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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 58. Отображено 58.
04-07-2017 дата публикации

연속적인 데이터 수집 및 적재 방법, 그리고 그 방법을 위한 시스템

Номер: KR0101753897B1
Автор: 송희용
Принадлежит: 주식회사 이롬테크놀로지

... 연속적인 데이터 수집 및 적재 방법, 그리고 그 방법을 위한 시스템이 개시된다. 이 방법의 제1 단계에서, 상기 복수의 데이터 소스에 대해 정의되어 있는 입력 플러그인이 상기 정의에 따라 상기 복수의 데이터 소스에 대한 탐지 동작을 수행한다. 제2 단계에서, 상기 입력 플러그인에 의한 탐지 동작 결과 상기 복수의 데이터 소스의 현황에 따라 에이전트 플러그인이 상기 복수의 데이터 소스 내부의 실제 데이터를 탐지한다. 제3 단계에서, 상기 에이전트 플러그인의 탐지 결과에 따라 서브에이전트 플러그인이 상기 복수의 데이터 소스로부터 데이터를 읽어 들이면서 데이터에 대한 처리를 수행한다. 제4 단계에서, 출력 플러그인이 상기 서브에이전트 플러그인에 의해 처리된 데이터들을 압축한 후 저장 포맷으로 변환하여 저장 시스템에 저장한다.

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Номер записи: 1
03-01-2019 дата публикации

용출 특성을 조절한 모사프리드 함유 경구 투여 서방제제

Номер: KR1020190000660A
Автор: 김병진, 송희용, 최연웅, 하대철, 권인호, 김용희
Принадлежит:

... 본 발명의 모사프리드 또는 이의 염을 함유하는 경구투여 서방성 이층정제는 신속한 약리활성 발현과 24시간 동안 약리 활성의 지속을 동시에 충족시키기 위하여, 약물을 신속하게 용출되도록 하는 속방층과 서서히 용출되도록 하는 서방층으로 이루어진 서방성 이층정제로서, 최적의 용출 양상을 나타내기 위하여, 점도가 상이한 3종의 히드록시프로필메칠셀룰로오스를 혼합하여 방출조절제로 사용하였으며, pH가 상이한 각 위장관 내 부위에서의 용출율 및 위장관에서의 체류시간을 제어하는 것이 특징이다. 또한, 본 발명은 환자의 복약 순응도를 높이면서, 상기한 바와 같은 우수한 효과를 보이는 모사프리드 함유 경구투여 서방성 이층정제의 제조 방법을 제공한다.

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Номер записи: 2
06-07-2015 дата публикации

SUSTAINED-RELEASE MATRIX FORMULATION COMPRISING MOSAPRIDE IN MATRIX AND COATING LAYER FOR TREATING DISEASE AND MANUFACTURING METHOD THEREOF

Номер: KR1020150075956A
Автор: KIM, BYUNG JIN, CHOI, YOUN WOONG, SONG, HEE YONG, KIM, JONG IL, KIM, YONG HEE, LIM, MYOUNG HWA, KIM, MIN SOO, HA, DAE CHUL
Принадлежит:

The present invention relates to a manufacturing method of a sustained-release matrix formulation comprising mosapride for oral administration, which represents effects in alleviating gastrointestinal disease. The present invention has the structure of a sustained release matrix formulation comprising mosapride with a coating layer containing an active ingredient and a coating agent on the surface of a matrix formulation comprising an active ingredient, filler, a disintegrating agent, a sustained release agent, and an additive, in comparison with the conventional method of a sustained-release matrix formulation. A matrix of the present invention comprises an active ingredient and various additives, wherein a coating layer and a matrix represent effects of a rapid release layer and a sustained release layer, respectively. COPYRIGHT KIPO 2015 (BB) Matrix comprising active ingredients (AA) Coating layer comprising active ingredients ...

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Номер записи: 3
20-06-2016 дата публикации

Solid preparations containing choline alfoscerate and preparing method thereof

Номер: KR0101631846B1
Автор: 최연웅, 민병구, 기도형, 전형준, 최은정, 조상민, 하대철, 박희찬, 송희용
Принадлежит: 한국유나이티드제약 주식회사

... 본 발명은 규산칼슘이 콜린알포세레이트를 흡착함으로써 고체 형태의 제형화가 가능하도록 한, 콜린알포세레이트 및 규산칼슘을 포함하는 고형 제제 및 이의 제조 방법에 대한 것이다. 본 발명의 콜린알포세레이트 및 규산칼슘을 포함하는 고형 제제의 경우, 연질캡슐 제형에 비하여 미생물에 의해 변질되거나, 습기에 의해 안정성이 저하될 염려가 적고, 부피가 작아 복용 편의성이 우수한 장점이 있다. 또한, 본 발명은 붕해제를 2 이상 혼합하여 사용하여 고형 제제의 초기 용출률을 향상시킴으로써, 기존의 연질캡슐 제형과 동등한 수준의 용출 프로파일을 나타내므로 약효의 발현 면에서 차이가 없다.

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Номер записи: 4
21-09-2017 дата публикации

COMPOSITE PREPARATION CONTAINING CLOPIDOGREL AND ASPIRIN

Номер: WO2017160101A1
Автор: CHOI, Yun Woong, HA, Dae Chul, SONG, Hee Yong, KWON, In Ho, JUNG, Rae Hoon, YANG, Seung Jin, YU, Keoun Hui, WI, Tae In
Принадлежит:

The present invention relates to a composite preparation containing clopidogrel and aspirin and to a method for preparing the same, wherein the composite preparation has stability maintained even during storage and distribution and shows a fast clopidogrel tablet disintegration rate.

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Номер записи: 5
04-01-2017 дата публикации

SUSTAINED RELEASE MOSAPRIDE PREPARATION AND COMPOSITE PREPARATION OF MOSAPRIDE AND RABEPRAZOLE

Номер: KR1020170001545A
Автор: KIM, BYUNG JIN, CHOI, YOUN WOONG, SONG, HEE YONG, KIM, JONG IL, KIM, YONG HEE, LIM, MYOUNG HWA, KIM, MIN SOO, HA, DAE CHUL
Принадлежит:

The present invention relates to a sustained release preparation which contains small-sized mosapride having the total weight less than or equal to 200 mg, and is orally taken once a day. The present invention further relates to a composite preparation of mosapride and rabeprazole. According to the present invention, the sustained release preparation releases drugs by controlling the elution rate. COPYRIGHT KIPO 2017 (AA) Mosapride citrate preparation 5mg (BB) Example 3 (Hunger) (CC) Example 3 (After meals) ...

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Номер записи: 6
29-12-2015 дата публикации

An orally administered drug, comprising extract of coptidis rhizome with bitter taste thereof masked

Номер: KR0101580119B1
Автор: 최연웅, 민병구, 하대철, 조상민, 송희용, 박희찬, 안지현
Принадлежит: 한국유나이티드제약 주식회사

... 본 발명은 황련(Coptidis rhizome) 추출물 및 설폰산 기를 가지는 양이온교환수지를 포함하는, 쓴맛이 차폐된 경구투여용 제제 및 이의 제조 방법에 관한 것이다.

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Номер записи: 7
03-01-2019 дата публикации

1일 1회 경구투여하는 모사프리드 함유 서방제제

Номер: KR1020190000658A
Автор: 김병진, 송희용, 최연웅, 하대철, 권인호, 김용희
Принадлежит:

... 본 발명의 모사프리드 또는 이의 염을 함유하는 경구투여 서방성 이층정제는 신속한 약리활성 발현과 24시간 동안 약리 활성의 지속을 동시에 충족시키기 위하여, 약물을 신속하게 용출되도록 하는 속방층과 서서히 용출되도록 하는 서방층으로 이루어진 서방성 이층정제로서, 최적의 용출 양상을 나타내기 위하여, 치환도에 따라 용출 특성이 상이한 수 종의 용출 제어 기제를 방출조절제로 사용하며, pH가 상이한 각 위장관 내 부위에서의 용출률 및 위장관에서의 체류시간을 제어하는 것이 특징이다. 또한, 본 발명은 환자의 복약 순응도를 높이면서, 초기 유효성분의 과다방출로 인한 부작용을 방지하도록 고안된 모사프리드 함유 경구투여 서방성 이층정제의 제조 방법을 제공한다.

