Настройки

Укажите год
-

Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

Подробнее
-

Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

Подробнее

Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
Ведите корректный номера.
Ведите корректный номера.
Ведите корректный номера.
Ведите корректный номера.
Укажите год
Укажите год
Применить Всего найдено 24. Отображено 24.
03-08-2016 дата публикации

락토바실러스 파라카제이(Lactobacillus paracasei)를 유효성분으로 포함하는 Ｔｈ1-매개 면역 질환 또는 Ｔｈ2-매개 면역 질환의 예방, 개선 또는 치료용 조성물

Номер: KR0101644595B1
Автор: 이소영, 손동화, 신희순, 박소림, 도정룡, 정성근, 정민유, 엄지은, 임신혁
Принадлежит: 한국식품연구원

... 본 발명은 락토바실러스 파라카제이(Lactobacillus paracasei)를 유효성분으로 포함하는 Th1-매개 면역 질환 또는 Th2-매개 면역 질환의 예방, 개선 또는 치료용 조성물에 관한 것이다. 본 발명의 락토바실러스 파라카제이는 조절 T 세포를 활성화시키고, 항염증 사이토카인인 IL-10 생성을 증가시키며, 면역활성 사이토카인인 IL-12 생성을 억제시킴으로써 Th1-매개 면역 질환 또는 Th2-매개 면역 질환을 효과적으로 제어하는바 항알레르기성 조성물 및 항염증성 조성물로 사용이 가능한 이점이 있다.

Подробнее
Номер записи: 1
29-10-2015 дата публикации

METHOD FOR PREPARING PHYSIOLOGICAL-FUNCTIONAL EXTRACT DERIVED FROM SARCODON ASPRATUS

Номер: KR1020150121331A
Автор: KIM, HYUN KU, DO, JEONG RYONG, CHUNG, MIN YU
Принадлежит:

Provided are a method for preparing an enhanced physiological-functional material or a Sarcodon aspratus extract having an enhanced physiological activity, and a Sarcodon aspratus extract prepared thereby. The present invention can be highly used as base data to increase an industrial utility value of Sarcodon aspratus and develop high value-added products of Sarcodon aspratus. The method for preparing an enhanced physiological-functional material or a Sarcodon aspratus extract having an enhanced physiological activity comprises the following steps: (a) treating Sarcodon aspratus powder with 95% ethanol; (b) treating a Sarcodon aspratus extract treated with 95% ethanol, which is a product of step (a), with a solvent selected from a group consisting of hexane, chloroform, ethyl acetate, butanol and water; and (c) obtaining a Sarcodon aspratus extract as a product of step (b). COPYRIGHT KIPO 2016 ...

Подробнее
Номер записи: 2
07-01-2016 дата публикации

COMPOSITION COMPRISING MOLLUGO PENTAPHYLLA L. EXTRACT, ALISMA PLANTAGO-AQUATICA L. VAR. ORIENTALE SAMUELSSON EXTRACT, ELAEOCARPUS SYLVESTRIS VAR. ELLIPTICUS (THUNB.) HARA EXTRACT, OR CIMICIFUGA ACERINA (S. ET Z.) TANAKA EXTRACT FOR PREVENTING, ALLEVIATING, OR TREATING Th2-MEDIATED IMMUNE DISEASES

Номер: KR1020160001805A
Автор: SHON, DONG HWA, SHIN, HEE SOON, CHAI, OK HEE, BAE, MIN JUNG, CHOI, DAE WOON, JUNG, SUN YOUNG, SEE, HYE JEONG, LEE, SO YOUNG, DO, JEONG RYONG, JUNG, SUNG KEUN, CHUNG, MIN YU
Принадлежит:

The present invention relates to a composition comprising at least one extract selected from the group consisting of a Mollugo pentaphylla L. extract, an Alisma plantago-aquatica L. var. orientale Samuelsson extract, an Elaeocarpus sylvestris var. ellipticus (Thunb.) Hara extract, and a Cimicifuga acerina (S. et Z.) TANAKA extract as an active ingredient, for preventing, alleviating, or treating Th2-mediated immune diseases. According to the present invention, the extract is capable of preventing, alleviating, or treating Th2-mediated immune diseases by having IL-4 generation inhibitory activities and degranulation inhibitory activities of mast cells. COPYRIGHT KIPO 2016 (AA) Food + BUFFER (BB) Food + C48/80 (CC) Mollugo pentaphylla L. mg/ml ...

