Catalyst

MIXTURES OF CHIRAL MONOPHOSPHORUS COMPOUNDS USED AS LIGAND SYSTEMS FOR ASYMMETRIC TRANSITION METAL CATALYSIS

PROCESS FOR THE PREPARATION OF 1-SUBSTITUTED 2-METHYL-TETRAHYDROPYRIMIDINES

PROCESS FOR THE PREPARATION OF 1-SUBSTITUTED 2-METHYL-TETRAHYDRO-PYRIMIDINES 1-substituted 2-methyl-tetrahydropyrimidines are prepared by reacting an N-substituted propylene diamine with an acetoacetic acid ester or amide at a temperature of from 0 to 80.degree.C and removing the water produced in the reaction at a temperature of from 0 to 80.degree.C.

MIXTURES OF CHIRAL MONOPHOSPHORUS COMPOUNDS USED AS LIGAND SYSTEMS FOR ASYMMETRIC TRANSITION METAL CATALYSIS

The invention relates to certain chiral transition metal catalysts, to the metal of which at least two structurally different monophosphorus ligands are bonded, at least one of said monophosphorus ligands being chiral. Said chiral transition metal catalysts are suitable as catalysts for use in asymmetric transition metal-catalyzed reactions, providing better enantioselectivities than in cases where only one structurally defined ligand is used.

USE OF AN IONIC COMPOUND, DERIVED FROM MALONONITRILE AS A PHOTOINITIATOR, RADICAL INITIATORS OR CATALYSER IN POLYMERIZATION PROCESSES OR AS A BASIC DYE

La présente invention concerne l'utilisation de composés ioniques dérivés du malononitrile comme photoinitiateur source d'acide catalyseur dans un procédé de polymérisation ou de réticulation de monomères ou de prépolymères capables de réagir par voie cationique, ou comme catalyseur dans un procédé pour la modification de polymères. L'invention vise également l'utilisation de composés ioniques dérivés du malononitrile dans les colorants cationiques.

SURFACE MODIFIED CARBONATE MATERIALS

Greffage d'un polymère à la surface d'un matériau carboné comportant des fonctions carboxyles, amines et/ou hydroxyles à sa surface. On met ce matériau en suspension dans une solution comprenant le polymère à greffer, lequel comporte une fonction carboxyle, amine et/ou hydroxyle, la solution comprenant aussi un solvant du polymère. On effectue ensuite un traitement provoquant la déshydratation en une fonction carboxyle, d'une fonction amine et/ou hydroxyle et l'on greffe ainsi le polymère sur le matériau carboné par des liens esters ou amides. Utilisation dans la cathode ou l'anode d'un générateur électrochimique, dans un matériau polymère peu polaire, dans une encre, et comme dépôt conducteur sur un plastique flexible utilisé comme contact électrique, comme protection électromagnétique ou comme protection antistatique. Grafting of a polymer on the surface of a carbonaceous material comprising carboxyl, amine and / or hydroxyl functions on its surface. This material is suspended in a solution comprising the polymer to graft, which has a carboxyl, amine function and / or hydroxyl, the solution also comprising a solvent for the polymer. We then performs a treatment causing dehydration by a carboxyl function, an amine and / or hydroxyl function and one grafts thus the polymer on the carbonaceous material by ester links or amides. Use in the cathode or anode of a generator electrochemical, in a slightly polar polymer material, in an ink, and as a conductive deposit on a flexible plastic used as a contact electric, as electromagnetic protection or as antistatic protection.

TRANSITION METAL-CATALYZED REACTIONS BASED ON CHIRAL AMINE OXAZOLINYL LIGANDS

The invention is drawn to novel transition metal catalysts for the pratical synthesis of important chiral molecules. The transition metal catalysts comprise chiral ligands based on chiral amine oxazolinyl ligands. The invention includes methods of making the catalysts, and methods of performing reactions using the catalysts.

Process for preparing optically active nitro compounds and cyano compounds

本发明的课题在于采用简便且实用的迈克尔加成反应高效率且高立体选择性地制造硝基化合物和氰基化合物。由此，本发明提供一种方法，其通过将光学活性含氮化合物和周期表第VIII族金属络合物相互作用得到的金属络合物用于权利要求1所述的化学式(A)所示化合物和化学式(B)所示化合物的不对称迈克尔加成反应，制造化学式(C)所示光学活性硝基化合物和氰基化合物。

Catalysts comprising N-substituted cyclic imides and processes for prepairing organic compounds with catalysts

本发明的催化剂包括具有式(I)所示的N－取代环二酰亚胺骨架的二酰亚胺化合物，其中R为羟基保护基团。优选R为可水解的保护基团，例如R可以是从酸中消除OH基团而得到的基团。这种酸包括例如羧酸，磺酸，碳酸，氨基甲酸，硫酸，硝酸，磷酸和硼酸。该催化剂可以包括二酰亚胺化合物与金属化合物的组合。在该催化剂的存在下，使能够形成自由基的化合物(A)与捕获自由基的化合物(B)反应，从而生成化合物(A)与化合物(B)的加成或取代反应产物或其衍生物。在温和条件下通过加成，取代等反应，该催化剂可以高产率和高选择性制备有机化合物。

IONIC LIQUIDS WITH A CATION COMPRISING A BASIC MOIETY

Use of ionic liquids as solvents in base-catalysed chemical reactions wherein the ionic liquid is composed of at least one species of cation and at least one species of anion, characterised in that a cation of the ionic liquid comprises a positively charge moiety and a basic moiety, and further wherein such ionic liquids may be used as promoters or catalysts for the chemical reactions.

ASYMMETRIC CATALYSIS BASED ON CHIRAL PHOSPHOLANES AND HYDROXYL PHOSPHOLANES

Chiral phosphine ligands derived from chiral natural products including D-mannitol and tartaric acid. The ligands contain one or more 5-membered phospholane rings with multiple chiral centers, and provide high stereoselectivity in asymmetric reactions.

MAIN-GROUP METAL-BASED ASYMMETRIC CATALYSTS AND APPLICATIONS THEREOF

The present invention relates to a method and catalysts for the stereoselective addition of a nucleophile to a reactive π-bond of a substrate. The chiral, non-racemic catalysts of the present invention constitute the first examples of catalysts for nucleophilic additions that comprise a main-group metal and a tri- or tetra-dentate ligand.

SURFACE MODIFIED CARBONATE MATERIALS

Disclosed is a method for grafting a polymer onto the surface of a carbonate material with carboxyl, amine, and/or hydroxyl functions on its surface. Said material is placed in suspension in a solution including the polymer to be grafted, which has a carboxyl, amine, and/or hydroxyl function, said solution also being comprised of a polymer solvent. A process which stimulates the dehydration into a carboxyl function of an amine and/or hydroxyl function is then performed, and the polymer is grafted onto the carbonate material using ester or amide links. The invention can be used in the cathode or naode of an electrochemical generator, in polymer materials with low polar properties, in ink, and also as a conductive coating on flexible plastic used as an electrical contact, as electromagnetic shielding, or as static protection.

POLYMER-SUPPORTED METAL COMPLEX CATALYST

... [PROBLEMS] A polymer-supported rhodium(II) catalyst; and a reaction employing this catalyst which is the addition of an α-diazocarbonyl compound to a carbon-carbon multiple bond, insertion thereof into C-H and X-H (X = N, O, S, Se, Si, etc.) bonds, or rearrangement/addition cyclization thereof triggered by ylide formation. [MEANS FOR SOLVING PROBLEMS] An insoluble polymer produced by the copolymerization of a styrene derivative substituted by a carboxylic acid, styrene, and a linear alkane substituted by a vinylbenzyloxy group at each end and a rhodium(II) carboxylate complex are subjected to ligand exchange reaction to produce a novel insoluble-polymer-supported rhodium(II) complex. Namely, it is a polymer-supported metal complex catalyst which is obtained by depositing a metal on a crosslinked polymer and is represented by the following formula (chemical formula 1): [Chemical formula 1] wherein M1 and M2 each represents rhodium, etc.; X represents oxygen, etc.; R4 represents alkyl, etc ...

MALONONITRILE-DERIVATIVE ANION SALTS, AND THEIR USES AS IONIC CONDUCTING MATERIALS

The invention is related to ionic compounds, derivatives of malononitrile, in which the anionic load has been displaced. An ionic compound disclosed by the invention includes an anionic portion combined with at least one cationic portion M+m in sufficient numbers to ensure overall electronic neutrality; the compound is further comprised of M as a hydroxonium, a nitrosonium NO+, an ammonium -NH¿4?+, a metallic cation with the valence m, an organic cation with the valence m, or an organometallic cation with the valence m. The anionic portion corresponds to one of the formulas R¿D?-Y-C(C≡N)2?-¿ or Z-C(C≡N)¿2?-, wherein Z is an electroattractive group, R¿D? is an organic radical, and Y is a carbonyl, a thiocarbonyl, a sulphonyl, a sulphinyl, or a phosphonyl. The compounds can be used notably for ionic conducting materials, electronic conducting materials, colorants, and the catalysis of various chemical reactions.

Diphosphines, their complexes with transisition metals and their use in asymmetric synthesis

The invention relates to novel diphosphines, in optically pure or racemic form, of formula (I):in which:R1 and R2 are a (C5-C7)cycloalkyl group, an optionally substituted phenyl group or a 5-membered heteroaryl group; andA is (CH2-CH2) or CF2.The invention further relates to the use of a compound of formula (I) as a ligand for the preparation of a metal complex useful as a chiral catalyst in asymmetric catalysis, and to the chiral metal catalysts comprising at least one ligand of formula (I).

Perfluorinated amide salts and their uses as ionic conducting materials

The invention concerns ionic compounds in which the anionic load has been delocalized. A compound disclosed by the invention is comprised of an amide or one of its salts, including an anionic portion combined with at least one cationic portion M<+m >in sufficient numbers to ensure overall electronic neutrality; is the compound is further comprised of M as a hydroxonium, a nitrosonium NO<+>, an ammonium -NH4+, a metallic cation with the valence m, an organic cation with the valence m, or an organometallic cation with the valence m. The anionic portion matches the formula RF-SOx-N-Z, wherein RF is a perfluorinated group, x is 1 or 2, and Z is an electroattractive substituent. The compounds can be used notably for ionic conducting materials, electronic conducting materials, colorants, and the catalysis of various chemical reactions.

Phase selective polymer supports for catalysis

Phase-selective soluble polymer supports for catalysts are described. The catalysts utilize polystyrene copolymers having enhanced solubility in nonpolar solvents. Other catalysts of the invention utilize polyisobutylene supports. Methods of catalyzing chemical reactions using latent biphasic solvents are also disclosed.

OPTISCH AKTIVE FLUORIERTE BINAPHTHOL-DERIVATE

PROCEDURE IN MICRO-CHANNEL REACTORS WITH BOUND CATALYST AND A BOUND CATALYST OR A BOUND CHIRALE AID CONTAINING SYSTEMS

PROCEDURE FOR the PRODUCTION OF 1-SUBSTITUIERTEN 2-METHYL-TETRAHYDROPYRIMIDINEN

CHIRALE DIAZAPHOSPHOLIDINLIGANDEN

Process for preparing asymmetric compound by using metal complex

USE OF AN IONIC COMPOUND, DERIVED FROM MALONONITRILE AS A PHOTOINITIATOR, RADICAL INITIATORS OR CATALYSER IN POLYMERIZATION PROCESSES OR AS A BASIC DYE

La présente invention concerne l'utilisation de composés ioniques dérivés du malononitrile comme photoinitiateur source d'acide catalyseur dans un procédé de polymérisation ou de réticulation de monomères ou de prépolymères capables de réagir par voie cationique, ou comme catalyseur dans un procédé pour la modification de polymères. L'invention vise également l'utilisation de composés ioniques dérivés du malononitrile dans les colorants cationiques. The present invention relates to the use of ionic compounds derived from malononitrile as a photoinitiator source of catalyst acid in a process for the polymerization or crosslinking of monomers or prepolymers capable of reacting cationically, or as a catalyst in a process for the modification of polymers. The invention also relates to the use of ionic compounds derived from malononitrile in cationic dyes.

USE OF AN IONIC COMPOUND, DERIVED FROM MALONONITRILE AS A PHOTOINITIATOR, RADICAL INITIATORS OR CATALYSER IN POLYMERIZATION PROCESSES OR AS A BASIC DYE

La présente invention concerne l'utilisation de composés ioniques dérivés du malononitrile comme photoinitiateur source d'acide catalyseur dans un procédé de polymérisation ou de réticulation de monomères ou de prépolymères capables de réagir par voie cationique, ou comme catalyseur dans un procédé pour la modification de polymères. L'invention vise également l'utilisation de composés ioniques dérivés du malononitrile dans les colorants cationiques.

HETEROGENEOUS CATALYTIC SYSTEM AND ITS USE.

