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Применить Всего найдено 47. Отображено 47.
13-04-2018 дата публикации

신규한 1,2-벤조티아진 유도체 및 이의 제조방법

Номер: KR0101848603B1
Автор: 이필호, 손정유
Принадлежит: 강원대학교산학협력단

... 본 발명은 1,2-벤조티아진 유도체 및 이의 제조방법에 관한 것으로, 본 발명의 1,2-벤조티아진 유도체 제조방법은 트리스(아세토나이트릴)펜타메틸사이클로펜타다이에닐 로듐(III) 헥사플루오로안티모네이트 촉매 및 염기 존재하에 술폭사민 유도체 및 트리아졸 유도체를 반응시켜 1,2-벤조티아진 유도체를 제조하는 단계를 포함한다.

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Номер записи: 1
02-08-2017 дата публикации

PRODUCTION METHOD OF CHIRAL BETA-AMINO ACID DERIVATIVE BY ASYMMETRIC HYDROGENATION REACTION USING CINCHONA-DERIVED ORGANIC CATALYST

Номер: KR101764185B1
Автор: LEE, PHIL HO, LEE, KOO YEON, UM, KYU SIK, KIM, CHEOL EUI
Принадлежит: KNU-INDUSTRY COOPERATION FOUNDATION

The present invention provides a production method of a chiral beta-amino acid derivative by an asymmetric hydrogenation reaction using a cinchona-derived organic catalyst. The production method of a chiral beta-amino acid derivative of the present invention can be used as a production method of a chiral compound, and a method synthesizing an optically high-purity compound in an ezetimibe synthesis field. COPYRIGHT KIPO 2017 ...

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Номер записи: 2
29-09-2017 дата публикации

N-IMIDOYL SULFOXIMINE DERIVATIVES AND PREPARATION METHOD THEREOF

Номер: KR1020170109274A
Автор: LEE, PHIL HO, CHOI, WON SEOK
Принадлежит:

The present invention relates to novel N-imidoyl sulfoximine derivatives capable of being used in various research fields by having important structural properties used as ligands and chiral adjuvants, and a preparation method thereof and, more specifically, to a method for preparing N-imidoyl sulfoximine derivatives having carbon-nitrogen coupling functional groups introduced in nitrogen atoms of sulfoximines by conducting reaction of alkyne derivatives, azide derivatives and N-sulfoximine derivatives in the presence of copper catalyst and N-imidoyl sulfoximine derivatives manufactured thereby. COPYRIGHT KIPO 2017 ...

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Номер записи: 3
01-07-2016 дата публикации

NOVEL N-(2-(AZULEN-1-YL)-2-SUBSTITUTED VINYL)-SULFONAMIDE DERIVATIVES AND PREPARATION THEREOF

Номер: KR1020160076753A
Автор: LEE, PHIL HO, PARK, SANG JUNE
Принадлежит:

The present invention relates to a novel N-(2-(azulen-1-yl)-2-substituted vinyl)-sulfonamide derivative and a method for preparing the same. The method for preparing a N-(2-(azulen-1-yl)-2-substituted vinyl)-sulfonamide derivative according to the present invention has an advantage in that it produces only nitrogen gas as a byproduct through the reaction with a sulfone group-containing triazole derivative in the presence of a rhodium (II) catalyst. In addition, the method provides a N-(2-(azulen-1-yl)-2-substituted vinyl)-sulfonamide derivative with high yield. COPYRIGHT KIPO 2016 ...

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Номер записи: 4
05-03-2018 дата публикации

INDOLO-1,2-BENZOTHIAZINE DERIVATIVE AND PRODUCTION METHOD THEREOF

Номер: KR101834228B1
Автор: LEE, PHIL HO, KO, GI HOON
Принадлежит: KNU-INDUSTRY COOPERATION FOUNDATION

The present invention relates to an indolo-1,2-benzothiazine derivative and a production method thereof. More specifically, the present invention relates to a method for efficiently producing the indolo-1,2-benzothiazine derivative by undergoing a cyclization reaction using a sulfoximine derivative and a 3-diazoindoline-2-imine derivative in the presence of a rhodium catalyst, a ligand and an additive. The present invention further relates to an indolo-1,2-benzothiazine derivative produced thereby. COPYRIGHT KIPO 2018 ...

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Номер записи: 5
17-06-2016 дата публикации

NOVEL BENZO[D][1,2]OXAPHOSPHORINE DERIVATIVES AND METHOD FOR PREPARING SAME

Номер: KR101631513B1
Автор: LEE, PHIL HO, SHIN, SEO HYUN, JEONG, YEON SEOK, JEON, WOO HYUNG
Принадлежит: KNU-INDUSTRY COOPERATION FOUNDATION

The present invention relates to a novel benzo[d][1,2]oxaphosphorine derivative and a method for preparing the same. The benzo[d][1,2]oxaphosphorine derivative according to the present invention can be used as an important starting material or an intermediate applicable to a pharmaceutical industry and a crop protection industry by virtue of its physiological activity. In addition, the method for preparing a benzo[d][1,2]oxaphosphorine derivative according to the present invention comprises a step of carrying out carbon-hydrogen bond activation reaction of a benzyl phosphinic acid derivative by using a transition metal catalyst to form carbon-carbon and carbon-oxygen bonds with carbon monoxide. Thus, the method is advantageous in that various benzo[d][1,2]oxaphosphorine derivatives can be obtained in a one-pot process with high yield and low cost. COPYRIGHT KIPO 2016 ...

