05-12-2013 дата публикации
Номер: US20130324571A1
Принадлежит:
The present invention relates to novel N-(imidazolidin-2-ylidene)-heterocyclo penta[b]pyridine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals. 2. The method according to claim 1 , wherein the disorder is a retinal disease selected from: age related macular degeneration claim 1 , wet macular degeneration claim 1 , dry macular degeneration claim 1 , geographic atrophy claim 1 , diabetic retinopathy claim 1 , diabetic macular edema claim 1 , tumors claim 1 , retinal vein occlusion claim 1 , ocular hypertension claim 1 , glaucoma claim 1 , retinitis pigmentosa and neuritis secondary to multiple sclerosis.3. The method according to claim 1 , wherein the disorder is a skin condition selected from: rosacea claim 1 , sunburn claim 1 , psoriasis claim 1 , acne rosacea claim 1 , menopause-associated hot flashes claim 1 , hot flashes resulting from orchiectomyatopic dermatitis claim 1 , photoaging claim 1 , seborrheic dermatitis claim 1 , acne claim 1 , allergic dermatitis claim 1 , redness of the skin claim 1 , telangiectasia of the face claim 1 , rhinophymia claim 1 , red bulbous nose claim 1 , acne-like skin eruptions claim 1 , burning or stinging sensation of the face claim 1 , irritated and bloodshot and watery eyes claim 1 , erythema of the skin claim 1 , cutenous hyperactivity with dilation of blood vessels of the skin claim 1 , Lyell's syndrome claim 1 , Stevens-Johnson syndrome claim 1 , erythema multiforme minor and erythema multiforme major.4. The method according to claim 1 , wherein the disorder is glaucoma claim 1 , elevated intraocular pressure claim 1 , ischemic neuropathies claim 1 , optic neuropathy claim 1 , pain claim 1 , visceral pain claim 1 , corneal pain claim 1 , headache pain claim 1 , migraine claim 1 , cancer pain claim 1 , back pain claim 1 , irritable bowel syndrome pain claim 1 , muscle pain and pain associated with diabetic neuropathy claim 1 , diabetic retinopathy claim 1 ...
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