METHOD OF PREPARATION OF 2-METHYLTETRAHYDROPYRIMIDINES 1-SUBSTITUEES

NEW DIPHOSPHINES, THEIR COMPLEXES WITH METALS OF TRANSITION AND LEURUTILISATION IN ASYMMETRICAL SYNTHESIS

The invention relates to novel diphosphines, in optically pure or racemic form, of formula (I):in which:R1 and R2 are a (C5-C7)cycloalkyl group, an optionally substituted phenyl group or a 5-membered heteroaryl group; andA is (CH2-CH2) or CF2.The invention further relates to the use of a compound of formula (I) as a ligand for the preparation of a metal complex useful as a chiral catalyst in asymmetric catalysis, and to the chiral metal catalysts comprising at least one ligand of formula (I).

ENANTIOSELECTIVE PHOSPHORAMIDITE COMPOUNDS AND CATALYSTS

This invention relates to phosphoramidite compounds and catalyst complexes which can be used to provide enantioselective reactions including hydroamination reactions, etherification reactions and conjugate addition reactions and allylic substitution reactions, among others. In a first aspect, the present invention is directed to phosphoramidite and related compounds according to general structure (I), where Z is absent or is a group containing O, N or S, preferably O; R1 and R2 are independently an optionally substituted C1-12 alkyl group, an optionally substituted (CH2)n-aromatic group or (CH2)n-heteroaromatic group, or are linked together to form an optionally substituted aliphatic or (CH2)n-aromatic dianion of a diol, diamine, dithiol, aminoalcohol, aminohiolate or a alcoholthiol group; R3’ and R3 are each independently H, an optionally substituted C1-C12 alkyl group or an optionally substituted (CH2)n-aromatic group with the proviso that R3’ and R3 are not both H, or together ...

COORDINATION COMPLEX SYSTEM COMPRISING BUILDING BLOCKS AND USE THEREOF AS A CATALYST

The invention relates to a coordination complex system comprising a ligand having at least two donor moieties, which are complexed to at least a metal selected from a transition metal and lanthanide, characterized in that the ligand comprises at least two building blocks, each having at least one functional group and at least one donor moiety, wherein one building block is non-covalently bonded through its functional group to a complementary functional group of another building block or of a template, wherein the template comprises at least one other functional group that is noncovalently bonded to a complementary functional group of another building block, and wherein all building blockemplate-building block structures are the same when the template contains more than two functional groups.

CYCLO-ALIPHATIC-AROMATIC DIPHOSPHINE AND YOUR USE IN THE CATALYSIS

NEW DIPHOSPHINE, THEIR COMPLEXES WITH TRANSITION METALS AND THEIR USE IN THE ASYMMETRICAL SYNTHESIS

VERFAHREN ZUR HERSTELLUNG VON 1-SUBSTITUIERTEN 2-METHYL-TETRAHYDROPYRIMIDINEN

PROCEDURE FOR THE PRODUCTION OF AN ASYMMETRICAL CONNECTION USING A METAL COMPLEX

NOVEL DIPHOSPHINES, THEIR COMPLEXES WITH TRANSITION METALS AND THEIR USEIN ASYMMETRIC SYNTHESIS

The invention relates to novel diphosphines, in optically pure or racemic form, of formula (I): (see formula I) in which: - R1and R2 are a(C5-C7)cycloalkyl group, an optionally substituted phenyl group or a 5-membered heteroaryl group; and - A is (CH2-CH2) or CF2. The invention further relates to the use of a compound of formula (I) as a ligand for the preparation of a metal complex useful as a chiral catalyst in asymmetric catalysis, and to the chiral metal catalysts comprising at least one ligand of formula (I).

WEAKLY COORDINATING ANIONS CONTAINING POLYFLUOROALKOXIDE LIGANDS

A compound comprising a polyfluorinated anion and the use thereof is provided. Specifically, the present invention provides a compound comprising an anion which comprises a polyfluorinated alkoxide coordinated to a transition metal, or a Group III, IV or V element.

PROCEDURE FOR the PRODUCTION OF 1-SUBSTITUIERTEN 2-METHYL-TETRAHYDROPYRIMIDINEN

Weakly coordinating anions containing polyfluoroalkoxide ligands

CHEMICAL TRANSFORMATION OF SUBSTRATES USING NONMETALLIC, ORGANIC CATALYST COMPOSITIONS

A method is provided for catalytically transforming a functional group within a first reactant by reaction with a second reactant in the presence of a nonmetallic, organic catalyst composition composed of a heteroatom-containing activator and an acid, or a salt of a heteroatom-containing activator and an acid. Exemplary first reactants are .alpha.,.beta.-unsaturated carbonyl compounds such as .alpha.,.beta.-unsaturated ketones and .alpha.,.beta.- unsaturated aldehydes. The heteroatom of the activator is a Group 15 or Group 16 element such as nitrogen, oxygen, sulfur or phosphorus, and exemplary heteroatom-containing activators are amines. Chiral heteroatom-containing activators can be used to catalyze enantioselective reactions, such that a chiral product is obtained from a chiral or achiral starting material in enantiomerically pure form.

HETEROGENEOUS CATALYTIC SYSTEM AND ITS USE.

La présente invention concerne un système catalytique hétérogène comprenant :- un polymère organique, apte à former une phase gel en présence d'un solvant,- un liquide ionique lié audit polymère par interaction covalente entre ledit polymère et au moins une des deux entités ioniques constituant ledit liquide ionique, et- au moins une espèce catalytique ou précatalytique immobilisée en tout partie dans le système catalytique hétérogène par interaction non covalente avec au moins une des entités ioniques constituant ledit liquide ionique. The present invention relates to a heterogeneous catalytic system comprising: an organic polymer, capable of forming a gel phase in the presence of a solvent, an ionic liquid bonded to said polymer by covalent interaction between said polymer and at least one of the two ionic entities constituting said ionic liquid, and- at least one catalytic or precatalytic species immobilized in any part in the heterogeneous catalytic system by non-covalent interaction with at least one of the ionic entities constituting said ionic liquid.

BASE STABLE IONIC LIQUIDS

The present invention relates to novel base stable ionic liquids and uses thereof as solvents in chemical reactions, especially base catalysed chemical reactions and reactions comprising the use of strong basis.

CHIRAL POROUS METAL PHOSPHONATES FOR HETEROGENEOUS ASYMMETRIC CATALYSIS

Chiral porous zirconium phosphonates containing metal complex moieties are provided, synthesized via a molecular building block approach, and characterized by a variety of techniques including TGA, adsorption isotherms, XRD, SEM, IR, and microanalysis. These hybrid solids may be used for enantioselective heterogeneous asymmetric hydrogenation of aromatic ketones with remarkably high e.e. values of up to 99.2%. Similarly prepared chiral porous solids may be used for asymmetric hydrogenation of -keto esters with e.e.'s of up to 95%. The solid catalysts can also be easily recycled and reused multiple times without the loss of activity and enantioselectivity. Ready tunability of such a molecular building block approach allows the optimization of these hybrid materials to provide practically useful heterogeneous asymmetric catalysts.

Polymer-supported arylbis(perfluoroalkylsulfonyl)-methane

The present invention provides a solid acid catalyst that is excellent from the point of toxicity, environment and others, wherein reaction can be progressed effectively with Bronsted acid or Lewis acid catalyst. For example, the benzoylation reaction of alcohol can also be progressed easily, and further, the catalyst can be recovered and recycled easily. The para position of arylbis(perfluoroalkylsulfonyl)methane represented by the general formula [1] (wherein R1 shows a substituted or unsubstituted aryl group, Rf1 and Rf2 are independent to each other and show a perfluoroalkyl group), a pentafluorophenylbis(perfluoroalkylsulfonyl)methane, for example, is supported on a polystyrene resin, and a polystyrene-supported arylbis(perfluoroalkylsulfonyl)methane represented by the general formula [3] (wherein R3 shows a substituted or unsubstituted arylene group, Rf1 and Rf2 are the same as described above) is obtained.

Pentacyclic anion salts or tetrazapentalene derivatives and their uses as ionic conducting materials

The invention relates to ionic compounds in which the anionic load has been delocalized. A compound disclosed by the invention includes an anionic portion combined with at least one cationic portion M m+ in sufficient numbers to ensure overall electronic neutrality; the compound is further comprised of M as a hydroxonium, a nitrosonium NO + , an ammonium —NH 4 + , a metallic cation with the valence m, an organic cation with the valence m, or an organometallic cation with the valence m. The anionic load is carried by a pentacyclical nucleus of tetrazapentalene derivative bearing electroattractive substituents. The compounds can be used notably for ionic conducting materials, electronic conducting materials, colorant, and the catalysis of various chemical reactions.

Salts of heterocyclic anions and their uses as ionic conductive materials

Salts of heterocyclic anions Ionic compounds comprising an anionic part in association with cationic part(s) M+m in a number sufficient to provide electronic neutrality to the compound, M = hydroxonium, nitronium NO+, ammonium -NH4+, a metallic cation with a valency m, an organic cation with a valency m, or an organometallic cation having a valency m, and the anionic part is an aromatic heterocycle of formula (I) or (II): Y1-Y5 = carbonyl, sulphonyl, thiocarbonyl, thionyl, -C(=NCN)- or -C(=C(CN)2)- groups; Z = an electron-attracting group having a Hammett parameter at least equal to that of a fluorine atom; and Ra - Rd = monovalent or divalent organic radical or form part of a polymer chain, with the proviso that Rc and/or Rd is a perfluorinated radical.

NEUE DIPHOSPHINE, DEREN KOMPLEXE MIT ÜBERGANGSMETALLEN UND DEREN VERWENDUNG IN DER ASYMMETRISCHEN SYNTHESE

Catalyst

A process for the addition of a nucleophile, such as oxygen provided by a peroxide group or sulphur provided by a -SPh group, across an electron poor carbon-carbon double bond (a Michael addition), such as an enone group. The addition reaction, carried out in a solvent, is characterised by use of a catalyst comprising a soluble polymer, such as PEG (polyethylene glycol) and a polyamino acid, such as leucine, alanine, neopentyglycine.

Basic ionic liquids

PROCESS FOR THE PREPARATION OF 1-SUBSTITUTED 2-METHYL-TETRAHYDROPYRIMIDINES

ENANTIOSELECTIVE PHOSPHORAMIDITE COMPOUNDS AND CATALYSTS

This invention relates to phosphoramidite compounds and catalyst complexes which can be used to provide enantioselective reactions including hydroamination reactions, etherification reactions and conjugate addition reactions and allylic substitution reactions, among others. In a first aspect, the present invention is directed to phosphoramidite and related compounds according to general structure (I), where Z is absent or is a group containing O, N or S, preferably O; R1 and R2 are independently an optionally substituted C1-12 alkyl group, an optionally substituted (CH2)n-aromatic group or (CH2)n- heteroaromatic group, or are linked together to form an optionally substituted aliphatic or (CH2)n-aromatic dianion of a diol, diamine, dithiol, aminoalcohol, aminohiolate or a alcoholthiol group; R3~ and R3 are each independently H, an optionally substituted C1-C12 alkyl group or an optionally substituted (CH2)n-aromatic group with the proviso that R3~ and R3 are not both H, or together R3~ and ...

MIXTURES OF CHIRAL MONOPHOSPHORUS COMPOUNDS USED AS LIGAND SYSTEMS FOR ASYMMETRIC TRANSITION METAL CATALYSIS

The invention relates to certain chiral transition metal catalysts, to the metal of which at least two structurally different monophosphorus ligands are bonded, at least one of said monophosphorus ligands being chiral. Said chiral transition metal catalysts are suitable as catalysts for use in asymmetric transition metal-catalyzed reactions, providing better enantioselectivities than in cases where only one structurally defined ligand is used.

MALONONITRILE-DERIVATIVE ANION SALTS, AND THEIR USES AS IONIC CONDUCTING MATERIALS

La présente invention concerne l'utilisation de composés ioniques dérivés du malononitrile comme photoinitiateur source d'acide catalyseur dans un procédé de polymérisation ou de réticulation de monomères ou de prépolymères capables de réagir par voie cationique, ou comme catalyseur dans un procédé pour la modification de polymères. L'invention vise également l'utilisation de composés ioniques dérivés du malononitrile dans les colorants cationiques.

PERFLUORINATED AMIDE SALTS AND THEIR USES AS IONIC CONDUCTING MATERIALS

L'invention concerne des composés ioniques dans lesquels la charge anionique est délocalisée. Un composé de l'invention est constitué par une amide ou l'un de ses sels, comprenant une partie anionique associée à au moins une partie cationique M+m en nombre suffisant pour assurer la neutralité électronique de l'ensemble. M est un hydroxonium, un nitrosonium NO+, un ammonium -NH4+, un cation métallique ayant la valence m, un cation organique ayant la valence m ou un cation organo-métallique ayant la valence m. La partie anionique répond à la formule RF-SOx-N-Z dans laquelle RF est un groupe perfluoré, x est 1 ou 2, et Z est un substituant électroattracteur. Les composés sont utiles notamment pour les matériaux à conduction ionique, les matériaux à conduction électronique, les colorants et la catalyse de diverses réactions chimiques.

