Apparatus for determing and/or monitoring temperature

An apparatus for determining and/or monitoring temperature, having: at least one housing, which has at least one inner space; and at least one cable duct for inserting at least one cable into an inner space of the housing; wherein the cable duct has at least one cable entrance and one cable exit opening into an inner space of the housing. The cable duct and the inner space of the housing are embodied and matched to one another in such a manner that the cable to be inserted in the cable duct extends essentially tangentially into the inner space of the housing, and is guided essentially radially in the inner space of the housing.

Methods of Manufacturing Semiconductor Devices

Semiconductor devices and methods of manufacture thereof are disclosed. In one embodiment, a semiconductor device includes an array having at least one first region and at least one second region. The first region includes at least one first device oriented in a first direction. The second region includes at least one second device oriented in a second direction. The second direction is different than the first direction. 1. A semiconductor device comprising:an array comprising a first region and a second region, the first region comprising the first device oriented in a first direction, the second region comprising the second device oriented in a second direction, the second direction being different than the first direction, wherein the first region and the second region comprise a cell, wherein the cell comprises one of the first region comprising devices oriented in a +y direction, another one of the first region comprising devices oriented in a −y direction, one of the second region comprising devices oriented in a +x direction, and another one of the second region comprising devices oriented in a −x direction.2. The semiconductor device according to claim 1 , wherein the cell is repeated a plurality of times in the array.3. The semiconductor device according to claim 1 , wherein the second direction is substantially perpendicular to the first direction.4. The semiconductor device according to claim 1 , wherein the first device in the first region and the second device in the second region are coupled together in parallel.5. The semiconductor device according to claim 1 , wherein the first device and the second device comprise a gate contact comprising a length claim 1 , the gate contact being disposed over a junction between a first well and a second well over substantially the entire length of the gate contact.6. The semiconductor device according to claim 5 , wherein the length of the gate contact of the first device in the first region extends in the first ...

Fixture for spatial positioning of a device

In a fixture for spatial positioning of a device, in particular a device for a medical application, that is supported in a pivoting arrangement on a holding device or the like by means of an arm, quick and easy alignment of the device in relation to a person's treatment area is provided. This alignment is achieved in that a ring-shaped holding body is attached to the free end of the arm, that a spherical outer jacket surface is provided on the device with the surface enclosed wholly or in part by the holding body, and that the outer jacket surface of the device is held in the holding body and can be pivoted relative to the holding body.

Method for the preparation of halogenated benzonitriles

The present invention relates to a method for preparing halogenated benzonitriles by vapor phase ammoxidation at a reaction temperature in the range of 300 to 500° C. in a fixed bed reactor using a three-component catalyst. More particularly, the method of the invention relates to a method for preparing 2,6-dichlorobenzonitrile (2,6-DCBN) from 2,6-dichlorotoluene (2,6-DCT) by vapor phase ammoxidation. The invention also relates to a three-component catalyst provided on a carrier and its use in a vapor phase ammoxidation reaction according to the invention. In addition, the invention provides a method for preparing the three-component catalyst.

Process for the production of 17-oxabicyclo[14.1.0]heptadec-8-ene

The invention relates to a process for producing 17-oxabicyclo[14.1.0]heptadec-8-ene comprising a reaction with the reactants cyclohexadeca-1,9-diene and hydrogen peroxide.

Dielectric Film and Layer Testing

A system for testing and a method for making a semiconductor device is disclosed. A preferred embodiment includes a conductor overlying a dielectric layer. The conductor is coupled to a first test pad via a first conducting line and to a second test pad via a second conducting line.

DEVICE FOR DETACHING AT LEAST ONE BURR FROM AN OPENING OF AT LEAST ONE TRANSVERSE BORE-HOLE OF A WORKPIECE, DRILLING STATION HAVING THE DEVICE AND METHOD FOR DETACHING THE AT LEAST ONE BURR USING THE DRILLING STATION

A device for detaching a burr from an opening of a transverse borehole of a workpiece includes an elongate shank for positioning in a longitudinal borehole of the workpiece and a fillet to avoid the elongate shank colliding with a drill for drilling the transverse borehole. In an example embodiment, the device has an aperture to further avoid the elongate shank colliding with the drill. In an example embodiment, the elongate shank has a cutting section with a cutting edge for detaching the burr from the opening of the transverse borehole.

Video-on-demand system

A video-on-demand system including a video server storing video-on-demand content and for streaming video-on-demand through a first layer of an internet page having a first layer and a second layer; and a controller for causing there to be formed in the second layer a plurality of selectable overlay images such that a user at a location in communication with the internet remote from the video server and the controller can display streamed video-on-demand of the first layer in combination with the overlay images of the second layer and can select one of the overlay images; wherein the overlay images correspond to respective control functions for the video-on-demand stream; and the controller is responsive to selection of an overlay image to change the video-on-demand stream in accordance with the corresponding respective control function.

