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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 18. Отображено 18.
17-02-2016 дата публикации

SYSTEM FOR CURING COLD WEATHER CONCRETE

Номер: KR0101594922B1
Автор: 양진, 김덕용
Принадлежит: (주)대호종합건설

... 한중콘크리트 양생 시스템에 관한 것으로서, 본 개시의 일 태양에 따르면(According to one aspect of the present disclosure), 한중콘크리트로 타설된 천정면; 상기 천정면의 하부에 구비되고 상기 천정면을 가열하는 가열수단; 및 상기 가열수단과 상기 천정면 사이에 구비되며, 상기 가열수단에 의해 열을 공급받아 상기 천정면 전체에 열과 습기를 공급하는 양생수단;을 포함하는 한중콘크리트 양생 시스템이 제공된다.

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Номер записи: 1
31-07-2017 дата публикации

싸이클로 헥센 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 대사성 질환의 예방 또는 치료용 약학적 조성물

Номер: KR0101763533B1
Автор: 양진, 김진웅, 이한규, 김재현, 손창모, 이규환, 황정운, 최형호, 김대훈, 이재걸
Принадлежит: 현대약품 주식회사

... 본 발명은 싸이클로 헥센 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 대사성 질환의 예방 또는 치료용 약학적 조성물에 관한 것으로, 본 발명에 따른 싸이클로 헥센 유도체는 GPR-119(G protein-coupled receptor 119)를 활성화시켜 cAMP(Cyclic adenosine monophosphate)의 세포 내 활성을 증가시키고, 신경 내분비 단백질인 GLP-1(Glucagon-like peptide-1) 방출을 유도하여 체중감소 및 혈당강하 효과가 동시에 나타나므로, 비만, I형 당뇨병, Ⅱ형 당뇨병, 부적합한 내당증, 인슐린 내성증, 고혈당증, 고지질혈증, 고중성지방혈증, 고콜레스테롤혈증, 이상지질혈증, X 증후군 등과 같은 대사성 질환의 예방 또는 치료용 약학적 조성물로 유용하게 사용할 수 있다.

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Номер записи: 2
27-10-2015 дата публикации

Lectern installed lift foothold

Номер: KR0101563622B1
Автор: 박재범, 양진
Принадлежит: 주식회사 건양기술공사 건축사사무소

... 강연대 또는 사회대의 하단에 수납이 가능한 유압식 리프트발판이 설치되어 강연자 또는 사회자의 키에 맞추어 상기 리프트발판의 높이를 조절할 수 있는 리프트발판이 설치된 강연대로써, 강연대 내부에 설치되는 유압식리프트; 상기 유압식리프트의 일측에 형성되는 발판; 그리고 상기 유압식리프트와 유선 또는 무선으로 연결되어 유압식리프트의 동작을 제어할 수 있는 리프트스위치로 구성된다.이로써 발표자의 키에 맞추어 강연대 하단의 발판을 조절하여 발표자의 키에 상관없이 강연대를 사용할 수 있게 되므로 발표자의 불편함을 해소시킬 수 있으며, 청중이 보기에도 미관을 해치지 않고 발표자를 용이하게 확인할 수 있게 된다.

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Номер записи: 3
18-08-2015 дата публикации

LIFT FOOTHOLD INSTALLED LECTURE TABLE

Номер: KR1020150093355A
Автор: PARK, JAE BUM, YAN, JIN
Принадлежит:

The present invention relates to a lift foothold installed lecture table. A hydraulic lift foothold capable of storing is installed in a lecture table or a lower end of a lectern to control a height of the lift foothold in correspondence to the height of a lecturer or a chairperson. The lift foothold comprises: a hydraulic lift installed inside the lecture table; a foothold formed on one side of the hydraulic lift; and a lift switch connected with the hydraulic lift either with or without a wire to the control actions of the hydraulic lift. Therefore, the foothold of the lower end of the lecture table is controlled to correspond to the height of a presenter in order to enable the presenter to use the lecture table regardless of the presenter′s height and remove the inconveniences to the presenter, and the present invention enables the audience to easily identify the presenter without bothering an aesthetical appearance. COPYRIGHT KIPO 2015 ...

