СПОСОБ ЭЛЕКТРОПЛАЗМЕННОГО НАПЫЛЕНИЯ БИОСОВМЕСТИМЫХ ПОКРЫТИЙ НА ОСНОВЕ МАГНИЙСОДЕРЖАЩЕГО ТРИКАЛЬЦИЙФОСФАТА

Изобретение относится к области медицины, в частности, к стоматологии, и раскрывает способ нанесения керамических биосовместимых покрытий. Способ характеризуется тем, что включает предварительную подготовку поверхности имплантата воздушно-абразивной обработкой и ультразвуковым обезжириванием, далее проводят электроплазменное напыление подслоя из титана и биосовместимого слоя, ультразвуковое обезжиривание проводят в водном растворе ПАВ при температуре до 40°C в течение 5-7 мин, электроплазменное напыление подслоя титана производят с дистанции напыления 120-150 мм в течение 12-15 с, при расходе плазмообразующего газа 20 л/мин, дисперсности не более 150 мкм и токе дуги 350 А, электроплазменное напыление порошка магнийсодержащего трикальцийфосфата производят с дистанции напыления 50-60 мм в течение 10-12 с, расход плазмообразующего газа составляет 20 л/мин, дисперсность составляет не более 90 мкм и ток дуги 350 А. Изобретение может быть использовано в челюстно-лицевой хирургии и травматологии ...

BIOACTIVE CONTINUOUS IMPLANTS

REMINERALISIERENDE DENTAL ADHESIVE FILM

MAGNESIUM-SUBSTITUTED HYDROXYL APATITES

HYDROXYL APATITE MATERIAL AND A PROCEDURE FOR ITS PRODUCTION

TRANSLUCENT RADIOPAKE GLASS CERAMICS

COMPOSITION FOR THE TREATMENT OF DENTIN HYPERCSENSITIVITY

BONE CEMENT.

COMPOSITIONS FOR IN SITU MANUFACTURE CALCIUM PHOSPHATE MINERALS.

FILLING MATERIAL.

APATITE GLASS CERAMIC.

MAGNESIUM AMMONIUM PHOSPHATE CEMENTS, THEIR PRODUCTION AND USE

MATERIAL FOR THE REMINERALISIEREN OF ORGANOMINERALGEWEBEN

SINTERED HYDROXYAPATITZUSAMMENSETZUNGEN AND PROCEEDING FOR THEIR PROCESSING

Tooth-surface-membrane-forming powder containing sintered apatite

The present invention provides: hydroxyapatite, a principal component of teeth, which has a high degree of hardness, is to be used in a device for forming a membrane on a tooth surface by spraying the tooth surface with a powder, and is favorable for forming a membrane having an extremely low solubility in acid in a short period of time and favorable for forming a membrane from a powder that conforms to the color tone of the tooth in a short period of time; and a membrane-forming powder that uses hydroxyapatite having a color tone modifier added thereto. The present invention produces: a hydroxyapatite powder sintered at 600-1,350°C in an inert gas atmosphere; a powder obtained by subjecting the hydroxyapatite powder sintered at 600-1,350°C to plasma exposure, or to plasma exposure and the application of mechanical energy; and a membrane-forming powder obtained by adding a color tone modifier to these hydroxyapatite powders.

DENTAL RESTORATIVE MATERIALS

A composition for dental restoration including a dental restorative material and an effective amount for dental remineralisation of a casein phosphopeptide(CPP)-amorphous calcium phosphate (ACP) complex or casein phosphopeptide(CPP)-amorphous calcium fluoride phosphate (ACFP) complex. Also disclosed is a kit of parts comprising a glass ionomer dental cement and (b) a CPP-ACP complex and/or a CPP-ACFP complex, together with instructions for their use for the preparation of the above composition.

IN SITU CALCIUM PHOSPHATE MINERALS -- METHOD AND COMPOSITION

Calcium phosphate minerals are formed by using phosphoric acid substantially free of uncombined water in conjunction with a calcium source, normally as any combination of carbonate, phosphate and hydroxide, and, as required, any additional base to neutralize the phosphoric acid. Protein may be optionally added. The resulting product is readily formed and then sets to a hard, stable, workable shaped object.

PIT AND FISSURE SEALANT FOR TEETH

DENTAL IMPLANT AND MANUFACTURING METHOD THEREOF

The object of the present invention is to provide an implant that enables functional periodontium formation around the implant after transplantation of a dental implant. The dental implant of the present invention is characterized in that a tooth germ tissue-derived or a periodontal membrane tissue-derived cell mass is placed on the surface of the implant, the surface of the implant on which the cell mass is to be placed is the whole or a part of the surface which is surrounded by the alveolar bone of the recipient at the time of implant transplantation.

GLASS COMPOSITIONS AND IT CONTAINING BONDING AGENTS.

BONE CEMENT.

COMPOSITIONS FOR DENTAL CEMENT.

BIOACTIVE CONTINUOUS IMPLANTS.

ARTIFICIAL TEETH FOR ANTERIOR TEETH PORTIONS.

COMPOSITION, CONTAINING THEOBROMINE, AND THEIR APPLICATION FOR TREATMENT OF HYPERSENSITIVITY TEETH

Growing crystaline structures on demand

An apparatus comprising a substrate having a surface with at least one crystallization nucleation site located thereon. The apparatus further comprises a second substrate having a second surface. The second surface is configured to maintain a crystallization starting material in an amorphous state or an initial crystalline state. The crystallization nucleation site is configured to impose a property on the crystallization starting material.

High-strength, translucent mg-high quartz mixed crystal glass ceramics

BIOLOGICALLY ACTIVE PERMANENT IMPLANTS FOR TISSUE REPLACEMENT HARD AND FOR INSERTING AND FIXING ON THE CARRIER SYSTEM AND MOTION OF THE HUMAN BODY

DISPERSIONS Of HYDROXYAPATITE INCLUDING/UNDERSTANDING a STABILIZING AGENT has FONCTIONPHOSPHORYLE, SULPHINYL OR CARBOXYL, AND THEIR METHOD OF PREPARATION

Biodegradable, implantable, malleable formulation with calcium phosphate

L'invention concerne des formulations à base de produits implantables pour obtenir des matériaux formés in situ ou en extemporané à partir de mélange d'ingrédients plus ou moins rapidement résorbables. Les matériaux obtenus sont malléables ou passent par un stade malléable et sont principalement destinés à une utilisation dentaire ou orthopédique pour le comblement osseux. Un mélange d'hydroxylapatite ou d'apatite contenant d'autres phosphates de calcium ou de la chaux avec de l'acide lactique et de l'eau donne une pâte malléable qui durcit par la suite. Un mélange gélatine-apatite-glycérol-eau donne par traitement à basse pression une éponge osseuse de densité et dureté variables. Ces matériaux sont utiles pour fabriquer des obturateurs fémoraux ou pour combler des défauts dans le but de favoriser la régénération osseuse.

Calcium granular phosphate cement and method for its production

Un ciment granulaire de phosphate de calcium contient des poudres mixtes obtenues par mélangeage du phosphate tertiaire de calcium du type alpha ou du phosphate quaternaire de calcium avec un composé de phosphate de calcium choisi dans le groupe comprenant le phosphate primaire de calcium, le phosphate secondaire de calcium et leurs mélanges dans un rapport molaire Ca/P de 1,35 à 1,49 ou de 1,30 à 1,90. Le diamètre minimal de chaque granulé de ciment est de 0,1 à 1,0 mm.

Dental root canal filling material comprises base substance such as gutta-percha and non-miscible particles, preferably of hydroxyapatite

La présente invention conceme une matière d'obturation des canaux radiculaires des dents, caractérisée en ce qu'elle est composée d'un mélange d'une pâte de base d'obturation, du type gutta-percha et de particules non-miscibles dans la pâte de base désignées également « macro-charge » et en ce que ces particules présentent une taille et une forme déterminées adaptées en fonction de la dimension de la préparation apicale.

Production of apatite ceramics, especially for biomedical use

L'invention concerne un procédé de fabrication d'une céramique apatitique, en particulier pour usage biologique. Ce procédé consiste à préparer un mélange homogène de poudres capable de former une hydroxyapatite de formule Ca10(PO4)6 (OH)2 stoechiométrique ou non-stoechiométrique, contenant éventuellement d'autres additifs, à compacter le mélange sous une pression de 100 à 500 MPa à la température ambiante, et à le soumettre à un traitement hydrothermal à basse température (100 à 500°C), en présence d'eau, dans une enceinte étanche.

System for making a dental filling material or implant material, and powder material, [...] hydration, implant material and method of obtaining a bond

Apatite compositions

The present invention relates to an apatite composition comprising 0.001 - 99.999 wt.% of an apatite and 0.001 - 99.999 wt.% of a glass carbomer, based on the total weight of the apatite composition. The apatite is preferably a fluoroapatite according to the general formula (I): wherein: M is a cation other than Ca2+, B is an anion other than P043", A is F", 0≤ x≤ 9, 0≤ y≤ 5, and 0≤ z≤ 2, and most preferably Ca10(PO4)6F2. The apatite composition is advantageously used as a dental filling material, a denting bonding cement, a bone cement, a bone replacing material, in dental care and cleansing products, glass- ceramics, bone scaffolds and bone substrates, and as a coating material for crowns and bridges.

DENTAL PROSTHETIC MATERIAL AND PREPARATION METHOD THEREFOR

A method for preparing a dental prosthetic material comprises the following steps: (1) soaking a tooth enamel, dentin or titanium sheet by using a phosphoric acid aqueous solution or a mixed aqueous solution of peroxide and phosphoric acid; and (2) adding an aqueous solution of phosphate ions and fluorine ions into an Agarose-Ca solution to obtain a mixed solution, and placing the tooth enamel, the dentin or the titanium sheet treated by step (1) into the mixed solution and obtaining the material on the tooth enamel, the dentin or the titanium sheet after the reaction is completed, the Agarose-Ca solution being an aqueous solution of the agarose and calcium nitrate. A method for preparing a tooth prosthetic and whitening material comprises the following steps: (1) soaking a tooth enamel, dentin or titanium sheet by using a phosphoric acid aqueous solution or a mixed aqueous solution of peroxide and phosphoric acid; and (2) placing the tooth enamel, dentin or titanium sheet treated by step ...

HIGH STRENGTH BIOLOGICAL CEMENT COMPOSITION AND USING THE SAME

A hydraulic cement for biomedical applications. The cement sets in-situ, hardening when exposed to water to produce nano-dispersed composite of calcium-silicate-hydrate gel mixed with hydroxyapatite. In comparison with prior cements, the composition provides high biocompatibility, high bioactivity and high biomechanical strength, due to the composite structure of the calcium silicate hydrate reinforced with co-precipitated particles of hydroxyapatite. Biocompatibility is also increased due to an absence of aluminum and magnesium in the composition. The cement is suitable for variety of applications, including dental implants, bone fixation, and bone repair.

HOMOGENEOUS, STORAGE-RESISTANT DISPERSIONS

The invention relates to homogeneous, storage-resistant dispersions of calcium salts that are poorly soluble in water and/or polymers with at least one surfactant.

Rod shaped apatite crystals having a specific length-to-width ratio

The rod-shaped apatite crystals of the formula Ca5(PO4)3(OH)xFy have the following features a) the length-to-breadth ratio of the crystals is at least ≧5 and b) x+y=1, where if x or y≠0 the total amount of the crystals is present as a mixture of individual hydroxyapatite crystals and fluoroapatite crystals and/or as mixed crystals, such that, based on the total amount of the crystals, (1−x)·100% of the hydroxide ions present if y=0 are replaced by fluoride ions. The invention furthermore describes dispersions which contain such rod-shaped apatite crystals, and a process for the preparation of the dispersions or of the apatite crystals.

Leucite based glass ceramic containing nanoscale metallic oxide powder

Die Erfindung betrifft eine mit nanoskaligem Metalloxid dotierte Leucit-Glaskeramik, ein zu ihrer Herstellung geeignetes dotiertes Leucit-Glaskeramik-Pulver, Verfahren zur Herstellung der dotierten Leucit-Glaskeramik, ihre Verwendung als Dentalmaterial, ein sie umfassendes Dentalprodukt und die Verwendung der nanoskaligen Metalloxid-Pulver zur Herstellung der dotierten Glaskeramik bzw. des dotierten Leucit-Glaskeramik-Pulvers.

USE OF BONE GLUE FOR SEALING AN APICAL FORAMEN

CERAMIC MATERIAL FOR FILLINGS AND/OR DENTURE AND PROCEDURE FOR THE PRODUCTION OF THE SAME

CALCIUM PHOSPHATE CEMENT

FABRIC STANDS ZUSAMENSETZUNGEN FOR THE TREATMENT OF TOOTH ILLNESSES

DENTALE COMPOSITIONS WITH CALZIUMPHOSPHORFREISETZENDEM GLASS

CHEMICALLY BOUND BIOLOGICAL MATERIAL WITH CUSTOM-MADE CHARACTERISTICS

PLASTIFIZIERBARES IMPLANT MATERIAL

Tooth-surface-membrane-forming powder containing sintered apatite

The present invention provides: hydroxyapatite, a principal component of teeth, which has a high degree of hardness, is to be used in a device for forming a membrane on a tooth surface by spraying the tooth surface with a powder, and is favorable for forming a membrane having an extremely low solubility in acid in a short period of time and favorable for forming a membrane from a powder that conforms to the color tone of the tooth in a short period of time; and a membrane-forming powder that uses hydroxyapatite having a color tone modifier added thereto. The present invention produces: a hydroxyapatite powder sintered at 600-1,350°C in an inert gas atmosphere; a powder obtained by subjecting the hydroxyapatite powder sintered at 600-1,350°C to plasma exposure, or to plasma exposure and the application of mechanical energy; and a membrane-forming powder obtained by adding a color tone modifier to these hydroxyapatite powders.

Implant surface composition

An implant structure or parts thereof having a surface composition obtainable through an anodic oxidation process is disclosed. The surface composition comprising titanium oxide in the anatase crystalline phase and at least 90% of the pores have an orifice with a mean inside diagonal distance of less than 0,1 μm. It is also disclosed an implant system comprising said surface composition and a method of obtaining said surface.

INDUCED REMINERALISATION OF HUMAN TOOTH ENAMEL

... ²The present application relates to the induced ²remineralization of human tooth enamel and in ²particular to the building up of apatite on tooth ²material.²² ...

COMPOSITION FOR RESTORING DEFECTS IN CALCIFIED TISSUES

A composition for restoring defects in calcified tissues comprises an amorphous bioactive particulate consisting essentially of calcium, silicon and oxygen. Said agent may be selected from the group consisting of : a) a reaction product of an organic silicate source and a source of calcium; b) a calcium containing hydrolysis product of tetraethylorthosilicate; c) a calcium containing silica sol-gel; d) a binary calcium oxide and silicate precipitated material; e) a synthetic analog of a naturally occurring wollastonite-like calcium silicate; and f) a precipitated reaction product of soluble calcium source and a silicate solution. A process for producing the amorphous bioactive particulate consists essentially of adding a sufficient amount of a solution of a soluble calcium source to a solution of a silicate or silicate precursor to cause a precipitation of calcium-containing silicate particulate.

DENTAL RESTORATIVE MATERIALS

The present invention relates to a composition for dental restoration including a dental restorative material and an effective amount of a casein phosphopeptide(CPP)-amorphous calcium phosphate (ACP) complex or casein phosphopeptide(CPP)-amorphous calcium fluoride phosphate (ACFP) complex.

PHARMACEUTICAL COMPOSITION AND PROCESS

PHARMACEUTICAL COMPOSITION AND PROCESS A b s t r a c t The invention relates to a combination useful for the substitution of bone defects having pathologically developed or being artificially established as well as compositions containing these combinations. The combinations of the invention preferably contain in a weight ratio of 1:9 to 9:1, most preferably 1:1 porous hydroxylapatite and/or tricalcium phosphate in relation to 7-isopropoxyisoflavone, optionally in the form of discrete granules of the active ingredients. The composition contains 7-isopropoxyisoflavone applied onto the surface of porous hydroxylapatite and/or tricalcium phosphate. An advantageous member of the combination according to the invention is 7-isopropoxyisoflavone (generic name: ipriflavone) known as an anti-osteoporotic drug.

Artificial tooth and process for producing the same

Dental caries prevention composition and preparation method thereof

CIMENTS DENTAIRES A BASE D'OXYDE METALLIQUE ET D'UN DERIVE D'ACIDE TANNIQUE

L'INVENTION A POUR OBJET UNE COMPOSITION POUR CIMENTS DENTAIRES. ELLE COMPREND UN PREMIER INGREDIENT DONT LE COMPOSANT PRINCIPAL EST UN OXYDE METALLIQUE ET UN SECOND INGREDIENT CAPABLE DE REAGIR AVEC LE PREMIER POUR FORMER UNE MASSE DURCIE, ET CONTENANT EN OUTRE UN DERIVE D'ACIDE TANNIQUE PEU SOLUBLE DANS L'EAU, UN AGENT REDUCTEUR SOLUBLE DANS L'EAU ET EVENTUELLEMENT UN SEL D'ALUMINIUM.

IMPLANTS PERMANENTS BIOLOGIQUEMENT ACTIFS

IMPLANTS PERMANENTS BIOLOGIQUEMENT ACTIFS, CARACTERISES EN CE QU'ILS SONT CONSTITUES PAR UNE MATIERE CERAMIQUE VITREUSE BIOLOGIQUEMENT ACTIVE POUVANT ETRE TRAVAILLEE MECANIQUEMENT ET AYANT LA COMPOSITION PONDERALE SUIVANTE, EN : SIO 29,5 A 32,5, ALO 14,5 A 17,5, MGO 14,5 A 16,5, NAO 2,0 A 3,0, KO 5,5 A 6,5 F 5,0 A 6,0, CAO 13,0 A 15,O, PO 10,0 A 12,O, ET PAR LES PHASES CRISTALLINES SEPAREES CONSTITUEES PAR 50 A 80 EN VOLUME DE MICA ET PAR 15 A 20 EN VOLUME D'APATITE.

BIOLOGICALLY ACTIVE PERMANENT IMPLANTS FOR the HARD FABRIC REPLACEMENT AND INSERTION AND FIXING ON the CARRIER SYSTEM AND LOCOMOTOR OF the Human body

PASTE Of OBTURATION PULPODENTAIRE.

PROCESS FOR the PRODUCTION Of a POWDER

L'invention concerne un procédé pour la production d'une poudre. Une suspension contenant des particules agglomérées d'une matière synthétique est produite en faisant réagir des première et seconde matières et est ensuite séchée. Le diamètre des particules agglomérées est ajusté par la puissance d'agitation. Application : Obtention d'une poudre dont la résistance peut être ajustée.

TEETH COATING LIQUID

광화 플루오라이드 조성물

... 본 발명은 치아 표면, 특히 치아 법랑질을 광화 하기 위한 조성물에 관한 것이다. 또한, 본 발명은 치아 우식증, 치아 부식 및 불소증에 의해 유발된 치아 법랑질 내의 (표면 아래 병변을 포함하는) 저광화된 병변을 광화하는 방법도 제공한다.

COMPOSITIONS CONTAINING POLYVINYL PYRROLIDONE FOR TREATING DENTAL PULP AND FILLING ROOT CANALS

Improved compositions for treating dental pulp and root canals comprising a mixture of particulate materials with water-based liquids containing polyvinyl pyrrolidone are provided. Homopolymers and copolymers of polyvinyl pyrrolidone can be used. Optionally, the composition may contain surfactants, humecatants, stabilizers, and other additives. Examples of particulate powders include mixtures of calcium silicate, calcium aluminate, calcium sulfate, and hydroxyapatite. The compositions are particularly suitable for sealing and obturating dental root canals and root apices. The composition provides a stable barrier to bacterial and fluid leakage in the root canal system of a tooth.

