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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 31. Отображено 31.
22-08-2018 дата публикации

이동 단말기 및 그 동작 제어 방법

Номер: KR0101890674B1
Автор: 권아림, 이선아, 권윤미
Принадлежит: 엘지전자 주식회사

... 둘 이상의 연결된 연락처에 대하여 각각 차별화된 서비스를 제공함으로써, 편리하고 효율적인 연락처 관리 기능을 제공하는 이동 단말기. 이를 위해, 본 명세서에 개시된 일 실시 예에 따른 이동 단말기의 동작 제어 방법은 다수의 연락처를 포함하는 연락처 리스트를 표시하는 단계; 사용자 입력에 따라 상기 연락처 리스트에서 하나의 제1 연락처를 제1 수신자로 지정하는 단계; 상기 제1 연락처에 연결된 적어도 하나의 제2 연락처가 존재하는 경우, 상기 적어도 하나의 제2 연락처를 제2 수신자로 지정하는 단계; 및 상기 제1 수신자에 대하여 제1 동작을 수행하고, 상기 제2 수신자에 대하여 상기 제1 동작에 종속하는 제2 동작을 수행하는 단계를 포함한다.

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Номер записи: 1
29-06-2015 дата публикации

APPARATUS FOR DRYING UMBRELLA USING SELF-CIRCULATING HOT AIR

Номер: KR1020150071860A
Автор: LEE, SEUNG MYEONG, LEE, SUN A, KIM, DO HEE
Принадлежит:

An apparatus for drying an umbrella using self-circulating hot air is disclosed. As a driving motor (210) operates, a rotary bucket (200) which is spline combined to a rotary shaft (210a) of the driving motor (210) rotates, accordingly a blowing blade (300) also rotates together with the rotary bucket (200). Then a blowing of the wind by centrifugal force of the revolution of the rotary bucket (200) operates systematically, thereby self-circulating the wind in the following sequence of directions; an inner part of the rotary bucket (200) -> a discharging hole (230) -> a lower space of a dual wall structure -> a heating unit (400) -> an upper space of a dual wall structure -> an injecting hole (130) -> a through-window (240) -> an inner part of the rotary bucket (200), and in this process, heating by the heating unit (400) is executed continuously. Accordingly, an umbrella (1) is dried within a short time as the hot wind is self-circulated to reheat the umbrella (1). The time for drying ...

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Номер записи: 2
28-11-2018 дата публикации

POTABLE SHOE DEODORIZATION DEVICE USING PHOTOCATALYST

Номер: KR1020180126990A
Автор: KIM, SO HEE, PARK, JOO WAN, LEE, KWANG HEE, LEE, SUN AH
Принадлежит:

A portable shoe deodorization device using photocatalyst of the present invention comprises: an insertion unit inserted into an inner space of a shoe and having a plurality of through-holes; a length adjustment unit connected to the insertion unit and capable of adjusting a length; a photocatalyst unit provided on an inner surface or an outer surface of the insertion unit; a light source unit provided inside the insertion unit and having at least one light emitting device for irradiating light toward the photocatalyst unit; and a power supply unit for supplying power for driving the light source unit. According to at least one of the embodiments of the present invention, bacteria and bad smell inside a shoe can be effectively removed by a photocatalytic effect. Also, by using photocatalyst, the portable shoe deodorization device can be used semi-permanently. In addition, according to at least one of the embodiments of the present invention, since a UV LED is used, power consumption is small ...

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Номер записи: 3
06-09-2017 дата публикации

COMPOSITION FOR PREVENTING OR TREATING NEURODEGENERATIVE DISEASE COMPRISING RED GINSENG OIL AS ACTIVE INGREDIENT

Номер: KR101775267B1
Автор: JUN, MI RA, LEE, SEON AH, YOUN, KUM JU, PARK, JI HYUN
Принадлежит: DONG-A UNIVERSITY RESEARCH FOUNDATION FOR INDUSTRY-ACADEMY COOPERATION

The present invention relates to a pharmaceutical composition for preventing or treating neurodegenerative diseases comprising red ginseng oil as an active ingredient. The red ginseng oil of the present invention can be used for pharmaceutical medicines, functional foods, etc. for preventing or treating (alleviating) neurodegenerative diseases including Alzheimer′s diseases by having excellent activities of inhibiting Aβ-inducing neurotoxicity. The red ginseng oil, as a material originated from natural materials, has excellent stability without cytotoxicity so a composition comprising the red ginseng oil as an active ingredient can be safely used for a long period of time without side effects to human bodies. COPYRIGHT KIPO 2017 ...