Подробнее
Номер записи: 3
27-10-2017 дата публикации

COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING INFLAMMATORY DISEASES OR ALLERGIC DISEASES COMPRISING EXTRACT OF DAVALLIA MARIESII

Номер: KR1020170119658A
Автор: SHON DONG HWA, SHIN HEE SOON, CHAI OK HEE, BAE MIN JUNG, CHOI DAE WOON, JUNG SUN YOUNG, SEE HYE JEONG, LEE SO YOUNG, DO JEONG RYONG, JUNG SUNG KEUN, CHUNG MIN YU
Принадлежит:

The present invention relates to a composition for preventing, alleviating, or treating Th1-mediated immune disease or Th2-mediated immune disease, comprising, as an active ingredient, one or more extracts selected from the group consisting of a Davallia mariesii extract, an Empetrum nigrum var. japonicum extract, a Narcissus tazetta var. chinensis extract, a Marsilea quadrifolia extract, a Nerium indicum extract, a Potentilla discolor extract, and a Gleichenia japonica extract. According to the present invention, the extract may prevent, alleviate, or treat Th1-mediated immune disease or Th2-mediated immune disease by inhibiting the formation of IL-4; inhibiting the permeation of allergens into intestinal epithelial cells; inhibiting the degranulation of mast cells; and inducing the differentiation into Treg cells. COPYRIGHT KIPO 2017 ...

Подробнее
Номер записи: 4
14-08-2017 дата публикации

COMPOSITION FOR TREATING, PREVENTING, OR AMELIORATING FATTY LIVER DISEASES CONTAINING LAVER (PORPHYRA TENERA) EXTRACT

Номер: KR1020170092975A
Автор: CHOI, HYO KYOUNG, HWANG, JIN TAEK, PARK, JAE HO, HUR, HAENG JEON, SUNG, MI JEONG, CHUNG, MIN YU, LEE, AE SIN, YOON, YEO CHO, SHIN, EUN JU
Принадлежит:

The present invention relates to a composition for treating, preventing, or ameliorating fatty liver diseases. By containing a laver (Porphyra tenera) extract as an active ingredient, it is possible to treat, prevent, or ameliorate non-alcoholic fatty liver diseases. In addition, the composition can be taken as foods since the composition is not toxic. COPYRIGHT KIPO 2017 (AA) OA + example 1 (BB) OA + example 2 (CC) OA + example 3 (DD) OA + example 4 (EE) OA + example 5 ...

Подробнее
Номер записи: 5
18-07-2018 дата публикации

넉줄고사리 추출물을 포함하는 염증 질환 또는 알레르기 질환의 예방, 개선 또는 치료용 조성물

Номер: KR0101879826B1
Автор: 손동화, 신희순, 채옥희, 배민정, 최대운, 정선영, 시혜정, 이소영, 도정룡, 정성근, 정민유
Принадлежит: 한국식품연구원

... 본 발명은 넉줄고사리(Davallia mariesii) 추출물, 시로미(Empetrum nigrum var. japonicum) 추출물, 수선화(Narcissus tazetta var. chinensis) 추출물, 네가래(Marsilea quadrifolia) 추출물, 협죽도(Nerium indicum) 추출물, 솜양지꽃(Pontentilla discolor) 추출물 및 풀고사리(Gleichenia japonica) 추출물로 구성된 군으로부터 선택되는 하나 이상의 추출물을 유효성분으로 포함하는 Th1-매개 면역 질환 또는 Th2-매개 면역 질환의 예방, 개선 또는 치료용 조성물에 관한 것이다. 본 발명에 따르면, 상기 추출물은 IL-4 생성 억제, 알레르겐의 장상피세포 통과 억제, 비만세포의 탈과립 억제 및 Treg 세포로의 분화 유도 활성을 가짐으로 Th1-매개 면역 질환 또는 Th2-매개 면역 질환을 예방, 개선 또는 치료할 수 있다.

