НОВЫЕ СПОСОБЫ И КОМПОЗИЦИИ ДЛЯ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЯ

... 1. Способ получения водной терапевтической композиции, включающий: объединение водно-спиртовых травяных экстрактов Sambucus nigra, Echinacea purpurea и Centella asiatica с водой с получением водной смеси;объединение водной смеси со спиртом с получением спиртовой смеси, имеющей концентрацию спирта более 50%;отделение нерастворимых материалов и спирта от спиртовой смеси с получением водной терапевтической композиции.2. Способ по п. 1, отличающийся тем, что спиртовая смесь содержит примерно 70% спирта.3. Способ по п. 1, отличающийся тем, что водную терапевтическую композицию дополнительно сушат с получением высушенной терапевтической композиции.4. Способ по п. 1, отличающийся тем, что спирт представляет собой этанол.5. Способ по п. 1, отличающийся тем, что нерастворимые материалы отделяют от спиртовой смеси с применением центрифугирования, фильтрования или осаждения.6. Способ по п. 1, отличающийся тем, что спирт отделяют от спиртовой смеси с применением вакуума.7. Способ по п. 3, отличающийся ...

ВОДА, ОБОГАЩЕННАЯ ФИТОХИМИЧЕСКИМИ ВЕЩЕСТВАМИ

Изобретение относится к воде и напиткам, именно к питьевым жидкостям, обогащенным фитохимическими веществами. Способ характеризуется тем, что он предусматривает получение экстракционной жидкости путем помещения надземных частей растения или облиственных побегов Bacopa, Centella или их комбинации в жидкость с рН, равным 5,5 и выше, и содержащей минералы и минеральные соли. Причем последние представляют собой по крайней мере натрий, кальций и калий и их соли. Хранят полученную экстракционную жидкость при температуре около 17°С в течение по крайней мере 2-х недель. Надземные части растения или облиственных побегов Bacopa, Centella или их комбинации добавляют в жидкость в количестве от 1 до 4 г на 100 мл. При этом в экстракционную жидкость из Bacopa, Centella или их комбинации высвобождаются соответственно бакозид А3, содержание которого составляет от 0,43 до 0,56 мг, бакопазид 11 - от 2 до 2,43 мг, бакопазид Х – от 0,32 до 0,81мг и бакопасапонин С – от 0,72 до 0,96 мг. В экстракционную жидкость ...

PROCEDURE FOR ISOLATION OF 14-B HYDRAULIC XY 10 THE ACETYL BACCATIN III

PHARMACEUTICAL COMPOSITION FOR TREATMENT OF MENOPAUSAL SYNDROME AND PREPARATION METHOD THEREOF

Abstract Disclosed is a pharmaceutical composition for the treatment of Menopausal Syndrome, wherein the pharmaceutical composition is consisted of the following herbs in weight parts: 5 1-3 parts Ramulus Cinnamomi, 0.5-2 parts Rhizoma Zingiberis, 2-4 parts Fructus Schisandrae Chinensis, 2-4 parts Flos Inulae, 3.5-5 parts Herba Lophatheri, 2-4 parts Cortex Moutan Radicis, 0.5-2 parts Fructus Jujubae, 2-4 parts Semen Ziziphi Spinosae, 2-4 parts Fructus Corni, 2-4 parts Radix Rehmanniae Recens, 2-4 parts Radix Codonopsis, and 0.5-2 parts Fructus Gardeniae. All herbs of the composition have synergistic effects to tonify liver and 10 supplement qi, nourish blood and tranquilize mind, clear deficient heat, and relieve restlessness. This invention also discloses a method for preparing the pharmaceutical composition for the treatment of Menopausal Syndrome, which is easy to implement, simple, safe and reliable, and suitable for industrial scale production.

Extraction of polyphenolic compounds from pomace

Methods of extraction of one or more polyphenolic compounds from pomace are described. The invention also provides uses of the extracts in the fortification of fruit juice, vegetable juice and foods, and as an antioxidant, an anti-inflammatory and an antifungal.

METHODS OF IDENTIFYING AND QUANTIFYING SPHINGOLIPIDS

The present invention relates to a method of identifying and preferably quantifying at least one sphingolipid, in particular the sphingolipid portion in wild-type Cordyceps or Cordyceps derivates. A further aspect relates to a method of identifying wild-type Cordyceps in a Cordyceps sample as well as for identifying Cordyceps derivates in a Cordyceps sample. The methods of the present invention, thus, allow for determining the quality and safety of Cordyceps products and for advantageously differentiating between wild-type Cordyceps and Cordyceps derivates via the ratio and/or presence of certain sphingolipids especially suitable as markers. Wild-type Cordyceps Wild-type Cordyceps Wild-type Cordyceps Cephalosporium Hirsutella sinensis Cordyceps sinensis sinensis _6 -2E5-1 -5 5 15 2S -16 -6 -%24 0 0 6 10 16 PLS . Pts 1 PLS Wild-type Cordyceps Wild-type Cordyceps Mortierella SP Gliocadium roseum *4 4 [ Fig. 6B ...

Desmodium styracifolium (Osb.) Merr. flavonoids capsule, method of preparing same, and application thereof

A Desmodium styracifolium (Osb.) Merr. flavonoids capsule, a method of preparing same, and use thereof. The Desmodium styracifolium (Osb.) Merr. flavonoids capsule comprises: Desmodium styracifolium (Osb.) Merr. flavonoids, being alcohol extract of Desmodium styracifolium (Osb.) Merr.; and a pharmaceutically acceptable excipient. The capsule is used for treating urinary tract calculi.

Phytochemical enhanced water

A method and formulation for fluids, such as drinking water, containing plant phytochemicals are disclosed. Some plants can survive in water without a root system, and the formulation includes fluid, such as water, with one or more of the plants maintained in the fluid. Cold storage resulted in enhanced production and excretion of phytochemicals from the plants into the fluid, including bacosides and bacopasides. These phytochemicals have been shown to exhibit antioxidant properties, promote memory and provide additional health benefits, as well as replace bottled water or other fluids as a means to ensure proper hydration. The fluids are useful for enhancing alertness.

A Formula of a Traditional Chinese Medicine Bacteriostatic Disinfectant and Preparation Method Thereof

The invention discloses a formula of a traditional Chinese medicine bacteriostatic disinfectant and a preparation method thereof, and relates to the technical field of traditional Chinese medicine. The formula raw materials of the traditional Chinese medicine compound bacteriostatic preparation comprise Radix Paeoniae Alba in Bozhou, Senecio scandens, golden-and-silver honeysuckle, Bo-Chrysanthemum and Mentha canadensis Linnaeus. The traditional Chinese medicine bacteriostatic preparation has a reasonable formula. It can effectively and quickly achieve bacteriostatic disinfection and sterilization effects. It also can be used for sterilization and disinfection for skin, mucous membrane, epidemic prevention and the like. The preparation method comprises the following steps. Decocting Radix Paeoniae Alba, Senecio scandens, golden-and-silver honeysuckle, Bo-Chrysanthemum and Mentha canadensis Linnaeus to obtain decoction liquid. Cooling the liquid to below 40°C, standing, filtering with membrane ...

PROCESS FOR REMOVING PESTICIDES FROM GINKGO BILOBA EXTRACTS, AND EXTRACTS OBTAINABLE BY SAID PROCESS

Process for removing pesticides from Ginkgo biloba extracts, which involves submitting an extract obtained by conventional methods to the following steps: a. Liquid-liquid extraction of the extract to obtain a medium polarity fraction containing ginkgo terpenes and pesticides not removable with hexane, and a high polarity fraction containing ginkgo flavone glycosides; b. crystallisation from the medium polarity fraction obtained at step a) to give an intermediate with a ginkgolide content of not less than 50%; c. crystallisation from the residual solution obtained at step b) to give an intermediate with a bilobalide content of not less than 50%; d. mixing of the high polarity fraction obtained at step a) with the ginkgo terpene intermediate and the bilobalide intermediate obtained at steps b) and c).

GINKGO BILOBA KETONE ESTER TABLET AND PREPARATION METHOD THEREOF

Provided are a ginkgo keto ester tablet, preparation method therefor, and use thereof. The ginkgo keto ester tablet is prepared by mixing a raw material of ginkgo keto ester and auxiliary materials. On the basis that the total weight of the ginkgo keto ester tablet is 0.25-0.26 g, the following conditions are met: the content of rutin is less than or equal to 1.60 mg per tablet; the content of rutinoside is less than or equal to 0.160 mg per tablet; the content of bilobalide is 1.04-2.08 mg per tablet; the content of ginkgolide J is 0.04-0.2 mg per tablet; the content of alcohol residue is less than or equal to 0.2 mg per tablet; the content of biflavone is less than or equal to 0.008 mg per tablet; and the contents of genistin and ginkgolide M are both 0.

PROCESS FOR THE PREPARATION OF POWDER COMPOSITIONS

The present invention relates to a process for the preparation of powder compositions comprising a lipophilic extract of Echinacea spp., a lipophilic extract of Zingiber officinale and phospholipids. The invention also relates to powder compositions obtainable by the process of the invention and pharmaceutical, nutraceutical and cosmetic formulations comprising said compositions. The invention regards the use of the powder compositions and formulations thereof in the prevention and/or treatment of inflammatory and painful states.

COMPOSITIONS, METHODS, AND MEDICAL COMPOSITIONS FOR TREATMENT OF AND MAINTAINING THE HEALTH OF THE LIVER

Compositions and methods for treatment of and maintaining the health of the liver are disclosed that include a mixture of plant extracts, wherein the plant extracts comprise at least one Artemisia extract, at least one Aloe gel powder, and at least one Schizandra extract. Compositions and methods for treatment of and maintaining the health of the liver are disclosed that include a mixture of plant extracts, wherein the plant extracts comprise at least one Artemisia extract enriched for at least one polymer or biopolymer, at least one Aloe gel powder enriched for at least one chromone, and at least one Schizandra extract enriched for at least one lignan and organic acid.

ANTIHYPERTENSIVE AGENT

Provided is a blood pressure-lowering agent that is safe and has a relaxing effect. The active ingredient of the blood pressure-lowering agent is S-1-propenyl cysteine or a salt thereof.

PHARMACEUTICAL COMPOSITION FOR TREATMENT OF DEPRESSION AND PREPARATION METHOD THEREOF

Disclosed is a pharmaceutical composition for the treatment of depression, wherein the pharmaceutical composition is comprised of the following herbs in weight parts: 2-10 parts Ramulus Cinnamomi, 2-10 parts Rhizoma Zingiberis, 2-10 parts Fructus Schisandrae Chinensis, 2-8 parts Semen Ziziphi Spinosae, 2-8 parts Radix Codonopsis, 1-3 parts Rhizoma Dioscoreae, 0.5-2.5 parts Flos Inulae, 1-3 parts Caulis Bambusae in Taenia, 1-3 parts Fructus Trichosanthis, 1.5-4 parts Caulis Polygoni Multiflori, 1.5-4 parts Radix Ophiopogonis, 2-8 parts Radix Rehmanniae, 1.5-4 parts Cortex Moutan Radicis, 0.5-2.5 parts Fructus Gardeniae, 0.5-2.5 parts Herba Lophatheri, and 0.2-1.5 parts Folium Sennae. Also disclosed is a method for preparing the pharmaceutical composition as described above for treatment of depression.

Colla corii asini oral solution with beatifying and chloasma removing effects and preparation method thereof

Erysipelas bacteriostatic ointment and preparation method thereof

Dissolved medicine for treating child diarrhea and preparation method thereof

Traditional Chinese medicine composition for promoting postpartum rehabilitation and preparation method and traditional Chinese medicine preparation thereof

A Chinese medicinal preparation for treating pancreatic cancer and a preparation method thereof

Prunella vulgaris mulberry leaf chrysanthemum pharmaceutical preparation, preparation method and application thereof

Aster tataricus formula granule and preparation method thereof

Blood pressure lowering plant active peptide and preparation method thereof

Health medicinal liquor with health function and preparation method thereof

Method for preparing acute communicable disease clearing and detoxification oral liquid

Traditional Chinese medicine composition for treating constipation as well as preparation method and application of traditional Chinese medicine composition

Preparation method of polyphenol extract in humulus lupulus

A Chinese herbal medicine composition for treating lung cancer and a preparation method thereof

Preparation process of medicinal preparation for treating bronchitis

Extraction technology of fructus lycii flavone

Mild gynecologic bacteriostatic liquid, and peparation method thereof

Traditional Chinese medicine composition for external use of low back pains

Medicine for treating hyperosteogeny and its preparation method

Chinese medicinal preparation for treating paraplegia and its preparation method

Herbal liquid and its preparation method

Traditional Chinese medicine composition for preventing and treating aged cognitive functional disorder and preparation method thereof

Traditional Chinese medicine composition for regulating liver and tonifying kidney as well as preparation method thereof

Fresh-extracted and freeze-dried white peony root granule decoction piece

Application of pithecellobium cypearia or extract to preparation of medicine for treating and/or adjunctively treating bronchopneumonia of livestock and poultry

Traditional Chinese medicine composition for treating deaf-mute or deafness

Immunity enhancement use of Apios americana Medikus tuber ethanol extract

COMPOSITIONS OF GRASOS POLIINSATURADOS ENRIQUECIDOS CON DHA

Se proporciona una composición lipídica de base vegetal que comprende niveles muy altos de DHA, junto con al menos otro ácido graso poliinsaturado de cadena larga (típicamente como ésteres de ácidos grasos). La composición contiene típicamente niveles bajos de EPA y ácido palmítico. La composición se puede obtener de una sola fuente mediante métodos de procesamiento convencionales y tiene propiedades de estabilidad mejoradas.

PHYTOCOMPLEX FROM BERGAMOT FRUIT, PROCESS OF MANUFACTURE AND USE AS DIETARY SUPPLEMENT AND IN THE PHARMACEUTICAL FIELD

The invention relates a phytocomplex obtained from the bergamot fruit albedo (Citrus Bergamia Risso & Poiteau), the production thereof and the use thereof, in particular under the form of dry extract, to be used as normalizer of the metabolic unbalances of lypemic and glycemic type, in the treatment of the cutaneous diseases with inflammatory or degenerative character, as painkilling/anti- inflammatory agent, as antineoplastic agent and dietary supplement.

COMPOSITION COMPRISING THE EXTRACT OF HERBS FOR PREVENTING OR TREATING NEURODEGENERATIVE DISORDERS

This invention relates to a pharmaceutical composition and a health functional food for preventing or improving neurodegenerative disorders comprising mixed herb extracts of Dioscorea Rhizoma and Dioscorea nipponica in a weight ratio of 3.5:1 (w/w). The herb extracts mixed Dioscorea Rhizoma and Dioscorea nipponica in a weight ratio of 3.5:1 have the synergetic effects on increasing the amount of nerve growth factor in vivo, increasing the neural cell proliferation, promoting the formation of neuritis and enhancing cognitive abilities. Thus, the herb extracts of the present invention may be used for a pharmaceutical composition and a health functional food for preventing or treating neurodegenerative disorders.

METHODS OF TREATING TUBEROUS SCLEROSIS COMPLEX WITH CANNABIDIOL AND EVEROLIMUS

The present disclosure provides methods of treating tuberous sclerosis complex comprising administering cannabidiol and everolimus.

Method of preparing akebia quinata extract and functional food using the same

Provided are a method of extracting saponin which is the physiologically active component of Akebia quinata with high efficiency, by sequentially subjecting to a) adding Akebia quinata flesh to Akebia quinata seeds and performing aging; and b) extracting with alcohol, a method of further improving saponin extraction efficiency by adding ginger, and a food composition containing the extract produced by this method. Higher added value may be created by improving the saponin extraction efficiency from Akebia quinata seeds using Akebia quinata flesh which has not been utilized when extracting saponin.

PHYTOCHEMICAL ENHANCED WATER

A method and formulation for fluids, such as drinking water, containing plant phytochemicals are disclosed. Some plants can survive in water without a root system, and the formulation includes fluid, such as water, with one or more of the plants maintained in the fluid. Cold storage resulted in enhanced production and excretion of phytochemicals from the plants into the fluid, including bacosides and bacopasides. These phytochemicals have been shown to exhibit antioxidant properties, promote memory and provide additional health benefits, as well as replace bottled water or other fluids as a means to ensure proper hydration. The fluids are useful for enhancing alertness.

Medicinal Composition of Amaranth Extract Origin Having Enriched Nitrate Content and a Method of Preparing the same

An extract of Amaranth, having enriched nitrate content, L-arginine, Flavonoids, saponins, alkaloids, carbohydrates, proteins, potassium, and with negligible amount of oxalic acid or oxalate content. The extract of Amaranth can be prepared from fresh or dried leaves and stem of Amaranth. Dosage forms of extract include fast melt tablet, lozenge, candy, chewing gum, beverage, tablet, capsule, pill, and powder. The extract of Amaranth enhances nitric oxide concentration, enhances nitrate level concentration, and enhances nitrite level in blood as well as in saliva. Administering the extract can lower blood pressure, increase physical endurance, increase swimming endurance, increase running endurance, and improve sexual performance among human beings. 1. An extract of Amaranth , the extract comprisingabout 0.1% to about 20% nitrates;about 0.1% to about 10% of L-arginine;about 0.001% to about 10% of flavonoids;about 0.01% to about 15% of saponins;about 0.01% to about 10% of alkaloids;about 10% to about 30% of carbohydrates;about 5% to about 25% of proteins;about 5% to about 25% potassium; and,about 0.01% to about 50% of total oxalic acid, wherein the total oxalic acid comprises free oxalic acid and oxalates.2. The extract of Amaranth of further comprising Vitamin C.3Amaranthus caudatus, Amaranthus cruentus, Amaranthus tricolor, Amaranthus blitum, Amaranthus viridis, Amaranthus dubius. The extract of Amaranth of claim 1 , wherein the Amaranth is selected from the group consisting of and combinations thereof.4. The extract of Amaranth of comprisingabout 3% to about 20% nitrates;about 1% to about 10% of L-arginine;about 1% to about 10% of flavonoids;about 5% to about 15% of saponins;about 3% to about 10% of alkaloids;about 10% to about 30% of carbohydrates;about 5% to about 25% of proteins;about 1% to about 5% of potassium; and,about 0.1% total oxalic acid, wherein the total oxalic acid comprises free oxalic acid and oxalates.5. A dosage form comprising the extract of ...

METHODS FOR REMOVING CONTAMINANTS FROM PLANT-DERIVED PHARMACEUTICALS

Methods of removing contaminants such as pesticides, herbicides, and fungicides from plant-derived pharmaceuticals, such as cannabis-derived pharmaceuticals, are disclosed. Plant-derived pharmaceuticals, such as cannabis-derived pharmaceuticals, and methods of using the plant-derived pharmaceuticals are also disclosed. 1. A method of removing contaminants from a plant-derived pharmaceutical , said method comprising:reacting one or more contaminants within a plant-derived extract with an alkali metal hydroxide in a polar solvent to form one or more contaminant by-products in a reaction mixture; andseparating the one or more contaminant by-products from the plant-derived extract so as to obtain a contaminant-reduced plant-derived extract.2. The method of claim 1 , wherein the one or more contaminants comprise one or more pesticides claim 1 , one or more herbicides claim 1 , one or more fungicides claim 1 , or any combination thereof.3. The method of claim 1 , wherein the one or more contaminants comprise one or more hydrolyzable pesticides.4. The method of claim 1 , wherein the alkali metal hydroxide comprises lithium hydroxide claim 1 , sodium hydroxide claim 1 , potassium hydroxide claim 1 , calcium hydroxide claim 1 , or ionic liquids such as 1-ethyl-3-methylimidazolium hydroxide.5. The method of claim 1 , wherein the polar solvent comprises methanol claim 1 , ethanol claim 1 , n-propanol claim 1 , isopropanol claim 1 , butanol claim 1 , dimethyl sulfoxide claim 1 , dimethylformamide claim 1 , or any combination thereof.6. The method of claim 1 , further comprising:forming a polar solvent solution comprising the alkali metal hydroxide in the polar solvent, wherein the alkali metal hydroxide is present in the polar solvent at a concentration of from about 0.125 grams (g) to 0.5 g of alkali metal hydroxide per milliliter (ml) of polar solvent.7. The method of claim 1 , wherein said reacting step comprises:adding the plant-derived extract to the alkali metal hydroxide ...

FEIJOA FRUIT EXTRACT

The invention relates to a feijoa fruit extract. In particular the invention relates to therapeutic uses of a feijoa fruit extract, processes for preparing the extract, and compositions comprising the extract. The feijoa fruit extract of the invention can be used in the treatment and prevention of rheumatoid arthritis and Type-2 diabetes.

METHODS OF TREATING TUBEROUS SCLEROSIS COMPLEX WITH CANNABIDIOL AND EVEROLIMUS

The present disclosure provides methods of treating tuberous sclerosis complex comprising administering cannabidiol and everolimus.

ANTIVIRAL COMPOSITION BASED ON EXTRACTS OF DURVILLAEA ANTARCTICA USEFUL FOR TREATING LESIONS CAUSED BY ALPHAHERPESVIRINAE VIRUS

Composition with antiviral activity comprising water-soluble extracts of Durvillaea antarctica substantially free of alginates and a carrier or vehicle, and the method of obtaining it. Where this composition serves to prepare an antiviral drug of topical application, to prevent or treat skin or oral lesions caused by herpes viruses of the subfamily Alphahehrpesvirinae, such as herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2) and varicella zoster virus (VZV), resistant or not to acyclovir (ACV).

Purified xanthophyll composition comprising (trans,R,R)-lutein and(trans,R,R)-zeaxanthin and process for the preparation thereof

The invention relates to a purified xanthophyll composition comprising (trans,R R)-lutein and (trans,R,R)-zeaxanthin, which is comprised of more than 80% of total xanthophylls and a process for the preparation thereof. Purified xanthophyll composition is comprised of selective isomers such as at least 85% by weight of (trans,R,R)-lutein and at least 15% by weight of (trans,R,R)-zeaxanthin. The composition is prepared by process of extraction from two different plant sources using industrially viable process and purified by employing food grade polar and non-polar solvents. The invention relates to purified xanthophyll composition which is selectively free from (R,S)-zeaxanthin and is suitable for human consumption.

STRENGTHENING AND TUMOR ELIMINATING TRADITIONAL CHINESE MEDICINE COMPOSITION, ITS PREPARATION METHOD AND APPLICATION

This invention provides a strengthening and tumor eliminating traditional Chinese medicine composition, its preparation method and application, which specifically relate to the technical field of the treatment of intermediate and advanced stage and postoperative malignant tumor, wherein the strengthening and tumor eliminating traditional Chinese medicine composition comprises: 8-30 parts of Radix Codonopsis, 5-30 parts of Rhizoma Atractylodis Macrocephalae, 5-30 parts of Poria cocos, 5-30 parts of Pseudobulb of Appendiculate Cremastra, 5-30 parts of Scutellaria barbata, 5-30 parts of Sarcandra glabra, 3-30 parts of peach kernel, 2-30 parts of Ligustrum lucidum, 5-30 parts of Eclipta and 1-20 parts of licorice. This invention also provides a preparation method of the described strengthening and tumor eliminating traditional Chinese medicine composition.

METHODS FOR CONTINUOUS EXTRACTION AND PURIFICATION OF A UNIQUE FLAVAN-3-OL EXTRACT FROM IMMATURE WHOLE GRAPE CLUSTERS AND COMPOSITIONS THEREOF

The present disclosure provides a novel process for the continuous extraction, purification and production of a flavan-3-ol extract from early harvested whole grape clusters. The final product from this process is particularly rich in monomeric and oligomeric flavan-3-ols and with an unusually high conversion of the final product into flavan-3-ol subunits under acid catalysis conditions. The oligomers and polymers in the final product are frequently referred to as proanthocyanidins in the field of polyphenol chemistry. The disclosure provides a novel process for the production of the final product via a continuous extraction process and with a final product having a unique composition.

Transdermal psychoactive alkaloid composition and preparation thereof

A transdermal psychoactive alkaloid composition including a psychoactive alkaloid extract or synthetic psychoactive alkaloid. The alkaloids in the extract are predominantly dephosphorylated rather than phosphorylated. The transdermal psychoactive alkaloid composition also includes an alcohol carrier, a permeation enhancer, a thickener or gelling agent, and optional further excipients. A process for obtaining a transdermal psychoactive alkaloid composition includes dephosphorylating the alkaloid during extraction, purifying the extracted alkaloid, and standardizing it to a specific concentration by adding measured quantities of excipients.

IMPROVEMENTS TO EXTRACTION METHODS, EXTRACTION SYSTEMS, COMPOUNDS AND FORMULATIONS

СПОСОБ ПОЛУЧЕНИЯ ВЕЩЕСТВА, ОБЛАДАЮЩЕГО АНТИМИКРОБНОЙ, ПРОТИВОВИРУСНОЙ И ИММУНОСТИМУЛИРУЮЩЕЙ АКТИВНОСТЬЮ, В ЧАСТНОСТИ, В ОТНОШЕНИИ ДЕНДРИТНЫХ КЛЕТОК, ВЕЩЕСТВО, ПОЛУЧЕННОЕ ЭТИМ СПОСОБОМ, И ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ НА ЕГО ОСНОВЕ

Изобретения относятся к фармацевтической промышленности, в частности к способу получения вещества; к веществу, обладающему антимикробной, противовирусной и иммуностимулирующей активностью в отношении дендритных клеток, и к фармацевтической композиции, обладающей антимикробной, противовирусной и иммуностимулирующей активностью в отношении дендритных клеток. Способ получения вещества заключается в том, что проростки картофеля подвергают водной экстракции, затем водный экстракт отделяют от осадка, добавляют солевой агент с последующим концентрированием, раствор замораживают, размораживают, фильтруют, осадок удаляют, а из раствора кислым солевым агентом осаждают комплексный биополимер-сырец с последующей обработкой его раствором щелочи, затем щелочной раствор диализуют против дистиллированной воды на фильтре и из полученного раствора с помощью гель-проникающей хроматографии выделяют комплексный биополимер. Вещество, полученное вышеуказанным способом, представляет собой комплексный биополимер ...

ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ ДЛЯ ЛЕЧЕНИЯ И ПРЕДОТВРАЩЕНИЯ ДЕГЕНЕРАТИВНЫХ НЕВРОЛОГИЧЕСКИХ НАРУШЕНИЙ, КОТОРАЯ СОДЕРЖИТ, В КАЧЕСТВЕ АКТИВНОГО ИНГРЕДИЕНТА, СМЕШАННЫЙ ЭКСТРАКТ КОРЫ КОРНЯ ПИОНА ПОЛУКУСТАРНИКОВОГО, КОРНЯ ДУДНИКА ДАУРСКОГО И КОРНЯ ВОЛОДУШКИ ИЛИ ЕГО ФРАКЦИЮ

Изобретение относится к фармацевтической промышленности, а именно к композиции для лечения или предотвращения дегенеративных неврологических нарушений. Фармацевтическая композиция для лечения или предотвращения дегенеративных неврологических нарушений содержит экстракт смеси коры корня пиона полукустарникового (Moutan Radicis Cortex), корня дудника даурского (Angelicae Dahuricae Radix) и корня володушки (Bupleuri Radix) в качестве активного ингредиента в массовом соотношении 1:0,2-5:0,2-5 (масс.:масс.:масс.), где экстракт экстрагирован с использованием воды, C-Cнизшего спирта или их смеси в качестве растворителя. Способ лечения или предотвращения дегенеративных неврологических нарушений включает стадию введения фармацевтически эффективной дозы экстракта смеси коры корня пиона полукустарникового (Moutan Radicis Cortex), корня дудника даурского (Angelicae Dahuricae Radix) и корня володушки (Bupleuri Radix) в массовом соотношении 1:0,2-5:0,2-5 (масс.:масс.:масс.) субъекту. Вышеописанная композиция ...

БИОЛОГИЧЕСКИ АКТИВНАЯ КОМПОЗИЦИЯ ИЗ ТОМАТОВ, ИМЕЮЩАЯ УМЕНЬШЕННОЕ СОДЕРЖАНИЕ ЛИКОПИНА

Группа изобретений относится к фармацевтической и косметической промышленности и касается композиции, обладающей противовоспалительной активностью. Композиция, обладающая противовоспалительной активностью, содержащая ликопин, один или оба из фитоена и фитофлуена и фитостеролы томатов, при этом концентрация ликопина находится в диапазоне от 0,3% до 2% по весу, и при этом весовое соотношение ликопина и одного или обоих из фитоена и фитофлуена находится в диапазоне от 1:1 до 1:2,5, где указанную композицию получают из томатов, и где концентрация фитостеролов составляет, по меньшей мере, 2% по весу. Способ получения композиции, содержащей ликопин, один или оба из фитоена и фитофлуена и фитостеролы. Применение вышеописанной композиции, обладающей противовоспалительной активностью, для получения лекарственного средства. Применение вышеописанной композиции, обладающей противовоспалительной активностью, для получения косметического или космецевтического средства. Вышеописанная композиция, с пониженным ...

КОСМЕТИЧЕСКОЕ ПРИМЕНЕНИЕ ЭКСТРАКТА ДЖИМНЕМЫ СИЛЬВЕСТРА

СПОСОБ УДАЛЕНИЯ ПЕСТИЦИДОВ ИЗ ЭКСТРАКТОВ GINKGO BILOBA И ЭКСТРАКТЫ, ПОЛУЧАЕМЫЕ УПОМЯНУТЫМ СПОСОБОМ

... 1. Способ получения фракции, обогащенной терпенами гинкго, включающий подвергание экстрактов Ginkgo biloba следующим стадиям:а) экстрагирования растворителем, не смешивающимся с водой, выбранным из сложных эфиров, хлорированных углеводородов, смесей углеводородов и спиртов, кетонов и смесей кетонов и спиртов,b) кристаллизации терпенов гинкго в смесях воды и С1-С5 спирта.2. Способ по п. 1, в котором растворитель, не смешивающийся с водой, является С2-С8 сложным эфиром.3. Способ по п. 2, в котором растворитель выбран из этилацетата, трет-бутилацетата или смеси толуол-бутанол.4. Фракция, обогащенная терпенами гинкго, полученная способом по любому из пп. 1-3.

СПОСОБ ПОЛУЧЕНИЯ ПОРОШКОВЫХ КОМПОЗИЦИЙ

PHARMACEUTICAL COMPOSITION FOR TREATMENT OF DEPRESSION AND PREPARATION METHOD THEREOF

Disclosed is a pharmaceutical composition for the treatment of depression, wherein the pharmaceutical composition is comprised of the following herbs in weight parts: 2-10 parts Ramulus Cinnamomi, 2-10 parts Rhizoma Zingiberis, 2-10 parts Fructus Schisandrae Chinensis, 2-8 parts Semen Ziziphi Spinosae, 2-8 parts Radix Codonopsis, 1-3 parts Rhizoma Dioscoreae, 0.5-2.5 parts Flos Inulae, 1-3 parts Caulis Bambusae in Taenia, 1-3 parts Fructus Trichosanthis, 1.5-4 parts Caulis Polygoni Multiflori, 1.5-4 parts Radix Ophiopogonis, 2-8 parts Radix Rehmanniae, 1.5-4 parts Cortex Moutan Radicis, 0.5-2.5 parts Fructus Gardeniae, 0.5-2.5 parts Herba Lophatheri, and 0.2-1.5 parts Folium Sennae. Also disclosed is a method for preparing the pharmaceutical composition as described above for treatment of depression.

Pharmaceutical composition for treatment of meopausal syndrome and preparation method thereof

Medicinal Ambrosia plant extracts

Phytoceutical compositions from organic extracts of the ...

Antihypertensive agent

Provided is a blood pressure-lowering agent that is safe and has a relaxing effect. The active ingredient of the blood pressure-lowering agent is S-1-propenyl cysteine or a salt thereof.

Application of persimmon leaf extract in the preparation of medicines for the treatment of primary insomnia

The present invention relates to the application of persimmon leaf extract in the preparation of medicines for the treatment of primary insomnia, especially the difficulty falling asleep. Each dose of persimmon leaf extract can increase the number of mice that fall asleep under the threshold dose of pentobarbital sodium in a dose-dependent manner, shorten the sleep latency induced by the upper threshold dose of pentobarbital sodium in a dose-dependent manner and extend the duration of sleep induced by the upper threshold dose of pentobarbital sodium. The persimmon leaf extract has good compliance and safety in the treatment of primary insomnia with low effective dose.

Traditional Chinese medicine composition for treating tumours, preparation method therefor and use thereof

Disclosed are a traditional Chinese medicine composition for treating tumours and a preparation method therefor, wherein the composition is prepared from ...

Phytochemical extraction system and methods to extractphytochemicals from plants including plants of the familycannabaceae sensu stricto

A method and system of and for extraction or removal of phytochemicals from plants, including those of the plant family Cannabaceae sensu stricto. More specifically, a method and system for extracting essential oils from plants, such as cannabis, without the use of a solvent ...

PURPLE WHEAT HEALTH CARE PRODUCT AND PREPARATION METHOD THEREOF

Abstract The present invention belongs to the technical field of health care products, and discloses a purple wheat health care product and a preparation method thereof. The purple wheat health care product is composed of the following components in parts by mass: 30-40 parts of purple wheat, 15-20 parts of plant protein extract, 10-12 parts of mushroom cap powder, 6-10 parts of Radix puerariae, 7-9 parts of Hippophae rhamnoides, 4-7 parts of a complex vitamin, 5-8 parts of dietary fiber powder and 2-3 parts of a composite additive. In the health care product provided in the present invention, the effects of the purple wheat are applied to the health care product, and the health care product with effects of prolonging life, improving memory, promoting growth and development and regulating immunity is produced by technologies such as an advanced 'one-step pelletizing' process, combination of Chinese and western medicines and low temperature sterilization. The purple wheat used by the present ...

Active components for neonatal intestinal defence and application thereof

Abstract The invention belongs to the technical field of intestinal defence medicines, and particularly discloses active components for neonatal intestinal defence and application thereof. Specifically, the active components consist of Lactobacillus bulgaricus, Bifidobacterium and Streptococcus thermophilus, which can be applied to the preparation of defensive medicines for treating or preventing neonatal intestinal diseases. Further, the medicines comprise the following components: Lactobacillus bulgaricus, Bifidobacterium, Streptococcus thermophilus, pine pollen, oligosaccharide, vitamins, montmorillonite powder and traditional Chinese medicine extracts. In the invention, the intestinal defence active components can protect the neonatal intestinal barrier and promote the formation of intestinal defence . Moreover, through the synergistic action of the active components, pine pollen, oligosaccharide, vitamin, montmorillonite powder and traditional Chinese medicine extract, the medicine ...

Blood pressure-lowering agent

Provided is a blood pressure-lowering agent that is safe and has a relaxing effect. The active ingredient of the blood pressure-lowering agent is S-1-propenyl cysteine or a salt thereof.

Method for producing dry extracts

The invention relates to a method for producing dry extracts of plants and to pharmaceutical preparations containing the same, more particularly phytopharmaceuticals, which contain at least one ethanolic/aqueous extract of a plant (drug), the plants being selected from the group consisting of: ...

PIPER LAETISPICUM EXTRACT AND PREPARATION METHOD THEREFOR AND USE THEREOF

Disclosed are a Piper laetispicum extract and a preparation method therefor and a use thereof. The Piper laetispicum extract comprises any one of sesamin, (2E, 6E)-N-isobutyl-7-(3,4-methylenedioxyphenyl)heptadienamide, (2E, 4E)-N-isobutyl dodeca-2,4-dienamide, (2E, 4E)-N-isobutyl-15-phenyl-2, 4-dienamide, (2E, 4E, 14Z)-N-isobutyleicosane-2, 4, 14-trienamide, (2E, 4E)-N-isobutyl-13-phenyl-2, 4-dienamide or a combination of the above. The Piper laetispicum extract can prevent depression.

PEA PROTEIN COMPOSITION HAVING IMPROVED NUTRITIONAL QUALITY

La présente invention a pour objet une composition de protéines de pois dont la qualité nutritionnelle, en particulier son PDCAAS, est améliorée, son procédé de préparation ainsi que l'utilisation de cette composition dans une composition alimentaire ou pharmaceutique.

PROCESS FOR REMOVING PESTICIDES FROM GINKGO BILOBA EXTRACTS, AND EXTRACTS OBTAINABLE BY SAID PROCESS

Process for removing pesticides from Ginkgo biloba extracts, which involves submitting an extract obtained by conventional methods to the following steps: a. Liquid-liquid extraction of the extract to obtain a medium polarity fraction containing ginkgo terpenes and pesticides not removable with hexane, and a high polarity fraction containing ginkgo flavone glycosides; b. crystallisation from the medium polarity fraction obtained at step a) to give an intermediate with a ginkgolide content of not less than 50%; c. crystallisation from the residual solution obtained at step b) to give an intermediate with a bilobalide content of not less than 50%; d. mixing of the high polarity fraction obtained at step a) with the ginkgo terpene intermediate and the bilobalide intermediate obtained at steps b) and c).

EXTRACT OF TOBACCO LEAF AND ITS APPLICATION FOR TREATMENT OF TOBACCO DEPENDENCE

An extraction and separation method for a Radix Notoginseng medicine material

Herba taxilli tea granule composition and preparation method thereof

Kidney-tonifying and clearing mixture and preparation method thereof

Plant flavonoid extraction and purification method and application

Pre-treatment method and preparation method of compound radix isatidis granules

Dandelion and herba violae extracting solution and preparation method thereof

Preparation method for coriolus versicolor extract and uric acid reducing application thereof

Oral liquid for enhancing immunity and preparation method thereof

Extraction technology for effective components in haworthia

Method for extracting total polyphenol from corn husks

Rosemary diterpene extract and application thereof in treating type-I diabetic nephropathy

Composition for treating pharyngitis as well as preparation method and application of composition

Medicine for treating acne and preparation method thereof

Fresh-extracted and spray-dried white peony root powder decoction piece

DETOXIFYING COMPOSITION FOR ORAL ADMINISTRATION AND METHOD FOR PREPARING SAME

Callicarpa nudiflora smearing preparation and preparing method thereof

External medicine wine with effects of relieving pain of muscles and bones, inhibiting bacteria and relieving itching

Method for preparing similar wild ginseng product and similar wild ginseng product

Method for extracting notoginseng folium saponins

Ixeris sonchifolia hance preparation with anti-gout effect

Health food capable of helping to reduce blood fat and preparation method thereof

ENVIRONMENTALLY-FRIENDLY PREPARATION METHOD OF COMPOSITION CONTAINING ANTI-INFLAMMATORY ACTIVE INGREDIENTS AND USE OF COMPOSITION

An environmentally-friendly preparation method of a composition containing anti-inflammatory ingredients and use of the composition are provided. The method includes: S1. weighing a specified volume of water and adjusting the pH, adding roots, and subjecting a resulting mixture to extraction at a high temperature; S2. adjusting pH of an obtained solution in step S1, adding roots, and heating a resulting mixture to boiling for extraction; S3. adding roots to an obtained boiling solution from the extraction in step S2, and subjecting a resulting mixture to extraction, filtration, and pH adjustment; S4. adding activated carbon to an obtained filtrate in step S3, and subjecting a resulting mixture to incubation and filtration; S5. adding a clarifying agent to an obtained filtrate in step S4, and subjecting a resulting mixture to standing and filtration; and S6. subjecting an obtained filtrate in step S5 to membrane separation. 1. An environmentally-friendly preparation method of a composition containing anti-inflammatory active ingredients , comprising the following steps:{'i': 'Sophora flavescens', 'S1. weighing a predetermined volume of water and adjusting a pH of the predetermined volume of water, adding roots to obtain a first resulting mixture, and subjecting the first resulting mixture to a first extraction at a predetermined temperature to obtain an extracted solution;'}{'i': 'Glycyrrhiza inflata', 'S2. adjusting a pH of the extracted solution obtained in step S1, adding roots to obtain a second resulting mixture, and heating the second resulting mixture to boiling for a second extraction to obtain an extracted boiling solution;'}{'i': 'Scutellaria baicalensis', 'S3. adding roots to the extracted boiling solution obtained in step S2 to obtain a third resulting mixture, and subjecting the third resulting mixture to a third extraction, a first filtration, and a pH adjustment to obtain a first filtrate;'}S4. adding activated carbon to the first filtrate obtained in ...

PASSION FLOWER SEED EXTRACT, AND COSMETIC, PHARMACEUTICAL OR DERMATOLOGICAL COMPOSITIONS CONTAINING SAME

The invention relates to a polyphenolic extract of passion flower seeds, in particular or seeds, comprising at least 30 percent by weight polyphenols, expressed as gallic acid equivalent, relative to the weight of the dry extract. The invention also relates to a method for preparing an extract of said type, a composition containing same, and the cosmetic, dermatological or therapeutic use thereof. 112-. (canceled)13Passiflora incarnataPassiflora edulis. A polyphenolic extract of seeds of passion flower , in particular of or , comprising at least 30 wt % polyphenols , expressed as gallic acid equivalents , relative to the weight of the dry extract , and at least 10 wt % organic acids , relative to the weight of the dry extract.14. The extract of claim 13 , comprising at least 35 wt % polyphenols claim 13 , expressed as gallic acid equivalents claim 13 , relative to the weight of the dry extract.15. The extract of claim 13 , wherein at least 50 wt % of said polyphenols are catechin derivatives claim 13 , expressed as gallic acid equivalents claim 13 , relative to the weight of polyphenols in the dry extract.16. The extract of claim 13 , wherein said organic acids are acetic acid claim 13 , malic acid claim 13 , citric acid or mixtures thereof.17. The extract of claim 13 , characterized in that it is obtained by solid/liquid extraction of passion flower seeds in a solvent selected from water claim 13 , glycerols claim 13 , glycols claim 13 , and mixtures thereof.18. The extract of claim 13 , characterized in that it is obtained by solid/liquid extraction of passion flower seeds in a solvent selected from the binary mixtures water/glycerol claim 13 , water/glycol claim 13 , and mixtures thereof.19. A method for preparing a polyphenolic extract of passion flower seeds as defined in claim 13 , said method comprising at least one step of solid/liquid extraction in a solvent selected from water claim 13 , glycerols claim 13 , glycols claim 13 , and mixtures thereof.20. The ...

SEMI-AQUEOUS METHOD FOR EXTRACTING A SUBSTANCE

A semi-aqueous method for extracting a substance. The method involves combining a first liquid or solid substance containing an extract with a semi-aqueous solution containing a water-soluble or water-emulsifiable (WSWE) compound. Said WSWE compound selectively dissolves extract during a dense phase COexpansion and salting-out process, which is simultaneously co-extracted using said dense phase CO, and desolvated to produce a COsalted-out solvent mixture containing extract. Said COsalted-out solvent mixture is treated using various secondary processes. The present invention is useful for producing extracts for use as additives in pharmaceuticals, nutraceuticals, cosmetics, beverages, or foods, and for quantitative analysis. 1. A semi-aqueous extraction method for recovering an extract from a substance , the steps comprising:a. Placing the substance into a pressure vessel;b. Adding a semi-aqueous solution, comprising a mixture of water and water-soluble or water-emulsifiable compound, to the pressure vessel;{'sub': '2', 'c. Pressurizing said semi-aqueous solution and the substance using dense phase COto establish a tunable extraction system in the pressure vessel;'}{'sub': '2', 'd. Expanding and salting-out said tunable extraction system using said dense phase COto produce a first separated phase, which comprises the water-soluble or water-emulsifiable compound containing the extract; and'}{'sub': 2', '2, 'e. Simultaneously co-extracting said first separated phase into said dense phase COto produce a second separated phase, which comprises a COsalted-out solvent mixture containing the extract.'}2. The semi-aqueous extraction method of claim 1 , wherein said substance comprises natural product claim 1 , pomace claim 1 , animal tissue claim 1 , soil claim 1 , sludge claim 1 , slurry claim 1 , potable water claim 1 , alcoholic beverage claim 1 , fermentation broth claim 1 , industrial wastewater claim 1 , fermented food claim 1 , or water-based extractant.3. The semi- ...

COMPOSITION AND METHOD TO ALLEVIATE JOINT PAIN USING PHOSPHOLIPIDS AND ASTAXANTHIN

A dietary supplement composition and associated method of use has the composition formulated in a therapeutic amount to treat and alleviate symptoms of joint pain in a person having joint pain. The composition includes astaxanthin and microbial fermented, low molecular weight hyaluronic acid or sodium hyaluronate (hyaluronan). The composition also includes at least one of a phospholipid, glycolipid, and sphingolipid. It is formulated into an oral dosage form and the astaxanthin is 0.1 to 15 percent by weight of the at least one phospholipid, glycolipid, and sphingolipid. 1. A method to treat and alleviate symptoms of joint pain by administering to a person having joint pain a therapeutic amount of a dietary supplement composition , including astaxanthin , pro-inflammatory low molecular weight microbial fermented sodium hyaluronate fragments having a molecular weight of 0.5 to 300 kilodaltons (kDa) , and a marine or seed oil and including a lipid selected from the group consisting of a phospholipid , glycolipid , and sphingolipid , and formulated into an oral dosage form , wherein the astaxanthin is 0.1 to 15 percent by weight of the marine or seed oil and the lipid selected from the group consisting of the phospholipid , glycolipid and sphingolipid.2. The method according to claim 1 , wherein the astaxanthin comprises a natural or synthetic ester or synthetic diol derivative.3. The method according to claim 1 , further comprising adding a pharmaceutical or food grade diluent to the marine or seed oil and the lipid selected from the group consisting of the phospholipid claim 1 , glycolipid and sphingolipid.4. The method according to claim 1 , wherein the phospholipid is selected from the group consisting of Phosphatidylcholine claim 1 , Phosphatidylethanolamine claim 1 , Phosphatidylserine claim 1 , Phosphatidylinositol claim 1 , Phosphatidic acid claim 1 , Lyso-Phosphatidylcholine claim 1 , Lyso-Phosphatidylethanolamine claim 1 , and Lyso-Phosphatidylserine.5. The ...

Method for preparing water extract of ashwagandha leaves which has enhanced anti-cancer activity utilizing cyclodextrin, and pharmaceutical composition containing ashwagandha leaves

It is an object of the present invention to provide a method for preparing a water extract of ashwagandha, which comprises increasing the amounts of withanone and withaferin A contained as active ingredients in the water extract of ashwagandha leaves. In addition, it is another object of the present invention to more economically and simply provide a pharmaceutical composition comprising ashwagandha leaves. The present invention relates to a method for preparing a water extract of ashwagandha leaves, which comprises extracting ashwagandha leaves with water in the presence of cyclodextrin, and a method for enhancing the anticancer activity of the water extract of ashwagandha leaves. The present invention also relates to a pharmaceutical composition for treating or preventing cancer, comprising the water extract of ashwagandha leaves. The present invention further relates to a pharmaceutical composition comprising dry powders of ashwagandha leaves and cyclodextrin.

COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING PULMONARY HYPERTENSION

The present invention provides a method of treating and/or preventing pulmonary hypertension in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of a bioactive peptide preparation derived from at least one botanical source. 1Rosa damascena, Juglans nigra, Syzygium aromaticum, Inonotus obliquus, Camellia sinensis, Hypericum perforatum, Forsythia suspensa, Scutellaria laterifloraVerbena hastata.. A method of treating or preventing pulmonary hypertension in a subject , the method comprising administering to the subject in need thereof a therapeutically effective amount of a bioactive peptide preparation comprising an extract from at least one plant species selected from the group consisting of , and2. The method of claim 1 , wherein the preparation inhibits or scavenges reactive oxygen species in the subject.3. The method of claim 1 , wherein the preparation treats or alleviates one or more pulmonary hypertension symptoms selected from the group consisting of shortness of breath claim 1 , fatigue claim 1 , chest pressure claim 1 , chest pain claim 1 , abdominal pain claim 1 , racing pulse claim 1 , heart palpitations claim 1 , poor appetite claim 1 , nausea claim 1 , lightheadedness claim 1 , fainting claim 1 , dizziness claim 1 , swelling claim 1 , cyanosis claim 1 , abnormal blood pressure claim 1 , and chronic cough.4. The method of claim 1 , wherein the preparation comprises a plant species extract that is insoluble in at least one solvent selected from the group consisting of trichloroacetic acid claim 1 , acetone claim 1 , methanol claim 1 , an ammonium acetate solution claim 1 , and any combinations thereof.5. The method of claim 1 , wherein the preparation comprises a plant species extract that is soluble in at least one selected from the group consisting of phenol and sodium dodecyl sulfate (SDS).6. The method of claim 1 , wherein the preparation comprises a plant extract produced through a ...

Preparation Method of the Albumin Peptide Combination and the Action of Inhibiting the Proliferation of Cancer Cells Thereof

The present invention discloses a preparation method of an albumin peptide combination and the action of inhibiting the proliferation of cancer cells thereof, the preparation steps comprise: mixing albumin and water in proportion, heating, adjusting pH, adding alkaline protease to perform enzymatic hydrolysis, deactivating, filtrating; mixing coix seed and water in proportion, decocting to extract, filtrating, adding certain proportional of water to filter residue, continue decocting to extract, collecting filtrates, determining solid matter content respectively, mixing two solutions, concentrating, spray drying, and obtaining an albumin peptide combination having the action of inhibiting the proliferation of cancer cells. The present invention found that, as compared with using coix seed individually, the effect of inhibiting the proliferation of cancer cells of albumin peptide combination is stronger, and process is simpler.

COMPOSITION FOR RELIEVING STRESS AND ENHANCING IMMUNITY AND PREPARATION METHOD THEREOF

The invention belongs to the technical field of health food and particularly relates to a composition for relieving stress and enhancing immunity and a preparation method thereof. The composition for relieving stress and enhancing immunity is calculated in parts by weight, 100-300 parts of a radix curcuma extract, 100-250 parts of a sea cucumber extract, 100-250 parts of a chlorella extract, 50-150 parts of a cranberry extract, 100-300 parts of a ginseng extract, 80-150 parts of a coconut oil extract and 100-200 parts of a palm oil extract. The composition can significantly enhance the body's immunity, relieve mental stress and improve the level of human health. In addition, the composition of the present invention is suitable for long-term use and has a small adverse reaction. 1. A composition for relieving stress and enhancing immunity , characterized in , the composition for relieving stress and enhancing immunity is calculated in parts by weight , 100-300 parts of a turmeric extract , 100-250 parts of a sea cucumber extract , 100-250 parts of a chlorella extract , 50-150 parts of a cranberry extract , 100-300 parts of a ginseng extract , 80-150 parts of a coconut oil extract , and 100-200 parts of a palm oil extract.2. The composition for relieving stress and enhancing immunity according to claim 1 , characterized in claim 1 , the composition for relieving stress and enhancing immunity is calculated in parts by weight claim 1 , further comprising 50-100 parts of lecithin and 50-80 parts of 5-hydroxytryptophan.3. The composition for relieving stress and enhancing immunity according to claim 1 , characterized in claim 1 , the composition for relieving stress and enhancing immunity is calculated in parts by weight claim 1 , 150-250 parts of a turmeric extract claim 1 , 100-200 parts of a sea cucumber extract claim 1 , 150-200 parts of a chlorella extract claim 1 , 80-100 parts of a cranberry extract claim 1 , 150-250 parts of a ginseng extract claim 1 , 100-150 ...

Arginine-rich Peptide Mixture, their Application Thereof in Cervical Cancer Therapy, and a Process for Producing same

A process for producing an arginine-rich peptide mixture and the application thereof in cervical cancer therapy is provided. The process includes the following steps: A suspension of walnut meal and egg albumin is pretreated with ultrahigh pressure, and then digested by alkaline proteinase and papain in separated steps with the ultrasonic and microwave-assisted extraction. The peptides of interest are isolated from filtration supernatant obtained after the enzyme digestion by reversed phase high-performance liquid chromatography. By using the peptide mixture as a template, acrylic acid and methyl acrylic acid as functional monomers, triethylene glycol dimethacrylate as cross-linking agent, and isopropylthioxanthone in acetone as a photoinitiator, polymerization is induced by ultraviolet light to form a surface imprinted membrane for isolating and enriching the peptides of interest from the supernatant. The arginine content in the peptide mixture is more than 18%. The arginine-rich peptide mixture is able to strongly suppress the proliferation of human cervical cancer Hela cells. The approach is applicable to reduce the cost of production and speed up the commercialization of large-scale production. 1. A process for producing an arginine-rich peptide mixture , comprising the following steps:(a) collecting a supernatant comprising peptides of interest, wherein de-fatted and pulverized walnut meal, egg albumin and water are mixed and stirred, pretreated with ultrahigh pressure, and subsequently enzymatic digested with ultrasonic-microwave-assisted extraction, wherein enzymes are inactivated by raising temperature and the supernatant is collected through plate and frame pressure filtration; and(b) isolating the peptides of interest from the supernatant, wherein the supernatant is freeze-dried, and the peptides of interest in freeze-dried coarse powder are subsequently isolated by using reversed phase high-performance liquid chromatography (RP-HPLC), wherein Everest C18 ...

