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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 35. Отображено 35.
02-08-2017 дата публикации

PRODUCTION METHOD OF CHIRAL BETA-AMINO ACID DERIVATIVE BY ASYMMETRIC HYDROGENATION REACTION USING CINCHONA-DERIVED ORGANIC CATALYST

Номер: KR101764185B1
Автор: LEE, PHIL HO, LEE, KOO YEON, UM, KYU SIK, KIM, CHEOL EUI
Принадлежит: KNU-INDUSTRY COOPERATION FOUNDATION

The present invention provides a production method of a chiral beta-amino acid derivative by an asymmetric hydrogenation reaction using a cinchona-derived organic catalyst. The production method of a chiral beta-amino acid derivative of the present invention can be used as a production method of a chiral compound, and a method synthesizing an optically high-purity compound in an ezetimibe synthesis field. COPYRIGHT KIPO 2017 ...

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Номер записи: 1
06-07-2018 дата публикации

ANTIOXIDANT OR WHITENING COSMETIC COMPOSITION COMPRISING SOLVENT FRACTION OF MISTLETOE EXTRACT AND ACTIVE MATERIAL ISOLATED THEREFROM

Номер: KR1020180077117A
Автор: LEE KOO YEON, PARK CHUL SUN
Принадлежит:

The present invention provides an antioxidant or whitening cosmetic composition comprising an ethyl acetate fraction or a butanol fraction separated from a mistletoe extract and an active material isolated therefrom. The composition comprising the specific solvent fraction or the active material isolated therefrom of the present invention exhibits excellent antioxidant activity and whitening activity and can be usefully used as an antioxidant or whitening cosmetic composition. COPYRIGHT KIPO 2018 ...

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Номер записи: 2
23-08-2018 дата публикации

COSMETIC COMPOSITION FOR WHITENING INCLUDING AURONE COMPOUND

Номер: KR1020180094450A
Автор: LEE, KOO YEON, HWANG, WOON SANG
Принадлежит:

The present invention provides a cosmetic composition for whitening including an aurone compound of a specific structure and cosmetics including the same. The cosmetic composition including an aurone compound of a specific structure according to the present invention can be usefully used as the cosmetic composition for whitening in a cosmetics field. The aurone compound of a specific structure included in the cosmetic composition for whitening has tyrosinase inhibitory activity. Ascorbic acid is used as a positive control group. COPYRIGHT KIPO 2018 ...

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Номер записи: 3
27-12-2018 дата публикации

퓨로쿠마린 화합물을 포함하는 미백용 화장료 조성물

Номер: KR0101933164B1
Автор: 이구연, 김재현
Принадлежит: 강원대학교산학협력단

... 본 발명은 특정 구조의 퓨로쿠마린 화합물을 포함하는 미백용 화장료 조성물 및 이를 포함하는 화장품을 제공한다. 본 발명의 특정 구조의 퓨로쿠마린 화합물을 포함하는 화장료 조성물은 화장품 분야에서 미백용 화장료 조성물로서 유용하게 사용될 수 있다.

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Номер записи: 4
21-05-2018 дата публикации

꼬리겨우살이 추출물의 용매 분획물 및 이로부터 분리된 활성 물질을 포함하는 항산화 또는 미백용 화장료 조성물

Номер: KR0101859986B1
Автор: 이구연, 박철선
Принадлежит: 강원대학교산학협력단

... 본 발명은 꼬리겨우살이 추출물로부터 분획된 에틸아세테이트 분획물 또는 부탄올 분획물; 및 이로부터 분리된 활성 물질을 포함하는 항산화 또는 미백용 화장료 조성물을 제공한다. 본 발명의 특정 용매 분획물 또는 이로부터 분리된 활성 물질을 포함하는 조성물은 우수한 항산화 활성 및 미백 활성을 나타내어, 항산화 또는 미백용 화장료 조성물로서 유용하게 사용될 수 있다.

