid oil. The composition may include water, and in intermediate stages can include an alcohol. The composition can also include a sweetener to make it a sugar or a syrup. In some embodiments there are no other oils in the composition. 1. A cannabinoid infused ingestible composition comprising:a cannabinoid oil;a compound that forms an inclusion complex with the cannabinoid oil; anda thickener;wherein the cannabinoid oil is the only oil in the composition.2. The composition of further comprising a sweetener.3. The composition of wherein the sweetener is selected from the group consisting of white sugar claim 2 , cane sugar claim 2 , raw sugar claim 2 , fructose claim 2 , turbinado sugar claim 2 , coconut sugar claim 2 , date sugar claim 2 , stevia claim 2 , liquid stevia claim 2 , liquid sugar claim 2 , powdered sugar claim 2 , brown sugar claim 2 , muscovado sugar claim 2 , maple sugar claim 2 , honey claim 2 , and agave.4. The composition of wherein the compound comprises cyclodextrin.5. The composition of wherein the thickener comprises a gum.6. The composition of wherein the gum comprises xanthan gum.7. The composition of wherein the cannabinoid comprises tetrahydrocannabinol (THC) and/or cannabidiol (CBD).8. The composition of wherein the cannabinoid is bio-available claim 1 , highly metabolizable and fast acting when ingested.9. The composition of wherein the compound and the thickener each comprise 0.12% to 2% of the composition.10. The composition of comprising 0.01% to 4% of both the compound and the thickener.11. The composition of comprising 0.15% to 3% of both the compound and the thickener.12. The composition of comprising equal percentages of the compound and the thickener.13. A cannabinoid infused composition consisting essentially of:a cannabinoid oil;an alcohol;water;a ...

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15-03-2018 дата публикации

MEDICAL CANNABIS LOZENGES AND COMPOSITIONS THEREOF

Номер: US20180071350A1
Автор: KOLSKY JEFFREY A.
Принадлежит:

A method for optimizing the therapeutic effects provided by CBD on the one hand, and the psychoactive effects provided by THC on the other hand, in a sublingual medicament, the method includes the steps of obtaining a concentrated extract of in which the concentration of CBD is known and the concentration of THC is known, formulating a hydrophilic mixture containing ingredients such as sugar, corn syrup, xylitol, purified water, organic flavorings, coconut oil, and concentrated extract of , wherein the amount of CBD is as high as possible and where the amount of THC is precisely controlled, forming lozenges, and administering the medicament. 1cannabis sativacannabis. A lozenge consisting essentially of extracted oil , extracted indica oil , and xylitol.2. The lozenge of having a mass of between 2 grams and 15 grams.3. The lozenge of containing a minimum of 25 mg of CBD.4. The lozenge of containing a maximum of 40 mg of THC.5. The lozenge of containing a minimum of between about 0.1667% by weight and about 1.25% by weight of cannabidiol.6. The lozenge of containing a maximum of between about 0.2667% by weight and about 2.00% by weight of tetrahydrocannabinol7. The lozenge of further consisting essentially of an ingredient selected from the group consisting of sugar claim 1 , corn syrup claim 1 , flavorings claim 1 , coloring agents claim 1 , coconut oil claim 1 , purified water and mixtures thereof.8. A method for minimizing the psychoactive effects of THC in a human which is administered a sublingual lozenge claim 1 , the method consisting essentially of: a) formulating the lozenge of ; and b) administering the lozenge of sublingually to a human until the lozenge is dissolved in the human.9. The method of claim 8 , wherein the step of formulating the lozenge is maximizing the CBD concentration.10. The method of claim 8 , wherein the step of formulating the lozenge is minimizing the THC concentration.11. The method of claim 8 , wherein the step of formulating the ...

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24-03-2022 дата публикации

Composition comprising cudrania tricuspidate as effective component for alleviating, treating, or preventing muscular diseases, or improving muscule functions

Номер: US20220088106A1
Принадлежит: Att Costech Co Ltd

The present disclosure relates to a composition for preventing and treating a muscular disease, or improving muscular function, which contains Cudrania tricuspidata such as a pulverization product or an extract of Cudrania tricuspidata as an active ingredient. The Cudrania tricuspidata according to the present disclosure such as the pulverization product or extract of Cudrania tricuspidata has an effect of increasing the activity of mTOR, which is involved in muscle protein synthesis, and reducing the mRNA expression of MuRF-1 and atrogin-1, which are involved in muscle protein degradation, increases muscle mass and improves muscular function. Therefore, it may be usefully utilized in the prevention, alleviation or treatment of various muscular diseases such as atony, muscular atrophy, muscular dystrophy, muscle degeneration, muscle weakness, cachexia, sarcopenia, etc.

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07-03-2019 дата публикации

Traditional chinese medicine composition and use thereof

Номер: US20190070236A1
Принадлежит: Infinitus China Co Ltd

The present disclosure relates to the field of drugs and health foods. Disclosed is a traditional Chinese medicine composition comprising GANODERMA polysaccharide, MORINDAE OFFICINALIS RADIX polysaccharide, POLYGONATI RHIZOMA polysaccharide, ANGELICAE SINENSIS RADIX oil and MYRISTICAE SEMEN oil. Experiments show that the traditional Chinese medicine composition has a scientific formulation, synergistic functions, without toxic and side effects, and not only has nutritional value but also inhibits the growth of tumor. Comparing with individual components, the composition significantly increases the percentages of CD4 + and CD8 + cells in lymphocytes of the tumor stroma, enhances body immune function, restores normal immune surveillance function, decreases VEGF and TGF-β1 positive cells in tumor tissue, assists in treating tumor, increases antitumor effects of chemotherapy drugs, improves immune status of body, has the function of restoring normal immune surveillance, preventing and assisting in treating tumor.

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07-03-2019 дата публикации

TRADITIONAL CHINESE MEDICINE COMPOSITION AND USE THEREOF

Номер: US20190070246A1
Принадлежит: INFINITUS (CHINA) COMPANY LTD.

The present disclosure relates to the field of drugs and health foods. Disclosed is a traditional Chinese medicine composition comprising polysaccharide, polysaccharide, oil and oil. Experiments show that the traditional Chinese medicine composition has a scientific formulation, synergistic functions, without toxic and side effects, and not only has nutritional value but also inhibits the growth of tumor. Comparing with individual components, the composition significantly increases the percentages of CD4 and CD8 cells in lymphocytes of the tumor stroma, increases body immune function, recovers normal immune surveillance function, decreases the expression rate of VEGF and TGF-β 1 positive cells in tumor tissue, assists in treating tumor, increases antitumor effects of chemotherapy drugs, improves immune status of body, has the function of restoring normal immune surveillance, preventing and assisting in treating tumor. 1LYCII FRUCTUSPOLYGONATI RHIZOMACARYOPHYLLI FLOSCINNAMOMI CORTEX. A traditional Chinese medicine composition , comprising polysaccharide , polysaccharide , oil and oil.2LYCII FRUCTUSPOLYGONATI RHIZOMACARYOPHYLLI FLOSCINNAMOMI CORTEX. The tradition Chinese medicine composition according to claim 1 , wherein the weight ratio of polysaccharide claim 1 , polysaccharide claim 1 , oil and oil is (1 to 5):(1 to 5):(1 to 5):(1 to 5).3LYCII FRUCTUSPOLYGONATI RHIZOMACARYOPHYLLI FLOSCINNAMOMI CORTEX. The tradition Chinese medicine composition according to claim 1 , wherein the weight ratio of polysaccharide claim 1 , polysaccharide claim 1 , oil and oil is (1 to 2):(1 to 2):(1 to 2):(1 to 2).4LYCII FRUCTUSPOLYGONATI RHIZOMACARYOPHYLLI FLOSCINNAMOMI CORTEX. The tradition Chinese medicine composition according to claim 1 , wherein the weight ratio of polysaccharide claim 1 , polysaccharide claim 1 , oil and oil is 1:1:1.5:1.5.5. The tradition Chinese medicine composition according to claim 1 , which is in the form of a health food or a medicine.6. The tradition ...

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16-03-2017 дата публикации

METHOD AND SYSTEM FOR EXTRACTING COMPOUNDS FROM PLANTS AND PLANT BASED MATERIALS

Номер: US20170071992A1
Автор: TOMASO Paul
Принадлежит:

The invention provides a method and system for extracting desired compounds from a plant or a plant based material featuring a) providing a plant or plant based material; b) pumping COgas from a COstorage vessel into an apparatus containing a COcirculation loop; c) circulating COthrough the plant or plant based material in the circulation loop; d) extracting the desired compounds; and e) discharging the COgas from the COcirculation loop. The circulation loop may have a separator vessel and an extractor vessel, the desired compound may be a terpene, tetrahydrocannabinol (THC) or carbenoxolone (CBx), and the COmay be circulated as a supercritical CO. The invention also provides a system for extracting a desired compound from a plant or a plant based material featuring a) an extractor vessel; b) a separator vessel; c) a liquid accumulator; d) at least one hot water valve; e) at least one cold water valve; f) a gas pump; g) a liquid pump; h) at least one two-way valve; i) a three-way valve; and j) a COstorage vessel. 1. A method for extracting a desired compound from a plant or a plant based material comprising:a) providing a plant or plant based material;{'sub': 2', '2', '2, 'b) pumping COgas from a COstorage vessel into an apparatus containing a COcirculation loop;'}{'sub': '2', 'c) circulating COthrough the plant or plant based material in the circulation loop;'}d) extracting the desired compound; and{'sub': 2', '2, 'e) discharging the COgas from the COcirculation loop.'}2. The method of wherein the COcirculation loop comprises a separator vessel and an extractor vessel.3. The method of wherein the desired compound is selected from the group consisting of a terpene claim 1 , tetrahydrocannabinol (THC) and carbenoxolone (CBx).4. The method of wherein the COis circulated as a supercritical CO.5. The method of wherein the c) circulating the COthrough the plant or plant based material in the circulation loop lasts for a predetermined amount of time set by a control ...

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05-03-2020 дата публикации

PROCESS FOR PREPARATION OF CO2 EXTRACT OF AZADIRACHTA INDICA AND HERBAL COMPOSITIONS THEREOF FOR TREATMENT OF CANCERS

Номер: US20200069636A1
Автор: SOMAN Girish Sudhakar
Принадлежит:

The present invention discloses process for preparation of a COextract of and herbal compositions thereof for the treatment of Oral and Colon cancers. More particularly, the invention discloses a process for preparation of a standardized SCOextract of leaves and herbal compositions of the same for oral use. 1Azadirachta indica. A process for preparation of a COextract of leaves , comprising{'i': 'Azadirachta indica', 'a) powdering dried leaves having a moisture content of less than 12% to obtain a powder comprising particles having a size of less than 0.42 mm;'}{'sub': 2', '2', '2, 'b) subjecting the powder of step a) to extraction with supercritical COat a pressure ranging from 80 Bar (80 kg/cm) to 350 Bar (350 kg/cm) at a temperature ranging from 31° C. to 45° C. to obtain a COcomposition comprising COextractives and a residual powder,'}{'sub': 2', '2, 'c) separating the COextractives from the COcomposition at a pressure ranging from 40 Bar to 65 Bar at a temperature lower than the extraction temperature to obtain an Extract A;'}{'sub': 2', '2, 'i': 'Azadirachta indica', 'd) subjecting the residual powder to further extraction using a mixture of COand ethyl alcohol at a pressure ranging between 80 Bar to 350 Bar and at an extraction temperature ranging from 31° C. to 45° C. to obtain an ethyl alcohol/COcomposition comprising extractives;'}{'i': 'Azadirachta indica', 'sub': '2', 'claim-text': reducing a solvent pressure to between 40 Bar and 65 Bar at a temperature lower than the extraction temperature, followed by', 'vacuum distillation of the ethyl alcohol; and, 'e) recovering the extractives from the ethyl alcohol/COcomposition as an Extract B by{'sub': '2', 'i': 'Azadirachta indica', 'f) combining the Extract A and the Extract B to obtain the COextract of leaves.'}2. The process as claimed in claim 1 , wherein subjecting the powder of step a) to supercritical COextraction is carried out at a flow rate of 10 to 40 kg of COper kg of raw material.3. The process as ...

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22-03-2018 дата публикации

CHINESE MEDICINE EXTRACT AND PREPARATION METHOD AND APPLICATION THEREOF

Номер: US20180078584A1
Принадлежит: INFINITUS (CHINA) COMPANY LTD.

A Chinese medicine extract and preparation method and application thereof. Raw materials of the extract are and propolis. The extract has an excellent effect of inhibiting CaN-NF-AT pathway and a lower relative toxicity for cells. 1Artemisia carvifolia. A Chinese medicine extract which is prepared from and propolis.2Artemisia carvifolia. The Chinese medicine extract according to claim 1 , wherein the mass ratio of to propolis is 3:5 to 5:3.3Artemisia carvifolia. A method for preparing the Chinese medicine extract according to claim 1 , comprising extracting and propolis.4. The method according to claim 3 , wherein a solvent for extraction is one of the group consisting of alcohols claim 3 , alkanes claim 3 , chloroform claim 3 , acetone claim 3 , water and ethyl acetate claim 3 , or a mixture thereof.5. The method according to claim 3 , wherein the extraction method is percolation claim 3 , impregnation claim 3 , decoction claim 3 , reflux extraction claim 3 , continuous reflux extraction claim 3 , supercritical fluid extraction or ultrasound extraction.6. A method for inhibiting CaN-NF-AT pathway claim 1 , treating skin inflammations claim 1 , treating autoimmune diseases claim 1 , skin relax or anti-allergy in a subject in need thereof comprising administering to the subject a therapeutically effective amount of the Chinese medicine extract of .7. (canceled)8. A medicament for treating skin inflammations or autoimmune diseases or a cosmetic for skin relax and anti-allergy claim 1 , comprising the Chinese medicine extract of .910-. (canceled) The present application claims the priority of Chinese Patent Application No. 201510466544.1, as filed on Jul. 30, 2015 and titled with “CHINESE MEDICINE EXTRACT AND PREPARATION METHOD AND APPLICATION THEREOF”, and the disclosure of which is incorporated herein by reference.The present invention relates to the field of traditional Chinese medicine, and in particular to a Chinese medicine extract, preparation method and use ...