Compositions, Methods, and Medical Compositions for Treatment of and Maintaining the Health of the Liver

Compositions and methods for treatment of and maintaining the health of the liver are disclosed that include a mixture of plant extracts, wherein the plant extracts comprise at least one extract, at least one gel powder, and at least one extract. Compositions and methods for treatment of and maintaining the health of the liver are disclosed that include a mixture of plant extracts, wherein the plant extracts comprise at least one extract enriched for at least one polymer or biopolymer, at least one gel powder enriched for at least one chromone, and at least one extract enriched for at least one lignan and organic acid. 1ArtemisiaAloeSchizandra. A composition for treatment of and maintaining the health of the liver , comprising a mixture of plant extracts , wherein the plant extracts comprise at least one extract , at least one gel powder , and at least one extract.2ArtemisiaAloeSchizandra. A composition for treatment of and maintaining the health of the liver , comprising a mixture of plant extracts from an extract enriched for at least one polymer or biopolymer , an gel powder enriched for at least one chromone , and a extract enriched for at least one lignan and organic acid.3ArtemisiaSchizandra. The composition of claim 1 , wherein the extract and the extract are blended in a weight ratio from 4:1 to 1:4.4AloeArtemisiaSchizandra. The composition of claim 1 , wherein the gel powder are further blended with a mixture of and extracts in a weight percentage of about 5% to about 50%.5Artemisia, SchizandraAloe. The composition of claim 1 , wherein the mixture of and leaf gel powder is in a ratio of 8:4:3.6Artemisia. The composition of claim 2 , wherein the extract comprises 0.01% to 99.9% of biopolymers with molecular weight higher than 500.7ArtemisiaArtemisia absinthium, Artemisia abrotanumArtemisia afra, Artemisia annuaArtemisia arborescens, Artemisia asiatica, Artemisia campestris, Artemisia deserti, Artemisia iwayomogi, Artemisia ludoviciana, Artemisia vulgaris, ...

Composition Comprising Plants Extracts that Synergistically Treat or Inhibit Pathological Conditions and Method of Making

A composition including plant extracts that synergistically treat or inhibit pathological conditions and a method for developing the composition is provided. The composition includes bioactive chemical agents extracted from the plant species including, but not limited to, acetonide, catalpol, hispidulin, loliolide, neptin, rhamnose, and scutellarin, and bioactive chemical agents extracted from the plant species including, but not limited to, cadinol, diosmetin, eugenol, furfural, hesperidin, luteolin, and piperitone. The method includes the steps of washing and plant material, freezing the plant material, cutting the frozen plant material into pieces, heating the plant material in purified water to form a resultant solution containing and plant extracts, cooling the resultant solution, and filtering the and plant material out of the resultant solution to produce the composition. 1Plantago majorMentha spicata) A composition for inhibiting or treating pathological conditions , the composition comprising an effective amount of a plurality of plant extracts from a plant species and an effective amount of plurality of plant extracts from a plant species.2) A composition for inhibiting or treating pathological conditions , the composition comprising an effective amount of a plurality of plant extracts including acetonide , adenine , allantoin , apigenin , apigenin-7-glucoside , asperuloside , aucubin , baicalein , baicalin , benzoic acid , caffeic acid , catalpol , chlorogenic acid , cinnamic acid , D-glucose , D-xylose , ferulic acid , fumaric acid , geniposidic acid , gentisic acid , glucoraphanin , hispidulin , hydroxycinnamic acid , loliolide , luteolin , luteolin-7-O-beta-D-glucoside , neochlorogenic acid , nepetin , oleanolic acid , P-coumaric acid , P-hydroxybenzoic acid , phenolcarbonic acid , rhamnose , saccharose , salicylic acid , scutellarin , sitosterol , succinic acid , sulforaphane , syringic acid , syringin , tyrosol , ursolic acid , vanillic acid , acetic ...

HERBAL COMPOSITION FOR BODY TREATMENT

The present invention discloses an herbal composition comprising a therapeutic effective amount of Cascalote () and a therapeutic effective amount of Ruda (). In another implementation, the herbal composition can also comprise of an effective amount of at least one pharmaceutically acceptable excipient for application to the body, including skin and tissue. The disclosed invention also includes a method for making the herbal composition and a method of application of the herbal composition. 1. An herbal composition comprising:a therapeutic effective amount of Cascalote; anda therapeutic effective amount of Ruda.2. The herbal composition of claim 1 , further comprising:an effective amount of at least one pharmaceutically acceptable excipient.3. The herbal composition of claim 1 , wherein a range of therapeutic effective amount of Cascalote is made from 0.25-2 lbs. of Cascalote per one gallon of pharmaceutically acceptable excipient.4. The herbal composition of claim 1 , wherein a range of therapeutic effective amount of Ruda is made from 0.25-2 oz. of Ruda per one gallon of pharmaceutically acceptable excipient.5. The herbal composition of claim 2 , wherein the at least one pharmaceutically acceptable excipient is in a range of 90% to 98% w/w of the total composition of the herbal composition.6. The herbal composition of claim 2 , wherein the pharmaceutically acceptable excipient comprises at least one of astringent claim 2 , antioxidant claim 2 , vaginal conditioning agent claim 2 , vasodillating agent claim 2 , thickening agent claim 2 , preservative claim 2 , lubricating agent claim 2 , colorant claim 2 , and water.7. The herbal composition of claim 2 , wherein the pharmaceutically acceptable excipient may be an orally or topically acceptable carrier and/or an orally or topically acceptable diluent.8. The herbal composition of claim 1 , for the treatment of at least one of skin and tissue.9. The herbal composition of claim 1 , for the treatment of a ...

A NANOBIOCOMPOSITE FORMULATION FOR WOUND HEALING AND A PROCESS FOR THE PREPARATION THEREOF

The present invention involves the isolation of plant based CNCs from the leaves of . For the formation of NCs, a novel greener approach using LE as reducing agent for in situ impregnation of AgNPs as fillers into CNCs as matrix is reported. The silver nitrate solution in three different concentrations of 1 mM, 5 mM and 10 mM was used to form NCs where AgNPs have been incorporated into CNCs matrix. The CNCs and NCs were characterized using SEM, TEM, XRD, Zeta potential, FT-IR, and UV-Vis spectroscopy. NCs developed in the form of film and ointment showed strong antimicrobial activity against both gram negative and gram positive bacteria. NCs wound dressing is capable of regulating wound exudates and providing moisture to wound responsible for faster healing of acute wounds. The observations from histopathological and biochemical assays confirmed that NCs enhance healing because of lesser inflammation, rapid angiogenesis, early collagen formation and enhanced rate of reepithelization. 1Syzygium cumini. A nanobiocomposite formulation (NCs) in ointment form comprising silver nanoparticles (AgNPs) and cellulose nanocrystals (CNCs) wherein the ratio of AgNPs and CNCs is in the range of 0.067%-0.4% w/w AgNPs: 7-8% w/w CNCs , and wherein the cellulose is derived from leaves.2. A process for the preparation of the nanobiocomposite formulation in ointment form as claimed in claim 1 , the method comprising:{'i': 'Syzygium cumini', 'a) treating washed and dried leaves with bleaching agent at pH in the range of 3.0-4.0 for a time period ranging between 2-3 h at a temperature ranging between 70-100° C. to obtain a bleached fibrous material;'}b) filtering and washing the bleached fibrous material as obtained from (a) followed by treating with acidified bleaching agent solution at a temperature ranging between 22-30° C. for a time period ranging 16-18 h to obtain acidified fibrous material;c) washing the acidified fibrous material as obtained from (b) followed by keeping it into 2 ...

SYSTEMS AND METHODS FOR CANNABINOID AND TERPENE EXTRACTION AND PURIFICATION

A method for preparing a purified extract may comprise extracting a crude extract from solids, dewatering the crude extract, removing chlorophyll from the crude extract, and distilling the crude extract thereby creating a purified extract. The extracting step may include contacting crude solids with an organic ester, thereby creating the crude extract and waste solids. The dewatering step may include contacting the crude extract with a solid dewatering agent and filtering the crude extract from the solid dewatering agent. The removing chlorophyll step may include contacting the crude extract with a solid absorbent agent, and filtering the crude extract from the solid absorbent agent. 1Cannabis. A method of preparing a purified extract , the method comprising: {'i': 'Cannabis', 'contacting crude solids with an organic ester, thereby creating e crude extract and waste solids;'}, '(a) extracting a crude extract, wherein the extracting comprises (i) contacting the crude extract with a solid dewatering agent; and', '(ii) filtering the crude extract from the solid dewatering agent;, '(b) dewatering the crude extract,wherein the dewatering comprises (i) contacting the crude extract with a solid absorbent agent; and', '(ii) filtering the crude extract from the solid absorbent agent;, '(c) removing chlorophyll From the crude extract,wherein the removing comprises{'i': 'Cannabis', '(d) distilling the crude extract to remove a majority of the organic ester, thereby creating the purified extract.'}2. The method of claim 1 , wherein the extracting step (a) comprises:heating the organic ester.3. The method of claim 2 , wherein the extracting step (a) comprises:refluxing the organic ester.4. The method of claim 3 , wherein the extracting step is performed in a soxhlet apparatus.5. The method of claim 2 , wherein the organic ester is heated to a temperature of 20 to 80 degrees Celsius.6. The method of claim 1 , wherein the extracting a crude extract step comprises:cooling the ...

BURN OINTMENT FOR PROMOTING TISSUE REGENERATION AND SKIN GROWTH, AND PREPARATION METHOD THEREFOR

A burn ointment for promoting tissue regeneration and skin growth comprises the following raw materials (pts. wt): cephalosporin (5-15), gentamicin (5-15), Radix Ginseng (5-20), propolis (10-20), Radix Lithospermi (5-20), Radix Scutellariae (10-20), montmorillonite (10-20), Radix Et Rhizoma Rhei (6-20), human placenta tissue liquid (10-20), borneol (0.5-5), vitamin B6 (5-15), vitamin C (8-15), and ointment matrix (200). The ointment can be used for rapidly repairing local damaged tissue, accelerating wound healing and shortening the healing days of III-degree burn. 1. A burn ointment for promoting tissue regeneration and skin growth , characterized in thatit comprises the following components by weight: 5-15 parts of cephalosporin , 5-15 parts of gentamicin , 5-20 parts of radix ginseng , 10-20 parts of propolis , 5-20 parts of radix lithospermi , 10-20 parts of radix scutellariae , 10-20 parts of montmorillonite , 6-20 parts of radix et rhizoma rhei , 10-20 parts of human placenta tissue liquid , 0.5-5 parts of borneol , 5-15 parts of vitamin B6 , 8-15 parts of vitamin C , and 200 parts of ointment matrix.2. The burn ointment for promoting tissue regeneration and skin growth according to claim 1 , wherein the cephalosporin is cefoperazone sodium.3. The burn ointment for promoting tissue regeneration and skin growth according to claim 1 , wherein the ointment matrix is Vaseline or W/O type matrix.4. A method for preparing a burn ointment according to claim 1 , for promoting tissue regeneration and skin growth claim 1 , said method characterized in that it comprises the following steps:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, '(1) preparing radix ginseng, propolis, radix lithospermi, radix Scutellariae and radix et rhizoma rhei in weight parts recited in , infiltrating in 75% alcohol for 18-24 hours, drying at 30-40° C., crushing, and screening with a 120 mesh sieve;'}{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, '(2) preparing montmorillonite in weight ...

COMPOSITIONS COMPRISING CBD FOR TREATING MENTAL DISORDERS

The present invention discloses compositions comprising CBD and several herbal extract and use thereof in treatment of mental disorders such as Attention Deficit Hyperactivity disorder (ADHD) and Post Traumatic Stress Disorder (PTSD). 116-. (canceled)17Bacopa monnieriCentella AsiaticaWithania Somnifera. A composition comprising from about 5 to about 22% by weight of CBD oil , from about 15 to about 40% by weight of extract , from about 15 to about 40% by weight of extract , and from about 15 to about 40% by weight of extract.18. The composition according to claim 17 , comprising from about 8 to about 20% by weight of CBD oil.19. The composition according to claim 17 , wherein said CBD oil comprises from about 55 to about 75% by weight of CBD.20. The composition according to claim 17 , wherein the CBD oil is obtained from plant extract claim 17 , or is synthetically prepared.21Bacopa monnieri. The composition according to claim 17 , comprising from about 25 to about 35% by weight of extract.22Centella Asiatica. The composition according to claim 17 , comprising from about 25 to about 35% weight of extract.23Withania Somnifera. The composition according to claim 17 , comprising from about 25 to about 35% by weight of extract.24Bacopa monnieriCentella AsiaticaWithania Somnifera. The composition according to claim 17 , comprising from about 8 to about 22% by weight of CBD oil claim 17 , from about 25 to about 35% by weight of extract claim 17 , from about 25 to about 35% by weight of extract claim 17 , and about from about 25 to about 35% by weight of extract.25. The composition according to claim 17 , wherein the composition further comprises an orally acceptable carrier.26. The composition according to claim 17 , wherein the composition is a pharmaceutical composition comprising one or more pharmaceutically acceptable excipients.27. The composition according to claim 17 , formulated for a systemic administration.28. The composition of claim 27 , wherein the systemic ...

Slim and aqua concentrate having standardized and triple salt stabilized (-)-Hydroxycitric acid from Garcinia cambogia extract for making concentrate and slimming water and their derived product for weight management

The present invention discloses a slim and aqueous extract of comprising (−)-hydroxycitric acid as dietary product for weight management. The present invention also discloses a process of preparation of aqueous extract wherein the fruit rinds are subjected to cold circulation to retain the phytochemical components and the aqueous extract is adjusted to neutral pH and stabilized with triple mineral salt of calcium, magnesium and potassium and decolorized using activated carbon. The colorless, odorless aqueous extract obtained is subjected to qualitative and quantitative analysis to obtain pure concentrate, which is useful in food, beverage and pharmaceutical industries as dietary supplement. The concentrate equivalent to 1500 mg of (−)-hydroxycitric acid on dried basis is used for the consumption with the distilled water. The slim and aqueous extract concentrate of is useful in treatment of overweight, obesity and hypercholesterolemia. 1) A composition for weight management , wherein the composition comprises:{'i': Garcinia cambogia', 'Garcinia cambogia', 'Garcinia cambogia, 'sup': '−1', 'extract at a concentration of 725-760 mgmlof aquasol concentrate of , wherein aquasol concentrate of comprises triple salt complex of (−)-hydroxycitric acid; and'}triple salt comprising calcium, magnesium and potassium.2Garcinia cambogia.) The composition as claimed in claim 1 , wherein the aquasol concentrate is prepared using dried fruit rind of3Garcinia cambogia,) A process for preparation of aquasol concentrate of the process comprising the steps of:{'i': 'Garcinia cambogia', 'a. extracting fruit rind using cold circulation of water using cone shaped stainless steel extractor;'}b. filtering liquid extract using a sparkler filter to remove one or more insoluble components;c. adsorbing the liquid extract filtrate containing the (−)-hydroxycitric acid using ion exchange resin to remove one or more unwanted compounds;d. eluting the adsorbed (−)-hydroxycitric acid using potassium ...

DETOXIFYING COMPOSITION FOR ORAL ADMINISTRATION AND METHOD FOR PREPARING SAME

A detoxifying composition for oral administration includes dried inflorescence stems from the pepper plant, that are optionally ground and optionally sieved, and/or a liquid or dry extract of pepper plant inflorescence stems. The pepper plant inflorescence stems are advantageously chosen from inflorescence stems from the , or pepper plants. The food composition or supplement or fortified foodstuff or dietary product containing same is used in order to promote the elimination of waste from the organism, in particular by the liver. 1. A detoxifying composition for oral administration , wherein said detoxifying composition comprises dried , optionally ground and optionally screened pepper plant inflorescence stems and/or a liquid or dry extract of pepper plant inflorescence stems.2Piper nigrumPiper longum.. The composition as claimed in claim 1 , wherein the pepper plant inflorescence stems are chosen from the inflorescence stems of the pepper plant or3. The composition as claimed in either of claim 1 , wherein the extract is an extract of said inflorescence stems with a polar solvent.4. The composition as claimed in claim 1 , wherein said composition contains at least 1% by weight.5. The composition as claimed in claim 1 , wherein said composition is in a drinkable form claim 1 , such as in the form of an infusion claim 1 , a decoction claim 1 , a maceration claim 1 , a flavored drink or any other drinkable form.6. A food supplement or a fortified food or a dietetic product comprising the composition as claimed in claim 1 , in weight proportions of between 0.1% and 85%.7. The food supplement or fortified food or dietetic product as claimed in claim 6 , wherein said food supplement also comprises at least one active agent chosen from: vitamins claim 6 , such as vitamin B6 or C; carotenoids claim 6 , such as beta-carotene or lutein; mineral trace elements claim 6 , such as magnesium claim 6 , calcium or iron; or extracts of rosemary claim 6 , blessed milkthistle claim 6 ...

METHOD FOR TREATING OR SUPPRESSING DEGENERATIVE BRAIN DISEASES BY CHINESE HERBAL MEDICINE COMPOSITION

The present invention discloses a method for treating or suppressing degenerative brain diseases, comprising a step of administrating a Chinese herbal medicine composition to a subject in need, wherein the Chinese herbal medicine composition comprises: a first herbal formula comprising 2-40 parts by weight of and 0.6-28 parts by weight of ; and a second herbal formula comprising 0.6-28 parts by weight of , 2-40 parts by weight of , and 20-96 parts by weight of a mixture of , and 1. A method for treating or suppressing degenerative brain diseases , comprising a step of administrating a Chinese herbal medicine composition to a subject in need , wherein the Chinese herbal medicine composition comprises:{'i': Panax ginseng', 'Angelica sinensis, 'a first herbal formula comprising 2-40 parts by weight of and 0.6-28 parts by weight of ; and'}{'i': Angelica sinensis,', 'Astragalus membranaceus', 'Ligustri fructus, Eclipta prostrata', 'Rehmannia glutinosa., 'a second herbal formula comprising 0.6-28 parts by weight of 2-40 parts by weight of , and 20-96 parts by weight of a mixture of , and'}2Panax ginsengAngelica sinensisAngelica sinensis,Astragalus membranaceusLigustri fructus, Eclipta prostrataRehmannia glutinosa.. The method as claimed in claim 1 , wherein the Chinese herbal medicine composition comprises the first herbal formula comprising 20-40 parts by weight of and 0.8-20 parts by weight of and the second herbal formula comprising 1-24 parts by weight of 2-40 parts by weight of claim 1 , and 20-96 parts by weight of the mixture of claim 1 , and3Ligustri fructus, Eclipta prostrataRehmannia glutinosa. The method as claimed in claim 1 , wherein a weight ratio of claim 1 , and in the mixture is 0.8-1.2:0.8-1.2:0.8-1.2.4. The method as claimed in claim 1 , wherein the Chinese herbal medicine composition further comprises an excipient selected from a group consisting of starch claim 1 , corn starch claim 1 , lactose claim 1 , microcrystalline cellulose claim 1 , ...

Methods and compositions for treating coronavirus infections

The present application relates to a compositions and methods comprising or expressing a HEVAR or MOMO30 protein derived from Momordica balsamina. The HEVAR or MOMO30 protein and/or a nucleic acid encoding the same may be used in methods for treating or preventing viral infections, particularly those caused by coronaviruses, such as SARS-CoV-2.

MULTIFUNCTIONAL FORMULATION COMPRISED OF NATURAL INGREDIENTS AND METHOD OF PREPARATION/MANUFACTURING THEREOF

This invention relates to a pharmaceutical preparation for the treatment of compromised tissue such as skin wounds and ulcers in humans and animals and a method of preparation. This is a multifunctional natural matrix meant for the treatment of compromised tissues which also relates to the anti-cancer transdermal patch for melanoma therapy. Further, the invention comprises for the treatment of Alzheimer's, and multiple sclerosis also. The composition consists of water-solubilized nano-sized formulation of non-aqueous solvent extract of phytopharmaceuticals in herbal, animal or synthetic biocompatible gel or on matrix coated or both. The composition is used as a topical device for the treatment of compromised tissues in its preferred embodiment. 135-. (canceled)36. A flexible , biocompatible bandage dressing comprising:a biocompatible, porous matrix; and{'i': Emblica officinalis,', 'Camellia sinsensis, 'a dried, phytopharmaceutical formulation on the biocompatible, porous matrix, wherein said dried, phytopharmaceutical formulation has a thickness of between about 10 μm to 500 μm and comprises 0.5 to 20 percent of non-aqueous extract from the plant 1.0 to 20 percent of non-aqueous extract from the plant , and 0.1 to 12 percent of water soluble curcumin.'}37. The flexible claim 36 , biocompatible bandage dressing of claim 36 , wherein said dried claim 36 , phytopharmaceutical formulation comprises 0.2 to 12.0 percent of aloe vera gel.38. The flexible claim 37 , biocompatible bandage dressing of claim 37 , wherein said aloe vera gel comprises 0.5 to 9.0 percent tocopherol.39. The flexible claim 37 , biocompatible bandage dressing of claim 37 , wherein said aloe vera gel is derived from a 0.5 to 3.0 percent aloe vera solution and 1.0 to 10.0 percent nano-silver solution.40. The flexible claim 36 , biocompatible bandage dressing of claim 36 , comprising liposomes that encapsulate at least a portion of said phytopharmaceutical formulation claim 36 , said liposomes having a ...

METHOD FOR TREATMENT OF THE HUMAN BODY BY THERAPY BY ADMINISTERING A COMPOSITION COMPRISING A PLANT EXTRACT OF THE SPECIE HEDYCHIUM CORONARIUM

The invention relates to a method for treatment of the human body by therapy by administering a composition comprising a plant extract of the specie and more particularly for use in protecting and/or activating at least one of the cellular clean-up systems. 1Hedychium coronarium.. A method for protecting and/or activating at least one cellular clean-up system in a human subject in need thereof comprising administering an effective amount of a composition comprising a plant extract of the specie2. The method according to for the treatment of environmental damage of the skin of the subject.3. The method according to wherein the protecting and/or activating at least one cellular clean-up system is mitochondrial protection and/or activation claim 1 , lysosomal protection and/or activation claim 1 , inhibition of cellular IL-8 release claim 1 , cellular production of β-endorphins claim 1 , inhibition of irregular melanin release claim 1 , orprotection and/or activation of the cellular transmembrane system by claudin restoration.4Hedychium coronarium. The method according to in which said plant extract of the specie is derived from flowers claim 1 , seeds claim 1 , fruits claim 1 , leaves claim 1 , stem claim 1 , roots and/or rhizomes of the plant.5Hedychium coronarium. The method according to claim 4 , in which said plant extract of the specie is derived from roots and/or rhizomes of the plant.6Hedychium coronarium,. The method according to in which said plant extract of the specie is derived from flowers claim 2 , seeds claim 2 , fruits claim 2 , leaves claim 2 , stem claim 2 , roots and/or rhizomes of the plant.7Hedychium coronarium,. The method according to in which said plant extract of the specie is derived from flowers claim 3 , seeds claim 3 , fruits claim 3 , leaves claim 3 , stem claim 3 , roots and/or rhizomes of the plant.8. The method according to for activating the least one cellular clean-up system in the human subject in need thereof.9. The method ...

PROCESS FOR REMOVING PESTICIDES FROM GINKGO BILOBA EXTRACTS, AND EXTRACTS OBTAINABLE BY SAID PROCESS

Process for removing pesticides from extracts, which involves submitting an extract obtained by conventional methods to the following steps: 1Ginkgo biloba. Extracts obtainable according to a process for removing pesticides from extracts , obtained by conventional methods , said process comprising:{'i': Ginkgo biloba', 'ginkgo', 'ginkgo, 'a) subjecting said extracts to liquid-liquid extraction to obtain a first fraction containing terpenes and pesticides not removable with hexane, and a second fraction containing flavone glycosides;'}{'i': 'ginkgo', 'b) crystallizing the terpenes from the first fraction obtained at step a) to give a ginkgolide intermediate with a ginkgolide content of not less than 50% w/w and a residual solution;'}c) crystallizing the residual solution obtained in step b) to obtain a bilobalide intermediate with a bilobalide content of not less than 50% w/w;{'i': 'Ginkgo biloba', 'd) mixing the second fraction obtained in step a) with the ginkgolide intermediate and the bilobalide intermediate obtained at steps b) and c) thereby removing said pesticides from said extracts.'}2. The extracts as claimed in claim 1 , wherein the extraction of step a) is carried out with a water-immiscible solvent selected from esters claim 1 , chlorinated hydrocarbons claim 1 , mixtures of hydrocarbons and alcohols claim 1 , ketones and mixtures of ketones and alcohols.3. The extracts as claimed in wherein the solvent is an ester having 2 to 8 carbon atoms.4ginkgo. The extracts as claimed in wherein the crystallisation of terpenes is carried out in mixtures of water and C1-C3 alcohols.5. The extracts as claimed in wherein the crystallisation from the terpene-rich fraction of step c) is carried out in water or in a mixture of water and C1-C3 alcohols. This U.S. non-provisional application is a continuation of U.S. application Ser. No. 13/258,715 filed on Nov. 18, 2011, which is a national stage of PCT/EP2010/002046 filed on Mar. 31, 2010 which claims priority to and the ...