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Номер записи: 5
06-07-2018 дата публикации

겨우살이 추출물의 용매 분획물 및 이로부터 분리된 활성 물질을 포함하는 항산화 또는 미백용 화장료 조성물

Номер: KR0101875547B1
Автор: 이구연, 박철선
Принадлежит: 강원대학교산학협력단

... 본 발명은 겨우살이 추출물로부터 분획된 에틸아세테이트 분획물 또는 부탄올 분획물; 및 이로부터 분리된 활성 물질을 포함하는 항산화 또는 미백용 화장료 조성물을 제공한다. 본 발명의 특정 용매 분획물 또는 이로부터 분리된 활성 물질을 포함하는 조성물은 우수한 항산화 활성 및 미백 활성을 나타내어, 항산화 또는 미백용 화장료 조성물로서 유용하게 사용될 수 있다.

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Номер записи: 6
02-08-2018 дата публикации

겨우살이 추출물의 용매 분획물 및 이로부터 분리된 활성 물질을 포함하는 항산화 또는 미백용 화장료 조성물

Номер: KR0101884794B1
Автор: 이구연, 박철선
Принадлежит: 강원대학교산학협력단

... 본 발명은 겨우살이 추출물로부터 분획된 에틸아세테이트 분획물 또는 부탄올 분획물; 및 이로부터 분리된 활성 물질을 포함하는 항산화 또는 미백용 화장료 조성물을 제공한다. 본 발명의 특정 용매 분획물 또는 이로부터 분리된 활성 물질을 포함하는 조성물은 우수한 항산화 활성 및 미백 활성을 나타내어, 항산화 또는 미백용 화장료 조성물로서 유용하게 사용될 수 있다.

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Номер записи: 7
20-08-2015 дата публикации

ELECTROCARDIOGRAM SIGNAL ANALYSIS SEVER AND ELECTROCARDIOGRAM SIGNAL ANALYSIS SYSTEM INCLUDING SAME

Номер: KR1020150094920A
Автор: LEE, KU YEON, KANG, KYUNG TAE
Принадлежит:

Provided is an electrocardiogram signal analysis server. The electrocardiogram signal analysis server includes a receiving unit for receiving an electrocardiogram signal of a user and user information from a user terminal, an electrocardiogram signal analyzing unit for analyzing the received electrocardiogram signal, an electrocardiogram signal storing unit for storing a result of the electrocardiogram signal analysis corresponding to the user information, and a transmitting unit for transmitting the result of the electrocardiogram signal analysis to a health care facility server. COPYRIGHT KIPO 2015 (112) Reception unit (114) Transmission unit (120) Electrocardiogram signal analyzing unit (130) Electrocardiogram signal storing unit (140) Electrocardiogram signal analysis result processing unit (150) Electrocardiogram signal searching unit ...

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Номер записи: 8
18-06-2018 дата публикации

TANGRAM ALARM CLOCK

Номер: KR1020180065436A
Автор: LEE, KU YEON
Принадлежит:

The objective of the present invention is to prevent a user from falling asleep since failing in absolutely awaking from sleep even after hearing an alarm. More specifically, the present invention relates to an alarm clock using a tangram, allowing an alarm to be stopped only when a provided tangram puzzle after the alarm rings, thereby allowing a user to be absolutely awakened from sleep. Furthermore, the alarm clock can be used as a teaching tool or a playing tool. COPYRIGHT KIPO 2018 ...

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Номер записи: 9
19-09-2016 дата публикации

4,5-다이하이드로-1Ｈ-피라졸 유도체 또는 그의 염 및 이를 포함하는 약학 조성물

Номер: KR0101657594B1
Автор: 박찬선, 김영환, 이규진, 허윤, 정은혜, 탁희재, 신승엽, 이호진, 이춘호, 이구연
Принадлежит: 주식회사유한양행

... 본 발명은 4,5-다이하이드로-1Ｈ-피라졸 유도체 또는 그의 약학적으로 허용가능한 염, 이의 제조방법, 및 이를 포함하는 약학 조성물을 제공한다. 상기 4,5-다이하이드로-1Ｈ-피라졸 유도체 또는 그의 약학적으로 허용가능한 염은 LXR 전사활성을 효과적으로 증가시킴으로써, 콜레스테롤 담석, 고지혈증, 관상 및 죽상 동맥경화증 등을 포함한 콜레스테롤 대사이상의 예방 및 치료에 유용하게 적용될 수 있다.

