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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 24. Отображено 24.
28-12-2017 дата публикации

에키노크롬 A를 유효성분으로 함유하는 심근세포 분화유도용 조성물

Номер: KR0101813079B1
Автор: 한진, 허혜진, 김나리, 김형규
Принадлежит: 인제대학교 산학협력단

... 본 발명은 에키노크롬 A(Echinochrome A)를 유효성분으로 함유하는 배아줄기세포 유래 심근세포 분화촉진용 약학조성물에 관한 것으로, 보다 상세하게는 극피동물 성게류에서 추출된 에키노크롬 A는 세포독성을 나타내지 않으며 생쥐 배아줄기세포에서 심근세포로의 분화를 효과적으로 유도하는 것으로 확인됨에 따라 본 발명에 따른 에키노크롬 A를 유효성분으로 함유하는 조성물은 심근세포 분화유도용 조성물 또는 배지조성물로 제공될 수 있다.

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Номер записи: 1
02-11-2017 дата публикации

HETEROARYL COMPOUND COMPRISING NITROGEN, AND USE THEREOF

Номер: WO2017188694A1
Автор: KIM, Hong Woo, YOO, SangHee, KIM, Hyunwook, HEO, Hye Jin, LEE, Hong Bum, KOOK, Jiae, LEE, Young Woo, KIM, Sung Wuk
Принадлежит:

The present invention relates to a heteroaryl compound comprising nitrogen, and a use thereof and, more specifically, to: a compound exhibiting an excellent effect in the inhibition of cancer cell proliferation, cancer metastasis and recurrence; a preparation method therefor; and a pharmaceutical composition containing the same as an active ingredient. The compound according to the present invention exhibits an excellent effect of inhibiting cancer cell proliferation, cancer metastasis and recurrence even in a relatively low dosage compared to that of conventional drugs, thereby being usable in the treatment of various cancers such as uterine cancer, breast cancer, stomach cancer, brain cancer, rectal cancer, colorectal cancer, lung cancer, skin cancer, blood cancer, pancreatic cancer, renal cancer, prostate cancer, bladder cancer, and liver cancer, and in the inhibition of cancer cell proliferation and cancer metastasis.

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Номер записи: 2
04-10-2012 дата публикации

NOVEL CEPHALOSPORIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF

Номер: WO2012134184A8
Автор: CHO, Young Lag, YUN, Joung Yul, PARK, Chul Soon, CHAE, Sang Eun, LEE, Hyang Sook, OH, Kyuman, HEO, Hye Jin, KANG, Dae Hyuck, YANG, Young Jae, KWON, Hyun Jin, PARK, Tae Kyo, WOO, Sung Ho, KIM, Yong Zu
Принадлежит:

The present invention relates to a novel cephalosporin derivative indicated in chemical formula 1 of the description. In the chemical formula 1, X, Y, L, R1, R2 are identical as defined in the detailed explanation. In addition, the present invention relates an antibiotic medical composition containing the novel cephalosporin derivative of the chemical formula 1, a prodrug thereof, a hydrate thereof, a solvate thereof, an isomer thereof, and a pharmaceutically permitted salt thereof, as active ingredients. The novel cephalosporin derivative of the chemical formula 1, the prodrug thereof, the hydrate thereof, the solvate thereof, the isomer thereof, and the pharmaceutically permitted salt thereof have a wide antibacterial spectrum for resistant bacteria, have low toxicity, and in particular, show strong antibacterial effect on gram negative bacteria, and is thus useful as an antibiotic.

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Номер записи: 3
24-03-2017 дата публикации

신규한 세파로스포린 유도체 및 이를 함유하는 의약 조성물

Номер: KR0101719556B1
Автор: 조영락, 윤정율, 박철순, 채상은, 이향숙, 오규만, 허혜진, 강대혁, 양영재, 권현진, 박태교, 우성호, 김용주
Принадлежит: 주식회사 레고켐 바이오사이언스

... 본 발명은 하기 화학식 1로 표시되는 신규한 세파로스포린 유도체에 관한 것이다. (1) 상기 식에서, X, Y, L, R1, R2 는 발명의 상세한 설명에 정의된 바와 동일하다. 또한, 본 발명은 상기 화학식 1의 신규한 세파로스포린 유도체, 이의 프로드럭, 이의 수화물, 이의 용매화물, 이의 이성질체 및 이의 약제학적으로 허용되는 염을 유효성분으로 함유하는 항생제용 의약 조성물에 관한 것이다. 본 발명에 따른 신규한 세파로스포린 유도체, 이의 프로드럭, 이의 수화물, 이의 용매화물, 이의 이성질체 및 이의 약제학적으로 허용되는 염은 내성균에 대한 항균 스펙트럼이 넓고, 독성이 낮으며, 특히 그람음성균에 강한 항균효과를 나타내므로, 항생제로 유용하게 사용될 수 있다.