Multifunctional formulation comprised of natural ingredients and method of preparation/manufacturing thereof

This invention relates to a pharmaceutical preparation for the treatment of compromised tissue such as skin wounds and ulcers in humans and animals and a method of preparation. This is a multifunctional natural matrix meant for the treatment of compromised tissues which also relates to the anti-cancer transdermal patch for melanoma therapy. Further, the invention comprises for the treatment of Alzheimer's, and multiple sclerosis also. The composition consists of water-solubilized nano-sized formulation of non-aqueous solvent extract of phyto-pharmaceuticals in herbal, animal or synthetic biocompatible gel or on matrix coated or both. The composition is used as a topical device for the treatment of compromised tissues in its preferred embodiment. 1. A ready to use , flexible , multifunctional biocompatible formulation and bandage dressing and a method of manufacturing thereof , said formulation and dressing comprising:a matrix based structure, having a plurality of biopolymers or synthetic polymers in the form of a formulation, with all ingredients working together in synergy, said matrix contained with the water soluble nano-form of non-aqueous solvent-extracted, water-insoluble phyto-pharmaceuticals from different natural sources; anda gel that is from herbal, animal or synthetic sources;such that the ingredients of formulation have much enhanced bioavailability than their naturally known values thus making it highly effective for wound healing, drug-delivery, anti-cancer therapy, anti-Alzheimer's and anti-multiple sclerosis.2Emblica officinalis, Acacia catechu, Azadirachta indica, Curcuma longa, Camellia sinsensis, Mimosa pudica, Ocimum sanctum, Phyllanthus emblica, Ricinus communis, Terminalia arjuna, Withania somnifera, Bacopa monnieriAloe vera. A ready to use claim 1 , flexible claim 1 , multifunctional biocompatible bandage dressing as claimed in claim 1 , wherein said plurality of biopolymers are selected from but not limited to etc claim 1 , combined with a ...

METHOD FOR OBTAINING OLIVE OIL AND AT LEAST ONE EXTRACT CONCENTRATED IN POLYPHENOLS AND A FUNCTIONAL INGREDIENT

A method comprising the stages of: olive input, separation of the stone from the olive skin and pulp, with the removal of the whole stone; electric pulsing of the olive paste generated in the previous stage, process of dehydration of the pulsed olive paste up to a humidity of less than 30% in a continuous vacuum drying machine and subsequent separation of the oil by centrifugation of the olive oil, followed by dehydration of the degreased pulp up to a humidity of less than 10%; and lastly, application of supercritical fluids (CO2 with or without modifier) to the degreased and dehydrated pulp, under agitation, pressure, temperature and time conditions, obtaining olive extracts and olive flour. The generation of waste, consumption of water, use of highly toxic solvents and loss of the sensory quality of the oil is avoided, the yields improved and the necessary times reduced. 1. A method for obtaining olive oil and at least one polyphenol concentrated extract and a functional ingredient characterised in that it comprises the stages of:{'b': 2', '3, 'Separating () the stone and skin from the olive pulp, obtaining the whole stone () on the one hand and, on the other, an olive paste;'}{'b': '4', 'Electric pulsing () of the olive paste with an electric field voltage of 1-3 kV/cm, frequency of 114-255 Hz and 2-10 pulses of 50-90 microseconds;'}{'b': '5', 'Dehydrating () the pulsed olive paste up to a humidity of <30% in a continuous vacuum drying machine under the following conditions: vacuum (<80 mbar of absolute pressure), temperature (<41° C.) and time (20-100 kg of evaporated water/h) or other conditions that preserve the thermolabile compounds of interest;'}{'b': 6', '7, 'Separating () the oil from the olive paste by centrifugation in a decanter with the necessary adjustments to treat de-stoned dehydrated pulp and obtainment of virgin olive oil ();'}{'b': '8', 'Dehydrating () the degreased pulp, after separating the oil, up to a humidity of less than 10% applying ...

TRADITIONAL CHINESE MEDICINE COMPOSITION FOR TREATING PROSTATE CANCER, PREPARATION METHOD AND APPLICATION THEREOF

The present invention relates to a traditional Chinese medicine composition for treating prostate cancer and its preparation method and application. The composition is prepared from and as raw materials in a weight ratio of 2-3:1-2:1-2:0.5-1.5:0.5-1.5 and prepared by mixed extraction or object extraction. The present inventions simplifies the prescription of the composition, is conducive to quality control, and reduces production cost, while the product curative effect remains unaffected, thus has a good application prospect. 112-. (canceled)13Ganoderma lucidum, Scutellaria baicalensis, Rabdosia rubescens, Panax notoginsengGlycyrrhiza. A traditional Chinese medicine composition for treating prostate cancer , characterized by: the composition is prepared from and as raw materials in a weight ratio of 2-3:1-2:1-2:0.5-1.5:0.5-1.5.14Ganoderma lucidum, Scutellaria baicalensis, Rabdosia rubescens, Panax notoginsengGlycyrrhiza. The traditional Chinese medicine composition for treating prostate cancer according to claim 13 , characterized by: the composition is prepared from and as raw materials in a weight ratio of 2-3:1.5-2:1.5-2:1-1.5:1-1.5.15Ganoderma lucidum, Scutellaria baicalensis, Rabdosia rubescens, Panax notoginsengGlycyrrhiza. The traditional Chinese medicine composition for treating prostate cancer according to claim 14 , characterized by: the composition is prepared from and as raw materials in a weight ratio of 3:2:2:1:1.16Ganoderma lucidum, Scutellaria baicalensis, Rabdosia rubescens, Panax notoginsengGlycyrrhiza. The traditional Chinese medicine composition for treating prostate cancer according to claim 14 , characterized by: the composition is prepared from and as raw materials in a weight ratio of 2:1.5:2:1.5:1.17Ganoderma lucidum, Scutellaria baicalensis, Rabdosia rubescens, Panax notoginsengGlycyrrhiza.. The traditional Chinese medicine composition for treating prostate cancer according to claim 13 , characterized by: the traditional Chinese medicine ...

Aloe extract and methods for producing the same

Disclosed herein is a method for preparing an aloe extract. The method comprises steps of, mincing a mesophyll of an Aloe in water; heating the minced mixture to 60-80° C.; filtering the mixture to produce a first filtrate; drying the first filtrate; reconstituting the dried first filtrate in water; subjecting the first filtrate or the reconstituent to column chromatography and eluting the column with a first polar solvent; concentrating the eluent; purifying the concentrate with active carbons; filtering the purified concentrate to produce a second filtrate; concentrating the second filtrate; and adding a second polar solvent to the concentrated second filtrate thereby producing the aloe extract. The present disclosure also encompasses the aloe extract prepared by the present method. Said aloe extract has desired contents of O-acetyl groups or polysaccharides, and is useful for manufacturing food, pharmaceutical, or cosmetic products.

Composition for preventing, treating and improving of voiding dysfunction comprising extract from Piper longum L.

The present invention relates to a pharmaceutical composition for preventing or treating voiding dysfunction and a health functional food for preventing or improving of voiding dysfunction, comprising extract of Piper Longum L. as an active ingredient. The extract of Piper Longum L. according to the present invention is not only harmless, but also has outstanding effects of preventing, treating and improving voiding dysfunction by being involved in various mechanisms related to voiding dysfunction simultaneously so that it may increase a micturition interval, decrease a micturition pressure, increase a bladder capacity, inhibit detrusor contraction and induce relaxation of detrusor.

PLANT OR MICROORGANISM-DERIVED CAROTENOID-OXYGEN COPOLYMER COMPOSITIONS, METHODS OF IDENTIFYING, QUANTIFYING AND PRODUCING SAME AND USES THEREOF

The present invention relates to carotenoid-oxygen copolymers, compositions, methods of identifying and quantifying carotenoid-oxygen copolymers in food and related sources, and methods of producing compositions comprising same. In one aspect the method of identifying and quantifying carotenoid-oxygen copolymers comprises an analysis of a low molecular weight marker compound in said sources. In another aspect the present invention provides a method of preparing compositions comprising said carotenoid-oxygen copolymers and/or enhancing levels of said copolymers in food sources in a sufficient and practically useful concentration to have beneficial effects in animals and humans, including beneficial immunological and health effects. 1. A method of identifying a source of carotenoid-oxygen copolymer comprising:(a) selecting a food plant source or microorganism source containing carotenoids;(b) processing the source under oxidative polymerization conditions; and(c) quantifying the amount of carotenoid-oxygen copolymer by directly isolating or identifying same from said processed source and/or by isolating or identifying an indicator of same from said processed source, to determine whether it is a source of carotenoid-oxygen copolymer.2. The method of claim 1 , wherein the sources have a starting amount of carotenoid claim 1 , which may provide upon oxidation the same amount of carotenoid-oxygen copolymer of 1-1000 μg/g wet weight or 10-10 claim 1 ,000 μg/g dry weight.3. The method of or claim 1 , wherein the oxidative polymerization conditions are selected from exposure to air or oxygen and one or more of drying claim 1 , powdering claim 1 , increasing exposure to heat claim 1 , light claim 1 , increasing the partial pressure of oxygen (ppO) or other factors that promote oxidation.4. The method of any one of - wherein the isolation of carotenoid-oxygen copolymer comprises at least one polar organic solvent extraction/non-polar solvent precipitation cycles.5. The method ...

Method for obtaining saponins from plants

The present application relates to a method for obtaining and purifying saponins from plant extracts, through a series of salting and filtrations steps, to provide high purity saponin extracts on large scale.

SYSTEMS AND METHODS OF CANNABIS OIL EXTRACTION

A oil extraction method includes performing grinding assisted extraction in the presence of solvent, co-solvent extraction with subcritical COcomprising, degassing the COand separating the mixture by centrifugation. 1cannabis. A oil extraction method , the method comprising: 'grinding plant material in the presence of solvent;', 'performing grinding assisted extraction comprising{'sub': '2', 'claim-text': {'sub': 2', '2, 'adding liquid COto the mixture, wherein the mixture is maintained at a temperature and pressure combination sufficient to maintain the liquid COin a subcritical state;'}, 'performing co-solvent extraction using subcritical COcomprising{'sub': '2', 'degassing the CO; and'}separating the mixture by centrifugation.2. The method of claim 1 , wherein the plant material ground in the presence of the solvent is wet plant material.3. The method of claim 1 , wherein a ratio of solvent to plant material present during the grinding assisted extraction is greater than 1:1 on a weight basis.4. The method of claim 1 , wherein a ratio of solvent to plant material present during the grinding assisted extraction is greater than 2:1 on a weight basis.5. The method of claim 1 , wherein grinding the plant material in the presence of solvent comprises grinding the plant material to micron scale.6. The method of claim 5 , wherein the plant material is ground to less than 20 microns during grinding assisted extraction.7. The method of claim 1 , wherein the solvent is a food grade solvent.8. The method of claim 1 , wherein the solvent is a non-polar solvent.9. The method of claim 8 , wherein the non-polar solvent is selected from pentane claim 8 , hexane claim 8 , benzene claim 8 , toluene claim 8 , carbon tetrachloride claim 8 , benzene claim 8 , glycerol monooleate claim 8 , diethyl ether claim 8 , hexane claim 8 , methylene chloride claim 8 , carbon dioxide claim 8 , methane claim 8 , ethylene claim 8 , D-limonene claim 8 , olive oil claim 8 , soybean oil claim 8 , ...

METHOD FOR PREPARING IRIDOID-RICH NONI FRUIT EXTRACT OR FRACTION THEREOF, METHOD FOR PREPARING IMMUNE-ENHANCING ACTIVE MATERIAL-RICH NONI FRUIT EXTRACT OR FRACTION THEREOF AND USE OF NONI FRUIT EXTRACT OR FRACTION THEREOF

The present invention relates to a method of preparing a noni fruit extract containing a high iridoid content or a fraction thereof, a method of preparing a noni fruit extract containing a high content of an immune-enhancing active substance or a fraction thereof, and a use of a noni fruit extract or a fraction thereof, and more specifically, the present invention provides a method of preparing a noni fruit extract containing a high iridoid content or a fraction thereof, including preparing a noni fruit extract by using ethanol in a specific concentration range as an extraction solvent, a method of preparing a noni fruit extract containing a high content of an immune-enhancing active substance or a fraction thereof, a pharmaceutical composition for enhancing immunity including the extract or a fraction thereof, a health functional food composition including the same constitution, a method of enhancing immunity using the extract or a fraction thereof, and a use of the extract or a fraction thereof in preparation of medicine for preventing or treating a disease associated with immune enhancement or reduced immunity. 1. A method of preparing a noni fruit extract containing a high iridoid content or a fraction thereof , comprising:a) pulverizing noni fruit;b) injecting 10 (w/w) % to 60 (w/w) % ethanol of 5 to 15 times the weight of the pulverized product into the pulverized product; andc) preparing an extract by extracting at 60° C. to 100° C. for 1 hour to 8 hours.2. The method of claim 1 , wherein the ethanol in step b) is 20 (w/w) % to 60 (w/w) % ethanol.3. The method of claim 1 , wherein the extraction in step c) is stirring extraction.4. The method of claim 1 , further comprising d) filtering and concentrating the extract to prepare a concentrated solution.5. The method of claim 1 , wherein the iridoid is one or more selected from the group consisting of deacetylasperulosidic acid (DAA) claim 1 , asperulosidic acid (ASPA) and asperuloside (ASP).613.-. (canceled)14. ...

Eye-refreshing agent to eliminate and alleviate eye fatigue and discomfort

An eye-refreshing agent, the raw materials of which include mung bean germs, eucalyptus leaves, mint leaves, clove leaves, camphor leaves and borneol. The plant cells thereof are respectively subjected to crushing, low-temperature freezing and centrifugation and sound membrane separation to prepare a water-soluble preparation. The preparation can prevent and alleviate visual fatigue and accelerate metabolism of the eye skin cells, and also has the effect of alleviating and improving eye bags and eye pseudo-wrinkles caused by eye fatigue.

ANTI-APICOMPLEXAN COMPOSITIONS

The invention is directed to Anti-Apicomplexan compositions, methods for producing the same, and methods for their use. 1. An Anti-Apicomplexan composition , comprising a combination of at least four compounds selected from the group consisting of: Hydroxytyrosol , 3 ,4 Dihydroxyphenylacetic acid , Tyrosol , Caffeic acid , p-Coumaric acid , Ferulic acid , and Oleuropein.2. The composition of claim 1 , comprising:a. 3,4 Dihydroxyphenylacetic acid, Tyrosol, Caffeic acid, and Oleuropein;b. 3,4 Dihydroxyphenylacetic acid, Tyrosol, Caffeic acid, Oleuropein, and Ferulic acid;c. 3,4 Dihydroxyphenylacetic acid, Tyrosol, Caffeic acid, Oleuropein, Ferulic acid and Hydroxytyrosol;d. 3,4 Dihydroxyphenylacetic acid, Tyrosol, Caffeic acid, Oleuropein and Hydroxytyrosol;e. 3,4 Dihydroxyphenylacetic acid, Tyrosol, Caffeic acid, Oleuropein and p-Coumaric acid:f. 3,4 Dihydroxyphenylacetic acid, Tyrosol, Caffeic acid, Oleuropein, Ferulic acid and p-Coumaric acid;g. 3,4 Dihydroxyphenylacetic acid, Tyrosol, Caffeic acid, Oleuropein, Ferulic acid, Hydroxytyrosol and p-Coumaric acid; orh. 3,4 Dihydroxyphenylacetic acid, Tyrosol, Caffeic acid, Oleuropein Hydroxytyrosol and p-Coumaric acid.36.-. (canceled)7. The composition of claim 1 , further comprising Tyrosol derivatives claim 1 , Hydroxytyrosol derivatives claim 1 , or both Tyrosol derivatives and Hydroxytyrosol derivatives.89.-. (canceled)10. The composition of claim 1 , comprising 3 claim 1 ,4 Dihydroxyphenylacetic acid claim 1 , Tyrosol claim 1 , Caffeic acid claim 1 , and Oleuropein claim 1 , wherein the ratio between the compounds is about 4-40 3 claim 1 ,4 Dihydroxyphenylacetic acid to about 4-40 Tyrosol to about 4-40 Caffeic acid to about 8-80 Oleuropein.11. The composition of claim 10 , further comprising at least one of:a. Ferulic acid, at a ratio between about 2.5 to 25 Ferulic acid;b. Hydroxytyrosol, at a ratio between about 2-20 Hydroxytyrosol;c. p-Coumaric acid, at a ratio between about 1.5 to 15 p-Coumaric acid;d. Tyrosol ...

CROTON LECHLERI COMPOSITIONS AND THEIR USE IN THE TREATMENT OF CYSTIC FIBROSIS

The present disclosure provides for the treatment cystic fibrosis and/or a bacterial infection in a cystic fibrosis patient via the administration to the lungs via inhalation of a pharmaceutical composition comprising a therapeutically effective amount of an extract of the tree. Also provided are details of studies on the effectiveness of an extract of the tree on cystic fibrosis and/or a bacterial infection in a cystic fibrosis patient and causative pathogens. 1Croton lechleriCroton lechleriCroton lechleriCroton lechleri. A method of treating a cystic fibrosis and/or a bacterial infection in a cystic fibrosis patient in a subject in need thereof comprising administering to the lungs via inhalation a therapeutically effective amount of a pharmaceutical composition containing filtered latex of , wherein the contains at least about 110 PPM of Gallocatechin , at least about 780 PPM of Epigallocatechin , about at least about 1.6 PPM of Catechin at least about 2 PPM of Epicatechin , at least about 45 PPM Taspine , and at least about 0.1 PPM of Dimethylcedrusin , wherein the therapeutically effective amount of filtered latex of Müll.Arg is about 3 wt % to 90 wt % , and the has a polydispersity index of about 0.5 to 0.85 , wherein the composition is suitable for administration via inhalation.2Croton lechleriCroton lechleri. The method of claim 1 , wherein the is Müll.Arg.3Pseudomonas aeruginosaPseudomonas aeruginosaStaphylococcus aureusStaphylococcus aureus. The method of claim 1 , wherein the bacterial infection is selected from the group consisting of a infection claim 1 , aMDR resistant infection claim 1 , a infection claim 1 , a methicillin-resistant infection claim 1 , and combinations thereof.4Pseudomonas aeruginosa. The method of claim 3 , wherein the bacterial infection is a infection.5Pseudomonas aeruginosa. The method of claim 3 , wherein the bacterial infection is a MDR resistant infection.6Staphylococcus aureus. The method of claim 3 , wherein the bacterial ...

Traditional chinese medicine composition and use thereof

The present disclosure relates to the field of drugs and health foods. Disclosed is a traditional Chinese medicine composition comprising GANODERMA polysaccharide, MORINDAE OFFICINALIS RADIX polysaccharide, POLYGONATI RHIZOMA polysaccharide, ANGELICAE SINENSIS RADIX oil and MYRISTICAE SEMEN oil. Experiments show that the traditional Chinese medicine composition has a scientific formulation, synergistic functions, without toxic and side effects, and not only has nutritional value but also inhibits the growth of tumor. Comparing with individual components, the composition significantly increases the percentages of CD4 + and CD8 + cells in lymphocytes of the tumor stroma, enhances body immune function, restores normal immune surveillance function, decreases VEGF and TGF-β1 positive cells in tumor tissue, assists in treating tumor, increases antitumor effects of chemotherapy drugs, improves immune status of body, has the function of restoring normal immune surveillance, preventing and assisting in treating tumor.

TRADITIONAL CHINESE MEDICINE COMPOSITION AND USE THEREOF

The present disclosure relates to the field of drugs and health foods. Disclosed is a traditional Chinese medicine composition comprising GANODERMA polysaccharide, GRIFOLA FRONDOSA polysaccharide, ANGELICAE SINENSIS RADIX oil and CINNAMOMI CORTEX oil. Experiments show that the traditional Chinese medicine composition has a scientific formulation, synergistic functions, without toxic and side effects, and not only has nutritional value but also inhibits the growth of tumor. Comparing with individual components, the composition significantly increases the percentages of CD4 and CD8 cells in lymphocytes of the tumor stroma, increases body immune function, recovers normal immune surveillance function, decreases the expression rate of VEGF and TGF-β 1 positive cells in tumor tissue, assists in treating tumor, increases antitumor effects of chemotherapy drugs, improves immune status of body, has the function of restoring normal immune surveillance, preventing and assisting in treating tumor. 1. A traditional Chinese medicine composition , comprising GANODERMA polysaccharide , GRIFOLA FRONDOSA polysaccharide , ANGELICAE SINENSIS RADIX oil and CINNAMOMI CORTEX oil.2. The tradition Chinese medicine composition according to claim 1 , wherein the weight ratio of GANODERMA polysaccharide claim 1 , GRIFOLA FRONDOSA polysaccharide claim 1 , ANGELICAE SINENSIS RADIX oil and CINNAMOMI CORTEX oil is (1 to 5): (1 to 5): (1 to 5): (1 to 5).3. The tradition Chinese medicine composition according to claim 1 , wherein the weight ratio of GANODERMA polysaccharide claim 1 , GRIFOLA FRONDOSA polysaccharide claim 1 , ANGELICAE SINENSIS RADIX oil and CINNAMOMI CORTEX oil is (1 to 2): (1 to 2): (1 to 2): (1 to 2).4. The tradition Chinese medicine composition according to claim 1 , wherein the weight ratio of GANODERMA polysaccharide claim 1 , GRIFOLA FRONDOSA polysaccharide claim 1 , ANGELICAE SINENSIS RADIX oil and CINNAMOMI CORTEX oil is 1:1:1.5:1.5.5. The tradition Chinese medicine ...

TRADITIONAL CHINESE MEDICINE COMPOSITION AND USE THEREOF

The present disclosure relates to the field of drugs and health foods. Disclosed is a traditional Chinese medicine composition comprising polysaccharide, polysaccharide, oil and oil. Experiments show that the traditional Chinese medicine composition has a scientific formulation, synergistic functions, without toxic and side effects, and not only has nutritional value but also inhibits the growth of tumor. Comparing with individual components, the composition significantly increases the percentages of CD4 and CD8 cells in lymphocytes of the tumor stroma, increases body immune function, recovers normal immune surveillance function, decreases the expression rate of VEGF and TGF-β 1 positive cells in tumor tissue, assists in treating tumor, increases antitumor effects of chemotherapy drugs, improves immune status of body, has the function of restoring normal immune surveillance, preventing and assisting in treating tumor. 1LYCII FRUCTUSPOLYGONATI RHIZOMACARYOPHYLLI FLOSCINNAMOMI CORTEX. A traditional Chinese medicine composition , comprising polysaccharide , polysaccharide , oil and oil.2LYCII FRUCTUSPOLYGONATI RHIZOMACARYOPHYLLI FLOSCINNAMOMI CORTEX. The tradition Chinese medicine composition according to claim 1 , wherein the weight ratio of polysaccharide claim 1 , polysaccharide claim 1 , oil and oil is (1 to 5):(1 to 5):(1 to 5):(1 to 5).3LYCII FRUCTUSPOLYGONATI RHIZOMACARYOPHYLLI FLOSCINNAMOMI CORTEX. The tradition Chinese medicine composition according to claim 1 , wherein the weight ratio of polysaccharide claim 1 , polysaccharide claim 1 , oil and oil is (1 to 2):(1 to 2):(1 to 2):(1 to 2).4LYCII FRUCTUSPOLYGONATI RHIZOMACARYOPHYLLI FLOSCINNAMOMI CORTEX. The tradition Chinese medicine composition according to claim 1 , wherein the weight ratio of polysaccharide claim 1 , polysaccharide claim 1 , oil and oil is 1:1:1.5:1.5.5. The tradition Chinese medicine composition according to claim 1 , which is in the form of a health food or a medicine.6. The tradition ...

METHOD OF STABILIZING WEIGHT AFTER A WEIGHT-LOSS DIET USING PHYTOECDYSONES

Phytoecdysones to avoid weight gain in obese mammals previously having undergone a hypocaloric weight-loss diet. The phytoecdysones are added to a food composition. The phytoecdysones can be from plants, such as quinoa. 1. A method of preventing weight regain in mammals after a hypocaloric weight-loss diet using phytoecdysones.2. The method according to claim 1 , further comprising stabilizing a diameter of adipocytes after the hypocaloric weight-loss diet.3. The method according to claim 1 , further comprising stabilizing an insulin sensitivity previously improved by the hypocaloric weight-loss diet.4. The method according to claim 1 , further comprising the step of selecting the phytoecdysones from 20-hydroxyecdysone claim 1 , makisterone A claim 1 , 24-epimakisterone A claim 1 , 24(28)-dehydromakisterone A claim 1 , 20 claim 1 ,26-dihydroxyecdysone claim 1 , and combinations of two or more of these components.5. The method according to claim 1 , further comprising the step of providing the phytoecdysones in a form of a plant extract.6. The method according to claim 5 , wherein the plant extract comprises at least 1% phytoecdysones by weight.7. The method according to claim 5 , wherein the plant extract is from quinoa.8. The method according to claim 1 , further comprising the step of incorporating the phytoecdysones into a composition that can be orally administered.9. A method for preparing a quinoa extract without saponins claim 1 , enriched with one or more phytoecdysones claim 1 , said method comprising the following steps:separating flour from bran of quinoa seeds;water extraction of the bran of the quinoa seeds to provide an aqueous extract;solid/liquid separation and centrifugation of the aqueous extract;heating of supernatant to precipitate proteins; andpurification by chromatography of the supernatant to enrich it with phytoecdysones and to eliminate saponins from the quinoa extract.10. A method of preventing weight regain in mammals after a hypocaloric ...

MEDICINAL AMBROSIA MARITIMA EXTRACTS

Phytoceutical compositions from organic extracts of the or plants and uses thereof for treatment of cancers is described. 1Ambrosia maritima. A method of treating bladder cancer , prostate cancer , triple negative breast cancer , lung cancer or pancreatic cancer , comprising administering an effective amount of a composition comprising an organic extract of together with a pharmaceutically acceptable carrier to a patient with cancer.2. The method of claim 1 , wherein said effective amount is administered daily for at least 6 weeks.3. The method of claim 1 , wherein said organic extract comprises at least one sesquiterpene lactone.4. The method of claim 1 , wherein said organic extract comprises one or more of the following sesquiterpene lactone: parthenin claim 1 , ambrosin claim 1 , damsin claim 1 , and neoambrosin.5. The method of claim 1 , wherein said organic extract comprises parthenin claim 1 , ambrosin claim 1 , damsin claim 1 , and neoambrosin.6Ambrosia hispida. A method of treating bladder cancer claim 1 , prostate cancer claim 1 , triple negative breast cancer claim 1 , lung cancer or pancreatic cancer claim 1 , comprising administering an effective amount of a composition comprising sesquiterpene lactones extracted from together with a pharmaceutically acceptable carrier to a patient with cancer.7. The method of claim 5 , wherein said effective amount is administered daily for at least 6 weeks.8Ambrosia maritima. A method of reducing cancer metastasis comprising administering an effective amount of a composition comprising sesquiterpene lactones extracted from together with a pharmaceutically acceptable carrier to a patient with cancer.9Ambrosia maritima. A method for enhancing the inhibition of p65 claim 5 , STAT3 claim 5 , GPR30 claim 5 , EGFR family of receptors claim 5 , β-catenin pathway and Rho-GTpase family activity in a patient claim 5 , comprising administering an effective amount of a composition comprising sesquiterpene lactones extracted from ...