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Номер записи: 10
04-01-2018 дата публикации

COSMETIC COMPOSITION FOR ANTI-OXIDATION OR WHITENING COMPRISING SOLVENT FRACTION OF VISCUM ALBUM EXTRACT AND ACTIVE MATERIALS ISOLATED THEREFROM

Номер: KR1020180001232A
Автор: LEE, KOO YEON, PARK, CHUL SUN
Принадлежит:

The present invention provides: an ethyl acetate fraction or a butanol fraction isolated from a Viscum album extract; and a cosmetic composition for anti-oxidation or whitening comprising active materials isolated therefrom. The composition comprising a specific solvent fraction or the active materials isolated therefrom of the present invention exhibits excellent antioxidant and whitening activity and can be usefully used as an antioxidant or whitening cosmetic composition. COPYRIGHT KIPO 2018 ...

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Номер записи: 11
05-09-2016 дата публикации

MANUFACTURING METHOD OF AURONE DERIVATIVE USING Ag CATALYST

Номер: KR101654109B1
Автор: LEE, KOO YEON, CHOI, HYUCK
Принадлежит: KNU-INDUSTRY COOPERATION FOUNDATION

Provided is a manufacturing method of aurone derivative. The manufacturing method of aurone derivative comprises a step of making o-hydroxylaryl phenylethynyl ketone react under the presence of an Ag catalyst and a dimethylformamide solvent. The manufacturing method of aurone derivative using Ag catalyst is quick and efficient, and is useful in fields requiring synthesis of aurone derivative having various structures. COPYRIGHT KIPO 2016 ...

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Номер записи: 12
10-12-2015 дата публикации

MANUFACTURING METHOD OF SYRUP WITH INCREASED CONTENTS OF RUTIN AND QUERCETIN FROM FAGOPYRUM ESCULENTUM

Номер: KR101576209B1
Автор: PARK, CHEOL HO, CHOE, MYEON, LEE, GU YEON, KIM, TAE WOO, IM, JAE CHEON
Принадлежит: KNU-INDUSTRY COOPERATION FOUNDATION, CHEORWON ECO-FRIENDLY AGRICULTURAL COOPERATIVE

The present invention relates to Fagopyrum esculentum syrup manufactured through enzyme treatment and a manufacturing method thereof. The Fagopyrum esculentum syrup with increased rutin and quercetin can be manufactured by treating alpha-amylase and glucoamylase in order. The purpose of the present invention is to develop and provide Fagopyrum esculentum syrup with the increased content of rutin and quercetin and a manufacturing method thereof. COPYRIGHT KIPO 2016 (AA) Content comparison of Rutin and Quercetin of Syrup with respect to enzyme treatment (BB) Contents(μg, mL) (CC) Immeately after enzyme treatment ...

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Номер записи: 13
06-07-2018 дата публикации

ANTIOXIDANT OR WHITENING COSMETIC COMPOSITION COMPRISING SOLVENT FRACTION OF MISTLETOE EXTRACT AND ACTIVE MATERIAL ISOLATED THEREFROM

Номер: KR1020180077118A
Автор: LEE KOO YEON, PARK CHUL SUN
Принадлежит:

The present invention provides an antioxidant or whitening cosmetic composition comprising an ethyl acetate fraction or a butanol fraction separated from a mistletoe extract and an active material isolated therefrom. The composition comprising the specific solvent fraction or the active material isolated therefrom of the present invention exhibits excellent antioxidant activity and whitening activity and can be usefully used as an antioxidant or whitening cosmetic composition. COPYRIGHT KIPO 2018 ...