Подробнее
Номер записи: 6
21-01-2016 дата публикации

COMPOSITION COMPRISING LACTOBACILLUS CASEI AS ACTIVE INGREDIENT FOR PREVENTING, ALLEVIATING OR TREATING Th1-MEDIATED IMMUNE DISEASES OR Th2-MEDIATED IMMUNE DISEASES

Номер: KR1020160008059A
Автор: LEE, SO YOUNG, SHON, DONG HWA, SHIN, HEE SOON, LIM, SEONG IL, DO, JEONG RYONG, JUNG, SUNG KEUN, CHUNG, MIN YU, EOM, JI EUN, IM, SIN HYEOG
Принадлежит:

The present invention relates to a composition comprising Lactobacillus casei as an active ingredient for preventing, alleviating, or treating Th1-mediated immune diseases or Th2-mediated immune diseases. Lactobacillus casei of the present invention is capable of effectively controlling Th1-mediated immune diseases or Th2-mediated immune diseases, by activing control T cells, increasing generation of IL-10 which is anti-inflammatory cytokine, inhibiting generation IL-12 which is immune-activating cytokine, and reducing an amount of IgE antibodies produced. Therefore, the composition can be used as an anti-allergic composition and an anti-inflammatory composition. COPYRIGHT KIPO 2016 ...

Подробнее
Номер записи: 7
20-02-2017 дата публикации

개승마 추출물을 포함하는 알레르기 질환의 예방, 개선 또는 치료용 조성물

Номер: KR0101707673B1
Автор: 손동화, 신희순, 채옥희, 배민정, 최대운, 정선영, 시혜정, 이소영, 도정룡, 정성근, 정민유
Принадлежит: 한국식품연구원

... 본 발명은 석류풀(Mollugo pentaphylla) 추출물, 질경이택사(Alisma plantago-aquatica) 추출물, 담팥수(Eaeocarpus sylvestris) 추출물 및 개승마(Cimicifuga acerina) 추출물로 구성된 군으로부터 선택되는 하나 이상의 추출물을 유효성분으로 포함하는 Th2-매개 면역 질환의 예방, 개선 또는 치료용 조성물에 관한 것이다. 본 발명에 따르면, 상기 추출물은 IL-4 생성 억제 및 비만세포의 탈과립 억제 활성을 가짐으로 Th2-매개 면역 질환을 예방, 개선 또는 치료할 수 있다.

Подробнее
Номер записи: 8
02-04-2018 дата публикации

COMPOSITION FOR ALLEVIATING, PREVENTING, OR TREATING FATTY LIVER DISEASES CONTAINING SPRING ONION EXTRACT

Номер: KR1020180032765A
Автор: CHOI, HYO KYOUNG, HWANG, JIN TAEK, PARK, JAE HO, CHUNG, MIN YU, SUNG, MI JEONG, KIM, MUUNG SUNNY, SHIN, EUN JU
Принадлежит:

The present invention relates to a composition for alleviating, preventing, or treating fatty liver diseases, which contains a spring onion extract as an effective component so that non-alcohol dependent fatty liver diseases can be alleviated, prevented or treated. In addition, since the composition is not toxic, the composition can be ingested in a form of food. COPYRIGHT KIPO 2018 (AA) Control group (BB) OA + example 1 (CC) OA + example 2 (DD) OA + example 3 (EE) OA + example 4 (FF) OA + example 5 (GG) OA + example 6 (HH) OA + comparative example 1 ...

