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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 16. Отображено 16.
22-06-2018 дата публикации

NOVEL THIOSULFATE DERIVATIVE, PREPARATION METHOD THEREOF, AND COSMETIC COMPOSITION COMPRISING SAME

Номер: KR1020180068694A
Автор: PARK, YOUNG JUN, SONG, HYUN NAM, KIM, HYEONG MI, KIM, KYEONG HU, MOON, WON KANG, MOON, SUNG HO, PARK, SEON KYUNG, LEE, MIN SUP, LIM, JOO HYUCK
Принадлежит:

The present invention provides a novel thiosulfate derivative, a preparation method thereof, and a cosmetic composition comprising the same as an effective component. The thiosulfate derivative of the present invention has an effect of suppressing melanin formation and a whitening effect by the inhibition of tyrosinase activity, and thus can be used for a cosmetic composition. COPYRIGHT KIPO 2018 (AA) Melanin production (%) versus negative control group (BB) Negative control group (CC) Positive control group (DD) Example 2 ...

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Номер записи: 1
25-02-2016 дата публикации

Antibody-Linker-Drug Conjugates, Process for Preparing the Same and Anti-cancer Agents Comprising the Same

Номер: KR0101597100B1
Автор: 박영준, 정진교, 최영미, 이민섭, 조유영, 김연정, 최준헌, 이진서, 조은주, 송현남, 박성준, 이종협, 이상엽, 이인숙, 김준우, 홍승서
Принадлежит: (주)셀트리온

... 본 발명은 항체의 라이신 잔기에 직접 결합할 수 있는 효소-분해형 펩타이드 링커를 통해 항체와 세포독성 약물이 접합된 항체-링커-약물 결합체, 그의 제조방법 및 그를 유효성분으로 포함하는 항암제 조성물을 제공한다.

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Номер записи: 2
30-08-2018 дата публикации

NOVEL FLAVONOID DERIVATIVE, PREPARATION METHOD THEREOF, AND COMPOSITION CONTAINING NOVEL FLAVONOID DERIVATIVE

Номер: KR1020180097044A
Автор: PARK, YOUNG JUN, KIM, HYEONG MI, LEE, JIN SEO, SONG, HYUN NAM, MOON, WON KANG, KIM, KYEONG HU, PARK, SEON KYUNG, LEE, SEUNG KI, LIM, JOO HYUCK, LEE, MIN SUP
Принадлежит:

The present invention relates to a novel flavonoid derivative, a preparation method thereof, and a cosmetic composition or a composition for external application for skin containing the novel flavonoid derivative as an active ingredient. The novel flavonoid derivative provides excellent skin whitening and skin irritation mitigating effects. COPYRIGHT KIPO 2018 (AA) Melanin production relative to negative control group (%) (BB) Negative control group (CC) Positive control group (DD) Example 1 ...

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Номер записи: 3
27-03-2014 дата публикации

DOLASTATIN-10 DERIVATIVE, METHOD OF PRODUCING SAME AND ANTICANCER DRUG COMPOSITION CONTAINING SAME

Номер: WO2014046441A1
Автор: PARK, Young Jun, JEONG, Jin-kyo, CHOI, Young Mi, LEE, Min Seob, CHOI, Joon hun, CHO, Eun Joo, SONG, Hyunnam, PARK, Sung Jun, LEE, Jong-hyoup, HONG, Seung Suh
Принадлежит:

The present invention provides a dolastatin-10 derivative having excellent anticancer activity, a method of producing the same and anticancer drug composition containing the same as an active principle.

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Номер записи: 4
25-02-2016 дата публикации

Antibody-Linker-Drug Conjugates, Process for Preparing the Same and Anti-cancer Agents Comprising the Same

Номер: KR0101597110B1
Автор: 박영준, 정진교, 최영미, 이민섭, 최준헌, 이진서, 조은주, 송현남, 박성준, 이종협, 이상엽, 이인숙, 김준우, 홍승서, 김연정, 김경석
Принадлежит: (주)셀트리온

... 본 발명은 항체의 라이신 잔기에 직접 결합할 수 있는 효소-분해형 펩타이드 링커를 통해 항체와 세포독성 약물이 접합된 항체-링커-약물 결합체, 그의 제조방법 및 그를 유효성분으로 포함하는 항암제 조성물을 제공한다.

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Номер записи: 5
29-08-2016 дата публикации

펩타이드가 결합된 안정한 아스코르빈산 유도체, 그의 제조방법 및 그를 포함하는 화장료 조성물

Номер: KR0101652204B1
Автор: 박영준, 김정윤, 정진교, 김형미, 조은주, 임주혁, 송현남, 박선경, 문원강, 장신재, 홍승서
Принадлежит: (주)셀트리온

... 본 발명은 펩타이드가 결합된 안정한 아스코르빈산 유도체, 그의 제조방법 및 그를 유효성분으로 포함하는 화장료 조성물을 제공한다. 본 발명의 펩타이드가 결합된 아스코르빈산 유도체는 멜라닌 생성 억제를 통한 미백 효과 및 콜라겐 생성 활성화를 통한 주름개선 효과를 동시에 나타내는 이중복합 기능을 가지며, 화장료 조성물에 사용될 수 있다.