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Номер записи: 14
16-07-2015 дата публикации

METHOD FOR PREPARING 2-TETRALONE DERIVATIVE USING BISMUTH/SILVER MIXED CATALYST

Номер: KR1020150083031A
Автор: LEE, KOO YEON, LEE, PHIL HO, KIM, JAE HYUN, PARK, JUNG MIN, YUN, JI HEE
Принадлежит:

The present invention relates to a method for preparing a 2-tetralone derivative using a bismuth/silver mixed catalyst in a simple and efficient manner. According to the method, a target material can be obtained within short time as the bismuth/silver mixed catalyst is used. The 2-tetralone derivative, prepared by the method, can be used to synthesize pharmaceutical products and intermediates of natural materials. The 2-tetralone derivative is represented by Chemical formula 1. COPYRIGHT KIPO 2015 ...

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Номер записи: 15
01-05-2014 дата публикации

4,5-DIHYDRO-1H-PYRAZOLE DERIVATIVE OR SALTS THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

Номер: WO2014065575A1
Автор: PARK, Chan-Sun, KIM, Young-Hwan, LEE, Gyu-Jin, HUR, Youn, JUNG, Eun-Hye, TAK, Hee-Jae, SHIN, Seung-Yub, LEE, Ho-Jin, LEE, Chun-Ho, LEE, Koo-Yeon
Принадлежит:

The present invention provides 4,5-dihydro-1H-pyrazole derivative or pharmaceutically acceptable salts thereof, a method for preparing same and a pharmaceutical composition comprising same. The 4,5-dihydro-1H-pyrazole derivative or pharmaceutically acceptable salts thereof may effectively increase LXR transcriptional activity, and therefore, can be usefully applied to the prevention and treatment of cholesterol metabolism disorders including cholesterol gallstones, hyperlipidemia, coronary sclerosis and atherosclerosis.

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Номер записи: 16
18-08-2015 дата публикации

COSMETIC COMPOSITION COMPRISING NITROTOLUENE DERIVATIVES FOR SKIN BRIGHTENING

Номер: KR101545462B1
Автор: KEE YUN, LEE, KOO YEON, HWANG BYUNG JOON, KWAK, JIN A, JUNG, YOO JUNG
Принадлежит: KNU-INDUSTRY COOPERATION FOUNDATION

The present invention relates to a cosmetic composition comprising nitrotoluene derivatives for skin brightening. According to an embodiment of the present invention, the composition comprising nitrotoluene derivatives has excellent skin brightening effect by inhibiting an activity of tyrosinase and production of melanin, and can be used for developing cosmetic products with enhanced brightening functionality. COPYRIGHT KIPO 2015 ...

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Номер записи: 17
02-08-2018 дата публикации

겨우살이 추출물의 용매 분획물 및 이로부터 분리된 활성 물질을 포함하는 항산화 또는 미백용 화장료 조성물

Номер: KR0101884795B1
Автор: 이구연, 박철선
Принадлежит: 강원대학교산학협력단

... 본 발명은 겨우살이 추출물로부터 분획된 에틸아세테이트 분획물 또는 부탄올 분획물; 및 이로부터 분리된 활성 물질을 포함하는 항산화 또는 미백용 화장료 조성물을 제공한다. 본 발명의 특정 용매 분획물 또는 이로부터 분리된 활성 물질을 포함하는 조성물은 우수한 항산화 활성 및 미백 활성을 나타내어, 항산화 또는 미백용 화장료 조성물로서 유용하게 사용될 수 있다.

