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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 1907. Отображено 100.
18-04-2013 дата публикации

POLYMERS FOR DELIVERING MOLECULES OF INTEREST

Номер: US20130096177A1
Автор: Creusat Gaelle, Frisch Benoit, Thomann Jean-Sébastien, Zuber Guy
Принадлежит:

The present invention relates to a new class of cationic polymers that self-assemble with a pH-sensitive dissolution switch, and their uses to deliver molecules of interest to a cell. The present invention also relates to compositions comprising said cationic polymers non-covalently associated with a molecule of interest, in particular with a siRNA. 134-. (canceled)36. The polyethylenimine of claim 35 , wherein the polyethylenimine is branched.37. The polyethylenimine of claim 35 , wherein the polyethylenimine has a molecular weight of at least 400 Da or between 500 Da to 200 claim 35 ,000 Da.38. The polyethylenimine of claim 35 , wherein the amine functions are modified or substituted by a radical X at a ratio of p from 0.1 to 0.9 claim 35 , or a ratio of p from 0.15 to 0.5 claim 35 , or a ratio of p from 0.2 to 0.4 claim 35 , or a ratio of p of about 0.30.39. The polyethylenimine of claim 35 , wherein R is independently selected from the group consisting of H claim 35 , OH claim 35 , OCH claim 35 , and NH.40. The polyethylenimine of claim 35 , wherein r is 0 or 1.42. The polyethylenimine of claim 41 , wherein Z is S.46. The polyethylenimine of claim 35 , wherein at least 3 or 4 of the 5 R are H and the other R is selected from the group consisting of H claim 35 , OH claim 35 , NH claim 35 , and OCH.47. The polyethylenimine of claim 44 , wherein at least 3 or 4 of the 5 R are H and the other R is selected from the group consisting of H claim 44 , OH claim 44 , NH claim 44 , and OCH.48. The polyethylenimine of claim 45 , wherein at least 3 or 4 of the 5 R are H and the other R is selected from the group consisting of H claim 45 , OH claim 45 , NH claim 45 , and OCH.50. The polyethylenimine of claim 49 , wherein Z is O.52. The polyethylenimine of claim 51 , wherein Z is S and r is O.54. The polyethylenimine of claim 53 , wherein Z is O.56. A composition comprising a polyethylenimine according to and a molecule of interest non-covalently associated with the ...

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Номер записи: 1
16-05-2013 дата публикации

High Capacity Oxoanion Chelating Media From Hyperbranched Macromolecules

Номер: US20130118986A1
Автор: Diallo Mamadou S., Mishra Himanshu, Yu Changjun
Принадлежит:

A resin is provided for selectively binding to certain anions in aqueous solution. The beads are prepared by cross-linking macromolecules such as hyperbranched PEI, and functionalizing with groups containing vicinal diol moieties. 1. An oxoanion-selective microparticle comprising a hyperbranched macromolecular structure (A) comprising a plurality of branches , a plurality of terminal functional groups , and a plurality of cross-linking moieties within the same molecular structure;wherein each of said plurality of branches comprises an N-substituted or N,N-substituted n-aminoalkyl moiety (B) comprising one or two substituent moieties; (a) another of said plurality of branches;', '(b) one of the plurality of terminal functional groups; or', '(c) one of the cross-linking moieties attached at a first cross-linking end, wherein the cross-linking moiety further comprises a second cross-linking end, by which the moiety is also one of said substituent moieties of one of said plurality of branches at a different location within the hyperbranched macromolecular structure A;, 'wherein each of said substituent moieties comprises one of the followingwherein A has a molecular weight of at least 1500 grams per mole;wherein A comprises essentially no primary amine moieties; andwherein each of the plurality of terminal functional groups comprises a vicinal diol moiety.2. The microparticle of claim 1 , wherein the cross-linking moieties consist of a carbon backbone of at least three carbon atoms claim 1 , each carbon atom optionally substituted with one or more functional groups.3. The microparticle of claim 2 , wherein the cross-linking moieties are selected from the group consisting of —CH—CHOH—CH— and —CH—CH—CH—4. The microparticle of claim 1 , wherein the terminal functional groups are 2 claim 1 ,3-dihydroxypropyl.5. The microparticle of claim 1 , wherein the terminal functional groups are (2R claim 1 ,3S claim 1 ,4R claim 1 ,5R)-2 claim 1 ,3 claim 1 ,4 claim 1 ,5 claim 1 ,6- ...

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Номер записи: 2
16-05-2013 дата публикации

POLYAMINE AND METHOD FOR PRODUCING THEREOF

Номер: US20130123542A1
Автор: Kitayama Hiroyuki, Monguchi Yasunari, Sajiki Hironao
Принадлежит: Rhodia Operations

A method for producing a polyamine is described that provides excellent safety, a lot of flexibility regarding a variety of its productions, and that can produce a polyamine of high-molecular weight easily and inexpensively. 1. A polyamine comprising a combination of units of formula (1) or (2):{'br': None, 'sub': 2', 'm', '2', 'n, '—(NH—(CH)—NH—(CH))—\u2003\u2003(1)'} {'br': None, '—(NH—Y—NH—Z)—\u2003\u2003(2)'}, '(in the formula (1), independently in every unit, “m” indicates an integral number of 0 or more and “n” indicates an integral number of 3 or more.)'}(in the formula (2), independently in every unit, “Y” and “Z” are the same as or different from each other, and they indicate substituted or unsubstituted groups comprising unsaturated aliphatic, cyclic aliphatic or aromatic hydrocarbon radicals that can include hetero atoms.)2. The polyamine according to claim 1 , wherein the m and/or n of the formula (1) are the same as each other among the combined units.3. The polyamine as defined by claim 1 , wherein the Y and/or Z of the formula (2) are the same as each other among combined units.4. The polyamine as defined by claim 1 , wherein the polyamine comprises a polymer with a molecular weight of 1 claim 1 ,000 or more as it is measured by a mass spectrum.5. A polyamine obtained by a reductive polycondensation polymerization of diamine and dinitrile claim 1 , the diamine is at least one member selected from the group consisting of a substituted diamine claim 1 , an unsubstituted diamine claim 1 , an aliphatic diamine claim 1 , an aromatic diamine and an aliphatic-aromatic combined diamine.6. The polyamine according to claim 5 , whereinthe aliphatic diamine is at least one member selected from the group consisting of ethylenediamine, 1,2-propylenediamine, 1,3-propylenediamine, 1,2-butylenediamine, 1,3-butylenediamine, 1,4-butylenediamine, 2,3-butylenediamine, 1,2-cyclohexanediamine, 1,3-cyclohexanediamine, 1,4-cyclohexanediamine, hydrazine, pentamethylenediamine, ...

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Номер записи: 3
23-05-2013 дата публикации

METAL SCAVENGING POLYMERS AND USES THEREOF

Номер: US20130131253A1
Автор: Mlambo Darlington, Stiles Rebecca L., Su Winston, Zinn Paul J.
Принадлежит:

A polymer, a composition, and uses for either are disclosed. The polymer is derived from at least two monomers: acrylic-x and an alkylamine, and has attached to the polymer backbone a functional group capable of scavenging at least one metal. The polymer has a polymer backbone with a fluorescing quantity of conjugated double bonds, thereby providing a method for controlling metal scavenging via fluorescence. These polymers have many uses in various media, including wastewater systems. 2. The method of claim 1 , wherein the functional group comprises at least one sulfide compound.3. The method of claim 1 , wherein the functional group is a dithiocarbamate salt group and wherein the polymer is between 5 to 100 percent functionalized with the dithiocarbamate salt group based upon the total possible functionalization of the polymer backbone.4. The method of claim 1 , wherein the at least one metal is selected from the group consisting of: copper claim 1 , nickel claim 1 , zinc claim 1 , lead claim 1 , mercury claim 1 , cadmium claim 1 , silver claim 1 , iron claim 1 , manganese claim 1 , palladium claim 1 , platinum claim 1 , strontium claim 1 , selenium claim 1 , arsenic claim 1 , cobalt claim 1 , gold claim 1 , and any combination thereof5. The method of claim 1 , further comprising a second treating of the process stream with a complexing amount of a water soluble ethylene dichloride ammonia polymer having a molecular weight of from 500 to 100 claim 1 ,000 Daltons and functionalized from 5 to 50% with dithiocarbamate salt groups.6. The method of claim 1 , further comprising: applying an oxidizing agent to a heat generating system flue gas; optionally wherein the oxidizing agent oxidizes a target species at a temperature of at least 500° C.; optionally wherein the target species is elemental mercury or derivatives thereof; and optionally wherein the oxidizing agent is at least one of the following: a thermolabile molecular halogen claim 1 , calcium bromide claim 1 , ...

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Номер записи: 4
01-08-2013 дата публикации

METHOD AND MATERIALS FOR SEPARATING NUCLEIC ACID MATERIALS

Номер: US20130193364A1
Автор: Wu Betty
Принадлежит:

Nucleic acid material can be effectively separated from a fluid under mild conditions by the use of a positively charged polymer which binds the nucleic acid material. Disclosed is a novel positively charged polymer which may be employed in the separation process. This polymer comprises an acidified polyamine, such as polyethyleneimine which has been reacted with a nonacidified polyethyleneimine in a coupling reaction. The acidified polyethyleneimine may be a coarboxylated and/or sulfonated polyethyleneimine. 1. A method for preparing a partially positively charged polyethyleneimine polymer , said method comprising the steps of:providing a first volume of a polyethyleneimine polymer;reacting said first volume of polyethyleneimine polymer with an acidifying agent so as to produce an acidified polyethyleneimine;providing a second volume of a polyethyleneimine polymer; andreacting said second volume of polyethyleneimine with said acidified polyethyleneimine so as to couple at least some of said carboxylated polyethyleneimine to said polyethyleneimine of said second volume.2. The method of claim 1 , wherein said acidifying agent is a carboxylating agent or a sulfonating agent.3. The method of claim 1 , wherein said acidifying agent is sodium chloroacetate.4. The method of claim 1 , wherein said first volume of polyethyleneimine and/or said second volume of polyethyleneimine has a molecular weight of approximately 400 to 200 claim 1 ,000.5. A system for separating a nucleic acid material from a fluid claim 1 , said system comprising:a positively charged polymer which is operative to bind said nucleic acid material; anda releasing agent, said releasing agent comprising a solution of an alkaline material and a glycol, said solution having a pH of no more than 12, said agent being operative to cause said nucleic acid material to be released from said polymer.6. The system of claim 5 , wherein said polyethyleneimine derivatized solid matrix material comprises a carboxylated ...

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Номер записи: 5
22-08-2013 дата публикации

Precursors for the polymer-assisted deposition of films

Номер: US20130217840A1
Автор: Burrell Anthony K., Jia Quanxi, Lin Yuan, McCleskey Thomas M.
Принадлежит:

A polymer assisted deposition process for deposition of metal oxide films is presented. The process includes solutions of one or more metal precursor and soluble polymers having binding properties for the one or more metal precursor. After a coating operation, the resultant coating is heated at high temperatures to yield metal oxide films. Such films can be epitaxial in structure and can be of optical quality. The process can be organic solvent-free. 110-. (canceled)11. A composition of matter comprising a solution of at least two metal precursors , ethylenediaminetetraacetic acid or salts of ethylenediaminetetraacetic acid , and a soluble polymer selected from the group consisting of polyethylenimine , carboxylated polyethylenimine , polypyrolidone , and poly(ethylene-maleic acid) , said polymer characterized as having binding properties for said at least two metal precursors , wherein the binding constant for the polymer-metal complex interaction is greater than about 10000 molL , said at least two metal precursors are present in a pre-selected ratio , wherein said at least two metals are selected from the group consisting of lanthanide metals.1214-. (canceled)15. A composition of matter comprising a solution of at least two metal precursors , ethylenediaminetetraacetic acid or salts of ethylenediaminetetraacetic acid , and a soluble polymer selected from the group consisting of polyethylenimine , carboxylated polyethylenimine , polypyrolidone , and poly(ethylene-maleic acid) , said polymer characterized as having binding properties for said at least two metal precursors , wherein the binding constant for the polymer-metal complex interaction is greater than about 10000 molL , said at least two metal precursors are present in a pre-selected ratio , wherein said at least two metals are indium and tin.16. A composition of matter comprising a solution of at least two metal precursors , ethylenediaminetetraacetic acid or salts of ethylenediaminetetraacetic acid , and ...

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Номер записи: 6
14-11-2013 дата публикации

CROSSLINKED POLYMERS CONTAINING BIOMASS DERIVED MATERIALS

Номер: US20130303705A1
Автор: ANDREWS MARK ALLEN, Chenault Henry Keith, Figuly Garret D.
Принадлежит:

Novel, crosslinked polymers using biomass derived materials, such as aldaric acids and derivatives, are provided. The polymers can be used as hydrogels and in antimicrobial compositions. 2. The crosslinked polymer of wherein the repeat units comprise aliphatic hydrocarbylene groups having substituents comprising one or more of C1-C22 aminoalkyl groups claim 1 , —COOZ claim 1 , —COX claim 1 , —CONZZ′ claim 1 , or —CONH(CH2)pNH2 claim 1 , and salts thereof.4. The crosslinked polymer of either or wherein at least one repeat unit contains one or more substituents comprising one or more of C1-C22 aminoalkyl groups claim 1 , optionally substituted with alkyl or aldaroyl groups claim 1 , or a salt thereof.5. The crosslinked polymer of wherein the polymer is a derivative of polyallylamine claim 1 , polyallylamine hydrochloride claim 1 , branched polyethyleneimine claim 1 , branched polyethyleneimine hydrochloride claim 1 , poly(acryloyl chloride) claim 1 , poly(methacryloyl chloride) claim 1 , poly[N-(□-aminoalkyl)acrylamide] claim 1 , polyglycosamine claim 1 , carboxymethylchitosan claim 1 , chitosan claim 1 , chitosan hydrochloride claim 1 , or a derivative or salt thereof.6. The crosslinked polymer of wherein the aldaroyl moiety in the crosslinking unit is glucaroyl claim 1 , galactaroyl claim 1 , mannaroyl claim 1 , xylaroyl claim 1 , or tartaroyl.8. The crosslinked polymer of wherein the suitable functional group is derived from an amine claim 7 , hydroxyl claim 7 , carboxylic acid claim 7 , ester claim 7 , urethane claim 7 , urea claim 7 , amide claim 7 , or isocyanate; and G is an epoxide claim 7 , isocyanate claim 7 , benzylic halide claim 7 , amine claim 7 , acid halide claim 7 , ester claim 7 , or amide.9. The crosslinked polymer of wherein L and L′ are independently selected from —Y—R claim 7 , wherein Y is O claim 7 , NH claim 7 , or S and R is alkyl claim 7 , substituted alkyl claim 7 , alkaryl claim 7 , substituted alkaryl claim 7 , aryl claim 7 , or ...

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Номер записи: 7
26-12-2013 дата публикации

Hole transport compositions and related devices and methods (ii)

Номер: US20130344648A1
Автор: Brian Woodworth, Christopher Knittel, Christopher T. Brown, Jing Wang, Mathew Mathai, Neetu Chopra, Venkataramanan Seshadri
Принадлежит: Plextronics Inc

A composition comprising: at least one compound comprising a hole transporting core, wherein the core is covalently bonded to a first arylamine group and also covalently bonded to a second arylamine group different from the first, and wherein the compound is covalently bonded to at least one intractability group, wherein the intractability group is covalently bonded to the hole transporting core, the first arylamine group, the second arylamine group, or a combination thereof, and wherein the compound has a molecular weight of about 5,000 g/mole or less. Blended mixtures of arylamine compounds, including fluorene core compounds, can provide good film formation and stability when coated onto hole injection layers. Solution processing of OLEDs is a particularly important application.

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Номер записи: 8
07-01-2021 дата публикации

METHOD FOR PRODUCING A POLYURETHANE POLYMER

Номер: US20210002198A1
Автор: Chen Hong, Xie Chunping, Zhao Xiaodong, Zhou Zhaolin
Принадлежит:

A method for producing a polyurethane polymer comprises the steps of: (a) providing a polyol composition, the polyol composition comprising (i) a polyol, (ii) a polyethylenimine compound; and (iii) a bisulfite compound, (b) providing an isocyanate compound; (c) providing a catalyst; (d) combining and reacting the polyol composition, the isocyanate compound, and the catalyst to produce a polyurethane polymer. 125-. (canceled)26. A method for producing a polyurethane polymer comprising the steps of: (i) a polyol,', '(ii) a polyethylenimine compound; and', '(iii) a bisulfite compound;, '(a) providing a polyol composition, the polyol composition comprising(b) providing an isocyanate compound;(c) providing a catalyst;(d) combining and reacting the polyol composition, the isocyanate compound, and the catalyst to produce a polyurethane polymer.27. The method of claim 26 , wherein the polyol has a molar mass of about 400 g/mol or more.28. The method of claim 26 , wherein the polyol is a polyether polyol.29. The method of claim 26 , wherein the polyethylenimine compound has a molar mass of about 500 g/mol or more.30. The method of claim 26 , wherein the polyethylenimine compound preferably is present in the polyol composition in an amount of about 50 ppm or more claim 26 , based on the weight of the polyol present in the polyol composition31. The method of claim 30 , wherein the polyethylenimine compound preferably is present in the polyol composition in an amount of about 50 ppm to about 3 claim 30 ,000 ppm claim 30 , based on the weight of the polyol present in the polyol composition32. The method of claim 26 , wherein the bisulfite compound is present in the polyol composition in an amount of about 50 ppm or more claim 26 , based on the weight of the polyol present in the polyol composition.33. The method of claim 32 , wherein the bisulfite compound is present in the polyol composition in an amount of about 50 ppm to about 3 claim 32 ,000 ppm claim 32 , based on the ...

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Номер записи: 9
03-01-2019 дата публикации

FREE-STANDING NON-FOULING POLYMERS, THEIR COMPOSITIONS, AND RELATED MONOMERS

Номер: US20190002625A1
Автор: BAI Tao, Ella-Menye Jean-René, Hung Hsiang-Chieh, Jain Priyesh, Jiang Shaoyi, LI YANG, Sinclair Andrew, Sundaram Harihara Subramanian, Zhang Peng
Принадлежит: UNIVERSITY OF WASHINGTON

Free-standing non-fouling polymers and polymeric compositions, monomers and macromonomers for making the polymers and polymeric compositions, objects made from the polymers and polymeric compositions, and methods for making and using the polymers and polymeric compositions. 119-. (canceled)2122-. (canceled)23. A polymer of having a fibrinogen binding level of less than 30 ng/cmin a fibrinogen binding assay (polymer surface is incubated at 37° C. for 90 minutes with a 1.0 mg/mL fibrinogen solution in 0.15 M phosphate buffered saline at pH 7.4).24. A polymer of having a tensile or compressive strength greater than 0.5 MPa.25. A polymer of having a fibrinogen binding level of less than 30 ng/cmin a fibrinogen binding assay (polymer surface is incubated at 37° C. for 90 minutes with a 1.0 mg/mL fibrinogen solution in 0.15 M phosphate buffered saline at pH 7.4) and a tensile or compressive strengths greater than 0.5 MPa.26. A polymer of claim 20 , wherein the polymer is crosslinked.27. A composite claim 20 , comprising a polymer of and a second polymer.28. The composite of claim 27 , wherein the second polymer is selected from the group consisting of polyesters claim 27 , polycarbonates claim 27 , polyurethanes claim 27 , polyureas claim 27 , polysulfides claim 27 , polysulfones claim 27 , polyimides claim 27 , polyepoxies claim 27 , aromatic polyesters claim 27 , cellulosics claim 27 , fluoropolymers claim 27 , polyacrylics claim 27 , polyamides claim 27 , polyanhydrides claim 27 , polyethers claim 27 , vinyl polymers claim 27 , phenolics claim 27 , elastomers claim 27 , and other addition polymers.29. The composite of further comprising a strength additive.30. The composite of further comprising a strength additive selected from the groups consisting of fiber claim 27 , clays claim 27 , nanotubes claim 27 , and other inorganic objects.31. A polymer of formed into an object by a method selected from the group consisting of injection molding claim 20 , blow molding claim ...

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Номер записи: 10
13-01-2022 дата публикации

BINDERS

Номер: US20220010067A1
Автор: Pacorel Benedicte
Принадлежит:

The present invention relates to binder compositions with improved amine components, and a method of manufacturing a collection of matter bound by said binder compositions. 1. A binder composition comprising a polymeric product of at least one carbohydrate component and at least one amine component , wherein the at least one amine component comprises a substituted or unsubstituted primary diamine and/or a substituted or unsubstituted primary triamine.2. The binder composition according to claim 1 , wherein the polymeric product is a product of the at least one carbohydrate component claim 1 , the at least one amine component claim 1 , and at least one additional crosslinker which is different from the amine component.3. The binder composition according to claim 1 , wherein the substituted or unsubstituted primary diamine is a compound wherein the amino groups are separated in the molecule by a spacer group having a length of 4 to 12 atoms.4. The binder composition according to claim 3 , wherein the substituted or unsubstituted primary diamine is a compound wherein the amino groups are separated in the molecule by a spacer group having a length of 6 to 8 atoms.5. The binder composition according to claim 3 , wherein the primary diamine further contains at least one substituent within the spacer group.6. The binder composition according to claim 1 , wherein the substituted or unsubstituted primary triamine is a compound wherein at least two of the primary amino groups are separated in the molecule by a spacer group having a length of 4 to 12 atoms.7. The binder composition according to claim 6 , wherein the substituted or unsubstituted primary triamine is a compound wherein at least two of the primary amino groups are separated in the molecule by a spacer group having a length of 6 to 8 atoms.8. The binder composition according to claim 1 , wherein the at least one carbohydrate component is selected from the group consisting of monosaccharides claim 1 , disaccharides ...