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22-03-2018 дата публикации

PETASITES EXTRACT AND COMPOSITION AND METHOD FOR TREATING VIRAL INFECTIONS

Номер: US20180078594A1
Принадлежит:

The present invention relates to a extract or pharmaceutical composition thereof for use in a method for treating viral infections. 115.-. (canceled)16PetasitesPetasitesPetasitesPetasites. A method for the treatment of a viral infection in a mammal , comprising the step of administering to a mammal in need thereof , an effective amount of a extract or composition comprising a extract , wherein the effective amount of the extract or composition comprising a extract is effective in treating the viral infection.17. The method of claim 16 , wherein the viral infection is a viral respiratory tract infection.18. The method of claim 16 , wherein the viral infection is a viral skin infection.19. The method of claim 16 , wherein the viral infection is a viral rhinitis.20. The method of claim 16 , wherein the viral infection is a viral sinusitis.21PetasitesPetasites. The method of claim 16 , wherein the extract or extract composition is substantially free of pyrrolizidine-alkaloids.22PetasitesPetasitesPetasites. The method of claim 16 , wherein the extract or extract composition comprises a non-polar extract.23Petasites. The method of claim 16 , wherein the extract is produced by extraction with liquid carbon dioxide.24Petasites. The method of claim 23 , wherein the extract is produced by extraction with liquid carbon dioxide at subcritical temperature conditions.25PetasitesPetasites hybridus, Petasites albus, Petasites amplus, Petasites fragrans, Petasites formosanus, Petasites frigidus, Petasites georgicus, Petasites japonicus, Petasites laevigatus, Petasites kablikianus, Petasites niveus, Petasites paradoxus, Petasites pyrenaicus, Petasites tricholobus, Petasites radiates, Petasites sagittatusPetasites spurius.. The method of claim 16 , wherein the extract is obtained from plants and/or parts of plants selected from the group consisting of claim 16 , and26. The method of claim 16 , wherein the viral respiratory disease is selected from the group consisting of exacerbation ...

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23-03-2017 дата публикации

COMPOSITIONS COMPRISING CANNABINOIDS FOR TREATMENT OF NAUSEA, VOMITING, EMESIS, MOTION SICKNESS OR LIKE CONDITIONS

Номер: US20170079933A1
Принадлежит: GW Pharma Limited

Cannabinoids, in particular CBD and CBDA and their acid derivatives are provided for use as an active pharmaceutical substance in the treatment of nausea, vomiting, emesis, motion sickness. In particular extracts of cannabis plants are presented which are rich in these substances and suitable for pharmaceutical use. 130.-. (canceled)31. A botanical drug substance (BDS) in the form of a subcritical COextract obtained from a high cannabidiol (CBD) containing cannabis plant , wherein said BDS comprises cannabinoid constituents and other chemical entities , wherein the cannabinoid constituents comprise at least 90% CBD and the other chemical entities include terpene or carotene rich volatile oils , said BDS having been purified by winterisation in ethanol and cold filtration to remove waxes and other non-specific lipid-soluble material , and any water and ethanol have been removed by evaporation.32. A crystalline cannabidiol (CBD) obtained by re-dissolving a BDS as claimed in in a suitable solvent claim 31 , filtering to remove insoluble material and then removing the solvent claim 31 , such that the crystalline CBD has a chromatographic purity of greater than 99% by area normalization and contains less than 0.1% each of tetrahydrocannabinol (THC) and cannabinol (CBN).33. The crystalline cannabidiol (CBD) as claimed in claim 32 , wherein the suitable solvent is pentane.34. A process of preparing a botanical drug substance (BDS) in the form of a subcritical COextract obtained from a high cannabidiol (CBD) containing cannabis plant comprising the following steps:i) Decarboxylate dry high CBD plant material by heating for a sufficient time and temperature to decarboxylate CBDA to CBD;ii) Extract with liquid carbon dioxide under subcritical conditions of 50 to 70 bar and 5 to 15° C. for up to 10 hours;iii) Removal of carbon dioxide by depressurization to recover crude extract;iv) Winterization in ethanol and cold filtration to remove waxes and other non-specific lipid- ...

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23-03-2017 дата публикации

PHARMACEUTICAL COMPOSITION FOR CONTROLLING BLOOD LIPIDS AND BODY WEIGHT, AND USE THEREOF

Номер: US20170080043A1
Автор: Zhou James
Принадлежит:

The invention provides a traditional Chinese medicine composition for the control of blood lipids and/or weight of body, which includes Poria and Paeoniae Radix Alba, etc. the traditional Chinese medicine composition can be applied in reducing the total cholesterol level, triacylglycerol level, and low density lipoprotein cholesterol level in the body; increasing body high density lipoprotein cholesterol level, reducing uric acid level, and/or reducing symptoms of fatty liver. The invention also provides preparation methods and applications of this traditional Chinese medicine composition. 1. The traditional Chinese medicine composition for control blood fat and/or body weight , including Poria , Paeoniae Radix Rubra and at least one crude drugs selected from the group consisting of:Group A: Moutan Cortex and Cinnamomi Ramulus;Group B: Moutan Cortex, Cinnamomi Ramulus, Persicae Semen and Glycyrrhizae Radix et Rhizoma; and,Group C: Salviae miltiorrhizae Radix et Rhizoma, Curcumae longae Rhizoma and Coptidis Rhizoma.2. The traditional Chinese medicine composition specified in claim 1 , wherein a weight proportion of main crude drug is:Poria for 3 parts approximately, Paeoniae Radix Rubra for 3 parts approximately, Moutan Cortex for 3 parts approximately, Cinnamomi Ramulus for 3 parts approximately, Persicae Semen for 3 parts approximately, and Glycyrrhizae Radix et Rhizoma for 2 parts approximately, Salviae miltiorrhizae Radix et Rhizoma for parts approximately, Curcumae longae Rhizoma for 3 parts approximately, Coptidis Rhizoma for 1.2 parts approximately.3. A method for preparing the traditional Chinese medicine composition specified in claim 1 , wherein a preparation process includes adding water and/or alcohol decoction; it is preferable adding water and decoction in an open container.4. The method of claim 3 , further comprising:(1) crush and mix the crude drug, and obtain mixed powder of the crude drug;(2) add water into and soak the mixed powder of crude drug ...

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31-03-2022 дата публикации

CANNABINOIDS INFUSED CONSUMABLES

Номер: US20220096581A1
Принадлежит:

The present disclosure is directed to cannabinoids infused coffee beans, nuts, and seeds consumables and methods of producing the cannabinoid infused consumables. The consumables are infused in an overall two-step process, in which cannabinoids from a species are first infused into coconut oil, which in turn is used to infuse a consumable of choice with cannabinoids to generate the cannabinoids infused consumables. 1. A method of infusing an orally ingestible oil with at least one cannabinoid , the method comprising:{'i': 'cannabis', '#text': '(A) providing plant material;'}{'i': 'cannabis', '#text': '(B) freezing the plant material for about 24 hours;'}(C) providing an orally ingestible oil at a temperature of 150° F.-200° F.;{'i': ['cannabis', 'cannabis'], '#text': '(D) adding at least a portion of the of (B) to the oil of (C) to form a first and oil mixture;'}{'i': 'cannabis', '#text': '(E) keeping the and oil mixture of (D) at a temperature of 150° F.-200° F. for 4-8 hours;'}{'i': 'cannabis', '#text': '(F) freezing the and oil mixture of (E) and keeping it frozen for 8-12 hours;'}{'i': 'cannabis', '#text': '(G) heating the and oil mixture of (F) to a temperature of 150° F.-200° F. for 2-4 hours;'}{'i': ['cannabis', 'cannabis'], '#text': '(H) straining the and oil mixture of (G) to separate the oil from the to yield a cannabinoids infused orally ingestible oil; and'}(I) heating the cannabinoids infused oil of (H) to a temperature of 250° F. for 2 hours.2cannabisCannabis sativa, Cannabis indicaCannabis ruderalis.. The method of wherein the provided in (A) includes one or more selected from the group consisting of claim 1 , and3. The method of wherein the oil provided in (C) is selected from the group consisting of coconut oil claim 1 , MCT oil claim 1 , or a combination thereof.4. The method of wherein the oil provided in (C) is a combination of coconut oil and MCT oil at a ratio of 75% coconut oil to 25% MCT oil.5. The method of wherein the temperature in (C) and ...

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31-03-2022 дата публикации

CANNABINOIDS INFUSED CONSUMABLES AND NON-CONSUMABLES

Номер: US20220096582A1
Принадлежит:

The present disclosure is directed to cannabinoids infused consumables and non-consumables and methods of producing the cannabinoid infused consumables and non-consumables. The consumables are infused in an overall two-step process, in which cannabinoids from a species are first infused into coconut oil, which in turn is used to infuse a food or beverage of choice with cannabinoids to generate the cannabinoids infused consumables. The non-consumables are produced by adding a cannabinoids infused oil to the non-consumables. 1. A method of infusing an orally ingestible oil with at least one cannabinoid , the method comprising:(A) providing cannabis plant material;(B) freezing the cannabis plant material for about 24 hours;(C) providing an orally ingestible oil selected from the group consisting of coconut oil, MCT oil, vegetable oil, sunflower oil, olive oil, grape seed oil, and combinations thereof at a temperature of 150° F.-200° F.;(D) adding at least a portion of the cannabis of (B) to the oil of (C) to form a first cannabis and oil mixture;(E) keeping the cannabis and oil mixture of (D) at a temperature of 150° F.-200° F. for 4-8 hours;(F) freezing the cannabis and oil mixture of (E) and keeping it frozen for 8-12 hours;(G) heating the cannabis and oil mixture of (F) to a temperature of 150° F.-200° F. for 2-4 hours;(H) straining the cannabis and oil mixture of (G) to separate the oil from the cannabis to yield a cannabinoids infused orally ingestible oil; and(I) heating the cannabinoids infused oil of (H) to a temperature of 250° F. for 2 hours.2Cannabis Sativa, Cannabis IndicaCannabis Ruderalis.. The method of wherein the cannabis provided in (A) includes one or more selected from the group consisting of claim 1 , and3. The method of wherein the temperature in (C) and (E) is about 175° F.4. The method of claim 1 , wherein the plant material and oil are provided at a ratio of 1 pound plant material to 2 gallons of oil.5. The method of claim 1 , wherein the ...

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31-03-2022 дата публикации

CANNABINOIDS INFUSED COFFEE BEANS AND RAW NUTS

Номер: US20220096583A1
Принадлежит:

The present disclosure is directed to whole spectrum cannabinoids infused coffee beans or raw nuts and methods of producing the cannabinoids infused coffee beans or raw nuts. The coffee beans or raw nuts are infused in an overall two-step process, in which cannabinoids from a species are first infused into coconut oil, which in turn is used to infuse coffee beans or raw nuts with cannabinoids to generate the cannabinoids infused coffee beans or raw nuts. 1cannabis. A method of infusing an orally ingestible consumable with whole spectrum cannabinoids , the method comprising:{'i': 'cannabis', '(A) providing plant material;'}{'i': 'cannabis', '(B) freezing the plant material;'}(C) providing an orally ingestible oil at a temperature of 150° F.-200° F.;{'i': cannabis', 'cannabis, '(D) adding at least a portion of the frozen plant material of (B) to the oil of (C) to form a first plant material and oil mixture;'}{'i': 'cannabis', '(E) heating the plant material and oil mixture of (D) to a temperature of 150° F.-200° F. for 5-7 hours;'}{'i': 'cannabis', '(F) freezing the plant material and oil mixture of (E) into a solid, frozen biomass;'}{'i': 'cannabis', '(G) heating the solid, frozen biomass of plant material and oil mixture of (F) at a temperature of 150° F.-200° F. for 2-4 hours;'}{'i': cannabis', 'cannabis, '(H) straining the plant material and oil mixture of (G) to separate the oil from the plant material to yield a whole spectrum cannabinoids infused orally ingestible oil;'}(I) heating the cannabinoids infused oil of (H) to a temperature of 250° F. to 300° F. for 3-6 hours;(J) adding an orally ingestible consumable to the cannabinoids infused oil of (I) to form a consumable and cannabinoids infused oil mixture;(K) heating the mixture of (J) to a temperature of 175° F.-189° F. for 5-6 hours;(L) freezing the mixture of (K) to form a solid, frozen biomass mixture of consumable and cannabinoids infused oil;(M) heating the solid, frozen biomass mixture of consumable and ...

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31-03-2022 дата публикации

CANNABINOIDS INFUSED CONSUMABLES

Номер: US20220096584A1
Принадлежит:

The present disclosure is directed to cannabinoids infused consumables, including cacao beans, dehydrated fruit, and raw popcorn kernels, along with methods of producing the cannabinoid infused cacao beans, dehydrated fruit, and raw popcorn kernels. The consumables are infused in an overall two-step process, in which cannabinoids from a species are first infused into coconut oil, which in turn is used to infuse cacao beans, dehydrated fruit and raw popcorn kernels with cannabinoids to generate the cannabinoids infused cacao beans, dehydrated fruit and raw popcorn kernels. 1cannabis. A method of infusing an orally ingestible consumable with whole spectrum cannabinoids , the method comprising:{'i': 'cannabis', '#text': '(A) providing plant material;'}{'i': 'cannabis', '#text': '(B) freezing the plant material;'}(C) providing an orally ingestible oil at a temperature of 150° F.-200° F.;{'i': ['cannabis', 'cannabis'], '#text': '(D) adding at least a portion of the frozen plant material of (B) to the oil of (C) to form a first plant material and oil mixture;'}{'i': 'cannabis', '#text': '(E) heating the plant material and oil mixture of (D) to a temperature of 150° F.-200° F. for 5-7 hours;'}{'i': 'cannabis', '#text': '(F) freezing the plant material and oil mixture of (E) into a solid, frozen biomass;'}{'i': 'cannabis', '#text': '(G) heating the solid, frozen biomass of plant material and oil mixture of (F) at a temperature of 150° F.-200° F. for 2-4 hours;'}{'i': ['cannabis', 'cannabis'], '#text': '(H) straining the plant material and oil mixture of (G) to separate the oil from the plant material to yield a whole spectrum cannabinoids infused orally ingestible oil;'}(I) heating the cannabinoids infused oil of (H) to a temperature of 250° F. to 300° F. for 3-6 hours;(J) adding an orally ingestible consumable to the cannabinoids infused oil of (I) to form a consumable and cannabinoids infused oil mixture;(K) heating the mixture of (J) to a temperature of 175° F.-195° F. ...