Method for detecting the reliability of integrated semiconductor components at high temperatures

The invention relates to a device and a method for detecting the reliability of integrated semiconductor components. The device includes a carrier substrate for receiving an integrated semiconductor component that will be examined, a heating element, and a temperature sensor. The temperature sensor has at least a portion of a parasitic functional element of the semiconductor component. As a result, reliability tests can be carried out in a particularly accurate and space-saving manner.

Method For Producing 1,2-Pentanediol

A process for the preparation of 1,2-pentanediol by reaction of a starting material comprising one or both compounds from the group consisting of furfuryl alcohol and furfural with hydrogen in the presence of a first heterogeneous catalyst is described. 1. A process for the preparation of 1 ,2-pentanediol comprising reacting a starting material comprising one or both compounds selected from the group consisting of furfuryl alcohol and furfural with hydrogen in the presence of a first heterogeneous catalyst to form a mixture comprising 1 ,2-pentanediol and optionally one or more compounds selected from the group consisting of 1-hydroxy-2-pentanone , furfuryl alcohol and furfural , one or more metals selected from the group consisting of platinum, rhodium, ruthenium, nickel, palladium and iridium in metallic form and/or one or more compounds of metals selected from the group consisting of platinum, rhodium, ruthenium, nickel, palladium and iridium; and', 'one or more support materials., 'wherein the first heterogeneous catalyst comprises2. The process according to claim 1 , wherein the first heterogeneous catalyst comprises platinum in metallic form and/or one or more platinum (IV) compounds.3. The process according to claim 1 , wherein in the first heterogeneous catalyst claim 1 , the total concentration of the one or more metals and/or one or more compounds of metals is in the range from 0.1 wt. % to 50 wt. % based on the total weight of all the constituents of the first heterogeneous catalyst.4. The process according to claim 1 , wherein in the reaction in the presence of the first heterogeneous catalyst the hydrogen partial pressure is in the range from 1 bar to 20 bar.5. The process according to claim 1 , wherein in the reaction in the presence of the first heterogeneous catalyst the molar ratio between hydrogen and the total amount of furfuryl alcohol and furfural is 1:1 or more.6. The process according to claim 1 , wherein the reaction in the presence of the ...

DIRECT HYDROXYLATION OF BENZENE TO PHENOL

The invention provides a method for preparing phenols from aromatic compounds, particularly a method of preparing phenol by direct hydroxylation of benzene. The method comprises contacting benzene with nitrous oxide in the presence of a bimetallic zeolite catalyst at an ambient pressure and a reaction temperature ranging from (about) 320° C. to 440° C. 1. A method for direct hydroxylation of aromatic compounds to produce phenols , comprising contacting the aromatic compounds with nitrous oxide in presence of a bimetallic zeolite catalyst including V—Ti bimetallic ions at an ambient pressure and a reaction temperature ranging from 320° C. to 440° C. wherein the bimetallic zeolite catalyst including V—Ti bimetallic ions is selected from a group consisting of V—Ti/ZSM-5 , V—Ti/Ga-ZSM-5 , V—Ti/BEA or V—Ti/USY.2. A method for direct hydroxylation of aromatic compounds to produce phenols , comprising contacting benzene with nitrous oxide in presence of a bimetallic zeolite catalyst including V—Ti bimetallic ions , wherein the bimetallic zeolite catalyst including V—Ti bimetallic ions is selected from a group consisting of V—Ti/ZSM-5 , V—Ti/Ga-ZSM-5 , V—Ti/BEA or V—Ti/USY.3. The method according to claim 2 , wherein the mixture of benzene and nitrous oxide is diluted with nitrogen gas.4. The method according to claim 3 , wherein the molar ratio of C6H6:N2O:N2 is 1:1.5:82.3.5. (canceled)6. The method according to claim 1 , wherein contacting of aromatic compounds with nitrous oxide occurs at a contact time of 1 second.7. The method according to claim 1 , wherein the conversion of benzene to phenol is in the range of 20 mol percent to 27 mol percent. The invention generally relates to a method for preparing phenols from aromatic compounds. More specifically, the invention relates to a method for preparing phenol from benzene by a direct hydroxylation process in the presence of a catalyst.A number of multi-step as well as the more recent single-step processes for producing ...

Washing device

In a washing element holder (2), which on one side is closed off relative to the outside (s) with a sponge material (5) having pores (4), a washing device (1) has a washing element (3) which has at least one synthetic surfactant as a foaming substance and the principal constituent.

