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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 18. Отображено 18.
11-02-2016 дата публикации

NOVEL BIOMARKER FOR PREDICTING SENSITIVITY OF PARP INHIBITOR AND USAGE THEREOF

Номер: KR1020160014565A
Автор: KIM, TAE WON, JIN, DONG HOON, HONG, SEUNG WOO, MOON, JAI HEE, SHIN, JAE SIK, HWANG, IH YEON, KIM, JEONG HEE, LEE, HA REUM, CHOI, EUN KYOUNG, KIM, SEUNG MI, JUNG, SOO A, HA, SEUNG HEE, LEE, DAE HEE, LEE, EUN YOUNG, LEE, SEUL, LEE, JUNG SHIN, CHOI, EUN KYUNG, LEE, JAE LYUN, HONG, YONG SANG, KIM, KYU PYO, KIM, JEONG EUN, PARK, SEONG JOON, KIM, BONG CHOEL
Принадлежит:

The present invention relates to a novel biomarker for predicting the sensitivity of a poly ADP ribose polymerase (PARP) inhibitor and the usage thereof. More particularly, the present invention provides: a biomarker for predicting the sensitivity of a PARP inhibitor containing DNA-dependent protein kinase (DNA-PK) or p53 genes; a composition for predicting the sensitivity of the PARP inhibitor containing medications for measuring the expression level of genes in the biomarker or the expression level of protein in the genes; a kit for predicting the sensitivity of the PARP inhibitor containing the composition; a method of predicting the sensitivity of the PARP inhibitor; a sensitivity promotor for the PARP inhibitor; and a pharmaceutical composition for treating or preventing cancer, including the sensitivity promotor and the PARP inhibitor as active components. An effect of predicting the sensitivity of the PARP inhibitor is great, so the present invention can be usefully utilized as a ...

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Номер записи: 1
22-08-2018 дата публикации

선택분사 소화기

Номер: KR0101890517B1
Автор: 민승남, 이예림, 이승엽, 정수아, 이규홍, 성용수
Принадлежит: 신성대학 산학협력단

... 본 발명의 일 실시예에 따르는, 선택분사 소화기는, 일면에 야광 식별부가 형성되고, 소화액이 분사되는 제1 분사부가 일 측에 형성되는 바디, 상기 바디의 타 측에 형성되고, 회전하면서 상기 분사액을 분사하도록 형성되는 제2 분사부, 상기 제1 분사부의 일 측에 형성되어 상기 제1 분사부를 개폐하도록 동작하는 제1 밸브, 상기 제2 분사부의 일 측에 형성되어 상기 제2 분사를 개폐하도록 동작하는 제2 밸브 및 무선통신할 수 있도록 형성되어, 전송받는 신호에 따라 상기 제1 및 제2 밸브들을 선택적으로 개폐할 수 있도록 제어하는 제어부를 포함하는 것을 특징으로 한다.

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Номер записи: 2
12-07-2017 дата публикации

ARTICLE FOR MEASURING BODY HORIZONTALITY

Номер: KR1020170081385A
Автор: KIM, SUE JUNG, CHUNG, SU A
Принадлежит:

The present invention relates to an article for measuring body horizontality. A flowable material is contained in a sealed tube. The height of the flowable material in the tube when the sealed tube is horizontal is marked on the tube. When the tube is tilted downward in one direction, the flowable material moves in the downward tilted direction of the tube. Therefore, people of all ages can easily check or measure the horizontality of their body including their shoulders. COPYRIGHT KIPO 2017 ...

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Номер записи: 3
06-09-2017 дата публикации

PARP 및 탄키라제 동시 저해제에 대한 감수성 결정 방법

Номер: KR0101775356B1
Автор: 김태원, 진동훈, 홍승우, 문재희, 신재식, 김정희, 황이연, 최은경, 김승미, 정수아, 이대희, 이은영, 이정신, 홍용상, 김규표, 김정은, 김봉철
Принадлежит: 재단법인 아산사회복지재단

... 본 발명은 PARP(Poly ADP Ribose Polymerase) 및 탄키라제(tankyrase) 동시 저해제에 대한 감수성 결정 방법에 관한 것이다. 본 발명에 따르면, PARP 및 탄키라제 동시 저해제에 대한 감수성을 갖는 환자군을 분류함으로써 대장암 치료 효과를 극대화 할 수 있다.