PRODUCTION OF SHAPED DENTAL PARTS COMPOSED OF POROUS GLASS

The invention relates to a blank for producing shaped dental parts which consists entirely of porous glass without crystalline material. The density of the blank is in the range from 50% to 95% of its theoretical density. It has a disc-like shape having a diameter of at least 20 mm. The blank is produced by a process in which glass powder is firstly pressed at a pressure in the range from 10 MPa to 300 MPa and this green body is (pre)sintered at a temperature in the range from 580°C to 750°C to give a blank composed of porous glass without crystalline material. Monolithic shaped dental parts can be obtained from the resulting blank by mechanical machining and subsequent sintering, with a process according to the invention being employed to stabilize the shape of the shaped parts. The glass preferably contains: SiO2 50 - 80% by weight, Al203 3 - 24% by weight, K2O 3-13% by weight, Na2O 3-13% by weight, Li2O 0-4% by weight, B2O3 0-4% by weight, F 0-4% by weight, TiO2 0-8% by weight, ZrO2 ...

CERAMIC TOOTH REPLACEMENT AND METHOD FOR THE PRODUCTION THEREOF

The invention relates to a tooth replacement, particularly a composite crown or composite bridge, comprising two independent components, i.e. an inner frame structure (1) and an outer facing cover (3), which are joined together by means of a connector material (2). Also disclosed is a method for producing said tooth replacement.

SINTERED HYDROXYAPATITE COMPOSITIONS AND METHOD FOR THE PREPARATION THEREOF

La présente invention concerne un matériau hydroxyapatite fritté renforcé qui comprend de l'hydroxyapatite (Ca¿10(PO¿4)¿6(OH)¿2), un verre biocompatible à base de CaO et de P¿2O¿5 contenus dans des proportions inférieures à 10 % du poids d'hydroxyapatite, et une source d'ions F-¿.

Calcium phosphate cement precursors

A mixture of two or more calcium phosphate compositions are combined with an aqueous solution and are useful as bone fillers on bone cements such as orthopedic and dental cements and remineralizers. The mixtures self-harden to substantially form hydroxyapatite, the mineral phase of bone and tooth enamel. The at least one or more of precursors is prepared in a manner resulting in its having an extremely low moisture level. The use of low moisture components results in an improved shelf life to the mixture.

Li2O-Al2O3-SiO2 crystallized glass and method of its production

Li2O-Al2O3-SiO2 crystallized glass is provided which has clarity and glass characteristics equivalent to or superior to a conventional crystallized glass, even when the content of As2O3 is decreased. The Li2O-Al2O3-SiO2 crystallized glass contains, by weight, 0.05 to 4% Sb2O3, wherein the content of ß-OH is 0.3 to 4/mm, and a ß-quartz solid solution or a ß-spodumene solid solution is produced as a main crystal.

Calcium phosphate cements and calcium phosphate cement compositions

A calcium phosphate cement or the like which shows a low viscosity and excellent handleability in the step of kneading and achieves a high strength of the hardened body even though a kneading liquid is used in a small amount. A calcium phosphate cement containing a polysaccharide powder and 0.05 to 5% by weight of an N-alkyl-D-glucamine such as N-methyl-D-glucamine; or a calcium phosphate cement containing a calcium phosphate powder and a specific alkanolamine such as monoethanolamine. A calcium phosphate cement composition containing a calcium phosphate powder and a kneading liquid comprising an aqueous solution containing 0.1 to 10% by weight of an N-alkyl-D-glucamine such as N-methyl-D-glucamine or a kneading liquid containing a definite amount of a specific alkanolamine such as monoethanolamine.

SINTERED HYDROXYAPATITE COMPOSITIONS AND METHOD FOR THE PREPARATION THEREOF

A sintered enhanced hydroxyapatite material which comprises hydroxyapatite (Ca10(PO4)6(OH)2), a biocompatible glass based upon CaO and P2O5 contained in an amount of less than 10 % by weight based on the weight of hydroxyapatite, and a source of F- ions.

DEODORIZING/ANTIFOULING COMPOSITION FOR DENTAL PRODUCT

A dental resin material mixed with a composition containing, as a maincomponent, titanium dioxide whose surface has been partly coated with apatite. In the dental resin material, it is preferable that anatase-, rutile-, brookit-type titanium dioxide or a mixture of these components is used as the titanium dioxide. The apatite for partial coating of titanium dioxide is produced by immersing powdery titanium dioxide in a pseudo body fluid and stirring the immersed titanium dioxide approximately at the same temperature as a human body temperature, i.e., 36 °C. In this instance, it is important that the apatite is deposited in the form of platy crystals of less than 2 mm in thickness to cover 0.001 - 10 % of the surface of titanium dioxide.

CERAMIC MATERIAL FOR TOOTH FILLINGS AND/OR PROSTHESES AND PROCESS FOR PRODUCING THE SAME

In order to avoid the known disadvantages especially of amalgam as tooth filling material, hydroxyl apatite ceramic material have already been tried. Because they are accompanied by demineralisation phenomena and are difficult to produce, however, these materials are not very widely used. The disclosed ceramic material, in particular based on hydroxyl apatite, has a good remineralisation performance and is easy to produce. For that purpose, it has at least two different phases or crystals. On the one hand, it has relatively insoluble calcium phosphate compounds, in particular hydroxyl apatite and hydroxyl apatite compounds. On the other hand, it consists of easily soluble substances, such as alpha- and/or beta-tricalcium phosphate. The latter is dissolved in the course of time out of the hydroxyl apatite matrix. It thus leaves behind a lattice of pores, into which the calcium phosphate-containing saliva is is diffused, so that the pores are gradually closed by hydroxyl apatite. This ceramic ...

Process to prepare moulded shaped translucent lithium-di-silicate glass ceramic products

Self-hardenable material

PREPARATION OF MOLDED TRANSLUCENT LITHIUM DISILICATE GLASS CERAMIC PRODUCT

PROBLEM TO BE SOLVED: To obtain a molded translucent lithium disilicate glass ceramic product used as a dental repairing material by press machining or milling in a plastic state by producing a glass melt contg. specified amts. of SiO2, Al2O3, La2O3, MgO, ZnO and Li2O, molding and cooling the melt and carrying out heat treatment. SOLUTION: A glass melt contg., by weight, 57.0-80.0% SiO2, 0-5.0% Al2O3, 0.1-6.0% La2O3, 0.5-0% MgO, 0.8-0% ZnO, 11.0-19.0% Li2O, 0.1-7.0% Al2O3+La2O3, and 0.1-9.0% MgO+ZnO is molded and cooled. The molded glass product is heat-treated at 400-1,100°C to obtain the objective glass ceramic product in a blank form. This product is hardly reacted with an investment material used at the time of press machining in a plastic state. The product is plastically molded at 700-1,200°C and 8-40 bar pressure or machined to obtain the desired geometric glass ceramic product. COPYRIGHT: (C)1999,JPO ...

SELF-HARDENING CALCIUM PHOSPHATE CEMENTS AND PROCEDURES FOR THEIR PRODUCTION AND USE

BONE SPARE MATERIAL AND PROCEDURE FOR ITS PRODUCTION

REPAIR MATERIAL FOR HARD FABRIC

PROCEDURE FOR THE PRODUCTION ONE HYDROXYAPATIT CONTAINING BIOLOGICAL MATERIAL, MANUFACTURED BIOLOGICAL MATERIAL AND SURGICAL OR ZAHNÄRTZLI APPLICATION

COMPOSITION FOR IMPLANTATION INTO THE HUMAN AND ANIMAL BODY

DENTALGLASKERAMIKEN

BIOACTIVE CONTINUOUS IMPLANTS

GLASS-CERAMIC MATERIAL WITH APATITE CRYSTAL PHASE - IN PARTICULAR FOR PROTHETI PURPOSES - AND PROCEDURE FOR THE PRODUCTION OF SUCH GLASS-CERAMIC MATERIAL

DENTALE RESTORATION MATERIALS

Dental implant and method for producing same

... [Problem] The purpose of the present invention is to provide a dental implant which enables the formation of a functional periodontal tissue around the implant after the implantation of the implant. [Solution] The dental implant according to the present invention is characterized in that a cell mass originated from a tooth germ tissue or a periodontal ligament tissue is placed on the surface of the implant and the surface of the implant on which the cell mass is to be placed is the whole or a part of a surface that is surrounded by an alveolar bone of a recipient during the implantation of the implant.

Mineralization fluoride compositions

The present invention relates to compositions for mineralizing a dental surface, in particular tooth enamel. Methods of mineralizing hypomineralized lesions (including subsurface lesions) in the tooth enamel caused by dental caries, dental corrosion and fluorosis are also provided.

ROD SHAPED APATITE CRYSTALS WITH A SPECIFIC LENGTH-TO-WIDTH RATIO

The invention relates to rod-shaped apatite crystals of formula Ca5(PO4)3(OH)xFy, comprising the following characteristics: a) the length-to- width-ratio of the crystal is at least >= 5 and b) x + y represent 1, in the case where x or y 0, the total amount of the crystals exist as single hydroxylapatite crystals and fluorapatite crystals and/or as a mixture of mixed crystals, whereby in relation to the total amount of the crystals, (1 - x). 100 % of the hydroxidions are replaced by fluoridions in the case where y = 0. The invention also relates to dispersions which contain said rod-shaped apatite crystals, in addition to a method for producing said dispersions or apatite crystals.

COMPOSITIONS FOR TREATING TOOTH AND/OR BONE TISSUE

The invention relates to compositions for treating tooth and/or bone tissue that contain calcium phosphates, calcium fluorides or calcium fluorophosphates, all of which being poorly soluble in water, and polyelectrolytes. The compositions can be cured and are suited for the smoothing, the reconstruction, and the remineralizing treatment of tooth and bone tissue, especially for eliminating microroughnesses.

INDUCED REMINERALISATION OF HUMAN TOOTH ENAMEL

The invention relates to the induced remineralisation of human tooth enamel and in particular the build up of apatite on tooth material.

DENTAL TREATMENTS

DISPERSIONS Of HYDROXYAPATITE INCLUDING/UNDERSTANDING an ACID AMINE As AGENTSTABILISANT, AND a THEIR METHOD OF PREPARATION

MANUFACTORING PROCESS Of a CERAMICS APATITIQUE, IN PARTICULAR FOR USAGEBIOLOGIQUE

BIOMATERIAL OF FILLING OSSEOUS OR DENTAL, AND PROCEEDED OF PREPARATION.

Process for connection between two materials, by fusion obtained by means of a laser beam, applicable in dentistry

NOUVEAUX COMPOSES MINERAL/ORGANIQUE, PROCEDE DE FABRICATION, ET POLYMERES PREPARES A PARTIR DE CEUX-CI

L'INVENTION CONCERNE UN PROCEDE DE FABRICATION DE COMPOSES MINERALORGANIQUE CONSTITUES DE CRISTAUX MINERAUX ET DE CHAINES ORGANIQUES FIXEES PAR COVALENCE EN SURFACE DESDITS CRISTAUX. CE PROCEDE CONSISTE A INTRODUIRE LES GROUPEMENTS PHOSPHATES DE MOLECULES ORGANIQUES PHOSPHORYLEES DANS LES TUNNELS D'UNE STRUCTURE APATITIQUE EN COPRECIPITANT A) LESDITES MOLECULES ORGANIQUES PHOSPHORYLEES, B) DES ANIONS MINERAUX DONT L'ANION ORTHOPHOSPHATE, C) PAR DES CATIONS ALCALINO-TERREUX, ALCALINS OU DE TERRES RARES,DONT LE CATION CALCIUM. CES ANIONS ET CATIONS SONT CHOISIS DE NATURE CHIMIQUE TELLE QU'ILS CONDUISENT A DES CRISTAUX DE STRUCTURE APATITIQUE. LE PHOSPHATE DES MOLECULES ORGANIQUES S'INSERE DANS LE TUNNEL DE LA STRUCTURE APATITIQUE, CEPENDANT QUE LA CHAINE ORGANIQUE DE CHAQUE MOLECULE S'ETEND A L'EXTERIEUR DU CRISTAL, DEMEURANT LIEE PAR LIAISON COVALENTE AU GROUPEMENT PHOSPHATE INSERE DANS LE TUNNEL.

IMPLANTS PERMANENTS BIOLOGIQUEMENT ACTIFS POUR LE REMPLACEMENT DE TISSUS DURS ET POUR L'INSERTION ET LA FIXATION SUR LE SYSTEME PORTEUR ET LOCOMOTEUR DU CORPS HUMAIN

IMPLANTS PERMANENTS BIOLOGIQUEMENT ACTIFS, CONSTITUES PAR UNE MATIERE CERAMIQUE VITREUSE BIOLOGIQUEMENT ACTIVE POUVANT ETRE TRAVAILLEE MECANIQUEMENT ET AYANT LA COMPOSITION PONDERALE SUIVANTE, EN : SIO 29,5 A 32,5, ALO 14,5 A 17,5, MGO 14,5 A 16,5, NAO 2,0 A 3,0, KO 5,5 A 6,5, F 5,0 A 6,0, CAO 13,0 A 15,0, PO 10,0 A 12,0, ET PAR LES PHASES CRISTALLINES SEPAREES CONSTITUEES PAR 50 A 80 EN VOLUME DE MICA ET PAR 15 A 20 EN VOLUME D'APATITE POUR LE REMPLACEMENT DE TISSUS DURS ET POUR L'INSERTION DE LA FIXATION SUR LE SYSTEME PORTEUR ET LOCOMOTEUR DU CORPS HUMAIN.

Application and manufactoring process of a plastic plate-support on plates and dental synthetic matter prostheses containing acrylic resin

METHOD OF TREATING A PATIENT'S TEETH USING FLUORIDE RELEASING GLASS COMPOSITION

A method of treating sensitive teeth includes (1) attaching a fluoride releasing glass composition to a person's tooth, and (2) allowing fluoride to be slowly released over time in order to reduce chronic and/or acute tooth sensitivity. A preferred glass composition comprises the general empirical formula given below, expressed in approximate weight percent of the element: P: 16-24, F: 5-30, O: 20-44 and at least one of Na, K, Li, or Al in an amount up to a total of about 40 weight percent and optionally, up to about 5 weight percent of boron and/or silicon. © KIPO & WIPO 2007 ...

MULTIPHASE TISSUE COMPLEX SCAFFOLDS

Multiphase tissue engineered tissue complex scaffolds and methods for their use are provided. 1. A multiphase tissue engineered scaffold comprising:a non-mineralized ligament phase with a folded, accordion-like structure; andone or more mineralized phases adjacent to the non-mineralized ligament phase.2. The multiphase tissue engineered scaffold of comprising:a non-mineralized ligament phase with a folded, accordion-like structure; andfirst and second mineralized phases adjacent to the non-mineralized ligament phase.3. The multiphase tissue engineered scaffold of wherein the non-mineralized ligament phase comprises polymer nanofibers.4. The multiphase tissue engineered scaffold of wherein the polymer nanofibers have a selected architecture and/or comprise a blend of polymers optimal for periodontium tissue complex regeneration.5. The multiphase tissue engineered scaffold of wherein the polymer nanofibers comprise PLGA claim 3 , PLA or PGA.6. The multiphase tissue engineered scaffold of wherein the polymer nanofibers comprise polycaprolactone (PCL).7. The multiphase tissue engineered scaffold of wherein the polymer nanofibers comprise a blend of PLGA claim 3 , PLA and/or PGA and PCL.8. The multiphase tissue engineered scaffold of wherein the polymer nanofibers are aligned.9. The multiphase tissue engineered scaffold of wherein the polymer nanofibers are unaligned.10. The multiphase tissue engineered scaffold of wherein the one or more mineralized phases comprise polymer nanofibers and a ceramic.11. The multiphase tissue engineered scaffold of wherein the one or more mineralized phases comprise polymer nanofibers and hydroxyapatite or a calcium phosphate.12. The multiphase tissue engineered scaffold of wherein the polymer nanofibers comprise PLGA claim 11 , PLA or PGA.13. The multiphase tissue engineered scaffold of wherein the polymer nanofibers comprise polycaprolactone (PCL).14. The multiphase tissue engineered scaffold of wherein the polymer nanofibers comprise a ...

Dental Devices

The present invention is a dental device comprising natural and sustainable materials. These materials are derived from the nut of the tangua palm tree that may be fashioned into devices for human and animals when replacing one or more teeth of the subject. 1. A dental device comprising a chewing surface:the chewing surface comprising a naturally derived material;wherein the naturally derived material is derived from a vegetable nut.2. The dental device of claim 1 , wherein the naturally derived material comprises an endosperm of Tagua palm nut.3. The dental device of claim 1 , wherein the hardness of the naturally derived material is from about 2.5 to about 4 on the Mohs Hardness Scale.4. The dental device of claim 2 , wherein the naturally derived material comprises a coating of hydroxylapatite.5. The dental device of claim 1 , wherein the device is selected from the group consisting of a bridge claim 1 , a full denture claim 1 , a partial denture claim 1 , a crown claim 1 , a cap claim 1 , and combinations thereof.6. The dental device of claim 5 , wherein the device is a crown.7. The dental device of claim 6 , wherein the naturally derived material matches the color or texture claim 6 , or both color and texture of a human tooth.8. (canceled)9. A method for making a dental device comprising the steps of:a. matching a material derived from a tree nut to a tooth for color or texture;b. milling the material derived from the tree nut to a desired shape, size, or shape and size to form a chewing surface of a dental device.1013-. (canceled)14. The method of claim 9 , further comprising combining the material derived from a tree nut with an additional material.1516-. (canceled)17. A biocompatible composite material comprising:a material derived from a tree nut; andhydroxylapatite.18. The composite material of wherein the material derived from the tree nut is a dehydrated Tagua nut endosperm.19. The composite material of wherein the composite material is in a shape ...

APATITE COMPOSITIONS

The present invention relates to an apatite composition comprising 0.001-99.999 wt. % of an apatite and 0.001-99.999 wt. % of a glass carbomer, based on the total weight of the apatite composition. The apatite is preferably a fluoroapatite according to the general formula (I): wherein: M is a cation other than Ca, B is an anion other than P04″, A is F″, 0≦x≦9, 0≦y≦5, and 0≦z≦2, and most preferably Ca(PO)F. The apatite composition is advantageously used as a dental filling material, a denting bonding cement, a bone cement, a bone replacing material, in dental care and cleansing products, glass-ceramics, bone scaffolds and bone substrates, and as a coating material for crowns and bridges. 131-. (canceled)33. The apatite composition according to claim 32 , wherein the apatite is a fluoroapatite.35. The apatite composition according to claim 34 , wherein x=y=0 and z=2.37. The apatite composition according to claim 36 , wherein x=y=z=0 and A is OH.38. The apatite composition according to claim 32 , wherein the poly(dialkylsiloxane) is linear or cyclic.39. The apatite composition according to claim 38 , wherein the alkyl groups of the poly(dialkylsiloxane) are methyl groups.40. The apatite composition according to claim 38 , wherein the poly(dialkylsiloxane) has a kinematic viscosity in the range of about 1 to about 100 claim 38 ,000 cSt at 25° C.41. The apatite composition according to claim 32 , wherein the particles of the fluorosilicate glass powder have an average size of about 10to about 200 μm.42. The apatite composition according to claim 32 , wherein the aqueous acid solution comprises an inorganic acid or an organic acid.43. The apatite composition according to claim 32 , wherein the fluoroapatite composition is in a particulate form.44. The apatite composition according to claim 43 , wherein the particles of the fluoroapatite composition have an average size of about 10to about 200 μm.45. A dental filling material comprising the apatite composition according to ...