Washing device

In a washing element holder (2), which on one side is closed off relative to the outside(s) with a sponge material (5) having pores (4), a washing device (1) has a washing element (3) which has at least one synthetic surfactant as a foaming substance and the principal constituent.

Internal combustion engine and method for the operation thereof

The combustion engine has two rotary pistons (2,3) mounted rotatable in a housing (4) and each having a cylindrical core and outer ring whose radius corresponds in areas to the inner radius of the housing and whose thickness corresponds in areas to the thickness of the core. In the outer ring is a segment with smaller radius and/or different thickness so that a combustion chamber is defined between each housing and piston and the combustion chambers are connectable together. They can be sealed from each other at least in areas through at least one slider (5,6) which can be moved by the rotary piston.

PROCESS FOR THE PRODUCTION OF 17-Oxabicyclo[14.1.0]heptadec-8-ene

The invention relates to a process for producing 17-oxabicyclo[14.1.0]heptadec-8-ene comprising a reaction with the reactants cyclohexadeca-1,9-diene and hydrogen peroxide. 1. Process for producing 17-oxabicyclo[14.1.0]heptadec-8-ene comprising a reaction with the reactants , cyclohexadeca-1 ,9-diene and hydrogen peroxide.2. Process according to claim 1 , characterized in that the reaction is carried out in a two-phase system.3. Process according to or claim 1 , characterized in that the reaction is carried out in the presence of a catalyst.4. Process according to one of the foregoing claims claim 1 , characterized in that the catalyst contains phosphorus.5. Process according to one of the foregoing claims claim 1 , characterized in that the catalyst contains tungsten.6. Process according to one of the foregoing claims claim 1 , characterized in that the active species of the catalyst contains a peroxotungstophosphate.7. Process according to one of the foregoing claims claim 1 , characterized in that the active species of the catalyst contains the anion claim 1 , {PO[WO(O)]}.8. Process according to one of the foregoing claims claim 1 , characterized in that the active species of the catalyst contains a cation of a phase transfer catalyst—preferably claim 1 , a tetraalkylammonium cation.10. Process according to one of the foregoing claims claim 1 , characterized in that the active species of the catalyst is formed from at least one phosphorus-containing acid claim 1 , at least one tungsten (VI)-compound claim 1 , and at least one phase transfer catalyst—preferably claim 1 , in situ.11. Process according to claim 10 , characterized in that the phosphorus-containing acid is selected from phosphoric acid claim 10 , phosphonic acids claim 10 , phosphinic acids claim 10 , and heteropoly acids and their derivatives claim 10 ,the tungsten (VI)-compound is selected from alkali tungstates, alkaline-earth tungstates, ammonium tungstates, or tungsten trioxide monohydrate— ...

Methods of manufacturing semiconductor devices

Semiconductor devices and methods of manufacture thereof are disclosed. In one embodiment, a semiconductor device includes an array having at least one first region and at least one second region. The at least one first region includes at least one first device oriented in a first direction. The at least one second region includes at least one second device oriented in a second direction. The second direction is different than the first direction.

Semiconductor device, semiconductor test structure and method for fabricating a semiconductor device

An insulation region comprising a dielectric is applied to an electrically active region, and then an electrically conductive region which is connected to an electrically conductive supply conductor is applied to the insulation region. An auxiliary conductor track, which is connected to a region which is highly doped at least with doping atoms of a first conductivity type, is arranged adjacent to the electrically conductive supply conductor.

Semiconductor discharge devices and methods of formation thereof

In one embodiment, a method of forming a semiconductor device includes forming a well region within a substrate. A plurality of transistors is formed within and/or over the well region. The method further includes forming a first discharge device within the substrate. The first discharge device is coupled to the well region and a low voltage node. During subsequent processing, the first discharge device discharges charge from the well region.

Semiconductor devices having transistors along different orientations

Semiconductor devices and methods of manufacture thereof are disclosed. In one embodiment, a semiconductor device includes an array having at least one first region and at least one second region. The at least one first region includes at least one first device oriented in a first direction. The at least one second region includes at least one second device oriented in a second direction. The second direction is different than the first direction.

Video-on-demand system

A video-on-demand system including a video server storing video-on-demand content and for streaming video-on-demand through a first layer of an internet page having a first layer and a second layer; and a controller for causing there to be formed in the second layer a plurality of selectable overlay images such that a user at a location in communication with the internet remote from the video server and the controller can display streamed video-on-demand of the first layer in combination with the overlay images of the second layer and can select one of the overlay images; wherein the overlay images correspond to respective control functions for the video-on-demand stream; and the controller is responsive to selection of an overlay image to change the video-on-demand stream in accordance with the corresponding respective control function.