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Номер записи: 4
03-06-2015 дата публикации

PHARMACEUTICAL COMPOSITION CONTAINING N1-CYCLIC AMINE-N5-SUBSTITUTED BIGUANIDE COMPOUND FOR PREVENTING OR TREATING AGE-RELATED DISEASE OF COGNITIVE FUNCTION

Номер: KR1020150060099A
Автор: BANG, EUN YOUNG, LEE, BO YOUNG, SHIN, HEE SUP, LEE, JI SUN, HEO, HYE JIN
Принадлежит:

The present invention relates to a compound capable of activating AMPK. The present invention aims to provide use of the compound for alleviating, preventing, and treating cognitive function impairment or cognitive function disorders caused by aging. The compound is represented by Chemical formula 1. COPYRIGHT KIPO 2015 ...

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Номер записи: 5
27-11-2014 дата публикации

PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING FIBROSIS, COMPRISING N1-CYCLIC AMINE-N5-SUBSTITUTED BIGUANIDE DERIVATIVE AS ACTIVE INGREDIENT

Номер: WO2014189246A1
Автор: KIM, Sung Wuk, LEE, Soon Im, SONG, Yeon Jung, SHIN, Min Jae, OH, Kook Hwan, JU, Kyung Don, SHIN, Eun Kyoung, LEE, Ji Sun, HEO, Hye Jin, LEE, Hong Bum, KOOK, Ji Ae, KIM, Min Jeong, EUM, Hye Soun
Принадлежит:

The present invention provides a novel use of an N1-cyclic amine-N5-substituted biguanide derivative for preparing a medicine for preventing or treating fibrosis. The N1-cyclic amine-N5-substituted biguanide derivative according to the present invention is capable of effectively inhibiting fibrosis by effectively inhibiting EMT.

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Номер записи: 6
15-09-2017 дата публикации

COMPOSITION FOR INDUCING DIFFERENTIATION OF CARDIOMYOCYTES CONTAINING ECHINOCHROME A AS ACTIVE INGREDIENT

Номер: KR1020170104223A
Автор: HAN, JIN, HEO, HYE JIN, KIM, NA RI, KIM, HYOUNG KYU
Принадлежит:

The present invention relates to a pharmaceutical composition for promoting differentiation of cardiomyocytes derived from embryonic stem cells containing echinochrome A as an active ingredient. More specifically, echinochrome A extracted from echinoderm such as sea urchins does not cause cytotoxicity, and also effectively induces differentiation into cardiomyocytes in mouse embryonic stem cells. According to the present invention, the composition containing the echinochrome A as the active ingredient can be provided as culture medium compositions or compositions for inducing cardiomyocyte differentiation. COPYRIGHT KIPO 2017 ...

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Номер записи: 7
21-12-2016 дата публикации

구아니딘 화합물 및 그의 용도

Номер: KR1020160146852A
Автор: 김성욱, 김홍우, 유상희, 이지선, 허혜진, 이홍범, 국지애, 이영우, 김미정, 조웅
Принадлежит:

... 본 발명은 미토콘드리아의 산화적 인산화 (OXPHOS)를 억제하기 위한 구아니딘 화합물 및 그의 용도에 관한 것이다. 보다 구체적으로, 본 발명은 미토콘드리아의 산화적 인산화를 억제하고 세포 대사를 재프로그래밍함으로써 OXPHOS와 관련된 질환, 특히 암을 예방 또는 치료하기 위한 약학 조성물에 관한 것이다.

