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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 26. Отображено 26.
12-05-2016 дата публикации

QUANTITATIVE ANALYTIC METHOD FOR LEAD OR ARSENIC

Номер: KR1020160052185A
Принадлежит:

The present invention relates to a quantitative analytic method for lead or arsenic, comprising: a step of preparing a nitric acid solution serving as a blank liquid standard sample; a step of preparing two or more liquid standard samples with different concentrations of lead or arsenic by adding different amounts of lead or arsenic to predetermined volumes of a nitric acid solution; a step of determining an interfering element by irradiating analysis samples with an X-ray and by selecting an interfering element having an energy value within a range of energy values of lead or arsenic, among the detected elements; a deconvolution step of correcting a detected energy peak of lead or arsenic, among detected energy peaks detected by irradiating the liquid standard samples with different concentrations with the X-ray in the determining of the interfering element, with a repeatedly detected energy peak of the interfering element; a step of drawing a standard calibration curve by performing the ...

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16-01-2019 дата публикации

단핵식세포계 세포의 AGE-알부민 합성 또는 분비 저해제를 유효성분으로 포함하는 허혈성 심장질환 예방 또는 치료용 조성물

Номер: KR0101939401B1
Автор: 이봉희, 변경희
Принадлежит: 가천대학교 산학협력단

... 본 발명은 허혈성 심장질환의 발병시에 심근세포의 세포사를 유도하는 단핵식세포계 세포의 AGE-알부민 합성 또는 분비를 저해하는 저해제를 유효성분으로 포함하는 허혈성 심장질환 예방 또는 치료용 약학 조성물 및 상기 저해제의 스크리닝 방법에 관한 것이다. 본 발명의 허혈성 심장질환 예방 또는 치료용 약학 조성물은 단핵식세포계 세포의 AGE-알부민 합성 또는 분비 저해제를 유효성분으로 포함하여, AGE-알부민으로부터 유도된 세포사를 억제 또는 감소시킬 수 있으므로, 심근경색을 비롯한 다양한 허혈성 심장질환의 예방 또는 치료에 널리 활용될 수 있을 것이다.

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21-02-2018 дата публикации

METHOD FOR DETERMINING IDENTITY OF COSMETIC COMPOSITIONS

Номер: KR1020180017467A
Принадлежит:

In the present specification, provided is a method for distinguishing a genuine product and a counterfeit product in a cosmetic composition without a sample preprocess. Specifically, the identity can be determined by comparing spectra of components derived by using at least two or more among an atmospheric solid analysis probe (ASAP), an ion mobility separation (IMS) apparatus, and a time of flight mass spectrometer (TOF-MS). COPYRIGHT KIPO 2018 ...

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27-09-2016 дата публикации

METHOD FOR PERFORMING ACCELERATED STABILITY TEST ON ACTIVE INGREDIENT INCLUDED IN ORAL CLEANING COMPOSITION

Номер: KR1020160111619A
Принадлежит:

The present invention relates to a novel method for performing an accelerated test capable of remarkably reduce a stability test period with respect to an active ingredient included in an oral cleaning composition. According to the method for performing an accelerated test of the present invention, an optimal condition for performing an accelerated test is induced, and an accelerated stability test is performed under the induced optimal condition for performing an accelerated test. According to the present invention, when a stability test is performed on an active ingredient included in an oral cleaning composition, a test period is remarkably reduced compared to conventional stability test, so production efficiency can be remarkably improved and a prescription content standard of an active ingredient in a product composition can be established. For instance, when a stability test of tocopherol acetate is performed according to the present invention, a test period can be reduced to 20 days ...

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26-10-2012 дата публикации

DIAGNOSTIC AND THERAPEUTIC METHOD FOR GLIOMA THROUGH IDENTIFICATION OF PROTEIN RELOCATION

Номер: WO2012144871A2
Принадлежит:

The present invention relates to a method for diagnosing glioma by comparing the location of protein of an individual to be diagnosed with the control group of normal neurocytes. More specifically, the invention relates to a diagnostic method for glioma comprising a step of determining if an individual has glioma when an expression rate in endoplasmic reticulum of GFRα4 is higher than that in a cell membrane, and a method for screening a therapeutic agent for glioma. The diagnostic method of the invention can accurately diagnose glioma by comparing expression rates at specific intracellular locations of a protein and also diagnose the progress of glioma.