Dielectric Film and Layer Testing

A system for testing and a method for making a semiconductor device is disclosed. A preferred embodiment includes a conductor overlying a dielectric layer. The conductor is coupled to a first test pad via a first conducting line and to a second test pad via a second conducting line.

Process for preparing linear alpha,omega-dicarboxylic diesters

The invention provides a process for preparing linear alpha,omega-dicarboxylic diesters by reacting a triglyceride containing fatty acid residues having monounsaturated or polyunsaturated carbon chains with carbon monoxide, an acid and an OH-group donor in one reaction step in the presence of a catalyst.

Video-on-demand system

A video-on-demand system including a video server storing video-on-demand content and for streaming video-on-demand through a first layer of an internet page having a first layer and a second layer; and a controller for causing there to be formed in the second layer a plurality of selectable overlay images such that a user at a location in communication with the internet remote from the video server and the controller can display streamed video-on-demand of the first layer in combination with the overlay images of the second layer and can select one of the overlay images; wherein the overlay images correspond to respective control functions for the video-on-demand stream; and the controller is responsive to selection of an overlay image to change the video-on-demand stream in accordance with the corresponding respective control function.

Semiconductor Discharge Devices and Methods of Formation Thereof

In one embodiment, a method of forming a semiconductor device includes forming a well region within a substrate. A plurality of transistors is formed within and/or over the well region. The method further includes forming a first discharge device within the substrate. The first discharge device is coupled to the well region and a low voltage node. During subsequent processing, the first discharge device discharges charge from the well region.

PROCESS FOR HOMOGENEOUSLY CATALYZED, HIGHLY SELECTIVE DIRECT AMINATION OF PRIMARY ALCOHOLS WITH AMMONIA TO PRIMARY AMINES WITH A HIGH VOLUME RATIO OF LIQUID PHASE TO GAS PHASE AND/OR HIGH PRESSURES

The present invention relates to a process for preparing primary amines comprising the process steps 1. A process for preparing a primary amine , the process comprisingA)contacting (i) a solution of a primary alcohol in a fluid, nongaseous phase with (ii) free ammonia or an ammonia-releasing compound and (iii) a homogeneous catalyst, to form a primary amine, and optionallyB) isolating the primary aminewherein a volume ratio of a volume of a liquid phase to a volume of a gas phase in the contacting is greater than 0.05 and/orthe contacting is performed at a pressure greater than 10 bar.2. The process of claim 1 , wherein in the contactingthe ammonia is present in a molar ratio based on hydroxyl groups in the primary alcohol of at least 5:1.3. The process of claim 1 , whereinthe primary alcohol comprises a carboxyl or ester group.4. The process of claim 1 , whereinthe primary alcohol comprises an aliphatic alkyl radical comprising at least three carbon atoms covalently bound to one another and no quaternary carbon atom.5. The process of claim 1 , whereinthe primary alcohol comprises no heteroatoms.6. The process of claim 4 , whereinthe aliphatic alkyl radical is a linear or branched alkyl radical comprising at least 4 carbon atoms.7. The process of claim 1 , whereinthe primary alcohol is selected from the group consisting of 1-butanol, 2-methyl-1-propanol, 1-pentanol, 3-methyl-1-butanol, 2-methyl-1-butanol, 1-hexanol, 4-methyl-1-pentanol, 3-methyl-1-pentanol, 2-methyl-1-pentanol, 2-ethyl-1-butanol, tripropylene glycol, an anhydrohexitol, and tripropylene glycol.8. The process of claim 1 , whereina concentration of the primary alcohol in (i) is from 0.1 to 10000 mmol/l.9. The process of claim 1 , whereinthe catalyst is selected from the group consisting of:an alkali metal alkoxide, an aluminum alkoxide, a lanthanide alkoxide,an inorganic compound comprising a noble metal,and a coordination compound comprising one or more noble metals selected from the group consisting ...

Process for brominating alkylthiophenes

What is described is a process for brominating alkylthiophene, in which an alkylthiophene of the general formula (I) where R is a branched or unbranched alkyl radical having 1 to 12 carbon atoms is contacted with stoichiometric amounts of HBr and H2O2, optionally in the presence of a solvent.