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Номер записи: 18
07-02-2018 дата публикации

METHOD FOR PREPARING FUNCTIONAL BREWED COFFEE HAVING INCREASED POLYPHENOL CONTENT

Номер: KR1020180013042A
Автор: LEE, KOO YEON, HWANG, WOON SANG
Принадлежит:

Provided is aronia extract added brewed coffee comprising an aronia extract. The aronia extract added brewed coffee of the present invention has the increased total polyphenol content and total flavonoid content and has the reduced caffeine content, thereby satisfying preference of consumers who pursue various flavors and producing brewed coffee products with the increased bioactive materials which are good for health. Accordingly, the aronia extract added brewed coffee can be usefully used as functional brewed coffee with the increased polyphenol content in a coffee manufacturing field. COPYRIGHT KIPO 2018 (AA) Dutch coffee (1/64) (BB) Buckwheat syrup coffee (1/64) (CC) Aronia coffee (1/64) ...

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Номер записи: 19
27-12-2018 дата публикации

오론 화합물을 포함하는 미백용 화장료 조성물

Номер: KR0101933165B1
Автор: 이구연, 황운상
Принадлежит: 강원대학교산학협력단

... 본 발명은 특정 구조의 오론 화합물을 포함하는 미백용 화장료 조성물; 및 이를 포함하는 화장품을 제공한다. 본 발명의 특정 구조의 오론 화합물을 포함하는 화장료 조성물은 화장품 분야에서 미백용 화장료 조성물로서 유용하게 사용될 수 있다.

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Номер записи: 20
23-03-2023 дата публикации

신규한 카나비디올 유도체, 이의 제조방법 및 이를 포함하는 인지기능 개선용 조성물

Номер: KR20230040917A
Автор: 이구연
Принадлежит:

... 본 발명은 카나비디올 유도체, 이의 제조방법 및 이를 포함하는 인지기능 개선용 조성물을 제공한다. 본 발명의 신규한 카나바디올 유도체는 아세틸콜린에스테라제 저해 효능 및 부틸릴콜린에스테라제 저해 효능뿐만 아니라 모노아민 옥시다아제 B에 대한 저해 효능을 나타내는 것으로 확인되어, 치매 환자들에게서 나타나는 뇌조직 내의 아세틸콜린 수준 저하 및 혈중 부티릴콜린 수준 저하를 동시에 달성할 수 있고, 뇌세포 손상을 막음으로써 보다 효과적인 인지기능 개선 치료 효과를 기대할 수 있다. 따라서, 본 발명의 카나비디올 유도체, 이의 제조방법, 및 이를 유효성분으로 포함하는 인지기능 개선용 조성물은 아세틸콜린에스테라제, 부티릴콜린에스테라제 및 모노아민 옥시다아제 B를 동시에 저해하는 물질로 의약 및 건강기능식품 분야에서 인지기능 개선 물질로서 유용하게 사용될 수 있다.

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Номер записи: 21
23-08-2018 дата публикации

COSMETIC COMPOSITION FOR SKIN WHITENING COMPRISING FUROCOUMARIN COMPOUND

Номер: KR1020180094451A
Автор: LEE, KOO YEON, KIM, JAE HYUN
Принадлежит:

The present invention provides a cosmetic composition for skin whitening comprising a furocoumarin compound with a specific structure, and a cosmetic product containing the same. The cosmetic composition for skin whitening comprising a furocoumarin compound with a specific structure can be usefully used as a cosmetic composition for skin whitening in the field of cosmetics. The furocoumarin compound with a specific structure exhibits excellent tyrosinase inhibiting activity. COPYRIGHT KIPO 2018 ...

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Номер записи: 22
30-10-2017 дата публикации

PRODUCT HISTORY TRACKING DEVICE DETACHABLE IN MANUFACTURING MOLD AND METHOD FOR MANUFACTURING MOLD USING SAME

Номер: KR1020170119897A
Автор: KIM, HAK KWON, KIM, MIN KI, LEE, KU YEON
Принадлежит:

Disclosed are a product history tracking device detachable in manufacturing a mold and a method for manufacturing a mold using the same. The present invention provides a detachable product history tracking device which comprises an identification plate engraved with a QR code, a double-sided adhesive means located below the identification plate, and a magnetic plate attached to the lower part of the double-sided adhesive means and having an adhesive force between the identification plate and the raw material of the mold, and a method for manufacturing a mold which operates together with a product history tracking application in a smart phone by using the same. COPYRIGHT KIPO 2017 (AA) Start (BB) End (S100) Prepare a raw material (S102) Prepare an application program for tracking the history of a product running on a smartphone (S104) Install and run the application program for tracking the product history (S106) Set a reference surface of the raw material (S108) Attach a product history ...