Memory improving composition, preparation method and use thereof

The present invention relates to the technical field of health food, and discloses a memory improving composition and the preparation method and use thereof. The composition is made from Arillus Longan, Poria, Semen Nelumbinis, enzymatic extract of Semen Juglandis, phosphatidylserine and taurine. In the present invention, the sovereign drug Arillus Longan is combined with ministerial drugs Poria and Semen Nelumbinis to synergistically achieve the effect of nourishing heart for tranquillization and tonifying kidney & invigorating spleen. They are further combined with enzymatic extract of Semen Juglandis improving brain metabolism and enhances memory, functional factor phosphatidylserine increasing fluidity and enhances plasticity of cell membrane, and taurine improving memory, to achieve the purpose of memory improvement together. All kinds of raw materials are medicine homologous and new resource food, which are safe, have no toxic and side effects, and thus can be consumed as health food over a long period of time.

HEPATOPROTECTIVE TRADITIONAL CHINESE MEDICINE COMPOSITION, PREPARATION METHOD AND USE THEREOF

Disclosed is a hepatoprotective traditional Chinese medicine composition and a preparation method and use thereof. The composition is prepared by and clam. The present invention utilizes and to nourish the liver blood, and to invigorate the liver qi circulation, and clam to detoxify the liver. It combines several medicines to nourish the liver, smooth the liver qi and achieves a liver nourishing and protective efficacy, and is applicable to the population suffering from liver injury caused by an unhealthy lifestyle. The composition is characterized in using and clam as main raw materials. It combines various components reasonably, uses them in conjunction, and achieves a health-care function via multiple means and at multiple levels. 1Fructus Ligustri Lucidi, Herba Ecliptae, Radix Paeoniae Alba, Rhizoma Curcumae Longae. A hepatoprotective traditional Chinese medicine composition , which is prepared by and clam.2Fructus Ligustri Lucidi, Herba EcliptaeRadix Paeoniae AlbaRhizoma Curcumae LongaeRhizoma Curcumae LongaeRhizoma Curcumae Longae. The traditional Chinese medicine composition according to claim 1 , which is prepared by extracting and with ethanol and then mixing with a extract and a clam extract claim 1 , wherein the extract is an alcohol extract of and the clam extract is a water extract of clam.3. The traditional Chinese medicine composition according to claim 2 , wherein the parts by weight of the respective components are:{'i': Fructus Ligustri Lucidi,', 'Herba Ecliptae,', 'Radix Paeoniae Alba,', 'Rhizoma Curcumae Longae, '4-30 parts of 2-15 parts of 2-15 parts of 2-20 parts of the extract, and 2-10 parts of the clam extract.'}4. The traditional Chinese medicine composition according to claim 3 , wherein the parts by weight of the respective components are:{'i': Fructus Ligustri Lucidi,', 'Herba Ecliptae,', 'Radix Paeoniae Alba,', 'Rhizoma Curcumae Longae, '10-25 parts of 5-15 parts of 3-12 parts of 6-18 parts of the extract, and 4-8 parts of the clam ...

HERIPENES WITH PAIN-RELIEVING EFFECT, ACTIVE SUBSTANCES OF Hericium erinaceus MYCELIUM AND THE PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE HERIPENES OR ACTIVE SUBSTANCES

The present invention is related to an active substance of having a pain-relieving effect, and a pharmaceutical composition including the active substance. The active substance is prepared using the following steps: (a) inoculating a mycelium of on an agar plate and incubating at 15-32° C. for 8-16 days; (b) inoculating the incubated mycelia from step (a) into a medium in a flask and incubating at 20-30° C. and pH 4.5-6.5 for 3-5 days; (c) inoculating the incubated mycelia from step (b) into a medium in a fermentation tank and incubating at 24-32° C. and pH 4.5-5.5 for 8-16 days to obtain a fermented medium of the mycelia; and (d) desiccating the fermented medium of the mycelia from step (c) to obtain the powder of the mycelia, which is further purified and isolated to obtain a novel compound of 1. A method for relieving a pain in a subject suffering from one of a neuropathic pain and a cancer pain , comprising:{'i': 'Hericium erinaceus', 'providing an effective amount of a pharmaceutical composition comprising an active substance of a , and'}administering the pharmaceutical composition to the subject.2Hericium erinaceus. The method according to claim 1 , wherein the active substance of the is obtained by a preparation method comprising:{'i': 'H. erinaceus', '(a) inoculating an mycelium on an agar plate to be incubated;'}(b) inoculating the incubated mycelium in step (a) into a first medium on a small scale to be incubated; and(c) inoculating the incubated mycelium in step (b) into a second medium on a large scale to be incubated to obtain a fermented medium containing the active substance.3. The method according to claim 2 , wherein the incubation in step (a) is performed at 15-32° C. for 8-16 days.4. The method according to claim 2 , wherein the incubation in step (b) is performed at 20-30° C. claim 2 , pH 4.5-6.5 claim 2 , and a shaking rate of 100-250 rounds per minutes (rpm) for 3-5 days.5. The method according to claim 2 , wherein in step (c) the second medium ...

Enriched Root Powder Products and Methods of Producing Thereof

The present disclosure relates to methods of enriching root powder products, for example beetroot powder. In particular, the methods relates to increasing the nitrate content and/or reducing the sugar content of the root powder product. The disclosure also relates to root powder products with increased with at least 3% nitrate. 1. A method of increasing nitrate content and reducing sugar content in dried beetroot product , the method comprising:mixing dried beetroot product with an extraction mixture comprising an alcohol and an acid, wherein the alcohol is a low molecular weight alcohol that is liquid at room temperature;steeping the mixture of the dried beetroot product and the extraction mixture to produce a steeped mixture;filtering the steeped mixture to produce a filtered product; anddrying the filtered product to produce a dried filtered product.2. The method of claim 1 , wherein the alcohol is selected from the group consisting of:ethanol, methanol, propanol, isopropanol, and isobutanol.3. The method of claim 1 , wherein the acid is selected from the group consisting of: acetic acid claim 1 , formic acid claim 1 , sulfuric acid claim 1 , hydrochloric acid claim 1 , nitric acid claim 1 , hydrobromic acid claim 1 , phosphoric acid claim 1 , and perchloric acid.4. The method of claim 1 , wherein the ratio of the alcohol to acid in the extraction mixture is 3:1.5. The method of claim 1 , wherein the extraction mixture is free of water.6. The method of claim 5 , wherein the extraction mixture consists of absolute ethanol and glacial acetic acid.7. The method of claim 1 , wherein the mixture of the dried beetroot product and the extraction mixture is steeped for 24 hours prior to the filtering step.8. The method of claim 1 , wherein steeping the mixture of the dried beetroot product and the extraction mixture further comprising stirring the mixture of the dried beetroot product and the extraction mixture.9. The method of claim 1 , further comprising providing ...

Inhibition of formation of amyloid b-protein fibrils using cactus mucilage extracts

Alzheimer' s disease (AD) is the common neurodegenerative disorder characterized by the formation of extraneuronal accumulation of amyloid fibrils and intracellular neurofibrillary tangles of Amyloid β-Protein (Aβ) into plaques. Cactus mucilage extracted from Opuntia ficus - indica was analyzed in disturbing the aggregation pathway of Amyloid β-Protein (Aβ) fibrils and α-synuclein. Mucilage is a pectin polysaccharide with a backbone of α-D-galacturonic acid and β-L-rhamnose and a branch of arabinose or xylose. Two different fractions of mucilage can be extracted: pectin gelling extract which forms gels in the presence of Ca2+ ions (GE) and non-gelling extract (NE). The effectiveness of mucilage in disturbing the formation of Aβ fibrils was evaluated. Aβ monomeric species have been incubated along with different concentration of the mucilage extract in vitro. The aggregation kinetics of the Aβ proteins were monitored by Fourier transform infrared (FTIR) spectroscopy. Transmission electron microscopy (TEM) was used to monitor the aggregation process and fibril morphology. Our results indicate that introducing mucilage induces changes in the secondary structures of the Aβ peptides and results in amyloid detribalized structures. Our experimental results support the effectiveness of cactus mucilage in interfering with protein accumulation pathway and targeting the Aβ plaques.

CANNABINOIDS INFUSED COFFEE BEANS AND RAW NUTS

The present disclosure is directed to whole spectrum cannabinoids infused coffee beans or raw nuts and methods of producing the cannabinoids infused coffee beans or raw nuts. The coffee beans or raw nuts are infused in an overall two-step process, in which cannabinoids from a species are first infused into coconut oil, which in turn is used to infuse coffee beans or raw nuts with cannabinoids to generate the cannabinoids infused coffee beans or raw nuts. 1cannabis. A method of infusing an orally ingestible consumable with whole spectrum cannabinoids , the method comprising:{'i': 'cannabis', '(A) providing plant material;'}{'i': 'cannabis', '(B) freezing the plant material;'}(C) providing an orally ingestible oil at a temperature of 150° F.-200° F.;{'i': cannabis', 'cannabis, '(D) adding at least a portion of the frozen plant material of (B) to the oil of (C) to form a first plant material and oil mixture;'}{'i': 'cannabis', '(E) heating the plant material and oil mixture of (D) to a temperature of 150° F.-200° F. for 5-7 hours;'}{'i': 'cannabis', '(F) freezing the plant material and oil mixture of (E) into a solid, frozen biomass;'}{'i': 'cannabis', '(G) heating the solid, frozen biomass of plant material and oil mixture of (F) at a temperature of 150° F.-200° F. for 2-4 hours;'}{'i': cannabis', 'cannabis, '(H) straining the plant material and oil mixture of (G) to separate the oil from the plant material to yield a whole spectrum cannabinoids infused orally ingestible oil;'}(I) heating the cannabinoids infused oil of (H) to a temperature of 250° F. to 300° F. for 3-6 hours;(J) adding an orally ingestible consumable to the cannabinoids infused oil of (I) to form a consumable and cannabinoids infused oil mixture;(K) heating the mixture of (J) to a temperature of 175° F.-189° F. for 5-6 hours;(L) freezing the mixture of (K) to form a solid, frozen biomass mixture of consumable and cannabinoids infused oil;(M) heating the solid, frozen biomass mixture of consumable and ...

CANNABINOIDS INFUSED CONSUMABLES

The present disclosure is directed to cannabinoids infused consumables, including cacao beans, dehydrated fruit, and raw popcorn kernels, along with methods of producing the cannabinoid infused cacao beans, dehydrated fruit, and raw popcorn kernels. The consumables are infused in an overall two-step process, in which cannabinoids from a species are first infused into coconut oil, which in turn is used to infuse cacao beans, dehydrated fruit and raw popcorn kernels with cannabinoids to generate the cannabinoids infused cacao beans, dehydrated fruit and raw popcorn kernels. 1cannabis. A method of infusing an orally ingestible consumable with whole spectrum cannabinoids , the method comprising:{'i': 'cannabis', '#text': '(A) providing plant material;'}{'i': 'cannabis', '#text': '(B) freezing the plant material;'}(C) providing an orally ingestible oil at a temperature of 150° F.-200° F.;{'i': ['cannabis', 'cannabis'], '#text': '(D) adding at least a portion of the frozen plant material of (B) to the oil of (C) to form a first plant material and oil mixture;'}{'i': 'cannabis', '#text': '(E) heating the plant material and oil mixture of (D) to a temperature of 150° F.-200° F. for 5-7 hours;'}{'i': 'cannabis', '#text': '(F) freezing the plant material and oil mixture of (E) into a solid, frozen biomass;'}{'i': 'cannabis', '#text': '(G) heating the solid, frozen biomass of plant material and oil mixture of (F) at a temperature of 150° F.-200° F. for 2-4 hours;'}{'i': ['cannabis', 'cannabis'], '#text': '(H) straining the plant material and oil mixture of (G) to separate the oil from the plant material to yield a whole spectrum cannabinoids infused orally ingestible oil;'}(I) heating the cannabinoids infused oil of (H) to a temperature of 250° F. to 300° F. for 3-6 hours;(J) adding an orally ingestible consumable to the cannabinoids infused oil of (I) to form a consumable and cannabinoids infused oil mixture;(K) heating the mixture of (J) to a temperature of 175° F.-195° F. ...

TRADITIONAL CHINESE MEDICINE COMPOSITION AND PREPARATION METHOD AND USE THEREOF

The present invention relates to the field of traditional Chinese medicine formulation, particularly to a composition and the preparation method and use thereof. The traditional Chinese medicine composition provided by the present invention is produced from raw materials comprising TARAXACI HERBA, GLYCYRRHIZAE RADIX ET RHIZOMA, PLATYCODONIS RADIX, CITRI RETICULATAE PERICARPIUNM and PHYLLANTHI FRUCTUS. The traditional Chinese medicine composition adopts fewer herb medicines. By reasonable combination, the various herbal medicines mutually reinforce in terms of the effects of clearing throat, anti-inflammation and reducing phlegm, exhibit obvious synergistic effect. Pharmacological tests and clinical trials indicate that the traditional Chinese medicine composition has significant throat clear, anti-inflammatory, expectorant effects (p<0.05), and has no obvious toxic and side effects. 1. A traditional Chinese medicine composition , produced from raw materials comprising TARAXACI HERBA , GLYCYRRHIZAE RADIX ET RHIZOMA , PLATYCODONIS RADIX , CITRI RETICULATAE PERICARPIUNM and PHYLLANTHI FRUCTUS.5. A method for producing the traditional Chinese medicine composition according to claim 1 , comprising:subjecting TARAXACI HERBA, GLYCYRRHIZAE RADIX ET RHIZOMA, PLATYCODONIS RADIX, CITRI RETICULATAE PERICARPIUNM and PHYLLANTHI FRUCTUS to mixing, water extraction, alcohol precipitation to obtain the traditional Chinese medicine composition.6. The method according to claim 5 , wherein after water extraction and before alcohol precipitation claim 5 , the method further comprises:pooling and filtering the water extract, and concentrating the filtrate to a concentrate with a solid content of 20-50% at 20° C.7. The method according to claim 5 , wherein the alcohol precipitation is performed by adding ethanol to an ethanol concentration of 50-80% claim 5 , standing for 24 h or more claim 5 , discarding the filtration residue claim 5 , concentrating the supernatant to an extractum with ...

GLECHOMA LONGITUBE EXTRACT, PREPARATION METHOD FOR SAME, AND USE THEREOF IN SUGAR REDUCTION, WEIGHT LOSS, AND LIPID REDUCTION

Disclosed is a (Nakai) Kupr. extract, specifically compounds I and II, a preparation method for same, and a use thereof in preparing a medicament for blood glucose decease, blood lipids decrease, weight loss, and kidney disease treatment or a method for treatment of said diseases, and a composition containing the extract. 3Glechoma longituba. The extract of (Nakai) Kupr. of any of - , wherein the content of Compound I is more than 0.6% , preferably more than 25% , and more preferably more than 39%; the content of Compound II is more than 0.6% , preferably more than 25% , and more preferably more than 32%.4Glechoma longituba. The extract of (Nakai) Kupr. of any of - , wherein the contents of caffeic acid and rosmarinic acid are less than 0.5% , preferably less than 0.1%.5Glechoma longituba. The extract of (Nakai) Kupr. of any of - , wherein the aqueous solution in step a) has a water content of more than 40% , preferably more than 80% , and most preferably , the aqueous solution is water.6Glechoma longituba. The extract of (Nakai) Kupr. of any of - , wherein the extraction in step a) is extraction by heating reflux or ultrasonic extraction , preferably , performed 2 to 5 times.7Glechoma longitubaGlechoma longitubaGlechoma longituba. The extract of (Nakai) Kupr. of any of - , wherein the aqueous extract liquid of (Nakai) Kupr. obtained in step a) can also be optionally extracted by an organic solvent , the organic phase is discarded , and the treated aqueous extract liquid of (Nakai) Kupr. is left for further operation , wherein the organic solvent is preferably ethyl acetate or dichloromethane.8Glechoma longitubaGlechoma longituba. The extract of (Nakai) Kupr. of any of - , wherein the aqueous extract liquid of (Nakai) Kupr. obtained in step a) can be further refrigerated , preferably at 4-6° C. , after optional concentration , preferably concentration under reduced pressure.9Glechoma longituba. The extract of (Nakai) Kupr. of any of - , wherein the alcoholic ...

Use of overground part of hedychium coronarium koenig in reducing blood glucose; extracts and compositions of overground part of hedychium coronarium koenig and their uses

The present invention is related to the use of an overground part of Hedychium coronarium Koenig in lowering blood glucose, increasing insulin levels and treating and/or preventing diabetes without overly reducing blood glucose in a subject; i.e., not reducing blood glucose in a fasting subject. The present invention also relates to an extract and composition of the overground part of Hedychium coronarium Koenig and its use in lowering blood glucose, increasing insulin levels and treating and/or preventing diabetes.

NOVEL COMPONENT FOR CONTROLLING BIOLOGICAL FUNCTION

An object of the present invention is to prepare a novel food-derived exosome composition and to provide a cancer inhibitor or an agent for preventing decrease in tissue elasticity or an agent for improving elasticity containing a novel active ingredient. As a result of intensive studies on the purification process, the inventors have found that an exosome can be extracted from yeast mash and moromi by a unique production method. The inventors have found that the exosome recovered from the yeast mash and the moromi has a cancer cell proliferation inhibition ability, an ability to promote increase in the amount of granzyme, and an ability to promote expression of collagen and elastin. Accordingly, the inventors provide a composition for treating or preventing cancer and an agent for preventing decrease in tissue elasticity or an agent for improving elasticity, containing exosomes derived from yeast mash and moromi of sake.

PROCESS FOR THE PREPARATION OF POWDER COMPOSITIONS

Disclosed is a process for the preparation of powder compositions including a lipophilic extract of spp., a lipophilic extract of and phospholipids. Also disclosed are powder compositions obtainable by the process and pharmaceutical, nutraceutical and cosmetic formulations including the compositions. Also described is a use of the powder compositions and formulations thereof in the prevention and/or treatment of inflammatory and painful states. 1. A manufacturing process for preparing a powder composition comprising the following steps:{'i': Echinacea', 'Zingiber officinale, 'a) dispersing a lipophilic extract of spp., or a botanical lipophilic extract containing alkylamides, and a lipophilic extract of in at least one polar organic solvent and mixing until a solution or a suspension is obtained;'}b) adding at least one phospholipid to the solution, or suspension, of the lipophilic extracts and mixing the mixture;c) removing the organic solvent to obtain the powder composition.2. A manufacturing process according to claim 1 , wherein the obtained powder composition is then calibrated.3EchinaceaEchinacea angustifoliapurpurea.. A manufacturing process according to claim 1 , wherein the lipophilic extract of spp. is obtained from or4ZanthoxylumAcmella. A manufacturing process according to claim 1 , wherein the other botanical lipophilic extracts containing alkylamides are lipophilic extracts of spp. or spp.5ZanthoxylumZanthoxylum bungeanum, Zanthoxylum piperitum, Zanthoxylum americanumAcmellaAcmella oleracea.. A manufacturing process according to claim 4 , wherein the lipophilic extracts of spp. are obtained from and the lipophilic extracts of spp. from6. A manufacturing process according to claim 1 , wherein the organic solvent is a polar protic solvent claim 1 , like a claim 1 , straight or branched claim 1 , C-Calkyl alcohol claim 1 , or a polar aprotic solvent claim 1 , like a claim 1 , straight or branched claim 1 , C-Calkyl ester or C-Cdialkyl ketone.7. A ...

Kapok Tree Flower Extract, And Cosmetic, Pharmaceutical Or Dermatological Compositions Containing Same

The invention relates to an extract of flowers, preferably calyxes, from kapok trees, in particular , to a process for preparing same and to the extract obtainable by said process. The invention also relates to a composition comprising such an extract, the composition being advantageously a cosmetic, pharmaceutical or dermatological composition. The invention also relates to such a composition or such an extract for use in preventing or treating disorders or diseases of the skin, the mucous membranes or keratinous appendages and for use in preventing or treating vascular disorders. The invention finally relates to a cosmetic care process for the skin, the keratinous appendages or the mucous membranes, with a view to improving the condition thereof or the appearance thereof, which process consists in administering such a composition or such an extract. 1. Polyphenol-rich extract of Kapok tree flower comprising at least 15% by weight of polyphenols , relative to the total weight of the dry extract , and at least 15% by weight of oligoproanthocyanidins (OPC) , expressed as catechin equivalent , relative to the total weight of the dry extract.2. The extract of claim 1 , comprising at least 20% by weight of polyphenols claim 1 , relative to the total weight of the dry extract.3. The extract of claim 1 , further comprising at least 6% by weight of organic acids claim 1 , relative to the total weight of the dry extract.4. The extract of claim 1 , further comprising at least 5% by weight of flavonoids claim 1 , expressed as rutin equivalent claim 1 , relative to the total weight of the dry extract.5. The extract of claim 1 , wherein it is obtained by solid/liquid extraction of the flowers of the Kapok tree claim 1 , in a solvent chosen from amongst water claim 1 , glycols and mixtures thereof.6. The extract of claim 1 , wherein it is obtained by solid/liquid extraction of the flowers of the Kapok tree in a solvent chosen from amongst binary mixtures of water/glycol.7. ...

MAQUI BERRY EXTRACTS FOR USE IN THE TREATMENT OR PREVENTION OF BONE DISORDERS

The present invention relates generally to maqui berry for use in the treatment or prevention of bone injuries, diseases or defects, the promotion of healing of bone injuries, and the promotion of bone formation. Particular embodiments as disclosed herein find application in, inter alia, the treatment of bone fractures and in bone formation and regeneration. In particular, the present invention relates to the use of maqui berry extract in the manufacture of a medicament or dietary supplement for use in treating or preventing of bone injury or diseases or defects selected from the group of congenital bone defects, bone or spinal deformation, osteosarcoma, bone dysplasia, osteomalacia (rickets), osteogenesis imperfecta (brittle bone disorder), Paget's disease of the bone, osteoarthritis. 17.-. (canceled)8. A medicament or dietary supplement for use in the treatment or prevention of a bone disease or defect selected from the group of congenital bone defects , bone or spinal deformation , osteosarcoma , bone dysplasia , osteomalacia (rickets) , osteogenesis imperfecta (brittle bone disorder) , Paget's disease , comprising maqui berry extract , wherein the maqui berry extract comprises a minimum of 25% (w/w) delphinidins and a minimum of 35% (w/w) anthocyanins , and wherein the extract is obtained by the following steps:a) providing a crude extract of a plant material,b) filtering said crude extract;c) contacting said crude extract with an adsorbent, wherein said adsorbent, wherein the adsorbent is a resin which adsorbs said anthocyanins;d) washing said adsorbent; ande) eluting said anthocyanins from said adsorbent to obtain a composition enriched for anthocyanins.9. The medicament or dietary supplement for use according to claim 8 , wherein the maqui berry extract is obtained by an aqueous/alcoholic extraction agent.10. The medicament or dietary supplement for use according to claim 8 , wherein the maqui berry extract is obtained by an aqueous/alcoholic extraction agent ...

Method of extracting caffeic acid and rosemarinic acid from rosemary

The present disclosure relates to a method for extracting caffeic acid and rosmarinic acid from L., and more particularly, to a method for extracting caffeic acid and rosmarinic acid from L., the method comprising the steps of: (S1) preparing an extraction apparatus including an extractor for passing a solution contained in a main body unit through a filtration membrane to obtain a filtered solution, and dropping the filtered solution to the lower outside through a dropping unit connected to a lower portion of the main body unit, and a receiver located in the lower part of the extractor to collect the filtered solution that is dropped from the dropping unit; (S2) putting dried L. into the main body unit, and adding a solvent to the main body unit to immerse the dried L. at room temperature; and (S3) dropping a solution in which the dried L. has been immersed from the dropping unit to the receiver. 1Rosmarinus officinalis. A method for extracting caffeic acid and rosmarinic acid from L. , the method comprising the steps of:(S1) preparing an extraction apparatus including an extractor for passing a solution contained in a main body unit through a filtration membrane to obtain a filtered solution, and dropping the filtered solution to the lower outside through a dropping unit connected to a lower portion of the main body unit, and a receiver located in the lower part of the extractor to collect the filtered solution that is dropped from the dropping unit;{'i': Rosmarinus officinalis', 'Rosmarinus officinalis, '(S2) putting dried L. into the main body unit, and adding a solvent to the main body unit to immerse the dried L. at room temperature; and'}{'i': 'Rosmarinus officinalis', '(S3) dropping a solution in which the dried L. has been immersed from the dropping unit to the receiver.'}2. The method of claim 1 , wherein the extraction apparatus in the step (S1) further includes a reservoir for replenishing a new solution in the main body unit by a decreased amount of the ...