Semiconductor Devices and Methods for Testing a Gate Insulation of a Transistor Structure

A semiconductor device includes a first test structure including a first portion of a conductive structure and a second portion of the conductive structure located within a first lateral wiring layer of a layer stack of the semiconductor device. The first portion of the conductive structure of the first test structure is electrically connected to the second portion of the conductive structure of the first test structure through a third portion located within a second lateral wiring layer of the layer stack arranged above the first lateral wiring layer. Further, the first portion of the conductive structure of the first test structure is electrically connected to a gate of a test transistor structure, a doping region of the test transistor structure or an electrode of a test capacitor. Additionally, the first portion of the conductive structure of the first test structure is electrically connected to a first test pad of the first test structure. 1. A semiconductor device comprising a first test structure , wherein:the first test structure comprises a first portion of a conductive structure and a second portion of the conductive structure located within a first lateral wiring layer of a layer stack of the semiconductor device;the first portion of the conductive structure of the first test structure is electrically connected to the second portion of the conductive structure of the first test structure through a third portion located within a second lateral wiring layer of the layer stack arranged above the first lateral wiring layer;the first portion of the conductive structure of the first test structure is electrically connected to a gate of a test transistor structure, a doping region of the test transistor structure or an electrode of a test capacitor;the first portion of the conductive structure of the first test structure is electrically connected to a first test pad of the first test structure; anda sum of a lateral area occupied by the first portion of the ...

Preparation of primary diamines having a linear main chain for polyamide syntheses

The invention provides a method to produce primary diamines by catalytic conversion of diols having a linear main chain of from 4 to 31 carbon atoms into the corresponding diamines. The reaction is conducted in a liquid or supercritical phase and is catalyzed by a homogeneous ruthenium-containing complex. The primary diamines obtained may be suitable for polyamide syntheses.

VIDEO-ON-DEMAND SYSTEM

A video-on-demand system including a video server storing video-on-demand content and for streaming video-on-demand through a first layer of an internet page having a first layer and a second layer; and a controller for causing there to be formed in the second layer a plurality of selectable overlay images such that a user at a location in communication with the internet remote from the video server and the controller can display streamed video-on-demand of the first layer in combination with the overlay images of the second layer and can select one of the overlay images; wherein the overlay images correspond to respective control functions for the video-on-demand stream; and the controller is responsive to selection of an overlay image to change the video-on-demand stream in accordance with the corresponding respective control function. 126-. (canceled)27. A video-on-demand system accessible over the internet , the system comprising:a video server storing video-on-demand content and for streaming video-on-demand through a first layer of an internet page having a first layer and a second layer; anda controller for causing there to be formed in the second layer a plurality of selectable overlay images such that a user at a location in communication with the internet remote from the video server and the controller can display streamed video-on-demand of the first layer in combination with the overlay images of the second layer and can select one of the overlay images; whereinthe overlay images correspond to respective control functions for the video-on-demand stream; andthe controller is responsive to selection of an overlay image to change the video-on-demand stream in accordance with the corresponding respective control function.28. A video-on-demand system according to claim 27 , wherein the controller is arranged to provide the overlay images in the internet page in a form for storage by the user in a cache and to control display of the overlay images in ...

DIELECTRIC FILM AND LAYER TESTING

A system for testing and a method for making a semiconductor device is disclosed. A preferred embodiment includes a conductor overlying a dielectric layer. The conductor is coupled to a first test pad via a first conducting line and to a second test pad via a second conducting line.

Electromigration test structure for detecting the reliability of wiring

An electromigration test structure detects the reliability of wirings. A region to be tested has an electromigration region and an electromigration barrier region formed between first and second test structure terminal regions. In order to estimate a service life in a manner that is highly accurate and suitable for highly accelerated tests, a first and third sensor terminal are situated in direct proximity to the electromigration barrier region, and a second sensor terminal is situated at the second test structure terminal region.

Semiconductor Devices and Methods of Manufacture Thereof

Semiconductor devices and methods of manufacture thereof are disclosed. In one embodiment, a semiconductor device includes an array having at least one first region and at least one second region. The at least one first region includes at least one first device oriented in a first direction. The at least one second region includes at least one second device oriented in a second direction. The second direction is different than the first direction.

Method for preparation of dicarboxylic acids from saturated hydrocarbons or cycloaliphatic hydrocarbons by catalytic oxidation

The present invention relates to a method for preparing dicarboxylic acids from saturated and cycloaliphatic hydrocarbons by oxidation at a reaction temperature comprised in the range of 25 to 300° C. in an autoclave using a solid heterogeneous catalyst. More particularly, the method of the invention relates to a method for preparing adipic acid (AA) from cyclohexane (CH) by selective oxidation.

