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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 22. Отображено 22.
21-09-2016 дата публикации

COMPOSITION FOR PREVENTING OR TREATING AUTOIMMUNE DISEASE

Номер: KR1020160109356A
Автор: RYU, KYUNG HA, RYU, JUNG HWA, WOO, SO YOUN, PARK, MIN HWA, KIM, BO KYUNG, JO, IN HO
Принадлежит:

The present invention relates to a pharmaceutical composition for preventing or treating autoimmune disease, containing tonsil-derived mesenchymal stem cells (T-MSCs) as an active ingredient. The pharmaceutical composition for preventing and treating autoimmune disease suppresses proliferation, differentiation, and maturation of B cells, resulting in regulation of an auto-immune reaction by inhibiting autoantibody production. Accordingly, the pharmaceutical composition can bring remarkable effects of preventing and treating autoimmune disease. COPYRIGHT KIPO 2016 ...

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Номер записи: 1
21-09-2016 дата публикации

COMPOSITION FOR PREVENTING OR TREATING BONE MARROW FAILURE

Номер: KR1020160109362A
Автор: RYU, KYUNG HA, WOO, SO YOUN, RYU, JUNG HWA, PARK, MIN HWA, KIM, HAN SU, KIM, YU HEE, JO, IN HO
Принадлежит:

The present invention relates to a pharmaceutical composition comprising tonsil-derived mesenchymal stem cells and myeloid cells as active ingredients for preventing or treating bone marrow failure. The pharmaceutical composition for preventing or treating bone marrow failure of the present invention shows a significant effect in restoring the state of peripheral blood, through a synergistic effect of tonsil-derived mesenchymal stem cells and myeloid cells, and can form various cell groups comprising the normal levels of white blood cells, platelets and red blood cells. Also, the pharmaceutical composition mixes and restores myeloid cells, some adipocytes and megakaryocytes in the marrow space to thereby restore the normal state of bone marrow, maintain the normal size and cell count of the spleen, and increase the CD41+ cell count to the normal level. Based on these effects, the pharmaceutical composition of the present invention can also greatly increase survival rate, and thus shows ...

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Номер записи: 2
05-12-2022 дата публикации

한우고기 함박 스테이크 및 그 제조방법

Номер: KR20220159849A
Автор: 이승제, 이중근, 박민화, 강주원
Принадлежит:

... 본 발명은 한우고기 함박 스테이크 및 그 제조방법에 관한 것으로, 본 발명에 따르면, 닭고기 및 한우를 포함하는 원료육과 액상조미료, 제1 분말조미료, 제2 분말조미료 및 야채를 포함하는 부원료를 준비하는 재료준비단계; 상기 원료육을 분쇄하는 원료육분쇄단계; 분쇄된 원료육, 액상조미료 및 제1 분말조미료를 혼합하는 제1 배합단계; 상기 제2 분말조미료 및 야채를 추가로 혼합하여 배합물을 제조하는 제2 배합단계; 상기 배합물을 스테이크 형태로 성형하는 성형단계; 성형물을 오븐 가열 또는 스팀 가열하는 가열단계 및 익혀진 성형물을 동결시키는 급속동결단계를 포함하는 한우고기 함박 스테이크 제조방법을 제공할 수 있다.

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Номер записи: 3
08-07-2015 дата публикации

ANTI-AIMP1/P43 MONOCLONAL ANTIBODY AND USE THEREOF

Номер: KR1020150078472A
Автор: KIM, SUNG HOON, CHOI, YON SIK, SHIM, HYUN BO, LEE, NAM JU, PARK, MIN HWA
Принадлежит:

The present invention relates to an anti-AIMP1/p43 antibody selectively bound to an ARS-interacting multifunctional protein 1 (AIMP1/p43) and, more specifically, to an antibody bound to human AIMP1/p43 or a fraction thereof, a production method thereof, and a pharmaceutical composition for treating cancers or a composition for diagnosing cancers and inflammatory diseases comprising the same. The antibody or the fraction thereof is specifically bound to the human AIMP1/p43 and is capable of detecting and inhibiting AIMP1/p43 due to no cross reactivity with other proteins including the same ARS family, thereby being able to be used in detecting AIMP1/p43, treating cancers related with AIMP1/p43, and diagnosing cancers and inflammatory diseases. COPYRIGHT KIPO 2015 ...