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21-03-2019 дата публикации

METHOD FOR CONDUCING CONCENTRATED CANNABIS OIL TO BE STABLE, EMULSIFIABLE AND FLAVORLESS FOR USE IN HOT BEVERAGES AND RESULTING POWDERIZED CANNABIS OIL

Номер: US20190082721A1
Принадлежит:

A method for producing powderized cannabis oil, and the resulting powderized cannabis oil, in which concentrated cannabis oil is mixed with and absorbed by a modified starch powder, preferably maltodextrin, in a ratio of at least three grams of starch powder for every one-eighth of a gram of cannabis oil is disclosed. Further disclosed are beverages, baked goods and single-serve beverage brewing cartridges utilizing or incorporating the powderized cannabis oil to create human-consumable products that contain an emulsified, tasteless, and odorless dose of cannabis oil. 1. A method for making powderized cannabis oil with a modified terpene profile , comprising the steps of:selecting a cannabis oil;measuring a desired quantity of the cannabis oil;selecting a first human consumable powder;measuring a desired quantity of the first human consumable powder to achieve a ratio of the first human consumable powder to the cannabis oil, by weight;wherein the ratio of the first human consumable powder to the cannabis oil, by weight, is at least three grams of first human consumable powder to every one-half of a gram of cannabis oil;mixing the cannabis oil and the first human consumable powder until the cannabis oil is evenly absorbed by the first human consumable powder to create a powderized cannabis oil;selecting a terpene oil;measuring a desired quantity of the terpene oil;selecting a second human consumable powder;mixing the terpene oil and the second human consumable powder until the terpene oil is evenly absorbed by the second human consumable powder to create a terpene oil powder; andmixing the powderized cannabis oil and the terpene oil powder until the terpene oil powder is evenly distributed throughout the powderized cannabis oil.2. The method of wherein the first human consumable powder is maltodextrin.3. The method of wherein the ratio of the first human consumable powder to the cannabis oil claim 1 , by weight claim 1 , is at least three grams of the first human ...

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21-03-2019 дата публикации

Vitamin D Composition

Номер: US20190083514A1
Принадлежит:

The invention is directed to compositions of vitamin D having enhanced bioavailability and enhanced stability. Methods of making and using the compositions of the invention are contemplated and disclosed. 115-. (canceled)16. A composition of vitamin D having enhanced stability and enhanced bioavailability , the composition comprising vitamin D in contact with at least one comestible oil , wherein said contact increases the bioavailability and stability of said vitamin D compared to control vitamin D that has not been contacted with said comestible oil.17. The composition of claim 16 , wherein said vitamin D is selected from the group consisting of vitamin D2 claim 16 , vitamin D3 claim 16 , and a combination thereof.18. The composition of claim 16 , wherein said comestible oil is selected from the group consisting of tomato seed oil claim 16 , corn oil claim 16 , olive oil claim 16 , canola oil claim 16 , palm oil claim 16 , safflower oil claim 16 , sunflower oil claim 16 , sesame oil claim 16 , peanut oil claim 16 , coconut oil claim 16 , rapeseed oil claim 16 , grapeseed oil claim 16 , soybean oil claim 16 , cotton seed oil claim 16 , and combinations thereof.19. The composition of claim 16 , wherein said vitamin D retains at least 90 percent of its activity 30 days after it is contacted with said comestible oil.20. The composition of claim 16 , wherein said vitamin D retains at least 86 percent of its activity 60 days after it is contacted with said comestible oil.21. The composition of claim 16 , wherein said vitamin D retains at least 72 percent of its activity 90 days after it is contacted with said comestible oil.22. The composition of claim 16 , wherein said contact increases the bioavailability of said vitamin D by about 2 fold.23. The composition of claim 16 , wherein at least one of said vitamin D and said comestible oil are purified.24. The composition of claim 16 , wherein said vitamin D is tomato leaf vitamin D.25. The composition of claim 16 , wherein ...

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05-05-2022 дата публикации

Herbal Tea Products and Methods

Номер: US20220132882A1
Автор: Guzman Rene O.
Принадлежит:

An herbal tea product is provided to provide relief from lung and breathing conditions such as asthma. The herbal tea product may include oregano, peppermint, OSHA root, lungwort, eucalyptus, plantain leaf, chaparral, elecampane, lobelia, sage, licorice root, and thyme. The herbal ingredients may be included in equal amounts, such as 5 ounces. The OSHA root, elecampane, and/or licorice root may be crushed. Methods of making and using the herbal tea product are also disclosed. The herbal tea product may be placed into tea bags, and prepared for human consumption by placing the tea bag with herbal tea product in hot water that has been brought to a boil. The herbal tea product may be consumed in appropriate amounts, such as 16 ounces, twice a day for two weeks, and then once a day thereafter.

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05-05-2022 дата публикации

Compositions of Azadirachta Indica and Methods of Treating Cancer

Номер: US20220133680A1
Автор: Wargovich Michael
Принадлежит:

The disclosure relates to compositions and methods of treating cancer in a subject. The method comprises administering to a patient in need of treatment an effective amount of supercritical COneem extract.

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12-05-2022 дата публикации

FUKE QIANJIN CAPSULE AND QUALITY CONTROL METHOD THEREFOR

Номер: US20220143125A1
Принадлежит: QIANJIN PHARMACEUTICAL CO., LTD.

The present invention discloses Fuke Qianjin Capsules and a quality control method therefor. The capsules are made of Radix Et Caulis Flemingiae, Caulis Mahoniae, Herba Andrographis, Zanthoxylum dissitum Hemsl., Caulis Spatholobi, Radix Angelicae Sinensis, Radix Codonopsis, and Radix Rosa Laevigata as raw materials. Each of the Fuke Qianjin Capsules contains not less than 2.0 mg of Z-ligustilide, and a total amount of andrographolide and dehydroandrographolide is not less than 1.9 mg. A new standard for controlling quality of the Fuke Qianjin Capsules has been established through an analysis of chemical ingredients in the Fuke Qianjin Capsules. This standard adds a variety of core ingredient content to the existing pharmacopoeia standards. According to the Fuke Qianjin Capsules made in this range, the consistency of effects between different batches is more stable. Moreover, the more the types of core ingredients are limited, the more stable the consistency of the drug effect. 1. A quality control method for Fuke Qianjin Capsules , wherein the quality control method comprises the following steps:using Radix Et Caulis Flemingiae, Radix Rosa Laevigata, Herba Andrographis, Radix Angelicae Sinensis, Caulis Mahoniae, Zanthoxylum dissitum Hemsl., Caulis Spatholobi and Radix Codonopsis as raw materials;S1, first extracting the Radix Angelicae Sinensis by ethanol percolating to prepare a cream;S2, extracting the Herba Andrographis by ethanol refluxing to prepare a cream;S3, boiling and extracting the Caulis Mahoniae and the Zanthoxylum dissitum Hemsl. with water twice, after filtering, combining two filtrates to prepare a cream;S4, boiling and extracting the Radix Et Caulis Flemingiae, the Radix Rosa Laevigata, the Caulis Spatholobi, and the Radix Codonopsis with water once and then filtering, boiling with water a filtered residue with a Radix Angelicae Sinensis residue produced in the step S1, an Herba Andrographis residue produced in the step S2 and a Caulis Mahoniae and ...

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28-03-2019 дата публикации

Method for conducing concentrated cannabis oil to be stable, emulsifiable and flavorless for use in hot beverages and resulting powderized cannabis oil

Номер: US20190090512A1
Принадлежит: Pivot Naturals LLC

A method for producing powderized cannabis oil, and the resulting powderized cannabis oil, in which concentrated cannabis oil is mixed with and absorbed by a modified starch powder, preferably maltodextrin, in a ratio of at least three grams of starch powder for every one-eighth of a gram of cannabis oil is disclosed. Further disclosed are beverages, baked goods and single-serve beverage brewing cartridges utilizing or incorporating the powderized cannabis oil to create human-consumable products that contain an emulsified, tasteless, and odorless dose of cannabis oil.

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28-03-2019 дата публикации

METHOD FOR CONDUCING CONCENTRATED CANNABIS OIL TO BE STABLE, EMULSIFIABLE AND FLAVORLESS FOR USE IN HOT BEVERAGES AND RESULTING POWDERIZED CANNABIS OIL

Номер: US20190090515A1
Принадлежит:

A method for producing powderized cannabis oil, and the resulting powderized cannabis oil, in which concentrated cannabis oil is mixed with and absorbed by a modified starch powder, preferably maltodextrin, in a ratio of at least three grams of starch powder for every one-eighth of a gram of cannabis oil is disclosed. Further disclosed are beverages, baked goods and single-serve beverage brewing cartridges utilizing or incorporating the powderized cannabis oil to create human-consumable products that contain an emulsified, tasteless, and odorless dose of cannabis oil. 1. A tablet or capsule consisting essentially of cannabis oil and carboxymethyl cellulose.2. The tablet or capsule of claim 1 , wherein the ratio of the carboxymethyl cellulose to the cannabis oil claim 1 , by weight claim 1 , is at least three grams of carboxymethyl cellulose to every one-half of a gram of cannabis oil.3. The tablet or capsule of claim 1 , wherein the ratio of the carboxymethyl cellulose to the cannabis oil claim 1 , by weight claim 1 , is at least three grams of carboxymethyl cellulose to every one-eighth of a gram of cannabis oil.4. The tablet or capsule of claim 1 , wherein the ratio of the carboxymethyl cellulose to the cannabis oil claim 1 , by weight claim 1 , is at least five grams of carboxymethyl cellulose to every one-eighth of a gram of cannabis oil.5. The tablet or capsule of claim 1 , wherein the ratio of the carboxymethyl cellulose to the cannabis oil claim 1 , by weight claim 1 , is no more than one-eighth of a gram of cannabis oil to every three grams of carboxymethyl cellulose.6. The tablet or capsule of claim 1 , wherein the ratio of the carboxymethyl cellulose to the cannabis oil claim 1 , by weight claim 1 , is between three grams and six grams of carboxymethyl cellulose to every one-eighth of a gram of cannabis oil.7. The tablet or capsule of claim 1 , wherein the cannabis oil is evenly absorbed by the carboxymethyl cellulose.8. The tablet or capsule of wherein ...

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05-04-2018 дата публикации

COMPOSITION FOR AMELIORATION OF PERI- AND POST- MENOPAUSAL SYMPTOMS AND A PROCESS FOR PRODUCING THE SAME

Номер: US20180092956A1
Принадлежит:

The present invention provides a nutraceutical composition, a process for the preparation of the nutraceutical composition useful for amelioration of pen- and post-menopausal symptoms in women. The nutraceutical composition is stable, directly compressible, water soluble, free flowing form having particle size not more than 2.0 μm comprising extract of -, at least one bioavailable form of magnesium and vitamin E. The present invention also provides a method of treating ameliorating, treating and/or preventing pen- and post-menopausal discomforts in a subject suffering from pen- or post-menopausal symptoms comprising administering to the subject a therapeutically effective amount of the nutraceutical composition. 1Trigonella foenumgraecum. A nutraceutical composition comprising extract of -; at least one bioavailable form of magnesium and vitamin E , characterized in that the composition is stable , directly compressible , water soluble , free flowing form having particle size not more than 2.0 μm.2Trigonella foenumgraecum. The composition of claim 1 , wherein the extract of -comprises at least one of a steroidal saponins selected from the group comprising protodioscin claim 1 , diosgenin and yamogenin; an alkaloid claim 1 , trigonellin; and claim 1 , a non-proteinogenic amino acid claim 1 , 4-hydroxyisoleucine.3Trigonella foenumgraecum. The composition of claim 1 , wherein the phytoestrogens present in 1 g of the composition is at an equivalent dose of 15 to 30 g of -seeds in natural state.4. The composition of claim 1 , wherein the vitamin E comprises any form of biologically active tocopherol claim 1 , especially alpha-D tocopherol or a mixture of tocopherols and tocotrienols from any natural source comprising alpha claim 1 , beta- claim 1 , gamma- claim 1 , or delta-tocopherols or tocotrienols claim 1 , or a mixture thereof in free form or in the form of salts.5. The composition of claim 1 , wherein the at least one bioavailable form of magnesium is selected from ...

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06-04-2017 дата публикации

Compositions Containing Extracts of Curcuma SPP and Zingiber officinale Which Are Useful to Reduce Peripheral Inflammation and Pain

Номер: US20170095522A1
Принадлежит: Indena SpA

Disclosed are compositions containing an extract of Curcuma spp, optionally as curcumin in the form of a complex with phospholipids, and a lipophilic extract of Zingiber officinale , for use in the treatment of osteoarthritis.