PERFLUORINATED AMIDE SALTS AND THEIR USES AS IONIC CONDUCTING MATERIALS

L'invention concerne des composés ioniques dans lesquels la charge anionique est délocalisée. Un composé de l'invention est constitué par une amide ou l'un de ses sels, comprenant une partie anionique associée à au moins une partie cationique M+m en nombre suffisant pour assurer la neutralité électronique de l'ensemble. M est un hydroxonium, un nitrosonium NO+, un ammonium -NH4+, un cation métallique ayant la valence m, un cation organique ayant la valence m ou un cation organo-métallique ayant la valence m. La partie anionique répond à la formule RF-SOx-N-Z dans laquelle RF est un groupe perfluoré, x est 1 ou 2, et Z est un substituant électroattracteur. Les composés sont utiles notamment pour les matériaux à conduction ionique, les matériaux à conduction électronique, les colorants et la catalyse de diverses réactions chimiques.

Basic ionic liquids

新型二膦及其与过渡金属形成的络合物以及该类络合物在不对称合成中的应用

... 本发明涉及外消旋型或光学纯型的式(I)新型二膦衍生物，其中：R#-[1]与R#-[2]为(C#-[5]-C#-[7])环烷基、选择性地具有取代基的苯基或5元杂芳基；而且A为(CH#-[2]-CH#-[2])或CF#-[2]。本发明还涉及式(I)化合物在制备金属络合物时作为配体的用途以及含有至少一个式(I)配体的手性金属催化剂，所述金属络合物可用作不对称性催化中的手性催化剂。 ...

METHOD OF PREPARATION OF 2-METHYLTETRAHYDROPYRIMIDINES 1-SUBSTITUEES

PROTON CONDUCTOR IN LIQUID FORM

Disclosed is a proton conductor in liquid form, comprised of a mixture of the following components: (a) a salt combined with a nitrogenated base along with an acid, according to formula (I), wherein Z1, Z2, Z3, and Z4, whether identical or different, represent a group -N= or -C(Zi)=, wherein Zi represents a hydrogen atom, a linear or branched alkyl radical with from 1 to 20 carbon atoms, a fluoroalkyl radical with from 1 to 20 carbon atoms, or an oxoalkyl or azaalkyl radical with from 1 to 20 carbon atoms, as long as at least one and at most two of the groups Z1, Z2, Z3, and Z4 represent -N=; two adjacent carbon atoms are possibly hydrogenated; the nitrogenated base possibly forms part of a polymeric matrix; and X- represents an anion derivative of an acid selected from the group formed by the sulphonic acids of the formula RFSO3H, the sulphonimides of the formula (RFSO2) (R'FSO2)NH and the methylures of the formula (RFSO2) (R'FSO2)CH2 or (RFSO2) (R'FSO2) (R"FSO2)CH, wherein RF, R'F or ...

IONIC LIQUIDS WITH A CATION COMPRISING A BASIC MOIETY

POLYMER SUPPORT TYPE ARYLBIS(PERFLUOROALKYLSULFONYL) METHANE

PROBLEM TO BE SOLVED: To provide a solid acid catalyst which can improve the efficiency of a reaction proceeding in the presence of a Broensted acid or a Lewis acid catalyst, for example, facilitates the benzoylation of an alcohol, can easily be recovered or recycled, and is excellent from the viewpoints of toxicity, environments and the like. SOLUTION: This polystyrene support type arylbis(perfluoroalkylsulfonyl) methane represented by general formula [3] (R3 is a substituted or non- substituted arylene; Rf1 and Rf2 are each independently a perfluoroalkyl) is obtained by supporting the para-position of an arylbis(perfluoroalkylsulfonyl) methane represented by general formula [1] (R1 is a substituted or non- substituted aryl), such as pentafluorophenylbis(perfluoroalkylsulfonyl)methane, with polystyrene resin. COPYRIGHT: (C)2003,JPO ...

PROCESS FOR THE PREPARATION OF 1-SUBSTITUTED 2-METHYL-TETRA HYDROPYRIMIDINES

... 1464829 1 - Substituted - 2 - methyl - tetrahydropyrimidines BAYER AG 15 Aug 1975 [17 Aug 1974] 34076/75 Heading C2C A process for preparing a 1-substituted-2- methyl-tetrahydropyrimidine comprises reacting an N-substituted propylene diamine with an acetoacetic acid ester or amide at a temperature of from 0‹ to 80‹ C. and removing the water produced in the reaction at a temperature of from 0 to 80‹ C. The process is preferably carried out in the presence of an inert solvent. The water of reaction may be removed by distillation or by addition of an inert dehydrating agent.

PROTON CONDUCTOR IN LIQUID FORM

L'invention concerne un conducteur protonique sous forme liquide, constitué d'un mélange des composants suivants: (a) un sel d'addition d'une base azotée avec un acide, répondant à la formule: (I) dans laquelle Z1, Z2, Z3 et Z4, identiques ou différents, représentent un groupement -N= ou -C(Zi)= dans lequel Zi désigne un atome d'hydrogène, un radical alkyle linéaire ou ramifié ayant de 1 à 20 atomes de carbone, un radical fluoroalkyle ayant de 1 à 20 atomes de carbone, ou un radical oxoalkyle ou azaalkyle ayant de 1 à 20 atomes de carbone, sous réserve qu'au moins un et au plus deux des groupements Z1, Z2, Z3 et Z4 représentent -N=, deux atomes de carbone adjacents étant éventuellement hydrogénés et la base azotée faisant éventuellement partie d'une trame polymérique, et X- représente un anion dérivé d'un acide choisi dans le groupe constitué par les acides sulfoniques de formule RFSO3H, les sulfonimides de formule (RFSO2) (R'FSO2)NH et les méthylures de formule (RFSO2) (R'FSO2)CH2 ou (RFSO2) (R'FSO2) (R"FSO2)CH, dans lesquelles RF, R'F ou R"F représente indépendamment un radical F(CF2)n-, n étant compris entre 0 et 6, l'acide faisant éventuellement partie d'une trame polymérique; et (b) une base azotée répondant à la formule (II) dans laquelle Z1, Z2, Z3 et Z4 ont les significations précitées, la base azotée faisant éventuellement partie d'une trame polymérique; les composants (a) et (b) étant présents dans des proportions telles à former une composition ayant un point de fusion inférieur à 25 ~C. Le conducteur protonique selon l'invention est utile comme électrolyte liquide, gel ou polymère dans divers systèmes électrochimiques. The invention relates to a proton conductor in liquid form, consisting of a mixture of the following components: (a) an addition salt of a nitrogenous base with an acid, corresponding to the formula: (I) in which Z1, Z2 , Z3 and Z4, identical or different, represent a ...

HETEROCYCLIC AROMATIC ANION SALTS, AND THEIR USES AS IONIC CONDUCTING MATERIALS

L'invention a pour objet des composés ioniques, dans lesquels la charge anionique est délocalisée, et leurs utilisations. Un composé de l'invention comprend une partie anionique associée à au moins une partie cationique M+m en nombre suffisant pour assurer la neutralité électronique de l'ensemble. La partie anionique est constituée par l'un des groupes (A) et (B) dans lesquels Y1, Y2, Y3, Y4 et Y5 représentent un groupement carbonyle, un groupement sulfonyle, un groupe thiocarbonyle, un groupement thionyle, un groupement C(=NCN)- ou un groupement -C(=C(CN)2)-; Z représente un radical électroattracteur; chacun des substituants RA, RB, RC et RD représentent indépendamment des autres un radical organique monovalent ou divalent, ou fait partie d'une chaîne polymère, l'un au moins des substituants RC et RD étant un radical perfluoré. Les composés sont utiles notamment pour les matériaux à conduction ionique, les matériaux à conduction électronique, les colorants et la catalyse de diverses réactions chimiques. The subject of the invention is ionic compounds, in which the anionic charge is delocalized, and their uses. A compound of the invention comprises an anionic part associated with at least one cationic part M + m in sufficient number to ensure the electronic neutrality of the whole. The anionic part is constituted by one of the groups (A) and (B) in which Y1, Y2, Y3, Y4 and Y5 represent a carbonyl group, a sulfonyl group, a thiocarbonyl group, a thionyl group, a group C ( = NCN) - or a group -C (= C (CN) 2) -; Z represents an electron-withdrawing radical; each of the substituents RA, RB, RC and RD independently represent the others a monovalent or divalent organic radical, or is part of a polymer chain, at least one of the substituents RC and RD being a perfluorinated radical. The compounds are useful in particular for ionically conductive materials, electronically conductive materials, dyes and the catalysis of various chemical reactions.

Catalyst for asymmetric synthesis, ligand used therefor and method for producing optically active compound by asymmetric synthetic reaction using the same

BASE STABLE IONIC LIQUIDS

The present invention relates to novel base stable ionic liquids and uses thereof as solvents in chemical reactions, especially base catalysed chemical reactions and reactions comprising the use of strong basis.

PERFLUORINATED AMIDE SALTS AND THEIR USES AS IONIC CONDUCTING MATERIALS

The invention relates to ionic compounds in which the anionic load has been delocalized. A compound disclosed by the invention is comprised of an amide or one of its salts, including an anionic portion combined with at least one cationic portion M+m in sufficient numbers to ensure overall electronic neutrality; the compound is further comprised of M as a hydroxonium, a nitrosonium NO+, an ammonium -NH4+, a metallic cation with the valence m, an organic cation with the valence m, or an organometallic cation with the valence m. The anionic portion matches the formula Rf-SOx-N-Z, wherein Rf is a perfluorinated group, x is 1 or 2, and Z is an electroattractive substituent. The compounds can be used notably for ionic conducting materials, electronic conducting materials, colorants, and the catalysis of various chemical reactions.

Catalyst comprising N-substituted cyclic imide compound and process for producing organic compound using the catalyst

A catalyst of the invention includes an imide compound having a N-substituted cyclic imide skeleton represented by following Formula (I): wherein R is a hydroxyl-protecting group. Preferred R is a hydrolyzable protecting group. R may be a group obtained from an acid by eliminating an OH group therefrom. Such acids include, for example, carboxylic acids, sulfonic acids, carbonic acid, carbamic acid, sulfuric acid, nitric acid, phosphoric acids and boric acids. The catalyst may include the imide compound and a metallic compound in combination. In the presence of the catalyst, (A) a compound capable of forming a radical is allowed to react with (B) a radical scavenging compound and thereby yields an addition or substitution reaction product of the compound (A) and the compound (B) or a derivative thereof. This catalyst can produce an organic compound with a high selectivity in a high yield as a result of, for example, an addition or substitution reaction under mild conditions.

Base Stable Ionic Liquids

The present invention relates to novel base stable ionic liquids and uses thereof as solvents in chemical reactions, especially base catalysed chemical reactions and reactions comprising the use of strong basis.

Ionic malonitril derivatives and their uses

FLÜSSIGER PROTONENLEITER

Verfahren zur Herstellung von optisch aktiven Verbindungen

MALONONITRILE-DERIVATIVE ANION SALTS, AND THEIR USES AS IONIC CONDUCTING MATERIALS

L'invention a pour objet des composés ioniques dérivés du malononitrile dans lesquels la charge anionique est délocalisée. Un composé ionique de l'invention comprend une partie anionique associée à au moins une partie cationique Mm+ en nombre suffisant pour assurer la neutralité électronique de l'ensemble. Il est caractérisé en ce que M est un hydroxonium, un nitrosonium NO+, un ammonium -NH4+, un cation métallique ayant la valence m, un cation organique ayant la valence m ou un cation organométallique ayant la valence m, et que la partie anionique répond à l'une des formules RD-Y-C(CN)2- ou Z-C(CN)2- dans lesquelles Z est un groupe électroattracteur, RD est un radical organique et Y est un carbonyle, un thiocarbonyle, un sulfonyle, un sulfinyle ou un phosphonyle. Les composés sont utiles notamment pour les matériaux à conduction ionique, les matériaux à conduction électronique, les colorants et la catalyse de diverses réactions chimiques.

PROTON CONDUCTOR IN LIQUID FORM

L'invention concerne un conducteur protonique sous forme liquide, constitué d'un mélange des composants suivants: (a) un sel d'addition d'une base azotée avec un acide, répondant à la formule: (I) dans laquelle Z1, Z2, Z3 et Z4, identiques ou différents, représentent un groupement -N- ou -C(Z i)- dans lequel Z i désigne un atome d'hydrogène, un radical alkyle linéaire ou ramifié ayant de 1 à 20 atomes de carbone, un radical fluoroalkyle ayant de 1 à 20 atomes de carbone , ou un radical oxoalkyle ou azaalkyle ayant de 1 à 20 atomes de carbone, sous réserve qu'au moins un et au plus deux des groupemen ts Z1, Z2, Z3 et Z4 représentent -N-, deux atomes de carbone adjacents étant éventuellement hydrogénés et la base azotée faisant éventuellement partie d'une trame polymérique, et X- représente un anion dérivé d'un acide choisi dans le groupe constitué par les acides sulfoniques de formule RFSO3H, les sulfonimides de formule (R F SO2) (R'F SO2)NH et les méthylures de formule (R F SO2) (R'F SO2 ...