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Номер записи: 4
13-08-2018 дата публикации

SELECTIVE INJECTION TYPE FIRE EXTINGUISHER

Номер: KR1020180090404A
Автор: MIN, SEUNG NAM, LEE, YE RIM, LEE, SEUNG YEOB, JEONG, SU A, LEE, GYU HONG, SUNG, YONG SOO
Принадлежит:

According to one embodiment of the present invention, provided is a selective injection type fire extinguisher, which comprises: a body having a luminous identification unit formed on one surface and having a first injection unit for injecting digestive fluids formed on one side; a second injection unit formed on the other side of the body and rotationally injecting injected fluids; a first valve formed on one side of the first injection unit and moving to open and close the first injection unit; a second valve formed on one side of the second injection unit and moving to open and close the second injection unit; and a control unit performing wireless communications and controlling the first and second valves to selectively open and close the valves in accordance with a transmitted signal. Accordingly, the position of the fire extinguisher can be easily identified in case of fire. COPYRIGHT KIPO 2018 (110) Fire extinguisher (121) First valve (131) Second valve (140) Emergency auxiliary ...

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Номер записи: 5
11-03-2016 дата публикации

BIOMARKER FOR PREDICTING SENSITIVITY TO PROTEIN KINASE INHIBITOR AND USE OF SAME

Номер: KR1020160028399A
Автор: KIM, TAE WON, JIN, DONG HOON, HONG, SEUNG WOO, MOON, JAI HEE, SHIN, JAE SIK, LEE, HA REUM, CHOI, EUN KYOUNG, KIM, SEUNG MI, JUNG, SOO A, HA, SEUNG HEE, JUNG, HA NA, LEE, DAE HEE, JUNG, SEANG HWAN, LEE, JUNG SHIN, CHOI, EUN KYUNG, LEE, JAE LYUN, HONG, YONG SANG, KIM, KYU PYO, KIM, JEONG EUN, PARK, SEONG JOON, KIM, BONG CHOEL
Принадлежит:

The present invention relates to a biomarker for predicting sensitivity to a protein kinase inhibitor, and a use of the same. Provided are a marker, a composition, a kit, and a method for predicting sensitivity for a protein kinase inhibitor. According to the present invention, the biomarker excellently predicts sensitivity to a protein kinase inhibitor, thereby being used in cancer treatment. The biomarker for predicting sensitivity to a protein kinase inhibitor comprises active Recepteur d′origine nantais (RON). COPYRIGHT KIPO 2016 ...

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Номер записи: 6
04-02-2016 дата публикации

NOVEL BIOMARKER FOR PREDICTING SENSITIVITY TO PARP INHIBITOR, AND USE THEREOF

Номер: WO2016018089A1
Автор: KIM, Tae Won, JIN, Dong Hoon, HONG, Seung Woo, MOON, Jai Hee, SHIN, Jae Sik, HWANG, Ih Yeon, KIM, Jeong Hee, LEE, Ha Reum, CHOI, Eun Kyoung, KIM, Seung Mi, JUNG, Soo A, HA, Seung Hee, LEE, Dae Hee, LEE, Eun Young, LEE, Seul, LEE, Jung Shin, CHOI, Eun Kyung, LEE, Jae Lyun, HONG, Yong Sang, KIM, Kyu Pyo, KIM, Jeong Eun, PARK, Seong Joon, KIM, Bong Choel
Принадлежит:

The present invention relates to a novel biomarker for predicting sensitivity to a poly ADP ribose polymerase (PARP) inhibitor, and a use thereof, and more specifically, the present invention provides: a biomarker for predicting sensitivity to the PARP inhibitor, the biomarker comprising the p53 gene and/or the DNA-dependent protein kinase (DNA-PK) gene; a composition for predicting sensitivity to the PARP inhibitor, the composition comprising a pharmaceutical preparation for measuring the degree of expression of the gene in the biomarker, or the degree of expression of the protein of the gene; a kit for predicting sensitivity to the PARP inhibitor, the kit comprising the composition; a method for predicting sensitivity to the PARP inhibitor; a sensitivity enhancer for enhancing the sensitivity of a subject to the PARP inhibitor; and a pharmaceutical composition for preventing or treating cancer, the pharmaceutical composition comprising, as active ingredients, the sensitivity enhancer ...