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08-03-2012 дата публикации

NOVEL COMPOUND ACTING AS A CANNABINOID RECEPTOR-1 INHIBITOR

Номер: WO2012030170A3
Принадлежит:

Disclosed are a novel compound acting as a cannabinoid receptor-1 inhibitor, a prodrug thereof, a pharmaceutically acceptable salt thereof, and a hydrate thereof or a solvate thereof. The novel compound or the like is useful for preventing or treating diseases mediated by cannabinoid receptor-1.

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15-10-2015 дата публикации

A Role and Use of RXRα related to mitochondrial retrograde signaling pathways

Номер: KR0101556439B1
Принадлежит: 서울대학교산학협력단

... 본 발명은 미토콘드리아 tRNALeu에서의 A3243G 변이(mt3243)에 따른 미토콘드리아 역행성 신호 경로에 대한 RXRα(retinoid X receptor alpha)의 연관성에 관한 것으로, 보다 구체적으로 미토콘드리아 mt3243 변이에 의해 미토콘드리아 기능 이상이 생기는 기전에 있어서의 RXRα-PGC1a 상호작용 및 이에 따른 분자적 메커니즘을 이용하는 다양한 용도에 관한 것이다.

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12-05-2016 дата публикации

QUANTITATIVE ANALYSIS METHOD OF LEAD OR ARSENIC

Номер: KR1020160052187A
Принадлежит:

The present invention relates to a quantitative analysis method of lead or arsenic comprising the steps of: preparing talcum powder, which is the standard sample of blank powder; preparing two or more standard samples of powder for each concentration, which have different concentrations, by adding lead or arsenic to the talcum powder; selecting an interference element having an energy value corresponding to the range of the detected energy value of lead or arsenic among element detected by irradiating a sample for analysis with x-rays; correcting the detected energy peak of lead or arsenic among energy peaks, which have been detected by irradiating the standard samples of powder for each concentration with x-rays in the step of selecting the interference element, from the overlapping detected energy peak of the interference element using a deconvolution method; drawing a standard calibration line by conducting the deconvolution method after irradiating the prepared standard samples for ...

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12-05-2016 дата публикации

QUANTITATIVE ANALYTIC METHOD FOR ANTIMON OR CADMIUM

Номер: KR1020160052186A
Принадлежит:

The present invention relates to a quantitative analytic method for antimon or cadmium comprising: a step of preparing a nitric acid solution which is a bland liquid reference specimen; a step of preparing at least two liquid reference specimens of which a concentration is different by adding antimon or cadmium to the nitric acid solution; a step of selecting an interference element of which a corresponding energy value is within an anitmon or cadmium detecting energy value range among elements detected by radiating X-rays to the analysis specimen; a deconvolution step of correcting an antimom or cadmium detecting energy peak among energy peaks detected in the step of selecting the interference element by radiating the X-rays to the liquid reference specimens with different concentrations from a detected energy peak of the overlapped interference element; a step of preparing a reference calibration curve by performing the deconvolution step after radiating the X-rays to the prepared liquid ...

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26-10-2012 дата публикации

DIAGNOSTIC AND THERAPEUTIC METHOD FOR GLIOMA THROUGH IDENTIFICATION OF PROTEIN RELOCATION

Номер: WO2012144871A3
Принадлежит:

The present invention relates to a method for diagnosing glioma by comparing the location of protein of an individual to be diagnosed with the control group of normal neurocytes. More specifically, the invention relates to a diagnostic method for glioma comprising a step of determining if an individual has glioma when an expression rate in endoplasmic reticulum of GFRα4 is higher than that in a cell membrane, and a method for screening a therapeutic agent for glioma. The diagnostic method of the invention can accurately diagnose glioma by comparing expression rates at specific intracellular locations of a protein and also diagnose the progress of glioma.