SURFACE MODIFIED CARBONATE MATERIALS

<IMG> Greffage d'un polymère à la surface d'un matériau carboné comportant des fonctions carboxyles, amines et/ou hydroxyles à sa surface. On met ce matériau en suspension dans une solution comprenant le polymère à greffer, lequel comporte une fonction carboxyle, amine et/ou hydroxyle, la solution comprenant aussi un solvant du polymère. On effectue ensuite un traitement provoquant la déshydratation en une fonction carboxyle, d'une fonction amine et/ou hydroxyle et l'on greffe ainsi le polymère sur le matériau carboné par des liens esters ou amides. Utilisation dans la cathode ou l'anode d'un générateur électrochimique, dans un matériau polymère peu polaire, dans une encre, et comme dépôt conducteur sur un plastique flexible utilisé comme contact électrique, comme protection électromagnétique ou comme protection antistatique.

PENTACYCLIC ANION SALTS OR TETRAZAPENTALENE DERIVATIVES AND THEIR USES AS IONIC CONDUCTING MATERIALS

L'invention concerne des composés ioniques dans lesquels la charge anionique est délocalisée. Un composé de l'invention comprend une partie anionique associée à au moins une partie cationique M m+ en nombre suffisant pour assurer la neutralité électronique de l'ensemble. M est un hydroxonium, un nitrosonium NO+, un ammonium -NH4+, un cation métallique ayant la valence m, un cation organique ayant la valence m, un cation organo-métallique ayant la valence m. La charge anionique est portée par un noyau pentacyclique ou dérivé de tétrazapentalène portant des substituants électroattracteurs. Les composés sont utiles notamment pour les matériaux à conduction ionique, les matériaux à conduction électronique, les colorants et la catalyse de diverses réactions chimiques.

POLYMER-SUPPORTED TRANSITION METAL CATALYST COMPLEXES AND METHODS OF USE

A catalyst composition comprising a polymer functionalized with a ligand for binding a transition metal containing compound to form a transition metal complex, wherein said functionalized polymer has a number average molecular weight of about 5,000 to 30,000 g/ mol and a polydispersity index of about 1.0 to 2,0, The catalyst is used in a hydroformylation reaction, preferably one in which the liquid phase has bee~ voIumetrically expanded with a compressed gas, is readily recyclable using nanofiltratïon.

NEW DIPHOSPHINES, THEIR COMPLEXES WITH METALS OF TRANSITION AND THEIR USE IN ASYMMETRICAL SYNTHESIS

The invention concerns novel optically pure or racemic diphosphines of formula (I), wherein: R<sb>1</sb> and R<sb>2</sb> represent a C<sb>5</sb>-C<sb>7</sb> cycloalkyl group, an optionally substituted phenyl group or a five-membered heteroaryl group; A represents (CH<sb>2</sb>-CH<sb>2</sb>) or CF<sb>2</sb>. The invention also concerns the use of a compound of formula (1) as ligand for preparing a metal complex, useful as chiral catalyst in asymmetric catalysis, and chiral metal catalysts comprising at least a ligand of formula (I).

BASIC CATALYSTS AND PROCESS FOR PRODUCING CARBONYL COMPOUND DERIVATIVES

Basic catalysts are prepared from at least one alkali metal compound selected from the group consisting of alkali metal alkoxides, hydroxides and oxides and an alkaline earth metal oxide in a weight ratio of the alkali metal compound to the alkaline earth metal oxide in the range of 0.005/1 to 1/1, and are used for the reaction of aldehydes to form glycol monoesters. Thus, highly active, efficient basic catalysts usable for the aldol reaction or the like to give intended products with a high selectivity are provided.

Chiral phosphorus cyclic compounds for transition metal-catalyzed asymmetric reactions

Chiral phospholanes having biaryl chirality for applications in asymmetric catalysis are provided. A series of new chiral mono- or bidentate phosphorus ligands were efficiently prepared through a key intermediate (S)-4-chloro-4,5-dihydro-3H-4-phospha-cyclohepta[2,1-a;3,4-a′]binaphthalene and its derivatives. These ligands were complexed with transition metals to prepare catalysts, which were used in asymmetric catalytic reactions, such as, asymmetric hydrogenation, hydride transfer, allylic alkylation, hydrosilylation, hydroboration, hydrovinylation, hydroformylation, olefin metathesis, hydrocarboxylation, isomerization, cyclopropanation, Diels-Alder reaction, Heck reaction, isomerization, Aldol reaction, Michael addition; epoxidation, kinetic resolution or [m+n] cycloaddition wherein m=3 to 6 and n=2.

Asymmetric catalysis based on chiral phospholanes and hydroxyl phospholanes

Chiral phosphine ligands derived from chiral natural products including D-mannitol and tartaric acid. The ligands contain one or more 5-membered phospholane rings with multiple chiral centers, and provide high stereoselectivity in asymmetric reactions.

Phase selective polymer supports for catalysis

Phase-selective soluble polymer supports for catalysts are described. The catalysts utilize polystyrene copolymers having enhanced solubility in nonpolar solvents. Other catalysts of the invention utilize polyisobutylene supports. Methods of catalyzing chemical reactions using latent biphasic solvents are also disclosed.

CHIRALE DIAZAPHOSPHOLIDINLIGANDEN

CATALYST FOR ASYMMETRIC SYNTHESIS, LIGAND FOR USE THEREIN, AND PROCESS FOR PRODUCING OPTICALLY ACTIVE COMPOUND THROUGH ASYMMETRIC SYNTHESIS REACTION USING THEM

Compounds of the following general formula (1a) or (1b). (1a) (1b) Further, there are provided a complex comprising a central metal of rhodium and any of compounds of the general formula (1a) or (1b) as a ligand; comprised of this complex, a catalyst for optically active .beta.-substituted carbonyl compound synthesis and catalyst for asymmetric 1,2 addition reaction; using these catalysts, a process for producing an optically active .beta.-aryl compound from an .alpha.,.beta.-unsaturated compound and an arylboronic acid derivative and process for producing an optically active aryl alcohol compound from an aldehyde compound and an aryl boronic acid derivative; a complex comprising a central metal of palladium and any of compounds of the general formula (1a) or (1b) as a ligand; comprised of this complex, a catalyst for asymmetric allyl- position substitution reaction; and using this catalyst, a process for producing an optically active dialkyl (1,3-disubstituted propenyl)malonate compound ...

NOVEL DISPHOSPINES, THEIR COMPLEXES WITH TRANSITION METALS AND THEIR USE IN ASYMMETRIC SYNTHESIS

L'invention concerne de nouvelles disphosphines de formule (I) sous forme optiquement pure ou racémique, formule (I), dans laquelle: R1 et R2 représentent un groupe (C5-C7)cycloalkyle, un groupe phényle éventuellement substitué ou un groupe hétéroaryle à 5 chaînons; A représente (CH2-CH2) ou CF2. L'invention concerne également l'utilisation d'un composé de formule (I) comme ligand pour la préparation d'un complexe métallique, utile comme catalyseur chiral dans la catalyse asymétrique, ainsi que les catalyseurs métalliques chiraux comprenant au moins un ligand de formule (I).

PENTACYCLIC ANION SALTS OR TETRAZAPENTALENE DERIVATIVES AND THEIR USES AS IONIC CONDUCTING MATERIALS

L'invention concerne des composés ioniques dans lesquels la charge anionique est délocalisée. Un composé de l'invention comprend une partie anionique associée à au moins une partie cationique M m+ en nombre suffisant pour assurer la neutralité électronique de l'ensemble. M est un hydroxonium, un nitrosonium NO+, un ammonium -NH4+, un cation métallique ayant la valence m, un cation organique ayant la valence m, un cation organo-métallique ayant la valence m. La charge anionique est portée par un noyau pentacyclique ou dérivé de tétrazapentalène portant des substituants électroattracteurs. Les composés sont utiles notamment pour les matériaux à conduction ionique, les matériaux à conduction électronique, les colorants et la catalyse de diverses réactions chimiques. The invention relates to ionic compounds in which the anionic charge is delocalized. A compound of the invention comprises an anionic part associated with at least one cationic part M m + in sufficient number to ensure the electronic neutrality of the whole. M is a hydroxonium, a nitrosonium NO +, an ammonium -NH4 +, a metal cation having the valence m, an organic cation having the valence m, an organometallic cation having the valence m. The anionic charge is carried by a pentacyclic ring or derivative of tetrazapentalene carrying electron-withdrawing substituents. The compounds are useful in particular for ionically conductive materials, electronically conductive materials, dyes and the catalysis of various chemical reactions.

POLYMER-SUPPORTED TRANSITION METAL CATALYST COMPLEXES AND METHODS OF USE

A catalyst composition comprising a polymer functionalized with a ligand for binding a transition metal containing compound to form a transition metal complex, wherein said functionalized polymer has a number average molecular weight of about 5,000 to 30,000 g/ mol and a polydispersity index of about 1.0 to 2,0, The catalyst is used in a hydroformylation reaction, preferably one in which the liquid phase has bee» voIumetrically expanded with a compressed gas, is readily recyclable using nanofiltrat?on.

PENTACYCLIC ANION SALTS OR TETRAZAPENTALENE DERIVATIVES AND THEIR USES AS IONIC CONDUCTING MATERIALS

L'invention concerne des composés ioniques dans lesquels la charge anionique est délocalisée. Un composé de l'invention comprend une partie anionique associée à au moins une partie cationique M m+ en nombre suffisant pour assurer la neutralité électronique de l'ensemble. M est un hydroxonium, un nitrosonium NO+, un ammonium -NH4+, un cation métallique ayant la valence m, un cation organique ayant la valence m, un cation organo-métallique ayant la valence m. La charge anionique est portée par un noyau pentacyclique ou dérivé de tétrazapentalène portant des substituants électroattracteurs. Les composés sont utiles notamment pour les matériaux à conduction ionique, les matériaux à conduction électronique, les colorants et la catalyse de diverses réactions chimiques.

COORDINATION COMPLEX SYSTEM COMPRISING BUILDING BLOCKS AND USE THEREOF AS A CATALYST

The invention relates to a coordination complex system comprising a ligand having at least two donor moieties, which are complexed to at least a metal selected from a transition metal and lanthanide, characterized in that the ligand comprises at least two building blocks, each having at least one functional group and at least one donor moiety, wherein one building block is non-covalently bonded through its functional group to a complementary functional group of another building block or of a template, wherein the template comprises at least one other functional group that is noncovalently bonded to a complementary functional group of another building block, and wherein all building blockemplate-building block structures are the same when the template contains more than two functional groups. © KIPO & WIPO 2007 ...

SETT ATT FRAMSTELLA 1-SUBSTITUERADE 2-METYL-TETRAHYDROPYRIMIDINER.

HETEROCYCLIC AROMATIC ANION SALTS, AND THEIR USES AS IONIC CONDUCTING MATERIALS

The invention relates to ionic compounds in which the anionic load has been displaced, and the uses of these compounds. A compound disclosed by the invention comprises an anionic portion combined with at least one cationic portion M+m in sufficient numbers to ensure overall electronic neutrality. The anionic portion is comprised of one of the groups (A) and (B) wherein Y1, Y2, Y3, Y4, and Y5 represent a carbonyl group, a sulphonyl group, a thiocarbonyl group, a thionyl group, a -C(=NCN)- group or a -C(=C(CN)2)- group; Z represents an electroattractive radical; each of the substituents, RA, RB, RC, and RD represents independently of one another a monovalent or divalent organic radical or is part of a polymer chain, with at least one or the substituents RC and RD being a perfluorinated radical. The compounds can be used especially for ionic conducting materials, electronic conducting materials, colorants, and the catalysis of various chemical reactions.

Pentacyclic anion salts or tetrazapentalene derivatives and their uses as ionic conducting materials

The invention relates to ionic compounds in which the anionic load has been delocalized. A compound disclosed by the invention includes an anionic portion combined with at least one cationic portion M^m+ in sufficient numbers to ensure overall electronic neutrality; the compound is further comprised of M as a hydroxonium, a nitrosonium NO⁺, an ammonium -NH₄⁺, a metallic cation with the valence m, an organic cation with the valence m, or an organometallic cation with the valence m. The anionic load is carried by a pentacyclical nucleus of tetrazapentalene derivative bearing electroattractive substituents. The compounds can be used notably for ionic conducting materials, electronic conducting materials, colorant, and the catalysis of various chemical reactions.