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Номер записи: 6
08-10-2018 дата публикации

레벨 쉬프트 회로

Номер: KR0101905502B1
Автор: 이필호, 장영찬, 이현배, 이광훈
Принадлежит: 에스케이하이닉스 주식회사, 금오공과대학교 산학협력단

... 본 발명은 레벨 쉬프트부와 등화부를 구비하는 레벨 쉬프트 회로를 제공한다. 레벨 쉬프트부는 외부로부터 입력되는 신호의 전압 레벨을 다른 크기의 전압 레벨로 변환한다. 등화부는 레벨 쉬프트부의 고주파 증폭율을 증가시켜서 노이즈를 감소시킨다.

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Номер записи: 7
10-10-2017 дата публикации

METHOD FOR PREPARING NOVEL PYRIDO ISOINDOLE DERIVATIVES

Номер: KR1020170109709A
Автор: LEE, PHIL HO, KIM, CHEOL EUI, BAEK, YONG HYEON
Принадлежит:

The present invention relates to a method for preparing novel pyrido isoindole derivatives, which can be used as a main skeleton structure used in various fields such as pharmaceuticals, natural products, fluorescent substances and dyeing materials, and provides a method for preparing novel pyrido isoindole derivatives, which is effective and more easy by obtaining pyrido isoindole derivatives from diazoacetates in the presence of a copper catalyst or only by heating without a copper catalyst using carbene derivatives which can react with various nucleophiles. The present invention also provides an efficient method for preparing pyrido isoindole derivatives, in which diazotization is performed by using a basic catalyst and azide derivatives to acetate derivatives, and performing an intramolecular cyclization reaction through a removal reaction of nitrogen under Cu(OTf)_2 in one-pot. COPYRIGHT KIPO 2017 ...

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Номер записи: 8
06-09-2017 дата публикации

CLOCK SIGNAL GENERATION CIRCUIT HAVING FREQUENCY SYNTHESIZER

Номер: KR101775636B1
Автор: JANG, YOUNG CHAN, SHIN, SEUNG HUN, LEE, PIL HO
Принадлежит: KUMOH NATIONAL INSTITUTE OF TECHNOLOGY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

The present invention relates to a clock signal generation circuit having a frequency synthesizer. The clock signal generation circuit prevents that a normal counter operation is impossible since a current clock signal and a rising section of a next clock signal are combined due to a big logic delay value when a large phase shift with respect to a multiphase clock signal occurs at one time when generating the multiphase clock signal by using an open loop fractional frequency divider using a frequency divider based on a multiphase output and a counter. COPYRIGHT KIPO 2017 (200) Dump circuit (210) First counter (220) Decoder (240) Second counter (250) Interpolation circuit (260) Third counter (280) First divider (290) Second divider ...

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Номер записи: 9
11-11-2016 дата публикации

신규한 벤조옥사포스피닌 옥사이드 유도체 및 이의 제조방법

Номер: KR0101675513B1
Автор: 이필호, 전우형, 손정유
Принадлежит: 강원대학교산학협력단

... 본 발명은 신규한 구조의 벤조옥사포스피닌 옥사이드(benzooxaphosphinine oxide) 유도체 및 이의 제조방법에 관한 것으로, 보다 구체적으로 본 발명의 벤조옥사포스피닌 옥사이드 유도체는 포스파아이소쿠마린(phosphaisocoumarin) 유도체 및 포스파아이소크로마논(phosphaisochromanone) 유도체를 포함한다. 본 발명에 따른 벤조옥사포스피닌 옥사이드 유도체는 약리 활성 및 생리 활성을 가지고 있어 제초제 등과 같은 농약 뿐만 아니라, 다양한 의약품 합성의 중요한 중간체로 이용될 수 있다. 또한, 본 발명에 따른 벤조옥사포스피닌 옥사이드 유도체의 제조방법은 팔라듐(Pd) 촉매와 은(Ag) 산화제 존재 하에 각각의 아릴 포스포닉 산 유도체 또는 아릴메틸 포스포닉 산 유도체와 바이닐 유도체와의 분자간 C-H 올레핀화/고리화 반응에 의해 다양한 벤조옥사포스피닌 옥사이드 유도체를 효율적으로 합성할 수 있다.