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Номер записи: 4
07-08-2017 дата публикации

COMPOSITION FOR PREVENTING OR TREATING DEGENERATIVE NEURONAL DISEASE COMPRISING NOBILETIN AS ACTIVE INGREDIENT

Номер: KR1020170090073A
Автор: JUN, MI RA, LEE, SEON AH, YOUN, KUM JU, PARK, JI HYUN
Принадлежит:

The present invention relates to a pharmaceutical composition for prevention or treatment of degenerative neuronal disease comprising nobiletin as an active ingredient. The nobiletin of the present invention has excellent activity to inhibit Aβ-induced neurotoxicity, thereby being useful for pharmaceutical medicines and functional food for preventing or treating (alleviating) degenerative neuronal disease including Alzheimer′s. In particular, the nobiletin of the present invention is a substance derived from pearl grass which is a natural product, and has stability without cytotoxicity, and thus the composition of the present invention comprising the same as an active ingredient is safe even with a long-term use without adverse effects on a human body. COPYRIGHT KIPO 2017 ...

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Номер записи: 5
17-11-2017 дата публикации

SYSTEM AND METHOD FOR RECOMMENDING EXERCISE INTENSITY FOR EACH USER THROUGH PHYSIOLOGIC SIGNAL ANALYSIS AND LEARNING

Номер: KR1020170126237A
Автор: CHUNG, KI SOOK, KIM, TAE HYUN, LEE, SEON AH, KEUM, CHANG SUP, LEE, JEA JUN, JUNG, PIL SU
Принадлежит:

The present invention relates to a system and method for recommending exercise intensity for each user through physiologic signal analysis and learning. The system according to the present invention includes a user terminal which collects and analyzes the physiologic information of the user while the user take exercise, determines a physical anomaly state of the physiologic information collected from the user based on the boundary value of each step of the user stored in advance, and provides exercise intensity recommendation information to the user, and a server which configures a learning model for the corresponding user by analyzing the physiological information of the user, and provides the boundary value of each step calculated by applying the physiological information received from the user terminal to the learning model in a predetermined time unit, to the user terminal. Accordingly, the present invention can provide a convenient and stable exercise intensity recommendation service ...

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Номер записи: 6
10-07-2017 дата публикации

COMPOSITION FOR IMPROVING SKIN CONDITION CONTAINING PRAERUPTORIN A

Номер: KR1020170079977A
Автор: LEE, SUN AH, JIN, MU HYUN, LEE, SANG HWA
Принадлежит:

The present invention relates to a cosmetic composition exhibiting excellent effects on skin moisturization, elasticity enhancement, wrinkle amelioration, whitening, or anti-saccharification within skin. The present invention further relates to a pharmaceutical composition, and a health food. The cosmetic composition of the present invention shows outstanding effects on skin-whitening, skin elasticity enhancement, skin wrinkle amelioration, or skin moisturization. A compound represented by chemical formula 1 contained as an active ingredient of the cosmetic composition can be used as raw materials for cosmetic products, pharmaceutical components, or health foods showing excellent skin condition improvement effects while being safe on skin. COPYRIGHT KIPO 2017 ...

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Номер записи: 7
27-11-2017 дата публикации

COMPOSITION FOR PREVENTING OR TREATING DEGENERATIVE BRAIN DISEASE CONTAINING BIOCHANIN A AS ACTIVE INGREDIENT

Номер: KR101801478B1
Автор: JUN, MI RA, YOUN, KUM JU, LEE, SEON AH, PARK, JI HYUN
Принадлежит: DONG-A UNIVERSITY RESEARCH FOUNDATION FOR INDUSTRY-ACADEMY COOPERATION

The present invention relates to a pharmaceutical composition for preventing or treating degenerative brain disease, containing biochanin A or a pharmaceutically acceptable salt thereof as an active ingredient. More specifically, biochanin A inhibits activities of beta-secretase 1 (BACE1) and suppresses production of beta-amyloid plaque, thereby being useful for preventing or treating degenerative brain disease. COPYRIGHT KIPO 2017 ...