Apatite Forming Biomaterial

The present invention relates to chemically bonded ceramic biomaterials, especially a dental material or an implant material. The main binder system forms a chemically bonded ceramic upon hydration thereof, and comprises powdered calcium aluminate and/or calcium silicate, and phase(s) to secure apatite formation at a pH close to neutrality. A second binder system—a cross-linking organic binder system which provides for initial crosslinking of the freshly mixed paste is advantageously added. The invention relates to a powdered composition for preparing the inventive chemically bonded ceramic biomaterial, and a paste from which the biomaterial is formed, as well as a kit comprising the powdered composition and hydration liquid, as well as methods and use of the biomaterial in dental and implant applications with the aim of remineralisation, integration and bone repair.

LITHIUM SILICATE GLASSES OR GLASS CERAMICS, METHOD FOR PRODUCTION THEREOF AND USE THEREOF

The invention relates to glass ceramics based on the lithium metasilicate system (LiO SiO(LiSiO)), which are mechanically processible in a simple manner in an intermediate stage of the crystallization and, after complete crystallization, represent a high- strength, highly translucent and chemically stable glass ceramic. 115-. (canceled)16. A lithium silicate glass or glass ceramic having the following composition:{'sub': '2', '50 to 70 wt-% SiO,'}{'sub': '2', '15 to 22 wt-% LiO,'}{'sub': 2', '2, '8 to 20 wt-% of a stabilizer selected from ZrOand/or HfO,'}{'sub': 2', '2, '0.1 to 4 wt-% KO and/or NaO,'}{'sub': 2', '3, '0.1 to 4 wt-% AlO, and'}2 to 8 wt-% additives.17. The glass or glass ceramic of with the following composition:{'sub': '2', '50 to 64 wt-% SiO,'}{'sub': '2', '17 to 20 wt-% LiO,'}{'sub': 2', '2, '8 to 20 wt-% of a stabilizer selected from ZrOand/or HfO,'}{'sub': 2', '2, '1 to 3 wt-% KO and/or NaO,'}{'sub': 2', '3, '1 to 3 wt-% AlO, and'}4 to 6 wt-% additives.18. The glass or glass ceramic of with the following composition:{'sub': '2', '55 to 64 wt-% SiO,'}{'sub': '2', '10 to 20 wt-% LiO,'}{'sub': 2', '2, '8 to 20 wt-% of a stabilizer selected from ZrOand/or HfO,'}{'sub': 2', '2, '0 to 5 wt-% KO and/or NaO,'}{'sub': 2', '3, '0.1 to 5 wt-% AlO, and'}0 to 10 wt-% additives.19. The glass or glass ceramic of with the following composition:{'sub': '2', '50 to 60 wt-% SiO,'}{'sub': '2', '10 to 20 wt-% LiO,'}{'sub': 2', '2, '8 to 20 wt-% of a stabilizer selected from ZrOand/or HfO,'}{'sub': 2', '2, '1 to 5 wt-% KO and/or NaO,'}{'sub': 2', '3, '0.1 to 5 wt-% AlO, and'}0 to 10 wt-% additives.20. The glass or glass ceramic of with the following composition:{'sub': '2', '55 to 64 wt-% SiO,'}{'sub': '2', '10 to 20 wt-% LiO,'}{'sub': 2', '2, '10 to 20 wt-% of a stabilizer selected from ZrOand/or HfO,'}{'sub': 2', '2, '0 to 5 wt-% KO and/or NaO,'}{'sub': 2', '3, '0.1 to 5 wt-% AlO, and'}0 to 10 wt-% additives.21. The glass or glass ceramic of with the following ...

Deposition of Discrete Nanoparticles on an Implant Surface

A method of forming a nanocrystalline surface on an implant is disclosed. The method comprises the act of roughening at least a portion of the implant surface to form a roughened surface. The method further comprises the act of, without forming an alkoxide on the roughened surface, depositing nanocrystals on the roughened surface. The nanocrystals comprise a material having a property that promotes osseointegration. 123-. (canceled)24. A dental implant made of a material comprising titanium comprising:a head portion having a non-rotational feature;a lowermost end opposing the head portion;a threaded bottom portion for engaging bone between the head portion implant and the lowermost end; anda nanocrystalline surface formed on at least a portion of the implant, the nanocrystalline surface including discrete nanocrystals deposited on a roughened surface of the implant, the roughened surface including at least one of a grit-blasted surface or an acid-etched surface, wherein a portion of the roughened surface is exposed between at least some of the discrete nanocrystals such that the exposed roughened portion between the discrete nanocrystals is capable of contacting bone.25. The dental implant of claim 24 , wherein the nanocrystals comprise a material that promotes osseointegration.26. The dental implant of claim 24 , wherein the implant is made of commercially pure titanium.27. The dental implant of claim 24 , wherein the discrete nanocrystals include hydroxyapatite nanocrystals having dimensions on the order of about 20 nanometers to about 100 nanometers.28. The dental implant of claim 24 , wherein the roughened surface includes titanium hydroxide and/or titanium oxide.29. The dental implant of claim 28 , wherein the discrete nanocrystals are directly bonded to the titanium hydroxide and/or titanium oxide.30. The dental implant of claim 24 , wherein the roughened surface that receives the discrete nanoparticles is free of an alkoxide and a tri-functional silane.31. A ...

Compositions for endodontic procedures

An adhesion promoter for endodontic sealant compositions for filling and sealing a root canal.

DENTAL TREATMENT METHOD AND ABUTMENT USED THEREIN

A dental treatment method is provided. In this method, a tooth of a patient is extracted and prepared to provide a root part. A root canal in the extracted tooth is prepared and treated. A post of an abutment is fitted into the root canal to attach the root part to the abutment. The abutment having the root part is attached to a dental implant. With the root part attached to the abutment, periodontal connective tissue maintains the jaw bone associated with the extracted tooth, without significant hard tissue loss. 111.-. (canceled)12. A method of manufacturing an abutment for a dental implant , the method comprising:obtaining data associated with the dentition of a patient;generating a model of the abutment through a computer-implemented process based on the data; andprocessing a material based on the model to generate the abutment, wherein the abutment is configured to match the analogue of a predetermined tooth of the patient, such that, after the predetermined tooth is extracted and prepared to provide a root part, the root part is attached to the abutment during osseointegration.13. The method of manufacturing an abutment of claim 12 , wherein the data used is based on the average human tooth size and shape claim 12 , such that the abutment can be prefabricated.14. The method of manufacturing an abutment of claim 12 , further comprising cleaning and preserving the abutment.15. An abutment for a dental implant claim 12 , the abutment comprising:an apical end and a coronal end opposite the apical end;an insertion portion at the apical end, the insertion portion being configured to be received in an opening of the dental implant;a transition portion coronal of the insertion portion; anda connecting portion extending coronally of the transition portion, wherein the connecting portion is configurable to be attached to a root canal or tooth structure of an extracted tooth of a patient.16. The abutment of claim 15 , wherein the insertion portion comprises an anti- ...

Calcium phosphate sintered particles and production method therefor

This invention has an object to provide a means for providing a calcium phosphate sintered body particle group that does not cause a phenomenon of bubble generation in any use mode thereof, and further has a smaller particle diameter. There is provided a ceramic particle group containing spherical ceramic particles, which is characterized in that the ceramic particle has a particle diameter within a range of 10 nm to 700 nm, and is a calcium phosphate sintered body particle, and further the ceramic particle group contains no calcium carbonate.

Production of Dental Shaped Parts

The invention discloses a process for producing dental shaped parts which consists entirely of porous glass without crystalline portions. The density of the blank is between 50% and 95% of its theoretical density. It has a discoidal shape with a diameter of at least 20 mm. The blank is produced by a process in which glass powder is first pressed at a pressure of between 10 MPa and 300 MPa and this green body is (pre-)sintered at a temperature of between 580° C. and 750° C. to form a blank of porous glass without crystalline portions. From the obtained blank, monolithic dental shaped parts can be obtained by mechanical processing followed by sintering, wherein a process according to the invention for stabilizing the shape of the shaped parts is used.

MINERALIZATION FLUORIDE COMPOSITIONS

The present invention relates to compositions for mineralizing a dental surface, in particular tooth enamel. Methods of mineralizing hypomineralized lesions (including subsurface lesions) in the tooth enamel caused by dental caries, dental corrosion and fluorosis are also provided. 1. A composition for mineralizing a dental surface or sub-surface comprising calcium monofluorophosphate and a mineralizing agent.2. A composition according to claim 1 , wherein the calcium monofluorophosphate is in an amount of about 200 ppm to about 5000 ppm F.3. A composition according to claim 2 , wherein the calcium monofluorophosphate is in an amount of about 400 ppm to about 1500 ppm F.4. A composition according to claim 3 , wherein the calcium monofluorophosphate is in an amount of about 1000 ppm to about 1450 ppm F.5. A composition according to any one of to claim 3 , wherein the mineralizing agent is stabilized amorphous calcium phosphate (ACP) and/or amorphous calcium fluoride phosphate (ACFP).6. A composition according to any one of to claim 3 , wherein the composition is selected from the group consisting of a toothpaste claim 3 , toothpowder claim 3 , liquid dentifrice claim 3 , mouthwash claim 3 , mouthrinse claim 3 , mouth spray claim 3 , varnish claim 3 , dental cement claim 3 , troche claim 3 , chewing gum claim 3 , lozenge claim 3 , dental paste claim 3 , gingival massage cream claim 3 , gargle tablet claim 3 , dairy product and other foodstuffs.7. A composition according to claim 6 , wherein the composition is a toothpaste.8. A composition according to claim 6 , wherein the composition is a varnish.9. A composition according to claim 6 , wherein the composition is a dental cement.10. A composition according to claim 6 , wherein the composition is a mouthwash.11. A composition according to any one of to claim 6 , for use in a domestic animal claim 6 , companion animal or zoo animal.12. A method of mineralizing a dental surface or sub-surface comprising contacting the ...

DENTAL TREATMENT METHOD AND ABUTMENT USED THEREIN

A dental treatment method is provided. In this method, a tooth of a patient is extracted and prepared to provide a root part. A root canal in the extracted tooth is prepared and treated. A post of an abutment is fitted into the root canal to attach the root part to the abutment. The abutment having the root part is attached to a dental implant. With the root part attached to the abutment, periodontal connective tissue maintains the jaw bone associated with the extracted tooth, without significant hard tissue loss. 1. A dental treatment method comprising:extracting a tooth of a patient;preparing the extracted tooth to provide a root part having autologous tissue attached thereon;attaching the root part to an abutment; andconnecting the abutment to a dental implant.2. The dental treatment method of claim 1 , further comprising cleaning and sterilizing the abutment prior to the attaching the root part to the abutment.3. The dental treatment method of claim 1 , further comprising rinsing the extracted tooth and subsequently storing the rinsed tooth in a tissue culture medium at room temperature for at least 30 minutes to preserve the vitality of the autologous tissue.4. The dental treatment method of claim 1 , wherein the autologous tissue comprises periodontal connective tissue.5. The dental treatment method of claim 4 , wherein the periodontal connective tissue comprises periodontal ligament cells.6. The dental treatment method of claim 1 , wherein the attaching the root part to the abutment comprises preparing and treating a root canal of the extracted tooth and inserting a post of the abutment into the root canal.7. The dental treatment method of claim 6 , wherein the attaching the root part to the abutment further comprises cementing the post within the root canal after inserting the post of the abutment into the root canal.8. The dental treatment method of claim 6 , wherein the attaching the root part to the abutment comprises threading the post of the abutment ...

Dental enamel compositions with anti-inflammatory agents

Provided are methods and compositions relating to a dental composition more specifically to prepare the damaged dentin of the tooth prior to repair. The dental compositions include a bioactive glass and a non-aqueous solvent comprising an alcohol, anti-inflammatory and anti-pain reliver.

Production of Dental Shaped Parts Composed of Porous Glass

The invention discloses a blank for producing dental shaped parts which consists entirely of porous glass without crystalline portions. The density of the blank is between 50% and 95% of its theoretical density. It has a discoidal shape with a diameter of at least 20 mm. 1. Blank for producing dental shaped parts , characterized in that it consists entirely of porous glass without crystalline portions , wherein the density of this porous blank is between 50% and 95% of the theoretical density of a densely-sintered blank , and in that it has a disc-like shape with a diameter of at least 20 mm.2. Blank according to claim 1 , characterized in that the density of the blank is between 55% and 85% of the theoretical density of the blank.6. Blank according to claim 1 , characterized in that the diameter of the disc-like shape is at least 50 mm.7. Blank according to claim 1 , characterized in that the thickness of the disk is more than 5 mm.8. Blank according to claim 1 , characterized in that it has at least one holding means for clamping the blank during the processing thereof to form a dental shaped part claim 1 , wherein the holding means is a holding means provided on the outer circumference of the blank.9. Process for producing the blank according to claim 1 , characterized in that glass powder is pressed at a pressure of between 10 and 300 MPa to form a green body and said green body is presintered at a temperature of between 580° C. and 750° C. to form a blank made of porous glass without crystalline portions.10. Process for stabilizing the shape of a monolithic dental shaped part during its production claim 1 , wherein this production comprises at least one sintering step claim 1 , characterized in that the monolithic shaped part is connected to at least one support structure or to at least one support mould during at least one time segment within the duration of the sintering claim 1 , such that the change in shape of the shaped part during this time segment is ...

ENAMEL PRODUCTS AND METHODS OF USE

Described herein are three-dimensional (3D) culture systems that can be used to produce enamel organoids that generate enamel products. The invention features methods of culturing a variety of cell types to produce such enamel organoids; the organoids themselves; enamel products generated by the organoids; and methods of fashioning the enamel products into surgical restorations, including dental restorations and other prostheses. 1. A method of generating an enamel product in vitro , the method comprising:(a) providing a differentiated cell in cell culture;(b) exposing the differentiated cell to an agent that induces dedifferentiation, thereby producing a dedifferentiated cell;(c) exposing the dedifferentiated cell to a serotonin receptor agonist, thereby producing an ameloblast-like cell that produces an extracellular matrix comprising amelogenin; and(d) exposing the extracellular matrix to a composition that induces mineralization, thereby producing an enamel product.2. A method of generating an enamel product in vitro , the method comprising:(a) providing a stem cell or precursor cell in cell culture;(b) exposing the stem cell or precursor cell to a serotonin receptor agonist, thereby producing an ameloblast-like cell that produces an extracellular matrix; and(c) exposing the extracellular matrix to a composition that induces mineralization, thereby producing an enamel product.3. The method of claim 1 , wherein the differentiated cell is an epithelial cell.45.-. (canceled)6. The method of claim 1 , wherein the agent that induces dedifferentiation is a transforming growth factor.7. (canceled)8. The method of claim 1 , wherein the dedifferentiated cell expresses N-cadherin and octamer-binding transcription factor 4 (Oct-4) but does not express E-cadherin.9. (canceled)10. The method of claim 1 , wherein the serotonin receptor agonist is serotonin claim 1 , an azapirone claim 1 , a triptan claim 1 , LY-334 claim 1 ,370 claim 1 , lasmiditan claim 1 , lysergic acid ...

IMPLANTABLE COMPOSITE CONTAINING CARBONATED HYDROXYAPATITE

Provided is an implantable composite which includes a plurality of resorbable ceramic particles with or without a biodegradable polymer. The resorbable ceramic particles can be granules including carbonated hydroxyapatite and tricalcium phosphate in a ratio of 5:95 to 70:30. Some resorbable ceramic particles are granules, which include carbonated hydroxyapatite and p tricalcium phosphate in a ratio of 5:95 to 70:30. The resorbable ceramic particles have a particle size from about 0.4 to about 3.5 mm. The implantable composite is configured to tit at or near a bone defect as an autograft extender to promote bone growth. Methods of using the implantable composite are also provided. 1. An implantable composite comprising a plurality of resorbable ceramic particles , the resorbable ceramic particles comprising carbonated hydroxyapatite and tricalcium phosphate in a ratio from about 5:95 to about 70:30 , wherein the resorbable ceramic particles are granules having an average diameter in the range from about 0.4 to about 3.5 mm.2. An implantable composite of claim 1 , wherein the implantable composite comprises a biodegradable polymer and the tricalcium phosphate is .beta. tricalcium phosphate.3. (canceled)4. An implantable composite of claim 1 , wherein a resorption rate of the implantable composite containing the carbonated hydroxyapatite increases from about 10% to about 40% when compared to a resorption rate of an implantable composite having resorbable ceramic particles comprising hydroxyapatite and .beta. tricalcium phosphate in a ratio from about 5:95 to about 70:30 but no carbonated hydroxyapatite.5. An implantable composite of claim 2 , wherein the biodegradable polymer comprises one or more poly(L-lactide-co-D claim 2 ,L-lactide) claim 2 , polyglyconate claim 2 , poly(acrylates) claim 2 , poly(anhydrides) claim 2 , poly(hydroxy acids) claim 2 , polyesters claim 2 , poly(orthoesters) claim 2 , poly(alkylene oxides) claim 2 , polycarbonates claim 2 , poly( ...

DENTAL CEMENT COMPOSITION

The present invention relates to dental cement composition that is more biocompatible and stimulates quicker healing of the damaged dental tissues. Specifically, the invention relates to dental cement composition comprising a combination of dental repair compounds consisting of nanoparticles of Tri-calcium Silicate (Ca3SiO5), Di-calcium Silicate (Ca2SiO4), Calcium Titanate (CaTiO3) and Hydroxyapatite (Ca10(PO4)6(OH)2). 1. A fast-setting dental cement composition comprising combination of dental repair compounds consisting of Tri-calcium Silicate (CaSiO) , Di-calcium Silicate (CaSiO) , Calcium Titanate (CaTiO) and hydroxyapatite (Ca(PO)(OH)) , wherein each of these compounds are in nanoparticulate form.2. A fast-setting dental cement composition according to claim 1 , wherein nanoparticles have a particle size of about 50 nm to about 500 nm.3. A fast-setting dental cement composition according to claim 1 , wherein nanoparticles have the particle surface area of about 1 to about 50 m/g.4. A fast-setting dental cement composition comprising combination of dental repair compounds consisting of about 35% to about 85% Tri-calcium Silicate (CaSiO) claim 1 , about 2% to about 8% Di-calcium Silicate (CaSiO) claim 1 , about 5% to about 15% Calcium Titanate (CaTiO) and about 10% to about 40% Hydroxyapatite (Ca(PO)(OH)) by weight based on the total weight of the dental repair compounds claim 1 , wherein each of these compounds are in nanoparticulate form.5. A fast-setting dental cement composition according to claim 4 , wherein nanoparticles have a particle size of about 50 nm to about 500 nm.6. A fast-setting dental cement composition according to claim 4 , wherein nanoparticles have the particle surface area of about 1 to about 50 m/g.7. A fast-setting dental cement composition comprising combination of dental repair compounds consisting of Tri-calcium Silicate (CaSiO) claim 4 , Di-calcium Silicate (CaSiO) claim 4 , Calcium Titanate (CaTiO) and hydroxyapatite (Ca(PO)(OH)) ...