Подробнее
Номер записи: 9
07-01-2016 дата публикации

COMPOSITION FOR PREVENTING, MITIGATING OR TREATING Th2-MEDIATED IMMUNE DISEASES COMPRISING RANUNCULUS JAPONICUS THUNB. EXTRACT, ILLICIUM RELIGIOSUM SIEBOLD & ZUCC. EXTRACT, CHLORANTHUS JAPONICUS SIEB. EXTRACT, OR EUCOMMIA ULMOIDES OLIV. EXTRACT

Номер: KR1020160001806A
Автор: SHON, DONG HWA, SHIN, HEE SOON, CHAI, OK HEE, BAE, MIN JUNG, CHOI, DAE WOON, JUNG, SUN YOUNG, SEE, HYE JEONG, LEE, SO YOUNG, DO, JEONG RYONG, JUNG, SUNG KEUN, CHUNG, MIN YU
Принадлежит:

The present invention relates to a composition for preventing, mitigating, or treating Th2-mediated immune diseases, comprising one or more extracts selected from the group consisting of a Ranunculus japonicus Thunb. extract, an Illicium religiosum Siebold & Zucc. extract, a Chloranthus japonicus Sieb. extract, and an Eucommia ulmoides OLIV. extract. According to the present invention, the extracts have activities of inhibiting IL-4 generation and inhibiting mast cell degranulation, thereby preventing, mitigating, or treating Th2-mediated immune diseases. COPYRIGHT KIPO 2016 (AA) Ranunculus japonicus Thunb. mg/ml ...

Подробнее
Номер записи: 10
22-03-2016 дата публикации

COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING ALLERGIC DISEASES COMPRISING CHLORANTHUS JAPONICUS EXTRACT

Номер: KR1020160031480A
Автор: SHON, DONG HWA, SHIN, HEE SOON, CHAI, OK HEE, BAE, MIN JUNG, CHOI, DAE WOON, JUNG, SUN YOUNG, SEE, HYE JEONG, LEE, SO YOUNG, DO, JEONG RYONG, JUNG, SUNG KEUN, CHUNG, MIN YU
Принадлежит:

The present invention relates to a composition for preventing, alleviating, or treating Th2-mediated immunological diseases, comprising any one or more selected from the group consisting of a Ranunculus japonicus extract, an Illicium religiosum extract, a Chloranthus japonicus extract, and an Eucommia ulmoides extract, as an active ingredient. According to the present invention, the extracts have effects of preventing, alleviating, or treating Th2-mediated immunological diseases by having suppression activities of IL-4 generation and mast cell degranulation. COPYRIGHT KIPO 2016 (AA) Ranunculus japonicus mg/ml ...

Подробнее
Номер записи: 11
22-03-2016 дата публикации

COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING ALLERGY DISEASES, COMPRISING PODOCARPUS MACROPHYLLUS EXTRACT, DISTYLIUM RACEMOSUM EXTRACT, OR RHODODENDRON MUCRONULATUM EXTRACT

Номер: KR1020160031479A
Автор: SHON, DONG HWA, SHIN, HEE SOON, CHAI, OK HEE, BAE, MIN JUNG, CHOI, DAE WOON, JUNG, SUN YOUNG, SEE, HYE JEONG, LEE, SO YOUNG, DO, JEONG RYONG, JUNG, SUNG KEUN, CHUNG, MIN YU
Принадлежит:

The present invention relates to a composition for preventing, alleviating, or treating Th2-mediated immunological diseases, comprising one or more selected from the group consisting of a Rhamnus davurica extract, a Chrysosplenium grayanum extract, a Podocarpus macrophyllus extract, a Distylium racemosum extract, and a Rhododendron mucronulatum extract, as an active ingredient. According to the present invention, the extracts have effects of preventing, alleviating, or treating Th2-mediated immunological diseases by having suppression activities of IL-4 generation, the permeation of allergens through an intestinal epithelial cell, and mast cell degranulation. COPYRIGHT KIPO 2016 ...