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Номер записи: 8
20-09-2017 дата публикации

ORAL PHARMACEUTICAL COMPOSITION COMPRISING (±)-2-[2-(3-CARBOXYPROPIONYLOXY)-3-DIMETHYLAMINOPROPOXY]-3′-METHOXYBIBENZYL OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF

Номер: KR1020170106126A
Автор: CHOI, YOUN WOONG, HA, DAE CHUL, KWON, IN HO, KIM, AH YOUNG, SONG, HEE YONG, JUNG, RAE HOON, CHOI, BO RAM
Принадлежит:

One embodiment of the present invention provides a pharmaceutical composition for alleviating or treating ischemic symptoms of chronic total occlusion, which comprises (±)-2-[2-(3-carboxypropionyloxy)-3-dimethylaminopropoxy]-3′-methoxybibenzyl hydrochloride as an effective component. COPYRIGHT KIPO 2017 (AA) Dissolution rate (%) (BB) Time (hr) (CC) Example 11 (DD) Example 12 ...

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Номер записи: 9
13-05-2016 дата публикации

Mosapride citrate sustained-release matrix formulation dispersed by pellet, and preparing the method thereof

Номер: KR0101620856B1
Автор: 김병진, 최연웅, 송희용, 김종일, 김용희, 임명화, 김민수, 하대철
Принадлежит: 한국유나이티드제약 주식회사

... 본 발명의 모사프리드 구연산염을 포함하는 캡슐 제제의 경우, 부정맥 및 심인성 급사의 우려가 없고, 중추신경계 부작용, 고프롤락틴혈증 등의 부작용이 없어 안전하게 사용할 수 있다. 또한 종래의 서방형 매트릭스 제제에 비하여 용출시간 조절이 비교적 정확하게 제어가 가능하고, 그 용출패턴이 Zero-order와 유사한 패턴을 보인다는 장점이 있다.

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Номер записи: 10
04-01-2017 дата публикации

COMPOSITE PREPARATION OF MOSAPRIDE AND RABEPRAZOLE

Номер: KR1020170001664A
Автор: CHOI, YOUN WOONG, SONG, HEE YONG, HA, DAE CHUL, KIM, BYUNG JIN, YIE, UN HAE
Принадлежит:

The present invention relates to a composite preparation of mosapride and rabeprazole, having various formulations. The composite preparation produced by the present invention enables immediate drug release without reduction in the elution rate due to interactions between mosapride and rabeprazole, thereby exhibiting increased drug elution rate and bioavailability. In addition, the composite preparation of mosapride and rabeprazole shows product stability, and remarkably reduces an amount of diluting agents used therein, thereby increasing administration compliance in patients due to the size of the formulations. COPYRIGHT KIPO 2017 (A1,A2) Rabeprazole tablet for intestinal coating (BB) Mosapride granule (CC) Mosapride double tablet comprising Rabeprazole dry coated tablet (DD) Quick-release layer (EE) Slow-release layer (FF) Mosapride double tablet ...

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Номер записи: 11
17-03-2016 дата публикации

오메가-3 지방산 에스테르 및 스타틴계 약물을 포함하는 경구용 복합제제

Номер: KR1020160030383A
Автор: 최연웅, 민병구, 하대철, 조상민, 송희용, 박희찬, 권인호, 김아영, 양승진
Принадлежит:

... 본 발명은 오메가-3 지방산 에스테르 및 스타틴 계열 약물을 포함하는 약제학적 복합제제에 관한 것이다. 본 발명에 따른 경구용 복합제제는 오메가-3 지방산 에스테르를 포함하는 캡슐제 내부에, 스타틴 계열 약물이 포함된 정제를 함입하고 있으므로 원천적으로 수분, 낮은 pH 등 외부 환경과의 접촉이 완전히 차단되며, 높은 안정성과 우수한 붕해율 및 용출율을 보이는 장점이 있다.

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Номер записи: 12
30-10-2018 дата публикации

FLAME-RETARDANT INSULATIVE FINISHING MATERIAL COMPOSITION, MANUFACTURING METHOD THEREOF AND CONSTRUCTION METHOD USING SAME

Номер: KR101913388B1
Автор: LEE CHANG MOOK, SONG, HEE YONG
Принадлежит: HONGSUNGENG CO., LTD., SESCERAMIC CO., LTD.

The present invention relates to a flame-retardant insulative finishing material composition, a manufacturing method thereof and a construction method using the same. More specifically, the flame-retardant insulative finishing material composition comprises 5-30 wt% of Styrofoam powder, 3-20 wt% of calcium carbonate, 10-40 wt% of white cement, 15-45 wt% of calcium aluminate, 3-30 wt% of a hollow filler, 1-15 wt% of cellulose fiber, 0.5- 15 wt% of aliphatic metal salt, 1-5 wt% of an air entraining agent, 0.1-5 wt% of cellulose ether, 0.01-3 wt% of a curing accelerator, and 0.01-3 wt% of a curing aid. According to the present invention, the flame-retardant insulative finishing material composition has excellent flame retardance and insulation, has excellent compressive strength, bonding strength, and impact resistance without eluting harmful materials, and facilitates spraying and wall coating simply by adding water at a work site. COPYRIGHT KIPO 2018 ...

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Номер записи: 13
23-07-2015 дата публикации

PORTABLE DEVICE AND CONTROL METHOD USING PLURALITY OF CAMERAS

Номер: WO2015108401A1
Автор: LEE, Jongwoo, MOON, Hyejin, SONG, Heeyong
Принадлежит:

A method for controlling a terminal including a camera according to an embodiment of the present specification comprises the steps of: receiving an image through the camera; determining at least one object from the received image; calculating the distance between the object and the terminal on the basis of information related to the determined object; and outputting a signal determined on the basis of the distance between the calculated object and the terminal. According to an embodiment of the present specification, information between the terminal and a neighboring object can be determined on the basis of image information which a plurality of visual input devices has received, and an auditory output can be provided on the basis of the determined information. Further, the method has identification methods and identifiable distances different according to a distance from a neighboring object, and thus can provide information on neighboring objects different according to a motion pattern ...

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Номер записи: 14
08-12-2016 дата публикации

PHARMACEUTICAL COMPLEX PREPARATION

Номер: KR1020160141314A
Автор: CHOI, YOUN WOONG, MIN, BYUNG GU, HA, DEA CHUL, CHO, SANG MIN, SONG, HEE YONG, PARK, HEE CHAN, JANG, JAE SANG, KWON, IN HO, KIM, AH YOUNG, YANG, SEUNG JIN, YU, KEOUN HUI
Принадлежит:

The present invention relates to a pharmaceutical complex preparation comprising clopidogrel and aspirin. In the complex preparation, granules having a clopidogrel layer coated with a fast-release protecting layer and asprin granules having an aspirin layer coated with an enteric coating layer are encapsulated. According to the present invention, a physical contact between clopidogrel and aspirin is interrupted to prevent an eutectic phenomenon fundamentally. Thus, it is possible to prevent a change in the contents, dissolution characteristics and bio-equivalence of the preparation in the short run, and to improve the stability of the preparation in the long run. It is also possible to prevent a damage of the stomach wall by coating aspirin with an enteric coating layer. In addition, a moisture-proof layer is used to improve the stability of water-sensitive clopidogrel and a salt thereof to minimize production of clopidogrel impurities without any change in dissolution amount of clopidogrel ...

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Номер записи: 15
03-01-2019 дата публикации

분자량분포 특성을 조절한 모사프리드 함유 서방제제

Номер: KR1020190000657A
Автор: 김병진, 송희용, 최연웅, 하대철, 권인호, 김용희
Принадлежит:

... 본 발명에 따른 모사프리드시트르산 함유 서방성 이층정제는 용출제어 특성이 매우 우수하여, 구강 투여 초기부터 장시간 동안 용출이 일정하게 안정적으로 유지됨으로써, 투여 후 혈중 유효성분 농도의 급격한 상승에 따라 쉽게 구토나 어지러움을 느끼는 체질의 민감성 환자에게 적합하다.