HIGH-STRENGTH, TRANSLUCENT MG-HIGH QUARTZ MIXED CRYSTAL GLASS CERAMICS

The invention relates to the use of glass ceramics based on a high quartz mixed crystal system for dental purposes, which can be easily mechanically processed in an intermediate stage of crystallization and present high-strength, highly translucent and chemically stable glass ceramics following complete crystallization, wherein said glass or ceramics still have phosphorus and a transition metal compound, selected from titanium and zirconium or a mixture thereof. 1. Use of a magnesium oxide/aluminum oxide/silicon oxide glass or glass ceramics for application in dentistry , wherein said glass or glass ceramics have phosphorus and a transition metal compound , selected from the group consisting of titanium and zirconium or a mixture thereof.2. Use of a magnesium oxide/aluminum oxide/silicon oxide glass or glass ceramics according to claim 1 , wherein said magnesium oxide/aluminum oxide/silicon oxide glass or glass ceramics is a pure oxide glass.5. Use of a magnesium oxide/aluminum oxide/silicon oxide glass or glass ceramics according to claim 1 , wherein the primary crystalline phase is a magnesium high quartz mixed crystal.6. Use of a magnesium oxide/aluminum oxide/silicon oxide glass or glass ceramics according to claim 1 , comprising a crystalline phase consisting of lanthanum phosphate.7. Use according to by means of CAD/CAM and/or for chairside applications.8. Use according to claim 1 , wherein said glass or glass ceramics have additional transition metal cations and are used as dental coloring.9. Use according to claim 1 , wherein a fluorescence additive is added to said glass or glass ceramics to produce a fluorescence effect emulating nature claim 1 , preferably selected from cations of rare-earth elements claim 1 , particularly preferably from Er claim 1 , Eu claim 1 , Tb claim 1 , Pr claim 1 , and Gd.10. Use according to claim 1 , comprising:melting glass at temperatures between 1500 and 1800° C.,active or passive cooling of said glass to room temperature, ...

IMPLANT SURFACE COMPOSITION

An implant structure or parts thereof having a surface composition obtainable through an anodic oxidation process is disclosed. The surface composition comprising titanium oxide in the anatase crystalline phase and at least 90% of the pores have an orifice with a mean inside diagonal distance of less than 0.1 μm. It is also disclosed an implant system comprising said surface composition and a method of obtaining said surface. 1. An implant structure or parts thereof comprising:a surface composition comprising titanium oxide in the anatase crystalline phase, wherein said surface composition has a porous structure where at least 90% of pores have an orifice with a mean inside diagonal distance of less than 0.1 μm.2. The implant structure or parts thereof according to claim 1 , wherein the surface composition is obtainable through an anodic oxidation process.3. The implant structure or parts thereof according to claim 1 , in which said surface composition has a mean roughness value (Sa value) of below 0.3 μm.4. The implant structure or parts thereof according to claim 1 , in which at least 95% of the pores claim 1 , have an orifice with a mean inside diagonal distance of less than 0.2 μm.5. The implant structure or parts thereof according to claim 1 , in which said surface composition forms part of a tissue facing surface of a component of an implant system.6. The implant structure or parts thereof according to claim 1 , in which said surface composition forms part of a bore or other inner surface of a component of an implant system.7. The implant structure or parts thereof according to claim 1 , in which at least 35% by volume of said surface composition is formed by titanium oxide in the anatase phase.8. The implant structure or parts thereof according to claim 1 , in which a major content of said surface composition volume is formed by titanium oxide in the anatase phase.9. The implant structure or parts thereof according to claim 1 , in which said surface ...

DENTAL COMPOSITION

Dental compositions are disclosed. A dental composition can include a reaction produce of a reaction mixture comprising a first mixture and a second mixture. The first mixture can include a ceramic based biomaterial, and the second mixture can include mineral trioxide aggregate and a phosphoric acid monomer. 1. A dental composition , comprising: [ 'a ceramic based biomaterial, and', 'a first mixture comprising'}, mineral trioxide aggregate; and', 'a phosphoric acid monomer., 'a second mixture comprising'}], 'a reaction product of a reaction mixture comprising'}2. The dental composition of claim 1 , wherein the ceramic based biomaterial is chosen from calcium phosphates claim 1 , strontium phosphates claim 1 , calcium carbonates claim 1 , calcium sulfate claim 1 , and calcium hydroxide.3. The dental composition of claim 1 , wherein about 50 weight percent to about 80 weight percent of the first mixture comprises the ceramic based biomaterial claim 1 , the weight percent based on a total weight of the first mixture.4. The dental composition of claim 1 , wherein 60 weight percent of the first mixture comprises the ceramic based biomaterial claim 1 , the weight percent based on a total weight of the first mixture.5. The dental composition of claim 1 , wherein about 5 weight percent to about 50 weight percent of the second mixture comprises the mineral trioxide aggregate claim 1 , the weight percent based on a total weight of the second mixture.6. The dental composition of claim 1 , wherein the phosphoric acid monomer is chosen from at least one of 1-methacryloyloxydecane-10-phosphate claim 1 , 1-methacryloyloxyhexane-6-phosphate claim 1 , 1-methacryloylaminodecane-10-phosphate claim 1 , 1-acryloylaminohexane-6-phosphate claim 1 , 1 claim 1 ,3-dimethacryloyloxypropane-2-phosphate claim 1 , and 1 claim 1 ,3-dimethacryloylaminopropane-2-phosphate.7. The dental composition of claim 1 , wherein about 1 weight percent to about 15 weight percent of the second mixture comprises ...

DEPOSITION OF DISCRETE NANOPARTICLES ON AN IMPLANT SURFACE

A method of forming a nanocrystalline surface on an implant is disclosed. The method comprises the act of roughening at least a portion of the implant surface to form a roughened surface. The method further comprises the act of, without forming an alkoxide on the roughened surface, depositing nanocrystals on the roughened surface. The nanocrystals comprise a material having a property that promotes osseointegration. 1. A method of forming a nanocrystalline surface on an implant , the method comprising the acts of:roughening at least a portion of the implant surface to form a roughened surface;without forming an alkoxide on the roughened surface, depositing nanocrystals on the roughened surface, the nanocrystals comprising a material having a property that promotes osseointegration.2. The method of claim 1 , wherein the implant is made of a metal selected from the group consisting of tantalum claim 1 , cobalt claim 1 , chromium claim 1 , titanium claim 1 , stainless steel claim 1 , or alloys thereof.3. The method of claim 1 , wherein the metal comprises titanium.4. The method of claim 1 , wherein the implant is made of a material including ceramic.5. The method of claim 1 , wherein the implant is a dental implant.6. The method of claim 5 , wherein the portion of the implant surface is a threaded bottom portion for facilitating bonding with bone.7. The method of claim 1 , wherein the act of roughening the implant surface comprises:removing a native oxide layer from the implant surface; andacid etching the resulting surface.8. The method of claim 1 , wherein the act of roughening the implant surface creates irregularities claim 1 , the irregularities having peak-to-valley heights not greater than about 20 microns.9. The method of claim 1 , wherein the nanocrystals include hydroxyapatite claim 1 , the nanocrystals being on the order of about 20 nanometers to about 100 nanometers.10. The method of claim 9 , wherein the act of depositing the hydroxyapatite nanocrystals ...

Compositions and methods for adhesion to surfaces

The present disclosure features adhesive compositions and methods of use thereof related to the medical, veterinary, and dental fields.

TOOTH SURFACE REPAIRING MATERIAL

A method for repairing a tooth surface having scratches and hollow portions formed on a tooth enamel surface includes administering a tooth surface repairing material to a dental disease patient. The tooth surface repairing material contains a highly crystalline sintered fine calcium phosphate particle having an average particle diameter in the range of 20 to 100 nm. 1. A method for repairing a tooth surface having scratches and hollow portions formed on a tooth enamel surface by administering a tooth surface repairing material to a dental disease patient , wherein the tooth surface repairing material contains a highly crystalline sintered fine calcium phosphate particle having an average particle diameter in the range of 20 to 100 nm.2. The method for repairing tooth surface according to claim 1 , wherein the fine calcium phosphate particles are manufactured by a method which includes a mixing process to mix primary particles containing calcium phosphate and a fusion inhibitor and a sintering process to convert the primary particles included in the particle mixture into highly crystalline calcium phosphate particles by exposing the particle mixture to sintering temperature obtained by the mixing process.3. The method for repairing tooth surface according to claim 2 , wherein the fusion inhibitor used in the mixing process contains calcium ions.4. The method for repairing tooth surface according to claim 1 , wherein an abundance ratio (Ca/P) of the calcium atom with respect to the phosphorus atom on the surface of the fine calcium phosphate particles is 1.6 or more.5. The method for repairing tooth surface according to claim 1 , wherein at least some of the fine calcium phosphate particles are in the form of a particle.6. The method for repairing tooth surface according to claim 1 , wherein at least some of the fine calcium phosphate particles are fluoroapatite.7. The method for repairing tooth surface according to claim 1 , wherein the fine calcium phosphate ...

DENTAL COMPOSITION

The present invention relates to a dental composition comprising a specific radically polymerizable compound and a radical initiator system. Furthermore, the present invention relates to the specific radically polymerizable compound and its use in a dental composition. The specific radically polymerizable compound of the present invention has an allyl (meth)acrylamide group and a phosphoric acid ester group. 2. The dental composition according to claim 1 , comprising a compound of formula (I) wherein either Ror Ris a hydrogen atom claim 1 , or a salt thereof.3. The dental composition according to claim 1 , comprising a compound of formula (I) wherein both of Rand R claim 1 , which may be the same or different claim 1 , independently represent a group of formula (II) or (III) claim 1 , or a salt thereof.4. The dental composition according to claim 3 , comprising a compound of formula (I) wherein both of Rand R claim 3 , which may be the same or different claim 3 , represent a group of the following formula (II) claim 3 , or a salt thereof.5. The dental composition according to claim 3 , comprising a compound of formula (I) wherein both of Rand R claim 3 , which may be the same or different claim 3 , represent a group of the following formula (III) claim 3 , or a salt thereof.6. The dental composition according to claim 3 , wherein Rand Rare the same.7. The dental composition according to claim 1 , wherein the dynamic viscosity of the radically polymerizable compound of formula (I) is at most 10 Pa's at 23° C.8. The dental composition according to claim 1 , wherein Ris a hydrogen atom.9. The dental composition according to claim 1 , wherein Ris an allyl group.10. The dental composition according to claim 1 , wherein n is an integer of from 4 to 7.11. The dental composition according to claim 1 , wherein the radically polymerizable compound of formula (I) is contained in an amount of from 0.1 to 90 percent by weight based on the total weight of the composition.12. The ...

DENTAL COMPOSITION

Disclosed herein is a dental composition having a polymerization initiator system with an aromatic tertiary phosphine compound. Further disclosed is the use of the aromatic tertiary phospine compound for the preparation of a photocurable dental compositions. 1. A dental composition comprising(a) one or more compounds having at least one polymerizable double bond; (b1) a sensitizer; and', [{'br': None, 'Z—R\u2003\u2003 (I)'}, 'wherein', [{'br': None, 'sup': '1', 'R(Ar)P—\u2003\u2003 (II)'}, 'wherein', {'sup': '1', 'Rrepresents a substituted or unsubstituted hydrocarbyl group;'}, 'Ar represents a substituted or unsubstituted aryl or heteroaryl group;, 'Z is a group of the following formula (II)'}, {'sup': 2', '3', '2', '3, 'sub': '1-6', 'R is an aryl group, which may be substituted by one or more groups selected from a hydroxyl group, an amino group, a —NRRgroup (wherein Rand R, which may be the same or different, are selected from Calkyl groups), a carboxyl group, and a group having a polymerizable double bond;'}], '(b2) an aromatic tertiary phosphine compound of the following formula (I), {'sup': 1', '2', '3', '2', '3', '2', '3', '2', '3, 'sub': 1-6', '1-6, 'wherein the group Rand Ar may be substituted by one or more groups selected from a hydroxyl group, an oxo group, a —NRRgroup (wherein Rand R, which may be the same or different, are selected from a hydrogen atom and Calkyl groups), a carboxyl group, and a group having a polymerizable double bond, and L may be substituted by one or more groups selected from a hydroxyl group, an oxo group, a —NRRgroup (wherein Rand R, which may be the same or different, are selected from a hydrogen atom and Calkyl groups), a carboxyl group, and a group having a polymerizable double bond.'}], '(b) a polymerization initiator system comprising'}2. The dental composition according to claim 1 , wherein the polymerization initiator system further comprises(b3) an electron-donor.3. The dental composition according to claim 1 , wherein ...

Formulations and kit for biometric deposition of apatite on teeth

The invention proposes a kit and formulations for biomimetic deposition of apatite on teeth from a partially elastic shaped body comprising an envelope, whereby the shaped body a) comprises at least one mineralization matrix containing a gel that comprises water-soluble phosphates or phosphates that can be hydrolysed to form water-soluble phosphate ions and has a pH value of 2 to 8, optionally fluorides, and b) the at least one or a second mineralization matrix comprises a second gel having a pH value of 3.5 to 14 comprising calcium ions or compounds releasing calcium ions. Moreover, the method for producing the formulation and the use thereof for the deposition of apatite, in particular of needle-shaped fluorapatite crystallites, is claimed. Using the formulations according to the invention, it is feasible to deposit more than or equal to 1 μm apatite, in particular fluorapatite, on tooth surfaces in order to seal or brighten porous tooth surfaces. 1. A formulation comprising at least one partially elastic shaped body , said body comprising at least one mineralization matrix containing at least one gel , whereby the shaped body comprises , at least in part , in at least one plane a reduced solubility with respect to aqueous media as compared to the mineralization matrix , whereby the plane acts as membrane , anda) the at least one mineralization matrix comprises a gel containing water-soluble phosphates or hydrolysable phosphates that form water-soluble phosphate ions and has a pH value of 2 to 8, andb) the at least one or a second mineralization matrix comprises a second gel comprising calcium ions or compounds releasing calcium ions and has a pH value of 3.5 to 14.2. Formulation according to claim 1 ,wherein the at least one mineralization matrix is present in a first shaped body and the second mineralization matrix is present in a second shaped body.3. Formulation according to whereina) the at least one mineralization matrix comprises a gel comprising(i) water- ...

DENTAL COMPOSITIONS WITH CALCIUM PHOSPHORUS RELEASING GLASS

The present application provides a glass composition comprising 10-50% by weight CaO, at least 15% and less than 50% by weight PO, less than 3% by weight AlO, less than 10% by weight LiO, NaO, and KO combined, and 0-60% by weight of SrO, MgO, BaO, ZnO, or combinations thereof; dental compositions comprising the glass composition, and methods of making and using such dental compositions. 1. A glass composition comprising 10-50% by weight CaO , at least 15% and less than 50% by weight PO , less than 3% by weight AlO , less than 10% by weight LiO , NaO , and KO combined , and 0-60% by weight of SrO , MgO , BaO , ZnO , or combinations thereof.2. The glass composition of claim 1 , wherein the glass is amorphous.3. The glass composition of claim 1 , wherein the glass is at least partially crystalline.4. The glass composition of claim 1 , wherein the glass is in a finely divided form of particles claim 1 , fibers claim 1 , or platelets.65. The glass composition of claim claim 1 , wherein the particles claim 1 , fibers claim 1 , or platelets are surface-treated.7. The glass composition of claim 6 , wherein the surface treatment comprises a silane.8. The glass composition of claim 1 , further comprising fluoride in an amount less than 25% by weight of the glass composition.9. The glass composition of claim 1 , further comprising BOin an amount less than 30% by weight of the glass composition.10. The glass composition of claim 1 , further comprising SiOin an amount less than 20% by weight of the glass composition.11. The glass composition of claim 10 , wherein the amount is less than 1% by weight of the glass composition.12. The glass composition of claim 1 , further comprising up to 40% by weight of a rare earth oxide.13. The glass composition of claim 1 , further comprising ZrOin an amount less than 15% by weight of the glass composition.14. A dental composition comprising the glass composition of .15. The dental composition of claim 14 , wherein the dental composition ...

BIOMATERIAL COATED WITH HAp/Col COMPOSITE

A biomaterial in which the surface of a metal base is coated with a coating agent containing a composite of hydroxyapatite and collagen in which the c-axis of hydroxyapatite in the composite is oriented along collagen fibers is used. 1. A biomaterial in which the surface of a metal base is coated with a coating agent containing a composite of hydroxyapatite and collagen , wherein the c-axis of hydroxyapatite in the composite is oriented along collagen fibers.2. The biomaterial of claim 1 , wherein the ratio by weight of hydroxyapatite and collagen in the composite is 3:2 to 9:1.3. The biomaterial of claim 1 , wherein the biomaterial is an implant material or an onplant material for oral surgery claim 1 , orthopedic surgery claim 1 , brain surgery claim 1 , dentistry claim 1 , ophthalmology or otolaryngology.4. A coating agent for promoting osteosynthesis for a biomaterial which contains a composite of hydroxyapatite and collagen in which the c-axis of hydroxyapatite is oriented along collagen fibers.5. A method for producing a biomaterial which contains a step of coating the surface of a metal base with the coating agent for promoting osteosynthesis of .6. The biomaterial of claim 2 , wherein the biomaterial is an implant material or an onplant material for oral surgery claim 2 , orthopedic surgery claim 2 , brain surgery claim 2 , dentistry claim 2 , ophthalmology or otolaryngology. This invention relates to a biomaterial which is implanted in a living body.As described in PTL 1 for example, for biomaterials such as an artificial tooth root implant and an artificial bone implant, titanium or an alloy material thereof with excellent biocompatibility is used as the constituting metal material, and it is known that the biocompatibility becomes excellent by coating the surface of the metal base with hydroxyapatite.Here, it is known that bone of vertebrates is a composite of an inorganic substance, hydroxyapatite (HAp), and an organic substance, collagen, that HAp forms ...

DENTAL MATERIAL

The present invention provides a dental material containing nanofibers and a biocompatible resin. In one embodiment, this dental material is an implant material, prosthetic material, or denture material and has mechanical strength suited to the site of use in the body as well as exceptional dimensional stability and exceptional wear resistance. Because the compressive strength can be controlled, excessive burden on the teeth when occlusal force is applied is suppressed when the dental material is used in the oral cavity. In addition, secondary caries can be suppressed because the antimicrobial properties make plaque less likely to adhere to the teeth and make the teeth less likely to be affected by bacteria. This dental material can be used without modification as a desired dental material, and can also be made into a desired dental material by molding as needed. In addition, materials produced from these nanofibers and this resin can also be used in applications other than dental materials. 1. A dental material comprising a nanofiber and a biocompatible resin , wherein the biocompatible resin comprises 4-methacryloxyethyl trimellitic anhydride (4-META).2. The dental material of claim 1 , wherein the nanofiber is a cellulose nanofiber.3. The dental material of claim 2 , wherein the nanofiber further comprises one or more of a chitosan nanofiber and a chitin nanofiber.4. The dental material of claim 1 , wherein the dental material comprises an antimicrobial substance.5. The dental material of claim 1 , wherein the dental material is an implant material claim 1 , a prosthetic material claim 1 , a denture material claim 1 , a filler claim 1 , a denture plate material claim 1 , a mold repairing material claim 1 , or an impression material.6. The dental material of claim 5 , wherein the dental material is an implant material claim 5 , a prosthetic material claim 5 , or a denture material with a compressive strength within a range of 300 MPa to 400 MPa.7. The dental ...