CATALYSTS COMPRISING N-SUBSTITUTED CYCLIC IMIDES AND PROCESSES FOR PREPARING ORGANIC COMPOUNDS WITH THE CATALYSTS

A catalyst of the invention includes an imide compound having a N-substituted cyclic imide skeleton represented by following Formula (I): wherein R is a hydroxyl-protecting group. Preferred R is a hydrolyzable protecting group. R may be a group obtained from an acid by eliminating an OH group therefrom. Such acids include, for example, carboxylic acids, sulfonic acids, carbonic acid, carbamic acid, sulfuric acid, nitric acid, phosphoric acids and boric acids. The catalyst may include the imide compound and a metallic compound in combination. In the presence of the catalyst, (A) a compound capable of forming a radical is allowed to react with (B) a radical scavenging compound and thereby yields an addition or substitution reaction product of the compound (A) and the compound (B) or a derivative thereof. This catalyst can produce an organic compound with a high selectivity in a high yield as a result of, for example, an addition or substitution reaction under mild conditions.

11 CHIKAN 22 MECHIRUUTETORAHIDOROPIRIMIJINNOSEIZOHO

Asymmetric catalysis based on chiral phospholanes and hydroxyl phospholanes

MAIN-GROUP METAL-BASED ASYMMETRIC CATALYSTS AND APPLICATIONS THEREOF

The present invention relates to a method and catalysts for the stereoselective addition of a nucleophile to a reactive .pi.-bond of a substrate. The chiral, non-racemic catalysts of the present invention constitute the first examples of catalysts for nucleophilic additions that comprise a main-group metal and a tri- or tetra-dentate ligand.

Coordination Complex System Comprising Building Blocks and Use Thereof As a Catalyst

Asymmetric carbon-carbon-bond-forming reactions catalyzed by bifunctional cinchona alkaloids

One aspect of the present invention relates to quinine-based and quinidine-based catalysts. In certain embodiments, the quinine-based and quinidine-based catalysts contain a hydroxy group at the 6′ position. In certain embodiments, the quinine-based and quinidine-based catalysts contain an O-aryl group or an O-aroyl group at the C9 position. In certain embodiments, the quinine-based and quinidine-based catalysts contain an optionally substituted O-diazene group or an optionally substituted O-benzoyl group at the C9 position. In certain embodiments, the quinine-based and quinidine-based catalysts contain a thiourea at the C9 position. In certain embodiments, the quinine-based and quinidine-based catalysts contain an NH(═S)NH-aryl group at the C9 position. Another aspect of the present invention relates to a method of preparing a chiral, non-racemic compound from a prochiral electron-deficient alkene or prochiral imine, comprising the step of: reacting a prochiral alkene or imine with a nucleophile in the presence of a catalyst; thereby producing a chiral, non-racemic compound; wherein said catalyst is a derivatized quinine or quinidine. In certain embodiments, the nucleophile is a malonate or β-ketoester. In certain embodiments the nucleophile is an alkyl or aryl or aralkyl 2-cyano-2-alkylacetate. In certain embodiments the nucleophile is an alkyl or aryl or aralkyl 2-cyano-2-alkylacetate. Another aspect of the present invention relates to a method of kinetic resolution, comprising the step of: reacting a racemic aldehyde or racemic ketone with a nucleophile in the presence of a derivatized quinine or quinidine, thereby producing a non-racemic, chiral compound. In certain embodiments, the kinetic resolution is dynamic.

Asymmetric catalysis based on chiral phospholanes and hydroxyl phospholanes

Chiral phosphine ligands derived from chiral natural products including D-mannitol and tartaric acid. The ligands contain one or more 5-membered phospholane rings with multiple chiral centers, and provide high stereoselectivity in asymmetric reactions.

Chiral porous metal phosphonates for heterogeneous asymmetric catalysis

Chiral porous zirconium phosphonates containing metal complex moieties are provided, synthesized via a molecular building block approach, and characterized by a variety of techniques including TGA, adsorption isotherms, XRD, SEM, IR, and microanalysis. These hybrid solids may be used for enantioselective heterogeneous asymmetric hydrogenation of aromatic ketones with remarkably high e.e. values of up to 99.2%. Similarly prepared chiral porous solids may be used for asymmetric hydrogenation of beta-keto esters with e.e.'s of up to 95%. The solid catalysts can also be easily recycled and reused multiple times without the loss of activity and enantioselectivity. Ready tunability of such a molecular building block approach allows the optimization of these hybrid materials to provide practically useful heterogeneous asymmetric catalysts.

Decarboxylative conjugate additions and applications thereof

Synthetic methods are described herein operable to efficiently produce a wide variety of molecular species through conjugate additions via decarboxylative mechanisms. For example, methods of functionalization of peptide residues are described, including selective functionalization of peptide C-terminal residues. In one aspect, a method of peptide functionalization comprises providing a reaction mixture including a Michael acceptor and a peptide and coupling the Michael acceptor with the peptide via a mechanism including decarboxylation of a peptide reside.

CATALYSTS AND METHODS FOR ENANTIOSELECIVE CONJUGATE ADDITION OF AMINES TO UNSATURATED ELECTROPHILES

Disclosed are complexes and methods of using the complexes as catalysts for addition of amines to unsaturated electrophiles, as well as novel compounds produced by the disclosed complexes and methods. The disclosed methods may utilize the disclosed complexes as catalysts for adding unprotected primary amines and secondary amines to unsaturated electrophiles in an enantioselective manner to produce novel compounds which may include amino substituted succinimide compounds. 2. The complex of claim 1 , wherein R is selected from the group consisting of naphthalene claim 1 , phenanthrene claim 1 , SiPh claim 1 , and CF.3. The complex of claim 1 , wherein R is selected from the group consisting of 1-naphthalene claim 1 , 2-naphthalene claim 1 , 1-phenanthrene claim 1 , 2-phenanthrene claim 1 , and 9-phenanthrene.4. The complex of claim 1 , wherein R is 9-phenanthrene.5. The complex of claim 1 , wherein M is an alkaline earth metal.6. The complex of claim 1 , wherein M is Ca.8. The complex of claim 7 , wherein R is selected from the group consisting of naphthalene claim 7 , phenanthrene claim 7 , SiPh claim 7 , and CF.9. The complex of claim 7 , wherein R is selected from the group consisting of 1-naphthalene claim 7 , 2-naphthalene claim 7 , 1-phenanthrene claim 7 , 2-phenanthrene claim 7 , and 9-phenanthrene.10. The complex of claim 7 , wherein R is 9-phenanthrene.11. The complex of claim 7 , wherein M is an alkaline earth metal.12. The complex of claim 7 , wherein M is Ca.13. A method for conjugating an amine to an unsaturated electrophile claim 7 , the method comprising reacting the amine and the unsaturated electrophile in the presence of the complex of 1 as a catalyst in a reaction mixture claim 7 , the method optionally including recycling the complex for a subsequent reaction claim 7 , optionally wherein the amine is unprotected.14. A method for conjugating an amine to an unsaturated electrophile claim 7 , the method comprising reacting the amine and the ...

AIR-STABLE Ni(0)-OLEFIN COMPLEXES AND THEIR USE AS CATALYSTS OR PRECATALYSTS

The present invention relates to air stable, binary Ni(0)-olefin complexes and their use in organic synthesis. 2. An air-stable Ni(R)—complex according to claim 1 ,wherein Ni represents Ni(0),wherein R is the same or different and represents a trans-stilbene of the Formula (I);{'sup': 1', '5', '6', '10', '1', '10', '11', '12, 'sub': 1', '8', '3', '6', '1', '8', '3', '6', '1', '8', '3', '6, 'wherein in Formula (I), at least one of Rto Rand at least one of Rto Rare the same or different and are selected from Cl, Br, F, CN, Cto Calkyl, or Cto Ccycloalkyl, which alkyl or cycloalkyl is optionally substituted by one or more halogens, and the others of Rto Rare hydrogen, and Rto Rare the same or different and are selected from H, Cto Calkyl, Cto Ccycloalkyl, —O—Cto Calkyl, or —O—Cto Ccycloalkyl.'}3. An air-stable Ni(R)—complex according to claim 1 ,wherein Ni represents Ni(0),wherein R is the same or different and represents a trans-stilbene of the Formula (I);{'sup': 3', '8', '1', '10', '11', '12, 'sub': 1', '8', '1', '6', '1', '6', '3', '6', '3', '6, 'wherein in Formula (I), Rand Rare the same or different and are selected from Cto Calkyl which is optionally substituted by one or more halogens, and the others of Rto Rare hydrogen, and Rto Rare the same or different and are selected from H, Cto Calkyl, —O—Cto Calkyl, Cto Ccycloalkyl or —O—Cto Ccycloalkyl.'}4. An air-stable Ni(R)—complex according to claim 1 ,wherein Ni represents Ni(0),wherein R is the same or different and represents a trans-stilbene of the Formula (I);{'sup': 3', '8', '1', '10', '11', '12, 'sub': 1', '8', '1', '6', '1', '6', '3', '6', '3', '6, 'wherein in Formula (I), Rand Rare the same or different and are selected from Cto Cperfluoro alkyl and the others of Rto Rare hydrogen, and Rto Rmay be the same or different and are selected from H, Cto Calkyl, O—Cto Calkyl, Cto Ccyclolkyl or —O—Cto Ccycloalkyl.'}5. An air-stable Ni(R)—complex according to claim 1 ,wherein Ni represents Ni(0),wherein R is the ...

METHOD FOR THE SYNTHESIS OF SOLID HETEROGENEOUS CHIRAL CATALYSTS AND THEIR USE IN STEREOSELECTIVE REACTIONS

This invention describes the methodology to produce solid heterogeneous chiral organocatalysts that can be used in condensation reactions. The catalysts can be recovered in a simple manner by filtration and can also be reused. 2. The compound of formula (I) according to claim 1 , wherein n is 0 and the α-amino acid is proline.3. The compound of formula (I) according to claim 1 , wherein n is 9 and the α-amino acid is proline.4. The compound of formula (I) according to claim 2 , wherein X is 1 and Y is 3.5. The compound of formula (I) according to claim 3 , wherein X is 1 and Y is 6.6. A method for forming chiral carbon-carbon bonds comprising performing a reaction for forming carbon-carbon bonds in the presence of the compound of formula (I) according to as catalyst claim 1 , wherein the reaction for forming carbon-carbon bonds is selected from the group consisting of an aldol condensation claim 1 , a Michael addition claim 1 , a Mannich reaction claim 1 , and a Henry reaction.7. The method according to claim 6 , wherein the reaction for forming carbon-carbon bonds is performed in an aqueous reaction medium or an organic reaction medium at a temperature of −78° C. to 40° C.8. The method according to claim 6 , wherein the reaction for forming carbon-carbon bonds is performed in an aqueous reaction medium comprising a phosphate buffer having pH 7 at a temperature between 0° C. and 10° C. This application is a Divisional of co-pending U.S. patent application Ser. No. 14/085,003 filed Nov. 20, 2013, and the disclosure of which is incorporated herein by reference.This invention describes a method for the synthesis of solid heterogeneous chiral catalysts and their use in stereoselective reactions. Particularly, the invention describes a methodology for obtaining organic catalysts immobilized in a silicon oxide matrix. These catalysts are applied in some stereoselective reactions; they are easily recovered from the reaction mixture and are reused.There is a set of ...

Decarboxylative conjugate additions and applications thereof

Synthetic methods are described herein operable to efficiently produce a wide variety of molecular species through conjugate additions via decarboxylative mechanisms. For example, methods of functionalization of peptide residues are described, including selective functionalization of peptide C-terminal residues. In one aspect, a method of peptide functionalization comprises providing a reaction mixture including a Michael acceptor and a peptide and coupling the Michael acceptor with the peptide via a mechanism including decarboxylation of a peptide reside.

PRODUCTION METHOD FOR 5,5-DI-SUBSTITUTED-4,5-DIHYDROISOXAZOLE

The objective of the present invention is to provide a production method for a 4,5-dihydroisoxazole represented by formula (3), which is safe, industrially desirable, economical, and environmentally friendly. 2. The process according to claim 1 , wherein the reaction of the compound of the formula (1) with hydroxylamine is performed in the presence of water.3. The process according to claim 1 , wherein the reaction of the compound of the formula (1) with hydroxylamine is performed in the presence of 100 mol % or more of water based on 1 mol of the compound of the formula (1).4. The process according to claim 1 , wherein the reaction of the compound of the formula (1) with hydroxylamine is performed in the presence of 100 mol % to 1000 mol % of water based on 1 mol of the compound of the formula (1).5. The process according to claim 1 , wherein the catalyst is an acid catalyst.6. The process according to claim 5 , wherein the acid catalyst is one or more acids selected from the group consisting of mineral acids claim 5 , carboxylic acids claim 5 , and sulfonic acids.7. The process according to claim 5 , wherein the acid catalyst is one or more acids selected from the group consisting of nitric acid claim 5 , trifluoroacetic acid claim 5 , maleic acid claim 5 , and p-toluenesulfonic acid.8. The process according to claim 5 , wherein the acid catalyst is trifluoroacetic acid.9. The process according to claim 1 , wherein the catalyst is an acid-base catalyst.10. The process according to claim 9 , wherein the acid of the acid-base catalyst is one or more acids selected from the group consisting of mineral acids claim 9 , carboxylic acids claim 9 , and sulfonic acids.11. The process according to claim 9 , wherein the acid of the acid-base catalyst is one or more acids selected from the group consisting of nitric acid claim 9 , trifluoroacetic acid claim 9 , maleic acid claim 9 , and p-toluenesulfonic acid.12. The process according to claim 9 , wherein the acid of the acid ...