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Номер записи: 16
14-11-2019 дата публикации

QUASI-NONFLAMMABLE FINISHING MATERIAL COMPOSITION, PREPARATION METHOD OF SAME, AND CONSTRUCTION METHOD USING SAME

Номер: WO2019216518A1
Автор: LEE, Chang Mook, SONG, Hee Yong
Принадлежит:

The present invention relates to a quasi-nonflammable finishing material composition, a preparation method of same, and a construction method using same. More specifically, the present invention relates to a quasi-non flammable finishing material composition comprising 5-30 wt% of shredded Styrofoam , 3-20 wt% of calcium carbonate, 10-40 wt% of white cement, 15-45 wt% of calcium aluminates, 3-30 wt% of a hollow body filler, 1-15 wt% of cellulose fibers, 0.5-15 wt% of fatty acid metal salts, 1-5 wt% of an air-entraining admixture, 0.1-5 wt% of cellulose ether, 0.01-3 wt% of a curing accelerator , and 0.01-3 wt% of a curing coagent; a preparation method of same; and a construction method using same. According to the present invention, there is an effect of providing a quasi-nonflammable finishing material composition which not only has desirable flame retardancy and thermal insulation properties, but also has desirable compressive strength, adhesive strength, and impact resistance without ...

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Номер записи: 17
20-06-2019 дата публикации

CORE TABLET COMPOSITE PREPARATION COMPRISING MOSAPRIDE AND RABEPRAZOLE

Номер: WO2019117502A1
Автор: KIM, Byung Jin, SONG, Hee Yong, CHOI, Youn Woong, KIM, Seong Yeob
Принадлежит:

The present invention relates to a composite preparation in a core tablet form, composed of an inner core containing rabeprazole as an effective ingredient; an outer layer portion including the bilayer structure of a sustained release layer and an immediate release layer and containing mosapride as an effective ingredient. The core tablet composite preparation according to the present invention is characterized by exerting sufficient pharmacological activity of rabeprazole and mosapride even upon administration of one tablet once a day.

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Номер записи: 18
19-07-2017 дата публикации

FINISHING MATERIAL COMPOSITION HAVING EXCELLENT THERMAL INSULATION AND FLAME RETARDANCY, AND SPRAYING CONSTRUCTION METHOD USING SAME

Номер: KR101759448B1
Автор: LEE, CHANG MOOK, SONG, HEE YONG
Принадлежит: HONGSUNGENG CO., LTD., SONG, HEE YONG

The present invention relates to a finishing material composition having excellent thermal insulation and flame retardancy, and a spraying construction method using the finishing material composition. More specifically, the present invention relates to a finishing material composition having excellent thermal insulation and flame retardancy, the finishing material composition comprising a) 20 to 40 wt% (based on the solid content) of an aqueous polyurethane resin dispersion, b) 10 to 20 wt% of aluminum hydroxide, c) 10 to 20 wt% of magnesium hydroxide, d) 5 to 15 wt% of talc, e) 10 to 20 wt% of Styrofoam crushed powder, f) 5 to 15 wt% of a thickener, and g) 1 to 10 wt% of an antifoaming agent, and a spraying construction method using the finishing material composition. The present invention has an effect of providing a finishing material composition which not only is excellent in thermal insulation and flame retardancy, but also is excellent in dew condensation prevention, sound absorption ...

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Номер записи: 19
06-07-2015 дата публикации

SUSTAINED-RELEASE CAPSULE FORMULATION COMPRISING MOSAPRIDE CITRATE MINI-TABLETS FOR TREATING GASTROINTESTINAL DISEASE AND MANUFACTURING METHOD THEREOF

Номер: KR1020150075959A
Автор: KIM, BYUNG JIN, CHOI, YOUN WOONG, SONG, HEE YONG, KIM, JONG IL, KIM, YONG HEE, LIM, MYOUNG HWA, KIM, MIN SOO, HA, DAE CHUL
Принадлежит:

A capsule formulation comprising mosapride citrate of the present invention can be safely used without arrhythmia and psychogenic sudden death, and without side effects such as side effects of the central nervous system, hyperprolactinemia, etc. In addition, a manufacturing process is simple in comparison with the conventional double-layered tablet or a capsule formulation, and reducing the risk of corruption and degeneration caused by microorganisms or the like, with an active ingredient filled in a capsule in comparison with the general tablet. Moreover, the formulation has effects in having similar patterns with elution profiles represented in a double-layered tablet. COPYRIGHT KIPO 2015 (BB) Sustained release unit(Mini refined form) (AA) Rapid release unit(Granular form) ...

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Номер записи: 20
15-06-2017 дата публикации

ENVIRONMENT-FRIENDLY DIATOMITE FINISHING MATERIAL COMPOSITION, PREPARATION METHOD THEREOF AND SPRAY COATING CONSTRUCTION METHOD USING SAME

Номер: KR101742918B1
Автор: LEE, CHANG MOOK, SONG, HEE YONG
Принадлежит: HONGSUNGENG CO., LTD., SONG, HEE YONG

The present invention relates to an environment-friendly diatomite finishing material composition, a preparation method thereof and a spray coating construction method using the same and, more specifically, relates to an environment-friendly diatomite finishing material composition comprising 1-10 parts by weight of a thickener with respect to 100 parts by weight of total composition comprising, at a weight ratio of 40:60 to 60:40, a paint composition containing 40-60 wt% of a first binder and 40-60 wt% of a paint mixture and a coat composition containing 40-60 wt% of a second binder and 40-60 wt% of a coat mixture, and a preparation method thereof and a spray coating construction method using the same. According to the present invention, the environment-friendly diatomite finishing material composition is excellent in adsorption and decomposition of harmful substances, deodorization, humidity control, and antibacterial and antifungal properties as a finishing material for interior use, ...

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Номер записи: 21
03-01-2019 дата публикации

신규한 용출 파라미터를 이용한 모사프리드 함유 서방제제

Номер: KR1020190000659A
Автор: 김병진, 송희용, 최연웅, 하대철, 권인호, 김용희
Принадлежит:

... 본 발명의 모사프리드 또는 이의 염을 함유하는 경구투여 서방성 이층정제는 신속한 약리활성 발현과 24시간 동안 약리 활성의 지속을 동시에 충족시키기 위하여, 약물을 신속하게 용출되도록 하는 속방층과 서서히 용출되도록 하는 서방층으로 이루어진 서방성 이층정제로서, 최적의 방출조절제를 사용하여 용출률 및 위장관에서의 체류시간을 제어하는 것이 특징이다. 또한, 본 발명은 환자의 체질 특성에 따른 맞춤형 조성을 제공하기 위해 체내 용출 양상을 예측하기 위한 신규한 인자를 제공하며, 복약순응도가 높고, 우수한 약리 효과를 보이는 모사프리드 함유 경구투여 서방성 이층정제의 제조 방법을 제공한다.

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Номер записи: 22
14-09-2017 дата публикации

PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION COMPRISING (±)-2-[2-(3-CARBOXYPROPIONYLOXY)-3-DIMETHYLAMINOPROPOXY]-3'-METHOXYBIBENZYL OR SALTS THEREOF

Номер: WO2017155350A1
Автор: CHOI, Youn Woong, HA, Dae Chul, KWON, In Ho, KIM, Ah Young, SONG, Hee Yong, JUNG, Rae Hoon, CHOI, Bo Ram
Принадлежит:

One aspect of the present invention provides a pharmaceutical composition comprising (±)-2-[2-(3-carboxypropionyloxy)-3-dimethylaminopropoxy]-3'-methoxybibenzyl hydrochloride as an active ingredient.