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17-11-2011 дата публикации

METHOD FOR INHIBITING THE INDUCTION OF CELL DEATH BY INHIBITING THE SYNTHESIS OR SECRETION OF AGE-ALBUMIN IN CELLS OF THE MONONUCLEAR PHAGOCYTE SYSTEM

Номер: WO2011142545A3
Принадлежит:

The present invention relates to a method for inhibiting the induction of cell death by inhibiting the synthesis or secretion of AGE-albumin in cells of the mononuclear phagocyte system, to an AGE-albumin synthesis inhibitor, and to a pharmaceutical composition comprising the AGE-albumin synthesis inhibitor for preventing or treating degenerative disease and autoimmune disease. The AGE-albumin of the present invention is synthesized and secreted in human microglia or human macrophages in an Alzheimer's model, stroke model, Parkinson's disease model and rheumatoid arthritis model. The AGE-albumin synthesis and secretion are caused by oxidative stress. The expression of RAGE increases in first-order human neurons or cartilage cells to which AGE-albumin is administered, whereupon a MAPK signaling pathway is activated and the expression of Bax increases to induce an increase in calcium in mitochondria, thus finally inducing cell death. Therefore, the AGE-albumin synthesis inhibitor of the present ...

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12-05-2016 дата публикации

QUANTITATIVE ANALYTIC METHOD FOR ANTIMON OR CADMIUM

Номер: KR1020160052188A
Принадлежит:

The present invention relates to a quantitative analytic method for antimon or cadmium comprising: a step of preparing a talc powder which is a blank powder reference specimen; a step of preparing at least two powder referenced specimens with different concentrations by adding antimon or cadmium to the talc powder; a step of selecting an interference element of which a corresponding energy value is within the anitmon or cadmium detecting an energy value range among the elements detected by radiating X-rays to the analysis specimen; a deconvolution step of correcting the antimom or cadmium detecting energy peak among energy peaks detected in the step of selecting the interference element by radiating the X-rays to the liquid reference specimens with different concentrations from a detected energy peak of the overlapped interference element; a step of preparing a reference calibration curve by performing the deconvolution step after radiating the X-rays to the prepared liquid reference specimens ...

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01-11-2018 дата публикации

PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF ALZHEIMER'S DISEASE, COMPRISING STEM CELL SECRETING SRAGE

Номер: WO2018199662A1
Принадлежит:

Provided are stem cells secreting soluble RAGE and a medicinal use thereof in preventing and/or treating Alzheimer's disease.

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02-11-2018 дата публикации

카나비노이드 1 수용체 저해제로 작용하는 신규 화합물

Номер: KR0101914161B1
Принадлежит: (주)아모레퍼시픽

... 본 발명은 카나비노이드 1 수용체 저해제로 작용하는 신규 화합물, 이의 프로드럭, 이의 약학적으로 허용 가능한 염, 이의 수화물 또는 이의 용매화물을 개시한다. 상기 신규 화합물 등은 카나비노이드 1 수용체 매개 질환의 예방 또는 치료용으로 유용하다.

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29-09-2016 дата публикации

ORAL COMPOSITION EFFECTIVE IN INHIBITING CALCULUS FORMATION

Номер: WO2016153144A1
Принадлежит:

The present invention relates to an oral composition for inhibiting calculus formation, containing an anionic sequestering agent and a cationic polymer and, more specifically, to an oral composition in which a phosphate-based anionic sequestering agent and a polyquaternium-based cationic polymer form a coacervate during teeth brushing such that the coacervate adheres to the surface of the teeth, thereby allowing the anionic sequestering agent, which is an ingredient inhibiting calculus formation, to remain in the mouth for a long time even after rinsing. The oral composition for inhibiting calculus formation, of the present invention, can effectively prevent calculus formation on the surface of teeth and can simultaneously improve foaming power while maintaining the flavor of a toothpaste.

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16-05-2013 дата публикации

COMPOSITION FOR PREVENTING OR TREATING ISCHAEMIC HEART DISEASE COMPRISING, AS AN ACTIVE INGREDIENT, AGE-ALBUMIN SYNTHESIS OR SECRETION INHIBITOR FOR MONONUCLEAR PHAGOCYTE SYSTEM CELLS

Номер: WO2013070048A1
Принадлежит:

The present invention relates to a pharmaceutical composition for preventing or treating ischaemic heart disease comprising, as an active ingredient, an inhibitor that inhibits AGE-albumin synthesis or secretion in mononuclear phagocyte system cells whereby apoptosis is induced in myocardial cells following the onset of ischaemic heart disease, and the present invention also relates to a screening method for the inhibitor. The pharmaceutical composition for preventing or treating ischaemic heart disease of the present invention can be widely used to prevent or treat various forms of ischaemic heart disease and notably myocardial infarction because the pharmaceutical composition comprises, as an active ingredient, an AGE-albumin synthesis or secretion inhibitor for mononuclear phagocyte system cells and the pharmaceutical composition can therefore inhibit or reduce apoptosis induced from AGE-albumin.

