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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 22. Отображено 22.
04-04-2023 дата публикации

Water transparency inversion method and system based on remote sensing image

Номер: CN115909053A
Автор: ZHANG DIANJUN, XIAO YUN, JIANG CHEN, ZHAN JIE, WANG YI, LI ZUKUN, OUYANG ZHUXIN
Принадлежит:

The invention discloses a water transparency inversion method and system based on a remote sensing image, and relates to the field of water color remote sensing, and the water transparency inversion method comprises the steps: obtaining a water remote sensing image; preprocessing the water body remote sensing image to obtain the reflectivity of the water body remote sensing image; determining the remote sensing reflectivity of the water body according to the reflectivity of the water body remote sensing image; according to the remote sensing reflectivity of the water body, the inherent optical characteristics of the water body are obtained through a QAA algorithm, and the inherent optical characteristics of the water body comprise an absorption coefficient and a backscattering coefficient; determining a diffusion attenuation coefficient of a semi-analysis model according to the inherent optical characteristics of the water body; determining the FUI index of the water body according to the ...

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Номер записи: 1
19-09-2019 дата публикации

COMPOSITION FOR PURIFICATION OF BIOFLUIDS

Номер: WO2019174560A1
Автор: JIANG, Chen, SUN, Tao
Принадлежит:

Disclosed is a composition for the purification of biofluids, for example, for hemodialysis and peritoneal dialysis, wherein same comprises a penetrant and a toxin-removal reagent that can remove toxins from biofluids under osmotic exchange conditions. Provided are a dialysis solution and a kit comprising the aforementioned composition, a method for removing toxins from biofluids using the aforementioned composition, and a method for treating toxin-related diseases.

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Номер записи: 2
07-04-2023 дата публикации

Stimulus-responsive nanogel based on prodrug and preparation method thereof

Номер: CN115919748A
Автор: JIANG CHEN, ZHOU ZHENG, SUN TAO
Принадлежит:

The invention belongs to the technical field of stimuli-responsive pharmaceutical preparations, and particularly relates to a prodrug-based stimuli-responsive nanogel and a preparation method thereof. The preparation method comprises the following steps: reacting a drug containing reactive hydrogen with a phenylboronic acid compound to obtain an intermediate with a phenylboronic acid group, and esterifying the intermediate to obtain a phenylboronic acid esterified prodrug with olefin double bonds; carrying out amidation reaction to obtain a tryptophan analogue coupling compound with olefin double bonds; the phenylboronic acid esterification prodrug, the tryptophan analogue coupling compound and other reactants are cross-linked to obtain hydrogel, and the hydrogel is post-treated to obtain the nanogel. The nanogel can be targeted to the L-type amino acid transporter 1 by virtue of the tryptophan analogue, cross a blood brain barrier and be enriched to an epilepsy focus; anti-epileptic drugs ...

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Номер записи: 3
22-06-2016 дата публикации

Multipurpose food fork

Номер: CN0205322180U
Автор: JIANG CHEN
Принадлежит:

... 本实用新型所述的多用途食品叉，本实用新型所述的多用途食品叉，包括手柄，所述手柄具有空腔结构，位于手柄顶端处分别向两侧延伸设置有固定叉齿，手柄的腔体中滑动套接有伸缩叉齿，所述伸缩叉齿头部位于手柄腔体之外，伸缩叉齿下端设置有锁定卡扣；所述手柄上活动穿设有汁液吸纳斗，所述汁液吸纳斗的收口处设置有固定带。本实用新型可在伸缩叉齿处于收缩状态时用作普通食品叉，将伸缩叉齿拉伸固定后可以作为烧烤叉棍使用，实现了一物多用，增加了生活便利性。在进行小块食物插取时，可在手柄上穿设一次性的汁液吸纳斗，并用汁液收纳斗收口处的固定带固定，非常方便卫生。本实用新型结构简单、使用方便、成本低廉，用途广泛。 ...