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Номер записи: 8
15-11-2016 дата публикации

중간체로서 광학 활성 3-아미노-1-프로판올 유도체의 제조방법 및 상기 중간체를 이용한 (S)-둘록세틴의 제조방법

Номер: KR0101675450B1
Автор: 이기인, 이선아, 황인택, 임석태, 허재현, 허정희
Принадлежит: 한국화학연구원, (주) 파마젠

... 본 발명에 따른 높은 광학 활성을 가지는 3-아미노-1-프로판올 유도체의 제조방법 및 이를 이용한 거울상 이성질체적으로 순수한 둘록세틴의 제조방법은 광학 활성을 가지는 3-아미노-1-프로판올 유도체를 종래의 어떤 방법보다도 더 높은 수율과 광학적 순도(ee)로 수득할 수 있으며, 이를 중간체로 이용함으로써 거울상 이성질체적으로 순수하며 높은 광학적 순도(ee)로 둘록세틴을 제조할 수 있다.

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Номер записи: 9
10-07-2017 дата публикации

COMPOSITION FOR IMPROVING SKIN CONDITIONS COMPRISING PSEUDOLARIC ACID A

Номер: KR1020170079981A
Автор: LEE, SUN AH, JIN, MU HYUN, LEE, SANG HWA
Принадлежит:

The present invention relates to a cosmetic composition, a pharmaceutical composition and a health food having excellent anti-saccharification, whitening, wrinkle alleviation, elasticity improvement, skin moisturizing or anti-inflammatory effects. The composition of the present invention has excellent effects on skin whitening, skin elasticity improvement, skin wrinkle alleviation, skin moisturizing or anti-inflammation. A compound represented by chemical formula 1, which is an active ingredient of the composition, can be used as a cosmetic material, a pharmaceutical component or a health food material being safe for skin and having excellent skin condition improvement effects. COPYRIGHT KIPO 2017 ...

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Номер записи: 10
15-02-2016 дата публикации

COMPOSITION FOR SKIN WHITENING COMPRISING KIRENOL OR SIGESBECKIA PUBESCENS L. EXTRACT

Номер: KR1020160015502A
Автор: HWANG, JAE KWAN, KIM, MI BO, LEE, SUN AH
Принадлежит:

The present invention relates to a new usage of kirenol, a Sigesbeckia pubescens L. extract, or a fraction thereof and, more specifically, to a composition for skin whitening containing kirenol or a Sigesbeckia pubescens L. extract containing the same. The extract can be extracted by one or more solvent selected from a group including water, a C1 to C6 organic solvent, subcritical fluid, and supercritical fluid. According to the present invention, the kirenol or a Sigesbeckia pubescens L. extract containing the same controls melanin generation and tyrosinase activity, thereby having an excellent skin whitening effect. Also, the skin whitening composition in the present invention is a natural material, thereby being safely used without side effects and being used as cosmetics or foods. COPYRIGHT KIPO 2016 (AA) Melanin contents in comparison with a control group (BB) Specimen (CC) Kirenol ...

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Номер записи: 11
29-12-2011 дата публикации

METHOD FOR PREPARING [1,2,3]-OXATHIAZOLIDINE-2,2-DIOXIDE OR [1,2,5]-THIADIAZOLIDINE-1,1-DIOXIDE DERIVATIVES

Номер: WO2011162514A3
Автор: LEE, Kee In, LEE, Hyeon Kyu, CHOI, Eun Bok, KWACK, Se Hoon, LEE, Sun Ah, LEE, Eun Sil, HAN, Jou Ae, KANG, So Yeong
Принадлежит:

The present invention provides a novel method for preparing [1,2,3]-oxathiazolidine-2,2-dioxide or [1,2,5]-thiadiazolidine-1,1-dioxide derivatives. According to the manufacturing method of the present invention, it is possible to conveniently and effectively prepare enantiomerically pure [1,2,3]-oxathiazolidine-2,2-dioxide or [1,2,5]-thiadiazolidine-1,1-dioxide derivatives by asymmetric reduction of 5H-[1,2,3]-oxathiazole-2,2-dioxide or [1,2,5]-thiadiazoline-1,1-dioxide in the presence of a rhodium compound catalyst and a hydrogen donor.