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Номер записи: 8
04-10-2012 дата публикации

NOVEL CEPHALOSPORIN DERIVATIVE AND MEDICAL COMPOSITION CONTAINING SAME

Номер: WO2012134184A2
Автор: CHO, Young Lag, YUN, Joung Yul, PARK, Chul Soon, CHAE, Sang Eun, LEE, Hyang Sook, OH, Kyuman, HEO, Hye Jin, KANG, Dae Hyuck, YANG, Young Jae, KWON, Hyun Jin, PARK, Tae Kyo, WOO, Sung Ho, KIM, Yong Zu
Принадлежит:

The present invention relates to a novel cephalosporin derivative indicated in chemical formula 1 of the description. In the chemical formula 1, X, Y, L, R1, R2 are identical as defined in the detailed explanation. In addition, the present invention relates an antibiotic medical composition containing the novel cephalosporin derivative of the chemical formula 1, a prodrug thereof, a hydrate thereof, a solvate thereof, an isomer thereof, and a pharmaceutically permitted salt thereof, as active ingredients. The novel cephalosporin derivative of the chemical formula 1, the prodrug thereof, the hydrate thereof, the solvate thereof, the isomer thereof, and the pharmaceutically permitted salt thereof have a wide antibacterial spectrum for resistant bacteria, have low toxicity, and in particular, show strong antibacterial effect on gram negative bacteria, and is thus useful as an antibiotic.

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Номер записи: 9
04-10-2012 дата публикации

NOVEL CEPHALOSPORIN DERIVATIVE AND MEDICAL COMPOSITION CONTAINING SAME

Номер: WO2012134184A3
Автор: CHO, Young Lag, YUN, Joung Yul, PARK, Chul Soon, CHAE, Sang Eun, LEE, Hyang Sook, OH, Kyuman, HEO, Hye Jin, KANG, Dae Hyuck, YANG, Young Jae, KWON, Hyun Jin, PARK, Tae Kyo, WOO, Sung Ho, KIM, Yong Zu
Принадлежит:

The present invention relates to a novel cephalosporin derivative indicated in chemical formula 1 of the description. In the chemical formula 1, X, Y, L, R1, R2 are identical as defined in the detailed explanation. In addition, the present invention relates an antibiotic medical composition containing the novel cephalosporin derivative of the chemical formula 1, a prodrug thereof, a hydrate thereof, a solvate thereof, an isomer thereof, and a pharmaceutically permitted salt thereof, as active ingredients. The novel cephalosporin derivative of the chemical formula 1, the prodrug thereof, the hydrate thereof, the solvate thereof, the isomer thereof, and the pharmaceutically permitted salt thereof have a wide antibacterial spectrum for resistant bacteria, have low toxicity, and in particular, show strong antibacterial effect on gram negative bacteria, and is thus useful as an antibiotic.

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Номер записи: 10
12-11-2015 дата публикации

SPEED CONTROLLING APPARATUS FOR PINCH ROLL AND DRIVING METHOD OF SAME

Номер: KR101568607B1
Автор: HEO, HYE JIN
Принадлежит: POSCO

The present invention provides a speed controlling apparatus for a pinch roll, and a method of driving the same. The speed controlling apparatus comprises: a pinch roll discharging a wire, and providing the wire to a winding device; a speed measuring part measuring a speed of a wire movement in real time, the wire moving from an entrance side of the roller to the pinch roll; and a pinch roll driving control part reducing a pinching speed of the pinch roll based on access of the movement speed when the movement speed exceeds a reference speed. According to the present invention, the wound shape of a tail part of the wire can be formed with good conditions such that the wound wire can be transferred by the conveyor belt or a coil can be prevented from being jammed in an accumulating device when the coil is accumulated. As such, non-operating time is reduced, thus increasing work efficiency. COPYRIGHT KIPO 2016 (30) Pinch roll driving controller (AA) Roller (BB) Pricision roller (CC) Winder ...

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Номер записи: 11
14-05-2015 дата публикации

BIGUANIDE COMPOUND AND USE THEREOF

Номер: KR1020150052419A
Автор: KIM HONG WOO, LEE, JI SUN, HEO, HYE JIN, LEE, HONG BUM, JEONG, JAE KAP, PARK, JI HYUN, KIM, SEO IL, LEE, YOUNG WOO
Принадлежит:

The present invention relates to a biguanide compound and a use thereof, and more specifically, to a biguanide derivative which exhibits superior effects of inhibiting cancer cell proliferation, cancer metastasis, and cancer relapse, to a preparing method thereof, and to a pharmaceutical composition containing the same as an active ingredient. COPYRIGHT KIPO 2015 ...