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Номер записи: 11
11-01-2018 дата публикации

POLYMERIC AMINE BASED CARBON DIOXIDE ADSORBENTS

Номер: US20180008958A1
Автор: CHOI Min Kee, CHOI Woo Sung
Принадлежит:

Carbon dioxide adsorbents are provided. The carbon dioxide adsorbents include a polymeric amine and a porous support on which the polymeric amine is supported. the polymeric amine consists of a polymer skeleton containing nitrogen atoms and branched chains bonded to the nitrogen atoms of the polymer skeleton. Each of the branched chains contains at least one nitrogen atom. the polymeric amine is modified by substitution of at least one of the nitrogen atoms of the polymer skeleton or the branched chains with a hydroxyl group-containing carbon chain. 1. A carbon dioxide adsorbent comprising: a polymeric amine consisting of a polymer skeleton containing nitrogen atoms and branched chains bonded to the nitrogen atoms of the polymer skeleton , each branched chain containing at least one nitrogen atom; and a porous support on which the polymeric amine is supported , wherein the polymeric amine is modified by substitution of at least one of the nitrogen atoms of the polymer skeleton or the branched chains with a hydroxyl group-containing carbon chain.2. The carbon dioxide adsorbent according to claim 1 , wherein the polymeric amine has a polyalkyleneimine basic structure.3. The carbon dioxide adsorbent according to claim 1 , wherein the polymeric amine has a polyethyleneimine basic structure.4. The carbon dioxide adsorbent according to claim 1 , wherein the polymer skeleton has a repeating unit structure represented by —[(CH)—NR]— (where R is hydrogen or a branched chain claim 1 , x is from 2 to 6 claim 1 , and y representing the average number of repeating units in the linear polyalkyleneimine chain is from 5 to 100) and the branched chain has an alkyleneamine structure represented by —(CH)—NHor an alkyleneimine structure represented by —(CH)—NR′(where one of the R's is an alkyleneamine or alkyleneimine group and the other R′ is hydrogen claim 1 , an alkyleneamine group or an alkyleneimine group).5. The carbon dioxide adsorbent according to claim 1 , wherein the hydroxyl ...

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Номер записи: 12
08-01-2015 дата публикации

Antipathogenic Guanidinium Copolymer

Номер: US20150011716A1
Автор: LOMBARDI JOHN L.
Принадлежит:

An antipathogenic copolymer 122, formed by the process of heating hexamethylenediamine HMDA 102, bis(hexamethylene)triamine BHMT 104, guanidinium hydrochloride 106. 1. An antipathogenic copolymer , formed by the process of heating hexamethylenediamine , bis(hexamethylene)triamine , and guanidinium hydrochloride.13. An antipathogenic copolymer , formed by the process of heating:bis(hexamethylene)triamine;guanidinium hydrochloride; anda trifunctional, tri-amino-capped, polyether. Applicant's invention relates to a guanidinium polymer that is effective as a broad-spectrum disinfectant capable of immobilizing and/or killing pathogens, including active bacteria and dormant bacteria spores.The presence of certain types of bacteria and other pathogens, whether airborne or on exposed surfaces, creates a health risk. These pathogens may be naturally occurring in the environment or may be introduced by a sick or infected personal or animal. The risk of harm from pathogens is particularly a concern in healthcare settings, such a hospitals and nursing homes, where individuals are more likely to have weakened immune systems. Certain pathogens may be “weaponized,” and used as biological agents against both civilian and military personnel. These include anthrax () and ().To minimize the risk of harm as a result of exposure to bacteria, it has been a goal to develop substances and/or treatments that are effective in reducing or eliminating harmful bacteria. For instance, disinfectants are commonly applied to surfaces (i.e., floors, walls, work surfaces, and the like) to reduce or eliminate any exposed bacteria. These disinfectants, however, generally reside only on the surface and are, as such, easily washed away or otherwise removed. Such disinfectants must be periodically reapplied to maintain their effectiveness.Bacteria exist in either an active or a dormant state. In the active state, often referred to as the “vegetative state,” the bacteria is capable of growing and ...

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Номер записи: 13
26-01-2017 дата публикации

COMPOSITIONS FOR INTRODUCING RNA INTO CELLS

Номер: US20170021036A1
Автор: Dohmen Christian, Koch Christian, Plank Christian, Rudolph Carsten
Принадлежит:

The present invention relates to oligomers, polymers and lipidoids comprising characteristic oligo(alkylene amine) moieties which are useful as vehicles for transfecting a cell with RNA. The present invention furthermore relates to a composition comprising at least a nucleic acid and an oligomer or polymer or a lipidoid comprising such oligo(alkylene amine) moieties and to a method of transfecting a cell using said composition. Furthermore, the present invention relates to pharmaceutical compositions and uses. 2. The composition of claim 1 , comprising the RNA and the component comprising an oligo(alkylene amine) selected from components a) and b) claim 1 , wherein: {'br': None, 'sup': 2', '3', '4', '5', '6, 'sub': 2', '2', 'a', '2', '2', 'b', 'm', '2', '2', 'a', 'n, '—NR{CH—(CH)—NR—CH—(CH)—NR}—[CH—(CH)—NR]—R\u2003\u2003(IIa),'}, 'component a) is an oligomer or polymer comprising a plurality of groups of formula (IIa) as a side chain and/or as a terminal group{'sup': 2', '6, 'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'wherein a, b, m, n, and Rto Rare defined as in , and wherein one or more of the nitrogen atoms indicated in formula (IIa) may be protonated to provide a cationic oligomer or polymer structure; and'} {'br': None, 'sup': 2', '3', '4', '4', '6, 'sub': 2', '2', 'a', '2', '2', 'b', 'm', '2', '2', 'a', 'n, '—NR{CH—(CH)—NR—CH—(CH)—NR}—[CH—(CH)—NR]—R\u2003\u2003(IIIa),'}, 'component b) is an oligomer or polymer comprising a plurality of groups of formula (IIIa) as repeating units{'sup': 2', '5, 'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'wherein a, b, m, n, and Rto Rare defined as in , and wherein one or more of the nitrogen atoms indicated in formula (IIIa) may be protonated to provide a cationic oligomer or polymer structure.'}3. The composition of claim 1 , comprising the RNA and a lipidoid having the structure of formula (IVa):{'br': None, 'sup': 1', '2', '3', '4', '5', '6, 'sub': 2', '2', 'a', '2', '2', 'b', 'm', '2', '2', 'a', 'n, 'R—NR{CH—( ...

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Номер записи: 14
25-01-2018 дата публикации

HYPERBRANCHED POLYMERS AND POLYPLEXES AND DNA OR RNA DELIVERY SYSTEMS INCLUDING THE SAME

Номер: US20180021441A1
Автор: Ma Peter X., ZHANG Xiaojin
Принадлежит:

A hyperbranched polymer includes a hyperbranched, hydrophobic molecular core, respective low molecular weight polyethyleneimine chains attached to at least three branches of the hyperbranched, hydrophobic molecular core, and respective polyethylene glycol chains attached to at least two other branches of the hyperbranched, hydrophobic molecular core. Examples of the hyperbranched polymer may be used to form hyperbranched polyplexes, and may be included in DNA or RNA delivery systems. 1. A hyperbranched polymer , comprising:a hyperbranched, hydrophobic molecular core;respective low molecular weight polyethyleneimine chains attached to two or more branches of the hyperbranched, hydrophobic molecular core; andrespective polyethylene glycol chains attached to two or more other branches of the hyperbranched, hydrophobic molecular core.2. The hyperbranched polymer as defined in wherein the hyperbranched claim 1 , hydrophobic molecular core is a hyperbranched polyester including at least 4 terminal hydroxyl groups.3. The hyperbranched polymer as defined in wherein the low molecular weight polyethyleneimine chains each have a molecular weight ranging from about 400 g/mol to about 5 claim 1 ,000 g/mol.4. A linear polymer claim 1 , comprising:a polyethylene glycol chain;a polyester chain attached to an end of the polyethylene glycol chain; andrespective low molecular weight polyethyleneimine chains attached as side chains to the polyester chain.5. The linear polymer as defined in wherein the polyester chain is selected from the group consisting of polylactide claim 4 , polycaprolactone claim 4 , polycarbonate claim 4 , poly(phosphoesters) claim 4 , polyanhydrides claim 4 , and polyglycolic acid.6. The linear polymer as defined in wherein the low molecular weight polyethyleneimine chains each have a molecular weight ranging from about 400 g/mol to about 5 claim 4 ,000 g/mol.7. A hyperbranched polyplex claim 4 , comprising:a hydrophilic inner section formed of a first plurality ...

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Номер записи: 15
28-01-2016 дата публикации

Use of polypropyleneimine as curing agent for epoxide resins

Номер: US20160024344A1
Автор: Achim Kaffee, Alexander Panchenko, Andreas Kunst, Ansgar Gereon Altenhoff, Christian Mueller, Christoph Mueller, Kirsten Dahmen, Michael Henningsen, Monika CHARRAK
Принадлежит: BASF SE

The present invention relates to the use of substantially linear polypropyleneimine as a hardener for epoxy resins, and also to a corresponding curable composition, to the curing thereof, and to the cured epoxy resin obtainable therefrom.

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Номер записи: 16
29-01-2015 дата публикации

METHOD AND FILTER FOR REMOVING NITRATE IONS

Номер: US20150027949A1
Автор: Dong Hongchen, Lewis Larry Neil, Vasconcellos Stephen Robert
Принадлежит: GENERAL ELECTRIC COMPANY

A method for removing nitrate ions from a solution is presented. The method includes providing a polymer comprising a protonated amine moiety and an anion derived from an acid having a pKa value greater than about 1. The method further includes contacting the polymer with the solution to bind at least a portion of the nitrate ions in the solution with the polymer, and form a polymer-nitrate complex. The method furthermore includes separating at least a portion of the polymer-nitrate complex from the solution. 1. A method for removing nitrate ions from a solution , comprising a protonated amine moiety; and', 'an anion derived from an acid having a pKa value greater than about 1;, '(i) providing a polymer comprising(ii) contacting the polymer with the solution to bind at least a portion of the nitrate ions in the solution with the polymer, and form a polymer-nitrate complex; and(iii) separating at least a portion of the polymer-nitrate complex from the solution.2. The method of claim 1 , wherein the polymer comprises a primary protonated amine moiety claim 1 , a secondary protonated amine moiety claim 1 , a tertiary protonated amine moiety claim 1 , or combinations thereof.3. The method of claim 1 , wherein the polymer comprises a protonated poly(vinyl amine) claim 1 , a protonated poly(4-vinyl pyridine) claim 1 , a protonated polyethyleneimine claim 1 , a protonated poly(2-(dimethylamino)ethyl methacrylate) claim 1 , a protonated poly(amido amine) dendrimer claim 1 , or combinations thereof.4. The method of claim 1 , wherein the polymer comprises a protonated polyethyleneimine.5. The method of claim 1 , wherein the polymer comprises a branched protonated polyethyleneimine6. The method of claim 1 , wherein the anion is derived from an acid having a pKa value greater than about 4.7. The method of claim 1 , wherein the anion is derived from an acid selected from the group consisting of acetic acid claim 1 , propionic acid claim 1 , butyric acid claim 1 , chloroacetic ...

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Номер записи: 17
03-03-2022 дата публикации

POLYETHYLENIMINE AS A NEW EMULSION BREAKER FOR QUENCH WATER SYSTEMS

Номер: US20220062793A1
Автор: CUOQ Fabrice, LEEN Steven
Принадлежит: Sabic Global Technologies B.V.

Methods to increase the efficiency and throughput of hydrocarbon stream cracking by inhibiting the formation of, or resolving an emulsion, in an ethylene production quench water system. The method includes contacting a non-alkoxylated branched or linear polyethylenimine (PEI) with a quench water composition from the quench water system under conditions suitable to prevent the formation of an emulsion or to resolve the quench water composition into two immiscible phases. 1. A method of inhibiting the formation of , or resolving an emulsion , in an ethylene production quench water system , the method comprising contacting a non-alkoxylated branched or linear polyethylenimine (PEI) with a quench water composition from the quench water system under conditions suitable to prevent the formation of an emulsion or to resolve the quench water composition into two immiscible phases.2. The method of claim 1 , wherein the PEI comprises a molecular weight of 100 to 800 claim 1 ,000 g/mol claim 1 , 100 to 750 claim 1 ,000 g/mol claim 1 , 100 to 1300 g/mol g/mol claim 1 , or 100 to 800 g/mol.3. The method of claim 1 , wherein the quench water composition comprises 0.01 to 30 ppm claim 1 , preferably 0.01 to 10 ppm of the PEI.6. The method of claim 1 , wherein the quench water system further comprises one or more of a Quench Water Tower (QWT) claim 1 , a Quench Water Loop (QWL) claim 1 , or a Quench Water Settler (QWS).7. The method of claim 6 , wherein the method comprises adding the PEI to a feed of the QWT claim 6 , a feed of the QWL claim 6 , a feed of the QWS claim 6 , or any combination thereof.8. The method of claim 6 , wherein the QWT comprises a temperature of 25 to 150° C.9. The method of claim 1 , wherein the quench water composition comprises gasoline hydrocarbons.10. The method of claim 1 , wherein one of the two immiscible phases is an aqueous phase.11. The method of any one of claim 10 , further comprising providing the aqueous phase to a process water stripper (PWS ...

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Номер записи: 18
26-02-2015 дата публикации

Explosive Detection Polymer Comprising Functionalized Polyamine Polymers and Methods of Using the Same

Номер: US20150056711A1
Автор: Lei Yu, Wang Ying
Принадлежит: University of Connecticut

Explosives detection polymers are provided that include a polyamine polymer, such as polyethylenimine, functionalized with a small molecule fluorophore. Methods for detecting an explosive material using polyamine polymers functionalized with a small molecule fluorophore are also provided. Sensors for explosive detection are provided that include a polyamine polymer functionalized with a small molecule fluorophore and a complementary analytical device. 1. An explosives detecting polymer comprising a polyamine polymer functionalized with a small molecule fluorophore.2. The polymer of claim 1 , wherein the small molecule fluorophore comprises an aromatic multi-ring hydrocarbon claim 1 , an aromatic multi-ring heterocycle claim 1 , or a mixture thereof.3. The polymer of claim 1 , wherein the polyamine polymer is selected from the group consisting of polyethylenimine claim 1 , polyvinyl amine claim 1 , polyallylamine and polylysine.5. The polymer of claim 4 , wherein{'sub': C', '2-4, 'Ris a hydrogen or —C(O)—Calkyl-;'}{'sub': 'B', 'Ris selected from the group consisting of a bond and hydrogen; and'}each n is selected independently from 2-6.6. The polymer of claim 4 , wherein{'sub': C', '3, 'Ris hydrogen or —C(O)—Calkyl-;'}{'sub': 'B', 'Ris hydrogen; and'}n is 2, 3 or 6.7. The polymer of claim 1 , wherein the small molecule fluorophore is selected from pyrene claim 1 , 1-pyrenebutyric acid claim 1 , pyrene-1-boronic acid claim 1 , 1-pyrenebutyric acid N-hydroxysuccinimide ester claim 1 , 5-carboxy-2 claim 1 ,7-dichlorofluorescein; 5-Carboxyfluorescein (5-FAM); 5(6)-carboxyfluorescein-N-hydroxysuccinimide ester (C1609); 5-HAT (Hydroxy Tryptamine); 5-Hydroxy Tryptamine (HAT); 6-Carboxyrhodamine 6G; 6-CR 6G; 6-JOE; Acridine Orange+DNA; Acriflavin; Alexa Fluor 430™; Alexa Fluor 488™; Alexa Fluor 500™; APTRA-BTC=Ratio Dye claim 1 , Zn; bis-BTC=Ratio Dye claim 1 , Zn; APTS; AmCyan; Astrazon Orange R; Aurophosphine; BCECF (high pH); Beta Lactamase; Bodipy 492/515; Bodipy 500/510 ...

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Номер записи: 19
01-03-2018 дата публикации

Ionically Crosslinked Polyelectrolytes as Underwater Adhesives and Controlled Release Vehicles

Номер: US20180055942A1
Автор: Huang Yan, Lapitsky Yakov
Принадлежит: The University of Toledo

Underwater adhesive materials, methods of making the same, and methods of using the same are described. 1. A method for controllably releasing a small molecule comprising:adding a small molecule to either (i) a first solution comprising non-polysaccharide polymer having two or more amine groups, or (ii) a second solution comprising a multivalent phosphate crosslinker;mixing the first solution with the second solution, at a pH ranging from about 4 to about 10, to form an adhesive gel; andapplying the adhesive gel to a target location, wherein the small molecule is released from the adhesive gel over a period of time.2. A method of delivering an adhesive to a target location comprising:mixing a polyamine with a multivalent phosphate crosslinker in acidic or basic solution to obtain a mixture;injecting the mixture to a target location; andadjusting the pH of the mixture to ambient pH to form an adhesive gel-like complex in the target location.3. The method of claim 2 , further comprising adjusting the pH to an acidic or basic pH to dissolve the adhesive gel.4. A method of delivering an adhesive to a target location comprising:mixing a polyamine with a multivalent phosphate crosslinker in a solution to obtain a mixture;injecting the mixture to a target location; andadjusting the ionic strength of the solution to form an adhesive gel-like complex in the target location.5. The method of claim 4 , further comprising adjusting the pH to an acidic or basic pH to dissolve the adhesive gel.6. A composition comprising:a non-polysaccharide polymer having two or more amine groups; anda multivalent phosphate crosslinker;the composition comprising an ionically crosslinked network that forms a gel-like coacervate at a pH in the range of from about 4 to about 10.7. The composition of claim 6 , wherein the multivalent phosphate crosslinker is selected from the group consisting of a tetravalent phosphate and a pentavalent phosphate.8. The composition of claim 6 , wherein the ...

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Номер записи: 20
04-03-2021 дата публикации

MULTI-ARMED POLYMERS COMPRISING FREE-RADICAL-POLYMERIZABLE MONOMERS AND COMPOSITIONS, SYSTEMS AND METHODS PERTAINING TO THE SAME

Номер: US20210061950A1
Автор: Delaney, Dyndikova Tatyana, JR. Joseph T., KUMMAILIL John, Rehder Carey
Принадлежит:

In some aspects, the present disclosure pertains to multi-arm polymers that comprise a core, a plurality of polymer segments having a first end that is covalently attached to the core and a second end comprising a moiety that comprises a reactive group, wherein the polymer segments comprise one or more free-radical-polymerizable monomers. In some aspects, systems are provided that comprise a first composition comprising such a multi-arm polymer and a second composition comprising a multifunctional compound that comprises functional groups that are reactive with the reactive groups of the multi-arm polymer. In some aspects, systems are provided that comprise crosslinked reaction products of such a multi-arm polymer and such a multifunctional compound. 1. A multi-arm polymer comprising a core , a plurality of polymer segments having a first end that is covalently attached to the core and a second end comprising a moiety that comprises a reactive group , wherein the polymer segments comprise one or more free-radical-polymerizable monomers.2. The multi-arm polymer of claim 1 , wherein the polymer segments comprise one or more hydrophilic aprotic monomers.3. The multi-arm polymer of claim 1 , wherein the polymer segments comprise one or more monomers selected from N-vinyl pyrrolidone claim 1 , hydroxyethyl acrylate claim 1 , hydroxyethyl methacrylate claim 1 , PEG methyl ether acrylate and PEG methyl ether methacrylate.4. The multi-arm polymer of claim 1 , wherein the core is a polyol residue core.5. The multi-arm polymer of claim 1 , wherein the reactive group is an electrophile.6. The multi-arm polymer of claim 1 , wherein the reactive group is selected from N-hydroxysuccinimide esters claim 1 , imidazole esters claim 1 , imidazole carboxylates and benzotriazole esters.7. The multi-arm polymer of claim 1 , wherein the reactive group is a nucleophile.8. The multi-arm polymer of claim 1 , wherein the reactive group is an amine group.9. The multi-arm polymer of claim 1 , ...

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Номер записи: 21
04-03-2021 дата публикации

USE OF POLYAMINES AS RESOLVING AGENTS FOR CAPILLARY ELECTROPHORESIS OF LABELED GLYCANS USING GELS

Номер: US20210063347A1
Автор: HAXO Francis T., KIMZEY Michael J., LIMJAP Fielito U.
Принадлежит: AGILENT TECHNOLOGIES, INC.

The present disclosure provides methods of improving the resolution of labeled glycans in capillary electrophoresis techniques using a gel as a sieving matrix, by incorporating polyamines in the gel. 21. The method of method , wherein said polyamine is of Structure 4 and is 1 ,4 ,7-Trimethyl-1 ,4 ,7-triazacyclononane.3. The method of claim 1 , wherein said polyamine is of Structure 1 and is 1 claim 1 ,2-Ethanediamine claim 1 , N1-(2-aminoethyl) or 1 claim 1 ,2-Ethanediamine claim 1 , N1-[2-(dimethylamino) ethyl]-N1 claim 1 , N2 claim 1 , N2-trimethyl-.4. The method of claim 3 , wherein said polyamine is 1 claim 3 ,2-Ethanediamine claim 3 , N1-[2-(dimethylamino) ethyl]-N1 claim 3 , N2 claim 3 , N2-trimethyl-.5. The method of claim 1 , wherein said polyamine is of Structure 2 claim 1 , and is N claim 1 ,N claim 1 ,N′ claim 1 ,N′-Tetramethyl-1 claim 1 ,3-propanediamine6. The method of claim 1 , wherein said glycans have been labeled by being reacted with 8-aminopyrene-1 claim 1 ,3 claim 1 ,6-trisulfonic acid (“APTS”) claim 1 , InstantQ™ claim 1 , or 8-Aminonaphthalene-1 claim 1 ,3 claim 1 ,6-trisulfonic acid disodium salt (“ANTS”).7. The method of claim 6 , wherein the glycans have been labeled with APTS and are MAN-5 glycan and A1F.8. (canceled)9. The method of claim 6 , wherein the glycans have been labeled with InstantQ™ and are MAN-5 glycan and A1F.10. (canceled)12. The composition of claim 11 , wherein said polyamine is of Structure 4 and is 1 claim 11 ,4 claim 11 ,7-Trimethyl-1 claim 11 ,4 claim 11 ,7-triazacyclononane.13. The composition of claim 11 , wherein said polyamine is of Structure 1 and is 1 claim 11 ,2-Ethanediamine claim 11 , N1-(2-aminoethyl) or 1 claim 11 ,2-Ethanediamine claim 11 , N1-[2-(dimethylamino) ethyl]-N1 claim 11 , N2 claim 11 , N2-trimethyl-.14. The composition of claim 11 , wherein said polyamine is N claim 11 ,N claim 11 ,N′ claim 11 ,N″ claim 11 ,N″-Pentamethyldiethylenetriamine or N claim 11 ,N claim 11 ,N′ claim 11 ,N′-Tetramethyl-1 ...