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Номер записи: 4
25-10-2017 дата публикации

편도 유래 중간엽 줄기세포 또는 이의 조정 배지를 포함하는 골다공증 예방 또는 치료용 조성물

Номер: KR0101789475B1
Автор: 김유희, 유경하, 우소연, 조경아, 박민화
Принадлежит: 이화여자대학교 산학협력단

... 본 발명은 편도 유래 중간엽 줄기세포, 이의 조정 배지 또는 이들 모두를 유효성분으로 포함하는 골다공증, 내장비만 예방 또는 치료용 약학 조성물에 관한 것이다. 본 발명의 약학 조성물은 골아세포 분화 증진, 지방 세포 분화 억제, 골수 지방 감소, 내장 지방 축적 억제, 체중 감소 효과를 보임으로써 골다공증 및/또는 내장비만에 대한 현저한 예방 및 치료 효과를 보인다.

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Номер записи: 5
05-09-2017 дата публикации

편도 유래 중간엽 줄기세포 또는 이의 조정 배지를 포함하는 피부 염증 질환 예방 또는 치료용 조성물

Номер: KR0101775262B1
Автор: 조경아, 우소연, 유경하, 김유희, 박민화
Принадлежит: 이화여자대학교 산학협력단

... 본 발명은 편도 유래 중간엽 줄기세포, 이의 조정 배지 또는 이들 모두를 유효성분으로 포함하는 피부 염증 질환 예방 또는 치료용 약학 조성물에 관한 것이다. 본 발명의 피부 염증 질환 예방 또는 치료용 약학 조성물은 PD-L1의 높은 발현 및 분비를 통해 우수한 면역 조절능을 보여 피부 염증 질환에 있어 염증 반응들을 조절함으로써 피부 염증, 특히 건선에 대한 현저한 예방 및 치료 효과를 보인다.

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Номер записи: 6
10-08-2017 дата публикации

COMPOSITION FOR PREVENTING OR TREATING OSTEOPOROSIS CONTAINING TONSIL-DERIVED MESENCHYMAL STEM CELLS OR CONDITIONED MEDIUM THEREOF

Номер: KR1020170091882A
Автор: KIM, YU HEE, RYU, KYUNG HA, WOO, SO YOUN, CHO, KYUNG AH, PARK, MIN HWA
Принадлежит:

The present invention relates to a pharmaceutical composition for preventing or treating osteoporosis and visceral obesity, containing tonsil-derived mesenchymal stem cells (T-MSCs), a conditioned medium thereof, or the same as active ingredients. The pharmaceutical composition shows effectiveness in promotion of osteoblast differentiation, suppression of adipocyte differentiation, reduction in fatty bone marrow, inhibition of visceral fat accumulation, and reduction in weight. Accordingly, the pharmaceutical composition is effective in preventing and treating osteoporosis and/or visceral obesity. COPYRIGHT KIPO 2017 ...

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Номер записи: 7
19-07-2017 дата публикации

COMPOSITION FOR PREVENTING OR TREATING SKIN INFLAMMATION DISEASE, COMPRISING TONSIL-DERIVED MESENCHYMAL STEM CELL OR CONTROL MEDIUM THEREOF

Номер: KR1020170083786A
Автор: CHO, KYUNG AH, WOO, SO YOUN, RYU, KYUNG HA, KIM, YU HEE, PARK, MIN HWA
Принадлежит:

The present invention relates to a pharmaceutical composition for preventing or treating skin inflammation diseases, which comprises a tonsil-derived mesenchymal stem cells, a control medium thereof or all of them, as an active ingredient. The pharmaceutical composition for preventing or treating skin inflammation diseases of the present invention shows excellent immunoregulatory ability through high expression and secretion of PD-L1, and shows remarkable effects of preventing and treating on skin inflammation, and especially psoriasis by controlling inflammatory reactions in skin inflammatory diseases. COPYRIGHT KIPO 2017 ...

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Номер записи: 8
14-12-2022 дата публикации

쌈소스

Номер: KR102477463B1
Автор: 이승제, 정은선, 윤나래, 박민화
Принадлежит: 재단법인 전남바이오산업진흥원

... 본 발명은 쌈소스 및 이의 제조방법에 관한 것으로, 본 발명에 따르면, 된장, 고추장, 물엿, 깨 및 참기름을 포함하는 쌈소스를 제공할 수 있다. 또한, 쌈소스를 제조하는 방법에 있어서, 된장, 고추장, 물엿, 깨 및 참기름을 포함하는 원료를 준비하는 준비단계; 준비된 원료를 혼합하는 혼합단계; 상기 원료가 혼합된 혼합물을 가열하면서 살균하는 가열단계; 상기 혼합물을 포장지에 충진시키는 충진단계 및 상기 포장지에 충진된 상기 혼합물을 냉각하는 냉각단계를 포함하는 쌈소스의 제조방법을 제공할 수 있다.