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Номер записи: 6
13-03-2017 дата публикации

FATTY ACID-ATTACHED TRIPEPTIDE AND COSMETIC COMPOSITION FOR AMELIORATING WRINKLES CONTAINING SAME

Номер: KR101715599B1
Автор: PARK, YOUNG JUN, MOON, WON KANG, PARK, SUNG JUN, SONG, HYUN NAM, LEE, JIN SEO, PARK, SEON KYUNG, LEE, MIN SUP, MOO, SUNG HO, LEE, SEUNG KI, KIM, JONG MOOK, KIM, JUNG YUN, KIM, JU YEON, CHOI, CHI HO
Принадлежит: CELLTRION, INC.

The present invention relates to fatty acid-attached tripeptide, and a cosmetic composition containing the same, ensuring excellent effects such as skin antiaging effects, wrinkle ameliorating effects, skin elasticity improving effects, and skin infiltrating effects. COPYRIGHT KIPO 2017 ...

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Номер записи: 7
02-06-2016 дата публикации

STABLE PEPTIDE-CONJUGATED ASCORBIC ACID DERIVATIVE, METHOD FOR PREPARING SAME, AND COSMETIC COMPOSITION CONTAINING SAME

Номер: WO2016085127A2
Автор: PARK, Young Jun, KIM, Jung Yun, JEONG, Jin Kyo, KIM, Hyeong Mi, CHO, Eun Joo, LIM, Joo Hyuck, SONG, Hyun Nam, PARK, Seon Kyung, MOON, Won Kang, CHANG, Shin Jae, HONG, Seung Suh
Принадлежит:

The present invention provides a stable peptide-conjugated ascorbic acid derivative, a method for preparing the same, and a cosmetic composition containing the same as an active ingredient. The peptide-conjugated ascorbic acid derivative of the present invention has a dual complex function of exhibiting a whitening effect through melanogenesis inhibition and a wrinkle reduction effect through collagenesis activation at the same time, and can be used for a cosmetic composition.

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Номер записи: 8
25-02-2016 дата публикации

Antibody-Linker-Drug Conjugates, Process for Preparing the Same and Anti-cancer Agents Comprising the Same

Номер: KR0101597105B1
Автор: 박영준, 정진교, 최영미, 이민섭, 최준헌, 이진서, 조은주, 송현남, 박성준, 이종협, 이상엽, 이인숙, 김준우, 홍승서, 김연정, 김경석
Принадлежит: (주)셀트리온

... 본 발명은 항체의 라이신 잔기에 직접 결합할 수 있는 효소-분해형 펩타이드 링커를 통해 항체와 세포독성 약물이 접합된 항체-링커-약물 결합체, 그의 제조방법 및 그를 유효성분으로 포함하는 항암제 조성물을 제공한다.

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Номер записи: 9
25-02-2016 дата публикации

Antibody-Linker-Drug Conjugates, Process for Preparing the Same and Anti-cancer Agents Comprising the Same

Номер: KR0101597101B1
Автор: 박영준, 정진교, 최영미, 이민섭, 최준헌, 이진서, 조은주, 송현남, 박성준, 이종협, 이상엽, 이인숙, 김준우, 홍승서, 김연정, 김경석
Принадлежит: (주)셀트리온

... 본 발명은 항체의 라이신 잔기에 직접 결합할 수 있는 효소-분해형 펩타이드 링커를 통해 항체와 세포독성 약물이 접합된 항체-링커-약물 결합체, 그의 제조방법 및 그를 유효성분으로 포함하는 항암제 조성물을 제공한다.

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Номер записи: 10
12-04-2018 дата публикации

TRIPEPTIDE HAVING FATTY ACIDS BONDED THERETO, AND ANTI-WRINKLE COSMETIC COMPOSITION COMPRISING SAME

Номер: WO2018066914A1
Автор: PARK, Young Jun, MOON, Won Kang, PARK, Sung Jun, SONG, Hyun Nam, LEE, Jin Seo, PARK, Seon Kyung, LEE, Min Sup, MOON, Sung Ho, LEE, Seung Ki, KIM, Jong Mook, KIM, Jung Yun, KIM, Ju Yeon, CHOI, Chi Ho
Принадлежит:

The present invention relates to a tripeptide having fatty acids bonded thereto and a cosmetic composition comprising same and provides excellent skin anti-aging, wrinkle reduction, skin elasticity enhancement, and skin permeation effects.

