03-05-2018 дата публикации
Номер: KR1020180044617A
Принадлежит:
The present invention relates to a cell aging diagnosing biomarker composition comprising UHRF1 and DNMT1. Specifically, the present invention relates to a biomarker composition for diagnosing cell aging, a kit for diagnosing cell aging using the same, and a method for diagnosing cell aging, wherein the biomarker composition comprises: a UHRF1 gene or a protein encoded with the UHRF1 gene; and a DNMT1 gene or a protein encoded with the DNMT1 gene. In addition, the present invention provides a pharmaceutical composition for preventing or treating cell aging, wherein the pharmaceutical composition comprises a UHRF1 protein and a DNMT1 protein, or an expression promoter or activator of the UHRF1 protein and DNMT1 protein as an active ingredient; and a method for screening a cell aging therapeutic agent using the UHRF1 protein and DNMT1 protein. Therefore, the UHRF1 or DNMT1 of the present invention can be useful in diagnosing and treating cell aging. COPYRIGHT KIPO 2018 ...
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