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Номер записи: 4
24-12-2015 дата публикации

WATERPROOF SHEET FOR CONSTRUCTION

Номер: KR1020150144244A
Автор: YANG, JIN, KIM, DUK YONG
Принадлежит:

Disclosed is a waterproof sheet for construction. According to an aspect of the present disclosure, provided is a waterproof sheet for construction, wherein multiple rectangular unit waterproof sheets having first and second sides with a first length, parallel to each other and third and fourth sides with a second length shorter than the first length, perpendicular to the first and second sides, and parallel to each other and installed on a waterproofing target surface where waterproofing is necessary. Provided is the waterproof sheet for construction, including: insertion slits lengthily formed on the first side in the longitudinal direction of the first side and formed to have a preset depth in the longitudinal direction of the third and fourth sides; a joint unit lengthily formed on the second side in the longitudinal direction of the second side; two adhesive layers formed on the inner surface of the insertion slit and facing each other; and a detachable sheet attached to each of the ...

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Номер записи: 5
05-11-2015 дата публикации

CYCLOHEXENE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING METABOLIC DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT

Номер: WO2015167309A1
Автор: YANG, Jin, KIM, Jinwoong, LEE, Han Kyu, KIM, Jae Hyun, SON, Chang Mo, LEE, Kyu hwan, HWANG, Jeongun, CHOI, Hyung-Ho, KIM, deahoon, RHEE, Jaekeol
Принадлежит:

The present invention relates to: a cyclohexene derivative; a preparation method therefor; and a pharmaceutical composition for preventing or treating metabolic diseases, containing the same as an active ingredient. The cyclohexene derivative according to the present invention increases the intracellular activity of cyclic adenosine monophosphate (cAMP) by activating G protein-coupled receptor 119 (GPR-119) and simultaneously exhibits weight loss and hypoglycemic effects by inducing the release of glucagon-like peptide-1 (GLP-1), which is a neuroendocrine protein, and thus can be useful as a pharmaceutical composition for preventing or treating metabolic diseases such as obesity, type 1 diabetes, type 2 diabetes, inadequate glucose tolerance, insulin resistance, hyperglycemia, hyperlipidemia, hypertriglyceridemia, hypercholesterolemia, dyslipidemia and syndrome X.

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Номер записи: 6
24-12-2015 дата публикации

COLD WEATHER CONCRETE CURING SYSTEM

Номер: KR1020150144246A
Автор: YANG, JIN, KIM, DUK YONG
Принадлежит:

The present invention relates to a cold weather concrete curing system. According to one aspect of the present disclosure, provided is a cold weather concrete curing system comprising: a ceiling surface formed by pouring cold weather concrete; a heating means formed in the lower side of the ceiling surface and heating the ceiling surface; and a curing means arranged between the heating means and the ceiling surface and supplying heat and moisture to the entire ceiling surface by receiving heat from the heating means. COPYRIGHT KIPO 2016 ...

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Номер записи: 7
23-10-2014 дата публикации

NOVEL 3-(4-(BENZYLOXY)PHENYL)HEX-4-INOIC ACID DERIVATIVE, METHOD OF PREPARING SAME AND PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING METABOLIC DISEASE INCLUDING SAME AS EFFECTIVE INGREDIENT

Номер: WO2014171762A1
Автор: YANG, Jin, KIM, Jin Woong, LEE, Han Kyu, KIM, Jae Hyun, SON, Chang Mo, LEE, kyu hwan, CHOI, Hyung-Ho, KIM, daehoon, HA, Tae-Young, RHEE, Jaekeol
Принадлежит:

The present invention relates to a novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative, a method of preparing same and a pharmaceutical composition for preventing and treating metabolic disease including same as an effective ingredient. The novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative, an optical isomer thereof, or a pharmaceutically acceptable salt thereof, according to the present invention, has an excellent effect on activation of GPR40 protein and thus has excellent promoting effect of insulin secretion; is nontoxic when co-administrated with other drugs and is possibly co-administrated with other drugs; and has excellent effective effect of activating GPR40 protein in vivo. Therefore, a composition including the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative, the optical isomer thereof, or the pharmaceutically acceptable salt thereof may be availably used in a pharmaceutical composition for preventing and treating metabolic disease such as obesity, type I ...

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Номер записи: 8
28-04-2016 дата публикации

COMPLEX FORMULATION FOR USE IN PREVENTING OR TREATING METABOLIC DISEASES CONTAINING NOVEL 3-(4-(BENZYLOXY)PHENYL)HEX-4-INOIC ACID DERIVATIVE AND ANOTHER ACTIVE INGREDIENT

Номер: KR1020160046306A
Автор: YANG, JIN, KIM, JIN WONNG, LEE, HAN KYU, KIM, JAE HYUN, SON, CHANG MO, LEE, KYU HWAN, CHOI, HYUNG HO, KIM, DAE HOON, HA, TAE YOUNG, RHEE, JEA KEOL
Принадлежит:

The present invention relates to a pharmaceutical composition for preventing or treating metabolic diseases that may be administered in the form of a complex formulation of a combination of a novel 3-(4-benzyloxy)phenyl-hex-4-ionic acid derivative with at least one active ingredient selected from the group consisting of dipeptidyl peptidase-IV(DPPIV) inhibitors, sulfonylurea compounds, thiazolidinediones (TZD), biguanides and sodium/glucose cotransporter 2 (SGLT2) drugs. When using the composition, it is possible to obtain a significantly high anti-diabetic effect in an animal diabetes mellitus model. Thus, the composition can be used as a pharmaceutical composition for preventing or treating metabolic diseases, such as obesity, Type I diabetes, Type II diabetes, impaired glucose tolerance, insulin tolerance, hyperglycemia, hyperlipidemia, hypertriglyceridemia, hypercholesterolemia, dyslipidemia, X syndrome, or the like. COPYRIGHT KIPO 2016 (AA) Activity percentage (BB) LOG [concentration ...

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Номер записи: 9
17-06-2015 дата публикации

An apparatus for workers protect from falling objects

Номер: KR0101529466B1
Автор: 박재범, 양진
Принадлежит: (주)코리콘건설

... 항타시 사용되는 파일의 일정 높이 위에 우산과 같이 펼쳐지도록 된 차단막을 형성하여 이 차단막에 의해 항타시에 발생되는 토석이나 오일 등이 파일의 하부쪽에 있는 작업자에게 떨어지지 않게 할 수 있는 항타시 토석 및 오일 낙하 방지장치가 개시된다. 본 발명에 따른 토석 및 오일 낙하 방지장치는 파일 항타시 파일의 항타량을 체크하는 작업자에게 토석이나 오일이 떨어지는 것을 방지하기 위한 항타시 토석 및 오일 낙하 방지장치에 있어서, 파일을 헐렁하게 감싸는 밴드와, 밴드의 외주면상에 방사상으로 펼쳐지게 형성된 차단막과, 밴드가 일정 높이위에 위치하도록 지면으로 연장되는 스탠드를 포함하여 구성된다.