Method, and storage medium and also device for carrying out same

A method for the computer-aided characterization of a circuit comprising a semiconductor layer and a semiconductor component region embedded in the semiconductor layer in an electrically insulated manner, wherein the semiconductor component region is optionally coupled to a dielectric layer structure to be protected, the method comprising determining an indication representing vis-à-vis the semiconductor layer an intensity of an electrical charging of the semiconductor component region by a production process used to produce the circuit, wherein a physical construction of the semiconductor component region is taken into account when determining the indication, and classifying the semiconductor component region taking account of the indication.

Process for preparing cyanopyridines and suitable catalysts therefor

The invention relates to a method for the manufacture of cyanopyridines from methylpyridines by their conversion with ammonia and oxygen and catalysts suitable therefor which contain further transition metals in addition to vanadium and phosphorus.

Dielectric film and layer testing

A system for testing and a method for making a semiconductor device is disclosed. A preferred embodiment includes a conductor overlying a dielectric layer. The conductor is coupled to a first test pad via a first conducting line and to a second test pad via a second conducting line.

METHOD FOR THE PRODUCTION OF AROMATIC CARBONYL COMPOUNDS

The invention relates to a method for the production of an aromatic carbonyl compound by the oxidation of a methyl group or methylene group bonded to the aromatic group in which the aromatic substance is reacted in the presence of an oxidising agent and a sulphoxide, a sulphoxide being selected for the oxidation of a specific aromatic substance whose ionisation potential, in terms of magnitude, differs from the ionisation potential of the aromatic substance to be oxidised by a maximum of ±0.25 eV.

Device for Determining and/or Monitoring a Process Variable

An apparatus for determining and/or monitoring at least one process variable. The apparatus comprises at least one housing, which has at least a housing lower part and a housing lid. The housing lower part and the housing lid are connected together by at least one connecting element.

Device and method for detecting a reliability of integrated semiconductor components at high temperatures

The invention relates to a device and a method for detecting the reliability of integrated semiconductor components. The device includes a carrier substrate for receiving an integrated semiconductor component that will be examined, a heating element, and a temperature sensor. The temperature sensor has at least a portion of a parasitic functional element of the semiconductor component. As a result, reliability tests can be carried out in a particularly accurate and space-saving manner.

WASHING DEVICE

In a washing element holder (), which on one side is closed off relative to the outside (s) with a sponge material () having pores (), a washing device () has a washing element () which has at least one synthetic surfactant as a foaming substance and the principal constituent. 1. A washing device comprising:a washing element holder at least partially closed to an outside;a sponge material comprising pores; anda washing element inserted into the washing element holder, wherein on at least one side the washing element holder is closed off relative to the outside and the washing element contains at least one synthetic surfactant as a foaming substance and as a principal constituent thereof.2. A washing device in accordance with claim 1 , wherein at least 50% of the washing element consists of the at least one surfactant.3. A washing device in accordance with claim 1 , wherein the washing element is soap-free or is a syndet or is both soap-free and is a syndet.4. A washing device in accordance with claim 1 , wherein the washing element is in a form of a combar or the washing element comprises at least one synthetic surfactant and a soap portion with a soap.5. A washing device in accordance with claim 1 , wherein at least 50% of the washing element comprises the at least one surfactant.6. A washing device comprising:a washing element holder at least partially closed to an outside, the washing element holder comprising a sponge material, the sponge material comprising pores; anda washing element inserted into the washing element holder, wherein on at least one side the washing element holder is closed off relative to the outside with the sponge material and the washing element contains at least one synthetic surfactant as a foaming substance and as the principal constituent thereof, wherein the washing element produces foam without friction being required.7. A washing device in accordance with claim 6 , wherein the washing element is soap-free or is a syndet.8. A washing ...

FIXTURE FOR SPATIAL POSITIONING OF A DEVICE

In a fixture (1) for spatial positioning of a device (2), in particular a device for medical application, that is supported in a pivoting arrangement on a holding device (5) or the like by means of an arm (6), quick and easy alignment of the device (2) in relation to a person's treatment area should be guaranteed. This is achieved in that a ring-shaped holding body (11) is attached to the free end of the arm (6), that a spherical cup-shaped outer jacket surface (13) is provided on the device (2) with the surface enclosed wholly or in part by the holding body (11) and that the outer jacket surface (13) of the device (2) is held in the holding body (11) and can be pivoted relative to the holding body (11).