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08-04-2021 дата публикации

METHOD FOR EXTRACTING BIOACTIVE INGREDIENT AND BIOACTIVE INGREDIENT OBTAINED THEREBY

Номер: US20210100861A1
Автор: JIN Xiangfan
Принадлежит:

A method of extracting a bioactive ingredient, including the following steps: step 1) heating a pre-treated fresh raw material in a vacuum state; step 2) cooling an upper part of the raw material; step 3) collecting a liquid formed in step 2) and containing a bioactive substance; step 4) dispensing and storing the collected liquid containing the bioactive substance. 1cannabiscannabis. A method of extracting a bioactive ingredient , comprising the following steps: step 1) heating a fresh raw material after being subjected to a pretreatment in a vacuum state; step 2) cooling an upper part of the fresh raw material; step 3) collecting a liquid formed in the step 2) , wherein the liquid contains a bioactive substance; step 4) dispensing and storing the liquid containing the bioactive substance.2cannabiscannabiscannabis. The method of extracting the bioactive ingredient according to claim 1 , wherein the pretreatment of the fresh raw material in the step 1) comprises washing the fresh raw material with clean water and then keeping the fresh raw material for ultraviolet disinfection.3cannabiscannabis. The method of extracting the bioactive ingredient according to claim 2 , wherein in the step 1) claim 2 , the fresh raw material is placed in a vacuum negative pressure device for heating and depressurization claim 2 , and a material bin of the vacuum negative pressure device is cleaned and disinfected before the fresh raw material is placed.4. The method of extracting the bioactive ingredient according to claim 3 , wherein the vacuum state in the step 1) is 650 torr to 750 torr.5. The method of extracting a bioactive ingredient according to claim 4 , wherein a pressure drop to the vacuum state in the step 1) is completed within 3 hours.6cannabiscannabis. The method of extracting the bioactive ingredient according to claim 5 , wherein in the step 2) claim 5 , after the fresh raw material is heated for 3 hours claim 5 , a cooling device is activated to cool the upper part of ...

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02-06-2022 дата публикации

A Product and Process For A Room-Temperature Stable, Food-Grade, All-Natural, Vegan, And Phyto-Cannabinoid/Terpene/Flavonoid Colloidal Dispersion

Номер: US20220168371A1
Автор: Young Daniel L.
Принадлежит:

A method for producing a room-temperature stable, food-grade, all-natural, vegan, water-soluble, and phyto-cannabinoid/terpene/flavonoid colloidal dispersion by heating carrier oils and one or more than one plant extract. Mixing and heating the resultant together in a first container and adding flavor components. Mixing and heating water and one or more than one polyol in a second container. Mixing one or more than one emulsifier and one or more than one antioxidant in the second container. Mixing the contents of the first container and the second container in the first container after being removed from heat sources. Processing the resultant mixture through a high energy processor. Filtering the resultant mixture producing a room-temperature stable, food-grade, all-natural, vegan, water-soluble, and phyto-cannabinoid/terpene/flavonoid colloidal dispersion. Optionally adding an aqueous-based and lipid-based mixture to the resultant mixture that is bottled and stored in a light-protected environment and is ready for consumption. 1. A method for producing a room-temperature stable , food-grade , all-natural , vegan , water-soluble , and phyto-cannabinoid/terpene/flavonoid colloidal dispersion , the method comprising the steps of:a) heating carrier oils and one or more than one plant extract;b) mixing the heated carrier oils and the one or more than one plant extract together in a first container; 'wherein the flavoring components are natural plant extracts that are fat-soluble;', 'c) adding flavoring components to enhance the flavor profile of the emulsion during heating,'}d) mixing and heating water and one or more than one polyol in a second container;e) mixing and heating one or more than one emulsifier and one or more than one antioxidant in the second container;f) mixing the contents of the first container and the second container in the first container after being removed from heat sources to create and emulsion of a room-temperature stable, food-grade, all- ...

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02-06-2022 дата публикации

CONTROLLED CANNABIS DECARBOXYLATION FOR AN INFUSED SOLUBLE FAT PRODUCT

Номер: US20220168373A1
Автор: Guillory Rachel
Принадлежит:

A process for controlling a decarboxylation of acidic cannabinoids for an infused soluble fat product, such as a butter product, is disclosed. In one embodiment for producing a butter product, raw cannabis base material is dried, pulverized, heated, and cooled to produce a decarbed cannabis material. The decarbed cannabis material is mixed with unsalted butter in an about 22:1 to and about 26:1 ratio, by weight, at ambient temperature and pressure, to produce a heterogenous butter material. The heterogenous butter material is canned and subjected to in-container thermal processing, including agitation during the thermal processing. The resulting heterogenous butter material is separated before cooling produces the butter product. 1. A process for controlling a decarboxylation of acidic cannabinoids for a butter product , the process comprising:drying raw cannabis base material at ambient temperature and pressure to produce a dried raw cannabis material, the dried raw cannabis material having kief formed thereon;pulverizing the dried raw cannabis material into small pieces to produce a pulverized cannabis material;heating the pulverized cannabis material at a temperature of about 220° F. (104° C.) to about 225° F. (107° C.) degrees for about 40 minutes to about 55 minutes to produce a decarbed cannabis material;cooling the decarbed cannabis material to room temperature;mixing the decarbed cannabis material with unsalted butter in an about 22:1 to an about 26:1 ratio, by weight, at ambient temperature and pressure, to produce a heterogenous butter material;canning the heterogenous butter material;thermal processing of the canned heterogeneous butter material in-container by water bath canning at a sub-boiling temperature for about 3 hours to about 5 hours to produce a processed heterogenous butter material, the sub-boiling temperature being between about 204° F. (96° C.) to about 210° F. (99° C.)agitating, during the thermal processing, the processed heterogeneous ...

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19-04-2018 дата публикации

WATER EXTRACT FOR PROMOTION ON HYPERLIPIDEMIA, ATHEROGENESIS AND OBESITY

Номер: US20180104291A1
Принадлежит:

The invention provides a water extract of Yan-Sheng-Yin (YSY), a Chinese natural dietary supplement for health promotion, comprised entirely of natural foods and a preparation comprising the same. The invention also provides a method for treatment and/or prevention of hyperlipidemia, atherogenesis and obesity. 1Auricularia auricularLentinus edodesCrataegus pinnatifidaHibiscus sabdariffaApium graveolensPrunus mume. A water extract of a composition comprising wood ear () , shiitake () , hawthorn fruit () , roselle () , celery () and fruit of Chinese plum () , wherein the water extract is obtained by mixing wood ear , shiitake , hawthorn fruit , roselle , celery and fruit of Chinese plum to form a composition , soaking the composition in water for at least 16 hours at a temperature of about 50° C. to about 80° C. and cooking the resulting composition to boil to obtain the water extract of the composition;wherein the composition comprises compounds having retention time at about 3.2 to about 4.5 minutes and about 5.4 to about 6.2 minutes, respectively, as measured by HPLC;wherein the composition comprises compounds having retention times at about 4.61 minutes to 4.95 minutes, about 6.1 minutes to about 6.5 minutes, about 6.8 minutes to about 7.0 minutes, about 3.45 minutes to about 3.62 minutes and about 2.96 minutes to 3.16 minutes, respectively as measured by Extracted ion chromatogram (XIC) of multiple reaction monitoring (MRM), wherein the XIC of −MRM is detected at 153.000/109.000 Da of HPLC-MS/MS and protocatechuic acid is used as standard; orwherein the composition comprises compounds having retention times at about 4.35 minutes to about 4.65 minutes, about 3.41 minutes to about 3.62 minutes, about 4.0 minutes to about 4.15 minutes, about 3.8 minutes to about 4.0 minutes and about 5.18 minutes to about 5.4 minutes, respectively as measured by Extracted ion chromatogram (XIC) of multiple reaction monitoring (MRM), wherein the XIC of −MRM is detected at 153.000/109 ...

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20-04-2017 дата публикации

Antiobesity Agent Containing Walnut Extract

Номер: US20170106034A1
Принадлежит:

To provide an antiobesity agent. An antiobesity agent containing an extract of walnut branches, shells, or leaves as an active ingredient. 18-. (canceled)9. A method for treating obesity comprising a step of administering an antiobesity agent which comprises an extract of walnut branches.10. The method according to claim 9 , wherein the extract of walnut branches is an alcohol extract of walnut branches.11. The method according to claim 9 , wherein the treating obesity is preventing an increase in neutral fat amount claim 9 , cholesterol amount claim 9 , fat amount claim 9 , or body weight.12. The method according to claim 9 , wherein the treating obesity is inhibiting a binding between synoviolin and PGC-1β.13. The method according to claim 9 , wherein the treating obesity is inhibiting ubiquitination of PGC-1β by synoviolin.14. A method of manufacturing an antiobesity agent claim 9 , the method comprising:a first heating reflux step in which 1 part by weight of walnut branches is admixed with 4 to 30 parts by weight of an alcohol with concentration of 20 to 60 wt % to obtain a first mixture; and the first mixture is subjected at least once to heating reflux to obtain a first reflux liquid;a first filtering step in which the first reflux liquid obtained from the first heating reflux step is filtered to obtain a first filtrate and a first residue;a second heating reflux step in which 1 part by weight of the residue obtained from the first filtering step is admixed with 2 to 20 parts by weight of an alcohol with concentration of 20 wt % to 60 wt % to obtain a second mixture; and the second mixture is subjected at least once to heating reflux to obtain a second reflux liquid;a second filtering step in which the second reflux liquid obtained from the second heating reflux step is filtered to obtain a second filtrate;a first concentrating step in which the first filtrate is admixed with the second filtrate and then concentrated to have sugar content of 5% to 40% to ...

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20-04-2017 дата публикации

CHARDONNAY GRAPE SEED EXTRACT

Номер: US20170106037A1
Принадлежит: SHAKLEE CORPORATION

A novel grape seed extract is enriched in procyanidins, has total polyphenols of less than 70%, and has a low degree of polymerization (dp). Other fractions of the extract have minimal polyphenols, fiber, and protein, but contain more than 90% sugars. In some specific examples, the individual extracts are obtained by sequential ultrafiltration of a water extract of the grape seeds. A first ultrafiltration provides a first permeate (Fraction A) enriched in sugars which is useful as a flavorant, and a first retentate. The first retentate is reconstituted and subjected to a second ultrafiltration at a higher molecular weight cutoff to produce a second permeate (Fraction B) that is enriched in low molecular weight polyphenols, and a second retentate (Fraction C) that is enriched in seed fiber. The Fractions are individually suitable for different nutraceutical products, or can be combined with each other in any combination and/or with other nutraceutical agents to enhance vascular and cognitive health. 1. A method of extracting grape seeds , comprising:extracting washed grape seeds with heated water at a water temperature below the boiling point of water;enzymatically treating and fine-filtering the extract to substantially remove insoluble plant material in the extract and produce a clarified extract;processing the enzymatically treated extract by ultrafiltration to obtain a first permeate and a first retentate, wherein larger molecular weight polymers are removed from the first permeate, and the first permeate comprises at least 80% sugars;reconstituting the first retentate as a reconstituted first retentate, then processing the first reconstituted retentate by ultrafiltration to obtain a second permeate that contains polyphenols having a mean degree of polymerization (mdp) of less than 3, and a second retentate enriched in fiber and polyphenols, wherein the polyphenols have a mdp of greater than 5.2. The method of claim 1 , further comprising concentrating and/or ...

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29-04-2021 дата публикации

Compositions Comprising Molecularly Separated Cannabinoids and Terpene Blends and Methods of Producing

Номер: US20210121404A1
Автор: Melissa PARKER

An oral cannabis composition comprising molecularly separated cannabinoids, MCT oil and a terpene blend. A method of producing the oral cannabis composition comprising the steps of a) producing cannabis extract by supercritical carbon dioxide extraction; b) after step a), winterizing the cannabis extract; c) after step b), distilling the winterized cannabis extract to produce molecularly separated cannabinoids; d) after step c), mixing the molecularly separated cannabinoids with MCT oil; and e) after step d), mixing the mixture of MCT oil and molecularly separated cannabinoids with a terpene blend. A second method comprises the steps of a) selecting a desired mixture of molecularly separate cannabinoids; b) after step a), mixing the molecularly separated cannabinoids with MCT oil; and c) after step b), mixing the mixture of MCT oil and molecularly separated cannabinoids with a terpene blend.

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02-04-2020 дата публикации

AQUEOUS EXTRACTION PROCESS OF PLANTS, METHOD THEREOF, AND PRODUCT BY PROCESS

Номер: US20200101126A1
Принадлежит:

The preparation of an aqueous extract resulting from an aqueous extraction process of and and the chemical composition comprising said extract or fraction thereof, and the use of said composition or fraction thereof for treating or preventing cancers and inflammation related diseases, hair loss, stimulating hair growth, increasing energy production, and boosting immunity. 1. An aqueous extraction system comprising:an extraction vessel configured to store a fibrous container and a volume of water;a heating element configured to heat said volume of water within said extraction vessel, thereby creating water vapor and heated water;{'i': Cinnamomum cassia, Arctium lappa, Vitex agnus castus, Lonicera japonica, Acanthopanax gracilistylis, Raphanus sativus, Astragalus membranaceus', 'Hordeum vulgare;, 'a dry mixture placed within said fibrous container, said dry mixture comprised of one or more elements selected from the group consisting of: and'}said heated water configured to draw volatiles and an extraction mixture from said dry mixture;a condenser connected to said extraction vessel, said condenser configured to remove water vapor and volatiles; andsaid extraction mixture configured to be used as a treatment.2. The system of claim 1 , further comprising:a purified water reservoir and a first pump, said first pump configured to draw said volume of water from said purified water reservoir into said extraction vessel; andat least one valve, at least one second pump, and at least one filter aligned in a series and configured to draw said extraction mixture from said extraction vessel into one or more storage containers.3. The system of claim 1 , further comprising:{'i': Cinnamomum cassia,', 'Arctium lappa,', 'Vitex agnus castus,', 'Lonicera japonica,', 'Acanthopanax gracilistylis,', 'Raphanus sativus,', 'Astragalus membranaceus', 'Hordeum vulgare, 'said dry mixture comprising 220 mg of 110 mg 220 mg 110 mg 110 mg 110 mg 110 mg and 220 mg for each liter of said volume of ...