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Номер записи: 10
03-01-2014 дата публикации

NOVEL PHOSPHOROUS 2-PYRONE DERIVATIVE AND PREPARATION METHOD THEREOF

Номер: WO2014003467A1
Автор: LEE, Phil Ho, MO, Jun tae, RYU, Taekyu
Принадлежит:

The present invention relates to a novel phosphorous 2-pyrone derivative and a preparation method thereof. The phosphorus 2-pyrone derivative, according to the present invention, can be synthesized efficiently by treating an alkyl hydrogen alkynylphosphonate derivative and an alkyne derivative with a minimal amount of a gold catalyst.

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Номер записи: 11
26-12-2017 дата публикации

METHOD FOR PRODUCING 5,N-FUSED THIOPHENE COMPOUND AND 5,N-FUSED THIOPHENE

Номер: KR101811193B1
Автор: LEE, PHIL HO, KIM, JI EUN, LEE, JIN SUB, YUN, HYUN SIK, BAEK, YONG HYEON
Принадлежит: KNU-INDUSTRY COOPERATION FOUNDATION

The present invention relates to a method for producing a 5,n-fused thiophene compound capable of being used in various investigation such as functional material science including solar cell polymers as well as drugs. The present invention further relates to a novel 5,n-fused thiophene compound. More specifically, the present invention relates to a method for efficiently producing a 5,n-fused thiophene compound through an intramolecular trans-cyclization reaction using an alkynyl thiadiazole compound in the presence of a rhodium catalyst and a ligand. The present invention further relates to a 5,n-fused thiophene compound produced thereby. COPYRIGHT KIPO 2018 ...

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Номер записи: 12
06-07-2016 дата публикации

NOVEL BENZOOXAPHOSPHININE OXIDE DERIVATIVE AND METHOD FOR PREPARING SAME

Номер: KR1020160079315A
Автор: LEE, PHIL HO, JEON, WOO HYUNG, SON, JEONG YU
Принадлежит:

The present invention relates to a benzooxaphosphinine oxide derivative having a novel structure and a method for preparing the same. More particularly, the benzooxaphosphinine oxide derivative according to the present invention includes a phosphaisocoumarin derivative and a phosphaisochromanone derivative. The benzooxaphosphinine oxide derivative according to the present invention has pharmacological and physiological activities, and thus can be used as an important intermediate for the synthesis of agricultural chemicals, such as herbicides, and various pharmaceuticals. In addition, the method for preparing a benzooxaphosphinine oxide derivative according to the present invention can provide various benzooxaphosphinine oxide derivatives efficiently through intermolecular C-H olefination/cyclization of each aryl phosphonic acid derivative or arylmethyl phosphonic acid derivative with a vinyl derivative in the presence of a palladium (Pd) catalyst and a silver (Ag) oxidant. COPYRIGHT KIPO ...

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Номер записи: 13
26-06-2018 дата публикации

DIHYDROTHIOPHENE DERIVATIVE, THIOPHENE DERIVATIVE, AND PRODUCTION METHOD THEREOF

Номер: KR1020180070255A
Автор: LEE, PHIL HO, SON, JEONG YU, KIM, JONG HYE, HAN, SANG HOON
Принадлежит:

The present invention relates to a trisubstituted dihydrothiophene derivative, a trisubstituted thiophene derivative, and a production method thereof. More specifically, the method for producing the trisubstituted dihydrothiophene derivative and the trisubstituted thiophene derivative is very efficient in obtaining the dihydrothiophene derivative and the thiophene derivative with high regioselectivity and yield by undergoing an intermolecular cyclization in the presence of a chloro(1,5-cyclooctadiene)rhodium (I) dimer catalyst and 1,1′-bis(diphenylphosphino)ferrocene. COPYRIGHT KIPO 2018 ...

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Номер записи: 14
21-11-2016 дата публикации

신규한 피라진 유도체 및 이의 제조방법

Номер: KR0101677599B1
Автор: 이필호, 유태규, 백용현
Принадлежит: 강원대학교산학협력단

... 본 발명은 신규한 피라진 유도체 및 이의 제조방법에 관한 것이으로, 본 발명의 신규한 피라진 유도체는 천연물에서 많이 존재하는 피라진 모핵에 다양한 치환체를 가지고 있어 의약 및 농약 등의 분야에서 중요한 원료물질 또는 중간체로 이용될 수 있다. 또한, 본 발명에 따른 피라진 유도체 제조방법은 로듐(Il) 촉매 존재 하에 2H-아지린 유도체와 N-설포닐 트리아졸 유도체 사이의 [3+3] 고리화 반응을 통해 높은 수율과 간단한 실험과정으로 피라진 유도체를 합성하는 장점을 지닌다.