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Номер записи: 23
09-06-2016 дата публикации

APPARATUS AND METHOD FOR SIMPLIFYING HL7 MESSAGE TO MONITOR BIOMETRIC DATA IN REAL TIME

Номер: KR101629144B1
Автор: KANG, KYUNG TAE, LEE, KU YEON
Принадлежит: INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS

The present invention relates to an apparatus for simplifying a health level 7 (HL7) message to monitor biometric data in real time. The apparatus includes a data acquisition unit, a normalization unit, a message creation unit, and an analysis unit. The data acquisition unit acquires biometric data of a target. The normalization unit normalizes the acquired biometric data. The message creation unit creates a first HL7 message based on the normalized biometric data. The analysis unit analyzes the first HL7 message. The message creation unit creates a second HL7 message by removing a repeated part of the first HL7 message based on an analysis result. According to the present invention, the message can be reduced by removing the repeated part from the first HL7 message and inserting a repetition separator into the removed part. COPYRIGHT KIPO 2016 (30) Simplifying an HL7 message (AA) Network ...

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Номер записи: 24
12-09-2016 дата публикации

MANUFACTURING METHOD OF COUMARIN DERIVATIVE USING PHENOL AND PROPIOLIC ACID

Номер: KR101656876B1
Автор: LEE, KOO YEON, CHOI, HYUCK
Принадлежит: KNU-INDUSTRY COOPERATION FOUNDATION

Provided is a manufacturing method of coumarin derivative. The manufacturing method of coumarin derivative comprises a step of making a phenol compound react with a propiolic acid compound. According to the present invention, the manufacturing method of coumarin derivative is quick and efficient, and is useful to fields requiring synthesis of coumarin derivatives of various structures. COPYRIGHT KIPO 2016 ...

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Номер записи: 25
30-06-2016 дата публикации

COSMETIC COMPOSITION FOR ANTI-INFLAMMATION AND ANTI-ALLERGY, CONTAINING FERMENTED EXTRACT OF MISTLETOE

Номер: KR101634670B1
Автор: LEE, KOO YEON, LEE, DEUG CHAN, PARK, CHUL SUN, AHN, SE JIN, YOO, GA EUN
Принадлежит: KNU-INDUSTRY COOPERATION FOUNDATION

Provided is a cosmetic composition for anti-inflammation and anti-allergy, containing a fermented extract of mistletoe. The composition containing the fermented extract of mistletoe does not cause cytotoxicity and inhibits the activity of microphage. In addition, the composition also has excellent effects of inhibiting degranulation, in accordance with the treated concentration of the extract. Thus, the composition of the present invention can be useful as a cosmetic composition for anti-inflammation and anti-allergy. COPYRIGHT KIPO 2016 (AA) Non-fermented extract (BB) Fermented extract ...

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Номер записи: 26
03-04-2018 дата публикации

COMPOSITION FOR INHIBITING ACTIVATION OF MAST CELLS CONTAINING CINNAMALDEHYDE DERIVATIVE

Номер: KR101844828B1
Автор: LEE, DEUG CHAN, LEE, KU YEON, PARK, JI EUN
Принадлежит: KNU-INDUSTRY COOPERATION FOUNDATION

The present invention relates to a composition for preventing and treating allergic diseases or excessive immune disease, containing at least one of 4-chloro-cinnamaldehyde and 4-trifluoromethyl-cinnamaldehyde as an active ingredient. The compound of the present invention can be used as treatment agents for allergic diseases mediated by mast cells based on a mechanism of blocking a MKKs-MAPKs signaling pathway. COPYRIGHT KIPO 2018 ...