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Номер записи: 23
29-12-2016 дата публикации

COMPOSITE PREPARATION OF MOSAPRIDE AND RABEPRAZOLE

Номер: WO2016209061A1
Автор: CHOI, Youn Woong, SONG, Hee Yong, HA, Dae-Chul, KIM, Byung Jin, YI, Eun Hae, KIM, Yong Hee, LIM, Myoung-Hwa, KIM, Min Soo
Принадлежит:

The present invention relates to a composite preparation, with various dosage forms, of mosapride and rabeprazole. The composite preparation prepared according to the present invention allows a rapid release of drug without the deterioration of release by an interaction of mosapride and rabeprazole, thereby exhibiting an improved drug release rate and bioavailability and having excellent product stability, and significantly lowers the excipient content, thereby improving drug compatibility of a patient due to the size of the dosage form.

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Номер записи: 24
24-08-2018 дата публикации

모사프리드와 라베프라졸의 복합제제

Номер: KR0101882946B1
Автор: 최연웅, 송희용, 하대철, 김병진
Принадлежит: 한국유나이티드제약 주식회사

... 본 발명은 다양한 제형을 갖는 모사프리드와 라베프라졸의 복합 제제에 관한 것이다. 본 발명에 따라 제조된 복합 제제는 모사프리드 및 라베프라졸의 상호작용에 의한 용출저하 현상 없이 약물의 속방성 방출을 가능하게 하여 향상된 약물의 용출률 및 생체이용률을 나타낼 뿐만 아니라, 제품 안정성이 우수하고, 부형제의 함량을 크게 낮출 수 있어 제형 크기로 인한 환자의 복약순응도를 높일 수 있다.

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Номер записи: 25
18-01-2016 дата публикации

SOLID PREPARATION CONTAINING CHOLINE ALFOSCERATE AND PREPARING METHOD THEREOF

Номер: KR1020160005971A
Автор: CHOI, YOUN WOONG, MIN, BYUNG GU, KI, DO HYOUNG, JUN, HYUNG JOON, CHOI, EUN JUNG, CHO, SANG MIN, HA, DAE CHUL, PARK, HEE CHAN, SONG, HEE YONG
Принадлежит:

The present invention relates to a solid preparation comprising choline alfoscerate and calcium silicate by calcium silicate adsorbing choline alfoscerate, and to a manufacturing method thereof. The solid preparation comprising choline alfoscerate and calcium silicate has has less possibilities of being spoiled by microorganisms or having stability reduced by moisture, and has small volume to have excellent administration convenience compared with a soft capsule preparation. The solid preparation comprising choline alfoscerate and calcium silicate of the present invention uses two or more mixed disintegrating agents to improve initial elution rate to have an elution profile having the level same to an existing soft capsule preparation, thereby not having difference in an aspect of expression of a drug effect. COPYRIGHT KIPO 2016 ...

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Номер записи: 26
03-07-2017 дата публикации

오메가-3 지방산 에스테르 및 스타틴계 약물을 포함하는 경구용 복합제제

Номер: KR0101752700B1
Автор: 최연웅, 민병구, 하대철, 조상민, 송희용, 박희찬, 권인호, 김아영, 양승진
Принадлежит: 한국유나이티드제약 주식회사, 사단법인 유나이티드사이언스알앤디센터

... 본 발명은 오메가-3 지방산 에스테르 및 스타틴 계열 약물을 포함하는 약제학적 복합제제에 관한 것이다. 본 발명에 따른 경구용 복합제제는 오메가-3 지방산 에스테르를 포함하는 캡슐제 내부에, 스타틴 계열 약물이 포함된 정제를 함입하고 있으므로 원천적으로 수분, 낮은 pH 등 외부 환경과의 접촉이 완전히 차단되며, 높은 안정성과 우수한 붕해율 및 용출율을 보이는 장점이 있다.

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Номер записи: 27
16-08-2017 дата публикации

ORAL COMPLEX PREPARATION COMPRISING FAT-SOLUBLE DRUG AND SOLID FORMULATION COATED WITH OIL-PROOF MATERIAL

Номер: KR1020170093643A
Автор: CHOI, YUN WOONG, HA, DAE CHUL, KWON, IN HO, KIM, BYUNG JIN, SONG, HEE YONG, KWON, MIN SEOK, MIN, BYUNG GU, CHO, SANG MIN, JANG, JAE SANG
Принадлежит:

The present invention relates to an oral complex preparation comprising a capsule containing a fat-soluble first drug; and a solid formulation inserted into the capsule, including an oil-proof material coating layer on the surface, and containing a second drug. By using the oral complex preparation, obtained by inserting a formulation which contains a second drug including an oil-proof material coating layer on the surface into a capsule which contains a fat-soluble first drug, two kinds of drugs can be administered simultaneously, and at this time, an active ingredient of the solid formulation can be prevented from being eluted by the fat-soluble first drug or causing side reactions with the fat-soluble first drug due to the oil-proof material coating layer on the surface. Therefore, each of the two active ingredients can be independently delivered to a desired site without loss of the active ingredient. COPYRIGHT KIPO 2017 ...

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Номер записи: 28
26-10-2017 дата публикации

(±)-2-[2-(3-카르복시프로피오닐옥시)-3-디메틸아미노프로폭시]-3'-메톡시비벤질 또는 그의 염을 포함하는 경구용 약학 조성물

Номер: KR0101790286B1
Автор: 최연웅, 하대철, 권인호, 김아영, 송희용, 정래훈, 최보람
Принадлежит: 한국유나이티드제약 주식회사

... 본 발명의 일 양상은 유효성분으로서 (±)-2-[2-(3-카르복시프로피오닐옥시)-3-디메틸아미노프로폭시]-3'-메톡시비벤질 하이드로클로라이드를 포함하는, 만성 동맥폐색증에 의한 허혈성 증상 개선 또는 치료용 약학 조성물을 제공한다.

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Номер записи: 29
04-06-2018 дата публикации

BIG DATA PLATFORM LINKING APPARATUS AND LINKING METHOD THEREOF

Номер: KR1020180059269A
Автор: SONG, HEE YONG
Принадлежит:

A big data platform linking apparatus and a linking method thereof are disclosed. In the apparatus, a metadata processing unit receives metadata from a first database which provides the metadata that is setting information corresponding to a user, transmits the received metadata to a distributed file system in the big data platform, and directly stores the metadata in the distributed file system. A result transmitting unit directly reads and obtains analysis result data after a query analysis by the big data platform, from the distributed file system, and transmits the obtained analysis result data to a second database. A scheduler controls the time and order of tasks performed by the metadata processing unit and the result transmitting unit. Accordingly, the present invention can save a resource and provide fast performance. COPYRIGHT KIPO 2018 (100) Hadoop system (130) Analysis performing unit (400) Linking apparatus (410) Metadata processing unit (420) Query receiving unit (430) Query ...

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Номер записи: 30
06-07-2015 дата публикации

MOSAPRIDE CITRATE SUSTAINED-RELEASE FORMULATION FOR EASILY CONTROLLING DRUG RELEASE WITH RESEPCT TO NEEDS

Номер: KR1020150075962A
Автор: KIM, BYUNG JIN, CHOI, YOUN WOONG, SONG, HEE YONG, KIM, JONG IL, KIM, YONG HEE, LIM, MYOUNG HWA, KIM, MIN SOO, HA, DAE CHUL
Принадлежит:

A mosapride citrate multilayer tablet formulation of the present invention is capable of continuously maintaining active therapeutic blood concentrations for 24 hours as reaching rapid active therapeutic blood concentrations during administration with the same pharmaceutical activation in comparison with the existing sustained-release formulation administered once-per-day single dosage, manufacturing a drug layer only with active ingredients such as mosapride or the like and a pharmaceutically acceptable bonding layer such as lactose or the like for a simple manufacturing process, and having effects in easily controlling an amount of drug eluted with respect to needs due to elution in consecutive order with respect to viscosity of the used swelling polymer layer. COPYRIGHT KIPO 2015 (AA) Drug layer 1 (BB) Drug layer 2 (CC) Drug layer n (DD) Each swelling polymer with different viscosity (EE) Mosapride + Lactose ...