PHOSPHOCALCIC CEMENT COMPOSITION COMPRISING BLOOD

A bone cement paste containing a powder component comprising α-tricalcium phosphate (α-TCP) particles having an average size greater than or equal to 9 μm, and a liquid component comprising blood is disclosed. A method for preparation of the phosphocalcic cement composition is also disclosed. 1. A bone cement paste containing a powder component comprising α-tricalcium phosphate (α-TCP) particles having an average size greater than or equal to 9 μm , and a liquid component comprising blood.2. The bone cement paste of claim 1 , wherein the liquid component is blood.3. The bone cement paste of claim 1 , wherein the powder component further comprises at least one calcium phosphate compound other than α-TCP.4. The bone cement paste of claim 3 , wherein the calcium phosphate compound is selected from the group consisting of hydroxyapatite (HA) claim 3 , amorphous calcium phosphate (ACP) claim 3 , monocalcium phosphate anhydrous (MCPA) claim 3 , monocalcium phosphate monohydrate (MCPM) claim 3 , dicalcium phosphate dihydrate (DCPD) claim 3 , dicalcium phosphate anhydrous (DCPA) claim 3 , precipitated or calcium-deficient apatite (CDA) claim 3 , β-tricalcium phosphate (β-TCP) claim 3 , tetracalcium phosphate (TTCP) claim 3 , and mixtures thereof.5. The bone cement paste of any one of claim 1 , wherein the powder component comprises:α-tricalcium phosphate (α-TCP) particles having an average size greater than or equal to 9 μm, andat least one calcium phosphate compound selected from the group consisting of: MCPM, DCPD, CDA, and mixtures thereof.6. The bone cement paste of claim 1 , wherein the powder component comprises at least 70% by weight of α-tricalcium phosphate (α-TCP) particles having an average size greater than or equal to 9 μm claim 1 , in relation to the total weight of said powder component.7. The bone cement paste of claim 1 , wherein the powder component comprises:α-tricalcium phosphate (α-TCP) particles having an average size greater than or equal to 9 μmMCPM, ...

DENTAL PROSTHESIS AND COMPONENT THEREOF

This invention provides a measure that makes it possible to prevent more effectively, in comparison with the prior art, the invasion of germs from the gap between a dental prosthesis and the gingiva when the dental prosthesis is used in an oral cavity as well as the infection and inflammation associated therewith. 1. A dental prosthesis or a component thereof , whereinthe dental prosthesis or the component thereof comprises hydroxyapatite fine particles on a surface of the dental prosthesis or the component thereof,the hydroxyapatite fine particles are sintered bodies, andthe hydroxyapatite fine particles have a mean particle size of 10 to 1,000 nm.2. The dental prosthesis or the component thereof according to claim 1 , wherein the dental prosthesis is an implant that is an artificial dental root to be embedded in a bone in an oral cavity claim 1 , and the component is an abutment used for the implant. The present invention relates to a dental prosthesis used in an oral cavity and a component thereof.As shown in , an implant (implant kit) is composed of an upper structure - (dental crown part: implant denture) and an implant body - {dental root part: fixture (artificial dental root)}. Here, an abutment - is a part that connects the upper structure - and the implant body - via a screw -.When a long period elapses after the implant was embedded, a gap is formed between the abutment (dental material) and the gingiva, and germs invade through said gap, which may cause infection and inflammation. Accordingly, various methods have been proposed to solve this problem.First, Patent Literature 1 proposes a technical solution of imparting antibacterial properties to an artificial dental root by coating a gingival abutting surface of the artificial dental root with a bioinert component {CaMgSiO(diopside) crystal}. In addition, Patent Literature 2 proposes a technical solution of applying an antimicrobial coating to an abutment for forming a surface layer containing gallium ...

Stabilized Calcium Phosphate

A method of forming a stabilized calcium phosphate moiety for use in dental or biomedical applications includes providing a solution or dispersion including a calcium salt and reacting an organic phosphate having a polymerizable methacrylate or vinyl group with the solution or dispersion in order to form the calcium phosphate moiety having at least one pendant polymerizable group and at least one organic functional group, which may be the same group. A polymerizable composite system having a stabilized calcium phosphate formed according to the method is also provided. 1. A polymerizable composite system for use in dental or biomedical applications , the system comprising:stabilized calcium phosphate formed by providing a solution or dispersion including a calcium salt dissolved or dispersed in water or a suitable solvent and reacting bis[2-(methacryloyloxy)ethyl] phosphate with the solution or dispersion in order to form a calcium phosphate moiety having at least one pendant polymerizable group and at least one organic functional group; andone or more monomers selected from the group consisting of acidic monomers, hydrophilic monomers, hydrophobic monomers, and combinations thereof.2. The polymerizable composite system of claim 1 , wherein the one or more monomers includes urethane dimethacrylate claim 1 , bis[2-(methacryloyloxy)ethyl] phosphate claim 1 , 1 claim 1 ,6 hexamethylene dimethacrylate claim 1 , trimethylol propane triacrylate claim 1 , hydroxyethyl methacrylate claim 1 , polyethylene glycol methacrylate claim 1 , triethylene glycol dimethacrylate claim 1 , polyethylene glycol dimethacrylate claim 1 , polylactic acid methacrylate claim 1 , polycaprolactone methacrylate claim 1 , bisphenol A glycidyl methacrylate claim 1 , bisphenol A glycidyl diacrylate claim 1 , bisphenol A ethoxylate dimethacrylate claim 1 , bisphenol A dimethacrylate claim 1 , bisphenol A diglycidyl ether or a combination thereof.3. The polymerizable composite system of claim 1 , ...

POLYARYLETHERKETONE DENTAL BLOCK FOR CAD/CAM MILLING

A method of making a prosthetic dental item comprises selecting a block having a square or rectangular cross-section along is extent, wherein said block comprises polyetheretherketone and, optionally, an apatite, wherein said polymeric material has a crystallinity of at least 25%. The method comprises machining the block in dependence upon data collated using digital technology. Since the crystallinity of the material selected is high, a post-machining step whereby crystallinity is increased can be avoided, and dental items of high precision can be formed. 2. A method according to claim 1 , wherein the crystallinity of said polymeric material is greater than 20% claim 1 , preferably greater than 30%.3. A method according to claim 1 , wherein said block has a volume of at least 900 mmand less than 65 claim 1 ,000 mm; and/or said block has a minimum side length of 7 mm and a maximum of 75 mm; and/or said block has a cross-section with an area in the range 50 mmto 1000 mm(preferably 50 to 200 mm); and/or said block has a length in the range 10 mm to 80 mm (preferably 15 mm to 20 mm).4. A method according to claim 1 , wherein said polymeric material consists essentially of a repeat unit of formula I claim 1 , wherein t1=1 claim 1 , v1=0 and w1=0.5. A method according to claim 1 , wherein said polymeric material has a melt viscosity in the range 0.09 to 0.5 KNsm.6. A method according to claim 1 , wherein said composition comprises at least 80 wt % or at least 94 wt % of said polymeric material.7. A method according to claim 1 , wherein said block comprises a composition comprising said polymeric material (especially a polymeric material consisting essentially of repeat units of formula I wherein t1=1 claim 1 , w1=0 and v1=0) and an apatite claim 1 , wherein the ratio of the wt % of said polymeric material divided by the wt % of said apatite is in the range 1 to 9.8. A method according to claim 7 , wherein the ratio of the wt % of said polymeric material divided by the wt ...

Dental glass and dental composition

A dental glass includes: phosphorus; sodium and/or potassium; and calcium, wherein the dental glass contains, in terms of oxide, phosphorus (P 2 O 5 ) by greater than or equal to 40% by mass and less than or equal to 70% by mass, sodium and/or potassium (Na 2 O, K 2 O) by greater than or equal to 20% by mass and less than or equal to 40% by mass, and calcium (CaO) by greater than or equal to 1% by mass and less than or equal to 20% by mass, and wherein the dental glass does not substantially contain silicon and aluminum.

COMPOSITE PART FOR ENDOSSEOUS IMPLANTATION AND METHOD FOR MANUFACTURING SAME

A part adapted for in vivo endosseous implantation made up of a material comprising a thermoplastic organic binder and a fiber charge. The fibers located in a surface layer of the part are mostly delaminated from the binder over all or part of their length. Also, a method for manufacturing such a part. 117-. (canceled)18. A part adapted for in vivo endosseous implantation comprising a material comprising:a thermoplastic organic binder, anda fiber charge;wherein fibers located in a surface layer of said part are mostly delaminated from the binder over all or part of their length.19. The part according to claim 18 , wherein the fiber charge comprises nanofibers or nanotubes.20. The part according to claim 18 , wherein the fiber charge comprises microfibers.21. The part according to claim 18 , wherein the binder comprises polyetheretherketone.22. The part according to claim 18 , wherein the fibers are made of a polymer of a family of aromatic polyamides.23. The part according to claim 22 , wherein the fibers are made of poly(amide-imide).24. The part according to claim 18 , comprising fibers made of calcium silicate (CaSiO).25. The part according to claim 18 , wherein the thickness of the surface layer is greater than or equal to 2000 nanometers.26. The part according to claim 18 , wherein the material further comprises a charge of components made from calcium and phosphate.270. The part according to claim 26 , wherein the charge of calcium-based components is made up of tricalcium phosphate Ca(PO)with a hexagonal structure.28. The part according to claim 26 , wherein the material further comprises a zeolite charge.29. A method for manufacturing the part according to claim 18 , comprising the steps of:mixing a thermoplastic polymer and a fiber charge by extrusion and granulation to provide a granulate;molding the part by injection in a mold comprising a cavity with a shape configured for the granulate to provide a blank; andsubmitting the blank to ultrasonic pickling ...

CURABLE CALCIUM PHOSPHATE COMPOSITION FOR BIOLOGICAL HARD TISSUE REPAIR, BONE REPAIR MATERIAL, AND VARIOUS DENTAL MATERIALS

The present invention provides a curable calcium phosphate composition for biological hard tissue repair that yields a cured product excellent in durability in a wet environment such as in a body or an oral cavity. The present invention relates to a curable calcium phosphate composition for biological hard tissue repair, including tetracalcium phosphate particles (A), calcium hydrogen phosphate particles (B), calcium carbonate particles (C), and water (D), the curable calcium phosphate composition including 5 to 75 parts by weight of the tetracalcium phosphate particles (A), 10 to 70 parts by weight of the calcium hydrogen phosphate particles (B), and 2 to 50 parts by weight of the calcium carbonate particles (C) per 100 parts by weight of the total of the tetracalcium phosphate particles (A), the calcium hydrogen phosphate particles (B), and the calcium carbonate particles (C). 1. A curable calcium phosphate composition for biological hard tissue repair , comprising tetracalcium phosphate particles (A) , calcium hydrogen phosphate particles (B) , calcium carbonate particles (C) , and water (D) ,the curable calcium phosphate composition comprising 5 to 75 parts by weight of the tetracalcium phosphate particles (A), 10 to 70 parts by weight of the calcium hydrogen phosphate particles (B), and 2 to 50 parts by weight of the calcium carbonate particles (C) per 100 parts by weight of the total of the tetracalcium phosphate particles (A), the calcium hydrogen phosphate particles (B), and the calcium carbonate particles (C).2. The curable calcium phosphate composition according to claim 1 , further comprising 0.5 to 15 parts by weight of an alkali metal phosphate (E) per 100 parts by weight of the total of the tetracalcium phosphate particles (A) claim 1 , the calcium hydrogen phosphate particles (B) claim 1 , and the calcium carbonate particles (C).3. The curable calcium phosphate composition according to claim 2 , wherein the alkali metal phosphate (E) is at least one ...

FORMULATIONS AND MATERIALS WITH CATIONIC POLYMERS

This invention provides fluid formulations and materials produced therefrom for repairing dental and bone defects, processes for the production of the fluid formulations and materials, and to uses of these formulations and materials. In particular, the invention provides the use cationic polymers such as polylysine in these formulations and materials, and the advantageous properties derived therefrom which include mechanical and antibacterial properties. 1. A process for production of a material comprising the steps of:i) providing a fluid formulation comprising (1) at least one compound capable of polymerisation and/or cross-linking, (2) optionally a filler, and (3) a cationic polymer;ii) optionally introducing said fluid formulation into a site of use; andiii) polymerising and/or cross-linking said compound, to form a solid polymer matrix comprising the cationic polymer.2. The process of claim 1 , wherein the cationic polymer comprises a monomeric subunit having a nitrogen-containing group.3. The process of claim 1 , wherein the cationic polymer is selected from the group consisting of polylysine claim 1 , polyarginine claim 1 , polyhistamine claim 1 , chitosan claim 1 , a polyamide claim 1 , polyacrylamide claim 1 , polyisopropylacrylamide claim 1 , polyethylenimine and pre-polymerised methacryates.4. (canceled)5. The process of claim 1 , wherein the at least one compound capable of polymerisation and/or cross-linking comprises a polymerisable methacrylate moiety UDMA claim 1 , PPGDMA claim 1 , BISGMA claim 1 , methylmethacrylate claim 1 , acrylic acid claim 1 , HEMA claim 1 , TEGDMA or polyacid.6. The process of claim 1 , wherein the formulation further comprises one or more of the following additives: a polymerisation initiator; diluent monomers; hydroxyquinone; or an active agent.7. The process of claim 1 , wherein the fluid formulation comprises the filler claim 1 , and the filler comprises an active agent selected from one or more of an antibacterial agent ...

TOOTH-SURFACE-MEMBRANE-FORMING POWDER CONTAINING SINTERED APATITE

In order to provide a film-forming powder using hydroxyapatite which is a main component of teeth, or hydroxyapatite in which a color tone adjuster is blended, the powder being used in a jet-device for forming a film on a surface of a tooth by spraying the powder on the tooth, and being suitable for forming a film having a high hardness and extremely low solubility in acid in a short period of time, and suitable for forming a film of a powder conforming to the color tone of a tooth in a short period of time; a hydroxyapatite powder calcined in an inert gas atmosphere at 600 to 1350° C., a powder obtained by applying to the hydroxyapatite powder calcined at 600 to 1350° C. plasma irradiation, or plasma irradiation and mechanical energy, and additionally a film-forming powders obtained by blending color tone adjusters into these hydroxyapatite powders are produced. 1. A film-forming powder for forming a film on a surface of a tooth for use in a jet-device for a tooth , the powder having a mean particle size of 0.5 to 30 μm , wherein the film-forming powder is produced by calcining an apatite represented by Ca.M(ZO)Y(wherein X represents 0 to 10; M represents a metal or hydrogen; ZOrepresents PO , CO , CrO , AsO , VO , SiO , SOor GeO; and Y represents a hydroxyl group , a halogen element or a carbonate group) at 600 to 1350° C. followed by plasma irradiation.2. The film-forming powder according to claim 1 , wherein the apatite is hydroxyapatite.3. The film-forming powder according to claim 1 , wherein the film-forming powder is calcined in an inert gas atmosphere at 600 to 1350° C.4. The film-forming powder according to claim 3 , wherein the inert gas is argon gas or nitrogen gas.5. The film-forming powder according to claim 1 , wherein a color tone adjuster for adjusting a color tone of a tooth crown is further blended in the film-forming powder.6. The film-forming powder according to claim 5 , wherein the color tone adjuster of a tooth crown is at least one selected ...

Powder mixture, use of the powder mixture, and a powder jet device

The present invention relates to a powder mixture, in particular for the remineralization of teeth, a powder jet device, in particular for application in the field of dentistry, a use of the powder mixture for producing a means for the remineralization of teeth and to a method for the remineralization of teeth, and a use of a powder mixture in a dental apparatus. The powder mixture comprises a deposition powder which is designed to adhere to tooth surfaces.

RECHARGEABLE CALCIUM PHOSPHATE-CONTAINING DENTAL MATERIALS

The present invention provides rechargeable dental materials that can be widely applied in a variety of dental applications. The rechargeable dental materials of the invention may be included in dental primers, dental adhesives, dental resins, dental composites, dental bonding systems and the like, as well as dental cements, dental sealants, dental bases and dental liners, each of which is rechargeable with calcium and phosphate ions. The present invention also provides for a method of recharging the rechargeable dental material with calcium and phosphate ions. 1. A rechargeable dental material comprising (i) two or more rechargeable monomers and (ii) nanoparticles of amorphous calcium phosphate (NACP) ,wherein the combined amount of the two or more rechargeable monomers is about 10% to about 90% of the mass of the material, andwherein the NACP is present in an amount of about 20% to about 40% of the mass of the material.2. A rechargeable dental adhesive comprising the rechargeable dental material according to and one or more curing agents claim 1 ,wherein the combined amount of the one or more curing agents is about 0.05% to about 5% of the mass of the adhesive, andwherein the NACP is present in an amount of about 20% to about 30% by mass of the material.3. A rechargeable orthodontic cement comprising the rechargeable dental material according to and one or more curing agents claim 1 ,wherein the combined amount of the one or more curing agents is about 0.05% to about 5% of the mass of the cement,wherein the NACP is present in an amount of about 30% to about 40% by mass of the material.4. A rechargeable dental composite comprising the rechargeable dental material according to and one or more fillers selected from the group consisting of glass fillers claim 1 , ceramic fillers claim 1 , and polymer-based fillers claim 1 ,wherein the combined amount of the one or more fillers is about 30% to about 70% of the mass of the composite.5. The rechargeable dental material ...

ONE-COMPONENT-TYPE DENTINAL TUBULE SEALANT

A dentinal tubule sealant including apatite particles (A) having an average particle diameter of 500 nm or less, a filler (B) having an average particle diameter of 1 to 10 μm, and a dispersant (C), wherein the weight ratio (A/B) of the apatite particles (A) to the filler (B) is 0.05 to 15, the dentinal tubule sealant contains 15 to 95 parts by weight of the dispersant (C) relative to 100 parts by weight in total of the apatite particles (A) and the filler (B), and the total amount of the apatite particles (A), the filler (B), and the dispersant (C) is 85 parts by weight or more relative to 100 parts by weight of the dentinal tubule sealant. There is thereby provided a dentinal tubule sealant excelling in dentinal tubule sealability immediately after treatment, durability of dentinal tubule sealing, ease of operation, and storage stability. 2: The dentinal tubule sealant according to claim 1 , wherein the filler (B) is an inorganic filler (b) claim 1 , an organic filler (b′) claim 1 , or both.3: The dentinal tubule sealant according to claim 1 , wherein the filler (B) is at least one inorganic filler (b) selected from the group consisting of basic calcium phosphate particles (b1) claim 1 , poorly-soluble calcium phosphate particles (b2) claim 1 , a phosphorus-free calcium compound (b3) claim 1 , and an inorganic filler (b4) other than (b1) to (b3).4: The dentinal tubule sealant according to claim 1 , wherein the filler (B) is an inorganic filler (b) selected from the group consisting of a mixture of basic calcium phosphate particles (b1) and poorly-soluble calcium phosphate particles (b2) and a mixture of poorly-soluble calcium phosphate particles (b2) and a phosphorus-free calcium compound (b3) claim 1 , such that a Ca/P ratio of the sum of (b1) and (b2) or the sum of (b2) and (b3) is 1.2 to 2.0.5: The dentinal tubule sealant according to claim 1 , wherein the filler (B) is an inorganic filler (b) comprising a mixture of basic calcium phosphate particles (b1) claim ...