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09-06-2022 дата публикации

DIETARY SUPPLEMENT COMPRISING LUTEIN FOR TELOMERE PROTECTION, AND METHOD FOR PRODUCTION THEREOF

Номер: US20220175693A1
Принадлежит: BIOGEN EXTRACTS PRIVATE LIMITED

This invention discloses a dietary supplement composition. More particularly, the invention deals with the method of production of dietary supplement composition comprising natural lutein and tocopherols, optionally along with acceptable additives to a subject, wherein the dietary supplement composition reduces, ameliorates, prevents, or reverses the oxidative DNA damage and slows telomere shortening. Invention further describes a method for promoting detoxification in cells of a subject, including administering to the subject an oral formulation comprising a plurality of agents that stimulate natural stem cell production within the body; repair the stem cells fibroblasts; pro-long the replicative lifespan; slow the telomere shortening; improve the telomerase activation in stem cells; improve the telomerase activation in body cells; promote the health-span in humans; and reduce the oxidative stress. The present invention can be used for the development of functional food, dietary plan and as a nutritional supplement. 1) A method of reducing , ameliorating , preventing , or reversing oxidative DNA damage in a subject , comprising orally administering an effective dose of a dietary supplement composition comprising natural lutein and tocopherols , optionally along with acceptable additives to a subject , wherein the dietary supplement composition reduces , ameliorates , prevents , or reverses the oxidative DNA damage and slows telomere shortening.2) The method of claim 1 , wherein the dietary supplement composition comprising natural lutein is produced by a method comprising:a. saponifying Marigold Oleoresin in the presence of an alcohol or organic solvent and an alkali for about 2 hours at a preferable temperature of about 80 to 85 degrees centigrade;b. adding an aqueous solution to the reaction mass, hereby obtaining a neutralized mass;c. filtering the neutralized mass, to obtain the Lutein crystals;d. further crystalizing the Lutein crystals in the presence of ...

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09-06-2022 дата публикации

DISSOLVABLE THC BEVERAGE TABLET PRODUCTION METHOD

Номер: US20220175719A1
Принадлежит:

The invention comprises a method, comprising the steps of: pressing into a dissolvable tablet at least one of: a carbonic acid, HCO; a bicarbonate, HCO; a salt of bicarbonate; a carbonate, CO; and a salt of carbonate; and distributing at least one milligram of a product in the dissolvable tablet, where the product is optionally and preferably at least one milligram of tetrahydrocannabinol. Optionally and preferably at least one of: a hydrogen phosphate; an ionic phosphate; monocalcium phosphate; a phosphate; and an acid is incorporated into the dissolvable tablet. 1. A method , comprising the steps of: [{'sub': 2', '3, 'a carbonic acid, HCO;'}, {'sub': '3', 'sup': '−', 'a bicarbonate, HCO;'}, 'a salt of bicarbonate;', {'sub': '3', 'sup': '2−', 'a carbonate, CO; and'}, 'a salt of carbonate; and, 'pressing a gassing agent into a dissolvable tablet, said gassing agent comprising at least one of{'i': 'Cannabis', 'distributing at least one milligram of a product in said dissolvable tablet.'}2. The method of claim 1 , said step of distributing comprising the step of:placing at least one milligram of tetrahydrocannabinol in said dissolvable tablet.3. The method of claim 2 , further comprising the steps of:forming a pre-made tablet of said gassing agent at a facility outside of a licensed THC manufacturing facility;shipping said pre-made tablet into the licensed THC manufacturing facility; andinfusing said pre-made tablet with said tetrahydrocannabinol to form said dissolvable tabletspraying a bonding agent onto said pre-made tablet;spraying the tetrahydrocannabinol onto said bonding agent an alcohol flavoring;', 'a gin flavoring; and', 'a tequila flavoring packaging said dissolvable tablet in a container; and, 'incorporating into said dissolvable tablet at least two of a location of harvest of a plant containing the tetrahydrocannabinol;', 'a date of harvest of the plant containing the tetrahydrocannabinol;', 'a THC strain of the tetrahydrocannabinol; and', 'a method of ...

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09-06-2022 дата публикации

GRAPE EXTRACT, METHOD FOR PRODUCING GRAPE EXTRACT LIQUID, METHOD FOR PRODUCING EXTRACTED AND PURIFIED PRODUCT OF GRAPE, AND METHOD FOR PRODUCING DRIED PRODUCT OF EXTRACTED AND PURIFIED PRODUCT OF GRAPE

Номер: US20220175867A1
Автор: NISHIZAWA Naomi
Принадлежит: ZEON CORPORATION

Disclosed is a method for producing a grape extract which comprises extracting a grape at an extraction temperature of 15° C. or higher and 50° C. or lower using an extractant containing a polar solvent and an acid component. Also disclosed is a grape extract which comprises malvidin-3,5-diglucoside and a saccharide, wherein a dry mass content of the malvidin-3,5-diglucoside is 3% by mass or more, and a dry mass content of the saccharide is 80% by mass or less. 1. A grape extract comprising malvidin-3 ,5-diglucoside and a saccharide ,wherein a malvidin-3,5-diglucoside content in dry mass of the grape extract is 3% by mass or more, anda saccharide content in dry mass of the grape extract is 80% by mass or less.2. A method for producing a grape extract liquid , comprising extracting a grape at an extraction temperature of 15° C. or higher and 50° C. or lower using an extractant containing a polar solvent and an acid component.3. The method according to claim 2 , wherein the polar solvent comprises at least one solvent selected from the group consisting of water claim 2 , methanol claim 2 , ethanol claim 2 , isopropanol claim 2 , butanol claim 2 , propylene glycol claim 2 , butylene glycol claim 2 , glycerin claim 2 , acetone claim 2 , ethyl acetate claim 2 , methyl ethyl ketone claim 2 , dimethylformamide claim 2 , dimethyl sulfoxide claim 2 , and tetrahydrofuran.4. The method according to claim 2 , wherein the extractant comprises at least one acid selected from the group consisting of formic acid claim 2 , citric acid claim 2 , lactic acid claim 2 , malic acid claim 2 , tartaric acid claim 2 , succinic acid claim 2 , hydrochloric acid claim 2 , and phosphoric acid.5Vitis Coignetiae, Vitis flexuosaVitis CoignetiaeVitis flexuosaVitis CoignetiaeVitis ViniferaVitis flexuosaVitis Vinifera.. The method according to claim 2 , wherein the grape comprises a pericarp of one or more types of grapes selected from the group consisting of claim 2 , a cross species between and ...

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26-04-2018 дата публикации

METHOD OF EXTRACTION OF BERRIES OR FRUITS USING AN ALKALINE MAGNESIUM COMPOUND FOR PHARMACEUTICAL, HERBAL, NUTRITIONAL OR COSMETIC INGREDIENTS

Номер: US20180111057A1
Автор: REIJONEN Mika Tapio
Принадлежит:

The invention is a method of extraction of berries or fruits of ( )) with a solvent ( )), typically water, and also an alkaline magnesium compound ( )) and heating a mixture ( )), the mixture is allowed to cool and is obtained berry and fruit materials in soluble form ( )) which is decanted or used wholly in the pharmaceutical, dietary supplement, herbal, or cosmetic product ingredients. 11111aacb. A method of extraction berries including substances ()) using of heat in the pharmaceutical , dietary supplement , herbal , or cosmetic product ingredients , is characterized in that in the extraction of the substances ( )) use the solvent ( )) , typically water , and also an alkaline magnesium compound ()).21b. The method according to the is characterized in that the magnesium containing alkaline compound ()) is magnesium oxide claim 1 , magnesium hydroxide claim 1 , magnesium carbonate claim 1 , dolomite claim 1 , brucite claim 1 , talc or magnesite claim 1 , or mixtures thereof.311bc. The method according to the is characterized in that the magnesium-containing compound ()) at the beginning is magnesium claim 1 , which reacts with the solvent ( )) claim 1 , typically water claim 1 , to form the alkaline magnesium compound.41c. The method according to the is characterized in solvent ( )) is water claim 1 , ethanol claim 1 , ethanol aqueous solution or an oil such as vegetable oil.51a. The method according to the is characterized in that the berry or fruit ( ) contained in is the whole and/or pressed claim 1 , dried or fresh in different milling sizes.61aVitisPrunus domesticaVacciniumVaccinium vitisidaeaVaccinium oxycoccosEmpetrum nigrumVaccinium uliginosumRubus chamaemorusHippophae rhamnoidesSorbusaroniaAroniaRibes nigrumRibes rubrumRibes rubrum rubrumRibes uvacrispaRubus idaeusRosa caninaFragariaLycium barbarumacaiacaiPrunus persicaCerasusPrunusActinidia deliciosCucumis sativusSolanum lycopersicumMalusAdansoniaCeratonia siliquaPhysalis peruvianaMorus albaMyrciaria ...

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18-04-2019 дата публикации

THE TOPICAL COMPOSITION WITH ACTIVE COMPOUNDS FROM CANNABIS SATIVA AND CALENDULA OFFICINALIS FOR REDUCTION OF SKIN LESIONS

Номер: US20190111093A1
Принадлежит:

Disclosed is a topical composition including essential combination of synergistically acting phyto-active materials, non-psychotropic phytocannabinoids from the plant of : Cannabidiol, Cannabidiolic acid, Cannabivarin Cannabigerol in combination with extract of flower and the formulation of the base to ensure the features of anti-inflammation, anti-oxidation, emollient, and bactericidal components. The topical composition is an emollient dedicated for reduction of skin lesions caused by atopic dermatitis, urticaria, radiotherapy and UV induced skin damage and acne. In addition the topical composition could reduce secretion of fats, facilitate deep skin hydration, reduce pores and exert soothing effect. 1Aloe barbadensisOlive europaeaOliveCalendula Officinalis. A topical composition comprising of about 8.76% Caprylic/capric triglyceride , 5.64% leaf juice , 0.94% Stearic acid , 0.52% Glycerol monostearate , 0.25% Trietanolamine , 0.4% Vitamin E , 74.89% Water (Distilled) , 3.33% () Fruit Oil , 3.33% Glycerol , 0.6% Acrylates/C10-30 alkyl acrylate crosspolymer , 0.07% Flower Extract , 0.8% Phenoxyethanol ,{'i': Cannabis sativa', 'Cannabis sativa', 'Cannabis sativa, 'wherein it comprises 0.75-1% decarboxylated extract (0.25% of CBD) and 0.75-1% non-carboxylated extract (0.25% CBDA), where extract comprises ˜80% of CBDA from the total cannabinoids, and THC is less than 0.1%.'}2Cannabis sativaCannabis sativa. A topical composition according to claim 1 , wherein extract is made from any non-psychotropic variety.3. A method for producing a topical composition for relieving skin discomfort comprising steps:{'i': 'Cannabis sativa', 'sub': '2', 'a) extraction of extract, in amount of CBDA 80% from total cannabinoids, using an approach of supercritical extraction with COwith the following parameters: pressure—465 bar, extraction temperature—70° C., process length—120 minutes.'}{'i': 'Cannabis sativa', 'b) decarboxylation of extract to produce CBD resin, at 160° C. for 6 hours ...

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13-05-2021 дата публикации

WHOLE GINSENG COMPOSITION USING GINSENG ROOTS, LEAVES AND BERRIES AND METHOD OF PREPARING THE SAME

Номер: US20210138010A1
Принадлежит:

Disclosed are a red ginseng and/or a red ginseng extract obtained by subjecting (raw) ginseng to ultrasonic treatment and ultrahigh-pressure treatment and then steaming and drying the ginseng, and a method of preparing the same. Also disclosed are a whole ginseng composition including the red ginseng extract prepared by the method, a ginseng leaf extract and a ginseng berry extract, and a method of preparing the same. Advantageously, the red ginseng and the red ginseng extract produced by ultrasonic treatment and ultrahigh-pressure treatment according to the present invention have a lower maximum stress than the conventional red ginseng concentrate in terms of physical properties, reduced inconvenience during ingestion and storage, and increased active ingredient contents. 1. A method of preparing red ginseng comprising:(a) subjecting ginseng (raw ginseng) to ultrasonic treatment and ultrahigh-pressure treatment; and(b) obtaining red ginseng by steaming and drying the ginseng.2. The method of preparing red ginseng of claim 1 , wherein the ultrasonic treatment in step (a) is carried out under the condition of 10 to 200 kHz for 5 minutes to 4 hours and the ultrahigh-pressure treatment in step (a) is carried out under the condition of 200 to 800 MPa for 20 seconds to 10 minutes.3. The method of preparing red ginseng of claim 1 , wherein the steaming in step (b) is carried out at a temperature of 90 to 100° C. for 1 to 5 hours and is repeated one or more times.49.-. (canceled)10. A whole ginseng composition comprising the red ginseng extract prepared by the method of claim 1 , a ginseng leaf extract and a ginseng berry extract.11. The whole ginseng composition of claim 10 , comprising 60 to 95% by weight of the red ginseng extract claim 10 , 3 to 25% by weight of the ginseng leaf extract and 2 to 15% by weight of the ginseng berry extract.12. The whole ginseng composition of claim 10 , wherein the ginseng leaf extract and the ginseng berry extract are obtained by a ...

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09-04-2020 дата публикации

Method for preparing fenugreek extract and pharmaceutical composition comprising fenugreek extract

Номер: US20200108112A1
Автор: Sih-Yu SHEN
Принадлежит: Prince Pharmaceutical Co Ltd

Provided is a method for preparing a fenugreek extract, including the steps of: (1) preparing a fenugreek plant tissue, soaking the fenugreek plant in water from 0.5 hour to 5 hours and between 25° C. and 100° C. for extraction, and (2) filtering the extracted fenugreek plant tissue to obtain the fenugreek extract. Also provided is an active substance that comprises the fenugreek extract obtained by the method. Also provided is a pharmaceutical composition for preventing or treating nonalcoholic fatty liver disease, which comprises the active substance and a pharmaceutically acceptable carrier.