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Номер записи: 31
06-07-2015 дата публикации

SUSTAINED-RELEASE MATRIX PREPARATION COMPRISING MOSAPRIDE CITRATE WITH PELLETS DISPERSED IN MATRIX AND PREPARATION METHOD THEREOF

Номер: KR1020150075960A
Автор: KIM, BYUNG JIN, CHOI, YOUN WOONG, SONG, HEE YONG, KIM, JONG IL, KIM, YONG HEE, LIM, MYOUNG HWA, KIM, MIN SOO, HA, DAE CHUL
Принадлежит:

In the present invention, a capsule preparation comprising mosapride citrate can be safely used without worries of arrhythmia and psychogenic sudden death, and without side effects such as side effects of the central nervous system, hyperprolactinemia, etc. In addition, control of elution time, in comparison to the conventional sustained-release matrix preparation, is capable of controlling, in a relatively accurate manner, and representing a pattern similar to the Zero-order. COPYRIGHT KIPO 2015 (BB) Coating layer (AA) Pellet ...

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Номер записи: 32
21-01-2016 дата публикации

3-layered tablet containing Mosapride citrate sustained-release formulation for treating diseases in gastrointestinal tract

Номер: KR0101587142B1
Автор: 김병진, 최연웅, 송희용, 김종일, 김용희, 임명화, 김민수, 하대철
Принадлежит: 한국유나이티드제약 주식회사

... 본 발명은 모사프리드 구연산염, 충진제, 붕해제, 결합제를 포함하는 속방층과 모사프리드 구연산염, 충진제, 결합제, 붕해제, 방출제어용기제를 포함하는 두 개의 서방층으로 이루어진 삼층정으로서 활택제를 포함하고 선택적으로 결합제를 더 포함할 수 있는 경구투여용 서방정을 제공한다. 본 발명의 모사프리드 구연산염 서방제제는 1일 1회 복용되는 종래의 서방정 제제와 비교하여 투여시 초기에 유효혈중농도에 도달하는 시간을 줄이고, 아울러 약물의 용출이 24시간 동안 지속적으로 유지될 수 있도록 하기 위한 위장관 질환 치료용 모사프리드 구연산염 삼중층 서방제제인 것을 특징으로 함으로써 복용시 신속한 유효 치료혈중농도 도달 및 지속적인 유효 치료혈중농도를 유지하게 하여 치료효과를 상승시키며, 환자의 투여 요법을 단순화하여 환자에게 복용의 편의성 및 복용의 순응도를 향상시킬 수 있는 경구용 모사프리드 구연산염 서방성 제제를 제공하기 위한 것이다. 또한, 본 발명의 삼중층 서방제제는 종래의 기술인 속방층과 서방층으로 이루어진 이중층 제제에 비하여, 약물의 초기 유효혈중농도에 도달하는 시간은 동일하나 약물의 용출 지연시간을 보다 더 용이하게 조절할 수 있다는 특징이 있다.

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Номер записи: 33
19-01-2018 дата публикации

실시간 읽기 방법 및 그 장치

Номер: KR0101820521B1
Автор: 송희용
Принадлежит: 주식회사 이롬테크놀로지

... 실시간 읽기 방법 및 그 장치가 개시된다. 본 방법은 실시간 읽기 장치가 복수의 데이터를 실시간으로 수집하는 실시간 수집 서버로부터 데이터를 실시간으로 읽기 위한 방법이다. 먼저, 실시간 읽기 장치는 상기 실시간 수집 서버로부터 데이터의 스트리밍 읽기가 가능한 원격 접속을 수행한다. 그 후, 상기 원격 접속 기반 하에 일정 시간 주기의 순환 구조를 사용하여 상기 실시간 수집 서버로부터 데이터의 실시간 읽기를 수행한다.

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Номер записи: 34
24-08-2017 дата публикации

REAL-TIME READING METHOD AND APPARATUS THEREOF

Номер: KR1020170096563A
Автор: SONG, HEE YONG
Принадлежит:

Disclosed are a real-time reading method and an apparatus thereof. The real-time reading method is a method that a real-time reading apparatus reads data in real time from a real-time collection server collecting a plurality of pieces of data in real time. The real-time reading apparatus performs a remote connection capable of reading streaming data from the real-time collection server, and reading data from the real-time collection server in real time by using a circulation structure of a certain time period in the remote connection. COPYRIGHT KIPO 2017 (A1,A2) Yes (B1,B2) No (S100) Record data of a line unit (S110) Allocate an SSH agent (S120) Allocate an Sftp subagent according to the number of files (S130) Open an SSH connection (S140) Open an Sftp channel (S150) Does a line to read exist? (S160) Read a file by using a streaming reader (S170) Return a null (S180) Memorize a position of a read stream (S190) Close the Sftp channel (S200) Satisfy a time condition? (S210) Close the Sftp ...

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Номер записи: 35
29-07-2015 дата публикации

MOBILE DEVICE USING MULTIPLE CAMERA AND CONTROL METHOD THEREOF

Номер: KR1020150086840A
Автор: LEE, JONG WOO, MOON, HYE JIN, SONG, HEE YONG
Принадлежит:

According to an embodiment of the present invention, a method for controlling a terminal including a camera includes the steps of: receiving an image captured by the camera; extracting the information regarding one or more target objects from the received image; calculating the distance between the target objects and the terminal based on the extracted information regarding the target objects; and outputting an audio signal determined based on the calculated distance between the target objects and the terminal. The present invention can determine the information regarding the terminal and adjacent objects based on the image information received to multiple visual input devices and provides an audio output based on the determined information. The present invention uses different valid identification distance and identification methods according to the distance to the adjacent objects to provide the information regarding different adjacent objects according to the behavior patterns of a user ...

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Номер записи: 36
08-12-2016 дата публикации

PHARMACEUTICAL COMPOSITE PREPARATION

Номер: WO2016195153A1
Автор: CHOI, Youn Woong, MIN, Byung Gu, HA, Dea Chul, CHO, Sang Min, SONG, Hee Yong, PARK, Hee Chan, JANG, Jae Sang, KWON, In Ho, KIM, Ah Young, YANG, Seung Jin, YU, Keoun Hui
Принадлежит:

The present invention relates to a composite preparation containing clopidogrel and aspirin, and to a composite preparation having a capsule containing: a granule having a clopidogrel layer coated with an immediate-release protection layer; and an aspirin granule having an aspirin layer coated with an enteric layer. The present invention blocks physical contact between the clopidogrel and the aspirin, thereby fundamentally blocking an eutectic phenomenon, and thus, in the short-term, prevents changes in the amount, elution properties and bioequivalence of the preparation, and in the long-term, enhances the stability of the preparation, and also has the effect of preventing damage to the stomach wall by having the aspirin coated with an enteric layer. Further, a damp-proofing coating layer is included in order to enhance the stability of the moisture-sensitive clopidogrel and salt thereof, and thus the generation of clopidogrel impurities is minimized without a change in the elution amount ...

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Номер записи: 37
02-06-2017 дата публикации

ECO-FRIENDLY DIATOMACEOUS EARTH FUNCTIONAL PAINT COMPOSITION, ECO-FRIENDLY DIATOMACEOUS EARTH FUNCTIONAL PAINT PRODUCED THEREFROM, AND PRODUCING METHOD THEREOF

Номер: KR101742917B1
Автор: LEE, CHANG MOOK, SONG, HEE YONG
Принадлежит: HONGSUNGENG CO., LTD., SONG, HEE YONG

The present invention relates to an eco-friendly diatomaceous earth functional paint composition, an eco-friendly diatomaceous earth paint produced therefrom, and a producing method thereof. More specifically, an eco-friendly functional paint composition comprises 40 to 60 wt% of a binder, and 40 to 60 wt% of a paint mixture. The binder includes 15 to 50 wt% of a lithium silicate aqueous solution, 20 to 50 wt% of a re-oiling type dispersion resin, 1 to 5 wt% of a surfactant, and 29 to 59 wt% of water with respect to 100 wt% of the total binder. The paint mixture includes 50 to 78 wt% of diatomaceous earth, 5 to 20 wt% of calcium carbonate, 5 to 20 wt% of talc, 3 to 15 wt% of titanium dioxide, 1 to 10 wt% of a natural thickener, 1 to 5 wt% of a pigment dispersant, 1 to 5 wt% of a high plasticizer, and 1 to 5 wt% of a defoaming agent with respect to 100 wt% of the total paint mixture. According to the present invention, the eco-friendly diatomaceous earth functional paint can be used as an ...