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Номер записи: 4
23-06-2023 дата публикации

Drug sustained release tablet and preparation method thereof

Номер: CN116270511A
Автор: QI NINGJIAO, QI JIANPING, WANG YUTING, JIANG CHEN, LIU YALIN
Принадлежит:

The invention discloses a drug sustained-release tablet and a preparation method thereof, the preparation method of the drug sustained-release tablet adopts powder direct compression or dry granulation for preparation, and the preparation process does not comprise a heating step; the drug sustained release tablet is prepared from the following raw materials: a lipid material, a hydrophobic lubricant and a high-solubility drug, wherein the lipid material comprises a waxy material, and the particle size D90 of the waxy material is less than 150 [mu] m; the raw materials do not contain a solvent. According to the invention, no extra solvent is introduced, heating is not needed, the qualified drug sustained-release tablet can be well prepared, the process is simple, the production efficiency is high, and active substances of drugs in the drug sustained-release tablet are stable.

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Номер записи: 5
04-08-2023 дата публикации

Warning system for expressway

Номер: CN116537094A
Автор: SUN XIAODAN, HAN XIAO, WANG DONG, TIAN YUBING, CAO XU, LI NA, JIANG CHEN, ZHANG HUI, SHAN RUI, WANG JIANKAI, WANG FANGLIANG
Принадлежит:

The invention discloses a warning system used on an expressway, and belongs to the field of Internet of Things. The problem that a tripod is placed on an existing highway to serve as a warning device, and the warning effect is poor is solved. The general control server stores the position information and the numbers of the m warning modules; the alarm module is further used for sending trigger signals to n trigger communication modules in an early warning area where an accident occurs after receiving the alarm, n is a positive integer and is smaller than m, and the number and the position of a scanned two-dimensional code are reported in a two-dimensional code scanning mode or the alarm is given in a telephone or video monitoring mode; each trigger communication module receives a trigger signal of the master control server and starts the corresponding warning module; after each warning module receives the starting signal, a warning signal is released in a warning lamp, sound and non-toxic ...

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Номер записи: 6
21-04-2023 дата публикации

Fluid distribution device and adsorption tower

Номер: CN115992010A
Автор: WANG DEYI, LI LIJUN, LAO GUORUI, HUANG BINGYAO, SUN FUWEI, LIU LINYANG, DAI JING, JIANG CHEN, XIE PING, HAO LEI
Принадлежит:

The invention provides a fluid distribution device and an adsorption tower, the fluid distribution device comprises at least two fluid distributors, each fluid distributor comprises an internal partition plate, an external partition plate and two radial side plates, and the internal partition plate and the external partition plate are respectively connected with the two radial side plates to form a cavity; a plurality of fluid distribution units are arranged in the cavity, and each fluid distribution unit comprises an upper-layer plate, a lower-layer plate, and an upper rotational flow assembly, a middle baffle and a lower flow stabilization assembly which are sequentially arranged between the upper-layer plate and the lower-layer plate from top to bottom; the rotational flow guide blades in the upper rotational flow assembly convert the flow pattern of the fluid into stable rotational flow through kinetic energy and static pressure energy of the fluid entering the fluid distributor, so ...

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Номер записи: 7
06-08-2020 дата публикации

VEHICLE ORIENTATION IDENTIFICATION METHOD AND APPARATUS

Номер: WO2020155998A1
Автор: JIANG, Chen
Принадлежит:

A vehicle orientation identification method and apparatus. The method comprises: acquiring multiple vehicle images of the same loss assessment case (21); performing vehicle orientation identification on each of the multiple vehicle images to acquire a vehicle orientation confidence vector of each image, wherein the vehicle orientation confidence vector of each image is used to represent the probability of a vehicle orientation in the vehicle image belonging to each vehicle orientation category (22); performing vehicle component identification on each of the multiple vehicle images to acquire a vehicle component test result of each image (23); and determining a vehicle orientation in a target vehicle image according to at least the vehicle orientation confidence vector of the target vehicle image and the vehicle component test result of the target vehicle image (24). Thereby, achieving a high efficiency in a vehicle orientation identification, and a high level of confidence in a result.

