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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 11. Отображено 11.
06-06-2013 дата публикации

DRUG CONJUGATE COMPRISING DRUG LINKED TO HUMAN C-MET ANTIBODY, AND USE THEREFOR

Номер: WO2013081379A1
Автор: PARK, Young Woo, JO, Ki Won, JO, Sun Jeong, HYUN, Soon Sil, PARK, Jae Eun, YOO, Seok Ho, JANG, Myeoung Hee, KIM, Hye Nan, PARK, Chan Woong
Принадлежит:

The present invention relates to a drug conjugate comprising a cytotoxic drug linked to a c-Met specific human antibody. More specifically, the present invention relates to: a drug conjugate comprising a cytotoxic drug linked to a c-Met specific human antibody; a pharmaceutical composition for cancer treatment comprising the drug conjugate; and a cancer treatment method comprising a step in which the drug conjugate or pharmaceutical composition is administered to an individual.

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Номер записи: 1
21-12-2016 дата публикации

COSMETIC COMPOSITION CONTAINING BOILED SEA CUCUMBER EXTRACT OR A FRACTION THEREOF AS ACTIVE INGREDIENT

Номер: KR1020160146406A
Автор: KIM, SO JUNG, LEE, SANG CHOL, KWON, EUN HYE, HONG, SUN MEE, JO, SUN JUNG
Принадлежит:

The present invention relates to a cosmetic composition which contains boiled sea cucumber extract or a fraction thereof as an active ingredient and has skin-whitening and wrinkle-ameliorating effects. COPYRIGHT KIPO 2016 ...

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Номер записи: 2
17-06-2010 дата публикации

NOVEL USE OF THE LOC284422 GENE

Номер: WO2010067969A2
Автор: WON, Misun, CHUNG, Kyung-Sook, CHO, Sun-Jung, CHOI, Shin-Jung, YEOM, Young Il, KIM, Seon-Young, SONG, Kyung Bin, LEE, Hee Gu, SONG, Eun Young, KIM, Young Ho, CHUN, Ho Kyung, KIM, Moon Hee, JUNG, Kyeong-Eun, OH, Yu-Kyoung
Принадлежит:

The present invention provides a composition for cancer diagnosis or anti-cancer drug screening containing the LOC284422 gene or an antibody against the proteins expressed by LOC284422 gene, to a cancer treatment composition containing an inhibitor for said gene, an inhibitor for the proteins expressed by said gene, and a pharmaceutically acceptable carrier, and to a kit for cancer diagnosis containing the LOC284422 gene or one or more of the proteins expressed by the LOC284422 gene. The LOC284422 gene of the present invention is largely expressed in cancer cells, and increases the growth speed of normal cells. Therefore, the inhibition of the expression of this gene leads to the inhibition of the growth of cancer cells. Accordingly, the LOC284422 gene can be used as a target gene for the diagnosis of therapeutic agents for different types of cancer.

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Номер записи: 3
15-03-2016 дата публикации

Pharmaceutical composition comprising ATG12 inhibitor for preventing or treating Alzheimer's disease

Номер: KR0101603195B1
Автор: 고영호, 조선정, 윤상문, 조철만, 이대훈
Принадлежит: 대한민국

... 본 발명은 ATG12 유전자의 발현 또는 활성 억제제를 유효성분으로 포함하는 알츠하이머병 예방 또는 치료용 약학적 조성물, 진단 방법, 및 진단 키트에 관한 것으로, 구체적으로 본 발명의 ATG12의 발현 또는 활성 억제제를 이용한 알츠하이머병의 치료 또는 예방용 약학적 조성물은 SUMO1에 의한 ATG12 발현 증가를 억제시킴으로써 아밀로이드 베타 수준을 감소시키므로 알츠하이머병 치료 또는 예방에 유용하게 사용될 수 있다.