Methods of Extraction of Nitrosylated or Nitrated Derivatives of Ascorbic Acid from Myriciaria Dubia and Methods of Synthesis Thereof

The present invention relates to methods and strategies for extracting nitrosylated and/or nitrated derivatives and analogs from fruit and for synthesizing the same. The ascorbic acid derivatives and analogs have the chemical structure of: 2. The compound of claim 1 , wherein the derivatizing step comprises:adding independently hydrogen peroxide and sodium nitrite peroxide to a stirred solution of the ascorbic acid in a sodium citrate buffer to produce a peroxynitrite/peroxynitrous acid.3. The compound of claim 2 , wherein the molar ratio of said hydrogen peroxide to sodium nitrite to ascorbic acid to sodium citrate is 1:0.8:2:8.4. The compound of claim 2 , wherein said sodium citrate buffer maintains the pH value of said solution at about 3.7.5. The compound of claim 2 , wherein said peroxynitrite/peroxynitrous acid is at steady state in the solution.6. The compound of claim 1 , further comprising reducing at least one nitro group to an amine.7. The compound of claim 1 , further comprising isolating and purifying the compound.8. The compound of claim 1 , wherein derivatizing said ascorbic acid occurs over a period of about 24 hours.9. The compound of claim 1 , wherein said compound is 3-nitrosos-ascorbic acid claim 1 , 3-nitro-ascorbic acid claim 1 , 4-nitroso-ascorbic acid claim 1 , 4-nitro-ascorbic acid claim 1 , 6-nitroso-ascorbic acid claim 1 , 6-nitro-ascorbic acid.10. A pharmaceutical formulation claim 1 , comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'the compound of and a pharmaceutically acceptable delivery vehicle.'}11. The composition of claim 10 , wherein said pharmaceutically acceptable delivery vehicle is a liposome claim 10 , microspheres claim 10 , nanoparticles claim 10 , hydrogel claim 10 , or a combination thereof.12. A method for synthesizing an ascorbic acid analog claim 10 , comprising the steps of:adding hydrogen peroxide to a stirred buffered solution of ascorbic acid;adding sodium nitrite peroxide to said stirred buffered ...

A composition for preventing, treating, and improving of voiding dysfunction comprising extract of Piper longum L.

The present invention relates to a pharmaceutical composition for preventing or treating voiding dysfunction and a health functional food for preventing or improving of voiding dysfunction, comprising extract of L. as an active ingredient. The extract of L. according to the present invention is not only harmless, but also has outstanding effects of preventing, treating and improving voiding dysfunction by being involved in various mechanisms related to voiding dysfunction simultaneously so that it may increase a micturition interval, decrease a micturition pressure, increase a bladder capacity, inhibit detrusor contraction and induce relaxation of detrusor. 1Piper longum. A pharmaceutical composition for preventing or treating voiding dysfunction , comprising of L. as an active ingredient.2Piper Longum. The pharmaceutical composition for preventing or treating voiding dysfunction according to claim 1 , wherein said extract of L. is extracted from one or more extraction solvents selected from the group consisting of water claim 1 , alcohol claim 1 , glycerin claim 1 , butylene glycol claim 1 , propylene glycol claim 1 , methyl acetate claim 1 , ethyl acetate claim 1 , acetone claim 1 , benzene claim 1 , hexane claim 1 , diethyl ether claim 1 , chloroform and dichloromethane.3. The pharmaceutical composition for preventing or treating voiding dysfunction according to claim 2 , wherein said alcohol is anhydrous or hydrous lower alcohol with 1 to 4 carbon atoms.4. The pharmaceutical composition for preventing or treating voiding dysfunction according to claim 3 , wherein said anhydrous or hydrous lower alcohol is 30 to 100% by volume of methanol or ethanol.5Piper Longum. The pharmaceutical composition for preventing or treating voiding dysfunction according to claim 1 , wherein said extract of L. increases a micturition interval.6Piper Longum. The pharmaceutical composition for preventing or treating voiding dysfunction according to claim 1 , wherein said extract of L. ...

MAHONIA BEALEI EXTRACT WITH ANTIBACTERIAL INFLAMMATION-DIMINISHING AND GRANULATION-PROMOTING FUNCTIONS AS WELL AS PREPARATION METHOD AND APPLICATION THEREOF

The present invention discloses an application of a extract alone serving as active ingredient in preparation of drugs for treating chronic inflammatory traumas. The chronic inflammatory traumas comprise traumas initiated by chronic mastitis, diabetic foot, burn, chronic ulcer or Crohn's disease. A preparation method of the extract comprises steps: taking stems and leaves of a plant as raw materials, extracting with water, ethanol or a water-containing alcohol, filtering, concentrating to a small volume, and performing freeze drying for later use. The present invention has beneficial effects as follows: a drug preparation process is simple and reasonable in operation; an application value of the extract in treatment of a chronic inflammatory wound is clarified; and medicinal and drug efficacy study is developed, effective protection is realized on a utilization basis, and effects of off-site conservation and sustainable development can be achieved. 1mahonia bealeimahonia bealei. An application of a extract in preparation of drugs; wherein the extract alone serves as an active ingredient in preparation of drugs for treating chronic inflammatory traumas.2mahonia bealei. The application of the extract in preparation of drugs according to claim 1 , wherein the chronic inflammatory traumas comprise traumas initiated by any one of chronic mastitis claim 1 , diabetic foot claim 1 , burn claim 1 , chronic ulcer and Crohn's disease.3mahonia bealeimahonia bealei. The application of the extract in preparation of drugs according to claim 1 , wherein the extract are prepared into tablets claim 1 , capsules claim 1 , injections claim 1 , external solutions claim 1 , lotions claim 1 , liniments claim 1 , enemas claim 1 , ointments claim 1 , pastes claim 1 , patches and sustained-release or controlled-release preparations with medically acceptable carriers or excipients.4mahonia bealei. A preparation method for preparing the extract according to claim 1 , comprising the following ...

EXTRACT FROM INDIGO NATURALIS AND A PROCESS FOR PREPARING THE SAME

The present invention relates to a process for preparing an extract from one or more botanical raw materials, such as Indigo Naturalis and the extract itself. The present invention also relates to a composition comprising the extract, as well as the use of composition in medical or cosmetic applications. 1. An extract product of Indigo Naturalis prepared by a process comprising:a) extracting the Indigo Naturalis with a solvent to obtain a mixture of extraction, wherein the solvent is selected from the group consisting of dimethylformamide, ethyl acetate, ethanol, dimethylsulfoxide, dichloromethane, tetrahydrofuran, dimethylacetamide, acetone, 2-butanone, acetonitrile, isopropyl acetate, 2-methyl tetrahydrofuran, methyl tert-butyl ether, methanol, chloroform, terpene, water and a combination thereof,b) filtering the mixture of extraction to obtain a filtrate,c) concentrating the filtrate to obtain a crude extract,d) mixing the crude extract and hexane or heptane in reflux to obtain a first washing mixture,e) cooling and filtering the first washing mixture at room temperature obtain a first extract product, and i. mixing the first extract product and a solvent selected from the group consisting of hexane, ethanol and an aqueous solution of ethanol in reflux to obtain a second washing mixture, and', 'ii. cooling and filtering the second washing mixture at room temperature to obtain the extract product of Indigo Naturalis., 'f) washing the first extract product with a washing method comprising2. The extract product of Indigo Naturalis of claim 1 , wherein in a) claim 1 , the solvent is selected from the group consisting of dimethylformamide claim 1 , ethyl acetate claim 1 , ethanol claim 1 , and a combination thereof claim 1 , or an aqueous solution thereof.3. The extract product of Indigo Naturalis of claim 2 , wherein in a) claim 2 , the solvent is ethyl acetate claim 2 , ethanol or an aqueous solution of ethanol claim 2 , and the mixture of extraction is obtained by ...

EXTRACTION OF POLYPHENOLIC COMPOUNDS FROM POMACE

Methods of extraction of one or more polyphenolic compounds from pomace are described. The invention also provides uses of the extracts in the fortification of fruit juice, vegetable juice and foods, and as an antioxidant, an anti-inflammatory and an antifungal. 1. A method for extracting one or more polyphenolic compounds from pomace the method comprising:a) providing a pomace;b) subjecting the pomace to ultrasonication;c) extracting the pomace to produce an extract comprising one or more polyphenolic compounds; andd) subjecting the extract to ultrasonication.2. A method according to claim 1 , further comprising subjecting the pomace to microwave radiation before step b).3. A method according to claim 1 , further comprising subjecting the pomace to microwave radiation before step c).4. A method according to claim 1 , wherein step c) is carried out in water.5. A method according to claim 1 , further comprising subjecting the pomace to heat.6. A method according to claim 1 , further comprising mixing the pomace with water to provide a pomace/water mixture.7. A method according to claim 1 , further comprising cooling the pomace.8. A method according to claim 1 , further comprising filtering the pomace.9. A method according to claim 8 , further comprising centrifuging the filtrate from the pomace.10. A method according to claim 2 , wherein the pomace is subject to microwave radiation for a period of time from about 1 minute to about 5 minutes at a power between about 300 W to 1500 W.11. A method according to claim 2 , wherein the pomace is subject to microwave radiation for a period of time of about 3 minutes at a power of about 800 W.12. A method according to claim 1 , wherein the pomace and/or extract is subject to ultrasonication for a period of time of about 1 minute to about 120 minutes at a temperature between about 40° C. to about 100° C.13. A method according to claim 1 , wherein the pomace is subject to ultrasonication for a period of time of about 6 minutes ...

CONTROLLED CANNABIS DECARBOXYLATION FOR AN INFUSED SOLUBLE FAT PRODUCT

A process for controlling a decarboxylation of acidic cannabinoids for an infused soluble fat product, such as a butter product, is disclosed. In one embodiment for producing a butter product, raw cannabis base material is dried, pulverized, heated, and cooled to produce a decarbed cannabis material. The decarbed cannabis material is mixed with unsalted butter in an about 22:1 to and about 26:1 ratio, by weight, at ambient temperature and pressure, to produce a heterogenous butter material. The heterogenous butter material is canned and subjected to in-container thermal processing, including agitation during the thermal processing. The resulting heterogenous butter material is separated before cooling produces the butter product. 1. A process for controlling a decarboxylation of acidic cannabinoids for a butter product , the process comprising:drying raw cannabis base material at ambient temperature and pressure to produce a dried raw cannabis material, the dried raw cannabis material having kief formed thereon;pulverizing the dried raw cannabis material into small pieces to produce a pulverized cannabis material;heating the pulverized cannabis material at a temperature of about 220° F. (104° C.) to about 225° F. (107° C.) degrees for about 40 minutes to about 55 minutes to produce a decarbed cannabis material;cooling the decarbed cannabis material to room temperature;mixing the decarbed cannabis material with unsalted butter in an about 22:1 to an about 26:1 ratio, by weight, at ambient temperature and pressure, to produce a heterogenous butter material;canning the heterogenous butter material;thermal processing of the canned heterogeneous butter material in-container by water bath canning at a sub-boiling temperature for about 3 hours to about 5 hours to produce a processed heterogenous butter material, the sub-boiling temperature being between about 204° F. (96° C.) to about 210° F. (99° C.)agitating, during the thermal processing, the processed heterogeneous ...

HYDROLYSATE OF WATER EXTRACT OF GRACILARIOPSIS CHIANGII, AND PREPARATION PROCESS AND USE THEREOF

Disclosed herein are a hydrolysate of water extract of and a preparation process thereof. Also disclosed herein is a composition including the aforesaid hydrolysate of water extract of . The composition can be used in enhancing the moisture-retaining capacity of the skin, improving wound healing and reducing oxidative stress. 1Gracilariopsis chiangii. A process for preparing a hydrolysate of water extract of , comprising:{'i': 'Gracilariopsis chiangii', 'subjecting a alga to an extraction treatment with water so as to obtain a water extract; and'}subjecting the water extract to a hydrolysis treatment with bromelain.2Gracilariopsis chiangii. The process of claim 1 , wherein the weight ratio of the alga to water ranges from 1:0.5 to 1:5.3. The process of claim 1 , wherein the weight ratio of the water extract to bromelain ranges from 1:50 to 1:500.4. The process of claim 1 , further comprising conducting a solid-liquid separation treatment after the hydrolysis treatment so as to remove a solid portion resulting from the hydrolysis treatment.5Gracilariopsis chiangii. A hydrolysate of water extract of claim 1 , which is prepared by a process comprising:{'i': 'Gracilariopsis chiangii', 'subjecting a alga to an extraction treatment with water so as to obtain a water extract; and'}subjecting the water extract to a hydrolysis treatment with bromelain.6Gracilariopsis chiangii. The hydrolysate of claim 5 , wherein the weight ratio of the alga to water ranges from 1:0.5 to 1:5.7. The hydrolysate of claim 5 , wherein the weight ratio of the water extract to bromelain ranges from 1:50 to 1:500.8. The hydrolysate of claim 5 , wherein the process further comprises conducting a solid-liquid separation treatment after the hydrolysis treatment so as to remove a solid portion resulting from the hydrolysis treatment.9. A composition comprising a hydrolysate according to .10. The composition of claim 9 , which is for enhancing the moisture-retaining capacity of the skin.11. The ...

HYDROLYSATE OF WATER EXTRACT OF SYZYGIUM SAMARANGENSE, AND PREPARATION PROCESS AND USE THEREOF

Disclosed herein are a hydrolysate of water extract of and a preparation process thereof. Also disclosed herein is a composition which comprises the hydrolysate of water extract of The composition is suitable for whitening skin, enhancing the moisture-retaining capacity of skin, improving wound healing, and reducing oxidative stress. 1Syzygium samarangense,. A process for preparing a hydrolysate of water extract of comprising:{'i': 'Syzygium samarangense', 'subjecting a fruit material of to an extraction treatment with water so as to obtain a water extract; and'}subjecting the water extract to a hydrolysis treatment with bromelain.2Syzygium samarangense. The process of claim 1 , wherein the weight ratio of the fruit material of to water ranges from 1:0.5 to 1:5.3. The process of claim 1 , wherein the weight ratio of the water extract to bromelain ranges from 1:50 to 1:300.4. The process of claim 1 , further comprising conducting a solid-liquid separation treatment after the hydrolysis treatment so as to remove a solid portion resulting from the hydrolysis treatment.5Syzygium samarangenseSyzygium samarangense.. The process of claim 1 , wherein the fruit material of comprises a pulp of6Syzygium samarangenseSyzygium samarangenseSyzygium samarangense.. The process of claim 5 , wherein the fruit material of further comprises a peel of and a seed of7Syzygium samarangense,. A hydrolysate of water extract of which is prepared by a process comprising:{'i': 'Syzygium samarangense', 'subjecting a fruit material of to an extraction treatment with water so as to obtain a water extract; and'}subjecting the water extract to a hydrolysis treatment with bromelain.8Syzygium samarangense. The hydrolysate as claimed in claim 7 , wherein the weight ratio of the fruit material of the to water ranges from 1:0.5 to 1:5.9. The hydrolysate as claimed in claim 7 , wherein the weight ratio of the water extract to bromelain ranges from 1:50 to 1:300.10. The hydrolysate as claimed in claim 7 , ...

Antiobesity Agent Containing Walnut Extract

To provide an antiobesity agent. An antiobesity agent containing an extract of walnut branches, shells, or leaves as an active ingredient. 18-. (canceled)9. A method for treating obesity comprising a step of administering an antiobesity agent which comprises an extract of walnut branches.10. The method according to claim 9 , wherein the extract of walnut branches is an alcohol extract of walnut branches.11. The method according to claim 9 , wherein the treating obesity is preventing an increase in neutral fat amount claim 9 , cholesterol amount claim 9 , fat amount claim 9 , or body weight.12. The method according to claim 9 , wherein the treating obesity is inhibiting a binding between synoviolin and PGC-1β.13. The method according to claim 9 , wherein the treating obesity is inhibiting ubiquitination of PGC-1β by synoviolin.14. A method of manufacturing an antiobesity agent claim 9 , the method comprising:a first heating reflux step in which 1 part by weight of walnut branches is admixed with 4 to 30 parts by weight of an alcohol with concentration of 20 to 60 wt % to obtain a first mixture; and the first mixture is subjected at least once to heating reflux to obtain a first reflux liquid;a first filtering step in which the first reflux liquid obtained from the first heating reflux step is filtered to obtain a first filtrate and a first residue;a second heating reflux step in which 1 part by weight of the residue obtained from the first filtering step is admixed with 2 to 20 parts by weight of an alcohol with concentration of 20 wt % to 60 wt % to obtain a second mixture; and the second mixture is subjected at least once to heating reflux to obtain a second reflux liquid;a second filtering step in which the second reflux liquid obtained from the second heating reflux step is filtered to obtain a second filtrate;a first concentrating step in which the first filtrate is admixed with the second filtrate and then concentrated to have sugar content of 5% to 40% to ...

METHOD OF REDUCING WEIGHT REGAIN IN MAMMALS

Method of reducing weight regain in mammals after a hypocaloric weight-loss diet. A quinoa extract without saponins are used. 1. A method of reducing weight regain in mammals after a hypocaloric weight-loss diet using phytoecdysones.2. The method according to claim 1 , further comprising stabilizing a diameter of adipocytes after the hypocaloric weight-loss diet.3. The method according to claim 1 , further comprising stabilizing an insulin sensitivity previously improved by the hypocaloric weight-loss diet.4. The method according to claim 1 , further comprising the step of selecting the phytoecdysones from 20-hydroxyecdysone claim 1 , makisterone A claim 1 , 24-epimakisterone A claim 1 , 24(28)-dehydromakisterone A claim 1 , 20 claim 1 ,26-dihydroxyecdysone claim 1 , and combinations of two or more of these components.5. The method according to claim 1 , further comprising the step of providing the phytoecdysones in a form of a plant extract.61. The method according to claim 5 , wherein the plant extract comprises at least % phytoecdysones by weight.7. The method according to claim 5 , wherein the plant extract is from quinoa.8. The method according to claim 1 , further comprising the step of incorporating the phytoecdysones into a composition that can be orally administered.9. A method of reducing weight gain according to using a quinoa extract without saponins claim 1 , enriched with one or more phytoecdysones claim 1 , the quinoa extract prepared as follows:separating flour from bran of quinoa seeds;water extraction of the bran of the quinoa seeds to provide an aqueous extract;solid/liquid separation and centrifugation of the aqueous extract;heating of supernatant to precipitate proteins; andpurification by chromatography of the supernatant to enrich it with phytoecdysones and to eliminate saponins from the quinoa extract. The invention relates to a method of reducing weigh regain in mammals, specifically, reducing weight gain in obese mammals having previously ...

EXTRACT OF VICIA FABA BEANS

The extract of beans is prepared by soaking beans in distilled water overnight and then boiling in a water bath to reduce the volume of aqueous extract, which is then homogenized and filtered. The filtrate is concentrated to a smaller volume, lyophilized, and powdered. The lyophilized powder is extracted with hexane to remove oils and lipids. The oil-free lyophilized powder is dissolved in ethanol solvent and extracted for eight hours under reflux, and filtered. The volume of ethanol is reduced by a rotary evaporator, and a first off-white precipitate (sample A-1) is collected, washed with ethanol, and dried at 80° C. Mass spectrometry shows a molecular weight of 200.16447 g mol, and an empirical formula of CHNOis assigned. Intraperitoneal injection of mice with 50 mg/kg of A-1 twenty minutes prior to injection with strychnine protected the mice from strychnine-induced convulsions to the same extent as phenobarbitone (phenobarbital). 18-. (canceled)1019-. (canceled) This application is a division of application Ser. No. 16/145,090, filed Sep. 27, 2018, now pending.The disclosure of the present patent application relates to anticonvulsant compounds of potential use in the treatment of epilepsy or avoidance of epileptic seizures, and particularly to an extract of beans, also known as broad beans, fava beans, or faba beans, and method of extracting the beans to obtain an anticonvulsant.The plant , also known as the broad bean, faba bean, fava bean, etc., is an ancient flowering plant long cultivated in and native to the Mediterranean region and southwestern Asia. It is a legume belonging to the Fabaceae bean family, having a broad, leathery pod and green fruit that mature to a blackish-brown color. can grow in cold and hot countries, withstanding harsh and cold climates, in soils with high salinity and a wide range of pH (4.5-8.3), as well as in clay soils.Broad bean plants are highly susceptible to early summer infestations that can cause discoloration of pods, ...

AQUEOUS EXTRACTION PROCESS OF PLANTS, METHOD THEREOF, AND PRODUCT BY PROCESS

The preparation of an aqueous extract resulting from an aqueous extraction process of and and the chemical composition comprising said extract or fraction thereof, and the use of said composition or fraction thereof for treating or preventing cancers and inflammation related diseases, hair loss, stimulating hair growth, increasing energy production, and boosting immunity. 1. An aqueous extraction system comprising:an extraction vessel configured to store a fibrous container and a volume of water;a heating element configured to heat said volume of water within said extraction vessel, thereby creating water vapor and heated water;{'i': Cinnamomum cassia, Arctium lappa, Vitex agnus castus, Lonicera japonica, Acanthopanax gracilistylis, Raphanus sativus, Astragalus membranaceus', 'Hordeum vulgare;, 'a dry mixture placed within said fibrous container, said dry mixture comprised of one or more elements selected from the group consisting of: and'}said heated water configured to draw volatiles and an extraction mixture from said dry mixture;a condenser connected to said extraction vessel, said condenser configured to remove water vapor and volatiles; andsaid extraction mixture configured to be used as a treatment.2. The system of claim 1 , further comprising:a purified water reservoir and a first pump, said first pump configured to draw said volume of water from said purified water reservoir into said extraction vessel; andat least one valve, at least one second pump, and at least one filter aligned in a series and configured to draw said extraction mixture from said extraction vessel into one or more storage containers.3. The system of claim 1 , further comprising:{'i': Cinnamomum cassia,', 'Arctium lappa,', 'Vitex agnus castus,', 'Lonicera japonica,', 'Acanthopanax gracilistylis,', 'Raphanus sativus,', 'Astragalus membranaceus', 'Hordeum vulgare, 'said dry mixture comprising 220 mg of 110 mg 220 mg 110 mg 110 mg 110 mg 110 mg and 220 mg for each liter of said volume of ...

COMPOSITION, PREPARATION METHOD THEREOF, AND APPLICATION THEREOF IN THE PREVENTION AND TREATMENT OF MAMMARY GLAND DISEASE

The present disclosure relates to the technical field of traditional Chinese medicine technology, especially to a composition, a preparation method thereof and an application in the prevention and treatment of mammary gland diseases. The present disclosure provides a composition consisting of Rehmanniae Radix Praeparata, Lycii Fructus, Polygonati Rhizoma, Radix Codonopsis Pilosulae, Paeoniae Radix Alba, Cyperi Rhizoma (processed with vinegar) and Grape Seed. The composition has functions of improving hyperplasia of mammary gland and/or anti-oxidation. Compared with each control group, the composition provided by the present disclosure has the optimal effects, and the effect has statistical differences, indicating that the components in the composition provided by the present disclosure are reasonably arranged and can play a good synergistic effect. Furthermore, the preparation is safe and has no side effects. 4. An extract made from the composition according to .5. A method for preparing the extract according to claim 4 , comprisingextracting Cyperi Rhizoma (processed with vinegar) and Paeoniae Radix Alba with water, concentrating to powder by spraying drying, to give component A;extracting a combination of Rehmanniae Radix Praeparata, Polygonati Rhizoma, Lycii Fructus and Radix Codonopsis Pilosulae by water extraction and alcohol deposit to obtain a precipitation, and drying the precipitation to powder, to give component B;extracting Grape Seed with an alcohol, column separating, gathering effluent fraction of ethanol, and drying the effluent fraction to powder, to give a Grape Seed Extract;and mixing component A, component B and the Grape Seed Extract to give the extract.6. The method according to claim 5 , wherein in the process of water extraction claim 5 , the weight of water is 5-20 times based on a total weight of the medicinal materials claim 5 , the extraction temperature is 80-100° C. claim 5 , the duration is 0.5-4 h claim 5 , and the extraction is ...

DIETARY SUPPLEMENT COMPRISING LUTEIN FOR TELOMERE PROTECTION, AND METHOD FOR PRODUCTION THEREOF

This invention discloses a dietary supplement composition. More particularly, the invention deals with the method of production of dietary supplement composition comprising natural lutein and tocopherols, optionally along with acceptable additives to a subject, wherein the dietary supplement composition reduces, ameliorates, prevents, or reverses the oxidative DNA damage and slows telomere shortening. Invention further describes a method for promoting detoxification in cells of a subject, including administering to the subject an oral formulation comprising a plurality of agents that stimulate natural stem cell production within the body; repair the stem cells fibroblasts; pro-long the replicative lifespan; slow the telomere shortening; improve the telomerase activation in stem cells; improve the telomerase activation in body cells; promote the health-span in humans; and reduce the oxidative stress. The present invention can be used for the development of functional food, dietary plan and as a nutritional supplement. 1) A method of reducing , ameliorating , preventing , or reversing oxidative DNA damage in a subject , comprising orally administering an effective dose of a dietary supplement composition comprising natural lutein and tocopherols , optionally along with acceptable additives to a subject , wherein the dietary supplement composition reduces , ameliorates , prevents , or reverses the oxidative DNA damage and slows telomere shortening.2) The method of claim 1 , wherein the dietary supplement composition comprising natural lutein is produced by a method comprising:a. saponifying Marigold Oleoresin in the presence of an alcohol or organic solvent and an alkali for about 2 hours at a preferable temperature of about 80 to 85 degrees centigrade;b. adding an aqueous solution to the reaction mass, hereby obtaining a neutralized mass;c. filtering the neutralized mass, to obtain the Lutein crystals;d. further crystalizing the Lutein crystals in the presence of ...

TRADITIONAL CHINESE MEDICINE COMPOUND COMPOSITION WITH ANTI-ANXIETY EFFECT AND PREPARATION METHOD AND APPLICATIONS THEREOF

A traditional Chinese medicine compound composition with anti-anxiety effect and its preparation method and application are disclosed. The traditional Chinese medicine compound composition with anti-anxiety effect is prepared by compounding the extract, the extract, the extract and the extract. The traditional Chinese medicine compound composition has no toxic side effects and has remarkable treatment effect, and can be used as a dietary supplement or a health-care food ingredient to prevent and treat anxiety disorder, and promote mental health. It can be seen that the traditional Chinese medicine compound composition is suitable for promotion and application. 1. A traditional Chinese medicine compound composition with anti-anxiety effect , comprising:{'i': 'Paeoniae Radix Alba', '50%-55% by weight of extract;'}{'i': 'Gardeniae Fructus', '20%-40% by weight of extract;'}{'i': 'Albiziae Flos', '15%-30% by weight of extract; and'}{'i': 'Moutan Cortex', '1%-5% by weight of extract.'}2. The traditional Chinese medicine compound composition of claim 1 , comprising:{'i': 'Paeoniae Radix Alba', '52.1% by weight of extract;'}{'i': 'Gardeniae Fructus', '27.0% by weight of extract;'}{'i': 'Albiziae Flos', '18.7% by weight of extract; and'}{'i': 'Moutan Cortex', '2.2% by weight of extract.'}3Paeoniae Radix AlbaGardeniae FructusAlbiziae FlosMoutan CortexPaeoniae Radix Alba, Gardeniae Fructus, Albiziae FlosMoutan CortexPaeoniae Radix AlbaGardeniae FructusAlbiziae FlosMoutan Cortex. The traditional Chinese medicine compound composition of claim 1 , wherein the extract claim 1 , the extract claim 1 , the extract and the extract are separately extracted from and ; and the traditional Chinese medicine compound composition is prepared by compounding the extract claim 1 , the extract claim 1 , the extract and the extract.4. A preparation method of the traditional Chinese medicine compound composition of claim 1 , comprising:{'i': Paeoniae Radix Alba, Gardeniae Fructus, Albiziae Flos', ...