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Номер записи: 8
29-08-2023 дата публикации

Application of morusin in preparation of medicine for treating calcified aortic disease

Номер: CN116650470A
Автор: DONG NIANGUO, LIU ZONGTAO, WANG YIXUAN, LIU FAYUAN, CHEN YUQI, QIAO WEIHUA, XU LI, WANG KAN, JIANG CHEN
Принадлежит:

The invention belongs to the technical field of biological engineering, particularly discloses application of morusin in preparation of a medicine for treating calcified aortic diseases, and mainly relates to application of morusin in preparation of a medicine for preventing and treating aortic valve calcification. The invention also relates to application of morusin in inhibiting osteogenic differentiation of valvular interstitial cells in vitro for a non-diagnostic treatment purpose and application of morusin in preparing an osteogenic differentiation culture medium for a non-diagnostic treatment purpose. The effect of morusin in prevention and treatment of aortic valve calcification is defined, and a new means is provided for prevention and treatment of aortic valve calcification. Meanwhile, the application of morusin in osteogenic differentiation regulation of valvular interstitial cells and other non-diagnostic treatment purposes is also defined, and a new control means is provided ...

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Номер записи: 9
28-04-2023 дата публикации

Method and device for determining data similarity between sequence data

Номер: CN116030374A
Автор: JIANG CHEN, CHENG YUAN, ZHANG WEI
Принадлежит:

The embodiment of the invention provides a method and device for determining data similarity between sequence data. In the method for determining the data similarity between the sequence data, the data similarity between the sequence data is determined on the basis of data feature vectors of data elements of obtained to-be-queried sequence data and data feature vectors of data elements of reference sequence data in a reference sequence database. Selecting a first number of target reference sequence data from the reference sequence data; performing feature enhancement on the data feature vector of each data element of the to-be-queried sequence data and the data feature vector of each data element of each target reference sequence data, so that the data feature vector of each data element after feature enhancement is fused with local neighborhood information; and determining the similarity between the to-be-queried sequence data and each target reference sequence data according to the data ...

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Номер записи: 10
04-07-2023 дата публикации

Chemotherapeutic drug-polymer conjugate capable of triggering active transcellular transport as well as preparation method and application of chemotherapeutic drug-polymer conjugate

Номер: CN116370648A
Автор: JIANG CHEN, CHEN HONGYI, SUN TAO
Принадлежит:

The invention belongs to the technical field of medicines, and particularly relates to a chemotherapeutic drug-polymer conjugate capable of triggering an active transcellular transport effect as well as a preparation method and application thereof. The chemotherapeutic drug is a chemotherapeutic drug with an amino group or a hydroxyl group, and in the conjugate, the poly N-oxidized diethylaminoethyl methacrylate block can trigger an active cross-cell transport effect; the poly 2-(1-azacycloheptyl) ethyl methacrylate can respond to a slightly acidic environment in tumor tissues and can trigger STING monomer polymerization. The drug-loaded polymer nanoparticles prepared by encapsulating the small-molecule hydrophobic FAK inhibitor by the polymer conjugate have strong compatibility and good stability, and are suitable for selective delivery of various chemotherapeutic drugs and hydrophobic small-molecule inhibition; the drug delivery system has obvious tumor accumulation and tumor deep penetrating ...