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Номер записи: 22
15-03-2018 дата публикации

STABLE VIOLET-BLUE TO BLUE IMIDAZOLIUM COMPOUNDS

Номер: US20180072970A1
Автор: Murphy Bryan Patrick, Zhang Guiru, ZHAO Jielu
Принадлежит:

Disclosed are novel stable violet-blue to blue imidazolium azo compounds that have a simplified chromophore and high relative solubility in aqueous systems, and that are stable under the conditions of use and storage. The compounds are useful for dyeing fibers such as fabrics and hair, as fabric hueing agents, and as dyes for other keratinaceous materials. Also disclosed are laundry care compositions comprising the imidazolium azo compounds and methods of using the compositions. 2. A compound according to wherein at least one of X and Y is an oxygen atom.3. A compound according to wherein X and Y are both oxygen atoms.4. A compound according to wherein R claim 3 , R claim 3 , Rand Rare each independently alkenyl claim 3 , alkyl claim 3 , aminoalkyl or alkyl group carrying a quaternary ammonium cation.5. A compound according to claim 1 , wherein the compound is attached to a polymer backbone through R claim 1 , R claim 1 , Ror R.7. A compound according to claim 6 , wherein Rand Rare each independently alkyl claim 6 , aminoalkyl or alkyl group carrying a quaternary ammonium cation.8. A compound according to claim 7 , wherein Ris alkyl and Ris aminoalkyl or an alkyl group carrying a quaternary ammonium cation.9. A compound according to claim 6 , wherein Rand Rare both an alkyl group carrying a quaternary ammonium cation.10. A compound according to claim 6 , wherein Rand Rare each independently hydrogen claim 6 , alkenyl claim 6 , alkyl claim 6 , aminoalkyl or an alkyl group carrying a quaternary ammonium cation.11. A compound according to claim 10 , wherein Ris hydrogen or alkyl and Ris alkenyl or alkyl.12. A compound according to claim 6 , wherein the compound is attached to a polymer backbone through R claim 6 , R claim 6 , Ror R.13. A compound according to claim 6 , wherein X claim 6 , Y and Z are all carbon.14. A compound according to claim 13 , wherein Rand Rare each independently alkyl claim 13 , aminoalkyl claim 13 , alkyl group carrying a quaternary ammonium ...

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Номер записи: 23
24-03-2022 дата публикации

BINDERS

Номер: US20220089818A1
Автор: Pacorel Benedicte
Принадлежит:

The present invention relates to binder compositions with improved amine components, and a method of manufacturing a collection of matter bound by said binder compositions. 1. A binder composition comprising a polymeric product of at least one carbohydrate component and at least one amine component , wherein the at least one amine component comprises a substituted or unsubstituted primary diamine and/or a substituted or unsubstituted primary triamine.2. The binder composition according to claim 1 , wherein the polymeric product is a product of the at least one carbohydrate component claim 1 , the at least one amine component claim 1 , and at least one additional crosslinker which is different from the amine component.3. The binder composition according to claim 1 , wherein the substituted or unsubstituted primary diamine is a compound wherein the amino groups are separated in the molecule by a spacer group having a length of 4 to 12 atoms.4. The binder composition according to claim 3 , wherein the substituted or unsubstituted primary diamine is a compound wherein the amino groups are separated in the molecule by a spacer group having a length of 6 to 8 atoms.5. The binder composition according to claim 3 , wherein the primary diamine further contains at least one substituent within the spacer group.6. The binder composition according to claim 1 , wherein the substituted or unsubstituted primary triamine is a compound wherein at least two of the primary amino groups are separated in the molecule by a spacer group having a length of 4 to 12 atoms.7. The binder composition according to claim 6 , wherein the substituted or unsubstituted primary triamine is a compound wherein at least two of the primary amino groups are separated in the molecule by a spacer group having a length of 6 to 8 atoms.8. The binder composition according to claim 1 , wherein the at least one carbohydrate component is selected from the group consisting of monosaccharides claim 1 , disaccharides ...

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Номер записи: 24
24-03-2022 дата публикации

GAS BARRIER POLYMER AND GAS BARRIER LAMINATE USING SAME

Номер: US20220089825A1
Автор: MORIYA Eiichi, Odagawa Kenji, SUZUKI Shingo
Принадлежит: Mitsui Chemicals Tohcello, Inc.

A gas barrier polymer is formed by heat-curing a mixture including polycarboxylic acid and a polyamine compound, in which, in an infrared absorption spectrum, when a straight line connecting a measurement point at 1493 cmand a measurement point at 1780 cmis set as a baseline, an absorption intensity at 1660 cmis set as I(1660), and an absorption intensity at 1625 cmis set as I(1625), R represented by Equation (1) is greater than 1. 1. A gas barrier polymer formed by heat-curing a mixture including polycarboxylic acid and a polyamine compound ,{'sup': ['−1', '−1', '−1', '−1'], '#text': 'wherein, in an infrared absorption spectrum of the gas barrier polymer, when a straight line connecting a measurement point at 1493 cmand a measurement point at 1780 cmis set as a baseline, an absorption intensity at 1660 cmis set as I(1660), and an absorption intensity at 1625 cmis set as I(1625),'}{'claim-text': {'br': None, '#text': 'R=I(1660)/I(1625)−{−0.65×(total amine/COOH)+0.4225}\u2003\u2003(1)'}, '#text': 'R represented by Equation (1) is greater than 1,'}(in Equation (1), “total amine” is a total number of moles of primary, secondary, and tertiary amino groups included in the polyamine compound in the mixture, and “COOH” is the number of moles of —COOH groups included in the polycarboxylic acid in the mixture).2. The gas barrier polymer according to claim 1 ,wherein the polycarboxylic acid includes one or two or more polymers selected from the group consisting of polyacrylic acid, polymethacrylic acid, and a copolymer of acrylic acid and methacrylic acid.3. The gas barrier polymer according to or claim 1 ,wherein the polyamine compound includes a branched polyamine.4. The gas barrier polymer according to claim 1 ,wherein (total amine/COOH) in Equation (1) is equal to or more than 0.4 and equal to or less than 0.7.5. The gas barrier polymer according to claim 1 ,{'sub': '2', '#text': 'wherein (total of the number of moles of —NH groups and the number of moles of —NHgroups ...

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Номер записи: 25
05-03-2020 дата публикации

PREVENTION OF BIOFILM FORMATION

Номер: US20200071542A1
Автор: CAHAN Amos, Deligianni Hariklia, Ding Xin, Fevre Mareva B., Hedrick James L., HSUEH PEI-YUN S., Liang Zhen Chang, Park Nathaniel H., van Kessel Theodore G., Wojtecki Rudy J., Yang Yi Yan
Принадлежит:

Antibacterial coatings and methods of making the antibacterial coatings are described herein. A first branched polyethylenimine (BPEI) layer is formed and a first glyoxal layer is formed on a surface of the BPEI layer. The first BPEI layer and the first glyoxal layer are cured to form a crosslinked BPEI coating. The first BPEI layer can be modified with superhydrophobic moieties, superhydrophilic moieties, or negatively charged moieties to increase the antifouling characteristics of the coating. The first BPEI layer can be modified with contact-killing bactericidal moieties to increase the bactericidal characteristics of the coating. 1. An apparatus , the apparatus comprising:an implantable medical device; anda glyoxal-crosslinked branched polyethylenimine (BPEI) coating formed on a surface of the implantable medical device;wherein amines of the BPEI coating are covalently bonded to superhydrophobic moieties or negatively-charged moieties.2. The apparatus of claim 1 , wherein the implantable medical device further comprises a power source.3. The apparatus of claim 2 , wherein the power source is embedded within the implantable medical device.4. The apparatus of claim 3 , wherein the power source comprises a battery.5. The apparatus of claim 3 , wherein the power source comprises a microcapacitor coupled to the negatively charged coating through an electrode.6. The apparatus of claim 1 , wherein the implantable medical device is selected from the group consisting of a prosthetic heart valve claim 1 , a left ventricular assist device claim 1 , vascular stents claim 1 , vascular grafts claim 1 , a prosthetic joint claim 1 , a bone implant claim 1 , an implanted tooth claim 1 , an implanted pacemaker claim 1 , a pacemaker generator or wires claim 1 , an intravascular line claim 1 , a ventriculoperitoneal shunt claim 1 , a urinary catheter claim 1 , an eye implant claim 1 , an intracranial implant claim 1 , or a subcutaneous implant.7. The apparatus of further comprising ...

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Номер записи: 26
05-03-2020 дата публикации

PREVENTION OF BIOFILM FORMATION

Номер: US20200071543A1
Автор: CAHAN Amos, Deligianni Hariklia, Ding Xin, Fevre Mareva B., Hedrick James L., HSUEH PEI-YUN S., Liang Zhen Chang, Park Nathaniel H., van Kessel Theodore G., Wojtecki Rudy J., Yang Yi Yan
Принадлежит:

Antibacterial coatings and methods of making the antibacterial coatings are described herein. A first branched polyethylenimine (BPEI) layer is formed and a first glyoxal layer is formed on a surface of the BPEI layer. The first BPEI layer and the first glyoxal layer are cured to form a crosslinked BPEI coating. The first BPEI layer can be modified with superhydrophobic moieties, superhydrophilic moieties, or negatively charged moieties to increase the antifouling characteristics of the coating. The first BPEI layer can be modified with contact-killing bactericidal moieties to increase the bactericidal characteristics of the coating. 1. A method for forming a negatively charged polymer coating , the method comprising:providing a polymer; andfunctionalizing the polymer with a bio-compatible moiety comprising a negative Zeta potential.2. The method of claim 1 , wherein the polymer is hydroxyapatite or poly(3 claim 1 ,4-ethylenedioxythiophene) (PEDOT).3. The method of claim 1 , wherein the bio-compatible moiety is a carboxylate group.4. The method of claim 3 , wherein the carboxylate group is derived from dodecanedioic acid.5. The method of claim 1 , wherein the bio-compatible moiety is a polystyrene sulfonate group.6. The method of claim 1 , wherein the negatively charged polymer coating is formed on a surface of an implantable medical device.7. The method of claim 6 , wherein the implantable medical device is selected from the group consisting of a prosthetic heart valve claim 6 , a left ventricular assist device claim 6 , vascular stents claim 6 , vascular grafts claim 6 , a prosthetic joint claim 6 , a bone implant claim 6 , an implanted tooth claim 6 , an implanted pacemaker claim 6 , a pacemaker generator or wires claim 6 , an intravascular line claim 6 , a ventriculoperitoneal shunt claim 6 , a urinary catheter claim 6 , an eye implant claim 6 , an intracranial implant claim 6 , or a subcutaneous implant.8. The method of claim 1 , wherein the implantable medical ...

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Номер записи: 27
05-03-2020 дата публикации

COMPOUND COMPRISING POLYAMINE, ACIDIC AND BORON FUNCTIONALITIES AND ITS USE AS A LUBRICANT ADDITIVE

Номер: US20200071633A1
Автор: DOYEN Valérie, ROGUES DE FURSAC Isabelle
Принадлежит: TOTAL MARKETING SERVICES

A product resulting from the reaction of at least: a hydroxybenzoic acid, optionally substituted by a hydrocarbyl group, a boron compound, an amine component selected from a di-fatty-alkyl(ene) polyalkylamine composition including one or more polyalkylamines of formulae (I) or (II). A lubricant composition includes this product. Use of this product as a lubricant for two-stroke marine engines and four-stroke marine engines, more preferably two-stroke marine engines. 114-. (canceled)16. The product according to claim 15 , wherein the hydroxybenzoic acid claim 15 , optionally substituted by a hydrocarbyl group claim 15 , is selected from the group consisting of: mono-alk(en)yl substituted salicylic acids claim 15 , di-alk(en)yl substituted salicylic acids claim 15 , acid functionalized calixarenes and mixtures thereof.18. The product according to claim 17 , wherein X comprises from 12 to 40 carbon atoms.20. The product according to claim 19 , wherein the hydroxybenzoic acid compound is salicylic acid.21. The product according to claim 15 , wherein the boron compound is selected from the group consisting of: boric acid claim 15 , boric acid complexes claim 15 , boric oxide claim 15 , a trialkyl borate in which the alkyl groups comprise independently from 1 to 4 carbon atoms claim 15 , a C-Calkyl boronic acid claim 15 , a C-Cdialkyl boric acid claim 15 , a C-Caryl boric acid claim 15 , a C-Cdiaryl boric acid claim 15 , a C-Caralkyl boric acid claim 15 , a C-Cdiaralkyl boric acid claim 15 , and products deriving from these by substitution of an alkyl group by one or more alkoxy unit.22. The product according to claim 21 , wherein the boron compound is boric acid.23. The product according to claim 15 , wherein the polyalkylamine composition comprises at least 4% w/w of branched compounds of formula (I) or (II) claim 15 , with regards to the total weight of polyalkylamine compounds (I) and (II) in the composition claim 15 , branched compound signifying that:in formula (I), ...

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Номер записи: 28
15-03-2018 дата публикации

METHOD FOR MANUFACTURING FILLING PLANARIZATION FILM AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE

Номер: US20180076047A1
Автор: Inoue Koji, Kayaba Yasuhisa, Ono Shoko, Tanaka Hirofumi, WACHI Hiroko
Принадлежит: Mitsui Chemicals, Inc.

A method for manufacturing a filling planarization film, the method including: a first coating step of applying a first coating liquid, containing a polyamine and a first solvent, to a region including a recessed part of a member having the recessed part, to fill the first coating liquid into the recessed part; and a second coating step of applying a second coating liquid, containing an organic substance having two or more carboxyl groups and a second solvent having a boiling point of 200° C. or less and an SP value of 30 (MPa)or less, to the region including the recessed part of the member into which the first coating liquid has been filled. 1. A method for manufacturing a filling planarization film , the method comprising:a first coating step of applying a first coating liquid, containing a polyamine and a first solvent, to a region including a recessed part of a member having the recessed part, to fill the first coating liquid into the recessed part; and{'sup': '1/2', 'a second coating step of applying a second coating liquid, containing an organic substance having two or more carboxyl groups and a second solvent having a boiling point of 200° C. or less and an SP value of 30 (MPa)or less, to the region including the recessed part of the member into which the first coating liquid has been filled, to form a filling planarization film that planarizes the region including the recessed part of the member.'}2. The method for manufacturing a filling planarization film according to claim 1 , wherein the organic substance having two or more carboxyl groups is a divalent or higher-valent carboxylic acid.3. The method for manufacturing a filling planarization film according to claim 1 , wherein a content of the polyamine in the first coating liquid is from 1.0% by mass to 20% by mass.4. The method for manufacturing a filling planarization film according to claim 1 , wherein the first solvent has a boiling point of 200° C. or less and is hydrophilic.5. The method for ...

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Номер записи: 29
18-03-2021 дата публикации

Crosslinked poly(allylamine) polymer pharmaceutical compositions

Номер: US20210079144A1
Автор: Eric F. Connor, Gerrit Klaerner, Kalpesh N. Biyani, Matthew J. Kade, Paul H. Kierstead, Randi K. Gbur, Scott M. Tabakman, Son H. Nguyen
Принадлежит: Tricida Inc

Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of a target species from the gastrointestinal tract would provide physiological benefits.

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Номер записи: 30
12-06-2014 дата публикации

High Capacity Perchlorate-Selective Resins From Hyperbranched Macromolecules

Номер: US20140158630A1
Автор: Changjun Yu, Dennis P. Chen, Mamadou S. Diallo
Принадлежит: Aquanano LLC

A resin is provided for selectively binding to perchloride and related anions (e.g., TcO 4 − , ReO 4 − and I − ) in aqueous solution. The resin may take the form of microparticles or beads. The beads are prepared by cross-linking macromolecules such as hyperbranched PEI, and quaternizing the amines with hydrocarbon substituents.

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Номер записи: 31
23-03-2017 дата публикации

PPSA AND PSPA POLYMER-VIRUS COMPLEX AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME

Номер: US20170080036A1
Автор: DAYANANDA Kasala, Yun Chae Ok
Принадлежит:

The present invention relates to a complex of PPSA or PSPA polymer and a virus, and a pharmaceutical composition including the same. According to the present invention, when a polymer-virus complex formed using PPSA or PSPA polymer is used, transduction efficiency thereof to cells may be enhanced, an excellent therapeutic effect may thus be obtained when used as a pharmaceutical composition, and, therefore, the pharmaceutical agent may be useful as a therapeutic agent. 2. A polymer-virus complex in which the polymer represented by Formula 1 of is bound to a surface of a virus.3. The polymer-virus complex of claim 2 , wherein the virus is any one selected from the group consisting of adenovirus (Ad) claim 2 , adeno-associated virus (AAV) claim 2 , retrovirus claim 2 , lentivirus claim 2 , herpes simplex virus and vaccinia virus.4. The polymer-virus complex of claim 2 , wherein the virus is an Ad.5. A pharmaceutical composition claim 2 , comprising:{'claim-ref': {'@idref': 'CLM-00002', 'claim 2'}, '(a) a therapeutically effective amount of the polymer-virus complex of ; and'}(b) a pharmaceutically acceptable carrier.6. The pharmaceutical composition of claim 5 , wherein the composition further comprises a therapeutic gene.7. The pharmaceutical composition of claim 5 , wherein the virus is selected from the group consisting of adenovirus (Ad) claim 5 , adeno-associated virus (AAV) claim 5 , retrovirus claim 5 , lentivirus claim 5 , herpes simplex virus and vaccinia virus.8. The pharmaceutical composition of claim 5 , wherein the virus is an Ad.9. The pharmaceutical composition of claim 5 , wherein the composition is an anticancer composition.10. The pharmaceutical composition of claim 9 , wherein the cancer is breast cancer claim 9 , lung cancer claim 9 , stomach cancer claim 9 , liver cancer claim 9 , blood cancer claim 9 , bone cancer claim 9 , pancreatic cancer claim 9 , skin cancer claim 9 , head and neck cancer claim 9 , dermal or ocular melanoma claim 9 , sarcoma ...

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Номер записи: 32
12-06-2014 дата публикации

PREPARING CHLORIDE-FREE POLYETHYLENEIMINES

Номер: US20140163199A1
Автор: Dietsche Frank, HUEFFER Stephan, KRAMER Andreas
Принадлежит: BASF SE

In a method of preparing polyalkyleneimines from alkyleneimines in the presence of a liquid solvent, and a catalyst, the preparing is effected semi-discontinuously in one reaction container. The preparing is optionally effected in the presence of further additives. 1. A method of producing a polyalkyleneimine from an alkyleneimine , the method comprising:semi-discontinuously producing the polyalkyleneimine from the alkyleneimine in the presence of a liquid solvent and a catalyst in one reaction container.2. The method according to claim 1 ,wherein the semi-continuously producing is producing the polyalkyleneimine from the alkyleneimine in the presence of an additive.3. The method according to claim 1 ,wherein the semi-continuously producing is producing the polyalkyleneimine from the alkyleneimine without a chlorine-containing compound.4. The method according to claim 1 ,wherein the alkyleneimine is ethyleneimine, 2-methylaziridine, 1-(2-hydroxyethyl)aziridine, 1-(2-aminoethyl)aziridine, or a combination thereof.5. The method according to claim 1 ,wherein the liquid solvent is an aqueous solvent.6. The method according to claim 1 ,wherein the catalyst is an acid or an acidic compound.7. The method according to claim 2 ,wherein the additive is a primer or a comonomer.8. The method according to claim 7 ,wherein the primer is methylamine, dimethylamine, ethylamine, diethylamine, propylamine, ethylenediamine, diethylenetriamine, triethylenetetramine, or 3,3-dimethylaminopropylamine.9. A polyalkyleneimine obtained by the method according to .10. The polyalkyleneimine according to claim 9 ,wherein a molar mass distribution has a number average Mn of 300 to 500 000 g/mol and a polydispersity of 1.3 to 5.11. The polyalkyleneimine according to claim 9 ,wherein the polyalkyleneimine has a degree of branching of more than 50.12. The polyalkyleneimine according to claim 9 , comprising only a low proportion of chlorine-containing impurities of not more than 0.5 wt % based on an ...

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Номер записи: 33
12-03-2020 дата публикации

BINDERS

Номер: US20200079907A1
Автор: Pacorel Benedicte
Принадлежит:

The present invention relates to binder compositions with improved amine components, and a method of manufacturing a collection of matter bound by said binder compositions. 1. A binder composition comprising a polymeric product of at least one carbohydrate component and at least one amine component , wherein the at least one amine component comprises a substituted or unsubstituted primary diamine and/or a substituted or unsubstituted primary triamine.2. The binder composition according to claim 1 , wherein the polymeric product is a product of the at least one carbohydrate component claim 1 , the at least one amine component claim 1 , and at least one additional crosslinker which is different from the amine component.3. The binder composition according to claim 1 , wherein the substituted or unsubstituted primary diamine is a compound wherein the amino groups are separated in the molecule by a spacer group having a length of 4 to 12 atoms.4. The binder composition according to claim 3 , wherein the substituted or unsubstituted primary diamine is a compound wherein the amino groups are separated in the molecule by a spacer group having a length of 6 to 8 atoms.5. The binder composition according to claim 3 , wherein the primary diamine further contains at least one substituent within the spacer group.6. The binder composition according to claim 1 , wherein the substituted or unsubstituted primary triamine is a compound wherein at least two of the primary amino groups are separated in the molecule by a spacer group having a length of 4 to 12 atoms.7. The binder composition according to claim 6 , wherein the substituted or unsubstituted primary triamine is a compound wherein at least two of the primary amino groups are separated in the molecule by a spacer group having a length of 6 to 8 atoms.8. The binder composition according to claim 1 , wherein the at least one carbohydrate component is selected from the group consisting of monosaccharides claim 1 , disaccharides ...

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Номер записи: 34
25-03-2021 дата публикации

BINDERS

Номер: US20210087339A1
Автор: Pacorel Benedicte
Принадлежит:

The present invention relates to binder compositions with improved amine components, and a method of manufacturing a collection of matter bound by said binder compositions. 1. A binder composition comprising a polymeric product of at least one carbohydrate component and at least one amine component , wherein the at least one amine component comprises a substituted or unsubstituted primary diamine and/or a substituted or unsubstituted primary triamine.2. The binder composition according to claim 1 , wherein the polymeric product is a product of the at least one carbohydrate component claim 1 , the at least one amine component claim 1 , and at least one additional crosslinker which is different from the amine component.3. The binder composition according to claim 1 , wherein the substituted or unsubstituted primary diamine is a compound wherein the amino groups are separated in the molecule by a spacer group having a length of 4 to 12 atoms.4. The binder composition according to claim 3 , wherein the substituted or unsubstituted primary diamine is a compound wherein the amino groups are separated in the molecule by a spacer group having a length of 6 to 8 atoms.5. The binder composition according to claim 3 , wherein the primary diamine further contains at least one substituent within the spacer group.6. The binder composition according to claim 1 , wherein the substituted or unsubstituted primary triamine is a compound wherein at least two of the primary amino groups are separated in the molecule by a spacer group having a length of 4 to 12 atoms.7. The binder composition according to claim 6 , wherein the substituted or unsubstituted primary triamine is a compound wherein at least two of the primary amino groups are separated in the molecule by a spacer group having a length of 6 to 8 atoms.8. The binder composition according to claim 1 , wherein the at least one carbohydrate component is selected from the group consisting of monosaccharides claim 1 , disaccharides ...