Подробнее
Номер записи: 12
23-08-2016 дата публикации

괭이눈 추출물을 포함하는 알레르기 질환의 예방, 개선 또는 치료용 조성물

Номер: KR0101649707B1
Автор: 손동화, 신희순, 채옥희, 배민정, 최대운, 정선영, 시혜정, 이소영, 도정룡, 정성근, 정민유
Принадлежит: 한국식품연구원

... 본 발명은 갈매나무(Rhamnus davurica) 추출물, 괭이눈(Chrysosplenium grayanum) 추출물, 나한송(Podocarpus macrophyllus) 추출물, 조록나무(Distylium racemosom) 추출물 및 진달래(Rhododendron mucronulatum) 추출물로 구성된 군으로부터 선택되는 하나 이상의 추출물을 유효성분으로 포함하는 Th2-매개 면역 질환의 예방, 개선 또는 치료용 조성물에 관한 것이다. 본 발명에 따르면, 상기 추출물은 IL-4 생성 억제, 알레르겐의 장상피세포 통과 억제 및 비만세포의 탈과립 억제 활성을 가짐으로 Th2-매개 면역 질환을 예방, 개선 또는 치료할 수 있다.

Подробнее
Номер записи: 13
21-01-2016 дата публикации

COMPOSITION COMPRISING PEDIOCOCCUS ACIDILACTICI AS ACTIVE INGREDIENT FOR PREVENTING, ALLEVIATING OR TREATING Th1-MEDIATED IMMUNE DISEASES OR Th2-MEDIATED IMMUNE DISEASES

Номер: KR1020160008058A
Автор: LEE, SO YOUNG, SHON, DONG HWA, SHIN, HEE SOON, NAM, YOUNG DO, DO, JEONG RYONG, JUNG, SUNG KEUN, CHUNG, MIN YU, EOM, JI EUN, IM, SIN HYEOG
Принадлежит:

The present invention relates to a composition comprising Pediococcus acidilactici as an active ingredient for preventing, alleviating, or treating Th1-mediated immune diseases or Th2-mediated immune diseases. Pediococcus acidilactici of the present invention is capable of effectively controlling Th1-mediated immune diseases or Th2-mediated immune diseases, by activing control T cells, increasing generation of IL-10 which is anti-inflammatory cytokine, inhibiting generation IL-12 which is immune-activating cytokine, and reducing an amount of IgE antibodies produced. Therefore, the composition can be used as an anti-allergic composition and an anti-inflammatory composition. COPYRIGHT KIPO 2016 ...

Подробнее
Номер записи: 14
02-08-2016 дата публикации

바실러스 아밀로리퀴페시언스 26N 균주를 유효성분으로 포함하는 항알레르기성 조성물

Номер: KR0101644593B1
Автор: 이소영, 손동화, 신희순, 임성일, 도정룡, 정성근, 정민유, 엄지은, 임신혁, 김정은, 박선희
Принадлежит: 한국식품연구원

... 본 발명은 바실러스 아밀로리퀴페시언스 26N 균주(기탁번호 KCCM 11287P)를 유효성분으로 포함하는 항알레르기성 조성물를 제공한다. 본 발명은 항알레르기 활성을 갖는 바실러스 아밀로리퀴페시언스 26N 균주를 제공한다. 본 발명의 바실러스 아밀로리퀴페시언스 26N 균주는 조절 T 세포를 활성화 시키고 항염증 사이토카인인 IL10을 증가시킴으로써 알레르기를 효과적으로 제어할 수 있다.

Подробнее
Номер записи: 15
02-03-2016 дата публикации

COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING ALLERGY DISEASES, COMPRISING CIMICIFUGA ACERINA EXTRACT

Номер: KR1020160022847A
Автор: SHON, DONG HWA, SHIN, HEE SOON, CHAI, OK HEE, BAE, MIN JUNG, CHOI, DAE WOON, JUNG, SUN YOUNG, SEE, HYE JEONG, LEE, SO YOUNG, DO, JEONG RYONG, JUNG, SUNG KEUN, CHUNG, MIN YU
Принадлежит:

The present invention relates to a composition for preventing, alleviating, or treating Th2-mediated immunological diseases, comprising one or more selected from the group consisting of a Mollugo pentaphylla extract, an Alisma plantago-aquatica, an Eaeocarpus sylvestris extract, and a Cimicifuga acerina extract, as an active ingredient. According to the present invention, the extracts have effects of preventing, alleviating, or treating Th2-mediated immunological diseases by having suppression activities of IL-4 generation and mast cell degranulation. COPYRIGHT KIPO 2016 (AA) Food + Buffer (BB) Food + C48/80 (CC) Mollugo pentaphylla mg/ml ...