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Номер записи: 11
11-07-2023 дата публикации

Application system management method and device, equipment, storage medium and product

Номер: CN116414539A
Автор: JIANG CHEN
Принадлежит:

The invention discloses a management method and device of an application system, equipment, a storage medium and a product, the application system is divided into a plurality of software and hardware units, and each software and hardware unit comprises application system software required by service capability, basic middleware providing a universal function and a hardware facility used for bearing the application system software. Therefore, each software and hardware unit can independently provide the corresponding service for the tenant. Based on this, according to the embodiment of the invention, the management of the application system can be completed according to the resource utilization rate calculated according to the resource information amount and the used resource amount, and the change of the resource utilization rate can adjust the unit or add the unit in the system, so that the upper limit problem of the service capability of each software and hardware facility is broken; ...

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Номер записи: 12
11-08-2023 дата публикации

Multi-mode anti-counterfeiting fluorescent powder and preparation method thereof

Номер: CN116574509A
Автор: ZHANG RUI, JIANG CHEN
Принадлежит:

The invention discloses a multi-mode anti-counterfeiting fluorescent powder, which has the characteristics of multi-mode excitation (the fluorescent powder presents white-in-green under the excitation of 254 nm and presents light pink under the excitation of 365 nm), dynamic luminescence (the luminescence color gradually changes from light pink to yellow green under the excitation of 265 nm) and afterglow luminescence (green). The general chemical formula of the fluorescent powder is xTb < 3 + >, yEu < 3 + >: Mg4-x-yGa4Ge3O16, x and y are molar fractions of corresponding elements, x is more than or equal to 0.01 and less than or equal to 0.02, and y is more than or equal to 0.02 and less than or equal to 0.04. The preparation process comprises the following steps: weighing oxides of all elements according to a stoichiometric ratio, grinding and uniformly mixing; putting the mixture into a muffle furnace, roasting for 2-4 hours at 800-1000 DEG C in an oxidizing atmosphere, naturally cooling ...

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Номер записи: 13
26-05-2023 дата публикации

Positioning and arranging equipment for spline to be subjected to cold extrusion

Номер: CN116159880A
Автор: WANG WEITAO, JIANG CHEN
Принадлежит:

The invention belongs to the technical field of feeding equipment, and particularly relates to positioning and arranging equipment for splines to be subjected to cold extrusion. Comprising a feeding device and a positioning and arranging device, and the feeding device is installed at the front end of the positioning and arranging device; the positioning arrangement device comprises a mounting frame, a positioning channel, a feeding channel, a positioning detection mechanism, a lifting mechanism, a horizontal conveying mechanism, a steering mechanism and a jacking tool, the positioning channel and the feeding channel are both arranged on the upper surface of the mounting frame in a penetrating mode, the positioning channel abuts against the feeding channel, and the front end of the positioning channel is connected with the feeding device; a first supporting frame, a second supporting frame and a jacking tool are arranged in the positioning channel from front to back at intervals. The direction ...

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Номер записи: 14
04-08-2023 дата публикации

Long-core multi-node flow experiment device and method

Номер: CN116539501A
Автор: LI NIANYIN, ZHU SHIJIE, FENG WENTAO, YU JIAJIE, JIANG CHEN, ZHANG HONG, WANG YUAN
Принадлежит:

The invention discloses a long core multi-node flow experiment device and method.The long core multi-node flow experiment device comprises an injection system, a confining pressure pump, a constant-temperature box, a long core holder, a computer, a sampling device, a six-way valve b and a six-way valve c, one end of the six-way valve b is connected with the injection system, the other end of the six-way valve b is connected with the long core holder, one end of the six-way valve c is connected with the long core holder, and the other end of the six-way valve c is connected with the computer. The other end of the six-way valve b is connected with a sampling device, the six-way valve b is also connected with the six-way valve c through a pipeline, and the long core holder is connected with a confining pressure pump; the long core holder is radially provided with a sampling port, one end of the sampling port is communicated with the interior of the long core holder, and the other end of the ...

