02-01-2020 дата публикации
Номер: WO2020004745A1
Автор:
SONG, Byung Ho,
JEONG, Kwang Taek,
JI, Min Jae,
NAM, Da Yeong,
EOM, Hye Seon,
KIM, Ji Young
Принадлежит:
The present invention relates to a microneedle coated with a drug and a manufacturing method for same and, more specifically, to a microneedle coated with a drug and a manufacturing method for same, the microneedle delivering a drug by physically puncturing the stratum corneum of skin. The microneedle coated with a drug is represented by chemical formula 1 and is characterized in that the drug is discharged by means of an oxidation-reduction reaction after the skin is penetrated. [Chemical formula 1] MN-S-S-D In chemical formula 1, MN is the microneedle containing silica (SiO2), S-S is a disulfide bond, and D is the drug. The microneedle coated with a drug according to the present invention is useful as a functional cosmetic material having whitening, wrinkle softening, anti-inflammatory functions, and the like, by effectively delivering the drug which has excellent functions but low skin permeation.
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