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Номер записи: 38
18-04-2016 дата публикации

Mosapride sustained-release formulation for providing pharmaceutical clinical effects with once-a-day dosing

Номер: KR0101612931B1
Автор: 김병진, 최연웅, 송희용, 김종일, 김용희, 임명화, 김민수, 하대철
Принадлежит: 한국유나이티드제약 주식회사

... 본 발명의 모사프리드 또는 이의 염을 함유하는 경구투여 제제는 신속한 약리활성 발현과 24시간 동안 약리 활성의 지속을 동시에 충족시키기 위하여, 약물을 신속하게 방출되도록 하는 속방층과 서서히 방출되도록 하는 서방층으로 이루어진 이층형 제제로서, 서방층 내 방출제어 기제로 고점도의 하이드록시프로필메틸셀룰로오스(HPMC) 비율이 많도록 고점도 하이드록시프로필메틸셀룰로오스(HPMC) 및 저점도 하이드록시프로필메틸셀룰로오스(HPMC)를 혼합사용하여 pH가 상이한 각 위장관 내 부위에서의 용출률 및/또는 위장관에서의 체류시간을 제어하는 것이 특징이다. 또한, 본 발명은 총 중량이 200mg 이하, 바람직하게는 150 내지 160mg의 작은 제제크기여서, 환자의 복약 순응도를 증진시키는 장점이 있다.

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Номер записи: 39
07-04-2017 дата публикации

ENVIRONMENT-FRIENDLY INORGANIC ADHESIVE COMPOSITION AND METHOD FOR PREPARING SAME

Номер: KR101723777B1
Автор: LEE, CHANG MOOK, SONG, HEE YONG
Принадлежит: HONGSUNGENG CO., LTD., SONG, HEE YONG

The present invention relates to an environment-friendly inorganic adhesive composition and a method for preparing the same. Specifically, the environment-friendly inorganic adhesive composition comprises a main component and a curing agent, wherein the main component comprises 50-81 wt% of calcium aluminate; 1-25 wt% of an anhydrous gypsum; 5-25 wt% of white Portland cement; 1-5 wt% of a curing accelerator; 0.1-5 wt% of a curing retarding agent; 1-10 wt% of a thickening agent; 5-15 wt% of cellulose fibers; 1-10 wt% of a thickening agent; and 1-5 wt% of an antifoaming agent, while the curing agent comprises: 69-90 wt% of poly(vinyl alcohol); 8-30 wt% of a functional component; and 1-5 wt% of a curing agent. The present invention provides an environment-friendly inorganic adhesive composition and a method of preparing the same, which do not generate environmental pollutants such as total volatile organic compounds (TVOC) and 5 volatile organic compounds (5VOCs) including toluene, formaldehyde ...

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Номер записи: 40
10-08-2017 дата публикации

ORAL COMPOSITE FORMULATION COMPRISING FAT-SOLUBLE DRUG AND SOLID PREPARATION COATED WITH OIL REPELLENT BASE

Номер: WO2017135739A1
Автор: CHOI, Yun Woong, HA, Dae Chul, KWON, In Ho, KIM, Byung Jin, SONG, Hee Yong, KWON, Min-Seok, MIN, Byung Gu, CHO, Sang Min, JANG, Jae Sang
Принадлежит:

The present invention relates to an oral composite formulation comprising: a capsule containing a first drug with fat solubility; and a solid preparation containing a second drug, the solid preparation being inserted inside the capsule and including an oil repellent base coating layer on a surface thereof. The oral composite formulation of the present invention, which comprises a capsule containing a first drug with fat solubility and a solid preparation inserted inside the capsule, the solid preparation including an oil repellent base coating layer on a surface thereof and containing a second drug, allows a simultaneous administration of two types of ingredient drugs, and here, the oil repellent base coating layer on the surface can prevent an active ingredient of the solid preparation from being released by the first drug with fat solubility and causing side reactions with the first drug with fat solubility, thereby delivering two types of active ingredients independently to desired sites ...

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Номер записи: 41
03-08-2016 дата публикации

매트릭스와 코팅층에 모사프리드가 포함된 위장관 질환 치료용 서방형 매트릭스 제제 및 그 제조방법

Номер: KR0101645313B1
Автор: 김병진, 최연웅, 송희용, 김종일, 김용희, 임명화, 김민수, 하대철
Принадлежит: 한국유나이티드제약 주식회사

... 본 발명은 위장관 질환의 개선 효과를 나타내는 모사프리드 함유 경구 투여 서방형 매트릭스 제제의 제조 방법에 관한 것이다.본 발명은 종래의 서방형 매트릭스 제제의 방법과는 다르게 유효성분, 부형제, 붕해제, 서방형 기제 및 첨가제를 포함하는 매트릭스 제제의 표면에 유효성분과 코팅 기제를 포함하는 코팅층으로 구성된 모사프리드 함유 서방형 매트릭스 제제의 구조를 가진다.본 발명은 매트릭스에 유효성분과 각종 첨가제가 함유되어 있어 코팅층과 매트릭스가 각각 속방층과 서방층의 효과를 나타낼 수 있는 장점을 가진다.

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Номер записи: 42
08-05-2017 дата публикации

ECO-FRIENDLY DIATOMITE BOARD COMPOSITION, ECO-FRIENDLY DIATOMITE BOARD MANUFACTURED THEREBY, AND MANUFACTURING METHOD THEREOF

Номер: KR101732852B1
Автор: LEE, CHANG MOOK, SONG, HEE YONG
Принадлежит: HONGSUNGENG CO., LTD., SONG, HEE YONG

The present invention relates to an eco-friendly diatomite board composition, an eco-friendly diatomite board manufactured thereby, and a manufacturing method thereof, and more specifically, to an eco-friendly diatomite board composition comprising 60-80 wt% of inorganic binders and 20-40 wt% of functional compounds, an eco-friendly diatomite board manufactured thereby and a manufacturing method thereof. The inorganic binders comprise, based on a total of 100% by weight, 55-90 wt% of calcium aluminate, 5-40 wt% of micro cement, 1-5 wt% of hardening accelerator, 1-5 wt% of hardening retardant, 1-5 wt% of cellulose fiber, 0.1-5 wt% of superplasticizer, 0.1-2 wt% of antifoaming agents, 0.5-5 wt% of dispersants and 1-5 wt% of viscosity agents. The functional compounds comprise, based on a total of 100% by weight, 80-97 wt% of diatomite, 2-6 wt% of anion generating materials and 1-14 wt% of inorganic antimicrobial. According to the present invention, provided are an eco-friendly diatomite board ...

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Номер записи: 43
21-01-2016 дата публикации

Capsule containing mini-tablets comprising mosapride citrate for sustained-releasing formulation improving gastrointestinal disease and preparing the method thereof

Номер: KR0101587140B1
Автор: 김병진, 최연웅, 송희용, 김종일, 김용희, 임명화, 김민수, 하대철
Принадлежит: 한국유나이티드제약 주식회사

... 본 발명의 모사프리드 구연산염을 포함하는 캡슐 제제의 경우, 부정맥 및 심인성 급사의 우려가 없고, 중추신경계 부작용, 고프롤락틴혈증 등의 부작용이 없어 안전하게 사용할 수 있다. 또한 종래의 이중정 또는 캡슐 제제에 비하여 제조 공정이 단순하고, 보통의 정제와는 달리 유효성분이 캡슐에 충전되어 있어 미생물 등에 의한 오염 및 변질의 위험이 적다. 그리고, 이중정에서 보여지는 용출 프로파일과 유사한 패턴을 가진다는 효과가 있다.