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25-08-2022 дата публикации

NATURAL VANILLIN COMPOSITIONS

Номер: US20220264922A1
Автор: Garel Laurent
Принадлежит:

The present invention relates to natural vanillin compositions comprising at least one compound chosen from 4-((4-hydroxy-3-methoxybenzyl)oxy)-3-methoxybenzaldehyde and 4-hydroxy-3-(4-hydroxy-3-methoxybenzyl)-5-methoxybenzaldehyde. The invention also relates to a process for obtaining natural vanillin compositions according to the invention. 110-. (canceled)11. A composition comprising natural vanillin and further comprising at least one compound chosen from 4-((4-hydroxy-3-methoxybenzyl)oxy)-3-methoxybenzaldehyde and 4-hydroxy-3-(4-hydroxy-3-methoxybenzyl)-5-methoxybenzaldehyde , the composition exhibiting a natural vanillin titer of greater than or equal to 90%.12. The composition of claim 11 , further comprising at least one compound chosen from vanillyl alcohol claim 11 , vanillic acid claim 11 , acetovanillone claim 11 , guaiacol and vinylguaiacol claim 11 , preferably chosen from vanillyl alcohol claim 11 , vanillic acid and acetovanillone.13. The composition of claim 11 , wherein the natural vanillin titer is greater than 95%.14. The composition of claim 11 , wherein the content by weight of 4-((4-hydroxy-3-methoxybenzyl)oxy)-3-methoxybenzaldehyde claim 11 , relative to the total weight of the composition claim 11 , is less than or equal to 10 000 ppm and greater than or equal to 10 ppm.15. The composition of claim 11 , wherein the content by weight of 4-hydroxy-3-(4-hydroxy-3-methoxybenzyl)-5-methoxybenzaldehyde claim 11 , relative to the total weight of the composition claim 11 , is less than or equal to 5000 ppm and greater than or equal to 10 ppm.16. The composition of claim 11 , comprising a color of less than or equal to 400 Hazen.17. A process for preparing the composition of claim 11 , the process comprising a step (a) of fermenting ferulic acid and optionally a step (b) of purifying the natural vanillin composition obtained at the end of step (a).18. The process claim 17 , wherein step (b) is a step of evaporation in a wiped film evaporator or of ...

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25-08-2022 дата публикации

NANO-DISPERSION METHODS FOR CANNABIS EXTRACT

Номер: US20220265742A1
Принадлежит:

The present disclosure provides techniques for producing whey protein nano-emulsions from extracts. An emulsion prepared using an embodiment of a method of the invention can be subject to further processing with which to convert the emulsion (or a component thereof) into one or more consumables. 2. The method of claim 1 , wherein a means of producing the bio extract comprises one or both of a supercritical carbon dioxide bio-extraction and an organic solvent based extraction.3. (canceled)4. The method of claim 1 , wherein the oil comprises a food grade oil.5. (canceled)6. The method of claim 1 , further comprising decarboxylating the organic phase oil nano-emulsion prior to adding the organic phase oil nano-emulsion to the aqueous phase.79-. (canceled)10. The method of claim 6 , wherein the decarboxylated organic phase oil nano-emulsion is at least about 60% decarboxylated.11. (canceled)12. The method of claim 1 , wherein the bio extract is about 0.1% to about 20% of the course emulsion.13. (canceled)14. The method of claim 1 , wherein the adding the organic phase oil nano-emulsion is performed using an organic phase oil nano-emulsion to aqueous phase ratio selected from the group consisting of 1:1 claim 1 , 1:2 claim 1 , 1:3 claim 1 , 1:4 claim 1 , 1:5 claim 1 , 1:6 claim 1 , 1:7 claim 1 , 1:8 claim 1 , and 1:9.15. (canceled)16. The method of claim 1 , further comprising homogenizing the course emulsion to produce a homogenized course emulsion.1718-. (canceled)19. The method of claim 16 , further comprising producing a powder from the homogenized course emulsion.2025-. (canceled)26cannabis. The method of claim 1 , wherein the comprises hemp.27. (canceled)28. The method of claim 1 , wherein the bio extract comprises at least one of cannabinoids claim 1 , flavonoids claim 1 , and terpenoids.30. The method of claim 29 , wherein the producing of the bio extract comprises one or both of a supercritical carbon dioxide bio-extraction and an organic solvent based ...

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25-08-2022 дата публикации

PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING

Номер: US20220265744A1
Автор: Speier Gary J.
Принадлежит:

The present invention provides for methods of obtaining an extract of plant material as well as subsequent processing of the extract to provide a concentrate of . The present invention also provides for pharmaceutical dosage forms (e.g., oral thin films and transdermal patches) that include the concentrate (or extract) of , as well as methods of medical treatment that include administering the pharmaceutical dosage forms. 1Cannabis{'i': Cannabis', 'Cannabis, '(a) contacting plant material with a supercritical fluid solvent system, at a pressure between about 750 psi and 25,000 psi, and at a temperature between about −15° C. and 200° C., to provide an extract of ; and'}(b) removing the supercritical fluid solvent system from the extract;{'i': 'Cannabis', 'wherein the (a) contacting of the plant material with the supercritical fluid solvent system and the (b) removing the supercritical fluid solvent system, is carried out multiple times, such that the process is a fractional supercritical fluid extraction;'}{'i': 'Cannabis', 'wherein each contacting of the with a supercritical fluid solvent system independently occurs at a pressure between about 750 psi and 25,000 psi, and independently occurs at a temperature between about −15° C. and 200° C.'}. A process for obtaining a concentrate of , the process comprising: The medicinal and psychoactive properties of the plant have been known for centuries. At present, is not legally available in many States. However, there is growing pressure on politicians to legalize its use, especially for medicinal purposes.Evidence suggests that is a safe, versatile and potentially inexpensive drug. It has been reported as being beneficial to patients suffering from a wide range of symptoms experienced in connection with various, often very serious, medical conditions. For example, has been used to alleviate symptoms associated with cancer, anorexia, AIDS, chronic pain, spacicity, glaucoma, arthritis, migraine and many other illnesses.is ...

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25-08-2022 дата публикации

Methods of Extraction of Plant Materials and Extracts Obtained Using Supercritical Glycerin

Номер: US20220265745A1
Принадлежит:

A method for extracting bioactive compounds from plant materials using supercritical glycerin and at least one inert co-solvent that lowers the effective supercritical point of the supercritical glycerin to its boiling point, and the extracts obtained from the method. 1. A system for supercritical glycerin extraction of a composition of matter containing bioactive compounds comprising:a) at least one liquid glycerin reservoir;b) at least one heater connected to the liquid glycerin reservoir for converting the liquid glycerin from the liquid glycerin reservoir into glycerin vapor;c) at least one pressure regulator connected to the heater;d) at least one co-solvent gas reservoir;e) at least one condenser connected to the co-solvent gas reservoir;f) at least one pressure regulator connected to the condenser;g) a proportioning valve that receives the co-solvent gas and the glycerin vapor to form a mixture;h) an at least one additional heater connected to the proportioning valve to heat the mixture to form a supercritical mixture of co-solvent and glycerin;i) at least one extraction chamber containing the composition of matter for supercritical glycerin extraction connected to the additional heater; andj) at least one separator connected to the extraction chamber to separate gas co-solvent from the gas mixture comprising gaseous glycerin and gaseous co-solvent.2. The system of claim 1 , wherein the extraction process is automated.3. The system of claim 1 , wherein a plurality of separators are connected sequentially to the extraction chamber to separate selected bioactive compounds.4. A method for supercritical extraction of a composition of matter containing bioactive compounds comprising contacting a selected composition of matter which contain bioactive compounds that are soluble in supercritical glycerin claim 1 , with a supercritical mixture of glycerin and one or more non-reactive inert gas co-solvents with an effective supercritical point temperature below 301° ...

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25-08-2022 дата публикации

PREPARATION COMPRISING OMEGA-3 FATTY ACID SALTS AND EXTRACTS OF GUM RESINS FROM BOSWELLIA SPECIES

Номер: US20220265749A1
Принадлежит: EVONIK OPERATIONS GMBH

Preparations may include at least one extract of gum resins from species and at least one omega-3 fatty acid salt selected from eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Surprisingly, such combinations of extracts of gum resins from species and polyunsaturated fatty acid salt can cause a marked and unexpected increase in the biosynthesis of specialized pro-resolving mediators (SPM) in a synergistic manner, proposing benefit for resolution of inflammatory conditions. 1. A preparation , comprising{'i': Boswellia', 'Boswellia, 'an extract of one or more gum resins from species as a extract; and'}a polyunsaturated fatty acid salt comprising (i) an omega-3 fatty acid comprising eicosapentaenoic acid (EPA) and/or docosahexaenoic acid (DHA) and (ii) a basic amino acid.2Boswelliacomprises Boswellia serrata, Boswellia carterii, Boswellia papyrifera, Boswellia ameero, Boswellia bullata, Boswellia dalzielii, Boswellia dioscorides, Boswellia elongata, Boswellia frereana, Boswellia nana, Boswellia neglecta, Boswellia ogadensis, Boswellia pirottae, Boswellia popoviana, Boswellia rivae, Boswellia sacraBoswellia. The preparation of claim 1 , wherein the species claim 1 , and/or socotrana.3. The preparation of claim 1 , wherein the extract is prepared by hydro-distillation claim 1 , steam distillation claim 1 , extraction by percolation claim 1 , extraction under ultrasonic waves claim 1 , solvent extraction claim 1 , Soxhlet's extraction claim 1 , supercritical fluid extraction claim 1 , or membrane nanofiltration.4. The preparation of claim 1 , comprising a boswellic acid.5. The preparation of claim 1 , further comprising:acid resin,gum;tetratriterpene acid;Pentacyclic triterpene; incensole acetate;phellandrene;(+)-cis-olibanic acid; and/or(+)-trans-olibanic acid.6. The preparation of claim 1 , wherein the omega-3 fatty acid salts comprises an organic counter ion comprising lysine claim 1 , arginine claim 1 , ornithine claim 1 , and/or choline.7Boswellia. The ...

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25-08-2022 дата публикации

METHODS OF MODIFYING A NATURALLY OCCURRING CANNABIS RAW PLANT MATERIAL, A PURIFIED CANNABIS PRODUCT FROM A NATURALLY OCCURRING CANNABIS RAW PLANT MATERIAL, AND A MODIFIED CANNABIS PRODUCT FROM A NATURALLY OCCURRING CANNABIS RAW PLANT MATERIAL

Номер: US20220266168A1
Автор: Lombardi Vincent C.
Принадлежит: HIGH SIERRA TECHNOLOGIES, INC.

A method of modifying a naturally occurring raw plant material, a purified product from a naturally occurring raw plant material, and a modified product from a naturally occurring raw plant material. The method includes selectively extracting at least some volatile organic compounds from a naturally occurring raw plant material. At least some of a naturally occurring potential cannabinoid content in the raw plant material is retained after removal of the at least some of the volatile organic compounds as well as substantially all of the physical structure of the raw plant material. 1Cannabis. A method of modifying a naturally occurring raw plant material , the method comprising:{'i': 'Cannabis', 'selectively extracting at least some volatile organic compounds from a naturally occurring raw plant material,'}{'i': 'Cannabis', 'wherein at least some of a naturally occurring potential cannabinoid content in the raw plant material is retained after removal of the at least some of the volatile organic compounds.'}2Cannabis. The method of modifying a naturally occurring raw plant material according to claim 1 , wherein the at least some volatile organic compounds are selectively extracted by controlling a pressure in a variable-pressure steam extraction apparatus.3Cannabis. The method of modifying a naturally occurring raw plant material according to claim 2 , wherein reducing the pressure decreases the boiling point of the at least some volatile organic compounds in the variable-pressure steam extraction apparatus.4Cannabis. The method of modifying a naturally occurring raw plant material according to claim 2 , wherein increasing the pressure increases the boiling point of the at least some volatile organic compounds in the variable-pressure steam extraction apparatus.5Cannabis. The method of modifying a naturally occurring raw plant material according to claim 2 , wherein the pressure in the variable-pressure steam extraction apparatus is set to be in a range of 0.0001 ...

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12-05-2016 дата публикации

Use of instant asparagus powder in food, medicine and health food

Номер: US20160129067A1

Disclosed is use of an asparagus powder in medicines, food, and health foods for treatment of anxiety and depressive mental disorders, with active ingredients in the asparagus powder including: 15.0% or more of an asparagus saponin, 8% or more of a polysaccharide, 3.0% or more of a polyphenol, and 2.0% or more of a flavone.

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10-05-2018 дата публикации

NOVEL COMPOSITION OF NIGELLA SATIVASEEDS TO TREAT ANXIETY, STRESS AND SLEEP DISORDERS WITH SIGNIFICANT MEMORY ENHANCEMENT PROPERTIES AND A PROCESS FOR PRODUCING THE SAME

Номер: US20180125914A1
Принадлежит: AKAY FLAVOURS & AROMATICS PVT LTD.

The present invention relates to novel black cumin extract compositions and a green process for making the composition. The black cumin extract composition of the invention can be used to treat anxiety, sleep and stress disorders along with significant effect on memory enhancement. The composition is available in oil and powder forms. 1. A biologically active composition , comprising: black cumin seed extract in oil or powder form , wherein the black cumin seed extract further comprises thymoquinone , α-linoleic acid , and polyphenols.2. The composition of claim 1 , wherein the biologically active black cumin oil comprises thymoquinone in the range of 0.5-43% claim 1 , α-linoleic acid in the range of 45-60% claim 1 , and polyphenols in the range of 0.5 to 4%.3. The composition of claim 1 , wherein the biologically active black cumin powder comprises thymoquinone in the range of 0.5-8% claim 1 , α-linoleic acid in the range of 1-10% claim 1 , polyphenols in the range of 0.5 to 1.0 claim 1 , black cumin derived proteins in the range of 10-50% claim 1 , and cumin derived carbohydrates in the range of 20-70%.4. A method for treating humans with anxiety claim 1 , stress claim 1 , memory loss and sleep associated disorders claim 1 , comprising administering to the human a therapeutically effective amount of black cumin oil or powder composition in the range of 50-500 mg per day.5. The method of claim 4 , wherein the method provides an anxiolytic effect through(a) decreasing the expression in glutamate receptors subtypes NR2A and GluR2; and(b) increasing survival of ChAT expressing neuronal cells in the hippocampus.6. The method of claim 4 , wherein the method produces a memory effect through inhibiting acetylcholinesterase.7. The method of claim 4 , wherein the sleep associated disorders is selected from sleep disturbances and high sleep latency.8. The method of claim 4 , wherein the therapeutically effective amount contains not less than 5% thymoquinone and not less than ...