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Номер записи: 35
29-03-2018 дата публикации

Carbon material-polymer strain sensitive film and its preparation method

Номер: US20180086893A1
Автор: Du Xiaosong, GUO Rui, Jiang Yadong, LI Weizhi, TAI Huiling, Ye Xueliang, Yuan Zhen
Принадлежит:

A carbon material-polymer strain sensitive film and its preparation method are disclosed. The carbon material-polymer strain sensitive film includes multiple layers of carbon sensitive films and multiple layers of polymer films, wherein the multiple layers of carbon sensitive films and the multiple layers of polymer films form a multi-layer composite film in sequence through a layer-by-layer assembly process. The preparation method includes steps of: cleaning, processing a hydrophilic treatment and processing a hydrophobic treatment on a rigid substrate in sequence; preparing a carbon material in dispersion solution and a polymer dispersion solution; through a layer-by-layer self-assembly process, growing the polymer and the carbon material in a form of layer-by-layer on the rigid substrate; transferring the composite film from the rigid substrate to a flexible substrate; and pasting two electrodes at two ends of the composite film and encapsulating with a flexible film. 1. A carbon material-polymer strain sensitive film comprising: multiple layers of carbon sensitive films and multiple layers of polymer films , wherein the multiple layers of carbon sensitive films and the multiple layers of polymer films form a multi-layer composite film in sequence through a layer-by-layer assembly process.2. The carbon material-polymer strain sensitive film claim 1 , as recited in claim 1 , wherein: the carbon sensitive films are made from a material which is at least one member selected from a group consisting of graphene claim 1 , graphene oxide claim 1 , reduced graphene oxide claim 1 , graphene quantum dot claim 1 , graphene nanometer sheet claim 1 , carbon nanotube claim 1 , carbon nanofiber claim 1 , nanometer porous carbon and nano graphite.3. The carbon material-polymer strain sensitive film claim 1 , as recited in claim 1 , wherein: the polymer films are made from a material which is soluble in water or alcohol and has a sticky property.4. The carbon material-polymer ...

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Номер записи: 36
21-03-2019 дата публикации

BINDERS

Номер: US20190085128A1
Автор: Pacorel Benedicte
Принадлежит:

The present invention relates to binder compositions with improved amine components, and a method of manufacturing a collection of matter bound by said binder compositions. 1. A binder composition comprising a polymeric product of at least one carbohydrate component and at least one amine component , wherein the at least one amine component comprises a substituted or unsubstituted primary diamine and/or a substituted or unsubstituted primary triamine.2. The binder composition according to claim 1 , wherein the polymeric product is a product of the at least one carbohydrate component claim 1 , the at least one amine component claim 1 , and at least one additional crosslinker which is different from the amine component.3. The binder composition according to claim 1 , wherein the substituted or unsubstituted primary diamine is a compound wherein the amino groups are separated in the molecule by a spacer group having a length of 4 to 12 atoms.4. The binder composition according to claim 3 , wherein the substituted or unsubstituted primary diamine is a compound wherein the amino groups are separated in the molecule by a spacer group having a length of 6 to 8 atoms.5. The binder composition according to claim 3 , wherein the primary diamine further contains at least one substituent within the spacer group.6. The binder composition according to claim 1 , wherein the substituted or unsubstituted primary triamine is a compound wherein at least two of the primary amino groups are separated in the molecule by a spacer group having a length of 4 to 12 atoms.7. The binder composition according to claim 6 , wherein the substituted or unsubstituted primary triamine is a compound wherein at least two of the primary amino groups are separated in the molecule by a spacer group having a length of 6 to 8 atoms.8. The binder composition according to claim 1 , wherein the at least one carbohydrate component is selected from the group consisting of monosaccharides claim 1 , disaccharides ...

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Номер записи: 37
07-04-2016 дата публикации

N-PHOSPHONOMETHYLGLYCINE GUANIDINE DERIVATIVE SALTS

Номер: US20160095317A1
Автор: Brinker Ronald J., Lemercier Alain, SOULA Olivier
Принадлежит:

The present invention provides guanidine compounds and salts thereof that may be useful, for example, in the preparation of herbicidal compositions. The compounds may be used, for example, to prepare N-phosphonomethylglycine guanidine salts having improved herbicidal efficacy over glyphosate alone. 2. The compound of wherein R claim 1 , R claim 1 , Rand Rare independently hydrogen or C-Calkyl.3. The compound of wherein Ris 3 claim 1 ,6 claim 1 ,9 claim 1 ,12 claim 1 ,15 claim 1 ,18-hexaazatriacontyl or (2 claim 1 ,3-diamino)tallow and R claim 1 , R claim 1 , Rand Rare hydrogen.4. The compound of wherein Ris 3 claim 1 ,6 claim 1 ,9 claim 1 ,12 claim 1 ,15 claim 1 ,18-hexaazatriacontyl or (2 claim 1 ,3-diamino)tallow and R claim 1 , R claim 1 , Rand Rare methyl.5. The compound of wherein Ris polyethyleneimino and R claim 1 , R claim 1 , Rand Rare hydrogen.6. The compound of wherein Ris polyethyleneimino and R claim 1 , R claim 1 , R claim 1 , and Rare methyl.7. An aqueous herbicidal composition comprising the compound of and an herbicide component comprising one or more herbicides.8. The composition of wherein the herbicide component comprises glyphosate.9. The composition of wherein the herbicide component comprises one or more water-soluble herbicides selected from the group consisting of acifluorfen claim 7 , acrolein claim 7 , amitrole claim 7 , asulam claim 7 , benazolin claim 7 , bentazon claim 7 , bialaphos claim 7 , bromacil claim 7 , bromoxynil claim 7 , chloramben claim 7 , chloroacetic acid claim 7 , clopyralid claim 7 , 2 claim 7 ,4-D claim 7 , 2 claim 7 ,4-DB claim 7 , dalapon claim 7 , dicamba claim 7 , dichlorprop claim 7 , difenzoquat claim 7 , diquat claim 7 , endothall claim 7 , fenac claim 7 , fenoxaprop claim 7 , flamprop claim 7 , flumiclorac claim 7 , fluoroglycofen claim 7 , flupropanate claim 7 , fomesafen claim 7 , fosamine claim 7 , glufosinate claim 7 , imazameth claim 7 , imazamethabenz claim 7 , imazamox claim 7 , imazapic claim 7 , ...

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Номер записи: 38
09-04-2015 дата публикации

Compositions comprising polyamine polymer compatible perfume materials

Номер: US20150098922A1
Автор: Cahit Eylem, Judith Ann Hollingshead, Prakash J. Madhav, Steven Anthony Horenziak, Zaiyou Liu
Принадлежит: Procter and Gamble Co

Compositions comprising polyamine polymers and polyamine polymer compatible perfume materials, more specifically, perfume aldehydes that do not react with polyamine polymers are provided.

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Номер записи: 39
30-03-2017 дата публикации

N-TYPE ORGANIC SEMICONDUCTOR FORMULATIONS AND DEVICES

Номер: US20170092865A1
Автор: Sun Bin, Yuning LI
Принадлежит:

The present invention discloses an organic semiconductor formulation comprising an organic semiconductor (OSC) and an organic nitrogen-containing additive (ONA) capable of enhancing the n-type performance of the organic semiconductor. The semiconductor formulation disclosed herein is suitable for producing n-type semiconductor thin films for use in a variety of electronic applications and devices. 1. An organic semiconductor formulation comprising:an organic semiconductor (OSC); andan organic nitrogen-containing additive (ONA) capable of enhancing n-type performance of the organic semiconductor.2. The formulation according to claim 1 , wherein the ONA is a linear polyethylenimine claim 1 , branched polyethylenimine claim 1 , at least partially ethoxylated polyethylenimine claim 1 , a modified polyethylenimine claim 1 , or a copolymer of polyethylenimine with a second polymer.4. The formulation according to claim 3 , wherein R3 is aryl claim 3 , substituted aryl claim 3 , heteroaryl or substituted heteroaryl.8. The formulation according to claim 1 , wherein the ONA is an amino acid having a positively charged side chain at pH 7.4.12. The organic semiconductor formulation of wherein the where the organic semiconductor has a LUMO energy level of −3 eV or lower.14. A method of enhancing n-type performance of an organic semiconductor claim 1 , comprising mixing the OSC with an organic nitrogen-containing additive (ONA) capable of enhancing the n-type performance of the organic semiconductor to thereby form an n-type semiconductor formulation claim 1 , whereby the n-type performance of the organic semiconductor is enhanced.15. An electronic device claim 1 , comprising a semiconductor layer comprising:an organic semiconductor; andan organic nitrogen-containing additive (ONA) capable of enhancing the n-type performance of the organic semiconductor.16. The electronic device of claim 1 , wherein the semiconductor layer comprises an organic semiconductor formulation as defined ...

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Номер записи: 40
06-04-2017 дата публикации

ANTIMICROBIAL POLYMERS FORMED BY BULK POLYADDITION

Номер: US20170094964A1
Автор: Chan Julian M. W., Hedrick James L., Ono Robert J., Teo Jye Yng, Yang Yi Yan, ZHANG Mu San
Принадлежит:

Cationic antimicrobial polymers have been synthesized by a bulk addition polymerization of a nucleophilic agent comprising two tertiary amines and an electrophilic agent that comprises two leaving groups and an aromatic ring between the leaving groups. The reaction solvent for the polymerization is chosen to allow precipitation of the cationic polymer at the polymerization temperature, thereby limiting molecular weight. Quaternization and polymerization occur concurrently. The cationic polymers can be highly active against Gram-negative and Gram-positive microbes, and/or fungi. The cationic polymers can also be non-hemolytic and non-cytotoxic at the effective concentration against the microbes. 2. The cationic polymer of claim 1 , wherein the cationic polymer is a homopolymer.3. The cationic polymer of claim 1 , wherein each R′ is methyl.4. The cationic polymer of claim 1 , wherein each X′ is chloride.5Staphylococcus aureusS. aureusEscherichia coliE. coliCandida albicansC. albicansPseudomonas aeruginosaP. aeruginosaStaphylococcus epidermidisS. epidermidisStaphylococcus aureusEnterococcusAcinetobacter baumanniiA. baumanniiKlebsiella pneumoniaeK. pneumoniaeCryptococcus neoformansC. neoformans. The cationic polymer of claim 1 , wherein the cationic polymer is an effective antimicrobial agent capable of killing a microbe selected from the group consisting of () claim 1 , () claim 1 , () claim 1 , () claim 1 , () claim 1 , Methicillin-resistant (MRSA) claim 1 , Vancomycin-resistant (VRE) claim 1 , () claim 1 , () claim 1 , () claim 1 , and yeasts.7. The cationic polymer of claim 6 , wherein the cationic polymer comprises the cationic repeat units of formulas (C-5) and (C-7) in a (C-5):(C-7) molar ratio of 90:10 to 50:50.8. A method of killing a microbe claim 1 , comprising contacting the microbe with the cationic polymer of .9. An antimicrobial composition claim 1 , comprising the cationic polymer of and a second component bound together by non-covalent interactions.10. ...

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Номер записи: 41
28-03-2019 дата публикации

POLYALKYLENE IMINE BASED POLYMERS HAVING POLYESTER GROUPS

Номер: US20190092903A1
Автор: Auschra Clemens, Kou Huiguang, MAIER Matthias, Onclin Steffen
Принадлежит: BASF SE

The present invention relates to polyalkylene imine based polymers, which have aliphatic polyester groups attached to the polyalkylenimine backbone via an carboxamide group. The novel polymers are particularly useful as dispersants for pigments, in particular as dispersants for pigments in non-aqueous compositions. The polyalkylene imine based polymers are characterized by having a) a polyalkylene imine backbone; b) at least one aromatic moiety P.1, which is bound to a nitrogen atom of the polyalkylene imine backbone via an carboxamide or carboximide group; and c) at least one aliphatic polyester moiety P.2, which is bound to a nitrogen atom of the polyalkylene imine backbone via an carboxamide group. 1: A polymer havinga) a polyalkyleneimine backbone;b) at least one aromatic moiety P.1, which is bound to a nitrogen atom of the polyalkyleneimine backbone via a carboxamide or carboximide group; andc) at least one aliphatic polyester moiety P.2, which is bound to a nitrogen atom of the polyalkyleneimine backbone via a carboxamide group.5: The polymer of claim 4 , wherein:A is 1,4-butandiyl or 1,5-pentandiyl or a combination thereof, and{'sup': 'x', 'sub': 6', '20', '6', '20', '6', '20', '6', '20, 'Ris hydrogen, C(═O)—C-C-alkyl or C(═O)—C-C-alkenyl, wherein C-C-alkyl and C-C-alkenyl are unsubstituted or carry 1 or 2 OH groups.'}6: The polymer of claim 1 , wherein the poly(alkylenimine) is a poly(ethylenimine).7: The polymer of claim 1 , comprisinga) from 1 to 25% by weight, based on the total weight of the polymer, of the polyalkyleneimine backbone;b) from 1 to 25% by weight, based on the total weight of the polymer, of the at least one aromatic moiety P.1; andc) from 50 to 98% by weight, based on the total weight of the polymer, of the at least one aliphatic polyester moiety P.2.8: The polymer of claim 1 , wherein the poly(alkylenimine) further has protonated or quaternized amino groups.9: A process for making the polymer according to claim 1 , comprising:i) reacting ...

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Номер записи: 42
12-04-2018 дата публикации

Polysaccharide-Polyamine Copolymers For Removal Of Phosphate

Номер: US20180099007A1
Автор: Mitchell James W., Yang Dazhi
Принадлежит: HOWARD UNIVERSITY

Covalently cross-linked copolymers are described herein. More specifically, polysaccharide-polyamine copolymeric matrices or structures and cationic copolymeric matrices are described herein. The polysaccharide-polyamine copolymers, when protonated, can form cationic copolymeric matrices having exceptionally high densities of cationic sites. In one form, the covalently cross-linked copolymers provide a three-dimensional structure, especially when hydrated. 1. A polysaccharide-polyamine copolymer having an amino functionality which will provide a protonatable copolymeric material having a three-dimensional structure with cationic sites through protonation , the polysaccharide-polyamine copolymer comprising:a selectively oxidized polysaccharide having a 2,3-dialdehyde moiety; andamino polymers which provide an amino functionality, the amino polymers cross linking the oxidized polysaccharides to provide a particulate polysaccharide-polyamine copolymer having an amino functionality which when protonated will provide the cationic copolymeric material with a nitrogen content of at least 12.3 wt. %, both the polysaccharide-polyamine copolymer and cationic copolymeric material being water insoluble.2. The polysaccharide-polyamine copolymer of claim 1 , wherein the amino polymers have a nitrogen content of at least 24.5 wt. % claim 1 , based on the weight of the amino polymers and a molecular weight in the range of from about 15 claim 1 ,000 to about 900 claim 1 ,000.3. The polysaccharide-polyamine copolymer of claim 1 , wherein the selectively oxidized polysaccharide are selected from the group consisting of selectively oxidized cellulose claim 1 , selectively oxidized starch claim 1 , selectively oxidized amylose claim 1 , selectively oxidized chitosan claim 1 , selectively oxidized dextran claim 1 , selectively oxidized glycogen claim 1 , selectively oxidized chitin and mixtures thereof claim 1 , the polysaccharide having been oxidized in an amount effective to provide ...

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Номер записи: 43
12-04-2018 дата публикации

BINDER

Номер: US20180100034A1
Автор: Pacorel Benedicte
Принадлежит:

The present invention relates to binder compositions with an improved amine component, and a method of manufacturing a collection of matter bound by said binder compositions. 1. A binder composition comprising a polymeric product of at least one carbohydrate component and at least one amine component , wherein the at least one amine component comprises a polyethyleneimine.2. The binder composition according to claim 1 , wherein the polyethyleneimine is a branched polyethyleneimine.3. The binder composition according to claim 1 , wherein the polyethyleneimine has an average molecular weight in the range of 500 to 1.000.000 g/mol.4. The binder composition according to claim 1 , wherein the polyethyleneimine has a ratio of primary amino groups to secondary+tertiary amino groups in the range of 1:2 to 1:1.5. The binder composition according to claim 1 , wherein the polyethyleneimine has a ratio of primary amino groups to secondary amino groups to tertiary amino groups in the range of 1:1.1:0.7 to 1:0.9:0.5.6. The binder composition according to claim 1 , wherein the polyethyleneimine has a viscosity in water at a concentration of 50 wt.-% (25° C.) of 100 to 50.000 mPa·s.7. The binder composition according to claim 1 , wherein the at least one carbohydrate component is selected from the group consisting of monosaccharides claim 1 , disaccharides claim 1 , polysaccharides or a reaction product thereof.8. The binder composition according to claim 1 , wherein the at least one carbohydrate component is selected from the group consisting of ribose claim 1 , arabinose claim 1 , xylose claim 1 , lyxose claim 1 , glucose (dextrose) claim 1 , mannose claim 1 , galactose claim 1 , allose claim 1 , altrose claim 1 , talose claim 1 , gulose claim 1 , idose claim 1 , fructose claim 1 , psicose claim 1 , sorbose claim 1 , dihydroxyacetone claim 1 , sucrose and tagatose claim 1 , as well as mixtures thereof.9. The binder composition according to claim 1 , wherein the weight ratio ...

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Номер записи: 44
12-04-2018 дата публикации

Stable immobilized amine sorbents for ree and heavy metal recovery from liquid sources

Номер: US20180100065A1
Автор: Brian W. Kail, McMahan L. Gray, Qiuming WANG, Walter C. Wilfong
Принадлежит: US Department of Energy

Materials, methods of making, and methods of using a stable and regenerable immobilized amine sorbents for rare earth element and heavy metal recovery from liquid sources. Embodiments of the invention relate to the novel combination of different polyamines, primarily polyethylenimine Mw=800 (PEI 800 ), and an epoxysilane, namely 2-(3,4-epoxycyclohexyl)ethyltrimethoxysilane (ECTMS), covalently immobilizing the REE and heavy metal-adsorbing amine sites within low cost, porous silica particles.

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Номер записи: 45
12-04-2018 дата публикации

PROCESS FOR INHIBITING THE CORROSION OF METAL SURFACES

Номер: US20180100239A1
Автор: ODIOT Karine
Принадлежит: BASF SE

Process for inhibiting the corrosion of a metal surface M, wherein said metal surface M is essentially made of carbon steel, comprising treating said metal surface M with a polyethylene imine P in aqueous medium. 1. A process for inhibiting corrosion of a metal surface M made of carbon steel , the process comprising treating the metal surface M with a polyethylene imine in an aqueous medium.2. The process of claim 1 , wherein the aqueous medium has a pH of 6.0 to 9.0.3. The process of claim 1 , wherein the metal surface M is part of a cooling or heating circuit.4. The process of claim 1 , wherein the metal surface M is part of an open claim 1 , an open recirculating claim 1 , or a closed cooling circuit.5. The process of claim 1 , wherein the polyethylene imine has an average molar mass Mn of 500 to 25 claim 1 ,000 g/mol.6. The process of claim 1 , wherein the polyethylene imine has a Brookfield viscosity of 100 to 15000 mPas in 50% by weight solution in water.7. The process of claim 1 , wherein the polyethylene imine is present in the aqueous medium in an amount 1 to 1000 ppm by weight.8. The process of claim 1 , wherein the aqueous medium is treated with the polyethylene imine in the absence of a poly(meth)acrylic acid or salts thereof.9. A corrosion inhibitor claim 1 , comprising a polyethylene imine claim 1 , wherein the corrosion inhibitor is adapted to function as a corrosion inhibitor in cooling circuits made of carbon steel. The present invention is related to a process for inhibiting the corrosion of a metal surface M, wherein said metal surface M is essentially made of carbon steel, comprising treating said metal surface M with a polyethylene imine P in aqueous medium.The corrosion of metal is an almost omnipresent phenomenon for all surfaces that are in contact with water.Among the surfaces where the inhibition of corrosion is of particular importance are circuits like cooling or heating circuits that are in permanent contact with water.Numerous ...

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Номер записи: 46
08-04-2021 дата публикации

QUATERNARY CATIONIC POLYMERS

Номер: US20210102044A1
Автор: Cramm Jeffrey R., Dhawan Ashish, Huang Xiaodong, Moloney Jeremy, Xiong Kun, Zong Zhengang
Принадлежит: ECOLAB USA, Inc.

A cationic polymer salt composition is provided that includes a reaction product derived from reaction of a polyamine or a polyalkyleneimine and a substituted alkyl trialkyl quaternary ammonium salt. Also provided are surfactant compositions. The compositions may also include carriers, such as water, methanol, ethanol, propanol, isopropanol, butanol, isobutanol, monoethyleneglycol, an ethyleneglycol monobutyl ether, and hexylene glycol. 3. The method of claim 2 , wherein the surface is part of a wellbore or equipment used in the production claim 2 , transportation claim 2 , storage claim 2 , and/or separation of the fluid.4. The method of claim 2 , wherein the surface is part of equipment used in a coal-fired process claim 2 , a waste-water process claim 2 , a farm claim 2 , a slaughter house claim 2 , a land-fill claim 2 , a municipality waste-water plant claim 2 , a coking coal process claim 2 , or a biofuel process.5. The method of claim 3 , wherein the equipment comprises a pipeline claim 3 , a storage vessel claim 3 , downhole injection tubing claim 3 , a flow line claim 3 , or an injection line.6. The method of claim 2 , wherein the fluid comprises natural gas or a liquid hydrocarbon.7. The method of claim 6 , wherein the liquid hydrocarbon comprises crude oil claim 6 , heavy oil claim 6 , processed residual oil claim 6 , bituminous oil claim 6 , cocker oil claim 6 , gas oil claim 6 , fluid catalytic cracker feed or slurry claim 6 , naphtha claim 6 , diesel fuel claim 6 , fuel oil claim 6 , jet fuel claim 6 , gasoline claim 6 , or kerosene.11. The method of claim 8 , wherein the composition is added to the process water used in an industrial process selected from the group consisting of cooling water system claim 8 , boiler water system claim 8 , petroleum wells claim 8 , downhole formations claim 8 , geothermal wells claim 8 , mineral washing claim 8 , flotation and benefaction claim 8 , papermaking claim 8 , gas scrubbers claim 8 , air washers claim 8 , ...