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Номер записи: 12
15-11-2016 дата публикации

광학 활성 3-클로로-1-아릴프로판-1-올 유도체로부터 3-아미노-1-아릴프로판-1-올 유도체의 제조방법

Номер: KR0101675440B1
Автор: 이기인, 이선아, 황인택, 허정희, 임석태, 허재현
Принадлежит: 한국화학연구원, (주) 파마젠

... 본 발명은 요오드화합물 존재 하에 광학 활성 3-클로로-1-아릴프로판-1-올 화합물을 아민 유도체와 반응시키는 단계를 포함하는, 광학 활성 3-아미노-1-아릴프로판-1-올 유도체의 제조방법에 관한 것이다. 본 발명의 제조방법은 단일 단계의 반응으로 광학 활성 3-클로로-1-아릴프로판-1-올 유도체를 직접 아민화하여 3-아미노-1-아릴프로판-1-올 유도체로 전환하므로 반응물의 광학 순도를 유지하면서 간단한 공정을 통해 높은 수율로 다양한 광학 활성 분자의 핵심 중간체가 되는 화합물을 제공할 수 있다. 따라서, 상기 제조방법을 높은 광학 순도로 본 발명의 제조방법에서 반응물로 사용되는 광학 활성 3-클로로-1-아릴프로판-1-올 유도체를 제조하는 방법 및 추가적인 치환반응과 조합함으로써 높은 광학 순도로 (S)-둘록세틴, (R)-플록세틴, (R)-토목세틴 또는 (R)-니속세틴 등의 약물을 제조하는 데 유용하게 사용될 수 있다.

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Номер записи: 13
12-10-2017 дата публикации

NOVEL COMPOUND ISOLATED FROM TENEBRIO MOLITOR AND METHOD FOR ISOLATING SAME

Номер: WO2017175915A1
Автор: YUN, Eun-Young, HWANG, Jae-Sam, KIM, Mi-Ae, BAEK, Min-Hee, JUN, Mi-Ra, YOUN, Kum-Ju, LEE, Seon-Ah
Принадлежит:

The present invention relates to a novel compound isolated from Tenebrio molitor and a method for isolating the same. The novel compound is expected to have a better effect in treating Alzheimer's since the novel compound is isolated from an ethyl acetate fraction showing an anti-Alzheimer's effect. Therefore, the novel compound can be easily used as a pharmaceutical composition for treating or preventing brain diseases of the elderly or as a health functional food.

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Номер записи: 14
25-04-2016 дата публикации

METHOD FOR PREPARING 3-AMINO-ARYLPROPAN-1-OL DERIVATIVE FROM OPTICALLY ACTIVE 3-CHLORO-1-ARYLPROPAN-1-OL DERIVATIVE

Номер: KR1020160044117A
Автор: LEE, KEE IN, LEE, SUN AH, HWANG, IN TAEK, HEOR, JUNG HEE, LIM, SUK TAE, HEO, JAE HYEON
Принадлежит:

The present invention relates to a method for preparing an optically active 3-amino-1-arylpropan-1-ol derivative, including the step of making an optically active 3-chloro-1-arylpropan-1-ol compound react with an amine derivative. The method according to the present invention allows direct amination of an optically active 3-chloro-1-arylpropan-1-ol derivative through a single-step reaction. Thus, it is possible to provide a compound functioning as a key intermediate of various optically active molecules through a simple process with high yield, while maintaining the optical purity of the reactant. Therefore, the method may be used for preparing medicines, such as (S)-Duloxetin, (R)-Fluoxetine, (R)- Tomoxetine or (R)- Nisoxetine, with high optical purity by combining the method for preparing an optically active 3-chloro-1-arylpropan-1-ol derivative as a reactant of the method with an additional substitution reaction. COPYRIGHT KIPO 2016 (AA) Tomoxetine (BB) Fluoxetine (CC) 3-amino-1-propanol ...