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Номер записи: 15
27-08-2021 дата публикации

B column structure and automobile

Номер: CN214057711U
Автор: JIANG CHEN, MAO WEIZHONG, LU JIA, LI GUOFU, NIU SHENGFU, 蒋晨, 毛卫忠, 卢嘉, 李国富, 牛胜福
Принадлежит: SHANGHAI YUANCHENG AUTOMOBILE TECH CO LTD, SHANGHAI YUANCHENG AUTOMOBILE TECHNOLOGY CO., LTD., 上海元城汽车技术有限公司

The utility model discloses a B pillar structure and an automobile and belongs to the technical field of vehicles, the B pillar structure comprises an inner side plate, an outer side plate and a shielding assembly, the outer side plate is arranged on one side of the inner side plate, a cavity is formed between the inner side plate and the outer side plate, and foaming agents are filled in the cavity; the shielding assembly is connected to the inner side plate, and the shielding assembly can isolate functional holes and/or mounting nuts in the inner side plate in the cavity from the foaming agent; the automobile comprises the B column structure. The cavity is filled with the foaming agent, multi-scene machining can be achieved, the machining process effect can be well controlled, the shielding assembly is arranged on the inner side plate, the functional holes and the installation nuts are convenient to protect, the machining process is flexible, the bearing strength of the B column structure ...

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Номер записи: 16
26-05-2023 дата публикации

Novel semiconductor cooling clothes

Номер: CN116158578A
Автор: YU CHANGQING, JIANG CHEN, YOU ZHUHONG, XUE FURUI, YANG TIANTIAN, ZHANG SHANWEN, HWANG MOON-JOON, YU WENXUAN
Принадлежит:

The invention discloses a novel semiconductor cooling garment which comprises a cooling garment body, and a refrigerating system is connected to the cooling garment body. The cooling clothes body comprises two cooling clothes coats, the two cooling clothes coats are worn through a connecting assembly, the inner walls of the cooling clothes coats are fixedly connected with the cooling clothes body, cooling assemblies are arranged on the two cooling clothes body, and the top ends of the two cooling assemblies are communicated through a pipeline; the refrigerating system comprises a shell, a refrigerating assembly, a control assembly and a liquid storage assembly are arranged in the shell, the refrigerating assembly is fixedly communicated with the liquid storage assembly, the two cooling assemblies are fixedly communicated with the liquid storage assembly and the refrigerating assembly respectively, and the refrigerating assembly and the liquid storage assembly are arranged corresponding ...

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Номер записи: 17
26-05-2023 дата публикации

Polymer nanoparticles co-loaded with chemotherapeutic drug and small molecule inhibitor and preparation method thereof

Номер: CN116159150A
Автор: JIANG CHEN, CHEN HONGYI
Принадлежит:

The invention belongs to the field of pharmaceutical preparations, and relates to polymer nanoparticles co-loaded with chemotherapeutic drugs and small-molecule inhibitors and a preparation method of the polymer nanoparticles. In particular to a nano-particle co-loaded with phosphorylated gemcitabine and HJC0152 for deep penetration of pancreatic cancer and regulation of tumor microenvironment. The nano-particle is a nano-drug delivery system prepared from phosphorylated gemcitabine, HJC0152, a hypoxia sensitive cross-linking agent, a dendritic polylysine monomer, a nucleic acid aptamer GBI-10, an injection solvent and the like. The nanoparticles are loaded with drugs through electrostatic adsorption and chemical coupling respectively, the stability is good, the preparation process is simple and feasible, and the particle size distribution is uniform. The compound can stably exist in systemic circulation, realizes specific charge correction, particle size reduction and drug release at a ...

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Номер записи: 18
30-06-2023 дата публикации

Drug delivery system for regulating and controlling tumor immunosuppression microenvironment and reversing drug resistance

Номер: CN116350793A
Автор: SUN TAO, JIANG CHEN
Принадлежит:

The invention belongs to the technical field of biology, and relates to a drug delivery system, in particular to a drug delivery system for regulating and controlling a tumor immunosuppression microenvironment and reversing drug resistance. The drug delivery system is prepared by taking a polyethylene glycol-polylysine-polyphenylalanine (PEG-Ply-Pphe) triblock polymer as a construction element, and can respond to a tumor slightly acidic microenvironment, the surface charge is changed from negative to positive, and penetration can be increased; the two loaded prodrugs can further release drugs in a tumor microenvironment, and can regulate and control a tumor immune microenvironment and reverse tumor drug resistance by inhibiting STAT3 (Signal Transducer and Activator of Transcription 3) respectively. The method disclosed by the invention is expected to play an enlightenment role in the field of clinical conversion of nano-drugs.