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Номер записи: 15
05-03-2018 дата публикации

PRODUCTION METHOD OF ISOTHIAZOLE DERIVATIVE

Номер: KR101834224B1
Автор: LEE, PHIL HO, SEO, BO RAM, KIM, YA GOB
Принадлежит: KNU-INDUSTRY COOPERATION FOUNDATION

The present invention relates to a production method of an isothiazole derivative. More specifically, the production method of the isothiazole derivative of the present invention which can obtain 3-substituted isothiazole derivatives by intermolecular cyclization reaction or 3,4-linked isothiazole derivatives by intramolecular cyclization reaction in the presence of a chloro(1,5-cyclooctadiene)rhodium(I)dimer catalyst and 1,1′-bis(diphenylphosphino)ferrocene, with high selectivity and yield in a very effective way. COPYRIGHT KIPO 2018 ...

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Номер записи: 16
24-05-2016 дата публикации

NOVEL FLUORENE DERIVATIVE AND METHOD FOR PRODUCING SAME

Номер: KR101623704B1
Автор: LEE, PHIL HO, SEO, BO RAM, JEON, WOO HYUNG
Принадлежит: KNU-INDUSTRY COOPERATION FOUNDATION

The present invention relates to a novel effective fluorene derivative represented by chemical formula 1 and capable of being used as an organic electronic material and a bioactive substance, and a method for producing the same. In chemical formula 1, L, R^1, R^2, R^3, R^6, and R^7 are the same as defined in the detailed descriptions of the present invention. COPYRIGHT KIPO 2016 ...

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Номер записи: 17
30-06-2015 дата публикации

Novel enol silyl ether derivative and its preparation method

Номер: KR0101532564B1
Автор: 이필호, 강동진, 이의철, 박상준
Принадлежит: 강원대학교산학협력단

... 본 발명은 신규한 엔올 실릴 이서 유도체 및 이의 제조방법에 관한 것으로 본 발명의 신규한 엔올 실릴 이서 유도체는 탄소-탄소 결합형성에 매우 중요한 화합물로 사용될 수 있으며, 본 발명에 따른 엔올 실릴 이서 유도체의 제조방법은 온화한 조건에서 간단한 공정으로 높은 수율로 엔올 실릴 이서 유도체를 얻을 수 있다.

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Номер записи: 18
25-05-2017 дата публикации

NOVEL SYNTHESIS METHOD OF CINNOLIN-3(2H)-ONE DERIVATIVE USING RHODIUM CATALYST

Номер: KR101740155B1
Автор: KIM, IN SU, LEE, PHIL HO
Принадлежит: RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY, KNU-INDUSTRY COOPERATION FOUNDATION

The present invention relates to a novel synthesis method of cinnolin-3(2H)-one derivatives using a rhodium catalyst, and more specifically, to a synthesis method in which cinnolin-3(2H)-one derivatives are synthesized through reaction between an azobenzene derivative and 5-diazo-2,2-dimethyl-1,3-dioxane-4,6-dione in the presence of a rhodium catalyst. According to the synthesis method of the present invention, by activating the inactive C-H bond of azobenzene, which is a biologically important compound, cinnolin-3(2H)-one derivatives with various substituents can be synthesized more easily and efficiently compared to conventional methods. COPYRIGHT KIPO 2017 ...

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Номер записи: 19
03-07-2015 дата публикации

NOVEL 2-VINYLPHENYL PHOSPHATE DERIVATIVE COMPOUND AND METHOD FOR PRODUCING SAME

Номер: KR1020150075156A
Автор: LEE, PHIL HO, RYU, TAE KYU, KIM, SUNG GAK, CHAN LI YAN
Принадлежит:

The present invention provides a 2-vinylphenyl phosphate derivative compound and a method for effectively producing the same, wherein the 2-vinylphenyl phosphate derivative compound has various structures through a reaction with a vinyl compound by activating a C-H bond in a desired position of phenyl phosphate by using a palladium catalyst and an additive. Moreover, the 2-vinylphenyl phosphate derivative compound can be not only used as a basic structure of a natural material but also developed into novel medicines and various medicine and medical supplies. COPYRIGHT KIPO 2015 ...

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Номер записи: 20
05-01-2018 дата публикации

NOVEL 1,2-BENZOTHIAZINE DERIVATIVES AND MANUFACTURING METHOD THEREOF

Номер: KR1020180001784A
Автор: LEE, PHIL HO, SON, JEONG YU
Принадлежит:

The present invention relates to novel 1,2-benzothiazine derivatives and to a manufacturing method thereof, wherein the method for manufacturing the 1,2-benzothiazine derivatives of the present invention comprises a step for reacting a sulfoximine derivative and a triazole derivative in the presence of a tris (acetonitrile) pentamethylcyclopentadienyl rhodium (III) hexafluoroantimonate catalyst and a base to manufacture the 1,2-benzothiazine derivatives. The 1,2-benzothiazin derivatives of the present invention can be used variously in raw materials or intermediates for new drugs, bios, and the like. COPYRIGHT KIPO 2018 ...