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11-01-2019 дата публикации

피로갈롤-플로로글루시놀-6,6'바이엑콜(PPB)을 유효성분으로 함유하는 대사질환, 혈관계 질환, 또는 혈전성 질환의 예방 또는 치료용 조성물

Номер: KR0101936926B1

... 본 발명은 피로갈롤-플로로글루시놀-6,6'바이엑콜(PPB)을 유효성분으로 함유하는 대사질환, 혈관계 질환, 또는 혈전성 질환의 예방 또는 치료용 조성물에 관한 것으로, 본 발명에 따른 감태 유래 PPB는 세포단위의 실험과, 질환 유도 동물 모델 실험으로부터 항비만 효과, 혈관 내피 보호 효과, 및 혈액 응고 방지 효과를 확인한 바, 천연물 유래의 피로갈롤-플로로글루시놀-6,6'바이엑콜(PPB)을 유효성분으로 함유하는, 대사 질환 또는 혈관계 질환, 또는 혈전성 질환의 예방, 개선 또는 치료용 약학적 조성물 및 건강기능식품 조성물이 제공될 수 있는 유용한 효과가 있다.

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28-09-2016 дата публикации

ORAL COMPOSITION FOR EFFECTIVELY INHIBITING PLAQUE FORMATION

Номер: KR1020160112919A
Принадлежит:

The present invention relates to an oral composition for inhibiting the formation of dental plaque, which comprises a cationic polymer and an anionic metal ion blocking agent. More specifically, the present invention relates to an oral composition, which enables a phosphate-based anion metal ion blocking agent and a polyquaternium-based cation polymer to form coacervate during the process of tooth brushing. The oral composition is attached to the surface of teeth, and enables the anion-based metal ion blocking agent as an ingredient of inhibiting the formation of dental plaque to be remained in the oral cavity after washing the same for a long period of time. The oral composition for inhibiting the formation of dental plaque can prevent the formation of dental plaque on the surface of the teeth in an effective manner, and can improve the foaming power while maintaining the smell and the taste of the toothpaste. COPYRIGHT KIPO 2016 ...

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08-03-2012 дата публикации

NOVEL COMPOUND ACTING AS A CANNABINOID RECEPTOR-1 INHIBITOR

Номер: KR2012030170A2
Принадлежит:

Disclosed are a novel compound acting as a cannabinoid receptor-1 inhibitor, a prodrug thereof, a pharmaceutically acceptable salt thereof, and a hydrate thereof or a solvate thereof. The novel compound or the like is useful for preventing or treating diseases mediated by cannabinoid receptor-1.

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27-12-2017 дата публикации

SIMULTANEOUS ANALYSIS METHOD FOR ULTRAVIOLET BLOCKING COMPONENTS

Номер: KR1020170141935A
Принадлежит:

The present invention relates to a simultaneous analysis method for ultraviolet blocking components showing each of different chemical properties. More specifically, the present invention relates to a simultaneous analysis method enabling a simultaneous analysis on hydrophilic and lyphophilic ultraviolet blocking components existing in cosmetic ingredients in a quick and accurate way, by means of supercritical fluid chromatography (SFC). COPYRIGHT KIPO 2018 ...

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19-12-2017 дата публикации

프라그 억제용 구강조성물

Номер: KR0101810140B1
Принадлежит: (주)아모레퍼시픽

... 본 발명은 프라그 억제용 구강조성물에 관한 것이다. 본 발명의 구강조성물은 프라그 억제능을 가지는 유효성분이 치아 표면에 장시간 잔류하여, 바이오 필름의 생성을 억제함에 따라 프라그 생성을 억제하므로 잇몸질환을 예방하는데 유용하다. 특히 본 발명의 구강 조성물은 알긴산 또는 알긴산염이 치아 흡착 물질로 작용하여 양이온 항균제가 치아 표면으로 잘 전달되고, 세정시에도 치아 표면에 남아서 항균력을 지속시킬 수 있어서 유용하다.

