16-05-2013 дата публикации
Номер: US20130123105A1
Автор:
EVANS Richard Roger,
Grossmann Klaus,
Hutzler Johannes,
Kraus Helmut,
Kreuz Klaus,
Major Julia,
Michrowska-Pianowska Anna Aleksandra,
Moberg William Karl,
NEWTON Trevor William,
PARRA RAPADO Liliana,
QU Tao,
Reingruber Ruediger,
SEITZ Thomas,
SIMON Anja,
Song Dschun,
Stelzer Frank,
Van Der Kloet Andree,
WITSCHEL Matthias
The invention relates to isoxazolo[5,4-b]pyridine compounds of formula I, 116-. (canceled)18. The method as claimed in claim 17 , wherein in formula I{'sup': '1', 'sub': 1', '6', '1', '6, 'Ris hydrogen, halogen, C-C-alkyl, or C-C-haloalkyl.'}19. The method as claimed in claim 17 , wherein in formula I{'sup': '2', 'sub': 1', '6', '1', '6', '1', '6', '3', '6', '3', '6', '2', '6', '2', '6, 'Ris hydrogen, C-C-alkyl, C-C-haloalkyl, C-C-hydroxyalkyl, C-C-cycloalkyl, C-C-halocycloalkyl, C-C-alkenyl, or C-C-alkynyl.'}20. The method as claimed in claim 17 , wherein in formula I{'sup': '1', 'Ris hydrogen;'}{'sup': '2', 'sub': 1', '6', '1', '6', '1', '6', '3', '6', '3', '6', '2', '6', '2', '6, 'Ris hydrogen, C-C-alkyl, C-C-haloalkyl, C-C-hydroxyalkyl, C-C-cycloalkyl, C-C-halocycloalkyl, C-C-alkenyl, or C-C-alkynyl;'}{'sup': 3', '3, 'sub': 1', '6', '1', '6', '3', '6', '1', '6', '3', '6', '1', '6', '3', '6', '3', '6', '1', '4', '3', '6', '1', '6', '1', '6', '1', '4', '1', '4', '1', '4', '1', '4', '3', '6', '2', '6', '2', '6', '1', '4', '1', '4', '1', '4', '1', '4', '1', '4', '1', '4', '1', '4, 'Ris C-C-alkyl, C-C-haloalkyl, C-C-cycloalkyl-C-C-alkyl, C-C-halocycloalkyl-C-C-alkyl, C-C-cycloalkyl, C-C-halocycloalkyl, C-C-alkyl-C-C-cycloalkyl, C-C-alkoxy, C-C-haloalkoxy, or phenyl; wherein the phenyl moieties of Rcan be unsubstituted or substituted with one or more radicals selected from the group consisting of halogen, hydroxy, nitro, cyano, C-C-alkyl, C-C-haloalkyl, C-C-alkoxy-C-C-alkyl, C-C-cycloalkyl, C-C-alkenyl, C-C-alkynyl, C-C-alkoxy, C-C-haloalkoxy, C-C-alkoxycarbonyl, C-C-alkylsulfinyl, C-C-alkylsulfonyl, amino, C-C-alkylamino, N,N-di-(C-C)-alkylamino, heterocyclyl, or phenyl;'}{'sup': 4', '5, 'X is ORor SR.'}21. The method as claimed in claim 17 , wherein in formula I{'sup': '4', 'X is OR;'}{'sup': '4', 'sub': 1', '6', '1', '6', '1', '6', '1', '6', '1', '6', '1', '6', '1', '6', '2', '6', '2', '6', '2', '6, 'Ris hydrogen, C-C-alkyl, C-C-haloalkyl, C-C-cyanoalkyl, C-C- ...
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