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Номер записи: 21
16-07-2015 дата публикации

METHOD FOR PREPARING 2-TETRALONE DERIVATIVE USING BISMUTH/SILVER MIXED CATALYST

Номер: KR1020150083031A
Автор: LEE, KOO YEON, LEE, PHIL HO, KIM, JAE HYUN, PARK, JUNG MIN, YUN, JI HEE
Принадлежит:

The present invention relates to a method for preparing a 2-tetralone derivative using a bismuth/silver mixed catalyst in a simple and efficient manner. According to the method, a target material can be obtained within short time as the bismuth/silver mixed catalyst is used. The 2-tetralone derivative, prepared by the method, can be used to synthesize pharmaceutical products and intermediates of natural materials. The 2-tetralone derivative is represented by Chemical formula 1. COPYRIGHT KIPO 2015 ...

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Номер записи: 22
08-01-2016 дата публикации

Method for Culturing Fruits Having the High Content of Calcium and the Fruits Obtained Thereby

Номер: KR0101582533B1
Автор: 배동규, 심재일, 신주철, 이필호
Принадлежит: 다산그린 주식회사, 농업회사법인 주식회사 에스아그로

... 본 발명은 칼슘 함량 강화 과일의 재배 방법 및 이 방법에 의하여 얻어진 칼슘 함량 강화 과일을 개시한다. 본 발명의 칼슘 함량 강화 과일의 재배 방법은 질산칼슘과 말산을 고온·고압하에서 반응시켜 얻어진 반응 결과물 또는 이러한 반응 결과물로부터 얻어진 말산과 칼슘 결합 화합물을 이용함을 특징으로 한다.

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Номер записи: 23
05-09-2016 дата публикации

신규한 벤즈아자포스폴-3-온 1-옥사이드 유도체와 이의 제조방법

Номер: KR0101653991B1
Автор: 이필호, 김예린
Принадлежит: 강원대학교산학협력단

... 본 발명은 새로운 벤즈아자포스폴-3-온 1-옥사이드 유도체 및 이의 제조방법에 관한 것이다. 본 발명에 따른 벤즈아자포스폴-3-온 1-옥사이드 유도체의 제조방법은 산화제와 할로겐계 첨가제 존재 하에 출발물질인 포스폰아마이드 유도체의 분자내 산화성 탄소-질소 결합 반응을 통해 선택적으로 벤즈아자포스폴-3-온 1-옥사이드 유도체를 합성하는 것을 특징으로 한다.

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Номер записи: 24
06-07-2016 дата публикации

NOVEL BENZAZAPHOSPHOL-3-ONE 1-OXIDE DERIVATIVES AND MANUFACTURING METHOD THEREOF

Номер: KR1020160079316A
Автор: LEE, PHIL HO, KIM, YEA RIN
Принадлежит:

The present invention relates to novel benzazaphosphol-3-one 1-oxide derivatives and a manufacturing method thereof. According to the present invention, the manufacturing method of the benzazaphosphol-3-one 1-oxide derivatives selectively synthesizes the benzazaphosphol-3-one 1-oxide derivatives through an oxidative carbon-nitrogen binding reaction of phosphonamide derivatives as a starting material, in the presence of an oxidizing agent and a halogen-based additive. According to the present invention, the benzazaphosphol-3-one 1-oxide derivatives exhibit physiological activities, and can be used in the pharmaceutical industry. COPYRIGHT KIPO 2016 ...

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Номер записи: 25
23-05-2017 дата публикации

METHOD FOR PREPARING NOVEL PYRIDO ISO QUINOLINONE DERIVATIVES

Номер: KR1020170056081A
Автор: LEE, PHIL HO, BAEK, YONG HYEON, JEON, BONG KEUN
Принадлежит:

The present invention relates to a method for preparing pyrido iso quinolinone derivatives represented by the following chemical formula 1. In the chemical formula 1, A ring, B ring, R^1, R^2, R^3, a, and b are the same as defined respectively in detailed description of the invention. The pyrido iso quinolinone derivatives according to the present invention are conjugation polyhedral ring compounds, having a variety of electron, photoelectron and magnetic properties. COPYRIGHT KIPO 2017 ...

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Номер записи: 26
06-07-2016 дата публикации

NOVEL BENZOTRIAZOLE DERIVATIVE AND PRODUCING METHOD THEREOF

Номер: KR1020160079559A
Автор: LEE, PHIL HO, RYU, TAE KYU, MIN, JI AE
Принадлежит:

The present invention relates to a benzotriazole derivative represented by chemical formula 1, and to a producing method thereof. The benzotriazole derivative according to the present invention can be used in raw materials and intermediates of new drugs, a UV stabilizer, and an organic electron material. COPYRIGHT KIPO 2016 ...