Подробнее
Номер записи: 16
07-01-2016 дата публикации

COMPOSITION FOR PREVENTING, MITIGATING OR TREATING OF Th2-MEDIATED IMMUNE DISEASES COMPRISING RHAMNUS DAVURICA PALL. EXTRACT, CHRYSOSPLENIUM GRAYANUM MAXIM. EXTRACT, PODOCARPUS MACROPHYLLUS EXTRACT, DISTYLIUM RACEMOSUM SIEBOLD & ZUCC. EXTRACT OR RHODODENDRON MUCRONULATUM TURCZ. EXTRACT

Номер: KR1020160001804A
Автор: SHON, DONG HWA, SHIN, HEE SOON, CHAI, OK HEE, BAE, MIN JUNG, CHOI, DAE WOON, JUNG, SUN YOUNG, SEE, HYE JEONG, LEE, SO YOUNG, DO, JEONG RYONG, JUNG, SUNG KEUN, CHUNG, MIN YU
Принадлежит:

The present invention relates to a composition for preventing, mitigating, or treating Th2-mediated immune diseases comprising one or more extracts selected from the group consisting of a Rhamnus davurica Pall. extract, a Chrysosplenium grayanum Maxim.extract, a Podocarpus macrophyllus extract, a Distylium racemosum Siebold & Zucc. extract, and a Rhododendron mucronulatum Turcz. extract. According to the present invention, the extracts controls IL-4 generation, controls penetration of an allergen into intestinal epithelial cells, and controls degranulation of mast cells, thereby preventing, mitigating, or treating Th2-mediated immune diseases. COPYRIGHT KIPO 2016 ...

Подробнее
Номер записи: 17
07-07-2016 дата публикации

Composition for Preventing, Improving or Treating of Ｔｈ1-mediated Immune Disease or Ｔｈ2-mediated Immune Disease Comprising Extracts from Pediococcus acidilactici as an Active Ingredients

Номер: KR0101635997B1
Автор: 이소영, 손동화, 신희순, 남영도, 도정룡, 정성근, 정민유, 엄지은, 임신혁
Принадлежит: 한국식품연구원

... 본 발명은 페디오코쿠스 에시디락티시(Pediococcus acidilactici)를 유효성분으로 포함하는 Th1-매개 면역 질환 또는 Th2-매개 면역 질환의 예방, 개선 또는 치료용 조성물에 관한 것이다. 본 발명의 페디오코쿠스 에시디락티시는 조절 T 세포를 활성화시키고, 항염증 사이토카인인 IL-10 생성을 증가시키며, 면역활성 사이토카인인 IL-12 생성을 억제시키며, IgE 항체의 생성양을 감소시킴으로써 Th1-매개 면역 질환 또는 Th2-매개 면역 질환을 효과적으로 제어하는바 항알레르기성 조성물 및 항염증성 조성물로 사용이 가능한 이점이 있다.