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Номер записи: 19
21-04-2023 дата публикации

Layered collaborative optimization method and system for power distribution network

Номер: CN115995821A
Автор: ZHANG TAO, ZHENG LI, LIU ZHUGUANG, WANG XIAOFANG, CHEN MENGXIAN, JIANG CHEN, DAI WENBO, MA JUNHUA, NOBUHOSHI, TIAN HAO
Принадлежит:

The invention discloses a hierarchical collaborative optimization method and system for a power distribution network. Comprising the steps of obtaining output prediction data of renewable energy in an area where a power distribution network is located through energy resource condition analysis; taking the minimum annual cost of an energy system of the power distribution network as an objective function target, and establishing a multi-source collaborative aggregation model containing multiple loads; according to the output prediction data, a piecewise linearization and convex-concave process optimization method is adopted to optimize sub-problems in the multi-source collaborative aggregation model, and a multi-source collaborative aggregation optimization model is obtained; and solving the multi-source collaborative aggregation optimization model by adopting a mixed integer scale method to obtain a hierarchical collaborative optimization result of the power distribution network. The hierarchical ...

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Номер записи: 20
01-08-2023 дата публикации

Hypoxia response drug delivery micelle adaptive to pancreatic cancer microenvironment and preparation method of hypoxia response drug delivery micelle

Номер: CN116509801A
Автор: SUN TAO, LUO YIFAN, JIANG CHEN
Принадлежит:

The invention belongs to the technical field of nano drug loading, and particularly relates to a hypoxia response drug delivery micelle adaptive to a pancreatic cancer microenvironment and a preparation method. The hypoxia response polymer is polyethylene glycol-polylysine-paclitaxel-polyphenylalanine, a polyethylene glycol-polylysine-polyphenylalanine triblock polymer is formed through a ring-opening polymerization reaction, then amino on lysine of the triblock polymer and a disulfide bond are coupled with a chemotherapeutic drug paclitaxel, and the hypoxia response polymer is obtained. Then connecting an azide group at the tail end of polyethylene glycol with alkynyl at the tail end of polypeptide CREKA or Ni-Alk through a click chemical reaction, and wrapping a gemcitabine prodrug in a core of the nano response micelle through physical encapsulation. The nano drug delivery micelle can respond to a tumor microenvironment to release chemotherapeutic drugs gemcitabine and paclitaxel, and ...

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Номер записи: 21
30-06-2023 дата публикации

Hybrid hysteresis control system

Номер: CN116365839A
Автор: JIANG CHEN, CHOUDHURY SUJIT, AKUNDI SUBHASH BALKRISHNA
Принадлежит:

The invention discloses a hybrid hysteresis control system. A system includes a first comparator (260A), a second comparator (260B), a pulse width modulation (PWM) controller (270), and a ramp generator (285). The first comparator has a positive input coupled to a first ramp output (290A) of the ramp generator and a negative input configured to receive an input voltage (155). The second comparator has a positive input configured to receive the input voltage and a negative input coupled to a second ramp output (290B) of the ramp generator. A PWM controller is coupled to the outputs of the first and second comparators and a control signal input, and has a control output. In some embodiments, a ramp generator generates a high-side descent ramp for a first comparator and generates a low-side ascent ramp for a second comparator. In some embodiments, the ramp generators include a first ramp generator for a high-side descending ramp and a second ramp generator for a low-side ascending ramp.

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Номер записи: 22