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03-06-2021 дата публикации

METHOD FOR CONDUCING CONCENTRATED CANNABIS OIL TO BE STABLE, EMULSIFIABLE AND FLAVORLESS FOR USE IN HOT BEVERAGES AND RESULTING POWDERIZED CANNABIS OIL

Номер: US20210161177A1
Принадлежит:

A method for producing powderized cannabis oil, powderized cannabis oil, and edible products and beverages comprising the powderized cannabis oil. Powderized cannabis oil contains cannabis oil and maltodextrin in a ratio of at least three grams of maltodextrin for every one-eighth of a gram of cannabis oil. Edible products and beverages incorporating the powderized cannabis oil are human-consumable products that contain an emulsified, tasteless, and odorless dose of cannabis oil providing CBD, THC and/or THCA. 1. An edible product or beverage comprising a powderized cannabis oil consisting essentially of cannabis oil and carboxymethyl cellulose in a ratio of at least three grams of carboxymethyl cellulose to every one-half of a gram of cannabis oil.2. The edible product or beverage of claim 1 , wherein the ratio of the carboxymethyl cellulose to the cannabis oil claim 1 , by weight claim 1 , is at least three grams of carboxymethyl cellulose to every one-eighth of a gram of cannabis oil.3. The edible product or beverage of claim 1 , wherein the ratio of the carboxymethyl cellulose to the cannabis oil claim 1 , by weight claim 1 , is between three grams of carboxymethyl cellulose for every one-eighth of a gram to one-half of a gram of cannabis oil.4. The edible product or beverage of claim 1 , comprising one or more of cannabidiol (CBD) claim 1 , tetrahydrocannabinol (THC) and tetrahydrocannabinolic acid (THCA).5. The edible product or beverage of claim 4 , comprising:(a) up to about 200 mg THC; and/or(b) up to about 200 mg CBD; and/or(c) up to about 200 mg THCA.6. The edible product or beverage of claim 5 , wherein the edible product is an artificial sweetener or sugar.7. The edible product or beverage of claim 6 , wherein the artificial sweetener or sugar is portioned to provide a dose of up to about 80 mg THC claim 6 , CBD and/or THCA per portion.8. The edible product or beverage of claim 5 , wherein the edible product is a beverage mix selected from coffee claim ...

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03-06-2021 дата публикации

CAFFEINE COMPOSITIONS AND METHODS OF USE

Номер: US20210161986A1
Принадлежит:

A pharmaceutical composition formulated for intranasal administration comprising a natural caffeine extract, a pharmaceutically acceptable excipient, a pharmaceutically acceptable aqueous carrier; and, optionally, additional caffeine, or a pharmaceutically acceptable salt, solvate, derivative or metabolite thereof. Methods of preparation and methods of use are also described. 1. A method of treating or preventing a craving for coffee in an individual , or treating or preventing caffeine withdrawal or a symptom of caffeine withdrawal in an individual , comprising administering to the individual via intranasal delivery an aqueous pharmaceutical composition comprising a natural caffeine extract and at least one pharmaceutically acceptable excipient.23-. (canceled)4. The method according to claim 1 , wherein the natural caffeine extract is coffee extract.5. The method according to claim 1 , wherein the method maintains a nil-by-mouth status.6. The method according to claim 1 , wherein the method is carried out prior to a medical procedure.7. The method according to claim 1 , wherein the composition further comprises caffeine or a pharmaceutically acceptable salt claim 1 , solvate claim 1 , derivative or metabolite thereof.8. The method according to claim 7 , wherein the composition comprises total caffeine in an amount of about 0.5 to 2.2% w/v9. The method according to claim 1 , wherein the composition is delivered by a nasal spray dispenser.10. The method according to claim 1 , wherein the dispenser is a metered dose device.11. The method according to claim 10 , whereinthe dispenser is configured to dispense a total volume of the composition of 0.05-0.2 mL per actuation.12. The method according to claim 11 , wherein the dispenser delivers approximately 2 mg of caffeine per 0.1 mL actuation.13. A pharmaceutical composition formulated for nasal administration comprising:a natural caffeine extract;at least one pharmaceutically acceptable excipient;a pharmaceutically ...

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18-05-2017 дата публикации

THERAPEUTIC COMPOSITIONS COMPRISING HERBAL EXTRACTS AND ESSENTIAL OILS FOR SMOKING AND VAPORIZATION

Номер: US20170136076A1
Принадлежит:

The present invention discloses therapeutic compositions comprising herbal extracts and essential oils for smoking and vaporization useful in the treatment of various symptoms and diseases. More particularly the invention relates to compositions comprising herbal extracts and essential oils capable of providing therapeutic benefits, which helps to improve conditions like cough, cold, pain, energy, relaxation, calmness, digestion, immune system disorders and neurological disorders etc. The invention further relates to methods for treating the same using the compositions of the invention. The invention also discloses method of formulating a blend of herbal COextracts and essential oils without the use of any type of synthetic carriers or residual solvent or synthetic chemicals, thus improving quality, safety and efficacy. 1. A therapeutic herbal composition for smoking and vaporization comprising one or more herbal COextracts in an amount of 1 to 20%; one or more COessential oils and/or essential steam distilled oils in an amount of 1 to 20% together with one or more fixed oils selected from the group consisting of flax seed oil , sesame seed oil , castor oil , sunflower oil , soyabean oil , safflower oil , corn oil , hemp oil , palm oil , and peanut oil , in an amount of 60 to 98% , wherein , the composition is essentially devoid of chemical carriers viz. , PEG , PG and Glycerin , for use in treating different disease conditions like cough , cold , pain , energy , relaxation , calmness , digestion , immune system disorder and neurological disorders.2Cinnamomum zeylanicumElettaria cardamomumCrocus sativusSantalum albumOcimum sanctumCurcuma longaZingiber officinaleApium graveolensMentha piperitaCinnamomum camphoraCelastrus paniculatusBoswellia serrataMyristicaValeriana WallichiiNardostachys jatamansi. The therapeutic herbal composition for smoking and vaporization according to claim 1 , wherein the one or more essential oils are selected from the group consisting of ...

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18-05-2017 дата публикации

PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING SENILE DEMENTIA AND PREPARATION METHOD THEREOF

Номер: US20170136083A1
Принадлежит:

The present disclosure relates to a pharmaceutical composition for preventing and treating senile dementia and preparation method thereof. The active ingredients of the pharmaceutical composition are prepared from raw medicinal materials comprising 20-50 parts by weight of Folium and 15-55 parts by weight of ; or from raw medicinal materials comprising 20-50 parts by weight of Folium, 15-55 parts by weight of and 10-55 parts by weight of , or from raw medicinal materials 20-50 parts by weight of Folium, 15-50 parts by weight of , 15-50 parts by weight of and 6-15 parts by weight of Rhizoma. 1EpimediiPoria, PoriaPolyporus.. A pharmaceutical composition for treating or preventing senile dementia , the composition comprising active ingredients , wherein the active ingredients of the pharmaceutical composition are prepared from raw medicinal materials comprising 20-50 parts by weight of Folium and 15-55 parts by weight of cum Radix Pini , or2EpimediiPoria, PoriaPolyporusAcanthopanax. AcanthopanacisAcanthopanacis folium.. The pharmaceutical composition for treating or preventing senile dementia as claimed in claim 1 , wherein the active ingredients of the pharmaceutical composition are prepared from raw medicinal materials comprising 20-50 parts by weight of Folium claim 1 , 15-55 parts by weight of cum Radix Pini claim 1 , or and 10-55 parts by weight of cortex claim 1 , or3EpimediiPoriaAcanthopanax . AcanthopanacisAcanthopanacis folium.. The pharmaceutical composition for treating or preventing senile dementia as claimed in claim 2 , wherein the active ingredients of the pharmaceutical composition are prepared from raw medicinal materials comprising 20-30 parts by weight of Folium claim 2 , 20-45 parts by weight of and 20-55 parts by weight of cortex claim 2 , or4EpimediiPoria, PoriaPolyporusAcanthopanax, AcanthopanacisAcanthopanacis folium.. The pharmaceutical composition for treating or preventing senile dementia as claimed in claim 3 , wherein the active ingredients ...

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08-09-2022 дата публикации

METHOD FOR EXTRACTION

Номер: US20220280586A1
Автор: WOERLEE Geert Feye
Принадлежит: FOLIUM BIOSCIENCES EUROPE B.V.

The invention provides a method for producing a composition of lipophilic compounds using extraction using liquid carbon dioxide or supercritical carbon dioxide as an extractant, said method comprising providing at least one first matrix, selecting at least one second matrix comprising at least one terpene or at least one flavonoid compound that is detectable in said composition of lipophilic compounds, for providing a fingerprint in said composition of lipophilic compounds, said fingerprint at least defined by said at least one terpene or at least one flavonoid compound. 1. A method for fingerprinting a composition of lipophilic compounds obtained by extraction and separation using liquid carbon dioxide or supercritical carbon dioxide for extraction and separation , wherein the method is for a purpose selected from for marking an individual batch , for marking an origin of the composition , for marking a date of production , and a combination thereof , said method comprising:providing an amount of at least one first matrix of plant-based material comprising a mixture of lipophilic compounds to be extracted and separated, said mixture of lipophilic compound comprising at least two compounds selected from at least one terpene compound, at least one flavonoid compound, and a combination thereof;selecting an extraction temperature between 0° C. and 100° C. and an extraction pressure between 10 and 1000 bar for extracting said at least part of said mixture of lipophilic compounds from said first matrix;defining a separation pressure between 10 and 1000 bar and a separation temperature between 0° C. and 100° C. for providing a fingerprint of said mixture comprising said at least two compounds selected from at least one terpene compound, at least one flavonoid compound, and a combination thereof;extracting said first matrix using said extractant, at said selected extraction pressure and said extraction temperature, providing an extract in said extractant;separating said ...

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08-09-2022 дата публикации

MEDICAMENT FOR TREATING STROKE CAUSED BY DEEP FUNGAL INFECTIONS

Номер: US20220280588A1
Автор: Xiao Mingchun
Принадлежит:

Use of addition and subtraction of the Banxia Baizhu Tianma Decoction in preparation of medicines or health products for treating strokes caused by deep fungal infections. The present invention relates to the field of medical and health care, and specifically relates to use of chemical ingredients, i.e. alkaloids and volatile oils contained in plant raw materials such as , fresh orange peel and Liquorice to prepare drugs or health products for treating strokes caused by deep fungal infections. 1Gastrodia elataPinellia ternataAtractylodes macrocephalaPoria cocosGastrodia elataPinellia ternataAtractylodes macrocephalaPoria cocosGastrodia elataPinellia ternataAtractylodes macrocephalaPoria cocosGastrodia elataPinellia ternataAtractylodes macrocephalaPoria cocos. A medicine for treating strokes caused by deep fungal infections , characterized in that the active pharmaceutical ingredients of the medicine comprise alkaloids and/or volatile oils extracted from , alkaloids and/or volatile oils extracted from , alkaloids and/or volatile oils extracted from , alkaloids and/or volatile oils extracted from , alkaloids and/or volatile oils extracted from fresh orange peel , and alkaloids and/or volatile oils extracted from Liquorice; methods for preparing the medicine include: taking alkaloids of , alkaloids of , alkaloids of , alkaloids of , alkaloids of fresh orange peel and alkaloids of Liquorice and mixing them in a certain proportion; adding various conventional excipients required to prepare different dosage forms thereto; and preparing pharmaceutically acceptable dosage forms; taking volatile oils of , volatile oils of , volatile oils of , volatile oils of , volatile oils of fresh orange peel and volatile oils of Liquorice and mixing them in a certain proportion; adding various conventional excipients required to prepare different dosage forms thereto; and preparing pharmaceutically acceptable dosage forms; taking alkaloids and volatile oils of , alkaloids and volatile ...

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09-05-2019 дата публикации

Cultivation, Processing, and Synthesis of Cannabidiols

Номер: US20190134122A1
Принадлежит:

The process described below is a method of making tinctures starting with extraction of a full spectrum oil from a biomass, then activating the cannabinoids in the full spectrum oil, finally formulating tinctures using the activated full spectrum oil. 1. A process for the removal of cannabidiols from industrial hemp comprising the steps of:grinding the industrial hemp, resulting in ground industrial hemp; placing the ground industrial hemp into a chamber of a supercritical fluid extractor;', 'pressurizing the chamber using a supercritical fluid;', 'allowing the mixture of supercritical fluid and ground industrial hemp to soak for a period of time;', 'opening a drain to allow the supercritical fluid to pass into a vessel, the supercritical fluid now containing extracted oil;', 'allowing the supercritical fluid to evaporate, leaving behind the extracted oil in the form of a resin;, 'extracting cannabinoids from the ground industrial hemp comprising the steps of filling a flask with resin;', 'heating the resin to 240 degrees Fahrenheit;', 'stirring the resin until no bubbles of supercritical fluid rise to the surface of the resin;', 'allowing the resin to cool, resulting in a full-spectrum oil;, 'purging the resin of carbon dioxide comprising the steps of mixing the full-spectrum oil with ethanol at a ratio of one part full-spectrum oil to three parts ethanol to create an oil-ethanol mixture;', 'heating the oil-ethanol mixture to evaporate the excess ethanol;', 'cooling the oil-ethanol mixture to 32 degrees Fahrenheit or below and holding for between 24 and 48 hours, during which time fatty and waxy materials precipitate out of the full-spectrum oil;', 'filtering the oil-ethanol mixture to remove the precipitated fatty and waxy materials, resulting in a winterized oil;, 'winterizing the full spectrum oil comprising the steps of heating the winterized oil to a temperature of 212 degrees Fahrenheit;', 'applying a vacuum to the winterized oil of between minus 8 to minus ...

