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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Применить Всего найдено 13. Отображено 13.
24-01-2019 дата публикации

분자량분포 특성을 조절한 이토프라이드 염산염 함유 서방제제

Номер: KR0101941511B1
Автор: 최연웅, 민병구, 조상민, 기도형, 최은정, 조아라, 조문경
Принадлежит: 한국유나이티드제약 주식회사

... 본 발명에 따른 이토프라이드 염산염 함유 서방성 이층정제는 용출제어 특성이 매우 우수하여, 구강 투여 초기부터 장시간 동안 용출이 일정하게 안정적으로 유지됨으로써, 투여 후 혈중 유효성분 농도의 급격한 상승에 따라 두통, 현기증, 복통 등을 느끼기 쉬운 민감성 체질의 환자에게 적합하다.

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Номер записи: 1
20-06-2016 дата публикации

Solid preparations containing choline alfoscerate and preparing method thereof

Номер: KR0101631846B1
Автор: 최연웅, 민병구, 기도형, 전형준, 최은정, 조상민, 하대철, 박희찬, 송희용
Принадлежит: 한국유나이티드제약 주식회사

... 본 발명은 규산칼슘이 콜린알포세레이트를 흡착함으로써 고체 형태의 제형화가 가능하도록 한, 콜린알포세레이트 및 규산칼슘을 포함하는 고형 제제 및 이의 제조 방법에 대한 것이다. 본 발명의 콜린알포세레이트 및 규산칼슘을 포함하는 고형 제제의 경우, 연질캡슐 제형에 비하여 미생물에 의해 변질되거나, 습기에 의해 안정성이 저하될 염려가 적고, 부피가 작아 복용 편의성이 우수한 장점이 있다. 또한, 본 발명은 붕해제를 2 이상 혼합하여 사용하여 고형 제제의 초기 용출률을 향상시킴으로써, 기존의 연질캡슐 제형과 동등한 수준의 용출 프로파일을 나타내므로 약효의 발현 면에서 차이가 없다.

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Номер записи: 2
24-07-2018 дата публикации

방출제어형 경질캡슐 제제

Номер: KR0101869406B1
Автор: 최연웅, 조상민, 장재상, 이남송, 기도형, 김보경
Принадлежит: 한국유나이티드제약 주식회사

... 본 발명은 방출제어형 경질캡슐 제제에 관한 것으로, 구체적으로 제1 약물 또는 그의 약학적으로 허용되는 염 및 속효성 부형제를 포함하는 속방부; 및 제2 약물 또는 그의 약학적으로 허용되는 염 및 방출제어용 고분자를 포함하는 서방부를 포함하는 것인 경질캡슐 제제에 관한 것이다.

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Номер записи: 3
31-10-2019 дата публикации

ENTERIC COATED TABLET COMPRISING FENOFIBRIC ACID OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF

Номер: WO2019208967A1
Автор: CHOI, Youn Woong, CHO, Sang Min, KI, Do Hyoung, SONG, In Ho
Принадлежит:

The present invention relates to an enteric coated tablet comprising fenofibric acid or a pharmaceutically acceptable salt thereof and to a manufacturing method therefor. The present invention can minimize the loss of a drug and increase the solubility of the drug, thereby maximizing bioavailability with even a small amount of the drug.

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Номер записи: 4
18-01-2016 дата публикации

SOLID PREPARATION CONTAINING CHOLINE ALFOSCERATE AND PREPARING METHOD THEREOF

Номер: KR1020160005971A
Автор: CHOI, YOUN WOONG, MIN, BYUNG GU, KI, DO HYOUNG, JUN, HYUNG JOON, CHOI, EUN JUNG, CHO, SANG MIN, HA, DAE CHUL, PARK, HEE CHAN, SONG, HEE YONG
Принадлежит:

The present invention relates to a solid preparation comprising choline alfoscerate and calcium silicate by calcium silicate adsorbing choline alfoscerate, and to a manufacturing method thereof. The solid preparation comprising choline alfoscerate and calcium silicate has has less possibilities of being spoiled by microorganisms or having stability reduced by moisture, and has small volume to have excellent administration convenience compared with a soft capsule preparation. The solid preparation comprising choline alfoscerate and calcium silicate of the present invention uses two or more mixed disintegrating agents to improve initial elution rate to have an elution profile having the level same to an existing soft capsule preparation, thereby not having difference in an aspect of expression of a drug effect. COPYRIGHT KIPO 2016 ...

