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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 15. Отображено 15.
07-07-2016 дата публикации

GLYCYRRHIZIC ACID AND USE THEREOF

Номер: KR1020160080108A
Автор: KIM, SUNG MIN, PARK, KI DUK, KIM, SEUNG WOO, KIM, DONG JIN, PAE, AE NIM, KANG, YONG KOO, KIM, YUN KYUNG, CHOI, JI WON, YEON, SEUL KI, SONG, HYO JUNG, JU, EUN JI, JANG, BO KO
Принадлежит:

The present invention relates to a pharmaceutical composition for preventing or treating neuromyelitis optica (NMO), to a food composition for preventing or alleviating NMO, which comprises glycyrrhizic acid or pharmaceutically acceptable salts thereof as an active ingredient, and to a treatment method of NMO comprising a step of administering an individual with the pharmaceutical composition. COPYRIGHT KIPO 2016 ...

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Номер записи: 1
28-05-2015 дата публикации

COMPOSITION INCLUDING GLYCYRRHIZIC ACID OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF FOR PREVENTING OR TREATING NEUROMYELITIS OPTICA

Номер: KR1020150057503A
Автор: KIM, SUNG MIN, PARK, KI DUK, KIM, SEUNG WOO, KIM, DONG JIN, PAE, AE NIM, KANG, YONG KOO, KIM, YUN KYUNG, CHOI, JI WON, YEON, SEUL KI, SONG, HYO JUNG, JU, EUN JI, JANG, BO KO
Принадлежит:

The present invention relates to: a pharmaceutical composition including glycyrrhizic acid or pharmaceutically acceptable salts thereof for preventing or treating neuromyelitis optica (NMO); a food composition for preventing or treating NMO; and a method for treating NMO including a step of injecting the pharmaceutical composition into an object. COPYRIGHT KIPO 2015 ...

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Номер записи: 2
03-05-2018 дата публикации

FUNCTIONAL DERIVATIVE COMPOUNDS OF ALANINE AND PROLINE AMINO ACIDS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

Номер: WO2018080269A1
Автор: PARK, Ki Duk, BAHN, Yong-Sun, LEE, Jong-Seung, LEE, Kyung-Tae, PAE, Ae Nim, YEON, Seul Ki, KANG, Yong Koo, PARK, Jong Hyun, KIM, Siwon, JANG, Bo Ko, CHOI, Ji Won
Принадлежит:

The present invention relates to novel functional derivatives of alanine and proline amino acids. The compounds of the present invention were confirmed to have a very superior antifungal or fungicidal effect. In addition, the compounds of the present invention were confirmed to exhibit a synergistic effect when co-administered with an existing antifungal preparation. Moreover, the compounds of the present invention showed activity on a wide range of fungi. Therefore, the compounds of the present invention can be widely used in a field which requires the treatment with an antifungal or fungicidal preparation against human infectious fungi, animal infectious fungi, and phytopathogenic fungi.

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Номер записи: 3
10-04-2017 дата публикации

비닐 설폰 유도체, 이의 약학적으로 허용가능한 염 및 이를 유효성분으로 포함하는 시신경 척추염 예방 또는 치료용 약학조성물

Номер: KR0101720060B1
Автор: 박기덕, 배애님, 김동진, 강용구, 김윤경, 박종현, 연슬기, 주은지, 최지원, 장보고, 송효정, 김성민, 김승우, 천소영
Принадлежит: 한국과학기술연구원, 서울대학교병원

... 본 발명은 NMO-IgG와 아쿠아포린 4 단백질의 결합을 방지하는데 작용하는 비닐 설폰 유도체 화합물, 이의 약학적으로 허용가능한 염 및 이를 유효성분으로 포함하는 시신경척추염 예방 또는 치료용 약학조성물에 관한 것이다.

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Номер записи: 4
09-05-2018 дата публикации

FUNCTIONAL DERIVATIVE COMPOUND OF ALANINE AND PROLINE AMINO ACIDS AND PHARMACEUTICAL COMPOSITION INCLUDING SAME

Номер: KR1020180046730A
Автор: PARK, KI DUK, PAE, AE NIM, YEON, SEUL KI, KANG, YONG KOO, PARK, JONG HYUN, KIM, SI WON, JANG, BO KO, CHOI, JI WON, BAHN, YONG SUN, LEE, KYUNG TAE
Принадлежит:

The present invention relates to a benzyloxy-benzylaminyl amino acid derivative having an amino acid as a functional group and a pharmaceutical composition for an antifungal agent including the same as an active ingredient. The present invention comprises the benzyloxy-benzylaminyl amino acid derivative displayed by chemical formula 1 or pharmaceutically acceptable salts thereof. COPYRIGHT KIPO 2018 ...