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Номер записи: 47
02-04-2020 дата публикации

Ligand functionalized polymers

Номер: US20200102345A1
Автор: Catherine A. Bothof, Erin A. Satterwhite, George W. Griesgraber, James I. Hembre, Jerald K. Rasmussen, Kannan Seshadri, Louis C. Haddad, Robert T. Fitzimons, JR., Yi He
Принадлежит: 3M Innovative Properties Co

Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.

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Номер записи: 48
17-07-2014 дата публикации

Antimicrobial crosslinked polymers containing biomass derived materials

Номер: US20140200314A1
Автор: Garret D. Figuly, Henry Keith Chenault, Mark Allen Andrews
Принадлежит: EI Du Pont de Nemours and Co

Novel, crosslinked polymers using biomass derived materials, such as aldaric acids and derivatives, are provided. The polymers can be used as hydrogels and in antimicrobial compositions.

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Номер записи: 49
25-08-2022 дата публикации

Substituted phenyl boronic acid containing polymers and methods of use

Номер: US20220265703A1
Автор: Ashish Nimgaonkar, Steven C. Polomoscanik, Thomas Henry Jozefiak
Принадлежит: Glyscend Inc

The disclosure relates to cationic polymers functionalized with substituted phenylboronic acid groups and to methods of using the same to treat metabolic and gastrointestinal disorders.

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Номер записи: 50
25-08-2022 дата публикации

POUR POINT DEPRESSANT

Номер: US20220267523A1
Автор: BÖMER Jörg, Giebelhaus Irina, Heitzer Jennifer, Lorenz Markus, Okkel Andreas, Scranton Stacy, Stannek Peter Walter, Von Haaren Jan
Принадлежит:

The invention relates to a polymer or oligomer comprising a) An oligomeric or polymeric core comprising carbon atoms and at least one of oxygen atoms and nitrogen atoms, and b) at least three hydrocarbyl terminal and/or pending groups having 12 to 100 carbon atoms, wherein the hydrocarbyl groups are linked to the core via c) a linking moiety comprising i) a urethane group and ii) a group selected from urethane group, urea group, and biuret group. 1. A polymer or oligomer comprisinga) an oligomeric or polymeric core comprising carbon atoms and at least one of oxygen atoms and nitrogen atoms, andb) at least three hydrocarbyl terminal and/or pending groups having 12 to 100 carbon atoms, wherein the hydrocarbyl groups are linked to the core viac) a linking moiety comprising i) a urethane group and ii) from one or more of a urethane group, a urea group, and a biuret group.2. The polymer or oligomer according to claim 1 , wherein the hydrocarbyl groups are linear or branched aliphatic groups.3. The polymer or oligomer according to claim 1 , wherein the polymer or oligomer comprises 3 to 600 hydrocarbyl groups b).4. The polymer or oligomer according to claim 1 , wherein the linking moiety comprises an aromatic group located between the urethane group and the group selected from urethane group claim 1 , urea group and biuret group.5. The polymer or oligomer according to claim 1 , wherein the core is selected from a polymer or oligomer of ethyleneimine claim 1 , a polymer or oligomer of a trialkanol amine claim 1 , a branched polyester claim 1 , and a polyamide.6. The polymer of oligomer according to claim 1 , wherein the polymer or oligomer comprises amine groups neutralized by a carboxylic acid having 6 to 24 carbon atoms.7. (canceled)8. A method of decreasing the amount of solid precipitate in a hydrocarbon based fluid upon temperature decrease claim 1 , comprising adding to the hydrocarbon based fluid a polymer or oligomer according to .9. A composition comprising{'claim ...

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Номер записи: 51
25-08-2022 дата публикации

Mixtures Containing an Aminically Crosslinkable Rubber and Polyethyleneimine

Номер: US20220267524A1
Автор: Meenenga Vincenza, OPRISONI Cristian
Принадлежит: LANXESS DEUTSCHLAND GMBH

The invention relates to mixtures containing at least one aminically crosslinkable rubber and a cross-linking system, which consists of at least one crosslinker and optionally at least one vulcanization accelerator, the at least one crosslinker containing polyethylene imine. The invention further relates to the production and to the use of said mixtures; and to the vulcanized products that can be obtained from the mixture, in particular in the form of rubber articles, in particular seals, hoses, membranes and o-rings. 1. A mixture comprisingat least one aminically crosslinkable rubber anda crosslinking system consisting of at least one crosslinker and optionally at least one vulcanization accelerator, wherein the at least one crosslinker comprises polyethyleneimine and wherein the total content of the vulcanization accelerators diphenylguanidine (DPG), di-ortho-tolyl-guanidine (DOTG) and 1-(ortho-tolyl)biguande of the crosslinking system in the mixture is not more than 0.4 phr.2. The mixture as claimed in claim 1 , wherein the crosslinking system consists to an extent of ≥80% by weight claim 1 , based on the total mass of the crosslinking system claim 1 , of at least one crosslinker claim 1 , wherein the at least one crosslinker comprises polyethyleneimine.3. The mixture as claimed in claim 1 , wherein the at least one crosslinker comprises polyethyleneimine and at least one diamine.4. The mixture as claimed in claim 1 , wherein the at least one crosslinker consists of polyethyleneimine and at least one diamine.5. The mixture as claimed in claim 1 , wherein the at least one crosslinker consists of polyethyleneimine.6. The mixture as claimed in claim 1 , wherein the content of polyethyleneimine is from 0.001 to 20 phr.7. The mixture as claimed in claim 3 , wherein the content of the at least one diamine claim 3 , is from 0.01 bis 5 phr.8. The mixture as claimed in claim 1 , wherein the at least one aminically crosslinkable rubber is a carboxyl-containing rubber.9. ...

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Номер записи: 52
25-08-2022 дата публикации

BIODEGRADABLE CATIONIC POLYMERS AND USES THEREOF

Номер: US20220267525A1
Автор: BOCKUVIENE Alma, MAKUSKA Ricardas, VAREIKIS Ausvydas, Zaliauskiene Lolita, ZIGMANTAS Sarunas
Принадлежит:

Disclosed herein are poly(hydroxylalkyleneimine disulfide)polymers, which have both desirable transfection properties and reduced toxicity. 115-. (canceled)19. The cationic polymer of claim 16 , wherein at least one of Rand Ris a substituted or unsubstituted heteroalkyl.20. The cationic polymer of claim 16 , resulting from the polymerization of(a) 1,3-dibromo-2-propanol (DBP);(b) cystamine (CT), and optionally;(c) 1,3-diamino-2-propanol (DAP).21. The cationic polymer of claim 20 , wherein the ratio of DBP:CT:DAP is about: 1:1:0; 1:0.9:0.1; 1:0.8:0.2; 1:0.75:0.25; 1:0.7:0.3; 1:0.6:0.4; 1:0.5:0.5; 1:0.4:0.6; 1:0.3:0.7; 1:0.25:0.75; 1:0.2:0.8; or 1:0.1:0.9.22. The cationic polymer of claim 21 , wherein the ratio of DBP:CT:DAP is about 1:1:0; 1:0.7:0.3 or 1:0.5:0.5.23. The cationic polymer of claim 16 , wherein the weight average molecular weight (M) is about 4 claim 16 ,000; 5 claim 16 ,000; 6 claim 16 ,000; 7 claim 16 ,000; 8 claim 16 ,000; 9 claim 16 ,000; 10 claim 16 ,000; 12 claim 16 ,000; 14 claim 16 ,000; 16 claim 16 ,000; 18 claim 16 ,000; or 20 claim 16 ,000;24. The cationic polymer of claim 23 , wherein the weight average molecular weight (M) is about 4 claim 23 ,000; 5 claim 23 ,000; 6 claim 23 ,000; 7 claim 23 ,000; 8 claim 23 ,000; 9 claim 23 ,000 or 10 claim 23 ,000;25. A composition comprising(a) a cationic polymer that is a poly(hydroxylalkyleneimine disulfide); and(b) at least one nucleic acid.26. The composition of claim 23 , wherein the cationic polymer is that of .27. The composition of claim 25 , further comprising one or more adjuvants.28. The composition of claim 25 , wherein said at least one nucleic acid is a DNA or a RNA.29. The composition of claim 28 , wherein said RNA is an siRNA.30. A method of delivering at least one nucleic acid to a cell comprising contacting a cell with the composition of .31. The method of claim 30 , wherein said method is carried out in vivo.32. The method of claim 30 , wherein said method is carried out in vitro.33. ...

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Номер записи: 53
25-04-2019 дата публикации

THERMOPLASTIC ELASTOMER COMPOSITION AND METHOD FOR PRODUCING THE SAME

Номер: US20190119471A1
Автор: Chino Keisuke, SUZUKI Hiroaki
Принадлежит: JXTG NIPPON OIL & ENERGY CORPORATION

A thermoplastic elastomer composition including at least one elastomer component selected from the group consisting of elastomeric polymers (A) each of which has a side chain (a) containing a hydrogen-bond cross-linkable moiety having a carbonyl-containing group and/or a nitrogen-containing heterocycle and has a glass-transition point of 25° C. or below, and elastomeric polymers (B) each of which contains a hydrogen-bond cross-linkable moiety and a covalent-bond cross-linking moiety in a side chain and has a glass-transition point of 25° C. or below, wherein the elastomer component is at least one reaction product selected from the group consisting of specific reaction products (I) to (VI), and the composition further comprises an organically modified clay, a content ratio of which is 20 parts by mass or less relative to 100 parts by mass of the elastomer component. 1. A thermoplastic elastomer composition comprising at least one elastomer component selected from the group consisting of elastomeric polymers (A) each of which has a side chain (a) containing a hydrogen-bond cross-linkable moiety having a carbonyl-containing group and/or a nitrogen-containing heterocycle and has a glass-transition point of 25° C. or below , and elastomeric polymers (B) each of which contains a hydrogen-bond cross-linkable moiety and a covalent-bond cross-linking moiety in a side chain and has a glass-transition point of 25° C. or below , whereinthe elastomer component is at least one reaction product selected from the group consisting of the following reaction products (I) to (VI):a reaction product (I) of a maleic anhydride-modified elastomeric polymer with at least one compound among hydrocarbon compounds each having two or more substituents of at least one type selected from hydroxy groups, thiol groups, and amino groups;a reaction product (II) of a hydroxy group-containing elastomeric polymer with a compound having two or more substituents of at least one type selected from carboxy ...

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Номер записи: 54
02-05-2019 дата публикации

COMPOSITIONS AND METHODS FOR THE PROPHYLAXIS AGAINST AND THE TREATMENT OF THE ADHESION PROCESS

Номер: US20190125886A1
Автор: Shurygin Mikhail Gennadievich, Shurygina Irina Aleksandrovna
Принадлежит:

The invention relates to inhibitory compounds of a p38 MAP kinase having a structure of type (I)-(VII) which can be used for the treatment or prophylaxis of adhesion. Pharmaceutical compositions are disclosed containing an effective amount of the substance SB203580 or one or more of the conjugated compounds of type (I)-(VII) or a combination thereof, and a pharmaceutically acceptable carrier, a diluent or an excipient. Also disclosed is the use of the substance SB203580 as an agent having anti-adhesion activity. Also disclosed is a method for the prophylaxis and/or treatment of a disease or a condition in which there is a possibility of the formation and/or growth of adhesions, which makes it possible to dispense with the additional administration of a preparation in the post-operative period. 2. The method of claim 1 , wherein the inhibitory molecule is 4-(4-fluorinephenyl)-2-(4-methylsulphinylphenyl)-5-(4-pyridyl)-1H-imidazole.3. The method of claim 1 , wherein the basic claim 1 , water-solvable polymer is of natural or synthetic origin.4. The method of claim 3 , wherein the basic claim 3 , water-solvable polymer is polyethylenimine claim 3 , a copolymer of polyethylenimine claim 3 , polyvinylpyridine claim 3 , a copolymer of polyvinylpyridine claim 3 , polyvinylimidazole claim 3 , a copolymer of polyvinylimidazole claim 3 , polyvinyltriazole claim 3 , a copolymer of polyvinyltriazole claim 3 , chitosan claim 3 , a derivative of chitosan claim 3 , carboxymethyl cellulose salts claim 3 , polyacrylic acid claim 3 , a copolymer of polyacrylic acid claim 3 , polymethacrylic acid claim 3 , a copolymer of polymethacrylic acid claim 3 , polymethylmethacrylic claim 3 , or a copolymer of polymethylmethacrylic.5. The method of claim 1 , wherein the basic claim 1 , water-solvable polymer is chitosan.7. The method of claim 6 , wherein the patient has undergone surgery or procedure with invasion into serous cavity.8. The method of claim 6 , wherein the patient is due to ...

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Номер записи: 55
11-05-2017 дата публикации

IMPROVED POPPET FOR CRYOGENIC FLUID COUPLING

Номер: US20170129970A1
Автор: Demin Mikhail, Henfling Richard N.
Принадлежит: JC CARTER LLC

Subject polymers have a plurality of repeating units having amino-bis-phosphonate functionality pendent groups of a polyacrylate, polymethacrylate, polyacrylamide, polymethacrylamide, or linear polyethyleneimine. The polymers are prepared from a plurality of monomers comprising amino-te-phosphonate functionality or from a polymer having NHBoc or active ester pendent groups that are subsequently transformed into the amino-bis-phosphonate comprising polymer. The amino-bis-phosphonate comprising polymers or their precursor polymers can be prepared by RAFT polymerization or by transformation of a preformed polymer. The amino-bis-phosphonate comprising polymers can be linear or branched polymers. The amino-bis-phosphonate comprising polymers can be complexed with metal ions. The metal ions can be a radionuclide and the amino-bis-phosphonate comprising polymer complexes can be used as radiotherapeutic agents. 3. The amino-bis-phosphonate polymer according to claim 1 , wherein the repeating unit is an acrylate or methacrylate claim 1 , further comprising repeating units from water soluble acrylates and/or methacrylates.11. The polymer according to claim 9 , further comprising repeating units from water soluble acrylates and/or methacrylates.21. A method for the preparation of the amino-bis-phosphonate polymer according to claim 1 , comprising:{'claim-ref': {'@idref': 'CLM-00009', 'claim 9'}, 'providing the polymer according to ;'}mixing the polymer with phosphoric acid or its equivalent, polyethylene oxide or its equivalent, and hydrochloric acid or its equivalent; and{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'neutralize at least a portion of the acid, wherein the amino-bis-phosphonate polymer according to is formed.'}22. A radiotherapeutic agent claim 1 , comprising the amino-bis-phosphonate polymer according to and at least one radionuclide complexed to the amino-bis-phosphonate polymer.23. The radiotherapeutic agent of claim 22 , wherein the radionuclide is Sm. ...

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Номер записи: 56
23-04-2020 дата публикации

POLYETHYLENEIMINE COMPOUNDS CONTAINING N-HALAMINE AND DERIVATIVES THEREOF

Номер: US20200123319A1
Автор: Dey Sanjeev K., Freund Wesley A., Srivastava Sudhanshu, Valenti Dominick J.
Принадлежит:

This invention relates to odor control molecules comprised of polyethyleneimine compounds containing N-halamine and derivatives thereof. 1. A polyethyleneimine compound comprising a plurality of amine groups , each amine group comprising a nitrogen atom , wherein:a. at least one amine group comprises a nitrogen atom directly bonded to at least one alkyleneoxy group; andb. at least one amine group comprises a nitrogen atom directly bonded to a halogen.2. The polyethylenimine compound of claim 1 , wherein the at least one alkyleneoxy group comprises three or more alkyleneoxy monomer units.4. The polyethyleneimine compound of claim 1 , wherein the halogen is selected from the group consisting of chlorine claim 1 , bromine claim 1 , fluorine claim 1 , and iodine.5. The polyethyleneimine compound of claim 4 , wherein the halogen is chlorine.6. The polyethyleneimine compound of claim 1 , wherein the polyethyleneimine compound is linear or branched.7. The polyethyleneimine compound of claim 1 , wherein the polyethyleneimine compound has a molecular weight in a range from 400 to 50 claim 1 ,000.9. The polyethyleneimine compound of claim 8 , wherein Ris an alkylamine of the formula —(CHCHNH)H claim 8 , where g is an integer equal to or greater than 1.11. The polyethyleneimine compound of claim 10 , wherein Ris chlorine.14. The polyethyleneimine compound of claim 12 , wherein Ris chlorine.15. An odor control composition comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, '(a) at least one polyethyleneimine compound of , and'}(b) at least one additional material selected from the group consisting of odor control agents and solvents.16. The odor control composition of claim 15 , wherein the odor control agents are selected from the group consisting of antimicrobial agents claim 15 , antibacterial agents claim 15 , perfumes claim 15 , activated carbon claim 15 , carbon black claim 15 , activated charcoal claim 15 , graphene claim 15 , metal organic frameworks claim 15 , ...

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Номер записи: 57
23-04-2020 дата публикации

Polyethyleneimine compounds containing n-halamine and derivatives thereof

Номер: US20200123320A1
Автор: Dominick J. Valenti, Sanjeev K. DEY, Sudhanshu Srivastava, Wesley A. Freund
Принадлежит: Milliken and Co

This invention relates to odor control molecules comprised of polyethyleneimine compounds containing N-halamine and derivatives thereof.

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Номер записи: 58
23-04-2020 дата публикации

POLYETHYLENEIMINE COMPOUNDS CONTAINING N-HALAMINE AND DERIVATIVES THEREOF

Номер: US20200123321A1
Автор: Dey Sanjeev K., Freund Wesley A., Srivastava Sudhanshu, Valenti Dominick J.
Принадлежит:

This invention relates to odor control molecules comprised of polyethyleneimine compounds containing N-halamine and derivatives thereof. 1. An article comprising:(a) at least one thermoset material, and i. at least one amine group comprises a nitrogen atom directly bonded to a functional group selected from the group consisting of alkanoyl groups, alkenoyl groups, aroyl groups, alkyl groups containing three or more carbon atoms, and aryl groups, and', 'ii. at least one amine group comprises a nitrogen atom directly bonded to a halogen., '(b) a polyethyleneimine compound comprising a plurality of amine groups, each amine group comprising a nitrogen atom, wherein2. The article of claim 1 , wherein the thermoset material is a foam.3. The article of claim 2 , wherein the foam is polyurethane foam.4. The article of claim 1 , wherein the polyethyleneimine compound further contains at least one polyalkyleneoxy chain.5. The article of claim 4 , wherein the at least one polyalkyleneoxy chain is a polymeric epoxide.6. The article of claim 5 , wherein the polymeric epoxide is selected from the group consisting of polyethylene oxides; polypropylene oxides; polybutylene oxides; oxetanes; tetrahydrafurans; copolymers of polyethylene oxides claim 5 , polypropylene oxides and polybutylene oxides; and other copolymers including block copolymers claim 5 , in which a majority of the polymeric substituent is polyethylene oxide claim 5 , polypropylene oxide and/or polybutylene oxide.7. The article of claim 1 , wherein the halogen is selected from the group consisting of chlorine claim 1 , bromine claim 1 , fluorine claim 1 , and iodine.8. The article of claim 7 , wherein the halogen is chlorine.9. The article of claim 1 , wherein the polyethyleneimine compound is linear or branched.10. The article of claim 1 , wherein the functional group is selected from the group consisting of C-Calkanoyl groups claim 1 , C-Calkenoyl groups claim 1 , aroyl groups claim 1 , C-Calkyl groups and aryl ...

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Номер записи: 59
21-05-2015 дата публикации

Hydrogen cyanide-based polymer surface coatings and hydrogels

Номер: US20150140660A1
Автор: Aylin Koegler, Helmut Thissen, Richard Evans
Принадлежит: Commonwealth Scientific and Industrial Research Organization CSIRO

The present invention provides a process of coating at least a portion of a substrate surface comprising contacting the surface with hydrogen cyanide monomeric units under conditions permitting polymerisation of the hydrogen cyanide monomeric units to form a polymer that coats the surface. Also provided is a substrate coated by a polymer according to the claimed process. Also provided is a method of forming a hydrocyanic acid-based hydrogel, the method comprising co-polymerisation in a solution, the solution comprising hydrogen cyanide monomer units and co-monomers.

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Номер записи: 60
19-05-2016 дата публикации

POLY(BETA-AMINO ALCOHOLS), THEIR PREPARATION, AND USES THEREOF

Номер: US20160137785A1
Автор: Anderson Daniel Griffith, Langer Robert S., Liu Wendy F., Ma Minglin
Принадлежит: Massachusetts Institute of Technology

A new class of poly(beta-amino alcohols) (PBAAs) has been prepared using combinatorial polymerization. The inventive PBAAs may be used in biotechnology and biomedical applications as coatings (such as coatings of films or multilayer films for medical devices or implants), additives, materials, excipients, non-biofouling agents, micropatterning agents, and cellular encapsulation agents. When used as surface coatings, these PBAAs elicited different levels of inflammation, both in vitro and in vivo, depending on their chemical structures. The large chemical diversity of this class of materials allowed us to identify polymer coatings that inhibit macrophage activation in vitro. Furthermore, these coatings reduce the recruitment of inflammatory cells, and reduce fibrosis, following the subcutaneous implantation of carboxylated polystyrene microparticles. These polymers may be used to form polyelectrolyte complex capsules for cell encapsulation. The invention may also have many other biological applications such as antimicrobial coatings, DNA or siRNA delivery, and stem cell tissue engineering. 2. The polymer of claim 1 , wherein A is substituted or unsubstituted claim 1 , branched or unbranched claim 1 , cyclic or acyclic Caliphatic claim 1 , or substituted or unsubstituted claim 1 , branched or unbranched claim 1 , cyclic or acyclic Cheteroaliphatic.3. The polymer of claim 1 , wherein A is substituted or unsubstituted claim 1 , branched or unbranched claim 1 , cyclic or acyclic Calkylene.6. The polymer of claim 1 , wherein B is substituted or unsubstituted claim 1 , branched or unbranched claim 1 , cyclic or acyclic Caliphatic claim 1 , or substituted or unsubstituted claim 1 , branched or unbranched claim 1 , cyclic or acyclic Cheteroaliphatic.7. The polymer of claim 1 , wherein B is substituted or unsubstituted claim 1 , branched or unbranched claim 1 , cyclic or acyclic Calkylene.9. The polymer of claim 1 , wherein each Rand Ris independently unsubstituted claim 1 , ...