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27-04-2017 дата публикации

METHOD FOR SELECTIVELY PRODUCING GINSENOSIDE F2, COMPOUND MC, AND COMPOUND O FROM SAPONINS OF GINSENG THROUGH ENZYMATIC METHOD

Номер: WO2017069561A1
Принадлежит:

The present invention relates to a method for selectively producing ginsenoside F2, compound Mc, and compound O, which is originally present in ginseng in trace amounts, from saponins of ginseng and, more specifically, to a method capable of obtaining desired target compounds, that is, ginsenoside F2, compound Mc, and compound O, in high yields, by treating saponins, obtained from ginseng, with particular enzymes to structurally convert the saponins.

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17-11-2011 дата публикации

METHOD FOR INHIBITING THE INDUCTION OF CELL DEATH BY INHIBITING THE SYNTHESIS OR SECRETION OF AGE-ALBUMIN IN CELLS OF THE MONONUCLEAR PHAGOCYTE SYSTEM

Номер: WO2011142545A2
Принадлежит:

The present invention relates to a method for inhibiting the induction of cell death by inhibiting the synthesis or secretion of AGE-albumin in cells of the mononuclear phagocyte system, to an AGE-albumin synthesis inhibitor, and to a pharmaceutical composition comprising the AGE-albumin synthesis inhibitor for preventing or treating degenerative disease and autoimmune disease. The AGE-albumin of the present invention is synthesized and secreted in human microglia or human macrophages in an Alzheimer's model, stroke model, Parkinson's disease model and rheumatoid arthritis model. The AGE-albumin synthesis and secretion are caused by oxidative stress. The expression of RAGE increases in first-order human neurons or cartilage cells to which AGE-albumin is administered, whereupon a MAPK signaling pathway is activated and the expression of Bax increases to induce an increase in calcium in mitochondria, thus finally inducing cell death. Therefore, the AGE-albumin synthesis inhibitor of the present ...

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26-08-2015 дата публикации

ORAL COMPOSITION FOR INHIBITING DENTAL PLAQUE

Номер: KR1020150097452A
Принадлежит:

The present invention relates to an oral composition for inhibiting dental plaque. The oral composition of the present invention inhibits generation of a bio film and thereby, inhibits generation of plaque as an active ingredient having a plaque inhibition effect remains on the tooth surface for a long time. Therefore, the present invention is useful for prevention of a periodontal disease. In particular, the oral composition of the present invention contains alginic acid or alginate acting as a tooth adsorption material and thereby, a cationic antibacterial agent is efficiently delivered to the tooth surface and therefore, is very useful as the antibacterial effect remains on the tooth surface even in cleaning. COPYRIGHT KIPO 2015 ...

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04-05-2017 дата публикации

METHOD FOR SELECTIVELY PREPARING GINSENOSIDE F2, COMPOUND MC AND COMPOUND O FROM SAPONIN OF GINSENG BY ENZYMATIC METHOD

Номер: KR1020170047007A
Принадлежит:

The present invention relates to a method for selectively preparing ginsenoside F2, compound Mc and compound O, which originally exist in ginseng at low levels, from saponin of ginseng, and specifically, to a method for obtaining desired and targeted compound, in other words, ginsenoside F2, compound Mc and compound O with a high yield, by treating a specific enzyme to saponin obtained from ginseng and structure converting the saponin. COPYRIGHT KIPO 2017 ...

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11-01-2019 дата публикации

감태 추출물, 이의 제조방법 및 이를 유효성분으로 함유하는 혈관계 질환의 예방 또는 치료용 약학적 조성물

Номер: KR0101936930B1

... 본 발명은 감태 추출물, 이의 제조방법 및 이를 유효성분으로 함유하는 혈관계 질환의 예방 또는 치료용 약학적 조성물에 관한 것으로, 본 발명에 따른 감태(Ecklonia cava) 추출물은 혈관계 질환을 야기할 수 있는 인자에 대하여, 세포 단위 실험 및 질환 유도 동물 모델 실험을 통해 약효가 있음을 확인한 바, 본 발명에서는 감태 추출물을 유효성분으로 함유하는, 혈관계 질환의 예방, 개선 또는 치료용 약학적 조성물 및 건강기능식품 조성물이 제공될 수 있는 유용한 효과가 있다.

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