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Номер записи: 4
31-12-2015 дата публикации

PHARMACEUTICAL COMPOSITION COMPRISING ATG12 GENE EXPRESSION OR ACTIVATION INHIBITOR AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING ALZHEIMER

Номер: KR1020150146181A
Автор: KOH, YOUNG HO, CHO, SUN JUNG, YUN, SANG MOON, JO, CHUL MAN, LEE, DAE HOON
Принадлежит:

The present invention relates to a pharmaceutical composition, a diagnosis method, and a diagnosis kit, comprising an ATG12 gene expression or activation inhibitor as an active ingredient for preventing or treating Alzheimer′s disease. Specifically, the pharmaceutical composition for treating or preventing Alzheimer′s disease by using the ATG12 expression or activation inhibitor of the present invention can be usefully used for treating or preventing Alzheimer′s disease by inhibiting increase in ATG12 expression by SUMO1 and reducing the level of amyloid beta. COPYRIGHT KIPO 2016 ...

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Номер записи: 5
22-09-2011 дата публикации

DUAL ANTAGONIST FOR TNF-Α AND IL-21 FOR PREVENTING AND TREATING AUTOIMMUNE DISEASES

Номер: WO2011115458A3
Автор: PARK, Young Woo, JO, Ki Won, YOO, Srok Ho, YU, Jung, YOON, Sun-Ha, PARK, Ji Hyun, SONG, Eun Jung, LEE, Jong-Ho, SEO, Min Ji, CHO, Sun Jung, CHO, Mi La, KIM, Ho Youn, PARK, Mi Kyung, OH, Hye Jwa, PARK, Jin Sil, WOO, Yun Ju, BYUN, Jae Kyeong, RYU, Jun Geol
Принадлежит:

The present invention relates to a TNFR2-IL21R fusion protein acting as a dual antagonist for TNF-α and IL-21. More specifically, a composition containing the dual antagonist (TNFR2-IL21R fusion protein) for TNF-α and IL-21 which are known as the main cause of autoimmune arthritis, one of autoimmune diseases, more remarkably reduces the secretion of inflammatory cytokine, increases the secretion of anti-inflammatory cytokine, and suppresses the differentiation of osteoclast compared with the case using TNFR2-Fc and IL21R-Fc single proteins. In addition, the composition treats arthritis of collagen-induced arthritis (CIA) mice and increases the expression of Treg cells, an immunosuppressive cell, thereby treating autoimmune arthritis. Therefore, the TNFR2-IL21R fusion protein according to the present invention can be used as an active ingredient of a composition for preventing and treating autoimmune diseases.

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Номер записи: 6
28-09-2017 дата публикации

SUMO2를 이용한 경도인지장애 또는 알츠하이머 질환 진단용 키트

Номер: KR0101781959B1
Автор: 고영호, 조선정, 윤상문, 조철만
Принадлежит: 대한민국

... 본 발명은 SUMO2를 이용한 경도인지장애 또는 알츠하이머 질환 진단용 키트에 관한 것으로, 구체적으로 경도인지장애군 및 알츠하이머 질환 환자군의 혈장내 SUMO2의 농도가 현저히 낮게 나타남을 확인함으로써, 상기 SUMO2 단백질을 마커로 이용하여, 특별한 징후 및 증상이 없어 초기진단이 어려운 경도인지장애 및 알츠하이머치매 진단에 유용하게 이용할 수 있다.

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Номер записи: 7
22-09-2011 дата публикации

DUAL ANTAGONIST FOR TNF-Α AND IL-21 FOR PREVENTING AND TREATING AUTOIMMUNE DISEASES

Номер: WO2011115458A2
Автор: PARK, Young Woo, JO, Ki Won, YOO, Srok Ho, YU, Jung, YOON, Sun-Ha, PARK, Ji Hyun, SONG, Eun Jung, LEE, Jong-Ho, SEO, Min Ji, CHO, Sun Jung, CHO, Mi La, KIM, Ho Youn, PARK, Mi Kyung, OH, Hye Jwa, PARK, Jin Sil, WOO, Yun Ju, BYUN, Jae Kyeong, RYU, Jun Geol
Принадлежит:

The present invention relates to a TNFR2-IL21R fusion protein acting as a dual antagonist for TNF-α and IL-21. More specifically, a composition containing the dual antagonist (TNFR2-IL21R fusion protein) for TNF-α and IL-21 which are known as the main cause of autoimmune arthritis, one of autoimmune diseases, more remarkably reduces the secretion of inflammatory cytokine, increases the secretion of anti-inflammatory cytokine, and suppresses the differentiation of osteoclast compared with the case using TNFR2-Fc and IL21R-Fc single proteins. In addition, the composition treats arthritis of collagen-induced arthritis (CIA) mice and increases the expression of Treg cells, an immunosuppressive cell, thereby treating autoimmune arthritis. Therefore, the TNFR2-IL21R fusion protein according to the present invention can be used as an active ingredient of a composition for preventing and treating autoimmune diseases.

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Номер записи: 8
17-06-2010 дата публикации

NOVEL USE OF THE LOC284422 GENE

Номер: WO2010067969A3
Автор: WON, Misun, CHUNG, Kyung-Sook, CHO, Sun-Jung, CHOI, Shin-Jung, YEOM, Young Il, KIM, Seon-Young, SONG, Kyung Bin, LEE, Hee Gu, SONG, Eun Young, KIM, Young Ho, CHUN, Ho Kyung, KIM, Moon Hee, JUNG, Kyeong-Eun, OH, Yu-Kyoung
Принадлежит:

The present invention provides a composition for cancer diagnosis or anti-cancer drug screening containing the LOC284422 gene or an antibody against the proteins expressed by LOC284422 gene, to a cancer treatment composition containing an inhibitor for said gene, an inhibitor for the proteins expressed by said gene, and a pharmaceutically acceptable carrier, and to a kit for cancer diagnosis containing the LOC284422 gene or one or more of the proteins expressed by the LOC284422 gene. The LOC284422 gene of the present invention is largely expressed in cancer cells, and increases the growth speed of normal cells. Therefore, the inhibition of the expression of this gene leads to the inhibition of the growth of cancer cells. Accordingly, the LOC284422 gene can be used as a target gene for the diagnosis of therapeutic agents for different types of cancer.

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Номер записи: 9
03-03-2016 дата публикации

DIAGNOSTIC KIT FOR MILD COGNITIVE IMPAIRMENT OR ALZHEIMER′S DISEASE USING SMALL UBIQUITIN-LIKE MODIFIER 2

Номер: KR1020160023340A
Автор: KOH, YOUNG HO, CHO, SUN JUNG, YUN, SANG MOON, JO, CHUL MAN
Принадлежит:

The present invention relates to a diagnostic kit for mild cognitive impairment or Alzheimer′s disease using small ubiquitin-like modifier 2 (SUMO2). More specifically, it has been found that the concentration of plasma SUMO2 in a patient group with mild cognitive impairment and Alzheimer′s disease is remarkably low. Thus, the SUMO2 protein can be used as a marker to diagnose mild cognitive impairment and Alzheimer′s disease which are hard to diagnose in advance since the diseases show no special signs or symptoms. COPYRIGHT KIPO 2016 (AA) SUMO2 concentrations(ng /ml) ...

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Номер записи: 10
12-05-2017 дата публикации

해삼 자숙액 또는 이의 분획물을 유효성분으로 포함하는 화장료 조성물

Номер: KR0101734873B1
Автор: 김소정, 이상철, 권은혜, 홍선미, 조선정
Принадлежит: 재단법인 경북해양바이오산업연구원, 이상철

... 본 발명은 해삼 자숙액 또는 이의 분획물을 유효성분으로 포함하며 미백 및 주름개선에 효능이 있는 화장료 조성물에 관한 것이다.

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Номер записи: 11