MANGANESE BASED COMPLEXES AND USES THEREOF FOR HOMOGENEOUS CATALYSIS

The present invention relates to novel manganese complexes and their use, inter alia, for homogeneous catalysis in (1) the preparation of imine by dehydrogenative coupling of an alcohol and amine; (2) C—C coupling in Michael addition reaction using nitriles as Michael donors; (3) dehydrogenative coupling of alcohols to give esters and hydrogen gas (4) hydrogenation of esters to form alcohols (including hydrogenation of cyclic esters (lactones) or cyclic di-esters (di-lactones), or polyesters); (5) hydrogenation of amides (including cyclic dipeptides, lactams, diamide, polypeptides and polyamides) to alcohols and amines (or diamine); (6) hydrogenation of organic carbonates (including polycarbonates) to alcohols or hydrogenation of carbamates (including polycarbamates) or urea derivatives to alcohols and amines; (7) dehydrogenation of secondary alcohols to ketones; (8) amidation of esters (i.e., synthesis of amides from esters and amines); (9) acylation of alcohols using esters; (10) coupling of alcohols with water and a base to form carboxylic acids; and (11) preparation of amino acids or their salts by coupling of amino alcohols with water and a hydrogenative coupling of alcohols and amines; (13) preparation of imides from diols. 2. The complex of claim 1 , wherein X′ is bromide claim 1 , Lis phosphine (PRR) or amine (NRR) claim 1 , Lis phosphine (PRR) claim 1 , Land Lare CO claim 1 , Z is zero substituents claim 1 , or any combination thereof.3. (canceled)4. (canceled)5. (canceled)6. (canceled)7. (canceled)9. (canceled)10. (canceled)12. (canceled)13. (canceled)15. (canceled)17. (canceled)18. (canceled)20. The complex of claim 19 , wherein X′ is bromide or hydride claim 19 , Lis phosphine (PRR) or amine (NRR) claim 19 , Lis phosphine (PRR) claim 19 , Land Lare CO claim 19 , Z is zero substituents claim 19 , or any combination thereof.21. (canceled)22. (canceled)23. (canceled)24. (canceled)25. (canceled)26. (canceled)28. (canceled)29. (canceled)31. (canceled)32. ( ...

CATALYSTS AND METHODS FOR ENANTIOSELECTIVE CONJUGATE ADDITIONS OF AMINES TO UNSATURATED ELECTROPHILES

Disclosed are complexes and methods of using the complexes as catalysts for addition of amines to unsaturated electrophiles, as well as novel compounds produced by the disclosed complexes and methods. The disclosed methods may utilize the disclosed complexes as catalysts for adding unprotected primary amines and secondary amines to unsaturated electrophiles in an enantioselective manner to produce novel compounds which may include amino substituted succinimide compounds. 2. The complex of claim 1 , wherein R is selected from the group consisting of naphthalene claim 1 , phenanthrene claim 1 , SiPh claim 1 , and CF.3. The complex of claim 1 , wherein R is selected from the group consisting of 1-naphthalene claim 1 , 2-naphthalene claim 1 , 1-phenanthrene claim 1 , 2-phenanthrene claim 1 , and 9-phenanthrene.4. The complex of claim 1 , wherein R is 9-phenanthrene.5. The complex of claim 1 , wherein M is an alkaline earth metal.6. The complex of claim 1 , wherein M is Ca.8. The complex of claim 7 , wherein R is selected from the group consisting of naphthalene claim 7 , phenanthrene claim 7 , SiPh claim 7 , and CF.9. The complex of claim 7 , wherein R is selected from the group consisting of 1-naphthalene claim 7 , 2-naphthalene claim 7 , 1-phenanthrene claim 7 , 2-phenanthrene claim 7 , and 9-phenanthrene.10. The complex of claim 7 , wherein R is 9-phenanthrene.11. The complex of claim 7 , wherein M is an alkaline earth metal.12. The complex of claim 7 , wherein M is Ca.13. A method for conjugating an amine to an unsaturated electrophile claim 1 , the method comprising reacting the amine and the unsaturated electrophile in the presence of the complex of as a catalyst in a reaction mixture claim 1 , the method optionally including recycling the complex for a subsequent reaction claim 1 , optionally wherein the amine is unprotected.14. A method for conjugating an amine to an unsaturated electrophile claim 7 , the method comprising reacting the amine and the unsaturated ...

Bifunctional chiral organocatalytic compound having excellent enantioselectivity, preparation method therefor, and method for producing non-natural gamma-amino acid from nitro compound by using same

The present invention relates to a bifunctional chiral organocatalytic compound having excellent enantioselectivity, a preparation method therefor, and a method for producing a non-natural gamma amino acid from a nitro compound by using the chiral organocatalytic compound. According to the present invention, the bifunctional chiral organocatalytic compound having excellent enantioselectivity can be easily synthesized, gamma-amino acids with high optical selectivity can be obtained at a high yield by an economical and convenient method using the chiral organocatalytic compound, and various (R)-configuration gamma-amino acids, which are not present in nature, can be produced with high optical purity in large quantities by using a small amount of a catalyst, and therefore, the present invention can be widely utilized in various industrial fields including the pharmaceutical industry.

METHODS USED IN MICRO-CHANNEL REACTORS WITH A TIED CATALYST AND A BOUND CATALYST OR BOUND CHIRAL TOOLS

Polymer-supported metal complex catalyst

Main-group metal based asymmetric catalysts and applications thereof

The present invention relates to a method and catalysts for the stereoselective addition of a nucleophile to a reactive π-bond of a substrate. The chiral, non-racemic catalysts of the present invention constitute the first examples of catalysts for nucleophilic additions that comprise a main-group metal and a tri- or tetra-dentate ligand.

Tethered catalyst processes in microchannel reactors and systems containing a tethered catalyst or tethered chiral auxiliary

The invention provides systems and methods for conducting reactions in which a reactant contacts a tethered catalyst and/or tethered chiral auxiliary in a microchannel and is converted to product.

塩基触媒及びカルボニル化合物誘導体の製造方法

(57)【要約】 【課題】 アルドール反応等に適用できる、高活性で目 的とする生成物を高い選択率で得ることができる効率の 良い塩基触媒を提供することを課題とする。 【解決手段】 アルカリ金属のアルコキシド、水酸化物 及び酸化物からなる群から選ばれる一種以上のアルカリ 金属化合物とアルカリ土類金属酸化物とをアルカリ金属 化合物の重量／アルカリ土類金属酸化物の重量＝０．０ ０５〜１の範囲で調製して得られる塩基触媒をアルデヒ ドの縮合反応に用いてグリコールモノエステルを製造す る。

Weakly coordinating anions containing polyfluoroalkoxide ligands

A compound comprising a polyfluorinated anion and the use thereof is provided. Specifically, the present invention provides a compound comprising an anion which comprises a polyfluorinated alkoxide coordinated to a transition metal, or a Group III, IV or V element.

微囊包封的路易斯酸

本发明提供一种微囊包封的路易斯酸，其特征在于，路易斯酸是通过配价键载在有机聚合物形成的微胶囊上，作为一种新的载在聚合物上路易斯酸，以便克服常规的载在聚合物上的催化剂的技术性限制，另外，解决了在反应体系的制备、与反应产物的分离、和具有大的工业价值的路易氏酸催化剂的回收中所伴随的问题。

Weakly coordinating anions with polyfluoroalkoxide ligands

(57)【要約】 本発明は、ポリフルオロアルコキシドを有する化合物およびその使用（特に、電池および他の電気化学デバイスにおける電解質としての使用）に関する。本発明により、ポリフッ素化アニオンを含む化合物およびその使用が提供される。特に、本発明は、遷移金属、またはＩＩＩ族元素、ＩＶ族元素またはＶ族元素に配位する、ポリフッ素化アルコキシドを含むアニオンを含む化合物を提供する。弱配位性アニオンを有する化合物は、電解質および種々の有機反応における触媒の対イオンとしての適用を含む、種々の適用において有用である。

Weakly coordinating anions containing polyfluoroalkoxide ligands

A compound comprising a polyfluorinated anion and the use thereof is provided. Specifically, the present invention provides a compound comprising an anion which comprises a polyfluorinated alkoxide coordinated to a transition metal, or a Group III, IV or V element.

Microencapsulated lewis acid

본 출원의 발명은 종래의 폴리머담지 촉매의 기술적한계를 극복하고, 더구나 공업적 유용성이 큰 루이스산 촉매에 관해서, 반응계의 조제나 반응생성물과의 분리와 그 회수에 동반하는 문제점을 더 해결하기 위해서 지금까지 알려져 있지 않은 신규한 폴리머담지 루이스산으로서 루이스산이 유기 폴리머의 마이크로 캡슐에 배위결합으로 담지되어 있는 것을 특징으로 하는 마이크로캡슐화 루이스산을 제공한다. The invention of the present application overcomes the technical limitations of the conventional polymer supported catalyst and further solves the problems associated with preparation of the reaction system, separation from the reaction product, and recovery with respect to Lewis acid catalysts having high industrial utility. Provided as a novel polymer-supported Lewis acid not known so far is a microencapsulated Lewis acid characterized in that the Lewis acid is supported by coordination bond in the microcapsule of the organic polymer.

Polymer-supported arylbis (perfluoroalkylsulfonyl) methane

Salts of heterocyclic anions and their uses as ionic conductive materials

Perfluorinated amide salts and their use as ion-conducting substances

Polymer-supported transition metal catalyst complexes and methods of use

전이 금속 복합체를 형성하도록 전이 금속 함유 화합물의 결합을 위한 여러 자리 리간드로 기능화된 중합체를 포함하는 촉매 조성물로, 상기 기능화된 중합체는 수 평균 분자량이 약 5,000 내지 30,000g/mol이고, 다분산 지수가 약 1.0 내지 2.0이다. 이 촉매는 히드로포르밀화 반응에 사용되고, 바람직하게는 이것의 액체상이 압축된 기체로 부피팽창된 것이고, 나노 여과를 사용하여 쉽게 재활용할 수 있다. A catalyst composition comprising a multidentate ligand-functionalized polymer for bonding transition metal-containing compounds to form a transition metal complex, The functionalized polymer has a number average molecular weight of about 5,000 to 30,000 g / mol and a polydispersity index of about 1.0 to 2.0. The catalyst is used in a hydroformylation reaction, preferably the liquid phase thereof is expanded to a compressed gas and can be easily recycled using nanofiltration.

Asymmetric catalysis based on chiral phospholanes and hydroxyl phospholanes

Chiral phosphine ligands derived from chiral natural products including D-mannitol and tartaric acid. The ligands contain one or more 5-membered phospholane rings with multiple chiral centers, and provide high stereoselectivity in asymmetric reactions.