Semiconductor Devices and Methods of Manufacture Thereof

Semiconductor devices and methods of manufacture thereof are disclosed. In one embodiment, a semiconductor device includes an array having at least one first region and at least one second region. The at least one first region includes at least one first device oriented in a first direction. The at least one second region includes at least one second device oriented in a second direction. The second direction is different than the first direction. 1. A semiconductor device , comprising:an array, the array comprising at least one first region and at least one second region, the at least one first region comprising at least one first device oriented in a first direction, the at least one second region comprising at least one second device oriented in a second direction, the second direction being different than the first direction, wherein the at least one first region and the at least one second region comprise a cell, wherein the cell comprises one of the first region comprising devices oriented in a +y direction, another one of the first region comprising devices oriented in a −y direction, one of the second region comprising devices oriented in a +x direction, and another one of the second region comprising devices oriented in a -x direction.2. The semiconductor device according to claim 1 , wherein the cell is repeated a plurality of times in the array.3. The semiconductor device according to claim 1 , wherein the second direction is substantially perpendicular to the first direction.4. The semiconductor device according to claim 1 , wherein the at least one first device in the at least one first region and the at least one second device in the at least one second region are coupled together in parallel.5. The semiconductor device according to claim 1 , wherein the at least one first device and the at least one second device comprise a gate contact comprising a length claim 1 , the gate contact being disposed over a junction between a first well and a second well ...

Dielectric film and layer testing

A system for testing and a method for making a semiconductor device is disclosed. A preferred embodiment includes a conductor overlying a dielectric layer. The conductor is coupled to a first test pad via a first conducting line and to a second test pad via a second conducting line.

Dielectric film and layer testing

A system for testing and a method for making a semiconductor device is disclosed. A preferred embodiment includes a conductor overlying a dielectric layer. The conductor is coupled to a first test pad via a first conducting line and to a second test pad via a second conducting line.

Method for the preparation of halogenated benzonitriles

The present invention relates to a method for preparing halogenated benzonitriles by vapor phase ammoxidation at a reaction temperature in the range of 300 to 500° C. in a fixed bed reactor using a three-component catalyst. More particularly, the method of the invention relates to a method for preparing 2,6-dichlorobenzonitrile (2,6-DCBN) from 2,6-dichlorotoluene (2,6-DCT) by vapor phase ammoxidation. The invention also relates to a three-component catalyst provided on a carrier and its use in a vapor phase ammoxidation reaction according to the invention. In addition, the invention provides a method for preparing the three-component catalyst.

Method for producing 1,2-pentanediol

A process for the preparation of 1,2-pentanediol by reaction of a starting material comprising one or both compounds from the group consisting of furfuryl alcohol and furfural with hydrogen in the presence of a first heterogeneous catalyst is described.

Method for detecting the reliability of integrated semiconductor components at high temperatures

The invention relates to a device and a method for detecting the reliability of integrated semiconductor components. The device includes a carrier substrate for receiving an integrated semiconductor component that will be examined, a heating element, and a temperature sensor. The temperature sensor has at least a portion of a parasitic functional element of the semiconductor component. As a result, reliability tests can be carried out in a particularly accurate and space-saving manner.

Video-on-demand system

A video-on-demand system including a video server storing video-on-demand content and for streaming video-on-demand through a first layer of an internet page having a first layer and a second layer; and a controller for causing there to be formed in the second layer a plurality of selectable overlay images such that a user at a location in communication with the internet remote from the video server and the controller can display streamed video-on-demand of the first layer in combination with the overlay images of the second layer and can select one of the overlay images; wherein the overlay images correspond to respective control functions for the video-on-demand stream; and the controller is responsive to selection of an overlay image to change the video-on-demand stream in accordance with the corresponding respective control function.

ELECTROMAGNETIC ACTUATOR

Electromagnetic actuator having an armature unit which is axially guided in a housing and movable by passing current through a coil device and in particular against a return force of a return spring out of a first stop position defined by means for limiting the stroke, the means for limiting the stroke having a stop element which is mounted terminally in the housing and manufactured by a shaping, stamping, sintering and/or injection moulding method, and which is designed to cooperate with a plunger unit which can be actuated outside the housing and is designed for mechanically moving the armature out of the first stop position.

Method, and Storage Medium and Also Device for Carrying Out Same

A method for the computer-aided characterization of a circuit comprising a semiconductor layer and a semiconductor component region embedded in the semiconductor layer in an electrically insulated manner, wherein the semiconductor component region is optionally coupled to a dielectric layer structure to be protected, the method comprising determining an indication representing vis-à-vis the semiconductor layer an intensity of an electrical charging of the semiconductor component region by a production process used to produce the circuit, wherein a physical construction of the semiconductor component region is taken into account when determining the indication, and classifying the semiconductor component region taking account of the indication. 1. A method for computer-aided characterization of a circuit comprising a semiconductor layer and a semiconductor component region embedded in the semiconductor layer in an electrically insulated manner , the method comprising:determining an indication representing an intensity of an electrical charging of the semiconductor component region by a production process used to produce the circuit with respect to the semiconductor layer, wherein a physical construction of the semiconductor component region is taken into account when determining the indication; andclassifying the semiconductor component region taking account of the indication.2. The method as claimed in claim 1 ,wherein a spatial surface area of the semiconductor component region is taken into account when determining the indication.3. The method as claimed in claim 1 ,wherein determining the indication comprises taking account of whether the semiconductor component region comprises a semiconductor junction.4. The method as claimed in claim 1 ,wherein the classifying comprises taking account of whether the semiconductor component region adjoins a dielectric layer structure to be protected.5. The method as claimed in claim 1 ,wherein the classifying comprises taking ...