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Номер записи: 27
04-05-2017 дата публикации

철 촉매 및 염기 첨가제를 이용한 4-치환 쿠마린 유도체의 제조방법

Номер: KR0101731952B1
Автор: 이구연, 윤지희, 박정민, 김재현, 추경호, 이준영
Принадлежит: 강원대학교산학협력단

... 본 발명은 철 촉매 및 염기 첨가제를 이용한 4-치환 쿠마린 유도체의 제조방법에 관한 것으로서, 4-치환 쿠마린 설파메이트를 출발물질로 하고, 이를 그리나드 시약과 커플링 반응을 통해 4-번 위치에 다양한 관능기를 갖는 4-치환 쿠마린 유도체를 짧은 시간에 부산물의 생성을 최소화하면서 높은 수율로 제조할 수 있는 방법에 관한 것이다.

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Номер записи: 28
25-07-2016 дата публикации

신규의 글루코키나제 활성화제 및 그의 제조방법

Номер: KR0101642097B1
Автор: 이원희, 한태동, 이구연, 김영환, 정은혜, 이동훈, 박유회, 민경난, 김재규, 이병규
Принадлежит: 주식회사유한양행

... 본 발명은 분자내에 스틸벤(stilbene) 또는 1,2-디페닐에탄(1,2-diphenylethane)을 갖는 아마이드 유도체 또는 이의 염, 이들의 제조방법, 및 이들을 포함하는 약학 조성물을 제공한다. 본 발명에 따른 아마이드 유도체는 글루코키나제를 현저하게 활성화시킴으로써, 고혈당증(hyperglycemia) 및 당뇨병(diabete)과 같은 글루코키나제 매개 질환의 치료에 유용하게 적용될 수 있다.

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Номер записи: 29
06-02-2018 дата публикации

METHOD FOR PREPARING BREWED COFFEE HAVING ENHANCED PREFERENCE BASED ON ANALYSIS OF AROMA CONSTITUENT

Номер: KR1020180012478A
Автор: LEE, KOO YEON, HWANG, WOON SANG
Принадлежит:

The present invention is to provide a method for preparing brewed coffee treated in specific conditions through a distribution step, an extraction step and an aging step. According to a method for preparing brewed coffee treated in specific conditions, brewed coffee showing optimal preference by changed aroma constituent can be manufactured. So, the method can be usefully used as a mass production technology of producing brewed coffee with uniform quality in a field of preparing brewed coffee. COPYRIGHT KIPO 2018 ...

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Номер записи: 30
14-03-2017 дата публикации

비스무트/은 혼합촉매를 이용한 2-테트랄론 유도체의 제조방법

Номер: KR0101715303B1
Автор: 이구연, 이필호, 김재현, 박정민, 윤지희
Принадлежит: 강원대학교산학협력단

... 본 발명은 비스무트/은 혼합촉매를 이용한 2-테트랄론 유도체의 제조방법 에 관한 것으로, 비스무트/은 혼합촉매를 이용하여 간단하고 효율적으로 2-테트랄론 유도체를 제조방법에 관 한 것이다. 상기 제조방법은 비스무트/은 혼합촉매를 이용함에 따라 짧은 시간에 고수율로 목적물질을 얻을 수 있고, 이때 제조된 2-테트랄론 유도체는 의약품 및 천연물의 중간체 합성에 이용될 수 있다.