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02-06-2016 дата публикации

Formulations containing extracts of echinacea angustifolia and zingiber officinale which are useful in reducing inflammation and peripheral pain

Номер: US20160151441A1
Принадлежит: Indena SpA

Disclosed is a combination of lipophilic extracts of Zingiber officinale and Echinacea angustifolia for the treatment of itching, peripheral pain, superficial and deep inflammatory and painful states, pain associated with muscle spasms, herpes pain, and radiodermatitis caused by oncological radiotherapy, with or without fungal or bacterial infections.

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16-05-2019 дата публикации

PHYTOCANNABINOID TOPICAL COMPOSITIONS FOR RELEIVING PAIN

Номер: US20190142888A1
Автор: MOJSA Agnes V.
Принадлежит:

A topical composition for pain relief comprising phytocannabinoids and a carrier vehicle for the phytocannabinoids, which include tetrahydrocannabinol THC and cannabidiol CBD present in amounts up to 25%, delivered to a user's skin and/or lips to alleviate pain. 1. A topical composition for pain relief comprising phytocannabinoids and a carrier vehicle for said phytocannabinoids; wherein said composition is delivered to a user's skin and/or lips to alleviate pain.2. The composition according to claim 1 , wherein said phytocannabinoids are from the group consisting of cannabidiol (CBD) claim 1 , cannabigerol (CBG) claim 1 , and tetrahydrocannabinol (THC).3. The composition according to claim 1 , wherein said phytocannabinoids are present in a therapeutic amount.4. The compositions according to claim 1 , wherein said carrier vehicle is a balm.5. The composition according to claim 1 , wherein said carrier vehicle is a cream.6. The composition according to claim 1 , wherein said carrier vehicle is an ointment.7. The composition according to claim 1 , wherein said phytocannabinoids are extracted from a powder made by grinding the shake claim 1 , flower claim 1 , buds claim 1 , small and large leaves of the marijuana plant.8. The composition according to claim 1 , wherein said carrier vehicle is up to 25% of shea butter.9. The composition according to claim 1 , wherein said carrier vehicle is up to 25% of beeswax.10. The composition according to claim 1 , further including essential oils and/or arnica oil.11. The composition according to claim 1 , wherein the resulting composition has tetrahydrocannabinol (THC) present in an amount up to 25%.12. The composition according to claim 1 , wherein the resulting composition has cannabidiol (CBD) present in an amount up to 25%.13. The composition according to claim 1 , wherein the resulting composition has cannabigerol (CBG) and other cannabinoids present in trace amounts up to 1%.14. The composition according to claim 1 , ...

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31-05-2018 дата публикации

Method for preparation of a cannabinoid extract from hemp

Номер: US20180147247A1
Автор: Ervin Milenov IVANOV
Принадлежит: &#34;Pobelch - Gle&#34; Ood

The invention relates to a method for extraction and separation of cannabinoids from industrial hemp, designed for medicinal purposes, and also the preparation of an extract, not containing tetrahydrocannabinol, and the preparation of maximum refined individual cannabinoids. The advantage of the method according to the invention consists in the preparation of an extract from hemp, which contains at a high percentage medically useful cannabinoids and doesn't contain undesirable admixtures and tetrahydrocannabinol, so that it can be used without any restrictions as a pharmaceutical. Moreover, the method allows the possibility of separation, if required, into individual useful cannabinoids as pure compounds, in ecological terms, without environmental pollution, as it is according to the most synthetic methods. The possibility of producing pure compounds represents a great contribution to the research of substances, related to a concrete medical application and the preparation of various combinations thereof, with the objective of expansion the field of application. The method is also cost-effective. The method consists in that the extract, obtained in accordance with various methods, undergoes a centrifugal countercurrent liquid-liquid chromatography, as the operation includes a centrifugation of solvents and the extract, obtained during the previous operations; the solvents form two phases, the phase, which the extract is dissolved in, is mobile, and the other one is stationary, whereby the mobile phase passes through the stationary phase, wherein several amounts of the components of the extract content are captured; this passing of the mobile phase through the stationary phase is repeated many times, until separation of the desired substances, which are analyzed in a familiar way, whereby as stationary phase solvents are used, which are selected from the group of straight-chain and branched-chain hydrocarbons, produced from crude oil, straight-chain and/or ...

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31-05-2018 дата публикации

PHARMACEUTICAL COMPOSITION FOR TREATING ECZEMA AND METHOD FOR PREPARATION THEREOF

Номер: US20180147249A1
Автор: YU Luping
Принадлежит:

A pharmaceutical composition for treating eczema is disclosed. The pharmaceutical composition includes, by weight, 2 to 6 parts of Dried Rhizoma Zingiberis Officinalis, 2 to 6 parts of Paeonia Lactiflora, 1 to 4 parts of Fructus Amomi, 0.5 to 3 parts of Semen Alpiniae Katsumadai, 0.5 to 3 parts of Inula helenium, 0.5 to 3 parts of Radix Et Rhizoma Rhei and 0.5 to 3 parts of Rhizoma Dioscoreae. The components of the pharmaceutical composition synergistically cooperate to clear and disinhibit the liver and gallbladder and clear away damp heat from the body. The pharmaceutical composition can be used to treat skin eczema symptoms caused by metabolic disorders of the liver and gallbladder functions. A method for preparing the pharmaceutical composition is also disclosed. 1. A pharmaceutical composition for treating eczema , comprising , by weight , 2 to 6 parts of Dried Rhizoma Zingiberis Officinalis , 2 to 6 parts of Paeonia Lactiflora , 1 to 4 parts of Fructus Amomi , 0.5 to 3 parts of Semen Alpiniae Katsumadai , 0.5 to 3 parts of Inula helenium , 0.5 to 3 parts of Radix Et Rhizoma Rhei and 0.5 to 3 parts of Rhizoma Dioscoreae.2. The pharmaceutical composition for treating eczema according to claim 1 , comprising claim 1 , by weight claim 1 , 2 to 4 parts of Dried Rhizoma Zingiberis Officinalis claim 1 , 2 to 4 parts of Paeonia Lactiflora claim 1 , 1 to 3 parts of Fructus Amomi claim 1 , 0.5 to 2 parts of Semen Alpiniae Katsumadai claim 1 , 0.5 to 2 parts of Inula helenium claim 1 , 0.5 to 2 parts of Radix Et Rhizoma Rhei and 0.5 to 2 parts of Rhizoma Dioscoreae.3. The pharmaceutical composition for treating eczema according to claim 2 , comprising claim 2 , by weight claim 2 , 3 parts of Dried Rhizoma Zingiberis Officinalis claim 2 , 3 parts of Paeonia Lactiflora claim 2 , 2 parts of Fructus Amomi claim 2 , 1 part of Semen Alpiniae Katsumadai claim 2 , 1 part of Inula helenium claim 2 , 1 part of Radix Et Rhizoma Rhei and 1 part of Rhizoma Dioscoreae.4. The ...

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17-06-2021 дата публикации

FINE BAMBOO POWDER AND PREPARATION METHOD THEREFOR AND USE THEREOF

Номер: US20210177927A1
Принадлежит:

A MATZHU is prepared by using leaves of Gramineae (Graminae) and Bambusoideae plant as raw materials. The MATZHU has a stable emerald color and an average powder particle size of 800 to 10,000 meshes. The MATZHU also has a total amount of dietary fiber of ≥60%, a content of lignin of ≥20% and a content of minerals of ≥7%. The MATZHU includes at least three or more bamboo leaf characteristic components, such as orientin, isoorientin, vitexin, isovitexin, adenosine, δ-hydroxylysine and p-coumaric acid. The method for the MATZHU preparation includes, in turn, performing blanching and color protection, drying and superfine grinding the raw materials. By utilizing the thermal stability and the light stability of the MATZHU, the MATZHU may be used as a raw food material, a functional ingredient, or a dietary supplement. 117-. (canceled)18. A method for preparing MATZHU , comprising the following steps:raw materials are subjected to blanching and color protection, and dried and superfine grinded in turn to obtain the MATZHU having an average particle size of 1000-10,000 meshes;the raw materials are leaves of Gramineae (Graminae) and Bambusoideae plant;the blanching and color protection step comprises: putting bamboo leaves as raw materials into a color-protecting solution with a temperature of 85 to 95° C., taking out after soaking for 30 to 90 seconds, and draining;the color-protecting solution used in the blanching and color protection is a zinc sulfate aqueous solution or a zinc gluconate aqueous solution or a combination thereof with a concentration of 0.5 to 2.0 g/100 mL.19. The method of claim 18 , wherein a material-to-liquid ratio of the bamboo leaf and the color protection liquid is 1 g:50-100 mL.20. The method of claim 18 , wherein the drying is drying the leaves after blanching and color protection to a moisture content of ≤11%;the drying uses at least one of hot air drying, microwave drying, vacuum drying and freeze drying.21. The method of claim 18 , wherein ...

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09-06-2016 дата публикации

MEDICAL CANNABIS LOZENGES AND COMPOSITIONS THEREOF

Номер: US20160158298A1
Автор: KOLSKY JEFFREY A.
Принадлежит:

A method for optimizing the therapeutic effects provided by CBD on the one hand, and the psychoactive effects provided by THC on the other hand, in a sublingual medicament, the method includes the steps of obtaining a concentrated extract of in which the concentration of CBD is known and the concentration of THC is known, formulating a hydrophilic mixture containing ingredients such as sugar, corn syrup, xylitol, purified water, organic flavorings, coconut oil, and concentrated extract of , wherein the amount of CBD is as high as possible and where the amount of THC is precisely controlled, forming lozenges, and administering the medicament. 1cannabis sativacannabis indica. A lozenge consisting essentially of heat carboxylated CO2-extracted oil , heat carboxylated CO2-extracted oil , and xylitol , wherein the sativa oil and indica oil contain a predetermined weight of CBD and a predetermined weight of THC.2. The lozenge of having a mass of between 2 grams and 15 grams.3. The lozenge of containing a minimum of 25 mg of CBD.4. The lozenge of containing a maximum of 40 mg of THC.5. The lozenge of further consisting essentially of an ingredient selected from the group consisting of sugar claim 1 , corn syrup claim 1 , flavorings claim 1 , coloring agents claim 1 , coconut oil claim 1 , purified water and mixtures thereof.6. A method for minimizing the psychoactive effects of THC in a therapeutic treatment of a human patient claim 1 , the method consisting essentially of:{'i': cannabis sativa', 'cannabis indica, 'a) formulating a lozenge consisting essentially of heat carboxylated CO2-extracted oil, heat carboxylated CO2-extracted oil, and xylitol, wherein the sativa oil and indica oil contain as much CBD as possible and as little THC as possible; and'}{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'b) administering the lozenge of sublingually to a human until the lozenge is dissolved in the human, thereby minimizing the psychoactive effects of THC on the patient.'}7. ...

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07-06-2018 дата публикации

SYSTEMS AND METHODS FOR EXTRACTION OF NATURAL PRODUCTS

Номер: US20180153948A1
Автор: Murphy Randall B.
Принадлежит:

Described herein, inter alia, are processes, methods, and compositions useful for the extraction of natural products from source materials. 1. A method of extracting a natural organic compound from a natural material , said method comprising contacting said natural material with an extraction fluid thereby extracting said natural organic compound from said natural material into said extraction fluid to form an extracted fluid solution , wherein said extraction fluid comprises a fluorophilic compound and a hydrofluorocarbon.2. The method of claim 1 , wherein the natural material is a material derived from a plant claim 1 , an animal claim 1 , a fungi claim 1 , a bacteria or a virus.3Piper methysticum, CannabisSalviaBanisteriopsis caapi, Psychotria viridisDiplopterys cabrerana, Peganum harmala, Humulus lupulus. The method of claim 2 , wherein the plant is spp. claim 2 , spp. claim 2 , (chacruna) claim 2 , or mixture thereof.4Cannabis Sativa.. The method of claim 2 , wherein the plant is5. The method of one of claims 1 , wherein the natural organic compound is a biologically active organic compound claims 1 , an aromatic compound claims 1 , or forms part of an aromatic oil or essential oil.6. The method of one of claims 1 , wherein the natural organic compound is caffeine claims 1 , a terpene claims 1 , a humulone claims 1 , a lupulone claims 1 , a myrcene claims 1 , a humulene claims 1 , a caryophyllene claims 1 , an alkaloid claims 1 , a flavonoid claims 1 , a cannabinoid claims 1 , menthol claims 1 , capsaicin claims 1 , anise claims 1 , camphor claims 1 , xanthohumol claims 1 , 8-prenylnaringenin claims 1 , isoxanthohumol claims 1 , a prenylflavonoid claims 1 , a kavalactone claims 1 , a salvorin claims 1 , a cannabinoid claims 1 , tetrahydrocannabinol claims 1 , cannabidiol claims 1 , or cannabinol.7. The method of one of claims 1 , wherein at least 5000 g of said natural organic compound is present in said extracted fluid solution.8. The method of one of claims 1 ...

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22-09-2022 дата публикации

Swertia chirata extract and cosmetic compositions comprising same

Номер: US20220296497A1
Принадлежит: Chanel Parfums Beaute SAS

A Swertia chirata extract obtained by extracting with supercritical CO 2 an alcoholic extract of Swertia chirata , and to a cosmetic composition including such an extract having in particular an anti-ageing effect for the skin. Also, administering such an extract in a cosmetic method for preventing and/or reducing skin ageing and a cosmetic method for hydrating the skin and/or improving the barrier function of the skin

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