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Номер записи: 15
28-02-2018 дата публикации

METHOD FOR MAXIMIZING LEVEL OF ANTHOCYANIN AND POLYPHENOL IN ARONIA FREEZE-DRIED POWER

Номер: KR1020180020925A
Автор: LEE, MIN HO, LEE, SUN A, LUKASZ MARACH
Принадлежит:

The present invention relates to a method for maximizing a level of anthocyanin and polyphenol in an aronia freeze-dried power. A pressure in a freeze-drying process is 30 to 60 Pa, a primary freeze-drying temperature is -30 to -40°C and a secondary freeze-drying temperature is 25 to 30°C. COPYRIGHT KIPO 2018 ...

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Номер записи: 16
25-09-2014 дата публикации

SIGNAL TRANSMITTING APPARATUS, SIGNAL TRANSMITTING METHOD, AND SYSTEM FOR TRANSMITTING AND RECEIVING SIGNAL

Номер: WO2014148813A1
Автор: KANG, Donghyun, LEE, Seonah, OH, Sejin, CHOI, Jongsung, KWON, Younghwan, AN, Seungjoo, PARK, Jungwook, KIM, Jinpil, YANG, Seungryul, MOON, Kyoungsoo
Принадлежит:

Disclosed are a signal transmitting method, a signal transmitting apparatus, and a system for transmitting and receiving a signal. The signal transmitting method comprises the steps of: discovering a companion device using a multicast mode; receiving and storing device type information from the discovered companion device; receiving an application uniform resource identifier (URI) and storing the application URI to correspond to the device type information; and identifying the device type information of the companion device selected by a user and transmitting to the selected companion device the application URI corresponding to the device type information.

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Номер записи: 17
10-07-2017 дата публикации

COMPOSITION FOR IMPROVING SKIN CONDITION CONTAINING AJUGOL

Номер: KR1020170079975A
Автор: LEE, SUN AH, JIN, MU HYUN, LEE, SANG HWA
Принадлежит:

The present invention relates to a cosmetic composition exhibiting excellent effects on skin moisturization, elasticity enhancement, wrinkle amelioration, whitening, or anti-saccharification within skin. The present invention further relates to a pharmaceutical composition, and a health food. The cosmetic composition of the present invention shows outstanding effects on skin-whitening, skin elasticity enhancement, skin wrinkle amelioration, or skin moisturization. A compound represented by chemical formula 1 contained as an active ingredient of the cosmetic composition can be used as raw materials for cosmetic products, pharmaceutical components, or health foods showing excellent skin condition improvement effects while being safe on skin. COPYRIGHT KIPO 2017 ...

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Номер записи: 18
08-10-2015 дата публикации

COMPOSITION FOR SKIN WHITENING CONTAINING ALLIUM HOOKERI EXTRACT AS ACTIVE INGREDIENT

Номер: KR1020150113709A
Автор: HWANG, JAE KWAN, LEE, SUN AH, RHIM, DONG BIN
Принадлежит:

The present invention relates to a novel use of an Allium hookeri extract and, more specifically, to a composition for skin whitening containing an Allium hookeri extract. The Allium hookeri extract exhibits excellent whitening effects by inhibiting an activity of tyrosinase and production of melanin, thereby being applied for an active ingredient in a cosmetic composition for skin whitening, a food composition, or a pharmaceutical composition. COPYRIGHT KIPO 2016 (AA) Melanin contents in comparison with a control group(%) (BB) Specimen (CC) Allium hookeri extract (µg/ml) ...

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Номер записи: 19
10-07-2017 дата публикации

COMPOSITION FOR IMPROVING SKIN CONDITION CONTAINING RUBUSOSIDE

Номер: KR1020170079974A
Автор: LEE, SUN AH, JIN, MU HYUN, LEE, SANG HWA
Принадлежит:

The present invention relates to a cosmetic composition exhibiting excellent effects on skin moisturization, elasticity enhancement, wrinkle amelioration, whitening, or anti-saccharification within skin. The present invention further relates to a pharmaceutical composition, and a health food. The cosmetic composition of the present invention shows outstanding effects on skin-whitening, skin elasticity enhancement, skin wrinkle amelioration, or skin moisturization. A compound represented by chemical formula 1 contained as an active ingredient of the cosmetic composition can be used as raw materials for cosmetic products, pharmaceutical components, or health foods showing excellent skin condition improvement effects while being safe on skin. COPYRIGHT KIPO 2017 ...