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Номер записи: 10
15-05-2017 дата публикации

CYCLOHEXENE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING METABOLIC DISEASES

Номер: KR1020170053118A
Автор: YANG, JIN, KIM, JIN WOONG, LEE, HAN KYU, KIM, JAE HYUN, SON, CHANG MO, LEE, KYU HWAN, HWANG, JEONG UN, CHOI, HYUNG HO, KIM, DAE HOON, RHEE, JAE KEOL
Принадлежит:

The present invention relates to a cyclohexene derivative, a preparation method of the same, and a pharmaceutical composition comprising the same as an active ingredient for preventing or treating metabolic diseases. The cyclohexene derivative according to the present invention increases the activity of cAMP (cyclic adenosine monophosphate) in the cell by activating GPR-119 (G protein-coupled receptor 119), and has simultaneous effects of weight loss and blood sugar reduction by inducing the release of a neuroendocrine protein, GLP-1 (glucagon-like peptide-1) and thus may be beneficially used as a pharmaceutical composition for preventing or treating metabolic diseases including obesity, type I diabetes, type II diabetes, inappropriate insulin resistance, insulin resistance syndrome, hyperglycemia, hyperlipidemia, hypertriglyceridemia, hypercholesterolemia, dyslipidemia, X syndrome, and the like. COPYRIGHT KIPO 2017 (AA) Weight change (g) (BB) Administration period (9 days) (CC) Untreated ...

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Номер записи: 11
22-05-2014 дата публикации

NOVEL PIPERAZINE DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALT OR OPTICAL ISOMER THEREOF, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING METABOLIC DISORDERS

Номер: WO2014077532A1
Автор: YANG, Jin, KIM, Jin Woong, LEE, Han Kyu, KIM, Jae Hyun, SON, Chang Mo, LEE, Kyu Hwan, CHOI, Hyung-Ho, KIM, Daehoon, CHOI, Hyo-sun, RHEE, Jaekeol
Принадлежит:

The present invention relates to a novel piperazine derivative, to a pharmaceutically acceptable salt or an optical isomer thereof, to a method for preparing same, and to a pharmaceutical composition containing same as an active ingredient for preventing or treating metabolic disorders. The novel piperazine derivative and the pharmaceutically acceptable salt or the isomer thereof, according to the present invention, have excellent in vivo absorptivity and outstanding safety in the human body, since the present invention has a higher water solubility than those of compounds conventionally known as GPR119 activators and has low cytotoxicity. Moreover, since the present invention has the excellent effect of promoting cAMP by activating GPR119, thereby having the significantly outstanding effect of reducing blood glucose in a single dose, the present invention can be effectively used as a pharmaceutical composition for preventing or treating obesity, type I diabetes, type II diabetes, inadequate ...

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Номер записи: 12
29-08-2016 дата публикации

싸이클로 헥센 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 대사성 질환의 예방 또는 치료용 약학적 조성물

Номер: KR0101651505B1
Автор: 양진, 김진웅, 이한규, 김재현, 손창모, 이규환, 황정운, 최형호, 김대훈, 이재걸
Принадлежит: 현대약품 주식회사

... 본 발명은 싸이클로 헥센 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 대사성 질환의 예방 또는 치료용 약학적 조성물에 관한 것으로, 본 발명에 따른 싸이클로 헥센 유도체는 GPR-119(G protein-coupled receptor 119)를 활성화시켜 cAMP(Cyclic adenosine monophosphate)의 세포 내 활성을 증가시키고, 신경 내분비 단백질인 GLP-1(Glucagon-like peptide-1) 방출을 유도하여 체중감소 및 혈당강하 효과가 동시에 나타나므로, 비만, I형 당뇨병, Ⅱ형 당뇨병, 부적합한 내당증, 인슐린 내성증, 고혈당증, 고지질혈증, 고중성지방혈증, 고콜레스테롤혈증, 이상지질혈증, X 증후군 등과 같은 대사성 질환의 예방 또는 치료용 약학적 조성물로 유용하게 사용할 수 있다.