Подробнее
Номер записи: 18
07-01-2016 дата публикации

COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING TH1-MEDIATED IMMUNE DISEASES OR TH2-MEDIATED IMMUNE DISEASES INCLUDING EXTRACTS FROM DAVALLIA MERIESIL, EXTRACTS FROM EMPETRUM NIGRUM VAR. JAPONICUM K. KOCH, EXTRACTS FROM NARCISSUS TAZETTA L. VAR. CHINENSIS ROEM., EXTRACTS FROM MARSILEA QUADRIFOLIA L., EXTRACTS FROM NERIUM INDICUM MILL., EXTRACTS FROM POTENTILLA DISCOLOR BUNGE, OR EXTRACTS FROM GLEICHENIA JAPONICA SPRENG

Номер: KR1020160001803A
Автор: SHON, DONG HWA, SHIN, HEE SOON, CHAI, OK HEE, BAE, MIN JUNG, CHOI, DAE WOON, JUNG, SUN YOUNG, SEE, HYE JEONG, LEE, SO YOUNG, DO, JEONG RYONG, JUNG, SUNG KEUN, CHUNG, MIN YU
Принадлежит:

The present invention relates to a composition for preventing, alleviating, or treating Th1-mediated immune diseases or Th2-mediated immune diseases, which includes one or more extracts selected from the group consisting of extracts from Davallia meriesil, extracts from Empetrum nigrum var. japonicum K. Koch, extracts from Narcissus tazetta L. var. chinensis Roem., extracts from Marsilea quadrifolia L., extracts from Nerium indicum Mill., extracts from Potentilla discolor Bunge, and extracts from Gleichenia japonica Spreng. as active ingredients. According to the present invention, the extracts may prevent, alleviate, or treat Th1-mediated immune diseases or Th2-mediated immune diseases by having activities in controlling IL-4 generation, controlling passage of intestinal epithelial cell of allergen, controlling degranulation of mast cells, and inducing differentiation into Treg cells. COPYRIGHT KIPO 2016 ...

Подробнее
Номер записи: 19
03-08-2016 дата публикации

락토바실러스 카제이(Lactobacillus casei)를 유효성분으로 포함하는 Ｔｈ1-매개 면역 질환 또는 Ｔｈ2-매개 면역 질환의 예방, 개선 또는 치료용 조성물

Номер: KR0101644594B1
Автор: 이소영, 손동화, 신희순, 임성일, 도정룡, 정성근, 정민유, 엄지은, 임신혁
Принадлежит: 한국식품연구원

... 본 발명은 락토바실러스 카제이(Lactobacillus casei)를 유효성분으로 포함하는 Th1-매개 면역 질환 또는 Th2-매개 면역 질환의 예방, 개선 또는 치료용 조성물에 관한 것이다. 본 발명의 락토바실러스 카제이는 조절 T 세포를 활성화시키고, 항염증 사이토카인인 IL-10 생성을 증가시키며, 면역활성 사이토카인인 IL-12 생성을 억제시키며, IgE 항체의 생성양을 감소시킴으로써 Th1-매개 면역 질환 또는 Th2-매개 면역 질환을 효과적으로 제어하는바 항알레르기성 조성물 및 항염증성 조성물로 사용이 가능한 이점이 있다.

Подробнее
Номер записи: 20
10-03-2016 дата публикации

COMPOSITION, CONTAINING EMPETRUM NIGRUM VAR. JAPONICUM EXTRACT, EXTRACT OF MARSILEA QUADRIFOLIA, EXTRACT OF POTENTILLA DISCOLOR, OR EXTRACT OF GLEICHENIA JAPONICA, FOR PREVENTING, ALLEVIATING, OR TREATING INFLAMMATORY DISEASES OR ALLERGIC DISEASES

Номер: KR1020160027964A
Автор: SHON, DONG HWA, SHIN, HEE SOON, CHAI, OK HEE, BAE, MIN JUNG, CHOI, DAE WOON, JUNG, SUN YOUNG, SEE, HYE JEONG, LEE, SO YOUNG, DO, JEONG RYONG, JUNG, SUNG KEUN, CHUNG, MIN YU
Принадлежит:

The present invention relates to a composition for preventing, alleviating, or treating Th1-mediated immune diseases or Th2-mediated immune diseases, the composition containing, as an active ingredient, at least one extract selected from the group consisting of an extract of Davallia meriesil, an extract of Empetrum nigrum var. japonicum, an extract of Narcissus tazetta var. chinensis, an extract of Marsilea quadrifolia, an extract of Nerium indicum, an extract of Pontentilla discolor, and an extract of Gleichenia japonica. According to the present invention, the composition can prevent, alleviate, or treat Th1-mediated immune diseases or Th2-mediated immune diseases by having activities to inhibit the production of IL-4, inhibit the passage of allergen through intestinal epithelial cells, inhibit the degranulation of mast cells, and induce the differentiation into Treg cells. COPYRIGHT KIPO 2016 ...