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Номер записи: 20
24-02-2017 дата публикации

POSITION MEASUREMENT METHOD BASED ON WEIGHTED TRIANGULATION AND INDOOR POSITIONING METHOD USING SAME

Номер: KR101709411B1
Автор: PARK, SANG SOO, CHOI, HA YEON, KOO, YOUNG KYOUNG, LEE, SEON A
Принадлежит: EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION

A weighted triangulation according to an embodiment of the present invention may include the steps of: measuring each of reference signal strength indications (RSSI) of wireless signals respectively received from at least three stationary base stations; estimating each of estimated distances from user terminal to each of the stationary base stations on the basis of the measured RSSI values; determining each of weighted values with respect to each of vertexes of an overlapping area when the overlapping area is deducted by overlapping virtual circles each of which has a center at each of installation positions of the stationary base stations and a radius of each of the estimated distances; and calculating a weighted center of gravity of a polygon formed by the vertexes of the overlapping area using the weighted values to determine the weighted center of gravity as a position of the terminal. COPYRIGHT KIPO 2017 (AA) Start (BB) End (S11) Measure RSSI of wireless signals (S12) Estimate estimation ...

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Номер записи: 21
29-12-2011 дата публикации

METHOD FOR PREPARING [1,2,3]-OXATHIAZOLIDINE-2,2-DIOXIDE OR [1,2,5]-THIADIAZOLIDINE-1,1-DIOXIDE DERIVATIVES

Номер: WO2011162514A2
Автор: LEE, Kee In, LEE, Hyeon Kyu, CHOI, Eun Bok, KWACK, Se Hoon, LEE, Sun Ah, LEE, Eun Sil, HAN, Jou Ae, KANG, So Yeong
Принадлежит:

The present invention provides a novel method for preparing [1,2,3]-oxathiazolidine-2,2-dioxide or [1,2,5]-thiadiazolidine-1,1-dioxide derivatives. According to the manufacturing method of the present invention, it is possible to conveniently and effectively prepare enantiomerically pure [1,2,3]-oxathiazolidine-2,2-dioxide or [1,2,5]-thiadiazolidine-1,1-dioxide derivatives by asymmetric reduction of 5H-[1,2,3]-oxathiazole-2,2-dioxide or [1,2,5]-thiadiazoline-1,1-dioxide in the presence of a rhodium compound catalyst and a hydrogen donor.

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Номер записи: 22
27-11-2017 дата публикации

COMPOSITION FOR PREVENTING OR TREATING DEGENERATIVE BRAIN DISEASES COMPRISING FLAVANONE DERIVATIVE AS ACTIVE INGREDIENT

Номер: KR101801479B1
Автор: JUN, MI RA, YOU, YOON JIN, YOUN, KUM JU, LEE, SEON AH, PARK, JI HYUN
Принадлежит: DONG-A UNIVERSITY RESEARCH FOUNDATION FOR INDUSTRY-ACADEMY COOPERATION

The present invention relates to a pharmaceutical composition for preventing or treating degenerative brain diseases comprising a flavanone derivative as an active ingredient. Specifically, the pharmaceutical composition can be useful for preventing or treating degenerative brain diseases by inhibiting the activity of beta-secretase 1 (BACE1) to inhibit the production of beta-amyloid plaques. COPYRIGHT KIPO 2017 (AA) Hesperetin (BB) Naringenin (CC) Hesperidin ...