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Номер записи: 13
17-11-2015 дата публикации

Novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative, preparation method thereof, and pharmaceutical composition for use in preventing or treating metabolic diseases containing the same as an active ingredient

Номер: KR0101569522B1
Автор: 양진, 김진웅, 이한규, 김재현, 손창모, 이규환, 최형호, 김대훈, 하태영, 이재걸
Принадлежит: 현대약품 주식회사

... 본 발명은 신규한 3-(4-(벤질옥시)페닐)헥스-4-이노익 산 유도체, 이의 제조방법, 및 이를 유효성분으로 포함하는 대사성 질환의 예방 또는 치료용 약학적 조성물에 관한 것으로, 본 발명에 따른 신규한 3-(4-(벤질옥시)페닐)헥스-4-이노익 산 유도체, 이의 광학 이성질체, 또는 이의 약학적으로 허용가능한 염은 GPR40 단백질을 활성시키는 효과가 뛰어나 이로 인한 인슐린 분비 촉진 효과가 뛰어나고 타 약물과 병용투여로 인한 독성이 없어 타 약물과의 병용투여가 가능하며 생체 내에서의 GPR40 단백질을 활성시키는 유효 효과가 상당히 뛰어나므로 이를 유효성분으로 함유하는 조성물은 비만, Ⅰ형 당뇨병, Ⅱ형 당뇨병, 부적합한 내당력, 인슐린 내성, 고혈당증, 고지질혈증, 고중성지방혈증, 고콜레스테롤혈증, 이상지질혈증, X 증후군 등의 대사성 질환 예방 또는 치료용 약학적 조성물로 유용하게 사용할 수 있다.

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Номер записи: 14
24-04-2017 дата публикации

신규한 3-(4-(벤질옥시)페닐)헥스-4-이노익 산 유도체 및 다른 유효성분을 포함하는 대사성 질환의 예방 또는 치료용 복합제제

Номер: KR0101728900B1
Автор: 양진, 김진웅, 이한규, 김재현, 손창모, 이규환, 최형호, 김대훈, 하태영, 이재걸
Принадлежит: 현대약품 주식회사

... 본 발명은 신규한 3-(4-(벤질옥시)페닐)헥스-4-이노익 산 유도체와 디펩티딜펩티데이즈 IV(Dipeptidyl peptidase-4, DPPIV) 억제제 계열, 설포닐우레아(Sulfonylurea) 계열, 치아졸리딘디온(Thiazolidinediones, TZD) 계열, 바이구아니드(Biguanide) 계열 및 SGLT2(sodium/glucose cotransporter 2) 억제제 계열 약물로 이루어지는 군으로부터 적어도 하나 이상의 다른 유효성분을 선택하여 병용 또는 복합제 형태로 투여할 수 있는 대사성 질환에 대한 예방 또는 치료용 약학적 조성물에 관한 것이다. 본 발명의 조성물을 이용함으로써, 다양한 동물 당뇨 질환 모델에서 현저히 우수한 혈당강하효과를 얻을 수 있고, 비만, Ⅰ형 당뇨병, Ⅱ형 당뇨병, 내당증, 인슐린 내성증, 고혈당증, 고지질혈증, 고중성지방혈증, 고콜레스테롤혈증, 이상지질혈증, X 증후군 등의 대사성 질환에 대한 예방 또는 치료용 약학적 조성물로 유용하게 사용할 수 있다.

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Номер записи: 15
21-04-2016 дата публикации

COMPOSITE PREPARATION, CONTAINING NOVEL 3-(4-(BENZYLOXY)PHENYL)HEX-4-INOIC ACID DERIVATIVE AND ANOTHER ACTIVE INGREDIENT, FOR PREVENTING OR TREATING METABOLIC DISEASES

Номер: WO2016060517A2
Автор: YANG, Jin, KIM, Jin Woong, LEE, Han Kyu, KIM, Jae Hyun, SON, Chang Mo, LEE, Kyu Hwan, CHOI, Hyung-Ho, KIM, Daehoon, HA, Tae-Young, RHEE, Jeakeol
Принадлежит:

The present invention relates to a pharmaceutical composition for preventing or treating metabolic diseases, in which a novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative and at least another active ingredient, which is selected from the group consisting of dipeptidyl peptidase-4 (DPPIV) inhibitor-based, sulfonylurea-based, thiazolidinedione (TZD)-based, biguanide-based, and sodium/glucose cotransporter 2 (SGLT2) inhibitor-based drugs, may be administered in combination or in the form of a composite preparation. The use of the composition of the present invention can provide a remarkably excellent blood sugar reducing effect in various animal diabetic disease models, and the composition of the present invention can be favorably used as a pharmaceutical composition for preventing or treating metabolic diseases, such as obesity, diabetes type I, diabetes type II, glucose intolerance symptoms, insulin resistance symptoms, hyperglycemia, hyperlipidemia, hypertriglyceridemia, hypercholesterolemia ...

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Номер записи: 16
12-11-2015 дата публикации

CYCLOHEXENE DERIVATIVES, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING METABOLIC DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT

Номер: KR1020150126564A
Автор: YANG, JIN, KIM, JIN WOONG, LEE, HAN KYU, KIM, JAE HYUN, SON, CHANG MO, LEE, KYU HWAN, HWANG, JEONG UN, CHOI, HYUNG HO, KIM, DEA HOON, RHEE, JAE KEOL
Принадлежит:

The present invention relates to cyclohexene derivatives, a method for producing the same, and a pharmaceutical composition for preventing or treating metabolic diseases, containing the same as an active ingredient. The cyclohexene derivatives in accordance with the present invention activate G protein-coupled receptor 119 (GPR-119) to increase intracellular activity of cyclic adenosine monophosphate (cAMP), and induce the release of neurosecretion protein glucagon-like peptide-1 (GLP-1) to simultaneously cause weight loss and a drop in blood sugar level. Therefore, the cyclohexene derivatives can be effectively used as a pharmaceutical composition for preventing or treating metabolic diseases such as obesity, type I diabetes, type II diabetes, impaired glucose tolerance, insulin resistance, hyperglycemia, hyperlipidemia, hypertriglyceridemia, hypercholesteremia, dyslipidemia, X syndrome, and the like. COPYRIGHT KIPO 2016 (AA) Weight change (g) (BB) Duration of administration (day) (CC) ...

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Номер записи: 17
21-04-2016 дата публикации

COMPOSITE PREPARATION, CONTAINING NOVEL 3-(4-(BENZYLOXY)PHENYL)HEX-4-INOIC ACID DERIVATIVE AND ANOTHER ACTIVE INGREDIENT, FOR PREVENTING OR TREATING METABOLIC DISEASES

Номер: WO2016060517A3
Автор: YANG, Jin, KIM, Jin Woong, LEE, Han Kyu, KIM, Jae Hyun, SON, Chang Mo, LEE, Kyu Hwan, CHOI, Hyung-Ho, KIM, Daehoon, HA, Tae-Young, RHEE, Jeakeol
Принадлежит:

The present invention relates to a pharmaceutical composition for preventing or treating metabolic diseases, in which a novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative and at least another active ingredient, which is selected from the group consisting of dipeptidyl peptidase-4 (DPPIV) inhibitor-based, sulfonylurea-based, thiazolidinedione (TZD)-based, biguanide-based, and sodium/glucose cotransporter 2 (SGLT2) inhibitor-based drugs, may be administered in combination or in the form of a composite preparation. The use of the composition of the present invention can provide a remarkably excellent blood sugar reducing effect in various animal diabetic disease models, and the composition of the present invention can be favorably used as a pharmaceutical composition for preventing or treating metabolic diseases, such as obesity, diabetes type I, diabetes type II, glucose intolerance symptoms, insulin resistance symptoms, hyperglycemia, hyperlipidemia, hypertriglyceridemia, hypercholesterolemia ...

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Номер записи: 18