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Номер записи: 5
07-03-2013 дата публикации

CONTROLLED-RELEASE ORAL COMPOSITION CONTAINING ITOPRIDE HYDROCHLORIDE, AND PREPARATION METHOD THEREOF

Номер: WO2013032206A1
Автор: CHOI, Yeon Ung, MIN, Byeong Gu, CHO, Sang Min, KI, Do Hyoung, PARK, Yeong Min
Принадлежит:

The present invention relates to a preparation method of an extended release tablet containing itopride hydrochloride as an active ingredient, and more specifically, the present invention provides an extended release tablet in which dissolution is extended for enabling administration of one dose per day, thereby improving administration convenience and compliance when compared to existing commercial preparations which are taken three times a day. The itopride extended release tablet according to the present invention can effectively control the release of itopride hydrochloride with a velocity close to zero order for 24 hours without the deviation of dissolution, and thus the inconvenience of taking three doses per day can be solved by taking only one dose per day. In addition, since the weight per tablet is 450 mg and the size of a tablet is small, the compliance of a patient is high, thereby preventing the loss of efficacy or the worsening of symptoms.

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Номер записи: 6
30-05-2013 дата публикации

CHEWABLE SILDENAFIL CITRATE TABLETS IN WHICH BITTERNESS IS MASKED, AND PRODUCTION METHOD THEREFOR

Номер: WO2013077533A1
Автор: CHOI, Yeon Ung, MIN, Byeong Gu, CHO, Sang Min, KI, Do Hyoung, LEE, Byung Hoon
Принадлежит:

The present invention relates to a method for producing chewable tablets of sildenafil citrate, a therapeutic agent for erectile dysfunction, in which the bitterness of the sildenafil citrate is masked and which are easy to take, and the invention provides chewable sildenafil citrate tablets in which the bitterness is masked by the use of an ion-exchange resin having a carboxyl group. The chewable sildenafil citrate salt tablets produced in accordance with the present invention are outstanding in terms of rapidity of elution and concealment of bitterness, and are easy to take and can therefore be expected to be very useful when administered to patients.

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Номер записи: 7
10-05-2016 дата публикации

ANTITUSSIVE AND EXPECTORANT COMPOSITION, COMPRISING MIXED EXTRACT OF RHIZOMA COPTIDIS AND PELARGONIUM SIDOIDES

Номер: KR1020160050006A
Автор: CHOI, YOUN WOONG, MIN, BYUNG GU, HA, DAE CHUL, CHO, SANG MIN, SONG, HEE YONG, PARK, HEE CHAN, KI, DO HYOUNG, JUNG, WON TAE, NAM, KYU YEOL
Принадлежит:

The present invention relates to a usage of a mixed extract of Rhizoma Coptidis and Pelargonium sidoides as an antitussive and expectorant composition, and to a usage of preventing or treating respiratory diseases or respiratory infections. COPYRIGHT KIPO 2016 ...