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Номер записи: 5
12-04-2016 дата публикации

ALPHA-AMINOAMIDE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

Номер: KR1020160039817A
Автор: PARK, KI DUK, LEE, CHANG JOON, KIM, DONG JIN, PAE, AE NIM, CHOO, HYUN AH, MIN, SUN JOON, KANG, YOUG KOO, KIM, YUN KYUNG, SONG, HYO JUNG, CHOI, JI WON, NAM, MIN HO, HEO, JUN YOUNG, YEON, SEUL KI, JANG, BO KO, JU, EUN JI, JO, SEON MI
Принадлежит:

The present invention relates to an alpha-aminoamide derivative compound and a pharmaceutical composition comprising the same. According to various embodiments of the present invention, the pharmaceutical composition can overcome shortcomings of a conventional drug used as a MAO-B inhibitor. More particularly, the pharmaceutical composition reversibly suppresses MAO-B through a non-covalent bond, and thus can alleviate or remove side effects of a conventional drug which exhibits treatment efficacy by irreversibly acting with MAO-B through a covalent bond. Particularly, the novel compound of the present invention has remarkable stability and efficacy in comparison to a conventional reversible MAO-B inhibitor. The alpha-aminoamide derivative compound is represented by chemical formula 1. COPYRIGHT KIPO 2016 ...

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Номер записи: 6
28-05-2015 дата публикации

PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OPTIC NEUROMYELITIS COMPRISING GLYCYRRHIZIC ACID OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AS AN ACTIVE INGREDIENT

Номер: WO2015076553A1
Автор: KIM, Sung Min, PARK, Ki Duk, KIM, Seung Woo, KIM, Dong Jin, PAE, Ae Nim, KANG, Yong Koo, KIM, Yun Kyung, CHOI, Ji Won, YEON, Seul Ki, SONG, Hyo Jung, JU, Eun Ji, JANG, Bo Ko
Принадлежит:

The present invention relates to a pharmaceutical composition for preventing or treating optic neuromyelitis (neuromyelitis optica, NMO) and a food composition for preventing or alleviating optic neuromyelitis, which composition comprises glycyrrhizic acid or pharmaceutically acceptable salt thereof as an active ingredient, and relates to an optic neuromyelitis treatment method comprising a step of administering an individual with the pharmaceutical composition.

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Номер записи: 7
23-12-2016 дата публикации

VINYLSULFONE DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NEUROMYELITIS OPTICA, COMPRISING SAME AS ACTIVE INGREDIENT

Номер: KR1020160147420A
Автор: PARK, KI DUK, PAE, AE NIM, KIM, DONG JIN, KANG, YONG KOO, KIM, YUN KYUNG, PARK, JONG HYUN, YEON, SEUL KI, JU, EUN JI, CHOI, JI WON, JANG, BO KO, SONG, HYO JUNG, KIM, SUNG MIN, KIM, SEUNG WOO, CHEON, SO YOUNG
Принадлежит:

The present invention relates to a vinylsulfone derivative compound which acts to prevent binding of NMO-IgG and aquaporin 4, pharmaceutically acceptable salt thereof, and a pharmaceutical composition for preventing or treating neuromyelitis optica comprising the same, as an active ingredient. COPYRIGHT KIPO 2017 ...

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Номер записи: 8
20-02-2020 дата публикации

NOVEL HALO-(3-(PHENYLSULFONYL)PROP-1-ENYL)PYRIDINE DERIVATIVE AND USE THEREOF

Номер: WO2020036474A1
Автор: PARK, Ki Duk, PAE, Ae Nim, LIM, Sang Min, PARK, Jong Hyun, CHOI, Ji Won, KIM, Siwon, KIM, Hyeon Jeong, YEON, Seul Ki
Принадлежит:

The present invention relates to a novel halo-(3-(phenylsulfonyl)prop-1-enyl)pyridine derivative or a pharmaceutically acceptable salt thereof, a method for producing same, and an NRF2 activator and a pharmaceutical composition which comprise same as an active ingredient, the pharmaceutical composition being for preventing or treating diseases induced by a reduction in NRF2 activity.

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Номер записи: 9
14-01-2019 дата публикации

글리시리직애씨드 및 이의 용도

Номер: KR0101937435B1
Автор: 김성민, 박기덕, 김승우, 김동진, 배애님, 강용구, 김윤경, 최지원, 연슬기, 송효정, 주은지, 장보고
Принадлежит: 서울대학교병원, 한국과학기술연구원

... 본 발명은 글리시리직애씨드(glycyrrhizic acid) 또는 이의 약학적으로 허용가능한 염을 유효성분으로 포함하는, 시신경 척수염(neuromyelitis optica, NMO)의 예방 또는 치료용 약학적 조성물, 시신경 척수염의 예방 또는 개선용 식품 조성물 및 상기 약학적 조성물을 개체에 투여하는 단계를 포함하는 시신경 척수염의 치료 방법에 관한 것이다.