WHOLE GINSENG COMPOSITION USING GINSENG ROOTS, LEAVES AND BERRIES AND METHOD OF PREPARING THE SAME

Disclosed are a red ginseng and/or a red ginseng extract obtained by subjecting (raw) ginseng to ultrasonic treatment and ultrahigh-pressure treatment and then steaming and drying the ginseng, and a method of preparing the same. Also disclosed are a whole ginseng composition including the red ginseng extract prepared by the method, a ginseng leaf extract and a ginseng berry extract, and a method of preparing the same. Advantageously, the red ginseng and the red ginseng extract produced by ultrasonic treatment and ultrahigh-pressure treatment according to the present invention have a lower maximum stress than the conventional red ginseng concentrate in terms of physical properties, reduced inconvenience during ingestion and storage, and increased active ingredient contents. 1. A method of preparing red ginseng comprising:(a) subjecting ginseng (raw ginseng) to ultrasonic treatment and ultrahigh-pressure treatment; and(b) obtaining red ginseng by steaming and drying the ginseng.2. The method of preparing red ginseng of claim 1 , wherein the ultrasonic treatment in step (a) is carried out under the condition of 10 to 200 kHz for 5 minutes to 4 hours and the ultrahigh-pressure treatment in step (a) is carried out under the condition of 200 to 800 MPa for 20 seconds to 10 minutes.3. The method of preparing red ginseng of claim 1 , wherein the steaming in step (b) is carried out at a temperature of 90 to 100° C. for 1 to 5 hours and is repeated one or more times.49.-. (canceled)10. A whole ginseng composition comprising the red ginseng extract prepared by the method of claim 1 , a ginseng leaf extract and a ginseng berry extract.11. The whole ginseng composition of claim 10 , comprising 60 to 95% by weight of the red ginseng extract claim 10 , 3 to 25% by weight of the ginseng leaf extract and 2 to 15% by weight of the ginseng berry extract.12. The whole ginseng composition of claim 10 , wherein the ginseng leaf extract and the ginseng berry extract are obtained by a ...

HYDROLYZED CHICKEN STERNAL CARTILAGE EXTRACT, METHOD FOR PRODUCING THE SAME AND USE THEREOF

The present disclosure relates to pharmaceutical field, providing a hydrolyzed chicken sternal cartilage extract, method for producing the same and use thereof. The hydrolyzed chicken sternal cartilage extract has a type II collagen content of ≥50% and a chondroitin sulfate content of ≥20%. In China, a huge amount of livestock and poultry are consumed, and the total consumption almost reaches ¼ of the worldwide livestock and poultry consumption. Chicken sternal cartilage is one of the main by-products in broiler chicken processing. In the present disclosure, a hydrolyzed chicken sternal cartilage extract rich in type II collagen and chondroitin sulfate is obtained by using biological enzymatic hydrolysis technique. Experiments results show that the hydrolyzed chicken sternal cartilage extract produced by the present disclosure has a good anti-inflammatory effect and can be used to prepare medications for treating osteoarthritis. 1. A hydrolyzed chicken sternal cartilage extract , wherein type II collagen content is ≥50% and chondroitin sulfate content is ≥20%.2. A method for preparing a hydrolyzed chicken sternal cartilage extract , comprisinggrinding chicken sternal cartilage and adding water;adjusting pH to 7.0 and heating to 55° C.;adding alkaline protease and flavourzyme for enzymatic hydrolysis;after inactivating the enzymes, centrifuging and then collecting supernatant; andfiltering the supernatant with cloth and collecting filtrate to obtain a solution of the hydrolyzed chicken sternal cartilage extract.3. The method according to claim 2 , wherein the amount of added water is 2 to 3 times the mass of the chicken sternal cartilage.4. The method according to claim 2 , wherein the amount of added alkaline protease is 0.2% to 0.3% of the mass of the chicken sternal cartilage; and the amount of added flavourzyme is 0.3% to 0.5% of the mass of the chicken sternal cartilage.5. The method according to claim 2 , wherein the mass ratio of the alkaline protease to the ...

Composition, Crocins Active Site, and Uses Thereof

A composition, and a crocins active site extracted from Ellis, mainly comprising the following ingredients: crocetin di-β-D-gentiobioside, crocetin-β-D-glucopyranosyl-β-D-gentiobioside, crocetin di-β-D-glucopyranoside, 13Z-crocetin di-β-D-gentiobioside, neocrocin B, crocetin mono-β-D-gentiobioside, 13Z-crocetin-8-O-β-D-gentiobioside, 13Z-crocetin-8′-O-β-D-gentiobioside, and crocetin mono-β-D-glucopyranoside. Pharmacological experiment results show that the crocins active site can effectively improve learning and memory injuries in mice induced by scopolamine and amyloid β protein. 117-. (canceled)19. The composition according to claim 18 , which further comprises crocetin mono-β-D-gentiobioside.20. The composition according to claim 18 , which further comprises 13Z-crocetin di-β-D-gentiobioside.21. The composition according to claim 18 , which further comprises crocetin-β-D-glucopyranosyl-β-D-gentiobioside.22. The composition according to claim 18 , which further comprises crocetin-β-D-glucopyranosyl-β-D-gentiobioside claim 18 , crocetin di-β-D-glucopyranoside claim 18 , 13Z-crocetin di-β-D-gentiobioside claim 18 , crocetin mono-β-D-gentiobioside claim 18 , 13Z-crocetin-8-O-β-D-gentiobioside claim 18 , 13Z-crocetin-8′-O-β-D-gentiobioside claim 18 , and crocetin mono-β-D-glucopyranoside.24. A crocins active site claim 18 , comprising the composition according to .25Gardenia jasminoides. The crocins active site according to claim 24 , wherein the crocins active site is extracted from Ellis.26. The crocins active site according to claim 24 , wherein a UPLC characteristic chromatogram of the crocins active site comprises 9 chromatographic peaks claim 24 , a retention time of crocetin mono-β-D-gentiobioside is set as 1 claim 24 , and values of relative retention time are obtained for the various chromatographic peaks respectively claim 24 , the retention time of crocetin di-β-D-gentiobioside is 0.38±0.02 claim 24 , the retention time of crocetin-β-D-glucopyranosyl-β-D- ...

Compositions, Methods, and Medical Compositions for Treatment of and Maintaining the Health of the Liver

Compositions and methods for treatment of and maintaining the health of the liver are disclosed that include a mixture of plant extracts, wherein the plant extracts comprise at least one extract, at least one gel powder, and at least one extract. Compositions and methods for treatment of and maintaining the health of the liver are disclosed that include a mixture of plant extracts, wherein the plant extracts comprise at least one extract enriched for at least one polymer or biopolymer, at least one gel powder enriched for at least one chromone, and at least one extract enriched for at least one lignan and organic acid. 138.-: (canceled)39ArtemisiaAloeSchizandra. A composition for treatment of and maintaining the health of the liver , comprising a mixture of plant extracts , wherein the plant extracts comprise at least one extract , at least one gel powder , and at least one extract.40ArtemisiaAloeSchizandra. A composition for treatment of and maintaining the health of the liver , comprising a mixture of plant extracts from an extract enriched for at least one polymer or biopolymer , an gel powder enriched for at least one chromone , and a extract enriched for at least one lignan and organic acid.41ArtemisiaSchizandra. The composition of claim 39 , wherein the extract and the extract are blended in a weight ratio from 4:1 to 1:4.42AloeArtemisiaSchizandra. The composition of claim 39 , wherein the gel powder are further blended with a mixture of and extracts in a weight percentage of about 5% to about 50%.43Artemisia, SchizandraAloe. The composition of claim 39 , wherein the mixture of and leaf gel powder is in a ratio of 8:4:3.44Artemisia. The composition of claim 40 , wherein the extract comprises 0.01% to 99.9% of biopolymers with molecular weight higher than 500.45ArtemisiaArtemisia absinthium, Artemisia abrotanumArtemisia afra, Artemisia annuaArtemisia arborescens, Artemisia asiatica, Artemisia campestris, Artemisia deserti, Artemisia iwayomogi, Artemisia ...

PREPARATION COMPRISING OMEGA-3 FATTY ACID SALTS AND EXTRACTS OF GUM RESINS FROM BOSWELLIA SPECIES

Preparations may include at least one extract of gum resins from species and at least one omega-3 fatty acid salt selected from eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Surprisingly, such combinations of extracts of gum resins from species and polyunsaturated fatty acid salt can cause a marked and unexpected increase in the biosynthesis of specialized pro-resolving mediators (SPM) in a synergistic manner, proposing benefit for resolution of inflammatory conditions. 1. A preparation , comprising{'i': Boswellia', 'Boswellia, 'an extract of one or more gum resins from species as a extract; and'}a polyunsaturated fatty acid salt comprising (i) an omega-3 fatty acid comprising eicosapentaenoic acid (EPA) and/or docosahexaenoic acid (DHA) and (ii) a basic amino acid.2Boswelliacomprises Boswellia serrata, Boswellia carterii, Boswellia papyrifera, Boswellia ameero, Boswellia bullata, Boswellia dalzielii, Boswellia dioscorides, Boswellia elongata, Boswellia frereana, Boswellia nana, Boswellia neglecta, Boswellia ogadensis, Boswellia pirottae, Boswellia popoviana, Boswellia rivae, Boswellia sacraBoswellia. The preparation of claim 1 , wherein the species claim 1 , and/or socotrana.3. The preparation of claim 1 , wherein the extract is prepared by hydro-distillation claim 1 , steam distillation claim 1 , extraction by percolation claim 1 , extraction under ultrasonic waves claim 1 , solvent extraction claim 1 , Soxhlet's extraction claim 1 , supercritical fluid extraction claim 1 , or membrane nanofiltration.4. The preparation of claim 1 , comprising a boswellic acid.5. The preparation of claim 1 , further comprising:acid resin,gum;tetratriterpene acid;Pentacyclic triterpene; incensole acetate;phellandrene;(+)-cis-olibanic acid; and/or(+)-trans-olibanic acid.6. The preparation of claim 1 , wherein the omega-3 fatty acid salts comprises an organic counter ion comprising lysine claim 1 , arginine claim 1 , ornithine claim 1 , and/or choline.7Boswellia. The ...

PROCESS OF MAKING WINE FROM A WHOLE GRAPE BUNCH, PROCESS OF MAKING POMACE JUICE AND POWDER, AND METHOD OF PRODUCING BEVERAGES ON THE BASIS OF JUICE AND POWDER FROM A GRAPE BUNCH

A food composition for human consumption comprising a plurality of grape ingredients, wherein the plurality of grape ingredients comprise ground flesh, seed, stem, and skin from grapes, and wherein the plurality of grape ingredients further comprise a wine comprising one or more KH Wine proteins. 1. A food composition for human consumption comprising:a plurality of grape ingredients,wherein the plurality of grape ingredients comprise ground flesh, seed, stem, and skin from grapes, andwherein the plurality of grape ingredients further comprise one or more KH Wine proteins.2. The food composition of claim 1 , wherein the wine is spray dryed to create a powder.3. A method of treating certain diseases in a patient comprising administering the food composition of to a patient in need thereof claim 1 , wherein the food composition has a concentration of KH Wine protein above 0%.4. The method of claim 3 , wherein KH Wine healthy cells from the KH Wine proteins claim 3 , after administration to the patient claim 3 , send signals to damaged or sick cells claim 3 , thereby triggering synthesis of proteins to transform the damaged or sick cells to become healthy claim 3 ,wherein the KH Wine healthy cells send signals to other undamaged cells to synthesize proteins to protect the other undamaged cells from damage, infection, and from being prone to DNA and other cellular alterations, andwherein the KH Wine healthy cells send signals to the patient's body to produce new cells that are healthy, thereby preventing the new cells from being affected by intracellular and extracellular damaging signals.5. A food composition for human consumption comprising:a plurality of pomace ingredients,wherein the plurality of pomace ingredients comprises ground flesh, seed, stem, and skin from pomace in grapes, andwherein the plurality of pomace ingredients further comprise one or more KH Pomace proteins.6. The food composition of claim 5 , wherein the food composition is a powder claim 5 , juice ...

METHOD OF ISOLATING SPHINGOLIPIDS FROM CORDYCEPS AND THEIR USE

A method of isolating at least one sphingolipid portion selected from a sphingoid base portion, a ceramide portion, a glycosphingolipid portion or a phosphosphingolipid portion from , in particular from wild-type , allows for obtaining sphingolipid portions having an increased amount of one of sphingoid bases, ceramides, glycosphingolipids or phosphosphingolipids. The sphingolipid portions isolated contained significant amounts of sphingolipids not reported so far, and possess exceptional immunosuppressive activities. A method of treating a subject suffering from an inflammatory disease like an autoimmune disease or an allergic disease includes administering sphingolipids isolated from , in particular from wild-type . A method of treating a subject suffering from an inflammatory disease includes administering certain sphingolipids to the subject. Still further in accordance with the present invention is a composition, in particular a pharmaceutical composition comprising at least one sphingolipid portion. 1Cordyceps. A method of isolating at least one sphingolipid portion from selected from a sphingoid base portion , a ceramide portion , a glycosphingolipid portion or a phosphosphingolipid portion comprising steps of:{'i': 'Cordyceps', '(i) subjecting a material to a solvent extraction with at least a first and a second extracting solvent in order to obtain a sphingolipid crude extract, wherein the first and the second extracting solvent independently comprise an aliphatic alcohol and a halogenated hydrocarbon;'}(ii) subjecting the sphingolipid crude extract to at least a first and a second chromatographic separation step for obtaining the sphingolipid portion, which first chromatographic separation step includes liquid chromatography with a stationary phase comprising an unmodified silica and which second chromatographic separation step includes liquid chromatography with a stationary phase comprising silica modified with polar functional groups.2CordycepsCordyceps ...

POWDER FORMULATION HAVING A FUNCTION OF ENHANCING IMMUNITY AND METHOD FOR PREPARING THE SAME

The present disclosure belongs to the field of health care products, disclosing a powder formulation made from inulin, Auricularia, PORTA, LYCII FRUCTUS, MORI FRUCTUS, LONGAN ARILLUS, soy peptide powder, COICIS SEMEN, NELUMBINIS SEMEN and JUJUBAE FRUCTUS. The starting materials of the powder formulation are all from natural Chinese herbal medicine without addition of excipient. In addition, dose required for the powder formulation is small; it is easy to be taken and can be dissolved in water; it is soluble in cold water and can be absorbed quickly. The method for preparing the powder formulation in the present disclosure is simple and suitable for large-scale production. The powder formulation obtained has a good stability, long storage time, good taste. Experiments show that the powder formulation of the present disclosure can significantly enhance immunity, therefore can be used to prepare the health care foods having function on improving immunity. 1. A powder formulation having a function of enhancing immunity , which is made from inulin , Auricularia , PORTA , LYCII FRUCTUS , MORI FRUCTUS , LONGAN ARILLUS , soy peptide powder , COICIS SEMEN , NELUMBINIS SEMEN and JUJUBAE FRUCTUS as starting materials.2. The powder formulation according to claim 1 , wherein the mass ratio of inulin claim 1 , Auricularia claim 1 , PORIA claim 1 , LYCII FRUCTUS claim 1 , MORI FRUCTUS claim 1 , LONGAN ARILLUS claim 1 , soy peptide powder claim 1 , COICIS SEMEN claim 1 , NELUMBINIS SEMEN and JUJUBAE FRUCTUS is (20 to 60): (10 to 15): (10 to 15): (10 to 15): (5 to 10): (5 to 8): (1 to 4): (0.1 to 0.5): (0.1 to 0.5): (0.1 to 0.5).3. The powder formulation according to claim 1 , wherein the mass ratio of inulin claim 1 , Auricularia claim 1 , PORTA claim 1 , LYCII FRUCTUS claim 1 , MORI FRUCTUS claim 1 , LONGAN ARILLUS claim 1 , soy peptide powder claim 1 , COICIS SEMEN claim 1 , NELUMBINIS SEMEN and JUJUBAE FRUCTUS is 20: 15: 10: 15: 5: 8: 1: 0.5: 0.1: 0.5.4. The powder formulation ...

MEDICINAL COMPOSITION OF AMARANTH ORIGIN FOR CARDIOVASCULAR TREATMENT

A medicinal composition having a nitrate enriched extract of Amaranth for the prevention and treatment of myocardial ischemia-reperfusion injury, and for the improvement of cardioprotective health and cardio renal protection. A method for the prevention and treatment of myocardial ischemia-reperfusion injury, method of improving cardioprotective health and cardio renal protection by using the composition having a nitrate enriched extract of Amaranth. 1. A combination composition for oral administration , the combination composition comprising a composition a) comprising a nitrate enriched extract of Amaranth , and a composition b) comprising a bio-enhanced turmeric formulation ,wherein the composition a) comprises:about 0.1% to about 70% nitrates;about 1% to about 40% potassium, and,about 0.1% total oxalic acid, and,wherein the composition b) comprises a curcuminoid mixture and an essential oil of turmeric, wherein the curcuminoid mixture consists of curcumin, demethoxycurcumin and bisdemethoxycurcumin, the essential oil of turmeric comprises about 45% ar-turmerone, and weight ratio of curcuminoid mixture to essential oil of turmeric ranges from about 1:1 to about 99:1, and,wherein the combination composition is administered in a single dosage form comprising both the composition a) and the composition b), or, a dosage form comprising composition a) and a dosage form comprising composition b) are administered separately.2. The combination composition of claim 1 , wherein the nitrate enriched extract of Amaranth comprises:greater than about 3% to about 20% nitrates,about 1% to about 40% potassium, and,about 0.1% total oxalic acid.3. The combination composition of claim 1 , wherein the nitrate enriched extract of Amaranth comprises:greater than about 20% to about 70% nitrates,about 1% to about 40% potassium, and,about 0.1% total oxalic acid.4. The combination composition of claim 1 , wherein the nitrate enriched extract of Amaranth comprises:about 9% nitrates,about 18 ...

SEAWEED EXTRACTS, ISOLATED COMPOUNDS, AND METHODS OF TREATMENT

The instant invention relates to seaweed extract compositions, processes for isolation, isolated active agents, and methods of treating disease, disorders and conditions in a subject, including, reactive oxygen species (ROS)-mediated diseases and diseases mediated through the activation of the Nrf2-ARE (antioxidant response element) pathway, including proliferative diseases and disorders, Alzheimer's disease, stroke, and certain diseases and disorders of aging and associated with aging and exposure, by use of the extracts, compounds, and compositions thereof. 1Cymopolia. An extract from the algae , sp. , isolated by:a) Exposing said algae to a solvent or solvent combination;b) Filtering the material/mixture from step a); andc) Removing the solvent or solvent combination from step b).2. The extract of further comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'a) Purifying the material/mixture from step c) within ; and'}b) Removing the chromatography mobile phase to provide enriched fractions.3. The extract of further comprising screening the extract in an ARE reporter assay.4. The extract of claim 1 , wherein the solvent or solvent combination is selected from the group consisting of ethyl acetate claim 1 , methanol claim 1 , hexanes claim 1 , ethanol claim 1 , isopropanol claim 1 , acetonitrile claim 1 , water claim 1 , and dichloromethane.5. (canceled)6. The extract of claim 1 , wherein the algae comprises one or more compounds selected from:a) (E)-2-bromo-5-(3,7-dimethylocta-2,6-dien-1-yl)benzene-1,4-diol (Cymopol, 1);b) (E)-2-bromo-5-(7-hydroxy-3,7-dimethyloct-2-en-1-yl)benzene-1,4-diol (7-hydroxycymopol, 2);c) 2,6-dibromo-1,1,4a-trimethyl-2,3,4,4a,9,9a-hexahydro-1H-xanthen-7-ol (Cymobarbatol, 3); andd) 5-bromo-2-((3-bromo-2,2-dimethyl-6-methylenecyclohexyl)methyl)-4-methoxyphenol (Cyclocymopol monomethyl ether, 4).7. The extract of claim 1 , wherein the extract comprises one or more compounds selected from:a) (E)-2-bromo-5-(3,7-dimethylocta-2,6-dien-1 ...

MEDICAMENT FOR TREATING STROKE CAUSED BY DEEP FUNGAL INFECTIONS

Use of addition and subtraction of the Banxia Baizhu Tianma Decoction in preparation of medicines or health products for treating strokes caused by deep fungal infections. The present invention relates to the field of medical and health care, and specifically relates to use of chemical ingredients, i.e. alkaloids and volatile oils contained in plant raw materials such as , fresh orange peel and Liquorice to prepare drugs or health products for treating strokes caused by deep fungal infections. 1Gastrodia elataPinellia ternataAtractylodes macrocephalaPoria cocosGastrodia elataPinellia ternataAtractylodes macrocephalaPoria cocosGastrodia elataPinellia ternataAtractylodes macrocephalaPoria cocosGastrodia elataPinellia ternataAtractylodes macrocephalaPoria cocos. A medicine for treating strokes caused by deep fungal infections , characterized in that the active pharmaceutical ingredients of the medicine comprise alkaloids and/or volatile oils extracted from , alkaloids and/or volatile oils extracted from , alkaloids and/or volatile oils extracted from , alkaloids and/or volatile oils extracted from , alkaloids and/or volatile oils extracted from fresh orange peel , and alkaloids and/or volatile oils extracted from Liquorice; methods for preparing the medicine include: taking alkaloids of , alkaloids of , alkaloids of , alkaloids of , alkaloids of fresh orange peel and alkaloids of Liquorice and mixing them in a certain proportion; adding various conventional excipients required to prepare different dosage forms thereto; and preparing pharmaceutically acceptable dosage forms; taking volatile oils of , volatile oils of , volatile oils of , volatile oils of , volatile oils of fresh orange peel and volatile oils of Liquorice and mixing them in a certain proportion; adding various conventional excipients required to prepare different dosage forms thereto; and preparing pharmaceutically acceptable dosage forms; taking alkaloids and volatile oils of , alkaloids and volatile ...

HEPATOPROTECTIVE TRADITIONAL CHINESE MEDICINE COMPOSITION, EXTRACT THEREOF, AND PHARMACEUTICAL USE THEREOF

Disclosed is a hepatoprotective traditional Chinese medicine composition, extract and pharmaceutical use thereof. The composition comprises How, (Leyss. Ex Fr.) Karst., (Fisch) Bge. Var. (Bge) Hsiao, Thunb., Alt. and Bge. The composition and extract thereof may be used for treating liver injury, hepatitis, hepatic fibrosis, hepatic cirrhosis or liver cancer, and they may also be used as a vaccine adjuvant or an immunomodulator. 1Morinda officinalisGanoderma lucidumAstragalus membranaceusmonghlicusRanunculus ternatusSophora flavescensSalvia miltiorrhiza. A traditional Chinese medicine composition , comprising the following components: How , (Leyss. Ex Fr.) Karst. , (Fisch) Bge. Var. (Bge) Hsiao , Thunb. , Alt. and Bge.2Morinda officinalisGanoderma lucidumAstragalus membranaceusmonghlicusRanunculus ternatusSophora flavescensSalvia miltiorrhiza. The traditional Chinese medicine composition as claimed in claim 1 , wherein weight ratios of the components are: 15-35 parts of How claim 1 , 10-20 parts of (Leyss. Ex Fr.) Karst. claim 1 , 25-35 parts of (Fisch) Bge. Var. (Bge) Hsiao claim 1 , 10-20 parts of Thunb. claim 1 , 10-20 parts of Alt. claim 1 , and 10-20 parts of Bge.;{'i': Morinda officinalis', 'Ganoderma lucidum', 'Astragalus membranaceus', 'monghlicus', 'Ranunculus ternatus', 'Sophora flavescens', 'Salvia miltiorrhiza, 'preferably, weight ratios of the components are: 30 parts of How, 15 parts of (Leyss. Ex Fr.) Karst., 30 parts of (Fisch) Bge. Var. (Bge) Hsiao, 15 parts of Thunb., 15 parts of Alt. and 15 parts of Bge.'}3Epimedium brevicornuRehmannia glutinosaAtractylodes macrocephalaCitrus reticulataSedum sarmentosumPueraria lobataHovenia acerbaPueraria lobataLycopus lucidushirtusCurcuma wenyujinTrionyx sinensisDendrobium nobileCremastra appendiculataAbrus cantoniensisCurcuma phaeocaulisScutellaria barbata. The traditional Chinese medicine composition as claimed in or claim 1 , further comprising one or more (e.g. claim 1 , 2-10 claim 1 , e.g. claim 1 , 2-6 ...

FUNCTIONALLY REINFORCED DESALTED NUTRITIONAL COMPOSITIONS FROM HALOPHYTES AND PREPARATION METHOD THEREOF

Disclosed are a functionally reinforced desalted nutritional composition, a desalted extract and a cold-water-extracted salt substitute, which are derived from halophytes that grow in coastal regions under highly saline conditions and thus retain high salt concentrations, as well as the use of the desalted nutritional composition for combating obesity. More particularly, this invention relates to a functionally reinforced desalted nutritional composition, a desalted extract and a salt substitute cold-water-extracted from halophytes that inhabit extreme environments of high salinity under high salt stress, the halophytes being desalted through a cold water extraction process at a low temperature based on the difference in water solubility of salts with change in temperature to allow only sodium chloride to be selectively removed, and the composition thus having decreased sodium content as well as having increased content of useful minerals such as potassium, as well as nutrients and physiologically active substances, which are naturally contained in halophytes. 1. A method of preparing a functionally reinforced desalted nutritional composition from a halophyte , comprising the steps of:(a) mixing dried powder of the halophyte with water at 9° C. or lower and stirring a resultant mixture;(b) centrifuging the stirred mixture and removing a supernatant having a high salt content to recover a desalted precipitate; and(c) drying the desalted precipitate.2. A functionally reinforced nutritional composition from a halophyte , comprising sodium of less than 6.8 wt % and carbohydrates of 61 wt % or greater , based on a dry weight.3. The functionally reinforced nutritional composition from the halophyte as set forth in claim 2 , comprising potassium (K) of 0.1 to 3.0 wt % claim 2 , calcium (Ca) of 0.1 to 2.0 wt % and magnesium (Mg) of 0.1 to 1.5 wt % claim 2 , based on the dry weight.4. The functionally reinforced nutritional composition from the halophyte as set forth in ...