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Номер записи: 8
14-01-2016 дата публикации

SOLID PREPARATION COMPRISING CHOLINE ALFOSCERATE AND METHOD FOR PREPARING SAME

Номер: WO2016006862A1
Автор: CHOI, Youn Woong, MIN, Byung Gu, KI, Do Hyoung, JUN, Hyung Joon, CHOI, Eun-Jung, CHO, Sang Min, HA, Dae-Chul, PARK, Hee-Chan, SONG, Hee-Yong
Принадлежит:

The present invention relates to a solid preparation comprising choline alfoscerate and calcium silicate and a method for preparing the same, wherein calcium silicate adsorbs choline alfoscerate and thereby enables formulation in a solid form. Compared to soft capsule formulations, the solid preparation of the present invention, comprising choline alfoscerate and calcium silicate, has advantages of there being less concern regarding deterioration due to microorganisms and stability degradation due to moisture, and of being excellent in the ease of dosing because of a smaller volume. In addition, the present invention improves the initial dissolution rate of the solid preparation by using two or more disintegrants by mixture and thereby exhibits the same level of dissolution profile as conventional soft capsule formulations, and therefore is not different therefrom in the expression of a medicinal effect.

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Номер записи: 9
06-05-2016 дата публикации

ANTITUSSIVE AND EXPECTORANT COMPOSITION CONTAINING, AS ACTIVE INGREDIENT, MIXTURE EXTRACT OF COPTIDIS RHIZOME AND PELARGONIUM SIDOIDES

Номер: WO2016068607A1
Автор: CHOI, Youn Woong, MIN, Byung Gu, HA, Dae Chul, CHO, Sang Min, SONG, Hee Yong, PARK, Hee Chan, KI, Do Hyoung, JUNG, Won Tae, NAM, Kyu Yeol
Принадлежит:

The present invention relates to a use of a mixture extract of Coptidis rhizome and Pelargonium Sidoides as anantitussive or expectorant agent, and a use of the same for preventing or treating respiratory diseases or respiratory infection.

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Номер записи: 10
05-06-2017 дата публикации

CONTROLLED RELEASE-TYPE HARD CAPSULE PREPARATION

Номер: KR1020170061219A
Автор: CHOI, YUN WOONG, CHO, SANG MIN, JANG, JAE SANG, LEE, NAM SONG, KI, DO HYOUNG, KIM, BO KYUNG
Принадлежит:

The present invention relates to a controlled release-type hard capsule preparation. More specifically, the present invention relates to a hard capsule preparation which comprises: a quick-release part containing a first drug or a pharmaceutically acceptable salt thereof and a fast-acting diluting agent; and a slow-release part containing a second drug or a pharmaceutically acceptable salt thereof and a polymer for release control. COPYRIGHT KIPO 2017 (AA) Pellet (Slow-release part) (BB) Granule (Quick-release part) ...

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Номер записи: 11
20-08-2020 дата публикации

METHOD FOR PREPARATION OF LEVODROPROPIZINE-CONTAINING, SUSTAINED-RELEASE TABLET

Номер: WO2020166835A1
Автор: CHOI, Youn Woong, CHO, Sang Min, KI, Do Hyoung, KIM, Bo Kyung
Принадлежит:

The present invention relates to a method for preparation of a levodropropizine-containing, sustained-release tablet composed of a sustained release layer responsible for delayed release, and an immediate release layer, each layer containing levodropropizine. When prepared by the method of the present invention, the levodropropizine-containing, sustained-release tablet is superb in terms of dissolution as well as formulation characteristics such as friability, hardness, preparation uniformity, and so on and thus exhibits excellent stability during long-term storage and transport.

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Номер записи: 12
25-08-2017 дата публикации

황련 및 펠라고니움 시도이데스 혼합 추출물을 유효성분으로 포함하는, 진해 거담용 조성물

Номер: KR0101770606B1
Автор: 최연웅, 민병구, 하대철, 조상민, 송희용, 박희찬, 기도형, 정원태, 남규열
Принадлежит: 한국유나이티드제약 주식회사

... 본 발명은 황련(Coptidis rhizome) 및 펠라고니움 시도이데스(Pelargonium Sidoides) 혼합 추출물의 진해 또는 거담제로서의 용도 및 호흡기 질환 또는 기도 감염의 예방 또는 치료 용도에 관한 것이다.

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Номер записи: 13