High polymer-supported arylbis(perfluoroalkylsulfonyl)-methane

本发明提供一种固体酸催化剂，其可非常有效地实施采用布朗斯台德酸和路易斯酸催化剂的反应，例如使醇的苯甲酰化反应也容易实施，而且该催化剂容易回收和再利用，从毒性和环境等方面来看也是优异的催化剂。通过将通式[1](式[1]中，R 1 为取代或未取代的芳基，Rf 1 和Rf 2 相互独立地表示全氟代烷基)表示的芳基二(全氟代烷基磺酰基)甲烷，例如五氟代苯基二(全氟代烷基磺酰基)甲烷的对位承载在聚苯乙烯树脂上，得到用通式[3](式[3]中，R 1 为取代或未取代的亚芳基，Rf 1 和Rf 2 同上)表示的聚苯乙烯承载的芳基二(全氟代烷基磺酰基)甲烷。

OPTICALLY ACTIVE FLUORINATED BINAPHTHOL DERIVATIVES

Weakly coordinating anions containing polyfluoroalkoxide ligands

本发明提供了一种包括多氟代阴离子的化合物及其用途。具体地说，本发明提供了一种包括阴离子的化合物，所述阴离子包括一种与过渡金属或III，IV或V族元素配位的多氟代烷氧离子。

Microencapsulated Lewis acid

Catalysts Comprising N-Substituted Cyclic Imides and Processes for Preparing Organic Compounds with the Catalysts

본 발명의 촉매는, 하기 화학식 I로 표시되는 N-치환 환상 이미드 골격을 갖는 이미드계 화합물로 구성되어 있다. 바람직한 R은 가수분해성 보호기이다. R은, 예를 들면 카르복실산, 술폰산, 탄산, 카르밤산, 황산, 질산, 인산, 붕산 등의 산에서 OH기를 제외한 기일 수도 있다. 상기 촉매는, 상기 이미드계 화합물과 금속 화합물과의 조합으로 구성되어 있을 수도 있다. 상기 촉매의 존재하에서 (A) 라디칼을 생성할 수 있는 화합물과 (B) 라디칼 포착성 화합물을 반응시킴으로써 상기 화합물 (A)와 화합물 (B)의 부가 또는 치환 반응 생성물 또는 그들의 유도체를 생성시킬 수 있다. 이 촉매에 따르면, 온화한 조건하에서 부가 또는 치환 반응 등에 의해 유기 화합물을 높은 선택률 및 수율로 제조할 수 있다. The catalyst of the present invention is composed of an imide compound having an N-substituted cyclic imide skeleton represented by the following general formula (I). Preferred R is a hydrolyzable protecting group. R may be group which removed OH group from acids, such as carboxylic acid, a sulfonic acid, carbonate, carbamic acid, sulfuric acid, nitric acid, phosphoric acid, a boric acid, for example. The said catalyst may be comprised by the combination of the said imide type compound and a metal compound. By reacting a compound capable of generating (A) radicals with (B) a radical trapping compound in the presence of the catalyst, addition or substitution reaction products of the compound (A) with compound (B) or derivatives thereof can be produced. . According to this catalyst, organic compounds can be produced in high selectivity and yield by addition or substitution reaction or the like under mild conditions. <화학식 I> <Formula I> 식 중, R은 히드록실기의 보호기를 나타낸다. In the formula, R represents a protecting group of a hydroxyl group. N-치환 환상 이미드, 촉매, 유기 화합물 N-substituted cyclic imides, catalysts, organic compounds

Cycloaliphatic/aromatic diphosphines and use thereof in catalysis

Polymer-supported metal complex catalyst

Highly enantioselective bifunctional chiral organocatalytic compound, method for preparing the same, and method for preparing non-natural gamma-amino acid from nitrocompound using thereof

본 발명은 입체선택성이 우수한 이 작용성 유기 키랄 촉매 화합물 및 그 제조 방법과, 상기 유기 키랄 촉매 화합물을 이용한 나이트로 화합물로부터의 비천연 감마-아미노산의 제조 방법에 관한 것이다.

Solvent-free catalyst and preparation method and application thereof

本发明属于催化剂领域，涉及异斯特维醇衍生物，特别是指一种无溶剂催化剂及其制备方法和应用。所述的异斯特维醇衍生物通过在手性骨架上引入取代的方酰胺基团，实现“优势骨架合理组合”。该类衍生物通过异斯特维醇胺类衍生物和方酸二甲酯以及环己二胺衍生物经两步亲核取代反应制得，合成步骤简单，反应条件温和。本发明同时还提供了该衍生物作为有机催化剂在无溶剂条件下在合成硝基取代手性化合物中的应用。

Proton conductor in liquid form

Chiral amino acid esters compound and preparation method and purposes

本发明涉及一种手性氨基酸酯类化合物及制备方法和用途。具体地，本发明利用一价铑金属与手性双烯配体形成的配合物催化有机硼试剂对α‑氨甲基丙烯酸酯、α‑氨乙基丙烯酸酯或α‑氨丙基丙烯酸酯类底物及其衍生物进行1,4‑加成/不对称质子化反应，以水为质子源，得到相应光学活性非天然β 2 ‑氨基酸酯、γ 2 ‑氨基酸酯及δ 2 ‑氨基酸酯类化合物。本发明实现了高光学纯度非天然β 2 ‑或γ 2 ‑或δ 2 ‑氨基酸酯的催化不对称合成，方法简单、高效。

Polymer-supported transition metal catalyst complexes and methods of use

A catalyst composition comprising a polymer functionalized with a ligand for binding a transition metal containing compound to form a transition metal complex, wherein said functionalized polymer has a number average molecular weight of about 5,000 to 30,000 g/mol and a polydispersity index of about 1.0 to 2.0. The catalyst is used in a hydroformylation reaction, preferably one in which the liquid phase has been volumetrically expanded with a compressed gas, is readily recyclable using nanofiltration.

Surface modified carbonaceous materials

Grafting a polymer at the surface of a carbonated material containing carboxyl amine and/or hydroxyl functions at its surface. This material is suspended in a solution comprising the polymer to be grafted, which includes a carboxyl amine and/or hydroxyl function, the solution also comprising a solvent of the polymer. This is followed by a treatment causing dehydration into a carboxyl function, an amide and/or hydroxyl function and the polymer is thus grafted on the carbonated material by means of ester or amide bonds. Utilization in the cathode or anode of an electrochemical generator, in a polymer material with low polarity, in an ink, and as a conductive deposit on flexible plastic used as electrical contact, electromagnetic protection and antistatic protection.

Optically active fluorinated binaphthol derivative

A novel optically active binaphthol derivative with which a higher reaction yield and a higher optical yield (selectivity) can be attained in asymmetric synthesis and which is useful as an asymmetric catalyst, etc.; an asymmetric catalyst comprising the derivative; and a method of asymmetric synthesis. The optically active fluorinated binaphthol derivative is represented by formula (I) wherein R1 and R2 each represents a fluorohydrocarbon group.

Polymer-supported metal complex catalyst

【課題】 高分子担持ロジウム(II)触媒、この触媒を用いたα-ジアゾカルボニル化合物の炭素-炭素多重結合への付加、C-H及びX-H (X = N, O, S, Se, Siなど)結合への挿入あるいはイリド形成を引き金とする転位・付加環化反応に関する。【解決手段】 カルボン酸が置換したスチレン誘導体、スチレン及び両末端にビニルベンジルオキシ基を置換した直鎖アルカンの共重合により調製した不溶性高分子とロジウム(II)カルボキシラート錯体の配位子交換反応により新規不溶性高分子担持ロジウム(II)錯体の調製した。即ち、金属を架橋高分子に担持させてなる下式（化１）【化１】（式中、Ｍ１とＭ２はロジウム等、Ｘは酸素原子等、Ｒ４はアルキル基等を表し、ｋ＋ｌ＋ｍに対してｋは１〜１５％、ｍは１〜５％、ｌは残部などを表し、ｎは４などを表し、Ｒ１はアルキル-２-（４’-アルキルオキシフタルイミドメチル基）等、Ｒ２はフェニル基等、Ｒ３は4,4'-(1,3-プロピレン-1,3-ジオキシメチル)フェニル基等を表す。）で表される高分子担持金属錯体触媒である。【選択図】 なし PROBLEM TO BE SOLVED: To add a polymer-supported rhodium (II) catalyst, α-diazocarbonyl compound to carbon-carbon multiple bond, CH and XH (X = N, O, S, Se, Si, etc.) bond using this catalyst The present invention relates to rearrangement and cycloaddition reactions triggered by insertion into or ylide formation. SOLUTION: Ligand exchange reaction of rhodium (II) carboxylate complex with insoluble polymer prepared by copolymerization of styrene derivative substituted with carboxylic acid, styrene and linear alkane substituted with vinylbenzyloxy group at both ends. A novel insoluble polymer-supported rhodium (II) complex was prepared by That is, the following formula (Chemical Formula 1) in which a metal is supported on a crosslinked polymer (wherein M1 and M2 are rhodium, X is an oxygen atom, R4 is an alkyl group, etc., and k + 1 + m) K represents 1 to 15%, m represents 1 to 5%, l represents the remainder, n represents 4 and the like, R1 represents alkyl-2- (4'-alkyloxyphthalimidomethyl group) and the like, and R2 represents phenyl R3 is a polymer-supported metal complex catalyst represented by 4,4 ′-(1,3-propylene-1,3-dioxymethyl) phenyl group, etc.). [Selection figure] None

Phosphine ligands compound and its intermediate and preparation method based on tetramethyl spiro indan skeleton and purposes

本发明公开了一种基于四甲基螺二氢茚骨架的膦配体化合物及其中间体和制备方法与用途。所述的膦配体化合物是具有通式I或通式II所示结构的化合物或所述化合物的对映体、消旋体或非对映异构体。该膦配体以廉价易得的四甲基螺二氢茚二酚为原料，经由通式III作为关键中间体的制备路线获得。本发明开发了一类新型的膦配体，可用于催化有机反应，特别是可作为手性的膦配体广泛用于包括不对称氢化和不对称烯丙基烷基化等许多不对称催化反应中，具有经济实用性和工业应用前景。

Lewis-acid metal catalyst enclosed in polymer

To enclose a Lewis-acid metal in a polymer and enable the resultant Lewis-acid metal catalyst to be recovered while maintaining the function of the catalyst. The polymer-enclosed Lewis-acid metal catalyst comprises a crosslinked polymer and a Lewis-acid metal enclosed therein, and the crosslinked polymer is one obtained from a crosslinkable polymer by crosslinking crosslinking groups contained in the polymer. The catalyst is characterized in that the crosslinkable polymer has at least one kind of monomer units having a hydrophobic substituent and a hydrophilic substituent having a crosslinking group and that the hydrophobic substituent comprises an aromatic substituent. This catalyst can be obtained by mixing an organic solution containing the crosslinkable polymer and a Lewis-acid metal with a poor solvent and subjecting the resultant polymer micells containing the Lewis-acid metal enclosed therein to a crosslinking reaction. This catalyst is useful as a catalyst for aldol reaction, cyanation reaction, allylation reaction, Michael reaction, Mannich reaction, Diels-Alder reaction, or Friedel-Crafts reaction.

Catalyst comprising N-substituted cyclic imide compound and process for producing organic compound using the catalyst

A catalyst of the invention includes an imide compound having a N-substituted cyclic imide skeleton represented by following Formula (I): wherein R is a hydroxyl-protecting group. Preferred R is a hydrolyzable protecting group. R may be a group obtained from an acid by eliminating an OH group therefrom. Such acids include, for example, carboxylic acids, sulfonic acids, carbonic acid, carbamic acid, sulfuric acid, nitric acid, phosphoric acids and boric acids. The catalyst may include the imide compound and a metallic compound in combination. In the presence of the catalyst, (A) a compound capable of forming a radical is allowed to react with (B) a radical scavenging compound and thereby yields an addition or substitution reaction product of the compound (A) and the compound (B) or a derivative thereof. This catalyst can produce an organic compound with a high selectivity in a high yield as a result of, for example, an addition or substitution reaction under mild conditions.

Mixtures of chiral monophosphorus compounds used as ligand systems for asymmetric transition metal catalysis

Perfluorinated amide salts and their uses as ionic conducting materials

The invention concerns ionic compounds in which the anionic load has been delocalized. A compound disclosed by the invention is comprised of an amide or one of its salts, including an anionic portion combined with at least one cationic portion M +m in sufficient numbers to ensure overall electronic neutrality; the compound is further comprised of M as a hydroxonium, a nitrosonium NO + , an ammonium —NH 4 +, a metallic cation with the valence m, an organic cation with the valence m, or an organometallic cation with the valence m. The anionic portion matches the formula R F —SO x —N − Z, wherein R F is a perfluorinated group, x is 1 or 2, and Z is an electroattractive substituent. The compounds can be used notably for ionic conducting materials, electronic conducting materials, colorants, and the catalysis of various chemical reactions.

Transition metal-catalyzed reaction, chiral ligands for these catalyzes and their preparation

Pentacyclic anion salts or tetrazapentalene derivatives and their uses as ionic conducting materials

The invention relates to ionic compounds in which the anionic load has been delocalized. A compound disclosed by the invention includes an anionic portion combined with at least one cationic portion M m+ in sufficient numbers to ensure overall electronic neutrality; the compound is further comprised of M as a hydroxonium, a nitrosonium NO + , an ammonium —NH 4 + , a metallic cation with the valence m, an organic cation with the valence m, or an organometallic cation with the valence m. The anionic load is carried by a pentacyclical nucleus of tetrazapentalene derivative bearing electroattractive substituents. The compounds can be used notably for ionic conducting materials, electronic conducting materials, colorant, and the catalysis of various chemical reactions.