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Номер записи: 61
28-05-2015 дата публикации

Articles Comprising Soil Absorbing Polymers and Processes for Making Same

Номер: US20150144563A1
Автор: McChain Robert Joseph, McKiernan Robin Lynn, Smith Steven Daryl
Принадлежит:

Articles containing soil adsorbing polymers, and more particularly, articles, for example nonwovens, such as paper towels, wovens, and/or sponges and/or article-forming components thereof that comprise a durably bonded soil adsorbing polymer, article-forming components used to make such articles, and processes for making same are provided. 1. A durably bonded soil adsorbing article comprising a durably bonded soil adsorbing polymer as determined by the Durably Bonded Test Method such that the durably bonded soil adsorbing article exhibits an average soil adsorption value of greater than 57 mg as measured according to the Soil Adsorption Test Method.2. The article according to wherein the article is disposable.3. The article according to wherein the article comprises a nonwoven material.4. The article according to wherein the article comprises a foam structure.5. The article according to wherein the article comprises a sponge.6. The article according to wherein the article comprises a fibrous structure comprising a hydroxyl polymer.7. The article according to wherein the hydroxyl polymer is selected from the group consisting of: polyvinyl alcohol claim 6 , cellulose claim 6 , carboxymethylcellulose claim 6 , chitin claim 6 , chitosan claim 6 , starch claim 6 , starch derivatives claim 6 , keratin claim 6 , and mixtures thereof.8. The article according to wherein the article comprises a fibrous structure comprising an amine moiety.9. The article according to wherein the soil adsorbing polymer comprises a polymer comprising a monomeric unit selected from the group consisting of: acrylamide monomeric units or derivatives thereof claim 1 , carboxylic acid-containing monomeric units claim 1 , quaternary ammonium-containing monomeric units claim 1 , other free-radically polymerizable monomeric units claim 1 , and mixtures thereof.10. The article according to wherein the soil adsorbing polymer comprises polyethyleneimine.11. The article according to wherein the soil ...

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Номер записи: 62
18-05-2017 дата публикации

PHOTOCHEMICAL CROSS-LINKABLE POLYMERS, METHODS OF MAKING PHOTOCHEMICAL CROSS-LINKABLE POLYMERS, METHODS OF USING PHOTOCHEMICAL CROSS-LINKABLE POLYMERS, AND METHODS OF MAKING ARTICLES CONTAINING PHOTOCHEMICAL CROSS-LINKABLE POLYMERS

Номер: US20170137570A1
Автор: DHENDE VIKRAM, Locklin Jason J.
Принадлежит:

Structures having a polymer composition covalently bonded to the surface of the structure, methods of attaching the polymer to the surface of the structure, methods of decreasing the amount of microorganisms formed on a structure, and the like, are disclosed. 1. A structure , comprising:a surface having a polymer, wherein the polymer comprises a linear or branched polyethylenimine polymer that has been quaternized with a hydrophobic side chain moiety and a photo cross-linkable moiety, wherein the polymer is covalently attached to the surface, and wherein the structure has an antimicrobial characteristic.2. The structure of claim 1 , wherein the antimicrobial characteristic causes a substantial amount of microorganisms to be killed.3. The structure of claim 1 , wherein the microorganism is selected from the group consisting of: gram positive bacteria claim 1 , gram negative bacteria claim 1 , protozoan claim 1 , fungi claim 1 , and algae.4. The structure of claim 1 , wherein the antimicrobial characteristic causes a microorganism growth to be inhibited or substantially inhibited.5. The structure of claim 1 , wherein the microorganism is bacterium claim 1 , and wherein the bacterium is selected from the group consisting of: gram positive bacteria claim 1 , and gram negative bacteria.6. The structure of claim 1 , wherein the structure is selected from the group consisting of: a fabric claim 1 , a textile article claim 1 , a natural fiber claim 1 , a synthetic fiber claim 1 , a porous membrane claim 1 , a plastic structure claim 1 , a oxide structure having a functionalized layer on the surface of the structure claim 1 , a metal structure having a functionalized layer on the surface of the structure claim 1 , a glass structure having a functionalized layer on the surface of the structure claim 1 , and a combination thereof.7. The structure of claim 1 , wherein the functionalized layer can have a thickness of about 2 nanometers (nm) to 1 micrometer (μm).8. The structure ...

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Номер записи: 63
10-06-2021 дата публикации

BINDERS

Номер: US20210171712A1
Автор: Pacorel Benedicte
Принадлежит:

The present invention relates to binder compositions with improved amine components, and a method of manufacturing a collection of matter bound by said binder compositions. 1. A binder composition comprising a polymeric product of at least one carbohydrate component and at least one amine component , wherein the at least one amine component comprises a substituted or unsubstituted primary diamine and/or a substituted or unsubstituted primary triamine.2. The binder composition according to claim 1 , wherein the polymeric product is a product of the at least one carbohydrate component claim 1 , the at least one amine component claim 1 , and at least one additional crosslinker which is different from the amine component.3. The binder composition according to claim 1 , wherein the substituted or unsubstituted primary diamine is a compound wherein the amino groups are separated in the molecule by a spacer group having a length of 4 to 12 atoms.4. The binder composition according to claim 3 , wherein the substituted or unsubstituted primary diamine is a compound wherein the amino groups are separated in the molecule by a spacer group having a length of 6 to 8 atoms.5. The binder composition according to claim 3 , wherein the primary diamine further contains at least one substituent within the spacer group.6. The binder composition according to claim 1 , wherein the substituted or unsubstituted primary triamine is a compound wherein at least two of the primary amino groups are separated in the molecule by a spacer group having a length of 4 to 12 atoms.7. The binder composition according to claim 6 , wherein the substituted or unsubstituted primary triamine is a compound wherein at least two of the primary amino groups are separated in the molecule by a spacer group having a length of 6 to 8 atoms.8. The binder composition according to claim 1 , wherein the at least one carbohydrate component is selected from the group consisting of monosaccharides claim 1 , disaccharides ...

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Номер записи: 64
14-08-2014 дата публикации

POLYGUANIDINE SILICATE AND USE THEREOF

Номер: US20140228528A1
Автор: Schmidt Christoph, Schmidt Nikita, Schmidt Oskar
Принадлежит: MINDINVEST HOLDINGS LTD.

A polyguanidine silicate obtainable by reacting a polymeric guanidine salt provided in an aqueous solution with an aqueous solution of a sodium and/or potassium silicate. 118-. (canceled)20. The method of wherein the polymeric guanidine salt is a polymeric bisguanidine salt.21. The method of wherein the polymeric guanidine salt is obtained by reacting a guanidine salt with an alkylene diamine and/or an oxyalkylene diamine.22. The method of wherein the polymeric guanidine salt is obtained via a reaction in which claim 19 , per mole of diamine (sum of alkylene diamine and oxyalkylene diamine) claim 19 , 0.8 to 1.2 moles of guanidine salt are used.23. The method of wherein the polymeric guanidine salt is obtained via a reaction in which the alkylene diamine and the oxyalkylene diamine are used at a molar ratio of between 4:1 and 1:4.24. The method of wherein amino groups of the alkylene diamine and/or the oxyalkylene diamine are terminal.25. The method of wherein the alkylene diamine has the general formula NH(CH)NH claim 21 , wherein n is an integer between 2 and 10 claim 21 , in particular 6.26. The method of wherein the oxyalkylene diamine has the general formula NH[(CH)O)](CH)NH claim 21 , wherein n is an integer between 2 and 5 claim 21 , in particular 2.27. The method of wherein triethylene glycol diamine (relative molecular mass: 148) claim 21 , polyoxypropylene diamine (relative molecular mass: 230) and/or polyoxyethylene diamine (relative molecular mass: 600) is/are provided as the oxyalkylene diamine.28. The method of wherein an average molecular mass of the polymeric guanidine salt ranges between 500 and 3 claim 19 ,000.29. The method of wherein a hydrochloride is provided as the salt of the guanidine.30. The method of wherein water glass is provided as the aqueous solution of a sodium and/or potassium silicate.31. The method of wherein the polyguanidine silicate is used as a biocidal agent.32. The method of wherein the polyguanidine silicate is used as an ...

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Номер записи: 65
07-05-2020 дата публикации

QUATERNARY CATIONIC POLYMERS

Номер: US20200140653A1
Автор: Cramm Jeffrey R., Dhawan Ashish, Huang Xiaodong, Moloney Jeremy, Xiong Kun, Zong Zhengang
Принадлежит: ECOLAB USA, Inc.

A cationic polymer salt composition is provided that includes a reaction product derived from reaction of a polyamine or a polyalkyleneimine and a substituted alkyl trialkyl quaternary ammonium salt. Also provided are surfactant compositions. The compositions may also include carriers, such as water, methanol, ethanol, propanol, isopropanol, butanol, isobutanol, monoethyleneglycol, an ethyleneglycol monobutyl ether, and hexylene glycol. 2. The composition of claim 1 , wherein the carrier comprises water claim 1 , an alcohol claim 1 , an aromatic hydrocarbon claim 1 , an alkylene glycol claim 1 , an alkyleneglycol alkyl ether claim 1 , or a combination thereof.3. The composition of claim 1 , wherein the carrier comprises methanol claim 1 , ethanol claim 1 , propanol claim 1 , isopropanol claim 1 , butanol claim 1 , isobutanol claim 1 , monoethyleneglycol claim 1 , ethyleneglycol monobutyl ether claim 1 , hexylene glycol or a combination thereof.4. A surfactant composition comprising an aqueous carrier and the cationic polymer salt of .5. The composition of for inhibiting corrosion at a surface claim 1 , the composition further comprising a component claim 1 , and the component comprises an organic solvent claim 1 , an additional corrosion inhibitor claim 1 , an asphaltene inhibitor claim 1 , a paraffin inhibitor claim 1 , a scale inhibitor claim 1 , an emulsifier claim 1 , a water clarifier claim 1 , a dispersant claim 1 , an emulsion breaker claim 1 , a gas hydrate inhibitor claim 1 , a biocide claim 1 , a pH modifier claim 1 , a surfactant claim 1 , or any combination thereof.6. The composition of claim 5 , wherein the component comprises the organic solvent claim 5 , and the organic solvent comprises an alcohol claim 5 , a hydrocarbon claim 5 , a ketone claim 5 , an ether claim 5 , an alkylene glycol claim 5 , a glycol ether claim 5 , an amide claim 5 , a nitrile claim 5 , a sulfoxide claim 5 , an ester claim 5 , or any combination thereof claim 5 , and the ...

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Номер записи: 66
18-06-2015 дата публикации

DRAW SOLUTES COMPRISING ALKYL AMMONIUM SALT COMPOUNDS

Номер: US20150165380A1
Автор: Han Sung Soo, Jung Bo Kyung, JUNG Won Cheol, SUH Chang Won, Yang Seung Rim
Принадлежит:

A draw solute includes a water-soluble alkyl ammonium salt compound, the water-soluble alkyl ammonium salt compound including an ionic moiety and at least two ammonium cationic moieties, the ionic moiety including an anion selected from a carbonate anion (COO), a sulfonate anion (SO), a sulfate anion (SO), a phosphonate anion (PO), and a phosphate anion (PO), and a cation selected from an alkali metal cation and an alkaline earth metal cation. 1. A draw solute comprising a water-soluble alkyl ammonium salt compound , the water-soluble alkyl ammonium salt compound including ,{'sup': −', '−', '2−', '2−', '3−, 'sub': 3', '4', '3', '4, 'an ionic moiety and at least two ammonium cationic moieties, the ionic moiety including an anion selected from a carbonate anion (COO), a sulfonate anion (SO), a sulfate anion (SO), a phosphonate anion (PO), and a phosphate anion (PO), and a cation selected from an alkali metal cation and an alkaline earth metal cation.'}2. The draw solute of claim 1 , wherein the ionic moiety includes one of —COOM claim 1 , —SOM claim 1 , —OSOM claim 1 , —OPOM claim 1 , —OPOMH claim 1 , —POM claim 1 , —OPOMe claim 1 , and a combination thereof claim 1 , wherein M is one of Li claim 1 , Na claim 1 , K and Rb claim 1 , and Me is one of Ca claim 1 , Mg claim 1 , Sr and Ba.3. The draw solute of claim 1 , wherein the at least two ammonium cationic moieties includes one of a primary ammonium cation claim 1 , a secondary ammonium cation claim 1 , a tertiary ammonium cation and a combination thereof.4. The draw solute of claim 1 , wherein the water-soluble alkyl ammonium salt compound includes:a reaction product of a polyamine compound having at least two amine groups with one of an organic acid salt having the ionic moiety together with a functional group capable of donating hydrogen to one of the at least two amine groups and an acid salt having the ionic moiety.5. The draw solute of claim 4 , whereinthe at least two amine groups are the same as or different ...

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Номер записи: 67
23-05-2019 дата публикации

FUNCTIONALIZED BILE ACIDS FOR THERAPEUTIC AND MATERIAL APPLICATIONS

Номер: US20190153019A1
Автор: Hedrick James L., Park Nathaniel H.
Принадлежит:

The subject disclosure is directed to functionalized bile acids, preparation thereof, and usage thereof for therapeutic and material applications. In one embodiment, a method of generating functionalized bile acid materials can comprise directly activating a carboxylic acid of a bile acid compound using a coupling agent comprising an amide or ester compound, thereby generating an intermediate bile acid derivative material. The method can further comprise attaching a functional group material to the intermediate bile acid derivative material by reacting the functional group material and the intermediate bile acid derivative material, thereby generating a functionalized bile acid material.

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Номер записи: 68
15-06-2017 дата публикации

NEW POLY(ETHYLENE IMINE)-BASED COPOLYMERS FOR BONDING TO AND RELEASING GENETIC MATERIAL, IN PARTICULAR DNA/RNA, AND METHOD FOR THE PRODUCTION AND USE OF SAME

Номер: US20170166697A1
Автор: Englert Christoph, GOTTSCHALDT Michael, SCHUBERT Ulrich S., TAUHARDT Lutz
Принадлежит:

Poly(ethylene imine)-based copolymers especially suited for bonding to the releasing genetic material, in particular DNA/RNA are of the general Formula I 4. The method according to claim 3 , wherein Y is —OH or —NHS claim 3 , and functionalization is introduced in the presence of (1-ethyl-3-(3-dimethylaminopropyl) carbodiimide or dicyclohexylcarbodiimide as an activating agent.6. (canceled)7. (canceled)8. The poly(ethylene imine)-based copolymers according to claim 1 , wherein the organic residue is an alkyl or an aryl group.9. The method of releasably bonding genetic material claim 1 , comprising contacting the genetic material with a poly(ethylene imine)-based copolymer of whereby the genetic material is releasably bonded to the poly(ethylene imine)-based copolymer.10. The method according to claim 9 , wherein the poly(ethylene imine)-based copolymer comprises a hydrogel.11. The method of claim 9 , wherein the poly(ethylene imine)-based copolymer comprises beads or particles.12. The method of claim 10 , wherein the poly(ethylene imine)-based copolymer comprises beads or particles.13. The method of claim 10 , wherein the hydrogel comprises a coating on a substrate.14. The method of claim 13 , wherein the substrate is made of glass.15. The method of claim 10 , wherein the hydrogel is comprised of a plurality of distinct layers of the hydrogel.16. The method according to claim 3 , wherein the genetic material comprises at least one of DNA and RNA. The invention relates to new poly(ethylene imine)-based copolymers. Furthermore, the invention also includes the method for their preparation as well as function-specific uses of the copolymers.2-(3-butenyl)-2-oxazoline is already known as a monomer (A. Gress, A. Völkel, H. Schlaad; Thio-click modification of poly[2-(3-butenyl)-2-oxazoline] Macromolecules 40, 2007, 7928-7933), which is produced by the functionalization of (2-chloroethylamine)-hydrochloride with N-succinimidyl-4-pentenate, followed by a ring closure. The ...

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Номер записи: 69
28-05-2020 дата публикации

BINDERS

Номер: US20200165389A1
Автор: Pacorel Benedicte
Принадлежит:

The present invention relates to binder compositions with improved amine components, and a method of manufacturing a collection of matter bound by said binder compositions. 1. A binder composition comprising a polymeric product of at least one carbohydrate component and at least one amine component , wherein the at least one amine component comprises a substituted or unsubstituted primary diamine and/or a substituted or unsubstituted primary triamine.2. The binder composition according to claim 1 , wherein the polymeric product is a product of the at least one carbohydrate component claim 1 , the at least one amine component claim 1 , and at least one additional crosslinker which is different from the amine component.3. The binder composition according to claim 1 , wherein the substituted or unsubstituted primary diamine is a compound wherein the amino groups are separated in the molecule by a spacer group having a length of 4 to 12 atoms.4. The binder composition according to claim 3 , wherein the substituted or unsubstituted primary diamine is a compound wherein the amino groups are separated in the molecule by a spacer group having a length of 6 to 8 atoms.5. The binder composition according to claim 3 , wherein the primary diamine further contains at least one substituent within the spacer group.6. The binder composition according to claim 1 , wherein the substituted or unsubstituted primary triamine is a compound wherein at least two of the primary amino groups are separated in the molecule by a spacer group having a length of 4 to 12 atoms.7. The binder composition according to claim 6 , wherein the substituted or unsubstituted primary triamine is a compound wherein at least two of the primary amino groups are separated in the molecule by a spacer group having a length of 6 to 8 atoms.8. The binder composition according to claim 1 , wherein the at least one carbohydrate component is selected from the group consisting of monosaccharides claim 1 , disaccharides ...

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Номер записи: 70
28-05-2020 дата публикации

POLYMER FOR DELIVERY OF BIOLOGICALLY ACTIVE MATERIALS

Номер: US20200165390A1
Автор: Cheng Wei, Lee Ashlynn, Yang Chuan, Yang Yi-Yan
Принадлежит: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

The present invention mainly relates to a polymer for delivery of biologically active materials, a complex and a method of synthesis thereof. The polymer comprises a poly(ethylene imine) and at least one monomer, each monomer comprising a modified sugar moiety, preferably galactose, comprising a sulphur atom or a nitrogen atom and a chemical moiety comprising a terminal epoxide for linking the polyethylene imine to the monomer, wherein the sulphur atom or the nitrogen atom links the modified sugar moiety to the chemical moiety. The biologically active material is preferably a gene, siRNA, mRNA or plasmid DNA. Further disclosed is the medical use of said complex in treating a disease caused by a genetic disorder, for example cancer. 1. A polymer comprising a poly(ethylene imine) and at least one monomer , each monomer comprising:(a) a modified sugar moiety comprising a sulphur atom or a nitrogen atom; and(b) a chemical moiety comprising a terminal epoxide for linking the poly(ethylene imine) to the monomer; andwherein the sulphur atom or nitrogen atom links the modified sugar moiety to the chemical moiety.2. The polymer of claim 1 , wherein the modified sugar moiety comprises at least one hydroxyl group claim 1 , and wherein at least one of the hydroxyl group is a free hydroxyl group.3. The polymer of claim 1 , wherein the modified sugar moiety comprises at least one hydroxyl group claim 1 , and wherein all of the hydroxyl groups are free.4. The polymer of any one of to claim 1 , wherein the poly(ethylene imine) is a branched poly(ethylene imine).5. The polymer of any one of to claim 1 , wherein the poly(ethylene imine) is linked to about 10 to about 97 monomers claim 1 , preferably about 20 to about 70 monomers claim 1 , and more preferably about 22 monomers claim 1 , about 41 monomers claim 1 , about 53 monomers or about 65 monomers.6. The polymer of any one of to claim 1 , wherein the polymer is water-soluble.7. The polymer of any one of to claim 1 , wherein the ...

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Номер записи: 71
08-07-2021 дата публикации

LIQUID REPELLENT

Номер: US20210206998A1
Автор: KISHIKAWA Yosuke, Kobayashi Tsutomu, SHIRAI Atsushi, TOMITAKA Shiori, UJIIE Seiji
Принадлежит:

An object of the present invention is to provide a novel liquid repellent. A liquid repellent including a poly(hydrocarbylamine) derivative, which is poly(hydrocarbylamine) substituted by one or more substituents, wherein at least one of the substituents is a substituent on an amine nitrogen in the poly(hydrocarbylamine), and is represented by the formula: 1. A liquid repellent comprising a poly(hydrocarbylamine) derivative , which is poly(hydrocarbylamine) substituted by one or more substituents , wherein at least one of the substituents is a substituent on an amine nitrogen in the poly(hydrocarbylamine) , and is represented by the formula:{'br': None, 'sup': 'ay', '—R'}{'sup': 'ay', 'in which Ris a hydroxyethyl group optionally having one or more substituents (at least one of the substituents is an alkyl group optionally having one or more substituents and into which one or more —O— moieties are optionally inserted, or an aryl group optionally having one or more substituents).'}2. The liquid repellent according to claim 1 , wherein the poly(hydrocarbylamine) derivative is a polyethyleneimine derivative claim 1 , which is polyethyleneimine substituted by one or more substituents claim 1 , wherein at least one of the substituents is a substituent on an amine nitrogen in the polyethyleneimine claim 1 , and is represented by the formula:{'br': None, 'sup': 'ay', '—R'}{'sup': 'ay', 'in which Ris a hydroxyethyl group optionally having one or more substituents (at least one of the substituents is an alkyl group optionally having one or more substituents and into which one or more —O— moieties are optionally inserted, or an aryl group optionally having one or more substituents).'}3. The liquid repellent according to claim 1 , wherein the poly(hydrocarbylamine) derivative has a straight-chain claim 1 , branched-chain or cyclic structure claim 1 , or a structure of a combination thereof.4. The liquid repellent according to claim 1 , wherein Ris a 2-hydroxyethyl group ...

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Номер записи: 72
30-06-2016 дата публикации

Ethyleneimine polymer and method for producing the same

Номер: US20160185906A1
Автор: Seiichi Suzuki, Taisuke Kasahara
Принадлежит: NIPPON SHOKUBAI CO LTD

Provided is an ethyleneimine polymer which exhibits excellent close adhesion properties and adhesive properties and has a low water content, and a method for producing the same. An ethyleneimine polymer, in which the number average molecular weight (Mn) of the ethyleneimine polymer measured by gel permeation chromatography in terms of pullulan is 13,000 or more and the value obtained by dividing the weight average molecular weight by the number average molecular weight (weight average molecular weight: Mw/number average molecular weight: Mn=degree of dispersion) of the ethyleneimine polymer is from 1.4 to 3.0.

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Номер записи: 73
29-06-2017 дата публикации

Pagophobic coating compositions, method of manufacture and methods of use

Номер: US20170183101A1
Автор: Konrad Rykaczewski, Kripa Varanasi, Sushant Anand, Xiaoda Sun
Принадлежит: Arizona Board of Regents of ASU

Some embodiments of the invention include a pagophobic coating assembly including a wick layer coupled an outer layer. The wick layer includes a fluid reservoir with an antifreeze material. The wick can be a hydrophilic or superhydrophilic material, and the outer layer can include a superhydrophobic or omniphobic material. In some embodiments, the wick includes a nylon-based polymer, and the outer layer includes a silicone or siloxane based polymer. In some embodiments of the invention, the antifreeze material includes an alkylene glycol. In some embodiments, the wick layer can enable the antifreeze material to migrate from the wick layer into the outer layer, and the outer layer is configured to enable the antifreeze to migrate to the upper surface of the outer layer. Some embodiments include an article of manufacture including the pagophobic coating assembly. Some further embodiments of the invention include a method of forming the pagophobic coating assembly.