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Номер записи: 44
07-08-2017 дата публикации

약제학적 복합제제

Номер: KR0101764785B1
Автор: 최연웅, 민병구, 하대철, 조상민, 송희용, 박희찬, 장재상, 권인호, 김아영, 양승진, 유권희
Принадлежит: 한국유나이티드제약 주식회사

... 본 발명은 클로피도그렐과 아스피린을 포함하는 복합제제에 관한 것으로, 클로피도그렐층을 속방보호층으로 코팅한 과립과 아스피린층을 장용층으로 코팅한 아스피린 과립을 캡슐에 담은 복합제제에 관한 것이다. 본 발명은 클로피도그렐과 아스피린의 물리적 접촉을 차단함으로써, 공융(eutectic)현상을 원천적으로 차단하여, 단기적으로 제제의 함량, 용출특성, 생물학적 동등성(bioequivalence)의 변화를 방지하고, 장기적으로 제제의 안정성을 제고할 뿐만 아니라, 아스피린을 장용층으로 코팅하여 위벽 손상을 예방하는 효과가 있다. 또한, 수분에 민감한 클로피도그렐 및 그의 염의 안정성 향상을 위해 방습코팅층을 포함하여 클로피도그렐 용출량에는 변화없이 클로피도그렐 유연물질의 생성을 최소화하였다. 또한, 본 발명은 건조처리와 같은 제조상의 부가 공정을 거치지 않고도 클로피도그렐에 함유된 잔류 용매량을 현저히 감소시킬 수 있기 때문에, 간단한 공정으로 생산 비용을 절감하는 효과가 있다.

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Номер записи: 45
10-05-2016 дата публикации

ANTITUSSIVE AND EXPECTORANT COMPOSITION, COMPRISING MIXED EXTRACT OF RHIZOMA COPTIDIS AND PELARGONIUM SIDOIDES

Номер: KR1020160050006A
Автор: CHOI, YOUN WOONG, MIN, BYUNG GU, HA, DAE CHUL, CHO, SANG MIN, SONG, HEE YONG, PARK, HEE CHAN, KI, DO HYOUNG, JUNG, WON TAE, NAM, KYU YEOL
Принадлежит:

The present invention relates to a usage of a mixed extract of Rhizoma Coptidis and Pelargonium sidoides as an antitussive and expectorant composition, and to a usage of preventing or treating respiratory diseases or respiratory infections. COPYRIGHT KIPO 2016 ...

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Номер записи: 46
03-01-2019 дата публикации

신규한 용출 파라미터를 사용한 모사프리드 함유 서방제제

Номер: KR1020190000656A
Автор: 김병진, 송희용, 최연웅, 하대철, 권인호, 김용희
Принадлежит:

... 본 발명의 모사프리드 또는 이의 염을 함유하는 경구투여 서방성 이층정제는 신속한 약리활성 발현과 24시간 동안 약리 활성의 지속을 동시에 충족시키기 위하여, 약물을 신속하게 용출되도록 하는 속방층과 서서히 용출되도록 하는 서방층으로 이루어진 서방성 이층정제로서, 최적의 방출조절제를 사용하여 용출률 및 위장관에서의 체류시간을 제어하는 것이 특징이다. 또한, 본 발명은 환자의 체질 특성에 따른 맞춤형 조성을 제공하기 위해 체내 용출 양상을 예측하기 위한 신규한 인자를 제공하며, 복약순응도가 높고, 우수한 약리 효과를 보이는 모사프리드 함유 경구투여 서방성 이층정제의 제조 방법을 제공한다.

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Номер записи: 47
14-01-2016 дата публикации

SOLID PREPARATION COMPRISING CHOLINE ALFOSCERATE AND METHOD FOR PREPARING SAME

Номер: WO2016006862A1
Автор: CHOI, Youn Woong, MIN, Byung Gu, KI, Do Hyoung, JUN, Hyung Joon, CHOI, Eun-Jung, CHO, Sang Min, HA, Dae-Chul, PARK, Hee-Chan, SONG, Hee-Yong
Принадлежит:

The present invention relates to a solid preparation comprising choline alfoscerate and calcium silicate and a method for preparing the same, wherein calcium silicate adsorbs choline alfoscerate and thereby enables formulation in a solid form. Compared to soft capsule formulations, the solid preparation of the present invention, comprising choline alfoscerate and calcium silicate, has advantages of there being less concern regarding deterioration due to microorganisms and stability degradation due to moisture, and of being excellent in the ease of dosing because of a smaller volume. In addition, the present invention improves the initial dissolution rate of the solid preparation by using two or more disintegrants by mixture and thereby exhibits the same level of dissolution profile as conventional soft capsule formulations, and therefore is not different therefrom in the expression of a medicinal effect.

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Номер записи: 48
21-02-2019 дата публикации

지용성 약물 및 방유성 기제가 코팅된 고형제제를 포함하는 경구용 복합제제

Номер: KR0101950907B1
Автор: 최연웅, 하대철, 권인호, 김병진, 송희용, 권민석, 민병구, 조상민, 장재상
Принадлежит: 한국유나이티드제약 주식회사, 사단법인 유나이티드사이언스알앤디센터

... 본 발명은 지용성 제1약물 함유 캡슐제; 및 상기 캡슐제 내부에 함입되어 있고, 표면에 방유성 기제 코팅층을 포함하는, 제2약물을 함유하는 고형제제를 포함하는 경구용 복합제제에 관한 것이다. 본 발명의 지용성 제1약물 함유 캡슐제에 상기 캡슐제 내부에 표면에 방유성 기제 코팅층을 포함하는, 제2약물을 함유하는 고형제제를 함입시킨 경구용 복합제제는 2종 성분의 약물을 동시에 투여할 수 있고, 이때 표면에 방유성 기제 코팅층으로 인해 고형제제의 유효성분이 지용성 제1약물에 의해 용출되거나 지용성 제1약물과 부반응을 일으키는 것을 차단할 수 있으므로, 유효성분의 손실 없이 원하는 부위에 독립적으로 2종의 유효성분을 각각 전달할 수 있다.

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Номер записи: 49
28-12-2016 дата публикации

COMPOSITION FOR ARTHRITIS PREVENTION, ALLEVIATION, OR TREATMENT CONTAINING BOSWELLIA SERRATA EXTRACT, GRAPE SEED EXTRACT, AND JUNIPER BERRY EXTRACT AS ACTIVE INGREDIENTS

Номер: KR1020160149664A
Автор: KIM, SOO HWAN, HA, DAE CHUL, AHN, JUN HO, CHANG, YONG HA, SONG, HEE YONG, KIM, BYUNG JIN, KWON, IN HO, CHOI, YOUN WOONG, KIM, JUN HO, PARK, KEON WOONG, KIM, HYUNG MIN, LEE, EUI SEOP, LEE HYE JUNG
Принадлежит:

The present invention relates to a composition for arthritis prevention, alleviation, or treatment containing an herb medicine-extracted mixture as an active ingredient and, more particularly, to a composition for arthritis prevention, alleviation, or treatment containing a boswellia serrata extract, a grape seed extract, and a juniper berry extract as active ingredients. The herb medicine-extracted mixture according to the present invention has suppressed the generation of nitric oxide (NO) as an inflammatory material, prostaglandin E2 (PGE2), and inflammatory cytokine. It not only suppresses arthritis in an arthritic animal model but also reduces the degree of cartilaginous tissue damage. Accordingly, it can be effectively used in the composition for arthritis prevention, alleviation, or treatment. COPYRIGHT KIPO 2017 ...