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Номер записи: 12
17-07-2017 дата публикации

기계적 박리성이 우수한 타이어 코드용 선재의 제조방법

Номер: KR0101758523B1
Автор: 허혜진, 양요셉
Принадлежит: 주식회사 포스코

... 빌렛을 열간 압연하여 선재를 얻는 단계, 상기 선재를 수냉한 후, 권취하는 단계, 및 상기 권취된 선재를 공냉하는 단계를 포함하고, 상기 선재 압연시, 최종 압연 스탠드에서의 롤의 용적톤수(tonnage)가 200톤 이하(0톤 제외)인 타이어 코드용 선재의 제조방법이 개시된다.

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Номер записи: 13
04-10-2012 дата публикации

NOVEL OXAZOLIDINONE DERIVATIVE AND MEDICAL COMPOSITION CONTAINING SAME

Номер: WO2012134188A3
Автор: CHO, Young Lag, BAEK, Sung Yoon, CHAE, Sang Eun, KIM, Sun Young, LEE, Hong Bum, LEE, Hyang Sook, OH, Kyuman, HEO, Hye Jin, PARK, Tae Kyo, WOO, Sung Ho, KIM, Yong Zu
Принадлежит:

The present invention relates to a novel oxazolidinone derivative indicated as chemical formula 1 on the description, and in particular, to a novel oxazolidinone compound having a cyclic amidoxime or a cyclic amidrazone group. In the chemical formula 1, R and Q are identical to as defined in the detailed explanation. In addition, the present invention relates to an antibiotic medical compound having the novel oxazolidinone derivative of the chemical formula 1, a prodrug thereof, a hydrate thereof, a solvate thereof, an isomer thereof, and a pharmaceutically permitted salt thereof, as active ingredients. The novel oxazolidinone derivative of the present invention, the prodrug thereof, the hydrate thereof, the solvate thereof, the isomer thereof, and the pharmaceutically permitted salt thereof, have a wide antibacterial spectrum for resistant bacteria, have low toxicity, and show strong antibacterial effect on gram positive and gram negative bacteria, and is thereby useful as an antibiotic ...

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Номер записи: 14
04-07-2017 дата публикации

METHOD OF MANUFACTURING WIRE FOR TIRE CORD WITH EXCELLENT MECHANICAL DETACHABILITY

Номер: KR1020170075860A
Автор: HEO, HYE JIN, YANG, YO SEP
Принадлежит:

Disclosed is a method of manufacturing a wire for a tire cord with excellent mechanical detachability, comprising: a step of obtaining a wire by hot-rolling a billet; a step of enabling the wire to be wound after water-cooling the wire; and a step of air-cooling the wound wire. Measurement tonnage of a roll during a final rolling stand is less than or equal to 200 ton (excluding 0 ton) when the wire is rolled. COPYRIGHT KIPO 2017 ...

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Номер записи: 15
11-05-2015 дата публикации

GUANIDINE COMPOUNDS AND USE THEREOF

Номер: KR1020150051016A
Автор: KIM HONG WOO, LEE, JI SUN, HEO, HYE JIN, LEE, HONG BUM, JEONG, JAE KAP, KIM, MI JEONG, KOOK, JI AE, CHO, WOONG
Принадлежит:

The present invention relates to guanidine compounds and use thereof, and more specifically, to a guanidine derivative having an excellent effect on suppressing cancer-cell proliferation, and suppressing cancer metastasis and recurrence, a method for preparing the same, and pharmaceutical compositions containing the same as active ingredients. COPYRIGHT KIPO 2015 ...

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Номер записи: 16
04-10-2012 дата публикации

NOVEL OXAZOLIDINONE DERIVATIVE AND MEDICAL COMPOSITION CONTAINING SAME

Номер: WO2012134188A2
Автор: CHO, Young Lag, BAEK, Sung Yoon, CHAE, Sang Eun, KIM, Sun Young, LEE, Hong Bum, LEE, Hyang Sook, OH, Kyuman, HEO, Hye Jin, PARK, Tae Kyo, WOO, Sung Ho, KIM, Yong Zu
Принадлежит:

The present invention relates to a novel oxazolidinone derivative indicated as chemical formula 1 on the description, and in particular, to a novel oxazolidinone compound having a cyclic amidoxime or a cyclic amidrazone group. In the chemical formula 1, R and Q are identical to as defined in the detailed explanation. In addition, the present invention relates to an antibiotic medical compound having the novel oxazolidinone derivative of the chemical formula 1, a prodrug thereof, a hydrate thereof, a solvate thereof, an isomer thereof, and a pharmaceutically permitted salt thereof, as active ingredients. The novel oxazolidinone derivative of the present invention, the prodrug thereof, the hydrate thereof, the solvate thereof, the isomer thereof, and the pharmaceutically permitted salt thereof, have a wide antibacterial spectrum for resistant bacteria, have low toxicity, and show strong antibacterial effect on gram positive and gram negative bacteria, and is thereby useful as an antibiotic ...

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Номер записи: 17
26-05-2016 дата публикации

BIGUANIDE COMPOUND AND USE THEREOF

Номер: WO2016080810A3
Автор: KIM, Hong Woo, JEONG, Jae Kap, LEE, Ji Sun, HEO, Hye Jin, LEE, Hong Bum, KOOK, Ji Ae, KIM, Sung Wuk
Принадлежит:

The present invention relates to a guanidine compound and a use thereof. More specifically, the present invention relates to a guanidine derivative showing excellent effects in inhibition of cancer cell proliferation, cancer metastasis and cancer recurrence, a preparation method thereof, and a pharmaceutical composition containing the same as an active ingredient. Compared to existing drugs, the guanidine derivative according to the present invention shows excellent effects in inhibition of cancer cell proliferation and cancer metastasis and recurrence even with small doses, and therefore may be effectively used in prevention or treatment of various cancers such as uterine cancer, breast cancer, stomach cancer, brain cancer, rectal cancer, colorectal cancer, lung cancer, skin cancer, blood cancer, liver cancer, etc., inhibition of cancer cell proliferation, and inhibition of cancer metastasis.

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Номер записи: 18
02-09-2016 дата публикации

신규한 옥사졸리디논 유도체 및 이를 함유하는 의약 조성물

Номер: KR0101653570B1
Автор: 조영락, 백성윤, 채상은, 김선영, 이홍범, 이향숙, 오규만, 허혜진, 박태교, 우성호, 김용주
Принадлежит: 주식회사 레고켐 바이오사이언스

... 본 발명은 하기 화학식 1로 표시되는 신규한 옥사졸리디논 유도체, 특히 사이클릭 아미독심 또는 사이클릭 아미드라존 기를 가지는 신규한 옥사졸리디논 화합물에 관한 것이다. (1) 상기 식에서, R 및 Q는 발명의 상세한 설명에 정의된 바와 동일하다. 또한 본 발명은 상기 화학식 1의 신규한 옥사졸리디논 유도체, 이의 프로드럭, 이의 수화물, 이의 용매화물, 이의 이성질체 및 이의 약제학적으로 허용되는 염을 유효성분으로 함유하는 항생제용 의약 조성물에 관한 것이다. 본 발명에 따른 신규한 옥사졸리디논 유도체, 이의 프로드럭, 이의 수화물, 이의 용매화물, 이의 이성질체 및 이의 약제학적으로 허용되는 염은 내성균에 대한 항균 스펙트럼이 넓고, 독성이 낮으며, 그람양성 및 그람음성균에 강한 항균효과를 나타내므로, 항생제로 유용하게 사용될 수 있다.

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Номер записи: 19
14-09-2017 дата публикации

COMPOSITION FOR INDUCING DIFFERENTIATION OF CARDIOMYOCYTE CONTAINING ECHINOCHROME A AS ACTIVE INGREDIENT

Номер: WO2017155129A1
Автор: HAN, Jin, HEO, Hye Jin, KIM, Nari, KIM, Hyoung Kyu
Принадлежит:

The present invention relates to a pharmaceutical composition for promoting differentiation of cardiomyocytes derived from embryonic stem cells containing Echinochrome A as an active ingredient. More specifically, since it has been confirmed that Echinochrome A extracted from Plococidaris verticillata of Echinodermata exhibits non-cytotoxicity and effectively induces differentiation from mouse embryonic stem cells into cardiomyocytes, the composition containing Echinochrome A as an active ingredient according to the present invention may be provided as a composition or a medium composition for inducing differentiation of cardiomyocytes.