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Номер записи: 23
04-07-2017 дата публикации

COMPOSITION FOR PREVENTING OR TREATING NEURODEGENERATIVE DISEASES COMPRISING CORILAGIN

Номер: KR1020170076264A
Автор: JUN, MI RA, YOUN, KUM JU, LEE, SEON AH, PARK, JI HYUN
Принадлежит:

The present invention relates to a pharmaceutical composition for preventing or treating neurodegenerative diseases comprising corilagin as an effective component. Loganin of the present invention has excellent activity in inhibiting Aβ-derived neurotoxicity, so as to be useful for pharmaceutical medicines and functional foods for preventing or treating (alleviating) neurodegenerative diseases including Alzheimer′s. In particular, since the corilagin of the present invention is a material derived from a natural substance, Phyllanthus urinaria L. and has stability without cytotoxicity, the composition of the present invention containing the corilagin as an effective component has an advantage of being safe over a long-term use without an adverse effect on the human body. COPYRIGHT KIPO 2017 ...

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Номер записи: 24
28-02-2018 дата публикации

COMPOSITION FOR PREVENTING OR TREATING DEGENERATIVE BRAIN DISEASES CONTAINING ISOFLAVONE AS ACTIVE INGREDIENT

Номер: KR1020180020718A
Автор: JUN, MI RA, PARK, JI HYUN, YOUN, KUM JU, LEE, SEON AH
Принадлежит:

The present invention relates to a pharmaceutical composition for preventing or treating degenerative brain disease containing isoflavone as an active ingredient. More specifically, isoflavone can be useful for preventing or treating degenerative brain disease through suppression of beta-amyloid plaque production by inhibiting activities of beta-secretase 1 (BACE1). COPYRIGHT KIPO 2018 ...

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Номер записи: 25
16-12-2015 дата публикации

신호 송신 장치, 신호 송신 방법 및 신호 송수신 시스템

Номер: KR1020150140631A
Автор: 강동현, 이선아, 오세진, 최종성, 권영환, 안승주, 박정욱, 김진필, 양승률, 문경수
Принадлежит:

... 신호 송신 방법, 신호 송신 장치 및 신호 송수신 시스템이 개시된다. 신호 송신 방법은 멀티캐스트 방식을 이용하여 컴패니언 장치(companion device)를 검색(discovery)하는 단계, 검색된 컴패니언 장치로부터 장치 타입 정보를 수신하여 저장하는 단계, 어플리케이션 URI(Uniform Resource Identifier)를 수신하고 장치 타입 정보에 대응시켜 저장하는 단계 및 사용자에 의해 선택된 컴패니언 장치의 장치 타입 정보를 확인하고, 장치 타입 정보에 대응되는 어플리케이션 URI를 선택된 컴패니언 장치로 전송하는 단계를 포함한다.

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Номер записи: 26
11-08-2016 дата публикации

중간체로서 광학 활성 3-아미노-1-페닐프로판올 유도체의 제조방법 및 상기 중간체를 이용한 광학 활성 약학적 산물의 제조방법

Номер: KR0101644016B1
Автор: 이기인, 이선아, 황인택, 임석태, 허재현, 허정희, 이도민
Принадлежит: 한국화학연구원, (주) 파마젠

... 본 발명은 스피로보레이트 에스테르(spiroborate ester) 촉매 및 수소공여체의 존재 하에 비대칭 환원반응시키는 단계를 포함하는, 80% 이상의 거울상 이성질체 잉여율(enanthiomeric excess; ee)로 (R) 또는 (S)의 광학 활성을 갖는 3-아미노-1-페닐프로판올 유도체를 제조하는 방법; 및 상기 촉매를 이용하여 중간체인 (R)- 또는 (S)-3-아미노-1-페닐프로판올 유도체를 생산하는 단계를 포함하는, 광학 활성 약학적 산물을 제조하는 방법에 관한 것이다.

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Номер записи: 27
20-08-2018 дата публикации

PHAMACEUTICAL COMPOSITION FOR TREATING DEGENERATIVE BRAIN DISEASE CONTAINING COMPOUND ISOLATED FROM TENEBRIO MOLITOR

Номер: KR101890062B1
Автор: JUN, MI RA, YOUN, KUM JU, LEE, SEON AH, LEE, SEUNG EUN, YUN, EUN YOUNG
Принадлежит: DONG-A UNIVERSITY RESEARCH FOUNDATION FOR INDUSTRY-ACADEMY COOPERATION, INDUSTRY ACADEMY COOPERATION FOUNDATION OF SEJONG UNIVERSITY