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Номер записи: 7
04-02-2016 дата публикации

NOVEL BIOMARKER FOR PREDICTING SENSITIVITY TO EGFR-TARGETING AGENT, AND USE THEREOF

Номер: WO2016018087A1
Автор: KIM, Tae Won, JIN, Dong Hoon, HONG, Seung Woo, MOON, Jai Hee, SHIN, Jae Sik, HWANG, Ih Yeon, KIM, Jeong Hee, LEE, Ha Reum, CHOI, Eun Kyoung, KIM, Seung Mi, JUNG, Soo A, HA, Seung Hee, LEE, Dae Hee, LEE, Eun Young, LEE, Seul, LEE, Jung Shin, CHOI, Eun Kyung, LEE, Jae Lyun, HONG, Yong Sang, KIM, Kyu Pyo, KIM, Jeong Eun, PARK, Seong Joon, KIM, Bong Choel
Принадлежит:

The present invention relates to a novel biomarker for predicting sensitivity to an epidermal growth factor receptor (EGFR)-targeting agent, and a use thereof, and more specifically, the present invention provides: a biomarker for predicting sensitivity to the EGFR-targeting agent, the biomarker comprising the Recepteur d'Origine Nantais (RON) gene; a composition for predicting sensitivity to the EGFR-targeting agent, the composition comprising a pharmaceutical preparation for measuring the degree of expression of the gene in the biomarker, or the degree of expression or activity of the protein of the gene; a composition for enhancing sensitivity to the EGFR-targeting agent, the composition comprising, as an active ingredient, an inhibitor inhibiting the expression of the gene, or the expression or activity of the protein of the gene; a kit for predicting sensitivity to the EGFR-targeting agent, the kit comprising the compositions; and a method for predicting sensitivity to the EGFR-targeting ...

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Номер записи: 8
31-05-2018 дата публикации

단백질 키나제 억제제에 대한 감수성 예측용 바이오 마커 및 이의 용도

Номер: KR0101862719B1
Автор: 김태원, 진동훈, 홍승우, 문재희, 신재식, 이하름, 최은경, 김승미, 정수아, 하승희, 정하나, 이대희, 정승환, 이정신, 이재련, 홍용상, 김규표, 김정은, 박성준, 김봉철
Принадлежит: 웰마커바이오 주식회사

... 본 발명은 단백질 키나제 억제제에 대한 감수성 예측용 바이오 마커 및 이의 용도에 관한 것으로, 단백질 키나제 억제제에 대한 감수성 예측용 마커, 조성물, 키트 및 예측 방법을 제공한다. 본 발명에 따르면, 단백질 키나제 억제제에 대한 감수성 예측 효과가 우수하므로, 본 발명은 암 치료에 유용하게 이용될 수 있다.

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Номер записи: 9
04-02-2016 дата публикации

NOVEL BIOMARKER FOR PREDICTING SENSITIVITY TO MET INHIBITOR, AND USE THEREOF

Номер: WO2016018088A1
Автор: KIM, Tae Won, JIN, Dong Hoon, HONG, Seung Woo, MOON, Jai Hee, SHIN, Jae Sik, HWANG, Ih Yeon, KIM, Jeong Hee, LEE, Ha Reum, CHOI, Eun Kyoung, KIM, Seung Mi, JUNG, Soo A, HA, Seung Hee, LEE, Dae Hee, LEE, Eun Young, LEE, Seul, LEE, Jung Shin, CHOI, Eun Kyung, LEE, Jae Lyun, HONG, Yong Sang, KIM, Kyu Pyo, KIM, Jeong Eun, PARK, Seong Joon, KIM, Bong Choel
Принадлежит:

The present invention relates to a novel biomarker for predicting sensitivity to an MET inhibitor, and a use thereof, and more specifically, the present invention provides: a biomarker for predicting sensitivity to the MET inhibitor, the biomarker comprising the Immunoglobulin Superfamily member 1 (IGSF1, NM_001555.2) gene; a composition for predicting sensitivity to the MET inhibitor, the composition comprising a pharmaceutical preparation for measuring the degree of expression of the gene in the biomarker, or the degree of expression of the protein of the gene; a pharmaceutical composition for treating diseases related to the dysregulation of the MET signaling pathway, the pharmaceutical composition comprising, as an active ingredient, an inhibitor inhibiting the expression of the gene in the biomarker, or the expression or activity of the protein of the gene; a kit for predicting sensitivity to the MET inhibitor, the kit comprising the compositions; and a method for predicting sensitivity ...

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Номер записи: 10
02-04-2018 дата публикации

PARP 저해제에 대한 감수성 예측용 신규한 바이오 마커 및 이의 용도

Номер: KR0101844541B1
Автор: 김태원, 진동훈, 홍승우, 문재희, 신재식, 황이연, 김정희, 이하름, 최은경, 김승미, 정수아, 하승희, 이대희, 이은영, 이슬, 이정신, 이재련, 홍용상, 김규표, 김정은, 박성준, 김봉철
Принадлежит: 재단법인 아산사회복지재단

... 본 발명은 PARP 저해제에 대한 감수성을 예측하기 위한 신규한 바이오 마커 및 이의 용도에 관한 것으로, 보다 상세하게는, p53 유전자 및/또는 DNA-PK(DNA-dependent protein kinase) 유전자를 포함하는, PARP(poly ADP ribose polymerase) 저해제에 대한 감수성 예측용 바이오 마커; 상기 바이오 마커의 유전자 발현 수준; 또는 상기 유전자의 단백질의 발현 수준을 측정하는 제제를 포함하는, PARP 저해제에 대한 감수성 예측용 조성물; 상기 조성물을 포함하는 PARP 저해제에 대한 감수성 예측용 키트; PARP 저해제에 대한 감수성 예측 방법; 대상의 PARP 저해제에 대한 감수성 증진제; 및 상기 감수성 증진제 및 PARP 저해제를 유효성분으로 포함하는, 암의 예방 또는 치료용 약학적 조성물을 제공한다. 본 발명에 따르면, PARP 저해제에 대한 감수성 예측 효과가 우수하므로, 본 발명은 대장암 치료에 유용하게 이용될 수 있다.

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Номер записи: 11
15-05-2018 дата публикации

COSMETIC CONTAINER CAPABLE OF ABSORBING OIL

Номер: KR1020180050516A
Автор: JEONG, SU A
Принадлежит:

The present invention relates to a cosmetic container capable of absorbing oil, which can solve a sanitary problem that a puff is to be stored with facial oil attached thereon after conventional make-up, by adding a detachable oil control film to materials of a foundation cover and a cosmetic container support in order to make clean condition whenever the puff is used. In addition, the cosmetic container comprises: a cosmetic container mirror which has a round shape so that a user can see the face of a user during make-up; a cosmetic container puff which has a round shape and has a loop to insert fingers of the user thereinto for applying foundation and tapping the foundation on the face; a foundation cover and a cosmetic container support which can cover foundation to be stored, have an egg shape in order to put a cushion thereon, and are positioned between the mirror and the foundation; foundation which is formed inside a cotton ball and aims to make the face look brighter than before ...