Подробнее
Номер записи: 21
20-09-2016 дата публикации

COMPOSITION INCLUDING SARCODON ASPARATUS EXTRACT FOR PREVENTING OR TREATING LIVER DISEASES

Номер: KR1020160108771A
Автор: KIM, HYUN KU, DO, JEONG RYONG, CHUNG, MIN YU
Принадлежит:

The present invention relates to a pharmaceutical composition for preventing or treating liver diseases, wherein the pharmaceutical composition includes a Sarcodon asparatus 40 to 80 wt% ethanol extract obtained by microwaves, or a fraction thereof; a method for preventing or treating liver diseases, wherein the method comprises a step of administrating the composition to an entity excluding a human; and a health functional food for preventing or improving liver diseases, wherein the health functional food includes the extract or the fragment thereof. A Sarcodon asparatus ethanol extract obtained by microwaves according to the present invention reduces an activity of ALT increased by LPS treatment and reduces levels NO and 3-nitrotyrosine caused by damage to a liver, thereby being used in preventing or treating liver diseases. COPYRIGHT KIPO 2016 ...

Подробнее
Номер записи: 22
12-05-2017 дата публикации

붓순나무 추출물을 포함하는 알레르기 질환의 예방, 개선 또는 치료용 조성물

Номер: KR0101732031B1
Автор: 손동화, 신희순, 채옥희, 배민정, 최대운, 정선영, 시혜정, 이소영, 도정룡, 정성근, 정민유
Принадлежит: 한국식품연구원

... 본 발명은 미나리아재비(Ranunculus japonicus) 추출물, 붓순나무(Illicium religiosum) 추출물, 홀아비꽃대(Chloranthus japonicus) 추출물 및 두충(Eucommia ulmoides) 추출물로 구성된 군으로부터 선택되는 하나 이상의 추출물을 유효성분으로 포함하는 Th2-매개 면역 질환의 예방, 개선 또는 치료용 조성물에 관한 것이다. 본 발명에 따르면, 상기 추출물은 IL-4 생성 억제 및 비만세포의 탈과립 억제 활성을 가짐으로 Th2-매개 면역 질환을 예방, 개선 또는 치료할 수 있다.

Подробнее
Номер записи: 23
21-01-2016 дата публикации

COMPOSITION COMPRISING LACTOBACILLUS PARACASEI AS ACTIVE INGREDIENT FOR PREVENTING, ALLEVIATING OR TREATING Th1-MEDIATED IMMUNE DISEASES OR Th2-MEDIATED IMMUNE DISEASES

Номер: KR1020160008060A
Автор: LEE, SO YOUNG, SHON, DONG HWA, SHIN, HEE SOON, PARK, SO LIM, DO, JEONG RYONG, JUNG, SUNG KEUN, CHUNG, MIN YU, EOM, JI EUN, IM, SIN HYEOG
Принадлежит:

The present invention relates to a composition comprising Lactobacillus paracasei as an active ingredient for preventing, alleviating, or treating Th1-mediated immune diseases or Th2-mediated immune diseases. Lactobacillus paracasei of the present invention is capable of effectively controlling Th1-mediated immune diseases or Th2-mediated immune diseases, by activing control T cells, increasing generation of IL-10 which is anti-inflammatory cytokine, and inhibiting generation IL-12 which is immune-activating cytokine. Therefore, the composition can be used as an anti-allergic composition and an anti-inflammatory composition. COPYRIGHT KIPO 2016 ...

Подробнее
Номер записи: 24