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Номер записи: 31
30-06-2016 дата публикации

ANTIOXIDATIVE OR WHITENING COSMETIC COMPOSITION CONTAINING FERMENTED EXTRACT OF MISTLETOE

Номер: KR101634668B1
Автор: LEE, KOO YEON, CHOE, MYEON, PARK, CHUL SUN
Принадлежит: KNU-INDUSTRY COOPERATION FOUNDATION

Provided is an antioxidative or whitening cosmetic composition containing a fermented extract of mistletoe. The composition containing the fermented extract of mistletoe exhibits increased antioxidant efficacy and superoxide dismutase (SOD)-like activity than an unfermented extract of mistletoe. In addition, the total flavonoid content increases in the composition, and an increase in the tyrosinase inhibiting activity in an enzymatic level (the evaluation index for whitening effects) has been detected in a cellular level. Thus, the composition of the present invention can be useful as the antioxidative or whitening cosmetic composition. COPYRIGHT KIPO 2016 (AA) General mistletoe (BB) Fermented mistletoe (CC) Measurement after 2 minutes reaction 1mg/mL (DD) Measurement after 2 minutes reaction 2.5mg/mL (EE) Measurement after 2 minutes reaction 5mg/mL (FF) Measurement after 2 minutes reaction 10mg/mL ...

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Номер записи: 32
09-03-2018 дата публикации

폴리페놀 함량이 증대된 기능성 더치 커피의 제조방법

Номер: KR0101836994B1
Автор: 이구연, 황운상
Принадлежит: 강원대학교산학협력단

... 본 발명은 아로니아 추출물을 포함하는 아로니아 추출물 첨가 더치 커피를 제공한다. 본 발명의 아로니아 추출물 첨가 더치 커피는 항산화능, 총 폴리페놀 함량 및 총 플라보노이드 함량이 증가하였고, 카페인 함량이 감소한 것으로 나타나, 다양한 향과 풍미를 추구하는 소비자의 기호성을 충족시킬 수 있을 뿐만 아니라, 건강에 유익한 생리활성 물질이 증대된 더치 커피 제품의 생산을 가능하게 하므로, 커피 제조 분야에서 폴리페놀 함량이 증대된 기능성 더치 커피로서 유용하게 사용될 수 있다.

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Номер записи: 33
12-11-2015 дата публикации

TELE-HEALTHCARE METHOD BASED ON HL7 STANDARDS FOR INTEROPERABILITY AND SYSTEM THEREOF

Номер: KR101568610B1
Автор: LEE, KU YEON, KANG, KYUNG TAE
Принадлежит: INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS

Provided are a tele-healthcare method based on HL7 standards for interoperability and a system thereof. According to an aspect, the tele-healthcare method based on HL7 standards for interoperability provided by the present invention comprises the following steps of: enabling a mobile terminal to receive biometric data of a user measured by a personal health device; converting the measured biometric data into an HL7 format message through an HL7 interface of the mobile terminal; transmitting, storing, and managing the biometric data to a server wherein the biometric data is converted into the HL7 format message; and sharing the biometric data between hospital systems using an HL7 standard format as a reference wherein the biometric data is stored and managed in the server, thereby enabling a medical team to remotely diagnose a condition of a patient and prescribe medicine. COPYRIGHT KIPO 2016 (114) Blue tooth (123) HL7 interface (123a) Data loader (123b) Message generation unit (123c) Message ...

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Номер записи: 34
04-01-2018 дата публикации

ANTIOXIDANT OR WHITENING COSMETIC COMPOSITION COMPRISING SOLVENT FRACTION OF LORANTHUS TANAKAE EXTRACT AND ACTIVE MATERIALS ISOLATED THEREFROM

Номер: KR1020180001325A
Автор: LEE, KOO YEON, PARK, CHUL SUN
Принадлежит:

The present invention provides an ethyl acetate fraction or a butanol fraction isolated from a Loranthus tanakae extract; and an antioxidant or whitening cosmetic composition comprising active materials isolated therefrom. The composition comprising a specific solvent fraction or the active materials isolated therefrom exhibits excellent antioxidant and whitening activity and can be usefully used as a cosmetic composition for antioxidant or whitening use. COPYRIGHT KIPO 2018 ...

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Номер записи: 35