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Номер записи: 12
11-02-2016 дата публикации

NOVEL BIOMARKER FOR PREDICTING SENSIBILITY TO MET INHIBITOR, AND USES THEREOF

Номер: KR1020160014564A
Автор: KIM, TAE WON, JIN, DONG HOON, HONG, SEUNG WOO, MOON, JAI HEE, SHIN, JAE SIK, HWANG, IH YEON, KIM, JEONG HEE, LEE, HA REUM, CHOI, EUN KYOUNG, KIM, SEUNG MI, JUNG, SOO A, HA, SEUNG HEE, LEE, DAE HEE, LEE, EUN YOUNG, LEE, SEUL, LEE, JUNG SHIN, CHOI, EUN KYUNG, LEE, JAE LYUN, HONG, YONG SANG, KIM, KYU PYO, KIM, JEONG EUN, PARK, SEONG JOON, KIM, BONG CHOEL
Принадлежит:

The present invention relates to a novel biomarker for predicting sensibility to an MET inhibitor, and uses thereof. Particularly, an objective of the present invention is to provide: a biomarker for predicting sensibility to an MET inhibitor containing immunoglobulin superfamily member 1 (IGSF1, NM_001555.2) genes; a sensibility predicting composition capable of sensing the sensibility of an MET inhibitor, containing a product for measuring the expression level of the genes of the biomarker or protein thereof; a pharmaceutical composition for curing diseases related to adjusting malfunctions in the path of transmitting signals of MET, containing an inhibitor which inhibits the expression or activeness of protein of the genes or the expression of the genes of the biomarker as an active component; a sensitivity predicting kit for an MET inhibitor containing the composition; and a method of predicting sensitivity to an MET inhibitor. The present invention is excellent in predicting the sensibility ...

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Номер записи: 13
11-02-2016 дата публикации

NOVEL BIOMARKER FOR PREDICTING SENSITIVITY TO EGFR-TARGETING AGENT AND USE THEREOF

Номер: KR1020160014563A
Автор: KIM, TAE WON, JIN, DONG HOON, HONG, SEUNG WOO, MOON, JAI HEE, SHIN, JAE SIK, HWANG, IH YEON, KIM, JEONG HEE, LEE, HA REUM, CHOI, EUN KYOUNG, KIM, SEUNG MI, JUNG, SOO A, HA, SEUNG HEE, LEE, DAE HEE, LEE, EUN YOUNG, LEE, SEUL, LEE, JUNG SHIN, CHOI, EUN KYUNG, LEE, JAE LYUN, HONG, YONG SANG, KIM, KYU PYO, KIM, JEONG EUN, PARK, SEONG JOON, KIM, BONG CHOEL
Принадлежит:

The present invention relates to a novel biomarker for predicting sensitivity to an epidermal growth factor receptor (EGRF)-targeting agent, and use thereof. More specifically, the present invention provides: the biomarker for predicting sensitivity to the (EGRF)-targeting agent; a composition for predicting sensitivity to the (EGRF)-targeting agent which includes an agent for measuring a level of gene expression of the biomarker, expression of protein of the genes, or an activity level of the gene; a composition for increasing sensitivity to the (EGRF)-targeting agent which includes an agent for suppressing expression of the gene, expression of the protein of the gene, or activity of the gene; a kit for predicting sensitivity to the (EGRF)-targeting agent including the composition; and a method for predicting sensitivity to the (EGRF)-targeting agent. According to the present invention, the biomarker of the present invention has an excellent effect of predicting sensitivity to the (EGRF ...

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Номер записи: 14
10-04-2018 дата публикации

DEVICE FOR DIAGNOSING RISK OF LABOR WORK

Номер: KR101847332B1
Автор: MIN, SEUNG NAM, JEONG, SU A, MYEONG, JAE SEUNG, LEE, YE RIM, LEE, SEUNG YEOB, LEE, GYEONG ROK
Принадлежит: SHINSUNG COLLEGE

The present invention provides a device for diagnosing a risk of a labor work which derives a behavior change rate by time according to a work and can diagnose cumulative fatigue of an attacher. According to an embodiment of the present invention, the device for diagnosing a risk of a labor work comprises: a sensor part formed to detect behavior of the attacher according to the work; and a control part recognizing the behavior of the attacher based on hourly data received from the sensor part, deriving the behavior change rate according to the behavior, and diagnosing the cumulative fatigue and a risk of the work of the attacher. The control part diagnoses the risk of the work if the cumulative fatigue is equal to or greater than a predetermined value based on statistics of the work according to a body shape of the attacher, and re-diagnoses the cumulative fatigue and the risk of the work by weighing the changed value, if the change per unit time of the fatigue changes by more than or equal ...