Chiral diazaphospholidine ligands

The application relates to diazaphospholidine compounds of Formula 1 and Formula 2: where: A and B are independently selected from C(R 22 R 23 ) and C(R 22 R 23 )C(R 24 R 25 ); R 1 , R 2 , R 3 , R 4 , R 18 , R 19 , R 20 , R 21 , R 22 , R 23 , R 24 and R 25 each may not be present and each may be independently selected from H, halide —OH, —SO 2 R 26 (where R 26 is selected from a group as defined for R 22 , R 23 , R 24 and R 25 ), —SH, —NO 2 , —NH 2 , ═O, ═S, straight chain, branched chain, cyclic, saturated, non-saturated, substituted or non-substituted alkyl, hydroalkyl, carboalkyl, alkoxy, amino, alkenyl, aryl and —CH 2 Ar (where Ar is aryl or substituted aryl), preferably containing 1 to 6 carbons, or a silane containing 1 to 6 silicon atoms, wherein, where an R 1 , R 2 , R 3 , R 4 , R 18 , R 19 , R 20 , R 21 , R 22 , R 23 , R 24 and/or R 25 group is not present an unsaturated bond is formed; R 5 and R 17 are selected from H, —NH 2 , —OH, halide or a substituted or non-substituted straight or branched chain alkyl or aryl; R 6 , R 7 , R 15 and R 16 are each independently selected from halide —OH, —SO 2 , —SH, —NO 2 , —NH 2 , straight chain, branched chain, cyclic, saturated, non-saturated, substituted or non-substituted alkyl, carboalkyl, alkoxy, alkenyl, aryl and —CH 2 Ar (where Ar is aryl or substituted aryl), or a silane containing 1 to 6 silicon atoms; R 8 and R 14 are selected from H, straight, branched, cyclic, saturated, non-saturated, substituted or non-substituted alkyl, carboalkyl, alkoxy, alkenyl, aryl and —CH 2 Ar (where Ar is aryl or substituted aryl); R 9 , R 10 , R 11 , R 12 , R 13 are independently selected from halide —OH, —SO 2 , —SH, —NO 2 , —NH 2 , straight chain, branched chain, cyclic, saturated, non-saturated, substituted or non-substituted alkyl, carboalkyl, alkoxy, amino, alkenyl, aryl and —CH 2 Ar (where Ar is aryl or substituted aryl), or a silane containing 1 to 6 silicon atoms; and X is a linking group containing 1 to 12 atoms; or a ...

Ionically conductive materials containing a malononitrile-derived ionic compound and their uses

Phase selective polymer supports for catalysis

Phase-selective soluble polymer supports for catalysts are described. The catalysts utilize polystyrene copolymers having enhanced solubility in nonpolar solvents. Other catalysts of the invention utilize polyisobutylene supports. Methods of catalyzing chemical reactions using latent biphasic solvents are also disclosed.

Microencapsulated lewis acid

The invention provides a microencapsulated Lewis acid characterized in that a Lewis acid is supported through coordinate bonds on microcapsules formed of an organic polymer as a novel Lewis acid supported on a polymer in order to overcome the technical limit of conventional catalysts supported on polymers and in addition, to solve problems attendant upon the preparation of a reaction system and separation and recovery from reaction products about Lewis acid catalysts having great industrial usefulness.

Polymer-supported transition metal catalyst complexes and methods of use

一种手性樟脑磺酰肼双功能催化剂及其制备方法与应用

本发明涉及一种手性樟脑磺酰肼双功能催化剂及其制备方法和应用，该催化剂的制备方法为：手性樟脑磺酰氯、水合肼在有机酸作用下，进行氨解反应、环化反应，得到化合物2；化合物2在碱、相转移催化剂和二卤代烷作用下发生取代反应，得到化合物3；化合物3、无机碱、R 2 NHR 1 和碘化钠在有机溶剂中回流、取代反应，得到催化剂前体4；配制催化剂前体4的甲醇溶液，加入有机酸，在分批加入还原剂，得到所述手性樟脑磺酰肼双功能催化剂；本发明的催化剂可以用来催化不对称Micheal加成反应。与现有技术相比，本发明拓展了一系列的手性樟脑磺酰肼双功能催化剂，设计合成路线开发新的环境友好的有机手性催化剂，有利于保护环境、节约资源。

１−置換２−メチル−テトラヒドロピリミジンの製造法

一种手性三氮唑-噁唑啉化合物及其制备方法与应用

本发明的一种手性三氮唑‑噁唑啉化合物及其制备方法与应用属于有机合成技术领域。所述手性三氮唑‑噁唑啉化合物，结构式为： 制备方法包括点击反应、三氮唑N2取代反应、Suzuki偶联、三氮唑酯水解、与手性胺基醇酰胺化后脱水缩合等步骤。通过加入所述手性三氮唑‑噁唑啉化合物和钯盐化合物原位络合生成催化剂后在前手性有机化合物的碳碳双键上进行芳基硼酸的不对称加成制备手性有机化合物。本发明制备新型三氮唑‑噁唑啉化合物具有原料成本低、合成步骤少、实验场地要求低、反应条件相对温和、操作简单等优点。

Process of making derivatives of substituted morpholines

Provided here are methods of making derivatives and prodrugs of substituted morpholines or pharmaceutically acceptable salts thereof. Further provided are methods of making derivatives and prodrugs of substituted morpholines having the following chemical structure: (IIf)

Base catalyst and method for producing derivative of carbonyl compound

Verfahren in mikrokanalreaktoren mit gebundenem katalysator und einen gebundenen katalysator oder gebundene chirale hilfsmittel enthaltende systeme

Manganese based complexes and uses thereof for homogeneous catalysis

Process of making derivatives of substituted morpholines

Provided here are methods of making derivatives and prodrugs of substituted morpholines or pharmaceutically acceptable salts thereof. Further provided are methods of making derivatives and prodrugs of substituted morpholines having the following chemical structure:

Catalysts and methods for enantioselective conjugate addition of amines to unsaturated electrophiles

Disclosed are complexes and methods of using the complexes as catalysts for addition of amines to unsaturated electrophiles, as well as novel compounds produced by the disclosed complexes and methods. The disclosed methods may utilize the disclosed complexes as catalysts for adding unprotected primary amines and secondary amines to unsaturated electrophiles in an enantioselective manner to produce novel compounds which may include amino substituted succinimide compounds.

Decarboxylative conjugate additions and applications thereof

Synthetic methods are described herein operable to efficiently produce a wide variety of molecular species through conjugate additions via decarboxylative mechanisms. For example, methods of functionalization of peptide residues are described, including selective functionalization of peptide C-terminal residues. In one aspect, a method of peptide functionalization comprises providing a reaction mixture including a Michael acceptor and a peptide and coupling the Michael acceptor with the peptide via a mechanism including decarboxylation of a peptide reside.

Enantioselective phosphoramidite compounds and catalysts

This invention relates to phosphoramidite compounds and catalyst complexes which can be used to provide enantioselective reactions including hydroamination reactions, etherification reactions and conjugate addition reactions and allylic substitution reactions, among others. In a first aspect, the present invention is directed to phosphoramidite and related compounds according to general structure (I), where Z is absent or is a group containing O, N or S, preferably O; R1 and R2 are independently an optionally substituted C1-12 alkyl group, an optionally substituted (CH2)n-aromatic group or (CH2)n-heteroaromatic group, or are linked together to form an optionally substituted aliphatic or (CH2)n-aromatic dianion of a diol, diamine, dithiol, aminoalcohol, aminohiolate or a alcoholthiol group; R3’ and R3 are each independently H, an optionally substituted C1-C12 alkyl group or an optionally substituted (CH2)n-aromatic group with the proviso that R3’ and R3 are not both H, or together R3’ and R3 form an optionally substituted C5-C15 saturated or unsaturated carbocyclic ring; R4 is H, an optionally substituted C1-C12 alkyl group or an optionally substituted (CH2)n-aromatic group; R5 is absent, H, an optionally substituted C1-C12 alkyl group or an optionally substituted (CH2)n-aromatic or (CH2)n-heteroaromatic group; Ra and Ra’ are each independently H or a C1-C3 alkyl group, or Ra and Ra’ together with the carbon to which they are attached form a optionally substituted C5-C15 saturated or unsaturated carbocyclic or heterocyclic ring, or an aromatic or heteroaromatic ring; R6 and R7 are each independently H, an optionally substituted C1-C12 alkyl group or an optionally substituted (CH2)n-aromatic group, with the proviso that R5, R6 and R7 cannot simultaneously be H, and when Ra and Ra’, together with the carbon to which they are attached, form a carbocyclic ring, heterocyclic ring or an aromatic or heteroaromatic ring, R5 is absent or is preferably H; R6 and R7 are ...

Nitrogen heterocyclic carbene catalyst and preparation method therefor

A nitrogen heterocyclic carbene catalyst, having a structural formula represented by formula I:Ar1 and Ar2 in the formula I represent any one independently selected from the group consisting of an aryl, a substituted aryl, a heteroaryl, and a substituted heteroaryl, respectively; and X represents an oxygen atom or a sulfur atom. Thiourea (urea) is introduced to the nitrogen heterocyclic carbene skeleton as another active site, which can form various bifunctional nitrogen heterocyclic carbene catalysts.

Manganese based complexes and uses thereof for homogeneous catalysis

The present invention relates to novel manganese complexes and their use, inter alia, for homogeneous catalysis in (1) the preparation of imine by dehydrogenative coupling of an alcohol and amine; (2)C—C coupling in Michael addition reaction using nitriles as Michael donors; (3) dehydrogenative coupling of alcohols to give esters and hydrogen gas (4) hydrogenation of esters to form alcohols (including hydrogenation of cyclic esters (lactones) or cyclic di-esters (di-lactones), or polyesters); (5) hydrogenation of amides (including cyclic dipeptides, lactams, diamide, polypeptides and polyamides) to alcohols and amines (or diamine); (6) hydrogenation of organic carbonates (including polycarbonates) to alcohols or hydrogenation of carbamates (including polycarbamates) or urea derivatives to alcohols and amines; (7) dehydrogenation of secondary alcohols to ketones; (8) amidation of esters (i.e., synthesis of amides from esters and amines); (9) acylation of alcohols using esters; (10) coupling of alcohols with water and a base to form carboxylic acids; and (11) preparation of amino acids or their salts by coupling of amino alcohols with water and a base. (12) preparation of amides (including formamides, cyclic dipeptides, diamide, lactams, polypeptides and polyamides) by dehydrogenative coupling of alcohols and amines; (13) preparation of imides from diols.

Air-stable Ni(0)-olefin complexes and their use as catalysts or precatalysts

The present invention relates to air stable, binary Ni(0)-olefin complexes and their use in organic synthesis.

Cycloaliphatisch-aromatische diphosphine und ihre verwendung in der katalyse

Neue diphosphine, deren komplexe mit übergangsmetallen und deren verwendung in der asymmetrischen synthese

Process for producing optically active compound

A highly efficient process is provided for producing an optically active compound having high optical purity by an asymmetric reaction using as a catalyst a transition metal complex having an optically active nitrogen-containing compound as an asymmetric ligand.

基於錳的配合物及其在均相催化中的用途

Method of selective paradichlorobenzene preparation with improved catalytic system recovery

Benzene and/or monochlorobenzene were chlorinated with molecular chlorine to obtain paradichlorobenzene with high selectivity. A batch reactor was used for this purpose, with a highly selective catalytic system consisting of SbCl 3 and a phenothiazine derivative. The entire process was improved with the introduction of a new catalytic system recovery method, which was based on returning the mother liquid containing the catalytic system to the process after prior separation from the fresh post-reaction mixture by distillation of unreacted raw materials under reduced pressure and recycling them, as well as crystallization of paradichlorobenzene from the depleted liquid after vacuum distillation. The invention has a significant effect on improving the economics of the entire process.

Air-stable ni(0)-olefin complexes and their use as catalysts or precatalysts

The present invention relates to air stable, binary Ni(0)-olefin complexes and their use in organic synthesis.

光学活性ニトロ化合物およびシアノ化合物の製造方法

【課題】本発明の課題は、簡便で実用的なマイケル反応により、高効率的かつ高立体選択的にニトロ化合物およびシアノ化合物を製造する。 【解決手段】光学活性含窒素化合物および周期表第VIII族金属錯体を作用させることにより得られる金属錯体を、請求項１に記載の化学式（Ａ）で表される化合物と、化学式（Ｂ）で表される化合物の不斉マイケル反応に用いて、化学式（Ｃ）で表される光学活性ニトロ化合物およびシアノ化合物を製造する方法。

Process for preparing optically active nitro compounds and cyano compounds

A process for preparing optically active nitro compounds and cyano compounds using a metal complex, which is obtained by reaction of an optically active nitrogen-containing compound and a periodic table group VIII metal complex, in the asymmetric Michael reaction.

３－（３－オキソ－２－ペンチル）シクロペンチルマロン酸ジメチルの合成方法及び触媒

【課題】本発明は、３－（３－オキソ－２－ペンチル）シクロペンチルマロン酸ジメチルの合成方法及び触媒を開示する。【解決手段】前記合成方法では、２－ペンチル－２－シクロペンテノン、マロン酸ジメチルを原料とし、触媒の存在で反応し、前記３－（３－オキソ－２－ペンチル）シクロペンチルマロン酸ジメチルを調製し取得し、前記触媒がアルカリイオン液体であり、前記アルカリイオン液体のカチオン部が含窒素複素環式化合物から形成され、前記アルカリイオン液体のｐＨが１０以上である。この合成方法は、環境に優しく、反応が安定し、製造コストが低く、且つ上記アルカリイオン液体を触媒として採用するため、２－ペンチル－２－シクロペンテノンの転化率が明らかに向上する。