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Номер записи: 11
10-07-2014 дата публикации

ANTIBODY-LINKER-DRUG CONJUGATE, PREPARATION METHOD THEREFOR, AND ANTICANCER DRUG COMPOSITION CONTAINING SAME

Номер: WO2014107024A1
Автор: PARK, Young Jun, JEONG, Jin-kyo, CHOI, Young Mi, LEE, Minseob, KIM, Yeon Jung, KIM, Kyoung Suk, CHOI, Joon hun, LEE, Jin Seo, CHO, Eun Joo, SONG, Hyunnam, PARK, Sung Jun, LEE, Jong-hyoup, LEE, Matthew Sangyup, LEE, In-Suk, KIM, Joon woo, HONG, Seung Suh
Принадлежит:

The present invention relates to an antibody-linker-drug conjugate in which an antibody and a cytotoxic drug are conjugated through an enzyme cleavable peptide linker capable of directly binding to a lysine residue of an antibody, a preparation method therefor, and an anticancer drug composition containing the same as an active ingredient.

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Номер записи: 12
02-06-2016 дата публикации

STABLE PEPTIDE-CONJUGATED ASCORBIC ACID DERIVATIVE, METHOD FOR PREPARING SAME, AND COSMETIC COMPOSITION CONTAINING SAME

Номер: WO2016085127A3
Автор: PARK, Young Jun, KIM, Jung Yun, JEONG, Jin Kyo, KIM, Hyeong Mi, CHO, Eun Joo, LIM, Joo Hyuck, SONG, Hyun Nam, PARK, Seon Kyung, MOON, Won Kang, CHANG, Shin Jae, HONG, Seung Suh
Принадлежит:

The present invention provides a stable peptide-conjugated ascorbic acid derivative, a method for preparing the same, and a cosmetic composition containing the same as an active ingredient. The peptide-conjugated ascorbic acid derivative of the present invention has a dual complex function of exhibiting a whitening effect through melanogenesis inhibition and a wrinkle reduction effect through collagenesis activation at the same time, and can be used for a cosmetic composition.

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Номер записи: 13
07-06-2016 дата публикации

STABLE PEPTIDE-CONJUGATED ASCORBIC ACID DERIVATIVE, PRODUCING METHOD THEREOF, AND COSMETIC COMPOSITION COMPRISING SAME

Номер: KR1020160063976A
Автор: PARK, YOUNG JUN, KIM, JUNG YUN, JEONG, JIN KYO, KIM, HYEONG MI, CHO, EUN JOO, LIM, JOO HYUCK, SONG, HYUN NAM, PARK, SEON KYUNG, MOON, WON KANG, CHANG, SHIN JAE, HONG, SEUNG SUH
Принадлежит:

The present invention provides a stable peptide-conjugated ascorbic acid derivative, a producing method thereof, and a cosmetic composition comprising the same as an active ingredient. The peptide-conjugated ascorbic acid derivative of the present invention has a dual complex function of exhibiting a whitening effect through melanogenesis inhibition and a wrinkle reduction effect through collagenesis activation at the same time, and can be used for a cosmetic composition. COPYRIGHT KIPO 2016 ...

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Номер записи: 14
06-12-2017 дата публикации

COMPOSITION COMPRISING STABILIZED ASCORBIC ACID DERIVATIVES BONDED WITH PEPTIDE FOR ALLEVIATING SKIN INFLAMMATION

Номер: KR1020170133845A
Автор: PARK, YOUNG JUN, JEONG, JIN KYO, CHO, EUN JOO, SONG, HYUN NAM, KIM, HYEONG MI, LIM, JOO HYUCK, MOON, SUNG HO, CHANG, SHIN JAE, MOON, WON KANG, PARK, SEON KYUNG
Принадлежит:

The present invention relates to a composition comprising stabilized ascorbic acid derivatives bonded with a peptide for alleviating skin inflammation, and the ascorbic acid derivatives bonded with a peptide in the present invention inhibits generation of NO and PGE2 to have an excellent effect of alleviating skin inflammation. COPYRIGHT KIPO 2017 ...

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Номер записи: 15
20-02-2019 дата публикации

약제학적 성질이 개선된 L-카르니틴 화합물의 염, 이의 제조방법, 이를 함유하는 약학 조성물

Номер: KR1020190017310A
Автор: 박영준, 송현남, 김준우, 유진
Принадлежит:

... 본 발명은 약제학적 성질이 개선된 L-카르니틴 화합물의 산 부가염, 이의 제조방법 및 이의 약학 조성물에 관한 것이다. 본 발명에 따른 L-카르니틴 화합물의 산 부가염은 우수한 용적밀도 또는/및 탭 밀도를 가지고 있어 제제공정 과정에서의 비용을 절감하여 생산성을 높일 수 있고, 약제학적 제형의 제조에 적합하다.

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Номер записи: 16