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Номер записи: 9
09-07-2015 дата публикации

ANTI-KRS MONOCLONAL ANTIBODY AND USE THEREOF

Номер: WO2015102341A1
Автор: KIM, Sunghoon, CHOI, Yon-Sik, SHIM, Hyunbo, LEE, Nam Ju, PARK, Min Hwa
Принадлежит:

The present invention relates to an anti-lysy1-tRNA synthetase (KRS) antibody selectively binding to KRS, and a use thereof and, more specifically, to an antibody binding to human KRS or a fragment thereof, a method for producing the same, and a composition containing the same for diagnosing cancer or autoimmune diseases and inflammatory diseases. The antibody or fragment thereof of the present invention specifically binds to human KRS, and enables KRS detection and inhibition due to the absence of cross-linkage reactivity with the other proteins including the same ARS family, and thus the antibody or fragment thereof can be used to detect KRS and diagnose KRS-related diseases or autoimmune diseases and inflammatory diseases.

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Номер записи: 10
26-04-2023 дата публикации

편도 유래 중간엽 줄기세포의 조정 배지를 포함하는 간질환 예방 또는 치료용 조성물

Номер: KR102526447B1
Автор: 유경하, 우소연, 박주원, 조인호, 김한수, 조경아, 김유희, 박민화
Принадлежит: 이화여자대학교 산학협력단

... 본 발명은 편도 유래 중간엽 줄기세포의 조정배지를 유효성분으로 포함하는 간질환 예방, 개선 또는 치료용 조성물에 관한 것이다. 본 발명의 간질환 예방, 개선 또는 치료용 조성물은 타유래 중간엽 줄기세포의 조정 배지와 대비하여, 조정 배지 내 면역 조절 인자, 간섬유화 억제 인자들의 상이한 프로파일을 가지고 이로 인하여 간질환의 예방, 개선 및 치료에 우수한 효과를 가진다.

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Номер записи: 11
31-01-2023 дата публикации

가정간편식 한우고기 죽 및 그 제조방법

Номер: KR20230015818A
Автор: 이승제, 이중근, 박민화, 강주원
Принадлежит:

... 본 발명은 가정간편식 한우고기 죽 및 그 제조방법에 관한 것으로, 본 발명에 따르면, 재료로 원료육, 멥쌀, 전분, 채소, 식용유, 다진마늘, 정제염, 한우고기 농축액, 닭고기 농축액, 전복 농축액, 다시마엑기스, 보일드치킨-P, 잔탄검 및 정제수를 준비하는 재료전처리단계; 원료육, 멥쌀, 전분, 채소, 식용유, 다진마늘, 정제염, 한우고기 농축액, 닭고기 농축액, 전복 농축액, 다시마엑기스, 보일드치킨-P, 잔탄검 및 정제수를 혼합하며 가열하는 조리단계 및 상기 조리단계에서 제조된 죽을 포장지에 주입하고 밀봉하여 포장하는 포장단계를 포함하되, 상기 원료육은 한우고기 및 닭고기 중 하나 이상을 포함하는 것을 특징으로 하는 가정간편식 한우고기 죽 제조방법을 제공할 수 있다.

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Номер записи: 12
22-05-2020 дата публикации

COMPOSITION, COMPRISING CONDITIONED MEDIUM OF TONSIL-DERIVED MESENCHYMAL STEM CELL, FOR INHIBITING CANCER METASTASIS

Номер: WO2020101212A1
Автор: RYU, Kyung Ha, WOO, So Youn, KIM, Han Su, PARK, Joo Won, KIM, Yu Hee, CHO, Kyung Ah, PARK, Min Hwa
Принадлежит:

The present invention relates to a composition for inhibiting cancer metastasis, or preventing, alleviating, or treating cancer, comprising a conditioned medium of tonsil-derived mesenchymal stem cells. Having a protein profile different from those of mesenchymal stem cells derived from other tissues or conditioned media thereof, the composition of the present invention exhibits inhibitory activity against EMT to suppress cancer metastasis, such as cancer cell motility and penetration, at the early stage and to induce the apoptosis of cancer cells. Thus, the composition has excellent effects of inhibiting cancer metastasis and preventing, alleviating, and treating cancer.