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Номер записи: 27
31-07-2015 дата публикации

Novel preparation method of benzoxazole derivative

Номер: KR0101540623B1
Автор: 이필호, 김진식, 류태규, 김상혁, 유은정
Принадлежит: 강원대학교산학협력단

... 본 발명은 하기 화학식 1로 표시되는 알키닐레이션(alkynylation) 된 벤즈옥사졸(benzoxazole) 유도체의 제조방법에 관한 것으로, 보다 상세하게는, 팔라듐 촉매, 포스핀계 리간드로 1,3-bis(diphenylphosphino)propane 존재 하에서 은염(silver salt), 프로피올릭 산(propiolic acid) 및 벤즈옥사졸 화합물을 반응시켜 알키닐레이션(alkynylation) 된 벤즈옥사졸 유도체의 제조방법에 관한 것이다.

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Номер записи: 28
26-07-2017 дата публикации

신규한 피리도아이소퀴놀리논 유도체의 제조방법

Номер: KR0101761200B1
Автор: 이필호, 백용현, 전봉근
Принадлежит: 강원대학교산학협력단

... 본 발명은 하기 화학식 1로 표시되는 피리도아이소퀴놀리논 유도체의 제조방법에 관한 것이다. [화학식 1] 상기 화학식 1에서, A 고리, B 고리, R1, R2, R3, a 및 b는 각각 발명의 상세한 설명에서 정의한 바와 같다.

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Номер записи: 29
06-04-2018 дата публикации

신규한 피리도아이소인돌 유도체의 제조방법

Номер: KR0101845935B1
Автор: 이필호, 김철의, 백용현
Принадлежит: 강원대학교산학협력단

... 본 발명은 약학, 천연물, 형광 물질, 염색 물질과 같은 다양한 분야에서 사용되는 주요 골격 구조로 이용될 수 있는 피리도아이소인돌 유도체의 제조방법에 관한 것으로, 다양한 친핵체와 반응 할 수 있는 카벤 유도체를 이용하여 다이아조아세테이트로부터 구리촉매 존재 하에 또는 구리촉매 없이 가열만을 통해 효과적이고 보다 용이하게 피리도아이소인돌 유도체의 제조방법을 제공한다. 또한 아세테이트 유도체에 염기성 촉매, 아지드 유도체를 사용하여 diazotization을 진행한 후 Cu(OTf)2 촉매하에 질소의 제거반응을 통한 분자내 고리화 반응을 one-pot으로 진행 시켜 피리도인돌유도체의 효율적인 제조방법을 제공한다.

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Номер записи: 30
25-01-2017 дата публикации

LEVEL SHIFT CIRCUIT

Номер: KR1020170009181A
Автор: LEE, PIL HO, JANG, YEONG CHAN, LEE, HYUN BAE, LEE, KWANG HUN
Принадлежит:

The present invention provides a level shift circuit comprising a level shift part and an equalizing part. The level shift part converts the voltage level of a signal inputted from the outside into a voltage level of a different magnitude. The equalizing part increases the high-frequency amplification factor of the level shifter, thereby reducing noise. So, the integrity of an output signal can be improved. COPYRIGHT KIPO 2017 (111) Equalizing part (121) Level shift part (131) Switching part ...

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Номер записи: 31
27-02-2017 дата публикации

신규한 바이닐 포스파쿠마린 유도체 및 이의 제조방법

Номер: KR0101710697B1
Автор: 이필호, 김철의
Принадлежит: 강원대학교산학협력단

... 본 발명은 약리활성 및 생리활성을 가지고 있어 의약 및 농약 등의 분야에서 중유한 원료물질 또는 중간체로 이용될 수 있는 신규한 바이닐 포스파쿠마린의 유도체 및 이의 제조방법에 관한 것이다.

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Номер записи: 32
18-10-2018 дата публикации

디하이드로티오펜 유도체, 티오펜 유도체 및 이들의 제조방법

Номер: KR0101909199B1
Автор: 이필호, 손정유, 김종혜, 한상훈
Принадлежит: 강원대학교산학협력단

... 본 발명은 3-치환된 디하이드로티오펜 유도체, 3-치환된 티오펜 유도체 및 이들의 제조방법에 관한 것으로, 보다 상세하게 본 발명의 3-치환된 디하이드로티오펜 유도체 및 3-치환된 티오펜 유도체의 제조방법은 클로로(1,5-시클로옥타디엔)로듐(Ⅰ)다이머 촉매 및 1,1'-비스(디페닐포스피노)페로센존재하에 분자간 고리화반응으로 높은 위치선택성 및 수율로 디하이드로티오펜 유도체 및 티오펜 유도체를 얻을 수 있는 매우 효율적인 방법이다.

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Номер записи: 33
06-07-2016 дата публикации

PYRROLE DERIVATIVE AND PRODUCING METHOD THEREOF

Номер: KR1020160079560A
Автор: LEE, PHIL HO, KIM, CHEOL EUI, PARK, YOUNG CHUL, PARK, SANG JUNE
Принадлежит:

The present invention relates to a pyrrole derivative represented by chemical formula 1, and a producing method thereof. The pyrrole derivative is used in natural materials and bioactive materials and can be used in raw materials or intermediates. COPYRIGHT KIPO 2016 ...