LITHIUM DISILICATE-APATITE GLASS CERAMIC WITH TRANSITION METAL OXIDE

Lithium disilicate-apatite glass ceramics comprising transition metal oxide are described which are characterized by a high chemical stability, and the translucence of which can be adjusted as desired, and which can therefore be used in particular as restoration material in dentistry. 1. Lithium disilicate-apatite glass ceramic , which comprises lithium disilicate as main crystal phase and apatite as further crystal phase , and which comprises divalent oxide selected from the group of CaO , SrO and mixtures thereof and transition metal oxide selected from the group of oxides of transition metals with an atomic number from 39 to 79 and mixtures thereof , wherein the molar ratio of divalent oxide to transition metal oxide is in the range of from 1.0 to 20.0.2. Glass ceramic according to claim 1 , which comprises 52.0 to 75.0 wt.-% SiO.3. Glass ceramic according to claim 1 , which comprises 10.0 to 20.0 wt.-% LiO.4. Glass ceramic according to claim 1 , which comprises 4.0 to 8.0 wt.-% PO.5. Glass ceramic according to claim 1 , which comprises 2.0 to 9.0 wt.-% divalent oxide.6. Glass ceramic according to claim 1 , which comprises 2.5 to 8.5 wt.-% CaO.7. Glass ceramic according to claim 1 , which comprises 1.0 to 6.5 wt.-% SrO.8. Glass ceramic according to claim 1 , which comprises 0.1 to 1.5 wt.-% F.9. Glass ceramic according to claim 1 , which comprises 0 to 4.0 wt.-% AlO.10. Glass ceramic according to claim 1 , which comprises 0.5 to 8.5 wt.-% transition metal oxide.11. Glass ceramic according to claim 1 , in which the transition metal oxide is selected from the group of LaO claim 1 , YO claim 1 , ErO claim 1 , ZrO claim 1 , CeO claim 1 , TbO claim 1 , VO claim 1 , TaO claim 1 , NbOand mixtures thereof.12. Glass ceramic according to claim 1 , in which the transition metal oxide is present{'sub': 2', '3, 'according to the formula MeOin an amount of from 0 to 5.0 wt.-%.'}{'sub': '2', 'according to the formula MeOin an amount of from 0 to 6.5 wt.-%.'}{'sub': 4', '7, ' ...

CHITOSAN-CALCIUM PHOSPHATE COMPOSITE AS ODONTOINDUCTIVE DENTAL FILLINGS AND METHODS OF MAKING AND USING

A dental or bone material comprising a polysaccharide, diepoxide and calcium phosphate. The polysaccharide can be a chitosan, and the polysaccharide is modified to be soluble. The combination of the polysaccharide and diepoxide form a gel, which can be cured to form the implant. The curing does not require equipment, but instead the material is self-curing. Methods of making and using the material are also disclosed. 1. A method of forming a hydrogel , comprising:providing a modified polysaccharide, wherein the modified polysaccharide comprises a chitosan modified to form a soluble chitosan; andcrosslinking the modified polysaccharide with a diepoxide to form the hydrogel.2. The method of claim 1 , further comprising mixing between about 0 wt. % and about 40 wt. % total of at least one additive with the modified polysaccharide.3. The method of claim 1 , wherein the diepoxide is 1 claim 1 ,4 butanediol diglycidyl.4. The method of claim 1 , wherein the soluble chitosan comprises a carboxymethyl group.5. The method of claim 1 , wherein the additive is at least one of a calcium phosphate claim 1 , growth factors claim 1 , chemokines claim 1 , SDF-1a claim 1 , and a bovine serum albumin.6. The method of claim 5 , wherein additive comprises the calcium phosphate and the calcium phosphate is at least one of a hydroxyapatite claim 5 , a dicalcium phosphate dihydrate claim 5 , a tetraethylene glycol diacrylate modified hydroxyapatite or a tetraethylene glycol diacrylate modified dicalcium phosphate.7. The method of claim 6 , wherein the calcium phosphate is the tetraethylene glycol diacrylate modified hydroxyapatite or the tetraethylene glycol diacrylate modified dicalcium phosphate claim 6 , and wherein the tetraethylene glycol diacrylate is in excess.8. A method to form an implantable material claim 6 , comprising:providing between about 2 wt. % and about 15 wt. % of a modified polysaccharide, wherein the modified polysaccharide comprises a polysaccharide modified with a ...

CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME

Disclosed are cement products, methods of forming cement using the cement product, and methods of using the cement product in orthopedic and dental applications. Generally, the disclosed cement product includes a first component and a second component. The first component comprises a polymerizable resin comprising ethylenic unsaturated double bond, a suitable glycidyl group and/or a suitable isocyanate group. The second component includes a compound comprising more than one type of amine selected from the group consisting of primary amine, secondary amines, tertiary amines and quaternary amines. Alternatively, the second component includes a compound comprising a suitable mercapto (SH—) group, a hindered amine or a dimethylthiotoluenediamine (DMTDA). Optionally, the cement product includes a filler and/or a bioactive component to promote bone formation. 1. A method of forming a cement product , the method comprising: the first component comprises a polymerizable resin that comprises two or more acrylate groups; and', 'the second component comprises a compound selected from the group consisting of (i) a compound that includes more than one type of amine selected from the group consisting of a primary amine, a secondary amine, a tertiary amine, and a quaternary amine, (ii) a compound that includes a mercapto group, (iii) a compound that includes a hindered amine, (iv) a dimethylthiotoluenediamine (DMTDA) compound, and (v) a combination of two or more compounds of (i)-(iv), and', 'wherein the first component, the second component, or both the first and second components comprise a bioceramic filler;, '(i) mixing a first component and a second component, wherein'}(ii) allowing the first component and second component to react with each other in a polymerization reaction at room temperature to produce an orthopedic or dental cement having a compressive strength of about 20 MPa to about 250 MPa, and(iii) allowing the polymerization reaction mixture to set at about 37° C., ...

Stabilized Calcium Phosphate and Methods of Forming Same

A method of forming a stabilized calcium phosphate moiety for use in dental or biomedical applications includes providing a solution or dispersion including a calcium salt and reacting an organic phosphate having a polymerizable methacrylate or vinyl group with the solution or dispersion in order to form the calcium phosphate moiety having at least one pendant polymerizable group and at least one organic functional group, which may be the same group. A polymerizable composite system having a stabilized calcium phosphate formed according to the method is also provided. 1. A method of forming a stabilized calcium phosphate for use in dental or biomedical applications , the method comprising:providing a solution or dispersion including a calcium salt; andreacting an organic phosphate having a polymerizable methacrylate or vinyl group with the solution or dispersion in order to form a calcium phosphate moiety having at least one pendant polymerizable group and at least one organic functional group.2. The method of claim 1 , wherein the at least one pendant polymerizable group and the at least one organic functional group are the same group.3. The method of claim 1 , wherein the calcium salt includes calcium chloride claim 1 , calcium hydroxide claim 1 , calcium nitrate claim 1 , or a combination thereof.4. The method of claim 1 , wherein the organic phosphate having the polymerizable methacrylate or vinyl group includes bis[2-(methacryloyloxy)ethyl] phosphate claim 1 , methacryloxy ethyl phosphate claim 1 , glycerol dimethacrylate phosphate claim 1 , glycerol monomethacrylate phosphate claim 1 , triethyleneglycol methacrylate phosphate claim 1 , methacryloyloxy propyl phosphate claim 1 , methacryloyloxy hexyl phosphate claim 1 , vinyl phosphonic acid claim 1 , allyl phosphonic acid claim 1 , polyethylene glycol methcrylate phosphate claim 1 , methacrylated aminomethyl phosphonic acid claim 1 , methacrylate esters of glycerol phosphate claim 1 , polycaprolactone ...

TOOTH-SURFACE-MEMBRANE-FORMING POWDER CONTAINING SINTERED APATITE

In order to provide a film-forming powder using hydroxyapatite which is a main component of teeth, or hydroxyapatite in which a color tone adjuster is blended, the powder being used in a jet-device for forming a film on a surface of a tooth by spraying the powder on the tooth, and being suitable for forming a film having a high hardness and extremely low solubility in acid in a short period of time, and suitable for forming a film of a powder conforming to the color tone of a tooth in a short period of time; a hydroxyapatite powder calcined in an inert gas atmosphere at 600 to 1350° C., a powder obtained by applying to the hydroxyapatite powder calcined at 600 to 1350° C. plasma irradiation, or plasma irradiation and mechanical energy, and additionally a film-forming powders obtained by blending color tone adjusters into these hydroxyapatite powders are produced. 1. A film-forming powder for forming a film on a surface of a tooth for use in a jet-device for a tooth , the powder having a mean particle size of 0.5 to 30 m , wherein the film-forming powder is produced by calcining an apatite represented by Ca.M(ZO)Y(wherein X represents 0 to 10; M represents a metal or hydrogen; ZOrepresents PO , CO , CrO , AsO , VO , SiO , SOor GeO; and Y represents a hydroxyl group , a halogen element or a carbonate group) in an inert gas atmosphere at 600 to 1350° C.2. The film-forming powder according to claim 1 , wherein the apatite is hydroxyapatite.3. The film-forming powder according to claim 1 , wherein the inert gas is argon gas or nitrogen gas.4. The film-forming powder according to claim 1 , wherein a color tone adjuster for adjusting a color tone of a tooth crown is further blended in the film-forming powder.5. The film-forming powder according to claim 4 , wherein the color tone adjuster of a tooth crown is at least one selected from titanium oxide claim 4 , zinc oxide claim 4 , and ultramarine blue and a red pigment.6. The film-forming powder according to claim 1 , ...

COMPOSITIONS AND METHOD FOR VISCOSITY-INCREASABLE DENTAL COMPOSITES

Described is a stable, two-component low viscosity composite that is capable to achieve excellent adaptation to walls/substrates due to its intrinsic flow ability and is also capable of rapid viscosity increasing and being manipulated prior to cure by light upon mixing of such a two-paste composite due to one distinguished reaction promoting partial network formation thus to allow a practitioner further manipulate a firm composite. Upon a completed manipulation by the practitioner, such a mixed material should be readily cured into final solid form by using conventional curing light. 1. A dental composition comprising: (a) a base paste comprising a polythiol and a (meth) acrylate , and (b) a catalyst paste comprising a polyene , a (meth) acrylate resin , a curing system and a catalyst;wherein the catalyst is capable of promoting thiol-ene reaction at room temperature.2. The dental composition according to claim 1 , wherein the catalyst paste includes ethoxylated bisphenol A dimethacrylate.3. The dental composition according to claim 1 , wherein the polyene is selected from the group consisting of tricyclo[5.2.1.0]decanedimethanol diacrylate claim 1 , pentaerythritol tetraacrylate claim 1 , polyacrylates and polyvinyl ethers.4. The dental composition according to claim 1 , wherein the polythiols includes pentaerythritol tetra(3-mercaptopropionate) or ethoxylated-trimethylolpropan tri(3-mercaptopropionate.5. The dental composition according to claim 1 , further comprising a photoinitiator.6. The dental composition according to claim 6 , wherein the photoinitiator includes camphorquinone claim 6 , 2 claim 6 ,4 claim 6 ,6-trimethylbenzoyl diphenylphosphine oxide or mixtures thereof.7. The dental composition according to claim 1 , further comprising an additive.8. The dental composition according to claim 8 , wherein the additive includes lauryl gallate or triphenylphosphite.9. The dental composition according to claim 1 , wherein when the catalyst paste includes ...

DENTAL IMPLANT AND METHOD FOR PRODUCING SAME

The purpose of the present invention is to provide a dental implant which enables the formation of a functional periodontal tissue around the implant after the implantation of the implant. The dental implant according to the present invention is characterized in that a cell mass originated from a tooth germ tissue or a periodontal ligament tissue is placed on the surface of the implant and the surface of the implant on which the cell mass is to be placed is the whole or a part of a surface that is surrounded by an alveolar bone of a recipient during the implantation of the implant. 1. A dental implant that enables functional periodontium formation , comprising a tooth germ tissue-derived or a periodontal membrane tissue-derived cell mass is placed on the surface of said implant , andthe surface of said implant on which said cell mass is to be placed is the whole or a part of the surface which is surrounded by the alveolar bone of the recipient at the time of transplantation of said implant.2. The implant according to claim 1 , wherein said tooth germ tissue-derived cell mass is a tooth germ mesenchymal tissue-derived or a dental follicle tissue-derived cell mass.3. The implant according to claim 1 , wherein said cell mass is derived from tooth germ tissue claim 1 , and said tooth germ tissue is in any one developmental stage selected from the group consisting of the cap stage claim 1 , the early bell stage claim 1 , and the late bell stage.4. The implant according to claim 1 , wherein it is correctable after implant transplantation.5. The implant according to claim 1 , wherein said periodontium formed has at least one characteristic among:(i) having functional cementum and functional periodontal membrane, and(ii) having functional nerve fiber.6. The implant according to claim 1 , wherein said implant further comprises a coating layer of a surface coating agent on the entire surface of the implant or a part thereof claim 1 , and said cell mass is placed on the ...

CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME

Disclosed are cement products, methods of forming cement using the cement product, and methods of using the cement product in orthopedic and dental applications. Generally, the disclosed cement product includes a first component and a second component. The first component comprises a polymerizable resin comprising ethylenic unsaturated double bond, a suitable glycidyl group and/or a suitable isocyanate group. The second component includes a compound comprising more than one type of amine selected from the group consisting of primary amine, secondary amines, tertiary amines and quaternary amines. Alternatively, the second component includes a compound comprising a suitable mercapto (SH—) group, a hindered amine or a dimethylthiotoluenediamine (DMTDA). Optionally, the cement product includes a filler and/or a bioactive component to promote bone formation. 1. An orthopedic or dental cement product comprising:a first component comprising a polymerizable resin that comprises an ethylenic unsaturated double bond, a glycidyl ether group, a glycidyl ester group, an ester containing glycidyl ether group, a carbonate containing glycidyl ether group, an isocyanate group, or a combination thereof; anda second component comprising a compound selected from the group consisting of (i) a compound that includes more than one type of amine selected from the group consisting of a primary amine, a secondary amine, a tertiary amine, and a quaternary amine, (ii) a compound that includes a mercapto group, (iii) a compound that includes a hindered amine, (iv) a dimethylthiotoluenediamine (DMTDA) compound, and (v) a combination of two or more compounds of (i)-(iv),wherein the first component and second component are capable of reacting with each other in a polymerization reaction to produce an orthopedic or dental cement, and when the first component and second component are reacted together in a polymerization reaction at room temperature and allowed to set at about 37° C., the reaction ...

REMINERALISATION OF CALCIFIED TISSUE

A cosmetic and/or therapeutic treatment of tissue, such as tooth, is disclosed that effects, for instance, whitening and tissue re-building through mineralisation. Further, a method of performing iontophoresis utilizing an aqueous composition of a remineralising agent to achieve mineralisation is disclosed, as well as a kit for performing the mineralization or re-mineralization. 1. A method of remineralising a tooth comprising:providing a remineralising agent;providing an electrode having a polarity on a surface of a tooth;applying iontophoresis to drive the remineralising agent through the surface of the tooth into a lesion below the surface of the tooth; and, depositing the remineralising agent within the lesion.2. The method according to claim 1 , further comprising:pre-conditioning the tooth to remove protein and/or lipids and then applying the remineralising agent whilst separately, sequentially or simultaneously applying the iontophoresis.3. The method according to claim 1 , further comprising:remineralisation of a hypo-mineralised or a de-mineralised tooth.4. The method according to claim 3 , further comprising:performing a cosmetic treatment of the tooth.5. The method according to claim 4 , further comprising:performing tooth lightening or whitening.6. The method according to claim 1 , further comprising:performing a preventive treatment of tooth erosion.7. The method according to claim 1 , further comprising:remineralising of a bone.8. The method according to claim 1 , wherein the remineralising agent comprises casein phosphopeptide-amorphous calcium phosphate (CPP-ACP).9. The method according to claim 1 , wherein the remineralising agent is a fluoride-containing remineralising agent.10. The method according to claim 9 , wherein the fluoride-containing agent is casein phosphopeptide-amorphous calcium fluoride phosphate (CPP-ACFP).11. The method according to claim 1 , wherein the remineralising agent includes one or more remineralisation enhancers.12. The ...

REMINERALISATION OF CALCIFIED TISSUE

A cosmetic and/or therapeutic treatment of tissue, such as tooth, is disclosed that effects, for instance, whitening and tissue re-building through mineralisation. Further, a method of performing iontophoresis utilizing an aqueous composition of a remineralising agent to achieve mineralisation is disclosed, as well as a kit for performing the mineralization or re-mineralisation. 1. A method of remineralising a tissue comprising:providing a remineralising agent;providing an electrode having a polarity;placing an electrode pad between the electrode and the tissue;driving the remineralising agent into the tissue by applying iontophoresis at a constant voltage or at a constant current; and,depositing the remineralising agent within the tissue.2. The method according to claim 1 , wherein the electrode pad is composed of an ion-conductive material.3. The method according to claim 1 , wherein the electrode pad is composed of an electrically conductive material.4. The method according to claim 1 , wherein the electrode pad is disposable.5. The method according to claim 1 , further comprising:providing the remineralising agent as a gel or a mousse.6. The method according to claim 1 , further comprising:applying the remineralisation agent onto the electrode pad.7. The method according to claim 1 , further comprising:remineralisation of a hypo-mineralised or a de-mineralised tooth.8. The method according to claim 7 , further comprising:performing a cosmetic treatment of a tooth.9. The method according to claim 8 , further comprising:performing tooth lightening or whitening.10. The method according to claim 1 , further comprising:performing a preventive treatment of tooth erosion.11. The method according to claim 1 , further comprising:remineralising of a bone.12. The method according to claim 1 , wherein the remineralising agent comprises casein phosphopeptide-amorphous calcium phosphate (CPP-ACP).13. The method according to claim 1 , wherein the remineralising agent is a ...

FORMULATION

The present invention relates to a hydrogel formulation in which the solid phase is composed of a continuous net work of siloxane bonds and one or more calcium phosphate phases doped with one or more metal dopants. 1. A hydrogel formulation comprising:a solid phase composed of a continuous network of siloxane bonds and one or more calcium phosphate phases doped with one or more metal dopants; andan aqueous phase, or a precursor or anhydrate thereof.2. The hydrogel formulation as claimed in wherein the one or more metal dopants is or includes ions of a rare earth element.3. The hydrogel formulation as claimed in wherein the rare earth element is selected from the group consisting of erbium claim 2 , cerium and ytterbium.4. The hydrogel formulation as claimed in claim 1 , wherein the one or more metal dopants is or includes aluminium ions.5. The hydrogel formulation as claimed in claim 1 , wherein the one or more calcium phosphate phases are fluoride ion-substituted.6. The hydrogel formulation as claimed in claim 1 , wherein the one or more calcium phosphate phases includes fluorapatite.7. The hydrogel formulation as claimed in claim 1 , wherein the one or more calcium phosphate phases are fluoride ion-substituted and the one or more metal dopants is or includes aluminium ions.8. The hydrogel formulation as claimed in claim 1 , wherein the one or more calcium phosphate phases are fluoride ion-substituted and the one or more metal dopants is or includes ions of a rare earth element.9. The hydrogel formulation as claimed in claim 1 , wherein the one or more calcium phosphate phases are fluoride ion-substituted and the one or more metal dopants is or includes aluminium ions and ions of a rare earth element.10. The hydrogel formulation as claimed in claim 1 , wherein the one or more calcium phosphate phases is or includes synthetic hydroxyapatite or a synthetic precursor thereof.11. The hydrogel formulation as claimed in claim 1 , wherein the one or more calcium phosphate ...