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Номер записи: 13
08-07-2015 дата публикации

ANTI-WRS MONOCLONAL ANTIBODY AND USES THEREOF

Номер: KR1020150077891A
Автор: KIM, SUNG HOON, CHOI, YON SIK, SHIM, HYUN BO, LEE, NAM JU, PARK, MIN HWA
Принадлежит:

The present invention relates to a tryptophanyl-tRNA synthetase antibody selectively bonding to WRS, and to a use of the same and, more specifically, to an antibody bonding to human WRS or a segment of the same, a production method thereof, and a composition for diagnosing cancer or self-immune diseases and inflammatory diseases including the same. The antibody or the segment thereof of the present invention specifically bonds to human WRS, and has no cross reactivity with other proteins, so that HRS detection and control are available, thereby being used for diagnosis of cancer or self-immune diseases and inflammatory diseases which are diseases relating to WRS. COPYRIGHT KIPO 2015 ...

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Номер записи: 14
08-07-2015 дата публикации

ANTI-KRS MONOCLONAL ANTIBODY AND USES THEREOF

Номер: KR1020150079476A
Автор: KIM, SUNG HOON, CHOI, YON SIK, SHIM, HYUN BO, LEE, NAM JU, PARK, MIN HWA
Принадлежит:

The present invention relates to a lysyl-tRNA synthetase antibody selectively bonding to KRS, and to a use of the same and, more specifically, to an antibody bonding to human KRS or a segment of the same, a production method thereof, and a composition for diagnosing cancer or self-immune diseases and inflammatory diseases including the same. The antibody or the segment thereof of the present invention specifically bonds to human KRS, and has no cross reactivity with other proteins, so that HRS detection and control are available, thereby being used for diagnosis of cancer or self-immune diseases and inflammatory diseases which are diseases relating to KRS. COPYRIGHT KIPO 2015 ...

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Номер записи: 15
12-12-2019 дата публикации

COMPOSITION, COMPRISING TONSIL-DERIVED MESENCHYMAL STEM CELL-CONTROLLING MEDIUM, FOR PREVENTION OR TREATMENT OF GRAFT-VERSUS-HOST DISEASE

Номер: WO2019235789A1
Автор: RYU, Kyung Ha, WOO, So Youn, PARK, Min Hwa, CHO, Kyung Ah, KIM, Han Su, KIM, Yu Hee, PARK, Joo Won
Принадлежит:

The present invention provides a composition, comprising a tonsil-derived mesenchymal stem cell-controlling medium, for prevention, alleviation, or treatment of graft-versus-host disease. The composition according to the present invention comprises various immunomodulators to suppress the migration or immune responses of grafted lymphocytes, thereby showing excellent preventive and therapeutic effects on graft-versus-host disease.

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Номер записи: 16
22-09-2016 дата публикации

항 KRS 모노클로날 항체 및 이의 용도

Номер: KR0101658625B1
Автор: 김성훈, 최연식, 심현보, 이남주, 박민화
Принадлежит: 재단법인 의약바이오컨버젼스연구단, 이화여자대학교 산학협력단

... 본 발명은 KRS(Lysyl-tRNA synthetase)에 선택적으로 결합하는 항 KRS 항체 및 이의 용도에 관한 것으로 보다 구체적으로는 인간 KRS에 결합하는 항체 또는 그 단편, 이의 생산방법 및 이를 포함하는 암 또는 자가면역질환 및 염증성질환 진단용 조성물에 관한 것이다. 본 발명의 항체 또는 그 단편은 인간 KRS에 특이적으로 결합하며, 동일한 ARS family를 포함한 다른 단백질과 교차반응성이 없어 KRS 검출 및 억제가 가능하므로 KRS 검출 및 KRS가 관련된 질환인 암 또는 자가면역질환 및 염증성질환의 진단 목적으로 사용될 수 있다.