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Номер записи: 15
10-03-2016 дата публикации

BIOMARKER FOR PREDICTING SENSITIVITY TO PROTEIN KINASE INHIBITOR AND USE THEREOF

Номер: WO2016036172A1
Автор: KIM, Tae Won, JIN, Dong Hoon, HONG, Seung Woo, MOON, Jai Hee, SHIN, Jae Sik, LEE, Ha Reum, CHOI, Eun Kyoung, KIM, Seung Mi, JUNG, Soo A, HA, Seung Hee, JUNG, Ha Na, LEE, Dae Hee, JUNG, Seang Hwan, LEE, Jung Shin, CHOI, Eun Kyung, LEE, Jae Lyun, HONG, Yong Sang, KIM, Kyu Pyo, KIM, Jeong Eun, PARK, Seong Joon, KIM, Bong Choel
Принадлежит:

The present invention relates to a biomarker for predicting sensitivity to a protein kinase inhibitor and a use thereof, and provides a marker for predicting sensitivity to a protein kinase inhibitor, a composition, a kit, and a prediction method. According to the present invention, an effect of predicting sensitivity to a protein kinase inhibitor is excellent, and thus the present invention can be useful for cancer treatment.

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Номер записи: 16
25-01-2018 дата публикации

MET 저해제에 대한 감수성 예측용 신규한 바이오 마커 및 이의 용도

Номер: KR0101811731B1
Автор: 김태원, 진동훈, 홍승우, 문재희, 신재식, 황이연, 김정희, 이하름, 최은경, 김승미, 정수아, 하승희, 이대희, 이은영, 이슬, 이정신, 이재련, 홍용상, 김규표, 김정은, 박성준, 김봉철
Принадлежит: 재단법인 아산사회복지재단

... 본 발명은 MET 저해제에 대한 감수성 예측용 신규한 바이오 마커 및 이의 용도에 관한 것으로, 보다 상세하게는, IGSF1(Immunoglobulin Superfamily member 1, NM_001555.2) 유전자를 포함하는 MET 저해제에 대한 감수성 예측용 바이오 마커; 상기 바이오 마커 유전자 발현 수준 또는 이의 단백질의 발현 수준을 측정하는 제제를 포함하는 MET 저해제에 대한 감수성 예측용 조성물; 상기 바이오 마커 유전자의 발현 또는 상기 유전자의 단백질의 발현 또는 활성을 억제하는 억제제를 유효성분으로 포함하는 MET 신호전달 경로의 조절이상과 관련된 질환의 치료용 약학적 조성물; 상기 조성물을 포함하는 MET 저해제에 대한 감수성 예측용 키트; 및 MET 저해제에 대한 감수성 예측 방법을 제공한다. 본 발명에 따르면, 본 발명은 위암 또는 폐암에서의 MET 저해제제에 대한 감수성 예측 효과가 우수하므로, 본 발명은 위암 또는 폐암 치료에 유용하게 이용될 수 있다.

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Номер записи: 17
16-01-2017 дата публикации

METHOD FOR DETERMINING SUSCEPTIBILITY TO DUAL INHIBITOR AGAINST PARP AND TANKYRASE

Номер: KR1020170005627A
Автор: KIM, TAE WON, JIN, DONG HOON, HONG, SEUNG WOO, MOON, JAI HEE, SHIN, JAE SIK, KIM, JEONG HEE, HWANG, IH YEON, CHOI, EUN KYOUNG, KIM, SEUNG MI, JUNG, SOO A, LEE, DAE HEE, LEE, EUN YOUNG, LEE, JUNG SHIN, CHOI, EUN KYUNG, HONG, YONG SANG, KIM, KYU PYO, KIM, JEONG EUN, KIM, BONG CHOEL
Принадлежит:

The present invention relates to a method for determining susceptibility to a dual inhibitor against poly(ADP-ribose) polymerase (PARP) and tankyrase. According to the present invention, a patient group having susceptibility to a dual inhibitor against PARP and tankyrase is classified, so the colorectal cancer treatment effect can be maximized. COPYRIGHT KIPO 2017 ...

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Номер записи: 18