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Номер записи: 10
07-04-2016 дата публикации

ALPHA-AMINOAMIDE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

Номер: WO2016052928A1
Автор: PARK, Ki Duk, LEE, Chang Joon, KIM, Dong Jin, PAE, Ae Nim, CHOO, Hyun Ah, MIN, Sun Joon, KANG, Yong Koo, KIM, Yun Kyung, SONG, Hyo Jung, CHOI, Ji Won, NAM, Min Ho, HEO, Jun Young, YEON, Seul Ki, JANG, Bo Ko, JU, Eun Ji, JO, Seon Mi
Принадлежит:

The present invention relates to an alpha-aminoamide derivative compound and a pharmaceutical composition comprising the same. According to various embodiments of the present invention, provided is a therapeutic agent which can overcome the disadvantages of conventional drugs used as a MAO-B inhibitor and, more specifically, reversibly inhibits MAO-B through a non-covalent bond so as to alleviate or eliminate the side effects of conventional drugs by irreversibly acting via a covalent bond with MAO-B to exhibit a therapeutic effect. Particularly, a new compound may be provided having superior stability and efficacy compared to a conventional reversible MAO-B inhibitor.

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Номер записи: 11
15-03-2017 дата публикации

PYRIMIDINE-CARBOXYLATE DERIVATIVE FOR PREVENTING OR TREATING NEUROMYELITIS OPTICA

Номер: KR101715127B1
Автор: PARK, KI DUK, PAE, AE NIM, KIM, DONG JIN, CHO, NAM CHUL, PARK, JONG HYUN, CHOI, JI WON, YEON, SEUL KI, HA, TAE HWAN, JANG, BO KO, JU, EUN JI, KIM, SUNG MIN, CHEON, SO YOUNG, KIM, HEE JAUNG, JANG, JAE WAN
Принадлежит: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY, SEOUL NATIONAL UNIVERSITY HOSPITAL

The present invention relates to a pharmaceutical composition capable of preventing or treating diseases caused by the combination of NMO-IgG and aquaporin 4 protein, and preferably neuromyelitis optica or degenerative nervous system diseases. The composition comprises a pyrimidine-carboxylate derivative or pharmaceutically acceptable salt thereof, or a solvate thereof, as an active ingredient, thereby inhibiting the combination of the NMO-IgG and the aquaporin 4 protein. COPYRIGHT KIPO 2017 ...

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Номер записи: 12
28-03-2017 дата публикации

ACRYLONITRILE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME

Номер: KR1020170034093A
Автор: PARK, KI DUK, KIM, YUN KYUNG, KIM, DONG JIN, PAE, AE NIM, MIN, SUN JOON, KANG, YONG KOO, LIM, SUNG SU, CHOI, JI WON, YEON, SEUL KI, PARK, JONG HYUN, HA, TAE HWAN, JU, EUN JI, JANG, BO KO
Принадлежит:

The present invention relates to acrylonitrile compounds and pharmaceutical compositions containing the same, and more particularly, to acrylonitrile compounds and pharmaceutical compositions containing the same, which suppress deformation such as oligomer formation of tau protein in a cell to prevent tauopathy so that the present invention can be used for preventing and treating a neurodegenerative disease. COPYRIGHT KIPO 2017 (AA) Compound 6a ...

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Номер записи: 13
02-11-2017 дата публикации

아크릴로니트릴 화합물 및 이를 포함하는 약학 조성물

Номер: KR0101793254B1
Автор: 박기덕, 김윤경, 김동진, 배애님, 민선준, 강용구, 임성수, 최지원, 연슬기, 박종현, 하태환, 주은지, 장보고
Принадлежит: 한국과학기술연구원

... 본 발명은 아크릴로니트릴 화합물 및 이를 포함하는 약학적 조성물에 관한 것으로, 보다 상세하게는, 세포 내 타우 단백질의 올리고머 형성과 같은 변형을 억제하여 타우병증을 방지함으로써 신경 뇌질환 질환의 예방 및 치료를 위해 사용될 수 있는 아크릴로니트릴 화합물 및 이를 포함하는 약학적 조성물에 관한 것이다.

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Номер записи: 14
28-11-2016 дата публикации

알파-아미노아미드 유도체 화합물 및 이를 포함하는 약학적 조성물

Номер: KR0101679568B1
Автор: 박기덕, 이창준, 김동진, 배애님, 추현아, 민선준, 강용구, 김윤경, 송효정, 최지원, 남민호, 허준영, 연슬기, 장보고, 주은지, 조선미
Принадлежит: 한국과학기술연구원

... 발명은 알파-아미노아미드 유도체 화합물 및 이를 포함하는 약학적 조성물에 관한 것이다. 본 발명의 여러 구현예에 따르면, MAO-B 저해제로 사용되는 기존 약물의 단점을 극복할 수 있으며, 구체적으로는 MAO-B와 공유결합을 통해 비가역적으로 작용하여 치료 효과를 나타내는 기존 약물의 부작용을 완화 혹은 없앨 수 있도록 비공유 결합을 통해 가역적으로 MAO-B를 억제하는 치료제를 제공할 수 있다. 특히 기존의 가역적 MAO-B 저해제 보다 뛰어난 안정성 및 효능을 갖는 새로운 화합물을 제공할 수 있다.

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Номер записи: 15