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Номер записи: 34
07-03-2017 дата публикации

PRODUCTION METHOD OF 2H-INDAZOLE DERIVATIVE

Номер: KR101713303B1
Автор: LEE, PHIL HO, YONG, WOO SOON, YOON, HYUN SIK
Принадлежит: KNU-INDUSTRY COOPERATION FOUNDATION

The present invention relates to a production method of a 2H-indazole derivative represented by chemical formula 1, which can simply produce the 2H-indazole derivative. In the chemical formula 1, R^1, R^2, R^3 and R are respectively the same as defined in the detailed description of the present invention. COPYRIGHT KIPO 2017 ...

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Номер записи: 35
31-05-2017 дата публикации

NOVEL N-IMIDAZOLYL SULFOXIMINE DERIVATIVES AND SYNTHESIS METHOD THEREOF

Номер: KR101742226B1
Автор: LEE, PHIL HO, KIM, SANG HYUCK, KIM, JI EUN, LEE, JIN SUB
Принадлежит: KNU-INDUSTRY COOPERATION FOUNDATION

The present invention relates to a novel N-imidazolyl sulfoximine derivative represented by chemical formula 1, and a synthesis method thereof, and more specifically, to an N-imidazolyl sulfoximine derivative which is synthesized using an N-cyano sulfoximine derivative represented by chemical formula 2 as a starting material; and to a synthesis method thereof. In the chemical formulas 1 and 2, R^1, R^2, R^3, R^4, and R^5 are as defined in the specification of the present invention. COPYRIGHT KIPO 2017 ...

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Номер записи: 36
04-07-2018 дата публикации

ARITHMETIC CODE GENERATION CIRCUIT AND DIGITAL CORRECTION CIRCUIT INCLUDING SAME

Номер: KR1020180075198A
Автор: JANG, YOUNG CHAN, LEE, PIL HO, LEE, KWANG HUN, LEE, HYUN BAE
Принадлежит:

The present invention relates to an arithmetic code generation circuit for performing a calibration by using a counter and a digital correction circuit including the same. The arithmetic code generation circuit performs that two digital codes determined in a first condition and a second condition are sampled and calculated, and are stored as arithmetic codes having a medium value by corresponding to a first mode and a second mode. Also, the arithmetic code generation circuit re-calculates the arithmetic codes and resolves comparative performance or a comparison offset influence of a comparator, thereby resolving an error of the calibration. The digital correction circuit comprises: a comparison circuit; a count code generation circuit; the arithmetic code generation circuit; and a code selection circuit. COPYRIGHT KIPO 2018 ...

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Номер записи: 37
31-03-2023 дата публикации

아줄렌 화합물 및 이의 제조방법

Номер: KR102516732B1
Автор: 이필호, 손정유
Принадлежит: 강원대학교산학협력단

... 본 본 발명은 의약화학, 재료화학 등의 다양한 분야에서 중요 원료물질 또는 중간체로서 유용하게 이용될 수 있는 다중고리 화합물인 아줄렌, 구체적으로 아줄레노락톤 및 아줄레노락탐 화합물 및 이의 제조방법에 관한 것이다.

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Номер записи: 38
14-03-2017 дата публикации

비스무트/은 혼합촉매를 이용한 2-테트랄론 유도체의 제조방법

Номер: KR0101715303B1
Автор: 이구연, 이필호, 김재현, 박정민, 윤지희
Принадлежит: 강원대학교산학협력단

... 본 발명은 비스무트/은 혼합촉매를 이용한 2-테트랄론 유도체의 제조방법 에 관한 것으로, 비스무트/은 혼합촉매를 이용하여 간단하고 효율적으로 2-테트랄론 유도체를 제조방법에 관 한 것이다. 상기 제조방법은 비스무트/은 혼합촉매를 이용함에 따라 짧은 시간에 고수율로 목적물질을 얻을 수 있고, 이때 제조된 2-테트랄론 유도체는 의약품 및 천연물의 중간체 합성에 이용될 수 있다.

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Номер записи: 39
04-11-2016 дата публикации

신규한 벤조트리아졸 유도체 및 이의 제조방법

Номер: KR0101672729B1
Автор: 이필호, 유태규, 민지애
Принадлежит: 강원대학교산학협력단

... 본 발명은 벤조트리아졸 유도체 및 이의 제조 방법에 관한 것이다.

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Номер записи: 40
15-01-2019 дата публикации

3-(알케닐)인돌리진 화합물 및 이의 제조방법

Номер: KR0101938354B1
Автор: 이필호, 손정유, 백용현, 엄규식
Принадлежит: 강원대학교산학협력단

... 본 발명은 3-(알케닐)인돌리진 화합물 및 이의 제조방법에 관한 것으로, 보다 상세하게는 피리도트리아졸 화합물 및 1,3-디엔 화합물로부터 3-(알케닐)인돌리진 화합물을 원-팟으로 제조하는 방법 및 신규 3-(알케닐)인돌리진 화합물에 관한 것이다.