FUNCTIONALIZED CALCIUM PHOSPHATE HYBRID SYSTEMS FOR CONFECTIONERY AND FOODSTUFF APPLICATIONS

A method for repairing dentition, including milling beta tricalcium phosphate with sufficiently high energy to substantially distressed its lattice structure, mechanochemically chelating an edible acid thereto to yield functionalized calcium phosphate moieties, and incorporating the functionalized calcium phosphate moieties into an edible material to yield a calcium phosphate delivery system. The calcium phosphate delivery system is introduced into an oral environment and dentition is repaired. The functionalized calcium phosphate moiety is characterized by weakly bonded fumaric acid at least partially wrapped around distressed calcium phosphate particles, and dentition repair occurs at a dentition depth of at least 10 microns below the surface. 1. A method of producing comestibles including functionalized moieties for dental remineralization and whitening , comprising:{'sub': '4', 'distressing the lattice structure of a first predetermined amount of beta tricalcium phosphate to generate a calcium phosphate material characterized by substantially reduced long-range order and the exposure of sufficiently underbonded calcium oxide clusters and POvacancies for acid chelation;'}chelating a second predetermined amount of edible acid to the distressed calcium phosphate material to yield a predetermined quantity of functionalized calcium phosphate moieties; andincorporating functionalized calcium phosphate moieties into a comestible to yield a dental remineralization product;wherein the functionalized calcium phosphate moiety is characterized by weakly bonded fumaric acid at least partially wrapped around distressed calcium phosphate particles;wherein the second predetermined amount is between about 1 and about 30 weight percent of the predetermined quantity of functionalized calcium phosphate moieties; andwherein the dissolution of calcium in an oral environment is at least about ten times greater than that of beta tricalcium phosphate.2. The method of claim 1 , wherein ...

IMPLANTABLE COMPOSITE CONTAINING CARBONATED HYDROXYAPATITE

Provided is an implantable composite which includes a plurality of resorbable ceramic particles with or without a biodegradable polymer. The resorbable ceramic particles can be granules including carbonated hydroxyapatite and tricalcium phosphate in a ratio of 5:95 to 70:30. Some resorbable ceramic particles are granules, which include carbonated hydroxyapatite and β tricalcium phosphate in a ratio of 5:95 to 70:30. The resorbable ceramic particles have a particle size from about 0.4 to about 3.5 mm. The implantable composite is configured to tit at or near a bone defect as an autograft extender to promote bone growth. Methods of using the implantable composite are also provided. 1. An implantable composite comprising a plurality of resorbable ceramic particles , the resorbable ceramic particles comprising carbonated hydroxyapatite and tricalcium phosphate in a ratio from about 5:95 to about 70:30.2. An implantable composite of claim 1 , wherein the implantable composite comprises a biodegradable polymer and the tricalcium phosphate is β tricalcium phosphate.3. An implantable composite of claim 1 , wherein the resorbable ceramic particles are granules having an average diameter in the range from about 0.4 to about 3.5 mm.4. An implantable composite of claim 1 , wherein a resorption rate of the implantable composite containing the carbonated hydroxyapatite increases from about 10% to about 40% when compared to a resorption rate of an implantable composite having resorbable ceramic particles comprising hydroxyapatite and β tricalcium phosphate in a ratio from about 5:95 to about 70:30 but no carbonated hydroxyapatite.5. An implantable composite of claim 2 , wherein the biodegradable polymer comprises one or more poly(L-lactide-co-D claim 2 ,L-lactide) claim 2 , polyglyconate claim 2 , poly(acrylates) claim 2 , poly(anhydrides) claim 2 , poly(hydroxy acids) claim 2 , polyesters claim 2 , poly(orthoesters) claim 2 , poly(alkylene oxides) claim 2 , polycarbonates claim 2 ...

FLUORIDE COMPOSITION AND METHODS FOR DENTAL MINERALIZATION

The present invention relates to compositions and methods for mineralizing a dental surface or subsurface including providing a composition including stabilized ACP and a source of fluoride ions. 112-. (canceled)13. A method of mineralizing a dental surface or subsurface comprising providing a composition to contact the dental surface or subsurface , wherein the composition , prior to contacting the dental surface or subsurface , comprises (i) about 0.01% to 50% by weight casein phosphopeptide-stabilized amorphous calcium phosphate or casein phosphopeptide-stabilized amorphous calcium fluoride phosphate , and , separately , (ii) free fluoride ions in an amount of from at least 400 ppm to about 3 ,000 ppm.14. A method according to claim 13 , wherein the composition is selected from the group consisting of toothpaste; tooth gel; tooth powder; dental creme; liquid dentifrice; mouthwash; troche; chewing gum; gingival massage creme; gargle tablet and dental restorative.15. A method according to claim 13 , wherein the composition comprises sodium fluoride.16. A method for remineralizing a subsurface enamel lesion comprising providing a composition to contact the subsurface enamel lesion claim 13 , wherein the composition claim 13 , prior to contacting the subsurface enamel lesion claim 13 , comprises (i) about 0.01% to 50% by weight casein phosphopeptide-stabilized amorphous calcium phosphate or casein phosphopeptide-stabilized amorphous calcium fluoride phosphate claim 13 , and claim 13 , separately claim 13 , (ii) free fluoride ions in an amount of from at least 400 ppm to about 3 claim 13 ,000 ppm.17. A method according to claim 16 , wherein the composition is selected from the groups consisting of toothpaste; tooth gel; tooth powder; dental creme; liquid dentifrice; mouthwash; troche; chewing gum; gingival massage creme; gargle tablet and dental restorative.18. A method of treating and/or preventing dental caries in tooth enamel comprising providing a composition to ...

CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME

Disclosed are cement products, methods of forming cement using the cement product, and methods of using the cement product in orthopedic and dental applications. Generally, the disclosed cement product includes a first component and a second component. The first component comprises a polymerizable resin comprising ethylenic unsaturated double bond, a suitable glycidyl group and/or a suitable isocyanate group. The second component includes a compound comprising more than one type of amine selected from the group consisting of primary amine, secondary amines, tertiary amines and quaternary amines. Alternatively, the second component includes a compound comprising a suitable mercapto (SH—) group, a hindered amine or a dimethylthiotoluenediamine (DMTDA). Optionally, the cement product includes a filler and/or a bioactive component to promote bone formation. 138-. (canceled)39. An orthopedic cement product comprising:a first component comprising a polymerizable resin that comprises two or more acrylate groups;a second component comprising a compound selected from the group consisting of putrescine (1,4-diaminobutane), spermidine, and spermine; anda bioceramic filler;wherein the first component and second component are capable of reacting with each other in a polymerization reaction to produce an orthopedic or dental cement,wherein when the first component and second component are reacted together in a polymerization reaction at room temperature and allowed to set at about 37° C., the reaction does not exceed a maximum temperature of 60° C. for a period of one minute; andwherein the cement product after setting has a compressive strength of about 20 MPa to about 250 MPa.40. The cement product of claim 39 , wherein the first component comprises a compound selected from the group consisting of bisphenol A glycerolate di(meth)acrylate claim 39 , non-alkoxylated trimethylpropane tri(meth)acrylate (TMPT(M)A) claim 39 , ethoxylated(15) TMPT(M)A claim 39 , ethoxylated (9) TMPT(M ...

PHOSPHATE-BASED DENTAL INVESTMENT MATERIAL

To provide a phosphate-based dental investment material which can used for metal and press ceramic and especially can impart the lubricity to the surface of a press ceramic, and a phosphate-based dental investment material which can be subjected to a flash heating for press ceramic, can obtain sufficient the hardening expansion, and can easily remove the investment material after press molding. A phosphate-based dental investment material of the present disclosure comprising a powder material and a liquid material, wherein the powder material contains (a) magnesium oxide: 5 to 20 wt. %; (b) ammonium dihydrogenphosphate: 8 to 25 wt. % and the liquid material contains (c) aqueous solution including a cation-treated colloidal silica. 1. A phosphate-based dental investment material comprising a powder material and a liquid material , wherein (a) magnesium oxide: 5 to 20 wt. %;', '(b) ammonium dihydrogenphosphate: 8 to 25 wt. % and, 'the powder material contains'} '(c) aqueous solution including a cation-treated colloidal silica.', 'the liquid material contains'}2. The phosphate-based dental investment material according to claim 1 , wherein the content of alkali metals (in terms of oxide) in the (c) aqueous solution including cation-treated colloidal silica is in a range of 0.001 to 0.30 wt. %.3. The phosphate-based dental investment material according to claim 1 , wherein the pH of the (c) aqueous solution including cation-treated colloidal silica is in a range of 8.0 to 10.0.4. The phosphate-based dental investment material according to claim 1 , wherein the cation-treatment is alumina compound treatment.5. The phosphate-based dental investment material according to claim 2 , wherein the pH of the (c) aqueous solution including cation-treated colloidal silica is in a range of 8.0 to 10.0.6. The phosphate-based dental investment material according to claim 2 , wherein the cation-treatment is alumina compound treatment.7. The phosphate-based dental investment material ...

CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME

Disclosed are cement products, methods of forming cement using the cement product, and methods of using the cement product in orthopedic and dental applications. Generally, the disclosed cement product includes a first component and a second component. The first component comprises a polymerizable resin comprising ethylenic unsaturated double bond, a suitable glycidyl group and/or a suitable isocyanate group. The second component includes a compound comprising more than one type of amine selected from the group consisting of primary amine, secondary amines, tertiary amines and quaternary amines. Alternatively, the second component includes a compound comprising a suitable mercapto (SH—) group, a hindered amine or a dimethylthiotoluenediamine (DMTDA). Optionally, the cement product includes a filler and/or a bioactive component to promote bone formation. 138.-. (canceled)39. A method of treating a patient in need of treatment for a bone defect , comprising(i) providing a first component and a second component, wherein the first component comprises a di-acrylate resin, a tri-acrylate resin, a tetra-acrylate resin or a combination thereof, and the second component comprises an aliphatic polyamine containing primary and secondary amine groups and not containing tertiary amine groups, wherein the ratio of primary to secondary amine groups in the aliphatic polyamine is greater than 1, and wherein the first component and second component are capable of reacting with each other in a polymerization reaction to produce a cement;(ii) mixing the first component and second component at room temperature to form a cement, wherein such mixing does not exceed a maximum temperature of 50° C. for a period of one minute;(iii) flowing the cement into voids or crevices within the defective bone of the patient or in between the defective bone of the patient and tissue or an implant, and(iv) allowing the cement to set and thereby repairing the bone defect in the patient;wherein the cement ...

PHOSPHOCALCIC CEMENT COMPOSITION COMPRISING BLOOD

A method for promoting spine fusion inside intersomatic cages, comprising placing a fusion cage between two vertebral bodies, and injecting a bone cement paste inside said fusion cage, said bone cement paste containing a powder component comprising α-tricalcium phosphate (α-TCP) particles having an average size greater than or equal to 9 μm, and a liquid component comprising blood. 1. A method for promoting spine fusion inside intersomatic cages , comprising the following steps:placing a fusion cage between two vertebral bodies, andinjecting a bone cement paste inside said fusion cage, said bone cement paste containing a powder component comprising α-tricalcium phosphate (α-TCP) particles having an average size greater than or equal to 9 μm, and a liquid component comprising blood.2. The method of claim 1 , wherein the liquid component is blood.3. The method of claim 1 , wherein the powder component further comprises at least one calcium phosphate compound other than α-TCP.4. The method of claim 3 , wherein the calcium phosphate compound is selected from the group consisting of hydroxyapatite (HA) claim 3 , amorphous calcium phosphate (ACP) claim 3 , monocalcium phosphate anhydrous (MCPA) claim 3 , monocalcium phosphate monohydrate (MCPM) claim 3 , dicalcium phosphate dihydrate (DCPD) claim 3 , dicalcium phosphate anhydrous (DCPA) claim 3 , precipitated or calcium-deficient apatite (CDA) claim 3 , β-tricalcium phosphate (β-TCP) claim 3 , tetracalcium phosphate (TTCP) claim 3 , and mixtures thereof.5. The method of claim 1 , wherein the powder component comprises:α-tricalcium phosphate (α-TCP) particles having an average size greater than or equal to 9 μm, andat least one calcium phosphate compound selected from the group consisting of: MCPM, DCPD, CDA, and mixtures thereof.6. The method of claim 1 , wherein the powder component comprises at least 70% by weight of α-tricalcium phosphate (α-TCP) particles having an average size greater than or equal to 9 μm claim 1 , ...

ADHESIVE MONOMERS FOR DENTAL MATERIAL

Provided are adhesive monomers for dental materials including compounds represented by the general formula (1) below, in which the core (X) and the terminal group (Y1) are bonded to each other directly or via the linking group (Z): X(Y1)n(Z−Y1)n(1) wherein nrepresents the number of terminal groups (Y1) directly bonded to the core (X), nrepresents the number of terminal groups (Y1) bonded to the core (X) via the linking group (Z), and the sum of nand nis equal to the valence of the core (X); the core (X), the linking group (Z) and the terminal group (Y1) are further defined. The adhesive monomers can enhance adhesive strength to the tooth in dental treatment, and impart high mechanical strength to cured products. 2. The adhesive monomer for dental materials according to claim 1 , wherein the terminal group (Y1) is a phosphorus-containing group represented by the general formula (2) claim 1 , a phosphorus-containing group represented by the general formula (3) claim 1 , a (meth)acryloyl group-containing group (Y2) represented by the general formula (4) claim 1 , or a hydrogen atom.3. The adhesive monomer for dental materials according to claim 1 , wherein the terminal group (Y1) is a phosphorus-containing group represented by the general formula (2) claim 1 , a phosphorus-containing group represented by the general formula (3) claim 1 , or a (meth)acryloyl group-containing group (Y2) represented by the general formula (4).4. The adhesive monomer for dental materials according to claim 1 , wherein in the linking group (Z) n claim 1 , nnand nare each 0 to 20 claim 1 , and the sum of n claim 1 , n claim 1 , nand nis 1 to 20.7. The adhesive monomer for dental materials according to claim 1 , wherein the core (X) is an organic group having a valence of 3 to 12.10. A monomer composition for dental materials comprising the adhesive monomer for dental materials according to .11. The monomer composition for dental materials according to claim 10 , wherein the monomer ...

Phosphorus-containing compounds

Provided are adhesive materials which exhibit high adhesive strength, and compounds which can be blended with the adhesive materials. The compounds are represented by the general formula: X(Y1)n1, in which the core (X) and the terminal group (Y1) are bonded to each other, n1 represents the number of terminal groups (Y1) bonded to the core (X), and n1 is equal to the valence of the core (X); the core (X) is a C1-200 polyvalent organic group having a valence of not less than 3 containing an oxygen atom or a nitrogen atom in which an atom bonded to the terminal group (Y1) is the oxygen atom or the nitrogen atom; and the terminal group (Y1) is further defined.

Deposition of discrete nanoparticles on an implant surface

A dental implant made of a material comprising titanium. The implant includes a head portion having a non-rotational feature, a lowermost end opposing the head portion, and a threaded bottom portion for engaging bone between the head portion implant and the lowermost end. The implant further includes a nanocrystalline surface formed on at least a portion of the implant. The nanocrystalline surface includes discrete nanocrystals deposited on a roughened surface of the implant. The roughened surface includes at least one of a grit-blasted surface or an acid-etched surface. A portion of the roughened surface is exposed between at least some of the discrete nanocrystals such that the exposed roughened portion between the discrete nanocrystals is capable of contacting bone.

An electrolyte composition containing zinc and silicon in a plasma electrolytic oxidation process and a method for manufacturing dental implants coated by hydroxyapatite containing zinc and silicon ions using the composition

In the present invention, surface treatment of dental implants using a plasma electrolytic oxidation process is performed for a titanium-based bioalloy to make the manufacturing process simple, and reduce the implant preparation time and treatment time. An electrolyte composition of the plasma electrolytic oxidation process contains calcium acetate monohydrate, calcium glycerophosphate, zinc acetate, sodium metasilicate nonahydrate, and distilled water.

Method for preparing glass-ceramics, capable of adjusting machinability or translucency through change in temperature of heat treatment

본 발명은 실리케이트를 주성분으로 하는 리튬 디실리케이트 결정화 유리 제조 방법에 관한 것으로, 더욱 상세하게는 1차 열처리 또는 2차 열처리를 이용하여 결정의 크기에 따른 가공성 또는 투광성 조절이 가능한 결정화 유리 제조 방법에 관한 것이다. 이를 위해 본 발명의 실리카 결정상을 포함하는 결정화 유리 제조 방법은 유리 조성물을 400 내지 850℃에서 1차 열처리를 수행하며, 1차 열처리에 의해 5 내지 2000nm의 리튬 디실리케이트 결정상과 실리카 결정상이 생성됨을 특징으로 한다. 이를 위해 본 발명의 실리카 결정상을 포함하는 결정화 유리 제조 방법은 1차 열처리 이후에 780 내지 880℃에서 2차 열처리를 수행하며, 2차 열처리의 온도에 의해 투광성이 조절됨을 특징으로 한다. The present invention relates to a method for producing a crystallized glass of lithium disilicate having a silicate as a main component, and more particularly, to a method for producing a crystallized glass capable of controlling workability or light transmittance according to the size of a crystal by using a primary heat treatment or a secondary heat treatment will be. To this end, the method for producing a crystallized glass including the silica crystal phase of the present invention is characterized in that the glass composition is subjected to a first heat treatment at 400 to 850 ° C, and a lithium disilicate crystal phase and a silica crystal phase are generated by 5 to 2000 nm by a first heat treatment . To this end, the method for producing a crystallized glass including the silica crystal phase of the present invention is characterized in that the second heat treatment is performed at 780 to 880 ° C after the first heat treatment, and the light transmittance is controlled by the temperature of the second heat treatment.

An electrolyte composition containing magnesium and silicon in a plasma electrolytic oxidation process and a method for manufacturing dental implants coated by hydroxyapatite containing magnesium and silicon ions using the composition

The present invention relates to a method for manufacturing implants, which uses an electrolyte solution containing magnesium and silicon to form the surface of a porous oxidation film containing magnesium, silicon ions, calcium and phosphorus on the surface of the dental implants through a plasma electrolytic oxidation method, thereby improving bioactivity, wherein the method comprises the following steps: a titanium alloy preparation step; an input step; a plasma forming step; and a drying step.

Dental compositions with calcium phosphorus releasing glass

The present application provides a glass composition comprising 10-50% by weight CaO, at least 15% and less than 50% by weight P 2 O 5 , less than 3% by weight Al 2 O 3 , less than 10% by weight Li 2 O, Na 2 O, and K 2 O combined, and 0-60% by weight of SrO, MgO, BaO, ZnO, or combinations thereof; dental compositions comprising the glass composition, and methods of making and using such dental compositions.

Lithium silicate glasses or glass ceramics, method for production thereof and use thereof

The invention relates to glass ceramics based on the lithium metasilicate system (Li 2 O.SiO 2 (Li 2 SiO 3 )), which are mechanically processible in a simple manner in an intermediate stage of the crystallization and, after complete crystallization, represent a high-strength, highly translucent and chemically stable glass ceramic.

Fluoride composition and methods for dental mineralization

The present invention relates to compositions and methods for mineralizing a dental surface or subsurface including providing a composition including stabilized ACP and a source of fluoride ions.

Remineralisation of calcified tissue

A cosmetic and/or therapeutic treatment of tissue, such as tooth, is disclosed that effects, for instance, whitening and tissue re-building through mineralisation. Further, a method of performing iontophoresis utilizing an aqueous composition of a remineralising agent to achieve mineralisation is disclosed, as well as a kit for performing the mineralization or remineralisation.