FERMENTATION PRODUCT OF MUNG BEAN HULL AND USES OF THE SAME

A fermentation product of mung bean hull and its uses are provided, wherein the fermentation product is provided by fermenting a mung bean hull and/or an extract of mung bean hull in the present of And, the fermentation product of mung bean hull is used for regulating blood sugar, assisting in regulation of blood pressure, assisting in regulation of blood lipid, preventing hypertension, reducing blood pressure, preventing hypertriglyceridemia, reducing blood lipid, preventing hyperglycemia, reducing blood sugar, preventing cardiovascular disease, treating cardiovascular disease, preventing diabetes, and/or treating diabetes. 1Lactobacillus plantarum.. A fermentation product of mung bean hull , which is provided by fermenting a mung bean hull and/or an extract of mung bean hull in the presence of2. The fermentation product of mung bean hull as claimed in claim 1 , wherein the fermentation is conducted in the presence of an externally added first solvent.3. The fermentation product of mung bean hull as claimed in claim 1 , wherein the extract of mung bean hull is provided by extracting a mung bean hull with a second solvent.4. The fermentation product of mung bean hull as claimed in claim 2 , wherein the first solvent is water.5. The fermentation product of mung bean hull as claimed in claim 3 , wherein the second solvent is water.6. A method for at least one of preventing hypertension claim 1 , reducing blood pressure claim 1 , assisting in regulation of blood pressure claim 1 , preventing hypertriglyceridemia claim 1 , reducing blood lipid claim 1 , assisting in regulation of blood lipid claim 1 , preventing hyperglycemia claim 1 , reducing blood sugar claim 1 , regulating blood sugar claim 1 , preventing cardiovascular disease claim 1 , treating cardiovascular disease claim 1 , preventing diabetes and treating diabetes claim 1 , comprising administering to a subject in need an effective amount of the fermentation product of mung bean hull as claimed in .7. The ...

SOYBEAN SEED EXTRACT, METHOD FOR PRODUCING THE SAME AND USES THEREOF

The invention relates to a soybean seed extract, method for producing the same and uses of the extract of soybean seeds in promoting wound healing, promoting neuron cell proliferation and/or treating brain diseases and/or neurodegenerative diseases, treating breast cancer, reducing side effects of interfering with DNA and/or RNA replication drugs and/or enhancing pharmaceutical effects of interfering with DNA and/or RNA replication drugs. 1. A method for promoting wound healing in a subject in need of such promotion and/or treatment comprising administering to said subject an effective amount of an extract composition comprising a soybean seed extract , which soybean seed extract is prepared by a process comprising steps of:(a) providing soybean seeds and an extracting solution, which extracting solution is water or an alcohol solution containing alcohol at the concentration lower than about 90 wt %;(b) extracting the soybean seeds with the extracting solution at a barometric pressure lower than about 1 atm and at a temperature lower than about 60° C. to obtain an crude extract; and(c) removing solids from the crude extract to obtain a liquid portion.2. The method according to claim 1 , wherein the process for preparing the soybean seed extract further comprises a step (d) of concentrating the liquid portion obtained in the step (c) to obtain a concentrated solid portion.3. The method according to claim 2 , wherein the process for preparing the soybean seed extract further comprises a step (e) of drying the concentrated solid portion obtained in the step (d).4. The method according to claim 1 , further comprising a soybean seed vapor fraction claim 1 , which soybean seed vapor fraction is prepared by a process comprising steps of:(i) providing soybean seeds in a second extracting solution, which second extracting solution is water or an alcohol solution containing alcohol at the concentration lower than about 15 wt %; and(ii) extracting the soybean seeds with the ...

GENTIOPICROSIDE FREE GENTIANA EXTRACT

The present invention relates to gentiopicroside free and/or extracts. Furthermore, it relates to cosmetic compositions comprising such gentiopicroside free or extract, as well as mixtures thereof. 1Gentiana septemfida. A process for the preparation of a Gentiana acaulis and/or extract which is substantially free of gentiopicroside , said process comprising the steps of{'i': Gentiana acaulis', 'Gentiana septemfida, '(i) Extracting the aerial parts (flower, leaf, stem) of and/or with a water/organic solvent mixture to obtain, after filtration, an extract comprising gentiopicroside, followed by'}(ii) Removal of the organic solvent to obtain an aqueous extract, followed by(iii) Hydrolysis of the gentiopicroside in the aqueous extract to gentiopicral.2. The process according to claim 1 , wherein the extraction in step (i) is performed with a water/ethanol mixture.3. The process according to claim 1 , wherein the hydrolysis of gentiopicroside to gentiopicral in step (iii) is done with a β-glucosidase claim 1 , preferably with a β-glucosidase immobilized on an epoxy-activated methacrylic/styrene resin.4. The process according to claim 1 , wherein the hydrolysis is performed until the concentration of gentiopicroside is less than 0.1% claim 1 , preferably less than 0.01% claim 1 , most preferably less than 0.001%.5. The process according to claim 1 , said process containing a step (iv) consisting in removal of gentiopicral from the aqueous extract obtained in (iii) by extraction.6. The process according to claim 5 , wherein the gentiopicral is removed by extraction with an organic solvent claim 5 , preferably with ethyl acetate.7Gentiana acaulisGentiana septemfidaGentiana acaulisGentiana septemfida. The process according to claim 1 , wherein a mixture of aerial parts of and is used in a ratio of to between 5/95 mass/mass and 50/50 mass/mass.8Gentiana acaulisGentiana septemfida. The process according to claim 7 , wherein the ratio of to is comprised between 10/90 mass/mass ...

METHOD FOR ISOLATION OF ALKALOIDS AND AMINO ACIDS, AND COMPOSITIONS CONTAINING ISOLATED ALKALOIDS AND AMINO ACIDS

Described herein are methods to purify alkaloids and amino acids. Also described are compositions and methods to treat or prevent a disease using the purified amino acids and alkaloids. The composition can be, for example, formulated into a beverage, a supplement, or formulated for use in e-cigarettes. Also described are methods of treating a disease such as Parkinson's Disease, Alzheimer's Disease, ADHD, ADD, vascular disorders, cancer, heart disorders, migraine headaches, cluster headaches, plaque reduction or aging using one or more of the purified alkaloids or amino acids. 1. A method for purification of alkaloid , the method comprising:a) preparing a solution comprising at least one alkaloid;b) heating the alkaloid solution to a temperature of at least 145° F. Fahrenheit;c) mixing the alkaloid solution during heating;d) homogenizing the heated alkaloid solution at between 100,000-300,000 revolutions per minute; ande) cooling the mixed alkaloid solution;thereby purifying the alkaloid.2. The method of claim 1 , wherein the alkaloid comprises nicotine claim 1 , caffeine claim 1 , cannabis claim 1 , hemp claim 1 , including hemp oils claim 1 , delta-9-tetrahydrocannabionol (THC) claim 1 , quinine claim 1 , ephedrine claim 1 , homoharringtonine claim 1 , galantamine claim 1 , vincamine claim 1 , morphine claim 1 , chelerythrine claim 1 , piperine claim 1 , psilocin claim 1 , cocaine claim 1 , or theobromine.3. The method of claim 1 , wherein the alkaloid solution is heated for at least five minutes.4. The method of claim 1 , further comprising filtering the cooled alkaloid mixture.5. A composition comprising the purified alkaloid of .6. The composition of claim 5 , wherein the composition comprises a beverage.7. The composition of claim 5 , wherein the composition comprises a supplement.8. The composition of claim 5 , wherein the composition is formulated for use in e-cigarettes.9. A method of treating a disease in an individual comprising administering a ...

ANTIHYPERTENSIVE AGENT

Provided is an antihypertensive agent that is safe and has a mild effect. 1. An antihypertensive agent comprising S-1-propenylcysteine or a salt thereof as an active ingredient.2. The antihypertensive agent according to claim 1 , wherein when a total of a trans-isomer and a cis-isomer is 100% claim 1 , the rate of the trans-isomer in the S-1-propenylcysteine is from 50 to 100%.3Allium. The antihypertensive agent according to claim 1 , wherein the S-1-propenylcysteine or a salt thereof is derived from at least one plant selected from the group consisting of garlic claim 1 , onion claim 1 , elephant garlic claim 1 , Chinese chive claim 1 , and spring onion.4Allium. The antihypertensive agent according to claim 3 , wherein the S-1-propenylcysteine or a salt thereof is obtained by extracting the plant in a 10 to 50% ethanol aqueous solution at 0 to 80° C. for 1 month or more claim 3 , adsorbing the obtained extract to a cation exchange resin claim 3 , eluting the adsorbent with 0.1 to 3 N ammonia water claim 3 , subjecting the eluate to a silica gel column chromatography and/or reverse phase column chromatography claim 3 , and collecting the resulting eluate.5. The antihypertensive agent according to claim 1 , wherein the agent is a medicine.6. The antihypertensive agent according to claim 1 , wherein the agent is a food.7. A food claim 1 , comprising S-1-propenylcysteine or a salt thereof as an active ingredient.810-. (canceled)11. A method for antihypertension comprising administering S-1-propenylcysteine or a salt thereof to a subject in need thereof. The present invention relates to an antihypertensive agent.Recently, due to changes in people's lifestyles (e.g., an increase in lipid intake in dietary life, an increase in drinking and smoking, and a lack of exercise), so-called life-style related diseases, such as diabetes mellitus, hyperlipemia, hypertension, and gout, which are caused by, for example, accumulation of fat or stress and reduction in liver function, ...

Method for preparation of a cannabinoid extract from hemp

The invention relates to a method for extraction and separation of cannabinoids from industrial hemp, designed for medicinal purposes, and also the preparation of an extract, not containing tetrahydrocannabinol, and the preparation of maximum refined individual cannabinoids. The advantage of the method according to the invention consists in the preparation of an extract from hemp, which contains at a high percentage medically useful cannabinoids and doesn't contain undesirable admixtures and tetrahydrocannabinol, so that it can be used without any restrictions as a pharmaceutical. Moreover, the method allows the possibility of separation, if required, into individual useful cannabinoids as pure compounds, in ecological terms, without environmental pollution, as it is according to the most synthetic methods. The possibility of producing pure compounds represents a great contribution to the research of substances, related to a concrete medical application and the preparation of various combinations thereof, with the objective of expansion the field of application. The method is also cost-effective. The method consists in that the extract, obtained in accordance with various methods, undergoes a centrifugal countercurrent liquid-liquid chromatography, as the operation includes a centrifugation of solvents and the extract, obtained during the previous operations; the solvents form two phases, the phase, which the extract is dissolved in, is mobile, and the other one is stationary, whereby the mobile phase passes through the stationary phase, wherein several amounts of the components of the extract content are captured; this passing of the mobile phase through the stationary phase is repeated many times, until separation of the desired substances, which are analyzed in a familiar way, whereby as stationary phase solvents are used, which are selected from the group of straight-chain and branched-chain hydrocarbons, produced from crude oil, straight-chain and/or ...

PHARMACEUTICAL COMPOSITION FOR TREATING ECZEMA AND METHOD FOR PREPARATION THEREOF

A pharmaceutical composition for treating eczema is disclosed. The pharmaceutical composition includes, by weight, 2 to 6 parts of Dried Rhizoma Zingiberis Officinalis, 2 to 6 parts of Paeonia Lactiflora, 1 to 4 parts of Fructus Amomi, 0.5 to 3 parts of Semen Alpiniae Katsumadai, 0.5 to 3 parts of Inula helenium, 0.5 to 3 parts of Radix Et Rhizoma Rhei and 0.5 to 3 parts of Rhizoma Dioscoreae. The components of the pharmaceutical composition synergistically cooperate to clear and disinhibit the liver and gallbladder and clear away damp heat from the body. The pharmaceutical composition can be used to treat skin eczema symptoms caused by metabolic disorders of the liver and gallbladder functions. A method for preparing the pharmaceutical composition is also disclosed. 1. A pharmaceutical composition for treating eczema , comprising , by weight , 2 to 6 parts of Dried Rhizoma Zingiberis Officinalis , 2 to 6 parts of Paeonia Lactiflora , 1 to 4 parts of Fructus Amomi , 0.5 to 3 parts of Semen Alpiniae Katsumadai , 0.5 to 3 parts of Inula helenium , 0.5 to 3 parts of Radix Et Rhizoma Rhei and 0.5 to 3 parts of Rhizoma Dioscoreae.2. The pharmaceutical composition for treating eczema according to claim 1 , comprising claim 1 , by weight claim 1 , 2 to 4 parts of Dried Rhizoma Zingiberis Officinalis claim 1 , 2 to 4 parts of Paeonia Lactiflora claim 1 , 1 to 3 parts of Fructus Amomi claim 1 , 0.5 to 2 parts of Semen Alpiniae Katsumadai claim 1 , 0.5 to 2 parts of Inula helenium claim 1 , 0.5 to 2 parts of Radix Et Rhizoma Rhei and 0.5 to 2 parts of Rhizoma Dioscoreae.3. The pharmaceutical composition for treating eczema according to claim 2 , comprising claim 2 , by weight claim 2 , 3 parts of Dried Rhizoma Zingiberis Officinalis claim 2 , 3 parts of Paeonia Lactiflora claim 2 , 2 parts of Fructus Amomi claim 2 , 1 part of Semen Alpiniae Katsumadai claim 2 , 1 part of Inula helenium claim 2 , 1 part of Radix Et Rhizoma Rhei and 1 part of Rhizoma Dioscoreae.4. The ...

A SYNERGISTIC COMPOSITION AS A PROMOTER OF AUTOPHAGY

The invention relates to a synergistic composition comprising a dry extract of plant of genus and a compound promoting autophagy selected from biotin and R-N1-spermidine or a salt thereof, wherein R is hydrogen or methyl and mixtures thereof. The synergistic compositions according to the invention may be in the form of a topical formulation or oral formulation and is useful as a promoter of autophagy especially in cells of human scalp hair follicles and in promoting hair growth and/or in the treatment of hair thinning or hair loss. 1Galeopsis. A synergistic composition comprising an extract of plant of genus and a compound promoting autophagy selected from R-N-spermidine or a salt thereof , wherein R is hydrogen or methyl , biotin and mixtures thereof.2GaleopsisGaleopsis segetumGaleopsis tetrahit. The synergistic composition of claim 1 , wherein the extract of plant of genus is selected from the species of and and mixtures thereof.3Galeopsis. The synergistic composition of claim 2 , wherein the extract of plant of genus is a dry extract obtained by the process comprising the following steps:{'i': 'Galeopsis;', 'grinding at least one part of the plant of genus'}extracting with a solvent, preferably a physiologically acceptable solvent;filtering the extract;purifying the filtered extract, preferably by eluting in a column with a solvent;drying the purified extract;grinding the dried purified extract; andoptionally adding excipients.4. The synergistic composition of claim 1 , further comprising an excipient comprising a maltodextrin and/or colloidal anhydrous silica gel.5. The synergistic composition of claim 1 , wherein Spermidine is present in the composition in the form of trihydrochloride.6. A topical formulation comprising the synergistic composition according to and at least one excipient suitable for topical administration.7Galeopsis. The topical formulation according to claim 6 , wherein the amount of the extract of plant of genus is in the range of 0.0003% to ...

COMPOSITION FOR ALLEVIATING AND TREATING NARCOLEPSY, CONTAINING FERMENTED RICE BRAN POWDER AS ACTIVE INGREDIENT, AND PREPARATION METHOD THEREFOR

A composition for alleviating and treating narcolepsy, contains a fermented rice bran powder as an active ingredient. The fermented rice bran powder can be obtained by mixing rice bran with a specific strain and fermenting the resulting mixture, and the composition exhibits cranial nerve stimulation and causes no cognitive impairment, thereby exhibiting an effect of waking a sleeping person, and thus can solve psychological and social problems caused by excessive daytime sleepiness and prevent feelings of shame, difficulty in interpersonal relationships, a decline in work performance and a risk of accidents. In addition, the composition is not neurocytotoxic, and thus can achieve only a desired effect without side effects. 1. A method for preparing a fermented rice bran powder , the method comprising: a) obtaining a fermented rice bran broth by mixing rice bran with one or more strains and fermenting the resulting mixture; b) purifying the fermented rice bran broth , and then vacuum-concentrating the purified fermented rice bran broth; c) obtaining only solid matter by slurrying or recrystallizing the vacuum-concentrated fermented rice bran broth; and d) obtaining a fermented rice bran powder by drying the solid matter and crushing the dried solid matter.2Lactobacillus buchneri, Lactobacillus paracaseitolerans, Lactobacillus harbinensis, Saccharomycopsis fibuligeraPichia kudriavzevii.. The method of claim 1 , wherein the strain in Step a is one or more selected from the group consisting of subsp. and3. The method of claim 1 , wherein the fermentation in Step a is performed under a temperature condition of 35 to 40° C. for 46 to 50 hours.4. The method of claim 1 , wherein the purification process in Step b is performed on the fermented rice bran broth using a mixture of water and an alcohol in chromatography comprising one or more adsorptive resins selected from an epoxy resin and a copolymer of styrene and divinyl benzene.5. The method of claim 4 , wherein in the ...

Tobacco Leaf Extract and Use Thereof for the Treatment of Tobacco Addiction

The invention relates to a tobacco leaf extract containing, relative to the total weight of the extract, at least 5 wt.-% proteins essentially free of molecules with a molecular mass of less than 10 kDa. The invention also relates to a pharmaceutical composition containing such an extract and to the use thereof in the treatment of tobacco addiction. 1. A tobacco leaf extract containing at least 5% by weight , based on the total weight of the dry extract , of proteins of molecular mass greater than 10 kDa and essentially free of molecules of molecular mass less than 10 kDa , said proteins being preferably chosen from the group consisting of the following protein families: lignin-forming anionic peroxidase , glucan endo-1 ,3-beta-glucosidase , endochitinase , pathogenesis-related protein , osmotin and proteinase inhibitor and mixtures thereof.2. The tobacco leaf extract according to claim 1 , characterized in that it is essentially free of high molecular mass proteins.3. The tobacco leaf extract according to claim 1 , characterized in that it is essentially free of proteins whose molecular mass is greater than 500 kDa claim 1 , preferably whose molecular mass is greater than 400 kDa claim 1 , more preferably whose molecular mass is greater than 300 kDa claim 1 , preferentially whose molecular mass is greater than 200 kDa claim 1 , more preferentially whose molecular mass is greater than 150 kDa claim 1 , even more preferentially whose molecular mass is greater than 100 kDa and better still whose molecular mass is greater than 50 kDa.4. The tobacco leaf extract according to claim 1 , characterized in that the content of molecules of molecular mass less than 10 kDa is less than 5% by weight based on the total weight of the extract claim 1 , preferably less than 2.5% by weight claim 1 , and better still less than 1% by weight.5. The tobacco leaf extract according to claim 1 , characterized in that it is obtainable by a solvent extraction process claim 1 , for example an ...

Medicinal Composition of Amaranth Extract Origin Having Enriched Nitrate Content and a Method of Preparing the same

An extract of Amaranth, having enriched nitrate content, L-arginine, Flavonoids, saponins, alkaloids, carbohydrates, proteins, potassium, and with negligible amount of oxalic acid or oxalate content. The extract of Amaranth can be prepared from fresh or dried leaves and stem of Amaranth. Dosage forms of extract include fast melt tablet, lozenge, candy, chewing gum, beverage, tablet, capsule, pill, and powder. The extract of Amaranth enhances nitric oxide concentration, enhances nitrate level concentration, and enhances nitrite level in blood as well as in saliva. Administering the extract can lower blood pressure, increase physical endurance, increase swimming endurance, increase running endurance, and improve sexual performance among human beings. 1. An extract of Amaranth , the extract comprisingabout 0.1% to about 20% nitrates;about 0.1% to about 10% of L-arginine;about 0.001% to about 10% of flavonoids;about 0.01% to about 15% of saponins;about 0.01% to about 10% of alkaloids;about 10% to about 30% of carbohydrates;about 5% to about 25% of proteins;about 5% to about 25% potassium; and,about 0.01% to about 50% of total oxalic acid, wherein the total oxalic acid comprises free oxalic acid and oxalates.2. The extract of Amaranth of further comprising a second extract selected from the group consisting of amla extract claim 1 , turmeric extract claim 1 , grape seed extract claim 1 , green tea extract claim 1 , pomegranate extract claim 1 , cocoa extract claim 1 , coconut root extract claim 1 , rosemary extract claim 1 , mint leaf extract claim 1 , star anise claim 1 , sweet basil extract claim 1 , cinnamon extract/clove extract claim 1 , ginger extract claim 1 , cumin seed extract claim 1 , black pepper extract claim 1 , fenugreek extract claim 1 , and combinations thereof.3. The extract of Amaranth of further comprising Vitamin C.4Amaranthus caudatus, Amaranthus cruentus, Amaranthus tricolor, Amaranthus blitum, Amaranthus viridis, Amaranthus dubius. The extract of ...

BITTER GANODERMA LUCIDUM SPORE POWDER AND PREPARATION METHOD THEREOF

Disclosed is a method for preparing bitter spore powder, and relates to the field of drugs or health care products. The method includes: removing visible impurities from spores, conducting ice bath and heating extraction, filtering through a microfiltration membrane, sterilizing by drying, and conducting sporoderm disruption to obtain the bitter spore powder. The preparation method effectively improves the content of the bitter substances in the spore powder by removing shriveled spores through multiple times of impurity removal and filtration in combination with the manner of conducting sporoderm disruption after extraction. Taking the total triterpenoids in the spores as a representative of the bitter substances, the content of the total triterpenoids can reach 5-8%. Meanwhile, the preparation method can also make the content of polysaccharides reaching 6-10%. 1Ganoderma lucidum. A method for preparing bitter spore powder according to claim 18 , comprising the following steps:{'i': 'Ganoderma lucidum', '(1) removing visible impurities from spores;'}{'i': Ganoderma lucidum', 'Ganoderma lucidum', 'Ganoderma lucidum, '(2) ice bathing the spores obtained in step (1), then mixing the ice-bathed spores with water, and heating the mixture at 90-100° C. for 1.5-3 h to obtain a suspension of spores;'}{'i': 'Ganoderma lucidum', '(3) filtering the suspension of spores obtained in step (2) through a microfiltration membrane, and collecting the filter residue with a particle diameter of more than 5 μm and the filtrate with a particle diameter of less than 1 μm;'}(4) mixing the filter residue and filtrate obtained in step (3), and then drying and sterilizing the mixture; and{'i': 'Ganoderma lucidum', '(5) conducting sporoderm disruption of the material sterilized in step (4) to obtain the bitter spore powder.'}2Ganoderma lucidumGanoderma lucidumGanoderma lucidumGanoderma lucidum. The method for preparing bitter spore powder according to claim 1 , wherein the impurity removal ...

Pharmaceutical composition for treatment of depression and preparation method thereof

Disclosed is a pharmaceutical composition for the treatment of Depression, wherein the pharmaceutical composition is comprised of the following herbs in weight parts: 2-10 parts Ramulus Cinnamomi, 2-10 parts Rhizoma Zingiberis, 2-10 parts Fructus Schisandrae Chinensis, 2-8 parts Semen Ziziphi Spinosae, 2-8 parts Radix Codonopsis, 1-3 parts Rhizoma Dioscoreae, 0.5-2.5 parts Flos Inulae, 1-3 parts Caulis Bambusae in Taenia, 1-3 parts Fructus Trichosanthis, 1.5-4 parts Caulis Polygoni Multiflori, 1.5-4 parts Radix Ophiopogonis, 2-8 parts Radix Rehmanniae, 1.5-4 parts Cortex Moutan Radicis, 0.5-2.5 parts Fructus Gardeniae, 0.5-2.5 parts Herba Lophatheri, and 0.2-1.5 parts Folium Sennae. Also disclosed is a method for preparing the pharmaceutical composition as described above for treatment of depression.

METHOD OF PREVENTING OR IMPROVING UV-INDUCED SKIN DAMAGE USING HYDROANGENOL AS ACTIVE INGREDIENT

Provided is a method for preventing or improving UV-induced skin damage of a subject in need thereof, which comprises administering to the subject an effective amount of a composition containing hydrangenol derived from the extract of as an active ingredient. The composition containing hydrangenol derived from the extract of is able to increase secretion of hyaluronic acid and procollagen type-1 and inhibit secretion of MMP-1 in skin cells, and therefore effective in preventing or improving UV-induced damage of skin cells. Accordingly, the hydrangenol-containing composition is usefully available as a quasi-drug, drug, food, or cosmetic composition. 2Hydrangea serrata.. The method as claimed in claim 1 , wherein the hydrangenol is isolated from an extract of leaf of3Hydrangea serrata,. The method as claimed in claim 2 , wherein the hydrangenol is obtained by ethanol extraction of leaf of ethanol or methanol solvent fractionation claim 2 , and recrystallization.4. The method as claimed in claim 1 , wherein the hydrangenol is contained in an amount of 0.0001 to 10 wt. % with respect to the total weight of the composition.5. The method as claimed in claim 1 , wherein the hydrangenol accelerates proliferation of skin cells damaged by UV radiation claim 1 , reduces production of MMP-1 claim 1 , and increases production of procollagen and hyaluronic acid.6. The method as claimed in claim 1 , wherein the composition is used to moisturize the skin irritated by UV radiation or improve wrinkles.7. The method as claimed in claim 1 , wherein the composition is for oral administration and has at least one dosage form selected from the group consisting of tablet claim 1 , granule claim 1 , pill claim 1 , capsule claim 1 , liquid claim 1 , chewable gel claim 1 , and gum.8. The method as claimed in claim 1 , wherein the composition is for topical administration on the skin and has at least one dosage form selected from the group consisting of toner claim 1 , essence claim 1 , ...