The present invention relates to a phamaceutical composition for treating degenerative brain disease containing a compound isolated from Tenebrio molitor, wherein the compound TM-1 according to the present invention exists in the Tenebrio molitor, protects nerve cells against Aβ-induced toxicity while there is little cytotoxicity. In addition to inhibiting oxidative stress, the composition has an anti-inflammatory effect which blocks the expression of inflammatory biomarkers through the phosphorylation inhibition of NF-κB, which is an inflammatory regulatory transcription factor, and JNK and p38 MAPKs, which are at higher levels, so that the compound TM-1 may be useful for prevention or treatment of the degenerative brain disease, particularly, Alzheimer′s dementia. COPYRIGHT KIPO 2018 ...

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Номер записи: 28
12-08-2015 дата публикации

MOBILE TERMINAL AND METHOD FOR CONTROLLING SAME

Номер: KR1020150091607A
Автор: LEE, SUN AH, BAEK, SONG YI, YANG, YOON SEOK, JUNG, SE HYUN, MOON, KYUNG JIN
Принадлежит:

The present invention relates to a mobile terminal and, more specifically, to a mobile terminal which can provide various functions by using a cover including an opening and to a controlling method thereof. The mobile terminal relating to an embodiment of the present invention comprises a cover including an opening; a touch screen; a sensing part detecting opening of the cover; and a control part receiving a memo through a pointer on an exposed area of the touch screen exposed through the opening, when a memo mode is executed when the cover is detected to be closed through the sensing part, and controlling so that the memo inputted on the touch screen is displayed, when the cover is detected to be opened through the sensing part. COPYRIGHT KIPO 2015 (AA) Start (BB) No (CC) Yes (DD) End (S410) Execute a memo mode with a cover closed (S420) Input a memo to an exposed area of the touch screen (S430) Detect the opening of the cover? (S440) Display the inputted memo at a location corresponding ...

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Номер записи: 29
10-04-2017 дата публикации

NOVEL COMPOUND ISOLATED FROM MEAL BEETLE AND ISOLATION METHOD THEREOF

Номер: KR101725070B1
Автор: YUN, EUN YOUNG, HWANG, JAE SAM, KIM, MI AE, BAEK, MIN HEE, JUN, MI RA, YOUN, KUM JU, LEE, SEON AH
Принадлежит: REPUBLIC OF KOREA(MANAGEMENT : RURAL DEVELOPMENT ADMINISTRATION), DONG-A UNIVERSITY RESEARCH FOUNDATION FOR INDUSTRY-ACADEMY COOPERATION

The present invention relates to a novel compound isolated from meal beetle, and to an isolation method thereof. The novel compound is isolated from a fraction of ethyl acetate showing anti-Alzheimer′s effects, and thus is anticipated to have outstanding therapeutic effects on Alzheimer′s disease, thereby being useful as functional health foods or pharmaceutical compositions for preventing or treating senescence-related cerebropathia. COPYRIGHT KIPO 2017 ...

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Номер записи: 30
19-10-2015 дата публикации

METHOD FOR PREPARING 3-AMINO-1-PHENYLPROPANOL DERIVATIVE AS INTERMEDIATE AND OPTICALLY ACTIVE PHARMACEUTICAL PRODUCT BY USING INTERMEDIATE

Номер: KR1020150116956A
Автор: LEE, KEE IN, LEE, SUN AH, HWANG, IN TAEK, LIM, SUK TAE, HEO, JAE HYEON, HEOR, JUNG HEE, LEE, DO MIN
Принадлежит:

The present invention relates to a method for preparing a 3-amino-1-phenylpropanol derivative having (R) or (S) optical activity with 80% or more of an enantiomeric excess (ee), which includes a step of performing an asymmetric reduction reaction in the presence of a spiroborate ester catalyst and a hydrogen donor. The invention also relates to a method for preparing an optically active pharmaceutical product, which includes a step of preparing a (R)- or (S)-3-amino-1-phenylpropanol derivative, that is an intermediate, by using the catalyst. COPYRIGHT KIPO 2016 (AA) 3-amino-1-phenylpropanol (BB) Tomoxetine (CC) Nisoxetine (DD) Fluoxetine ...

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Номер записи: 31