ANTIBACTERIAL DENTAL COMPOSITIONS CONTAINING POLYMERIZABLE METALLIC METACHRYLATES

composições odontológicas antibacterianas contendo metacrilatos metálicos polimerizáveis. a invenção refere-se a composições odontológicas poliméricas que contenham metacrilatos metálicos na formulação de sistemas adesivos, selantes, cimentos e compósitos. as composições apresentam variadas aplicações em odontologia em prótese dentária, dentística, ortodontia, odontopediatria, implantodontia, endodontia. em particular, a presente invenção refere-se a composições odontológicas poliméricas antimicrobianas que contenham metacrilatos metálicos na formulação, como metacrilato de cálcio, de estanho, de cobre, de prata, de níquel, de titânio, de ferro. antibacterial dental compositions containing polymerizable metal methacrylates. the invention relates to polymeric dental compositions that contain metal methacrylates in the formulation of adhesive systems, sealants, cements and composites. the compositions have various applications in dentistry in dental prosthesis, dentistry, orthodontics, pediatric dentistry, implantology, endodontics. in particular, the present invention relates to antimicrobial polymeric dental compositions that contain metal methacrylates in the formulation, such as calcium, tin, copper, silver, nickel, titanium, iron methacrylate.

An electrolyte composition containing manganese and silicon in a plasma electrolytic oxidation process and a method for manufacturing dental implants coated by hydroxyapatite containing manganese and silicon ions using the composition

본 발명은 치과용 임플란트 표면에 양극산화법인 플라즈마 전해 산화법(Plasma Electrolytic Oxidation)을 이용하여 망가니즈 이온을 포함하여 뼈의 구성원소인 칼슘과 인이 포함된 다공성 표면을 형성시키는 것으로, 더욱 상세하게는 인체를 이루고 있는 많은 이온중에 세포부착과 골 형성으로부터 중요한 역할을 하는 망가니즈와 실리콘 이 함유된 전해질 용액을 사용하여 치과 임플란트 표면에 망가니즈 및 실리콘 이온과 칼슘 및 인이 포함된 다공성 산화 피막의 표면을 플라즈마 전해 산화법으로 형성하여 생체활성을 향상시키는 임플란트 제조방법이며, 그 과정은 치과용 티타늄합금을 순차적으로 연마, 미세연마 및 초음파 세척하는 티타늄합금 준비단계, 상기 준비단계에서 준비된 티타늄합금을 전기분해조 양극에 설치하고, 음극은 백금을 설치한 후 전해질 용액을 투입하는 투입단계, 일정한 전압과 전류밀도를 가하여 플라즈마를 생성시켜 티타늄합금에 산화 피막을 형성하는 플라즈마 형성단계 및 상기 플라즈마 형성단계에서 티타늄합금에 산화피막이 형성된 후 에탄올 및 증류수 세척 후 건조시키는 건조단계를 포함하는 플라즈마 전해 산화 공정에서 망가니즈 및 실리콘이 함유된 전해질 조성물 및 그 조성물을 이용하여 망가니즈 및 실리콘 이온을 함유하는 수산화아파타이트가 코팅된 치과용 임플란트 제조방법이다. 상기 플라즈마 전해 산화 공정에서 망가니즈 및 실리콘이 함유된 전해질 조성물 및 그 조성물을 이용하여 망가니즈 및 실리콘 이온을 함유하는 수산화아파타이트가 코팅된 치과용 임플란트 제조방법에 의한 효과는 티타늄계 생체합금에 플라즈마 전해 산화공정을 이용하여 치과용 임플란트 표면 처리함으로써 제조공정 과정이 간편하고, 임플란트 제조 시간 및 치료 기간을 저감시키는 효과가 있고, 플라즈마 전해 산화법으로 망가니즈와 실리콘 이온을 복합적인 치환을 통해 생체적합성을 지닌 다공성 산화막을 생성하였으며, 종래 금속 산호막보다 두껍고 치밀한 산화막을 제조하며, 망가니즈 및 실리콘 이온의 생체활성물질을 포함하여 생체적합성을 증가시켜 치과용 임플란트의 초기 고정력을 높이고, 제조 과정의 간편함과 치료기간을 줄이므로써 제조시간 및 제조단가를 현저하게 절감 시킨다. The present invention relates to a method for forming a porous surface containing calcium ions and phosphorus, which are components of bone, including manganese ions by using plasma oxidation method (Plasma Electrolytic Oxidation), which is anodic oxidation method, on a surface of a dental implant. More specifically, The surface of the porous oxide film containing manganese and silicon ions and calcium and phosphorus on the surface of the dental implants is removed by using an electrolytic solution containing manganese and silicon, The present invention relates to a method for manufacturing an implant that is formed by a plasma electrolytic oxidation method and improved in biological activity. The process comprises the steps of preparing a titanium alloy for sequentially polishing, fine polishing and ultrasonic cleaning the dental titanium alloy, And the anode is platinum, and then the cathode A ...

Mini-dental implant

본 발명은 동물 모델을 위한 미니-치아 임플란트의 제작 및 식립 방법에 관한 것이다. 본 발명에 따른 미니-치아 임플란트는 가장 작은 크기의 동물 모델인 생쥐에 적용 가능하기 때문에 다양한 크기의 동물 모델을 이용한 임플란트 실험에 사용할 수 있을 뿐만 아니라 도입되는 세포 시트의 종류 및 순서에 따라 사람의 자연치아와 유사한 환경을 조성할 수 있기 때문에 다양한 질환 및/또는 다양한 물질과 임플란트와의 연관관계에 대한 연구에 효과적으로 사용될 수 있을 것으로 기대된다. The present invention relates to the production and placement of mini-dental implants for animal models. Since the mini-dental implant according to the present invention can be applied to a mouse, which is the smallest animal model, it can be used for an implant experiment using animal models of various sizes, It is anticipated that it can be used effectively in research on the relationship between various diseases and / or various materials and implants because it can create a tooth-like environment.

Methods and systems for mineralization of demineralized tissue

Disclosed are systems, methods, compositions and kits for mineralizing tissue, particularly dental tissue. The methods, compositions and kits may be used to strengthen and prevent weakening of the tissue. For example, the methods, compositions and kits may be used for treating and filling cavities in teeth caused by tooth decay.

Hard tissue regeneration material and hard tissue regeneration method

Provided are a hard tissue restoration material, which is excellent in hard tissue restoration ability, extremely effective in promoting recalcification of dental enamel, and excellent in protection properties and aesthetic properties, and a hard tissue restoration method. The hard tissue restoration material according to the present invention is a biocompatible ceramic film with flexibility and pliability that is obtained, for example, by immersing a substrate, having the biocompatible ceramic film formed thereon, in a solvent, which does not dissolve the biocompatible ceramic but dissolves at least a portion of the substrate, to dissolve or separate the substrate. Also, with the hard tissue restoration method according to the present invention, the hard tissue restoration material according to the present invention is bonded to or wound around a hard tissue defect site.

System for dental filling material or implant material consists of water-based hydration liquid and powdered material comprising water-soluble phosphate or phase

A system for dental filling material or implant (1) material, consists of water based hydration liquid and powdered material. The binder phase of powdered material consists of calcium-based cement system. The powdered material and/or hydration liquid comprises water-soluble phosphate or phase. The system forms apatite during hydration. A system for dental filling material or implant material and for bonding dental filling material or implant material between tooth and bone, respectively, consists of water-based hydration liquid and powdered material. The binder phase of powdered material consists of calcium based cement system. The powdered material is saturated with liquid, which is reacted with binder phase to hydrate chemically bonded ceramic material. The powdered material and/or hydration liquid comprises water-soluble phosphate or phase which forms water-soluble phosphate. The system forms apatite during hydration. Independent claims are also included for the following: (1) powdered material; (2) aqueous hydration liquid for powdered material; (3) implant material comprising substrate; and (4) method for achieving bonding dental filling material and implant material between tooth and bone, respectively.

MULTIPOROUS HYDROXYAPATITE-TRICALCIUM PHOSPHATE CERAMIC COMPOSITES(biphasic calcium phosphate: BCP) USING AMMONIUM HYDROGEN CARBONATE AS SUPPORT BODY AND METHOD FOR MANUFACTURING THEREOF

본 발명은 지지체를 이용하여 수산화아파타이트와 베타형 인산 삼칼슘(β-TCP)의 혼합물을 소결하여 뼈와 유사한 탄성계수를 가지며 세포와의 결합력을 높인 다기공의 수산화아파타이트-베타형 인산 삼칼슘 세라믹 복합재 및 이의 제조방법에 관한 것으로, 수산화아파타이트 100 중량부, 베타형 인산 삼칼슘 13 내지 30중량부, 탄산수소암모늄 5 내지 35중량부, 거친 기공형성제 1 내지 3 중량부, 그리고 소결촉진제 0.5 내지 1.5 중량부를 혼합하는 단계, 상기 혼합된 분말을 급속소결법으로 소결하는 단계, 및 소결 후 열처리 단계를 포함하는 세라믹 복합재의 제조방법을 제공한다. The present invention relates to a method for sintering a mixture of apatite hydroxide and beta-type tricalcium phosphate (β-TCP) using a support to obtain a multi-pore hydroxyapatite-beta type calcium phosphate tricalcium phosphate The present invention relates to a composite material and a method for producing the composite material, which comprises 100 parts by weight of apatite hydroxide, 13 to 30 parts by weight of beta-form tricalcium phosphate, 5 to 35 parts by weight of ammonium hydrogen carbonate, 1 to 3 parts by weight of coarse pore- A sintering step of sintering the mixture powder, and a heat treatment step after the sintering step. The present invention also provides a method for producing a ceramic composite material.

지지체 탄산수소암모늄을 이용한 다기공의 수산화아파타이트-베타형 인산 삼칼슘 세라믹 복합재 및 이의 제조방법

본 발명은 지지체를 이용하여 수산화아파타이트와 베타형 인산 삼칼슘(β-TCP)의 혼합물을 소결하여 뼈와 유사한 탄성계수를 가지며 세포와의 결합력을 높인 다기공의 수산화아파타이트-베타형 인산 삼칼슘 세라믹 복합재 및 이의 제조방법에 관한 것으로, 수산화아파타이트 100 중량부, 베타형 인산 삼칼슘 13 내지 30중량부, 탄산수소암모늄 5 내지 35중량부, 거친 기공형성제 1 내지 3 중량부, 그리고 소결촉진제 0.5 내지 1.5 중량부를 혼합하는 단계, 상기 혼합된 분말을 급속소결법으로 소결하는 단계, 및 소결 후 열처리 단계를 포함하는 세라믹 복합재의 제조방법을 제공한다.

High strength bio:active composite ceramic material - used for dental and orthopaedic implants, contg. e.g. oxide(s) of titanium, zirconium and aluminium

전복 패각을 이용한 생체재료 및 그 제조방법

본 발명은 전복 패각을 수집 및 세척하는 제1단계, 제1단계의 세척된 전복 패각을 분쇄하여 소화하는 제2단계, 소화하여 생성된 산화칼슘 (Calcium oxide, CaO)을 인산화하여 교반 숙성하는 제3단계, 교반, 숙성된 침전물을 걸러내고 세척하는 제4단계 및 침전물을 고온에서 소결하여 수산화인회석(Ca 10 (PO 4 )(OH) 2 )를 생성하는 제5단계를 포함하는 생체재료 제조방법 및 그 생체재료를 제공한다.

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미니-치아 임플란트

본 발명은 동물 모델을 위한 미니-치아 임플란트의 제작 및 식립 방법에 관한 것이다. 본 발명에 따른 미니-치아 임플란트는 가장 작은 크기의 동물 모델인 생쥐에 적용 가능하기 때문에 다양한 크기의 동물 모델을 이용한 임플란트 실험에 사용할 수 있을 뿐만 아니라 도입되는 세포 시트의 종류 및 순서에 따라 사람의 자연치아와 유사한 환경을 조성할 수 있기 때문에 다양한 질환 및/또는 다양한 물질과 임플란트와의 연관관계에 대한 연구에 효과적으로 사용될 수 있을 것으로 기대된다.

Cement products and methods of making and using the same

Disclosed are cement products, methods of forming cement using the cement product, and methods of using the cement product in orthopedic and dental applications. Generally, the disclosed cement product includes a first component and a second component. The first component comprises a polymerizable resin comprising ethylenic unsaturated double bond, a suitable glycidyl group and/or a suitable isocyanate group. The second component includes a compound comprising more than one type of amine selected from the group consisting of primary amine, secondary amines, tertiary amines and quaternary amines. Alternatively, the second component includes a compound comprising a suitable mercapto (SH—) group, a hindered amine or a dimethylthiotoluenediamine (DMTDA). Optionally, the cement product includes a filler and/or a bioactive component to promote bone formation.

Compositions containing theobromine and their use in treating tooth hypersensitivity

Compositions and methods for reducing oral sensitivity, increasing the systemic health of a mammal, occluding a dentinal tubule within a mammalian tooth, and/or depositing a precipitate on the surface of a mammalian tooth are provided, said compositions comprising theobromine (3,7-dimethylxanthine, the principal alkaloid in Theobroma cacao ).

One-component-type dentinal tubule sealant

A dentinal tubule sealant including apatite particles (A) having an average particle diameter of 500 nm or less, a filler (B) having an average particle diameter of 1 to 10 μm, and a dispersant (C), wherein the weight ratio (A/B) of the apatite particles (A) to the filler (B) is 0.05 to 15, the dentinal tubule sealant contains 15 to 95 parts by weight of the dispersant (C) relative to 100 parts by weight in total of the apatite particles (A) and the filler (B), and the total amount of the apatite particles (A), the filler (B), and the dispersant (C) is 85 parts by weight or more relative to 100 parts by weight of the dentinal tubule sealant. There is thereby provided a dentinal tubule sealant excelling in dentinal tubule sealability immediately after treatment, durability of dentinal tubule sealing, ease of operation, and storage stability.

Methods of treatment of the dental pulp and filling root canals using water-based material

A dental composition comprising: a) about 1 to about 80% by weight of particulate material including: (i) calcium silicate, calcium aluminate, tetracalcium aluminoferrite, calcium phosphate, calcium sulfate, silica, alumina, calcium oxide, calcium hydroxide, or mixtures thereof; wherein the particulate material has an average particle size of less than 40 microns; and b) about 1 to about 50% by weight liquid carrier including: (i) water-soluble polymer, and (ii) water.

Production of dental shaped parts composed of porous glass

The invention discloses a blank for producing dental shaped parts which consists entirely of porous glass without crystalline portions. The density of the blank is between 50% and 95% of its theoretical density. It has a discoidal shape with a diameter of at least 20 mm. The blank is produced by a process in which glass powder is first pressed at a pressure of between 10 MPa and 300 MPa and this green body is (pre-)sintered at a temperature of between 580° C. and 750° C. to form a blank of porous glass without crystalline portions. From the obtained blank, monolithic dental shaped parts can be obtained by mechanical processing followed by sintering, wherein a process according to the invention for stabilizing the shape of the shaped parts is used.

Dental devices

The present invention is a dental device comprising natural and sustainable materials. These materials are derived from the nut of the tangua palm tree that may be fashioned into devices for human and animals when replacing one or more teeth of the subject.

Curable calcium phosphate composition for biological hard tissue repair, bone repair material, and various dental materials

The present invention provides a curable calcium phosphate composition for biological hard tissue repair that yields a cured product excellent in durability in a wet environment such as in a body or an oral cavity. The present invention relates to a curable calcium phosphate composition for biological hard tissue repair, including tetracalcium phosphate particles (A), calcium hydrogen phosphate particles (B), calcium carbonate particles (C), and water (D), the curable calcium phosphate composition including 5 to 75 parts by weight of the tetracalcium phosphate particles (A), 10 to 70 parts by weight of the calcium hydrogen phosphate particles (B), and 2 to 50 parts by weight of the calcium carbonate particles (C) per 100 parts by weight of the total of the tetracalcium phosphate particles (A), the calcium hydrogen phosphate particles (B), and the calcium carbonate particles (C).

Methods of treatment of the dental pulp and filling root canals using water-based material

A dental composition comprising: a) about 1 to about 80% by weight of particulate material including: (i) calcium silicate, calcium aluminate, tetracalcium aluminoferrite, calcium phosphate, calcium sulfate, silica, alumina, calcium oxide, calcium hydroxide, or mixtures thereof; and b) about 1 to about 50% by weight liquid carrier including: (i) water-soluble polymer, (ii) surfactant, the surfactant is selected from the group consisting of alkyl sulfates, alkyl ether sulfates, and sarcosinates, and mixtures thereof; and (iii) water; wherein the particulate and liquid carrier being mixed together to form a hydrate gel material that can harden.

Cement products and methods of making and using the same

Disclosed are cement products, methods of forming cement using the cement product, and methods of using the cement product in orthopedic and dental applications. Generally, the disclosed cement product includes a first component and a second component. The first component comprises a polymerizable resin comprising ethylenic unsaturated double bond, a suitable glycidyl group and/or a suitable isocyanate group. The second component includes a compound comprising more than one type of amine selected from the group consisting of primary amine, secondary amines, tertiary amines and quaternary amines. Alternatively, the second component includes a compound comprising a suitable mercapto (SH—) group, a hindered amine or a dimethylthiotoluenediamine (DMTDA). Optionally, the cement product includes a filler and/or a bioactive component to promote bone formation.

Use of bone adhesive for apical sealing a tooth root canal

A method and kit for the apical sealing an tooth root canal and for improving root canal fillings are described. Also described is a method for using bone glue as an apical stop for obturating root canals.

Lithium disilicate-apatite glass ceramic with transition metal oxide

Lithium disilicate-apatite glass ceramics comprising transition metal oxide are described which are characterized by a high chemical stability, and the translucence of which can be adjusted as desired, and which can therefore be used in particular as restoration material in dentistry.

Implant coated with net-shaped or island-shaped low-crystallized hydroxyapatite and method for coating same

The present disclosure relates to a method for coating a surface of a titanium implant with low crystalline hydroxyapatite having network- or island-like morphology and to an implant coated by such method.

Anti periodontitis-causing microorganism agent and medical or dental materials using the same

A medical or dental material can be prepared by using, as an active ingredient, at least one of a protamine, and derivatives thereof and hydrolysates thereof, or a complex of at least one of a protamine, and derivatives thereof and hydrolysates thereof with an anionic high molecular weight compound. As a result, an antibacterial agent against periodontal disease-causing bacteria can be provided, which is highly safe without concern of a side effect. A medical or dental material can be also provided, which exhibits antimicrobial activity on periodontal disease-causing bacteria and additionally has insolubility in water and good formability.

Composition

The present invention relates to a photosensitive composition comprising synthetic nanocrystalline hydroxyapatite or a synthetic precursor thereof doped with a rare earth ion, the use of the composition in restorative or cosmetic dentistry, a process for preparing the composition and a method of generating an image of an exposed dentinal surface of a tooth.

Method for inhibiting dentinal hypersensitivity

A method for inhibiting dentinal hypersensitivity by applying a dentinal hypersensitivity inhibitor on a dentin surface. The dentinal hypersensitivity inhibitor contains at least one tetracalcium phosphate particle, an alkali metal salt of phosphoric acid, and at least one acidic calcium phosphate particle. The tetracalcium phosphate particle has an average particle diameter of 0.5 to 40 μm. The dentinal hypersensitivity inhibitor contains a blended amount of the tetracalcium phosphate particle of 5 to 55 parts by weight relative to 100 parts by weight of a whole amount of the dentinal hypersensitivity inhibitor and a blended amount of the alkali metal salt of phosphoric acid of 1 to 100 parts by weight relative to 100 parts by weight of the tetracalcium phosphate particle.