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Номер записи: 17
03-10-2019 дата публикации

COMPOSITION, COMPRISING TONSIL-DERIVED MESENCHYMAL STEM CELL-CONTROLLING MEDIUM, FOR PREVENTION OR TREATMENT OF HEPATIC DISEASE

Номер: WO2019190218A1
Автор: RYU, Kyung Ha, WOO, So Youn, PARK, Joo Won, JO, In Ho, KIM, Han Su, CHO, Kyung Ah, KIM, Yu Hee, PARK, Min Hwa
Принадлежит:

The present invention relates to a composition comprising a tonsil-derived mesenchymal stem cell-controlling medium as an effective ingredient for prevention, alleviation, or treatment of hepatic diseases. The composition for prevention, alleviation, or treatment of hepatic diseases of the present invention exhibits different profiles for immunoregulatory elements and hepatic fibrosis inhibiting elements in the controlling medium in contrast with controlling media of mesenchymal stem cells derived from other tissues and, as a result, has excellent effects on the prevention, alleviation, and treatment of hepatic diseases.

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Номер записи: 18
16-10-2017 дата публикации

COMPOSITION FOR PREVENTING OR TREATING OF OSTEOPOROSIS COMPRISING TONSIL-DERIVED MESENCHYMAL STEM CELLS OR REGULATED MEDIUM THEREOF

Номер: KR1020170115009A
Автор: KIM, YU HEE, RYU, KYUNG HA, WOO, SO YOUN, CHO, KYUNG AH, PARK, MIN HWA
Принадлежит:

The present invention relates to a pharmaceutical composition for preventing or treating osteoporosis and visceral obesity, comprising tonsil-derived mesenchymal stem cells, a regulated medium thereof, or both as an active ingredient. The pharmaceutical composition of the present invention shows remarkable prevention and treatment effects on osteoporosis and/or visceral obesity by promoting osteoblast differentiation, adipocyte differentiation inhibition, bone marrow fat reduction, visceral fat accumulation inhibition, and weight loss effects. COPYRIGHT KIPO 2017 ...

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Номер записи: 19
08-07-2015 дата публикации

ANTI-NRS MONOCLONAL ANTIBODY AND USES THEREOF

Номер: KR1020150077887A
Автор: KIM, SUNG HOON, CHOI, YON SIK, SHIM, HYUN BO, LEE, NAM JU, PARK, MIN HWA
Принадлежит:

The present invention relates to an anti-asparaginyl-tRNA synthetase (NRS) antibody selectively coupling with NRS and a use of the same and, more specifically, to an antibody coupling with human NRS or a segment of the same, a production method thereof, and a composition for diagnosing self-immune diseases and inflammatory diseases including the same. The antibody or segment thereof of the present invention specifically bonds to human NRS, and does not have cross reactivity with other proteins, so that detection and control of NRS is available, thereby being used for NRS detection and diagnosis of self-immune diseases and inflammatory diseases relating to NRS. COPYRIGHT KIPO 2015 ...

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Номер записи: 20
14-12-2022 дата публикации

플라즈마 방전기술을 이용한 축산물 및 가공장 위생 안전성 향상 처리방법

Номер: KR102477468B1
Автор: 이승제, 정은선, 윤나래, 박민화
Принадлежит: 재단법인 전남바이오산업진흥원

... 본 발명은 플라즈마 방전기술을 이용한 축산물 및 가공장 위생 안전성 향상 처리방법에 관한 것으로, 본 발명에 따르면, 축산물의 위생 안전성을 향상시키기 위해 플라즈마 방전기술을 이용하는 처리방법에 있어서, 플라즈마수 장치를 이용하여 축산물 또는 가공장에 플라즈마수를 분무하는 플라즈마수 처리단계를 포함하는 축산물 및 가공장 위생 안전성 향상 처리방법을 제공할 수 있다.

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Номер записи: 21
21-09-2016 дата публикации

COMPOSITION FOR PREVENTING OR TREATING IMMUNOLOGICAL DISEASE

Номер: KR1020160109358A
Автор: RYU, KYUNG HA, RYU, JUNG HWA, WOO, SO YOUN, KIM, YU HEE, PARK, MIN HWA, JO, IN HO
Принадлежит:

The present invention relates to a pharmaceutical composition for preventing or treating immunological disease, containing a tonsil-derived mesenchymal stem cells (T-MSCs) as an active ingredient. The pharmaceutical composition for preventing and treating immunological disease suppresses differentiation and maturation of dendritic cell, inhibits secretion of immune reaction-inducing cytokines secreted by dendritic cell, and weakens functions of dendritic cell-mediated T lymphocytes, thereby regulating an immune reaction. Thus, the pharmaceutical composition shows remarkable effects of preventing and treating immunological disease. COPYRIGHT KIPO 2016 ...

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Номер записи: 22