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Номер записи: 74
04-06-2020 дата публикации

FUNCTIONALIZED BILE ACIDS FOR THERAPEUTIC AND MATERIAL APPLICATIONS

Номер: US20200172566A1
Автор: Hedrick James L., Park Nathaniel H.
Принадлежит:

The subject disclosure is directed to functionalized bile acids, preparation thereof, and usage thereof for therapeutic and material applications. In one embodiment, a method of generating functionalized bile acid materials can comprise directly activating a carboxylic acid of a bile acid compound using a coupling agent comprising an amide or ester compound, thereby generating an intermediate bile acid derivative material. The method can further comprise attaching a functional group material to the intermediate bile acid derivative material by reacting the functional group material and the intermediate bile acid derivative material, thereby generating a functionalized bile acid material. 2. The chemical compound of claim 1 , wherein the amine nucleophilic compound comprises a primary amine coupled to the carbonyl group of Structure I.3. The chemical compound of claim 2 , wherein the amine nucleophilic compound is selected from the group consisting of ethanolamine claim 2 , N claim 2 ,N-dimethylethylenediamine claim 2 , 1-(3-aminopropyl)imidazole claim 2 , benzylamine claim 2 , and 2-Amino-2-methylpropane-1 claim 2 ,3-diol.4. The chemical compound of claim 1 , wherein the amine nucleophilic compound comprises a secondary amine coupled to the carbonyl group of Structure I.5. The chemical compound of claim 4 , wherein the amine nucleophilic compound is selected from the group consisting of diethanolamine claim 4 , N claim 4 ,N claim 4 ,N′-trimethylethylenediamine claim 4 , morpholine claim 4 , 1-methylpiperazine claim 4 , and 3 claim 4 ,3′-iminobis(N claim 4 ,N-dimethylpropyl amine).6. The chemical compound of claim 1 , wherein the amine nucleophilic compound is an amine terminated polymer selected from the group consisting of polyethylene glycol and polyethyleneimine.7. The chemical compound of claim 6 , wherein the amine nucleophilic compound is the polyethylene glycol claim 6 , and wherein the polyethylene glycol has an average molecular weight of greater than or ...

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Номер записи: 75
18-09-2014 дата публикации

New polymers derived from renewably resourced lysinol

Номер: US20140275311A1
Автор: David N. Marks, Kenneth Gene Moloy, Manxue Wang, Mark A. Scialdone
Принадлежит: EI Du Pont de Nemours and Co

Disclosed are salt compositions of lysinol and dicarboxylic acids; and lysinol derived polymers including polyamide, polyimide, polyurea, cross-linked polyurea comprising urethane linkages, polyurea foams, cross-linked polyurea foams, and lysinol-epoxy thermoset.

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Номер записи: 76
29-06-2017 дата публикации

HOLE TRANSPORT COMPOSITIONS AND RELATED DEVICES AND METHODS (I)

Номер: US20170186953A1
Автор: Brown Christopher T., Chopra Neetu, KNITTEL Christopher R., Mathai Mathew, Seshadri Venkataramanan, Wang Jing, Woodworth Brian
Принадлежит:

A composition comprising: at least one compound comprising a hole transporting core, wherein the core is covalently bonded to a first arylamine group and also covalently bonded to a second arylamine group different from the first, and wherein the compound is covalently bonded to at least one intractability group, wherein the intractability group is covalently bonded to the hole transporting core, the first arylamine group, the second arylamine group, or a combination thereof, and wherein the compound has a molecular weight of about 5,000 g/mole or less. Blended mixtures of arylamine compounds, including fluorene core compounds, can provide good film formation and stability when coated onto hole injection layers. Solution processing of OLEDs is a particularly important application. 1117-. (canceled)118. A composition comprising:at least one first compound and at least one second compound different from the first,{'sub': 4', '30, 'wherein the at least one first compound comprises a hole transporting core which is a fluorene core or a biphenyl core, wherein the hole transporting core is covalently bonded to a first arylamine group and also covalently bonded to a second arylamine group, and wherein the core is further covalently bonded to at least two solubilizing groups comprising at least four carbon atoms and selected from substituted or unsubstituted Cto Calkyl or heteroalkyl groups, and wherein the solubilizing groups are optionally substituted with intractability groups;'}wherein the at least one second compound comprises a hole transporting core which is a fluorene or a biphenyl core, wherein the hole transporting core is covalently bonded to a first arylamine group and also covalently bonded to a second arylamine group, wherein the second compound further comprises at least one intractability group which may be bonded to the first arylamine group, the second arylamine group, or both;wherein the first and second compounds have molecular weight of about 5,000 g/ ...

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Номер записи: 77
06-07-2017 дата публикации

POLYAMINE ADDITION COMPOUNDS

Номер: US20170190840A1
Автор: BÖMER Jörg, Esser Andrea, Göbelt Bernd, Okkel Andreas, Omeis Jürgen, Pritschins Wolfgang, Stelz Sabine
Принадлежит: BYK-CHemie GmbH

The invention relates to polyamine addition compounds, methods for the production thereof, the use thereof as wetting agents and dispersing agents, and paints and plastic materials containing said addition compounds. 2. The polymer PAS as claimed in claim 1 , characterized in that the intermediate PA is preparable by reaction of ethylenically unsaturated ester compounds P claim 1 , in which the C═C double bond and the carbonyl double bond of the ester are conjugated claim 1 , with diamines or with amines which as well as a primary amino group comprise at least one further group that is reactive toward the ester claim 1 , or which as well as a secondary amino group comprise at least two further groups that are reactive toward the ester.3. The polymer PAS as claimed in claim 2 , characterized in that the further groups that are reactive toward the ester are primary or secondary amino groups and/or hydroxyl groups.4. The polymer PAS as claimed in claim 1 , characterized in that the intermediate PA is a dendritic polyamine which is preparable in a multistage reaction wherein in the first stage an amine A or NHand an alkyl acrylate as component P are reacted with one another and in at least one further stage the reaction product is reacted with a stoichiometric excess of diamine.5. The polymer PAS as claimed in claim 1 , characterized in that the intermediate PA is preparable by reaction of an amine A with compounds P which comprise two to six epoxide groups and/or acrylic groups.6. The polymer PAS as claimed in - claim 1 , characterized in that component S comprises an isocyanate adduct of the general formula (II){'br': None, 'sup': '1', 'Y—O—CO—NH—RNCO\u2003\u2003(II)'}{'sup': '1', 'in which Ris alike or different and is represented by a saturated or unsaturated, branched or unbranched organic radical comprising 6 to 20 carbon atoms, and Y is a monomeric or polymeric group which is not reactive toward isocyanates and which comprises one or more aliphatic, ...

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Номер записи: 78
13-07-2017 дата публикации

SOLID SORBENT MATERIALS FOR ACID-GAS SEPARATION

Номер: US20170197198A1
Автор: Coleman Luke, Lail Marty, SOUKRI Mustapha
Принадлежит: Research Triangle Institute

Solid sorbent materials have been prepared by combining polyethyleneimine (PEI) with silica precursors. The solid sorbent materials can be used, for example, for acid gas separation, gas purification, and water purification applications. Advantageously, such materials can be water stable and the capacity of such solid sorbent materials does not diminish substantially after repeated use and regeneration. 1. A solid sorbent material comprising silica and polyethyleneimine , wherein the solid sorbent material has a carbon dioxide loading capacity that is stabilized such that the carbon dioxide loading capacity is within about 30% of the carbon dioxide loading capacity of the original solid sorbent material after 50 cycles of COseparation and regeneration , and wherein the solid sorbent material is water stable.2. A solid sorbent material comprising a porous silica framework having polyethyleneimine structurally integrated within the porous silica framework.3. The solid sorbent material of claim 1 , wherein said carbon dioxide loading capacity is within about 20% of the carbon dioxide loading capacity of the original solid sorbent material after 50 cycles of COseparation and regeneration.4. The solid sorbent material of claim 1 , wherein said carbon dioxide loading capacity is within about 10% of the carbon dioxide loading capacity of the original solid sorbent material after 50 cycles of COseparation and regeneration.5. The solid sorbent material of claim 1 , wherein the mass of the solid sorbent material changes by less than about 10% after 50 cycles of COseparation and regeneration.6. The solid sorbent material of claim 1 , wherein the mass of the solid sorbent material changes by less than about 20% after 50 cycles of COseparation and regeneration.7. The solid sorbent material of claim 1 , wherein the material has an elemental nitrogen content of at least about 10% by weight.8. The solid sorbent material of claim 7 , wherein the elemental nitrogen content is within ...

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Номер записи: 79
25-09-2014 дата публикации

ALKOXYLATED POLYALKYLENEPOLYAMINES

Номер: US20140288265A1
Автор: Ebert Sophia, HUEFFER Stephan, Schaub Thomas, Strautmann Julia
Принадлежит: BASF SE

Process for the preparation of alkoxylated polyalkylenepolyamines, comprising the following steps (a) homogeneously catalyzed alcohol amination, where aliphatic amino alcohols are reacted with one another or aliphatic diamines or polyamines are reacted with aliphatic diols or polyols with the elimination of water in the presence of a homogeneous catalyst to give polyalkylenepolyamines, (b) reaction of these polyalkylenepolyamines with alkylene oxides to give alkoxylated polyalkylenepolyamines. Specific alkoxylated polyalkylenepolyamines obtainable by such processes and alkoxylated polyalkylenepolyamines and processes for their preparation. Uses of alkoxylated polyalkylenepolyamines as detergent additives, dispersants, textile auxiliaries, wood protectants, corrosion inhibitors. 1. A process for preparing an alkoxylated polyalkylenepolyamine , the process comprising: (i) aliphatic amino alcohols are reacted with one another; or', '(ii) an aliphatic diamine or polyamine is reacted with an aliphatic diol or polyol;, '(a) homogeneously catalyzed alcohol amination, wherewith the elimination of water in the presence of a homogeneous catalyst to give polyalkylenepolyamines; and(b) reaction of these polyalkylenepolyamines with alkylene oxides to give alkoxylated polyalkylenepolyamines.2. The process of claim 1 , wherein a phase separation occurs into at least one nonpolar phase and at least one polar phase after the reaction in step (a).3. The process of claim 1 , wherein the catalyst is a transition metal complex catalyst.4. The process of claim 1 , wherein the catalyst comprises a monodentate or polydentate phosphine ligand.5. The process of claim 1 , wherein the catalyst comprises a nitrogen-heterocyclic carbene ligand.6. The process of claim 1 , wherein the catalyst comprises at least one ligand selected from the group consisting of cyclopentadienyl claim 1 , substituted cyclopentadienyl claim 1 , indenyl and substituted indenyl.7. The process of claim 1 , wherein the ...

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Номер записи: 80
21-07-2016 дата публикации

Method for producing a composite plastic part (ck)

Номер: US20160207238A1
Автор: Andreas Radtke, Gaurav Ramanlal KASALIWAL, Gijsbrecht HABRAKEN, Manoranjan Prusty
Принадлежит: BASF SE

The invention relates to a method for producing a composite plastic part (CK). A first fiber material (F 1 ) is impregnated with a polyamide matrix polymer (PAM), thereby obtaining a matrix composition (MZ), onto which a surface composition (OZ) is applied, and a first plastic component (K 1 ) is obtained. In a second step, a second plastic component (K 2 ) is molded on the first plastic component (K 1 ), whereby the composite plastic part (CK) is obtained. The invention further relates to the composite plastic part (CK) which can be obtained using the method according to the invention. The invention additionally relates to the use of polyethyleneimine (PEI) for improving the impregnation of the first fiber material (F 1 ) with the polyamide matrix polymer (PAM).

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Номер записи: 81
27-06-2019 дата публикации

NOVEL PLGA-MODIFIED POLYETHYLENIMINE SELF-ASSEMBLY NANOTECHNOLOGY FOR NUCLEIC ACID AND DRUG DELIVERY

Номер: US20190194396A1
Автор: Chen Changyi, Lu Jian-Ming, Yao Qizhi
Принадлежит:

Embodiments of the invention concern copolymers and nanoparticles for use as delivery agents for one or more agents for therapy for a medical condition of humans and animals. Some of embodiments of the invention provide new reagents for biomedical research in cell culture, animal models and plants, for example. The copolymers comprise PLGA and PEI and, in some embodiments, also comprise 1-(3-aminopropyl)-4-methylpiperazine (APMP), Fc binding peptide and/or antibody. In certain embodiments, APMP-PLGA-PEI, Fc binding peptide/antibody-PLGA-PEI or Fc binding peptide/antibody-APMP-PLGA-PEI nanoparticles comprising one or more therapeutic agents are delivered to an individual in need thereof or used for biomedical research in cell cultures, animal models and plants. 1. A composition comprising:a copolymer consisting of lactide-co-glycolide and PEI;wherein single lactide-co-glycolide (LGA) units are each conjugated to primary amines of PEI through an amide linkage;wherein the w/w ratio of LGA to PEI is 0.5:1 to 5:1; andat least one therapeutic and/or diagnostic agent selected from the group consisting of a nucleic acid, protein, peptide, small molecule, antigen, vaccine, delivery agent, antibody, and mixtures thereof.2. The composition of claim 1 , wherein the composition is in the form of a microparticle or a nanoparticle.3. The composition of claim 1 , wherein the copolymer is chemically conjugated to a linker.4. The composition of claim 3 , wherein the linker is a polyethylene glycol (PEG) linker.5. The composition of claim 4 , wherein the PEG linker is Maleimide-PEG-NHS.6. The composition of claim 3 , wherein the linker is chemically conjugated to Fc binding peptide or antibody for specific delivery.7. The composition of claim 1 , wherein the nucleic acid is DNA.8. The composition of claim 7 , wherein the DNA is double stranded claim 7 , single stranded claim 7 , or a mixture thereof.9. The composition of claim 7 , wherein the DNA is an oligonucleotide.10. The ...

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Номер записи: 82
20-07-2017 дата публикации

SYNTHESIS OF LINEAR POLYETHYLENEIMINE BY LIVING ANIONIC POLYMERIZATION

Номер: US20170204224A1
Автор: Mbarushimana Pierre Canisius, Reisman Louis, Rupar Paul A.
Принадлежит:

Disclosed herein are methods for the productions of linear polyethyleneimine using living anionic polymerization of appropriately functionalized aziridine monomers. 3. The process according to claim 1 , wherein the anionic initiator comprises LDA claim 1 , KHDMS claim 1 , LiHDMS claim 1 , NaHDMS claim 1 , LiTMP claim 1 , NaOBu claim 1 , KOBu claim 1 ,4. The process according to claim 1 , wherein n+m is an integer greater than 200.5. The process according to claim 1 , wherein n+m is an integer greater than 400.6. The process according to claim 1 , wherein n+m is an integer greater than 600.7. The process according to claim 1 , wherein Rand Rare both 2-nitrophenyl.8. The process according to claim 1 , wherein Rand Rare different and are each selected from C-Calkyl claim 1 , C-Ccycloalkyl claim 1 , or substituted or unsubstituted phenyl.9. The process according to claim 8 , wherein Ris methyl Ris Calkyl.10. The process according to claim 9 , wherein Ris sec-butyl.11. A linear polyethyleneimine claim 9 , characterized by a Mn >5 claim 9 ,000; a polydispersity of no more than 1.10 claim 9 , further characterized in that the polyethyleneimine does not contain any amide functional groups.12. The linear polyethyleneimine according to claim 11 , having a M>10 claim 11 ,000.13. The linear polyethyleneimine according to claim 11 , having a M>20 claim 11 ,000. This application claims the benefit of U.S. Provisional Application 62/278,836, filed Jan. 14, 2016, the entire contents of which are hereby incorporated by reference.The invention is generally directed to the synthesis of linear polyethyleneimine via polymerization of functionalized aziridine monomers.Polyethyleneimine (PEI) is an important polymer that is useful in a wide range of commercial, biomedical, and research applications. PEI has been used as an excipient for pharmaceutical formulations, as a gene transfection agent, as an interface modifier for organic electronics, as a component in ion exchange resins, as a ...

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Номер записи: 83
28-07-2016 дата публикации

Cationic polyamines for treatment of viruses

Номер: US20160213707A1
Автор: Chuan Yang, Ichiyama Koji, James L. Hedrick, Naoki Yamamoto, Yi Yan Yang
Принадлежит: Agency for Science Technology and Research Singapore, International Business Machines Corp, NATIONAL UNIVERSITY OF SINGAPORE

Antiviral cationic polyamines were prepared by modifying polyethylenimines with N-acylating agents that introduce a side chain comprising one or more carbons and at least one alcohol hydroxy group. The cationic polyamines can have a linear or branched polyethylenimine backbone structure. Preferably, the cationic polyamines comprise pendant monosaccharide groups, which can be introduced via a cyclic carbonate comprising a pendant protected monosaccharide (e.g., mannose) group. The cationic polyamines can be active and selective against a broad spectrum of viruses at low concentrations, and are generally non-toxic.

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Номер записи: 84
06-08-2015 дата публикации

Compositions for the delivery of rna and drugs into cells

Номер: US20150216991A1
Автор: Swati Biswas, Vladimir Torchilin
Принадлежит: Norheastern University

Provided is a co-polymer of formula A-L-D, or a pharmaceutically acceptable salt thereof, wherein A is a linear, branched or dendritic polyamine; D is a lipid; and L is a linker comprising a water soluble polymer; wherein L is connected to A at a first end through a first covalent bond and connected to D at a second end through a second covalent bond.

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Номер записи: 85
09-10-2014 дата публикации

SYNTHESIS AND APPLICATION REACTIVE ANTIMICROBIAL COPOLYMERS FOR TEXTILE FIBERS

Номер: US20140302302A1
Автор: Locklin Jason J.
Принадлежит:

Embodiments of the present disclosure, in one aspect, relate to polymer compositions, methods of making polymer compositions, structures (e.g., textile articles) having the polymer composition covalently bonded to the structure, methods of attaching the polymer to the surface of the structure having —OH functionality (e.g., C—OH), methods of decreasing the amount of microorganisms formed on a structure, and the like. 2. The polymer of claim 1 , wherein R1 has the formula of CH claim 1 , where q is 1 to 25 claim 1 , and R2 has the formula CH claim 1 , where r is 1 to 25.3. The polymer of claim 1 , wherein the A is selected from the group consisting of: chloride claim 1 , bromide claim 1 , iodide claim 1 , an alkyl sulfate anion claim 1 , tetrafluoroborate claim 1 , tosylate claim 1 , sulfate claim 1 , chlorate claim 1 , and a combination thereof.5. The structure of claim 4 , wherein the structure is selected from the group consisting of: a fabric claim 4 , a textile article claim 4 , a natural fiber claim 4 , a synthetic fiber claim 4 , a porous membrane claim 4 , and a combination thereof.6. The structure of claim 4 , wherein R1 has the formula of CH claim 4 , where q is 1 to 25 claim 4 , and R2 has the formula CH claim 4 , where r is 1 to 25 claim 4 , and wherein the A is selected from the group consisting of: chloride claim 4 , bromide claim 4 , iodide claim 4 , an alkyl sulfate anion claim 4 , tetrafluoroborate claim 4 , tosylate claim 4 , sulfate claim 4 , chlorate claim 4 , and a combination thereof.8. The method of claim 7 , wherein preparing the pendant group includes:treating bromoethanol with mercaptophenol to obtain 4-(2-hydroxyethylsulfanyl) phenol;{'sub': 5', '4', '2', '4, 'reacting the obtained product with 2KHSO.KHSO.KSOto yield 4-(2-hydroxyethansulfonyl) phenol; and'}reacting the obtained intermediate with dibromohexane to yield 2-(4-(6-bromohexyloxy)phenylsulfonyl) ethanol to yield the pendant group.9. The method of claim 8 , wherein the pendant ...

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Номер записи: 86
04-07-2019 дата публикации

BINDERS

Номер: US20190202987A1
Автор: Pacorel Benedicte
Принадлежит:

The present invention relates to binder compositions with improved amine components, and a method of manufacturing a collection of matter bound by said binder compositions. 1. A binder composition comprising a polymeric product of at least one carbohydrate component and at least one amine component , wherein the at least one amine component comprises a substituted or unsubstituted primary diamine and/or a substituted or unsubstituted primary triamine.2. The binder composition according to claim 1 , wherein the polymeric product is a product of the at least one carbohydrate component claim 1 , the at least one amine component claim 1 , and at least one additional crosslinker which is different from the amine component.3. The binder composition according to claim 1 , wherein the substituted or unsubstituted primary diamine is a compound wherein the amino groups are separated in the molecule by a spacer group having a length of 4 to 12 atoms.4. The binder composition according to claim 3 , wherein the substituted or unsubstituted primary diamine is a compound wherein the amino groups are separated in the molecule by a spacer group having a length of 6 to 8 atoms.5. The binder composition according to claim 3 , wherein the primary diamine further contains at least one substituent within the spacer group.6. The binder composition according to claim 1 , wherein the substituted or unsubstituted primary triamine is a compound wherein at least two of the primary amino groups are separated in the molecule by a spacer group having a length of 4 to 12 atoms.7. The binder composition according to claim 6 , wherein the substituted or unsubstituted primary triamine is a compound wherein at least two of the primary amino groups are separated in the molecule by a spacer group having a length of 6 to 8 atoms.8. The binder composition according to claim 1 , wherein the at least one carbohydrate component is selected from the group consisting of monosaccharides claim 1 , disaccharides ...

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Номер записи: 87
04-08-2016 дата публикации

HYDROPHOBICALLY MODIFIED POLYAMINE SCALE INHIBITORS

Номер: US20160221850A1
Автор: Heitner Howard, Spitzer Donald P.
Принадлежит: CYTEC TECHNOLOGY CORP.