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Номер записи: 20
26-05-2016 дата публикации

BIGUANIDE COMPOUND AND USE THEREOF

Номер: WO2016080810A2
Автор: KIM, Hong Woo, JEONG, Jae Kap, LEE, Ji Sun, HEO, Hye Jin, LEE, Hong Bum, KOOK, Ji Ae, KIM, Sung Wuk
Принадлежит:

The present invention relates to a guanidine compound and a use thereof. More specifically, the present invention relates to a guanidine derivative showing excellent effects in inhibition of cancer cell proliferation, cancer metastasis and cancer recurrence, a preparation method thereof, and a pharmaceutical composition containing the same as an active ingredient. Compared to existing drugs, the guanidine derivative according to the present invention shows excellent effects in inhibition of cancer cell proliferation and cancer metastasis and recurrence even with small doses, and therefore may be effectively used in prevention or treatment of various cancers such as uterine cancer, breast cancer, stomach cancer, brain cancer, rectal cancer, colorectal cancer, lung cancer, skin cancer, blood cancer, liver cancer, etc., inhibition of cancer cell proliferation, and inhibition of cancer metastasis.

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Номер записи: 21
20-12-2017 дата публикации

구아니딘 화합물 및 이의 용도

Номер: KR1020170140398A
Автор: 김성욱, 김홍우, 유상희, 이지선, 허혜진, 이홍범, 국지애, 이영우
Принадлежит:

... 본 발명은 미토콘드리아의 산화적 인산화 (OXPHOS)를 억제하기 위한 구아니딘 화합물 및 이의 용도에 관한 것이다. 보다 구체적으로는, 본 발명은 미토콘드리아의 산화적 인산화를 억제하고 세포 대사를 재프로그래밍함으로써 OXPHOS-관련 질환, 특히, 암을 예방 또는 치료하기 위한 약학적 조성물에 관한 것이다.

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Номер записи: 22
22-02-2017 дата публикации

NOVEL IDO-1 INHIBITOR AND USE THEREOF

Номер: KR1020170019814A
Автор: KIM, SUNG WUK, KIM HONG WOO, YOO SANG HEE, HEO, HYE JIN, LEE, HONG BUM, KIM, HYUN WOOK
Принадлежит:

The present invention relates to an IDO-1 inhibitor and uses thereof, and more specifically, to an IDO-1 inhibitor which realizes excellent effects in suppressing cancer metastasis and cancer recurrence by suppressing the action of an enzyme in cell, Indoleamine-2,3-dioxygenase (IDO); to a preparation method thereof; and to a pharmaceutical composition comprising the same as an active ingredient. The IDO-1 inhibitor according to the present invention, even in small amounts, can effectively suppress the enzymatic activity of the IDO enzyme in the cell and show excellent effects in suppressing cancer metastasis and cancer recurrence, and thus can be used beneficially in the treatment of uterus cancer, breast cancer, stomach cancer, rectal cancer, colon cancer, lung cancer, skin cancer, blood cancer, liver cancer, etc. COPYRIGHT KIPO 2017 ...

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Номер записи: 23
30-05-2016 дата публикации

BIGUANIDE COMPOUND AND USE THEREOF

Номер: KR1020160060512A
Автор: KIM, SUNG WUK, KIM HONG WOO, JEONG, JAE KAP, LEE, JI SUN, HEO, HYE JIN, LEE, HONG BUM, KOOK, JI AE
Принадлежит:

The present invention relates to a biguanide compound and a use thereof. More particularly, the present invention relates to biguanide derivative exhibiting excellent efficacy in suppressing cancer cell proliferation, cancer metastasis, and cancer recurrence; a manufacturing method thereof; and a pharmaceutical composition comprising the same as effective component. According to the present invention, biguanide derivative exhibits efficacy in suppressing cancer cell proliferation, cancer metastasis, and cancer recurrence with little dose in comparison to a conventional drug. Therefore, the biguanide derivative can be usefully used to treat various cancers such as uterine cancer, breast cancer, gastric cancer, brain cancer, rectal cancer, lung cancer, skin cancer, blood cancer, liver cancer, etc. Also, the biguanide derivative can be used to suppress proliferation of cancer cells and cancer cell metastasis. COPYRIGHT KIPO 2016 ...

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Номер записи: 24