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Номер записи: 50
06-05-2016 дата публикации

ANTITUSSIVE AND EXPECTORANT COMPOSITION CONTAINING, AS ACTIVE INGREDIENT, MIXTURE EXTRACT OF COPTIDIS RHIZOME AND PELARGONIUM SIDOIDES

Номер: WO2016068607A1
Автор: CHOI, Youn Woong, MIN, Byung Gu, HA, Dae Chul, CHO, Sang Min, SONG, Hee Yong, PARK, Hee Chan, KI, Do Hyoung, JUNG, Won Tae, NAM, Kyu Yeol
Принадлежит:

The present invention relates to a use of a mixture extract of Coptidis rhizome and Pelargonium Sidoides as anantitussive or expectorant agent, and a use of the same for preventing or treating respiratory diseases or respiratory infection.

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Номер записи: 51
18-02-2016 дата публикации

ORAL COMBINED PREPARATION CONTAINING OMEGA-3 FATTY ESTER AND STATIN-BASED DRUG

Номер: WO2016024844A1
Автор: CHOI, Youn Woong, HA, Dae Chul, CHO, Sang Min, SONG, Hee Yong, KWON, In Ho, YANG, Seung Jin, MIN, Byung Gu, PARK, Hee Chan, KIM, Ah Young
Принадлежит:

The present invention relates to a pharmaceutical combined preparation containing an omega-3 fatty ester and a statin-based drug. The oral combined preparation according to the present invention contains, a tablet containing a statin-based drug, inside a capsule agent containing an omega-3 fatty acid ester, and thus, the oral combined preparation is fundamentally and completely cut off from contact with an external environment, including moisture, low pH, and the like, thereby showing high stability and excellent disintegration and dissolution rates.

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Номер записи: 52
30-06-2017 дата публикации

CONTINUOUS DATA COLLECTING AND STORING METHOD AND SYSTEM THEREFOR

Номер: KR1020170074663A
Автор: SONG, HEE YONG
Принадлежит:

Disclosed are a continuous data collecting and storing method and a system therefor. In a first step of the method, an input plugin defined for a plurality of data sources performs a detection operation on the plurality of data sources according to the definition. In a second step, an agent plugin detects actual data in the plurality of data sources according to the state of the plurality of data sources as a result of the detection operation by the input plugin. In a third step, a subagent plugin performs processing on data while reading the data from the plurality of data sources according to the detection result of the agent plugin. In a fourth step, an output plugin compresses the data processed by the subagent plugin, converts the data into a storage format, and stores the data in a storage system. The present invention can easily prevent duplication and loss of data when collecting and storing continuous data so that a failure can be easily recovered to maintain data integrity. COPYRIGHT ...

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Номер записи: 53
18-09-2014 дата публикации

MOSAPRIDE SUSTAINED-RELEASE PREPARATION FOR PROVIDING PHARMACOLOGICAL CLINICAL EFFECTS WITH ONCE-A-DAY ADMINISTRATION

Номер: WO2014142616A1
Автор: KIM, Byung Jin, CHOI, Youn Woong, SONG, Hee Yong, KIM, Jong-Il, KIM, Yong Hee, LIM, Myoung-Hwa, KIM, Min Soo, HA, Dae-Chul
Принадлежит:

A preparation for oral administration of the present invention, containing mosapride or salt thereof, is a double-layer preparation consisting of an immediate-release layer which allows drug to be rapidly released, and a sustained-release layer which allows drug to be slowly released, in order to simultaneously satisfy a rapid expression of pharmacological activity and a 24-hour duration of pharmacological activity, and is characterized by controlling a dissolution rate of each site within the gastrointestinal tract with different pHs and/or a residence time in the gastrointestinal tract by using, in a mixed manner, high viscosity hydroxypropyl methylcellulose (HPMC) and low viscosity hydroxypropyl methylcellulose (HPMC) in such a manner that the proportion of high viscosity hydroxypropyl methylcellulose (HPMC), as a release-control base in the sustained-release layer, is higher. Furthermore, the preparation of the present invention has a small size with a total weight of 200 mg or less ...

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Номер записи: 54
27-09-2017 дата публикации

COMPLEX FORMULATION COMPRISING CLOPIDOGREL AND ASPIRIN

Номер: KR1020170108874A
Автор: CHOI, YUN WOONG, HA, DAE CHUL, SONG, HEE YONG, KWON, IN HO, JUNG, RAE HOON, YANG, SEUNG JIN, YU, KEOUN HUI, WI, TAE IN
Принадлежит:

The present invention relates to a complex formulation comprising clopidogrel and aspirin and a manufacturing method thereof. Stability is maintained even during storage and distribution, and the speed of disintegration of clopidogrel tablets is fast. The complex formulation comprises: a clopidogrel tablet including clopidogrel, an isomer thereof, or a pharmaceutically acceptable salt thereof; and an aspirin-containing particle which includes an aspirin core having aspirin, an isomer thereof, or a pharmaceutically acceptable salt thereof, and includes an enteric coating layer covering the core. COPYRIGHT KIPO 2017 ...

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Номер записи: 55
03-01-2019 дата публикации

1일 1회 경구투여하는 모사프리드 함유 서방제제

Номер: KR1020190000661A
Автор: 김병진, 송희용, 최연웅, 하대철, 권인호, 김용희
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... 본 발명의 모사프리드 또는 이의 염을 함유하는 경구투여 서방성 이층정제는 신속한 약리활성 발현과 24시간 동안 약리 활성의 지속을 동시에 충족시키기 위하여, 약물을 신속하게 용출되도록 하는 속방층과 서서히 용출되도록 하는 서방층으로 이루어진 서방성 이층정제로서, 최적의 용출 양상을 나타내기 위하여, 치환도에 따라 용출 특성이 상이한 수 종의 용출 제어 기제를 방출조절제로 사용하며, pH가 상이한 각 위장관 내 부위에서의 용출률 및 위장관에서의 체류시간을 제어하는 것이 특징이다. 또한, 본 발명은 환자의 복약 순응도를 높이면서, 질환으로 인하여 소화계 기능이 저하되거나 소화가 느린 체질의 환자에게 투여하기 위해 통상적인 환자보다 장기간에 걸쳐 효과가 지속되도록 고안된 모사프리드 함유 경구투여 서방성 이층정제의 제조 방법을 제공한다.

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Номер записи: 56
25-08-2017 дата публикации

황련 및 펠라고니움 시도이데스 혼합 추출물을 유효성분으로 포함하는, 진해 거담용 조성물

Номер: KR0101770606B1
Автор: 최연웅, 민병구, 하대철, 조상민, 송희용, 박희찬, 기도형, 정원태, 남규열
Принадлежит: 한국유나이티드제약 주식회사

... 본 발명은 황련(Coptidis rhizome) 및 펠라고니움 시도이데스(Pelargonium Sidoides) 혼합 추출물의 진해 또는 거담제로서의 용도 및 호흡기 질환 또는 기도 감염의 예방 또는 치료 용도에 관한 것이다.

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Номер записи: 57
06-07-2015 дата публикации

THREE-LAYERED MOSAPRIDE CITRATE-CONTAINING SUSTAINED-RELEASE PREPARATION INCLUDING QUICK-RELEASE LAYER AND TWO SUSTAINED-RELEASE LAYERS FOR TREATMENT OF GASTROINTESTINAL TRACT DISEASE

Номер: KR1020150075961A
Автор: KIM, BYUNG JIN, CHOI, YOUN WOONG, SONG, HEE YONG, KIM, JONG IL, KIM, YONG HEE, LIM, MYOUNG HWA, KIM, MIN SOO, HA, DAE CHUL
Принадлежит:

Provided is an orally administrable three-layered sustained-release preparation, which comprises a lubricant which consists of a quick-release layer which comprises mosapride citrate, a filler, a disintegrant and a binder, and two sustained-release layers which comprise mosapride citrate, a filler, a disintegrant and a release-regulating agent, and further selectively comprises an additional binder. A three-layered mosapride citrate-containing sustained-release preparation according to the present invention reduces the time required to reach an initial effective plasma level when administered, compared to conventional sustained-release preparation which are taken one time per day, and maintains the stable release of drugs for 24 hours, so that an effective plasma level for treatment when administered can be reached quickly and maintained reliably to enhance treatment effect and to simplify a method to administer and thus enhance convenience and compliance for a patient. In addition, compared ...

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Номер записи: 58