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Номер записи: 41
16-03-2023 дата публикации

아줄레노피리디논 화합물 및 이의 제조방법

Номер: KR102510279B1
Автор: 이필호, 한기욱
Принадлежит: 강원대학교산학협력단

... 본 본 발명은 의약화학, 재료화학 등의 다양한 분야에서 중요 원료물질 또는 중간체로서 유용하게 이용될 수 있는 다중고리 화합물인 아줄레노피리디논 화합물 및 이의 제조방법에 관한 것이다.

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Номер записи: 42
06-10-2016 дата публикации

신규한 N-(2-(아줄렌-1-일)-2-치환된바이닐)-설폰아마이드 유도체 및 이의 제조방법

Номер: KR0101663064B1
Автор: 이필호, 박상준
Принадлежит: 강원대학교산학협력단

... 본 발명은 하기 화학식 1로 표시되는 새로운 N-(2-(아줄렌-1-일)-2-치환된바이닐)-설폰아마이드 유도체 및 이의 제조방법에 관한 것이다. [화학식 1] 본 발명에 따른 N-(2-(아줄렌-1-일)-2-치환된바이닐)-설폰아마이드 유도체의 제조방법은 로듐(lI) 촉매 하에 설폰기를 포함하는 트리아졸 유도체와의 반응을 통해 부산물로써 질소 기체만을 배출한다는 장점을 지닐뿐만 아니라, 높은 수율로 N-(2-(아줄렌-1-일)-2-치환된바이닐)-설폰아마이드 유도체를 합성한다.

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Номер записи: 43
22-09-2016 дата публикации

NOVEL PYRAZINE DERIVATIVE AND PRODUCTION METHOD THEREOF

Номер: KR1020160110718A
Автор: LEE, PHIL HO, RYU, TAE KYU, BAEK, YONG HYEON
Принадлежит:

The present invention relates to a novel pyrazine derivative and a production method thereof. The novel pyrazine derivative of the present invention includes various substitution bodies on a pyrazine abundantly existing in natural substances and thus can be used as a raw material or an intermediate product in the production of drugs and agricultural pesticides. In addition, the method for producing the pyrazine derivative enables synthesis of the pyrazine derivative with a simple experiment process and also ensures high yield, via a [3+3] cyclization reaction between a 2H-azirine derivative and an N-sulfonyl triazole derivative in the presence of a rhodium (Il) catalyst. COPYRIGHT KIPO 2016 ...

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Номер записи: 44
29-03-2016 дата публикации

Novel 2-vinylphenyl phosphate derivatives and its preparation method

Номер: KR0101606347B1
Автор: 이필호, 유태규, 김성각, 찬리얀
Принадлежит: 강원대학교산학협력단

... 본 발명은 팔라듐 촉매와 첨가제를 사용하여 페닐 포스페이트의 원하는 위치의 C-H 결합을 활성화 하여 바이닐 화합물과의 반응을 통해 다양한 구조의 2-바이닐 페닐 포스페이트 유도체 화합물 및 효율적인 제조방법을 제공하였다. 또한 본 발명에 의해 제조 된 신규한 2-바이닐페닐 포스페이트 유도체 화합물은 천연물의 기본골격으로 사용될 뿐만 아니라 이를 통해 신약 개발 및 다양한 의약품의 개발이 가능하다.

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Номер записи: 45
21-05-2018 дата публикации

IMIDAZO [1,2-A] PYRIDINE-3-CARBOXYLATE DERIVATIVES AND PREPARATION METHOD THEREOF

Номер: KR0101859928B1
Автор: LEE, PHIL HO, PARK, SANG JUNE
Принадлежит: KNU-INDUSTRY COOPERATION FOUNDATION

The present invention relates to imidazo [1,2-a] pyridine-3-carboxylate derivatives and to a preparation method thereof, and more particularly, to a method for efficiently producing imidazo [1,2-a] pyridine-3-carboxylate derivatives by performing an aza-[3+2] ring addition reaction of α-diazo oxime ether derivative and a pyridine derivative in the presence of a copper (II) catalyst, and to the imidazo [1,2-a] pyridine-3-carboxylate derivatives prepared by the method. COPYRIGHT KIPO 2018 ...

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Номер записи: 46
21-09-2016 дата публикации

NOVEL VINYL PHOSPHACOUMARIN DERIVATIVE AND PRODUCING METHOD THEREOF

Номер: KR1020160109403A
Автор: LEE, PHIL HO, KIM, CHEOL EUI
Принадлежит:

The present invention relates to a novel vinyl phosphacoumarin derivative which can be used as an important raw material or an intermediate product in fields such as medicines and agriculture due to pharmacological activity and physiological activity, and a producing method thereof. The vinyl phosphacoumarin derivative is represented by chemical formula 1. COPYRIGHT KIPO 2016 ...

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Номер записи: 47