Hydrophobically modified Si-containing polyamines are useful for treating scale in industrial process streams. Preferred hydrophobically modified Si-containing polyamines are particularly useful for treating aluminosilicate scale in difficult-to-treat industrial process streams, such as in the Bayer alumina process streams, nuclear waste streams and kraft paper mill effluent streams. 1. A composition comprising a polymeric reaction product of:a polyamine,a first nitrogen-reactive compound, anda second nitrogen-reactive compound;wherein:{'sup': 4', '4', '4, 'sub': 2', '2', '1', '8', '6', '10, 'the polyamine comprises a (NR)-J-(NR) moiety, wherein J is an optionally substituted hydrocarbyl fragment comprising from about 2 to about 40 carbons, and each Ris independently H, optionally substituted C-Calkyl, or optionally substituted C-Caryl;'}{'sub': 3', '1', '20', '6', '12', '7', '20', '2', '20', '4', '1', '20', '6', '12', '7', '20', '2', '20, 'sup': 1', '1, 'the first nitrogen-reactive compound comprises a —Si(OR)group and a nitrogen-reactive group, wherein R is H, optionally substituted C-Calkyl, optionally substituted C-Caryl, optionally substituted C-Caralkyl, optionally substituted C-Calkenyl, Group I metal ion, Group II metal ion, or NR, wherein each Ris independently selected from H, optionally substituted C-Calkyl, optionally substituted C-Caryl, optionally substituted C-Caralkyl, and optionally substituted C-Calkenyl; and'}at least one of the polyamine and the second nitrogen-reactive compound comprises an optionally substituted hydrocarbyl radical comprising from about 2 to about 40 carbons.2. The composition of claim 1 , wherein the second nitrogen-reactive compound comprises at least two nitrogen-reactive moieties.4. The composition of claim 1 , wherein the polymeric reaction product has a weight average molecular weight of at least about 500.5. A method for reducing or eliminating scale in an industrial process comprising adding a composition according to ...

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Номер записи: 88
11-07-2019 дата публикации

FUNCTIONALIZED BILE ACIDS FOR THERAPEUTIC AND MATERIAL APPLICATIONS

Номер: US20190211051A1
Автор: Hedrick James L., Park Nathaniel H.
Принадлежит:

The subject disclosure is directed to functionalized bile acids, preparation thereof, and usage thereof for therapeutic and material applications. In one embodiment, a method of generating functionalized bile acid materials can comprise directly activating a carboxylic acid of a bile acid compound using a coupling agent comprising an amide or ester compound, thereby generating an intermediate bile acid derivative material. The method can further comprise attaching a functional group material to the intermediate bile acid derivative material by reacting the functional group material and the intermediate bile acid derivative material, thereby generating a functionalized bile acid material. 1. A method for a synthesis of a functionalized bile acid material , the method comprising:directly activating a carboxylic acid of glycocholic acid using a coupling agent that comprises pentafluorophenyl carbonate, thereby generating an intermediate bile acid derivative material; andcovalently bonding a nucleophile to the intermediate bile acid derivative material, wherein the nucleophile comprises an amine functional group, thereby generating the functionalized bile acid material.2. The method of claim 1 , wherein the nucleophile comprises a small molecule amine selected from a group consisting of ethanolamine claim 1 , N claim 1 ,N-dimethylethylenediamine claim 1 , 1-(3-aminopropyl)imidazole claim 1 , benzylamine claim 1 , or 2-amino-2-methylpropane-1 claim 1 ,3-diol claim 1 , diethanolamine claim 1 , N claim 1 ,N claim 1 ,N′-trimethylethylenediamine claim 1 , morpholine claim 1 , 1-methylpiperazine claim 1 , and 3 claim 1 ,3′-iminobis(N claim 1 ,N-dimethylpropyl) amine.3. The method of claim 1 , wherein the amine functional group is selected from a group consisting of a primary amine group and a secondary amine group claim 1 , and wherein the functionalized bile acid material comprises a bile acid amide.4. The method of claim 3 , wherein the method further comprises:attaching a ...

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Номер записи: 89
11-07-2019 дата публикации

POROUS/NANOPOROUS PHT

Номер: US20190211152A1
Автор: Boday Dylan J., GARCIA Jeannette M., Hedrick James L., Wojtecki Rudy J.
Принадлежит:

In an embodiment, a polymeric material includes a plurality of hemiaminal units bonded together by a first linkage and a second linkage, wherein the first linkage is thermally stable and resistant to bases and the second linkage is thermally degradable and degradable by a base. In another embodiment, a method of forming nanoporous materials includes forming a polymer network with a chemically removable portion. The chemically removable portion may be polycarbonate polymer that is removable on application of heat or exposure to a base, or a polyhexahydrotriazine (PHT) or polyhemiaminal (PHA) polymer that is removable on exposure to an acid. Removing any portion of the polymer results in formation of nanoscopic pores as polymer chains are decomposed, leaving pores in the polymer matrix. 1. A polymeric material comprising a plurality of hemiaminal units bonded together by a first linkage and a second linkage , wherein the first linkage is thermally stable and resistant to bases and the second linkage is thermally degradable and degradable by a base.2. The polymeric material of claim 1 , wherein the second linkage is a polycarbonate or polyester linkage.3. The polymeric material of claim 2 , wherein the first linkage is a dianiline linkage.5. The polymeric material of claim 4 , wherein R includes an aromatic diamine.6. The polymeric material of claim 5 , wherein the aromatic diamine is paraphenylenedianiline.12. The polymeric material of claim 11 , wherein the first linkage is a dianiline linkage.13. The polymeric material of claim 11 , wherein R includes an aromatic diamine.14. The polymeric material of claim 13 , wherein the aromatic diamine is paraphenylenedianiline.20. The polymeric material of claim 19 , wherein R includes an aromatic diamine. This is a divisional application of co-pending U.S. patent application Ser. No. 15/399,365 filed Jan. 5, 2017 which is a divisional application of co-pending U.S. patent application Ser. No. 14/516,117 filed Oct. 16, 2014, ...

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Номер записи: 90
19-08-2021 дата публикации

BINDERS

Номер: US20210253795A1
Автор: Pacorel Benedicte
Принадлежит:

The present invention relates to binder compositions with improved amine components, and a method of manufacturing a collection of matter bound by said binder compositions. 1. A binder composition comprising a polymeric product of at least one carbohydrate component and at least one amine component , wherein the at least one amine component comprises a substituted or unsubstituted primary diamine and/or a substituted or unsubstituted primary triamine.2. The binder composition according to claim 1 , wherein the polymeric product is a product of the at least one carbohydrate component claim 1 , the at least one amine component claim 1 , and at least one additional crosslinker which is different from the amine component.3. The binder composition according to claim 1 , wherein the substituted or unsubstituted primary diamine is a compound wherein the amino groups are separated in the molecule by a spacer group having a length of 4 to 12 atoms.4. The binder composition according to claim 3 , wherein the substituted or unsubstituted primary diamine is a compound wherein the amino groups are separated in the molecule by a spacer group having a length of 6 to 8 atoms.5. The binder composition according to claim 3 , wherein the primary diamine further contains at least one substituent within the spacer group.6. The binder composition according to claim 1 , wherein the substituted or unsubstituted primary triamine is a compound wherein at least two of the primary amino groups are separated in the molecule by a spacer group having a length of 4 to 12 atoms.7. The binder composition according to claim 6 , wherein the substituted or unsubstituted primary triamine is a compound wherein at least two of the primary amino groups are separated in the molecule by a spacer group having a length of 6 to 8 atoms.8. The binder composition according to claim 1 , wherein the at least one carbohydrate component is selected from the group consisting of monosaccharides claim 1 , disaccharides ...

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Номер записи: 91
19-08-2021 дата публикации

HIGH-PERFORMANCE TRIPLE-CROSSLINKED POLYMER AND PREPARATION METHOD THEREOF

Номер: US20210253805A1
Автор: Chang Baoxuan, Chang Guanjun, Xu Yewei, Yang Li, Yang Shien, Yuan Rui
Принадлежит:

A high-performance triple-crosslinked polymer and a preparation method thereof are provided. The polymer is obtained by curing and cross-linking a monomer having two epoxy groups, a cross-linking monomer and a functional monomer. The polymer contains a cross-linking network formed by covalent bonds and two types of multi-level hydrogen bonds with different strengths. The interaction strength between the covalent bonds and the two types of hydrogen bonds decreases in a gradient. The dilemma of the strength-ductility tradeoff in a high-performance polymer is overcome by forming a triple-crosslinked network with covalent bonds and multi-level hydrogen bonds with different strengths in the polymer. The dynamic and hierarchical hydrogen bonds are broken and recombined timely and continuously to concurrently maintain the complete structure of the polymer network and enable the polymer network to quickly respond to the transmission and dissipation of the external environment. 1. A high-performance triple-crosslinked polymer , wherein the high-performance triple-crosslinked polymer is obtained by curing and cross-linking a monomer having two epoxy groups , a cross-linking monomer and a functional monomer , and the high-performance triple-crosslinked polymer contains a cross-linking network formed by covalent bonds and two types of multi-level hydrogen bonds with different strengths , and an interaction strength of the covalent bonds and the two types of hydrogen bonds decreases in a gradient.2. The high-performance triple-crosslinked polymer according to claim 1 , wherein a first part of the two types of multi-level hydrogen bonds with the different strengths are formed between the functional monomers claim 1 , and a second part of the two types of multi-level hydrogen bonds with the different strengths are formed between the functional monomer and the monomer having the two epoxy groups; a first part of the covalent bonds are formed between the monomer having the two epoxy ...

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Номер записи: 92
16-07-2020 дата публикации

Enhancing the Antimicrobial Activity of Biocides with Polymers

Номер: US20200221694A1
Автор: Garcia Marcos Alejandra, Hazenkamp Menno, Huffer Stephan, Purschwitz Janina
Принадлежит:

Disclosed are compositions comprising a) an antimicrobial agent, which is selected from the group consisting of biocides containing halogen atoms and/or containing phenolic moieties, formic acid, chlorine dioxide, chlorine dioxide generating compounds, dialdehydes; components containing an antimicrobial metal such as antimicrobial silver, and b) a polyamine, especially a polyethylenimine. The polyamine is effective as a booster for the antimicrobial agent. 115.-. (canceled)16. A liquid composition comprising:a) phenoxyethanol, andb) a polyamine; (I) the phenoxyethanol is present in an amount from 0.001% to 1% b.w. relative to the liquid composition total weight, and the polyamine is present in an amount from 0.001% to 1% b.w. relative to the liquid composition total weight; or', '(II) the phenoxyethanol is present in an amount from 0.001% to 5% b.w. relative to the liquid composition total weight, and the polyamine is present in an amount from 0.001 to 10 parts by weight relative to the phenoxyethanol, the liquid composition further comprises a surfactant, and the liquid composition is in the form of an aqueous composition further comprising water., 'wherein one of conditions (I) or (II) also apply to the liquid composition17. The liquid composition of claim 16 , wherein condition (I) applies to the liquid composition.18. The liquid composition of claim 16 , wherein condition (II) applies to the liquid composition.19. The liquid composition of claim 18 , wherein the water is present in the aqueous composition in an amount of at least 50% b.w. relative to the liquid composition total weight.20. The liquid composition of claim 16 , wherein:the phenoxyethanol is present in an amount from 50 ppm to 10000 ppm relative to the liquid composition total weight; andthe polyamine is present in an amount from 10 ppm to 1000 ppm relative to the liquid composition total weight.21. The liquid composition of claim 16 , wherein the liquid composition is in the form of a liquid home ...

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Номер записи: 93
16-07-2020 дата публикации

Oxazoline Modified Dispersants

Номер: US20200224117A1
Автор: Carranza Arturo, Jiang Sheng, Loper John
Принадлежит:

The present disclosure relates to oxazoline modified lubricant additives that have dispersant properties and lubricating oil compositions including such dispersant lubricant additives. The disclosure also relates to the use of lubricant compositions comprising the additives of the disclosure for improving the soot or sludge handling characteristics of an engine lubricant composition while providing robust and consistent frictional performance at the same time. 1. A lubricant dispersant comprising:a reaction product of a hydrocarbyl substituted succinamide or succinimide dispersant with an oxazoline or an oxazoline derivative to form the lubricant dispersant having one or more pendant hydrocarbyl amide groups;wherein the hydrocarbyl substituted succinamide or succinimide dispersant is derived from a hydrocarbyl substituted acylating agent reacted with a polyalkylene polyamine; andwherein the hydrocarbyl substituent of the succinamide or the succinimide dispersant is a linear or branched hydrocarbyl group having a number average molecular weight of about 250 to about 5,000 as measured by GPC using polystyrene as a calibration reference.2. The lubricant dispersant of claim 1 , wherein the oxazoline or the oxazoline derivative includes hydrocarbyl pendant groups in one of oxazoline ring positions 2 claim 1 , 4 claim 1 , 5 claim 1 , or combinations thereof.3. The lubricant dispersant of claim 2 , wherein the hydrocarbyl pendant groups are selected from C1 to C32 hydrocarbyl claim 2 , substituted or unsubstituted aromatic claim 2 , substituted or unsubstituted hetrocyclic aromatic claim 2 , hydroxyalkyl claim 2 , and mixtures thereof.4. The lubricant dispersant of claim 1 , wherein the oxazoline or the oxazoline derivative is selected from the group consisting of 2-ethyl-2-oxazoline; 2-methyl-2-oxazoline; 2-benzyl-4 claim 1 ,4-dimethyl-2-oxazoline; 2-ethyl-4 claim 1 ,4-dimethyl-2-oxazoline; 2 claim 1 ,4 claim 1 ,4-trimethyl-2-oxazoline; 4 claim 1 ,4-dimethyl-2-oxazoline; ...

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Номер записи: 94
23-08-2018 дата публикации

COMPOSITIONS FOR INTRODUCING NUCELIC ACID INTO CELLS

Номер: US20180236090A1
Автор: Dohmen Christian, Plank Christian, Rudolph Carsten
Принадлежит:

The present invention relates to polymers comprising a characteristic combination of alkylene amine moieties which are useful as vehicles for transfecting a cell with a nucleic acid. The present invention furthermore relates to a composition comprising a nucleic acid and such a polymer, and to a method of transfecting a cell using said composition. Furthermore, the present invention relates to pharmaceutical compositions and uses. 2. The copolymer of claim 1 , which is a branched or dendritic copolymer comprising one or more types of repeating units selected from repeating units (a2) claim 1 , (b2) and (b4).3. The copolymer of claim 1 , which is a linear copolymer comprising repeating units (a1) and (b1).4. The copolymer of any of to claim 1 , wherein the repeating units (a) and (b) account for 80 mol % or more of all repeating units in the copolymer.5. The copolymer of any of to claim 1 , wherein repeating units (a) selected from (a1) and (a2) and repeating units (b) selected from (b1) and (b2) account for 80 mol % or more of all repeating units in the copolymer.6. The copolymer of any of to claim 1 , wherein the terminal groups of the copolymer comprise one or more types of groups (c) independently selected from groups of the formulae (c1) to (c3):{'br': None, 'sub': 2', '2', '2, '—CH—CH—NH\u2003\u2003(c1)'}{'br': None, 'sub': 2', '2', '2', '2, '—CH—CH—CH—NH\u2003\u2003(c2)'}{'br': None, 'sub': 2', '2', '2', '2', '2, '—CH—CH—CH—CH—NH\u2003\u2003(c3).'}7. The copolymer of any of to claim 1 , wherein the molar ratio of the repeating units (a) to the repeating units (b) lies within the range of 0.8/1.0 to 1.0/0.8.8. The copolymer of any of to claim 1 , which is obtainable by polymerizing a monomer mixture comprising aziridine claim 1 , azetidine claim 1 , and optionally pyrrolidine.9. A composition comprising a nucleic acid and a copolymer in accordance with any of to .10. The composition of claim 9 , wherein the nucleic acid is mRNA.11. The composition of or claim 9 ...

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Номер записи: 95
06-11-2014 дата публикации

Substrate-Independent Layer-By-Layer Assembly Using Catechol-Functionalized Polymers

Номер: US20140329967A1
Автор: Hamming Lesley, Lee Haeshin, LEE Yuhan, Liu Zhongqiang, Messersmith Phillip B.
Принадлежит: Northwestern University

The present invention provides a simple, non-destructive and versatile method that enables layer-by-layer (LbL) assembly to be performed on virtually any substrate. A novel catechol-functionalized polymer which adsorbs to virtually all surfaces and can serve as a platform for LbL assembly in a surface-independent fashion is also provided. 1. A catechol-functionalized polymer comprising the structure:wherein “n” has a value in the range from 10 to 10,000; andwherein “x” has a value in the range from 1 to 5,000. This application is a divisional of U.S. application Ser. No. 14/017,844 filed Sep. 4, 2013, which is a divisional of U.S. application Ser. No. 13/622,136, filed Sep. 18, 2012, which issued as U.S. Pat. No. 8,551,568 on Oct. 8, 2013, which is a continuation of U.S. application Ser. No. 12/267,822, filed Nov. 10, 2008, which issued as U.S. Pat. No. 8,293,867 on Oct. 23, 2012, each of which claim the benefit of U.S. Provisional Application No. 60/986,847, filed Nov. 9, 2007. Each of these applications is hereby incorporated by reference in their entirety for all purposes.This invention was made with government support under grant numbers DE014193 and DE018350 awarded by the National Institutes of Health. The government has certain rights in the invention.Layer-by-layer (LbL) assembly allows one to create multifunctional films on surfaces while maintaining the bulk properties of the individual surfaces [1]. The method relies on sequential adsorption of polymers onto bulk surfaces from solution, giving rise to complex multifunctional, multilayered films. LbL assembly is simple to implement and offers extensive control over film properties and composition during stepwise adsorption of components.Although the vast majority of LbL films are built from polyelectrolytes via electrostatic interaction between layers, more recently LbL films have been made with hydrogen bonding of polymers [2], and other building blocks such as inorganic nanoparticles, giving access to ...

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Номер записи: 96
24-08-2017 дата публикации

Ligand functionalized polymers

Номер: US20170240591A1
Автор: Catherine A. Bothof, Erin A. Satterwhite, George W. Griesgraber, James I. Hembre, Jerald K. Rasmussen, Kannan Seshadri, Louis C. Haddad, Robert T. Fitzsimons, Jr., Yi He
Принадлежит: 3M Innovative Properties Co

Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.

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Номер записи: 97
13-11-2014 дата публикации

New polymers derived from renewably resourced lysinol

Номер: US20140336353A1
Автор: Kenneth Gene Moloy, Manxue Wang, Mark A. Scialdone
Принадлежит: EI Du Pont de Nemours and Co

Disclosed are salt compositions of lysinol and dicarboxylic acids; and lysinol derived polymers including polyamide, polyimide, polyurea, cross-linked polyurea comprising urethane linkages, polyurea foams, cross-linked polyurea foams, and lysinol-epoxy thermoset.

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Номер записи: 98
31-08-2017 дата публикации

ETHLENEIMINE POLYMER AND METHOD FOR PRODUCING SAME

Номер: US20170247511A1
Автор: Kasahara Taisuke, SUZUKI Seiichi
Принадлежит:

Provided is an ethyleneimine polymer which exhibits excellent close adhesion properties and adhesive properties and is unlikely to form a gel-like film, and a method for producing the same. An ethyleneimine polymer, wherein a number average molecular weight (Mn) of the ethyleneimine polymer measured by gel permeation chromatography in terms of pullulan is 13,000 or more, a degree of dispersion of the ethyleneimine polymer is greater than 3.0 and 5.0 or less, and a water content in the ethyleneimine polymer is from 3 to 35% by weight. 1. An ethyleneimine polymer , whereina number average molecular weight (Mn) of the ethyleneimine polymer measured by gel permeation chromatography in terms of pullulan is 13,000 or more,a degree of dispersion of the ethyleneimine polymer is greater than 3.0 and 5.0 or less, anda water content in the ethyleneimine polymer is from 3 to 35% by weight.2. A method for producing an ethyleneimine polymer , the method comprising:polymerizing ethyleneimine under a temperature condition of higher than 90° C. and 150° C. or lower in the presence of water at from 1.0 to 40% by mass with respect to 100% by mass of the ethyleneimine and a catalyst at from 0.3 to 5% by mass with respect to 100% by mass of the ethyleneimine.3. The method for producing an ethyleneimine polymer according to claim 2 , whereinthe catalyst isa water-soluble organic compound having at least one halogen element and a hydrophilic substituent ora water-soluble inorganic acid containing a halogen element.4. The method for producing an ethyleneimine polymer according to claim 2 , further comprising adjusting a water content after the polymerization.5. The method for producing an ethyleneimine polymer according to claim 2 , wherein a method for adding the catalyst is continuous addition.6. An adhesion promoter for film printing ink comprising:{'claim-ref': [{'@idref': 'CLM-00001', 'claim 1'}, {'@idref': 'CLM-00002', 'claim 2'}], 'the ethyleneimine polymer according to or an ...

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Номер записи: 99
17-09-2015 дата публикации

HYDROXYLATED POLYAMINE DERIVATIVES AS TRANSFECTION REAGENTS

Номер: US20150259678A1
Автор: Dreher Christina, Panzner Steffen, Reinsch Christian, Wendisch Volkmar
Принадлежит:

The invention provides hydroxylated polyamine derivatives, their use for the transfection of polyanions into cells, and a method of transfecting cells with a polyanion, comprising mixing said polyanion with said hydroxylated polyamine derivative in a buffer and treating said cells with the mixture obtained in the previous step. 1. Use of a polyamine derivative for the transfection of polyanions into cells , said polyamine comprising:a polyamine moiety comprising a plurality of amino groups;a plurality of hydroxylated substituents comprising a hydroxyl group bonded via a hydrophobic linker to amino groups of said polyamine moiety; anda plurality of hydrophobic substituents bonded to amino groups of said polyamine moiety;said hydrophobic linker having a log P of from 2 to 20 determined for a compound obtainable from said linker by replacing bonds of said linker to the hydroxyl group and the amino group of said polyamine by bonds to hydrogen atoms; andsaid hydrophobic substituent having a log P of from 1.5 to 20 determined for a compound obtainable from said hydrophobic substituent by replacing the bond of said hydrophobic substituent to an amino group of said polyamine moiety by a bond to a hydrogen atom.2. The use according to claim 1 , wherein each of said hydroxylated substituents comprises from 4 to 40 carbon atoms claim 1 , preferably from 4 to 20 carbon atoms claim 1 , and more preferably from 6 to 12 carbon atoms claim 1 , and each of said hydrophobic linkers may comprise from 1 to 3 heteroatoms selected from O claim 1 , N claim 1 , and S.3. The use according to claim 1 , wherein each of said hydrophobic substituents comprises at least 2 carbon atoms claim 1 , preferably from 3 to 40 carbon atoms claim 1 , and may comprise from 1 to 3 heteroatoms selected from O claim 1 , N claim 1 , and S provided said hydrophobic substituent has at least 6 carbon atoms.4. The use according to claim 1 , wherein a polyamine moiety of said polyamine derivative is selected from ...

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Номер записи: 100