Process for homogeneously catalyzed, highly selective direct amination of primary alcohols with ammonia to primary amines with a high volume ratio of liquid phase to gas phase and/or high pressures

The present invention relates to a process for preparing primary amines comprising the process steps A) provision of a solution of a primary alcohol in a fluid, nongaseous phase, B) contacting of the phase with free ammonia and/or at least one ammonia-releasing compound and a homogeneous catalyst and optionally C) isolation of the primary amine formed in process step B), characterized in that the volume ratio of the volume of the liquid phase to the volume of the gas phase in process step B is greater than 0.05 and/or in that process step B is carried out at pressures greater than 10 bar.

Electromagnetic actuator

Electromagnetic actuator having an armature unit which is axially guided in a housing and movable by passing current through a coil device and in particular against a return force of a return spring out of a first stop position defined by means for limiting the stroke, the means for limiting the stroke having a stop element which is mounted terminally in the housing and manufactured by a shaping, stamping, sintering and/or injection molding method, and which is designed to cooperate with a plunger unit which can be actuated outside the housing and is designed for mechanically moving the armature out of the first stop position.

Semiconductor devices and methods for testing a gate insulation of a transistor structure

A semiconductor device includes a first test structure including a first portion of a conductive structure and a second portion of the conductive structure located within a first lateral wiring layer of a layer stack of the semiconductor device. The first portion of the conductive structure of the first test structure is electrically connected to the second portion of the conductive structure of the first test structure through a third portion located within a second lateral wiring layer of the layer stack arranged above the first lateral wiring layer. Further, the first portion of the conductive structure of the first test structure is electrically connected to a gate of a test transistor structure, a doping region of the test transistor structure or an electrode of a test capacitor. Additionally, the first portion of the conductive structure of the first test structure is electrically connected to a first test pad of the first test structure.

PROCESS FOR PREPARING LINEAR ALPHA,OMEGA-DICARBOXYLIC DIESTERS

The invention provides a process for preparing linear alpha,omega-dicarboxylic diesters by reacting a triglyceride containing fatty acid residues having monounsaturated or polyunsaturated carbon chains with carbon monoxide, an acid and an OH-group donor in one reaction step in the presence of a catalyst.

VIDEO-ON-DEMAND SYSTEM

A video-on-demand system including a video server storing video-on-demand content and for streaming video-on-demand through a first layer of an internet page having a first layer and a second layer; and a controller for causing there to be formed in the second layer a plurality of selectable overlay images such that a user at a location in communication with the internet remote from the video server and the controller can display streamed video-on-demand of the first layer in combination with the overlay images of the second layer and can select one of the overlay images; wherein the overlay images correspond to respective control functions for the video-on-demand stream; and the controller is responsive to selection of an overlay image to change the video-on-demand stream in accordance with the corresponding respective control function. 1. (canceled)2. A electronic device comprising:an interface configured to receive video-on-demand content via a network;a processor configured to decode an internet page via which the video-on-demand content is received, the internet page including the first layer and a second layer, the second layer including a plurality of selectable overlay images,wherein the processor is further configured to output for display received video-on-demand content in the first layer in combination with the overlay images of the second layer and is configured to allow selection of one of the overlay images,the overlay images correspond to respective control functions for the video-on-demand content, andthe processor is responsive to selection of an overlay image to change the video-on-demand content in accordance with the corresponding control function.3. The electronic device according to claim 2 , wherein the processor is configured to decode the overlay images in the internet page into a form for storage in memory and to output for display the overlay images in combination with the video-on-demand content.4. The electronic device according to ...

PROCESS FOR THE DIRECT AMINATION OF SECONDARY ALCOHOLS WITH AMMONIA TO GIVE PRIMARY AMINES

The invention relates to a process for preparing primary amines which comprises the process steps 1. A process for preparing a primary amine , the process comprising:i) providing a solution of a secondary alcohol in a fluid, nongaseous phase, free ammonia, at least one ammonia-releasing compound, or both,', 'and a homogeneous catalyst, and, 'ii) contacting the solution with'} 'wherein:', 'iii) optionally isolating the primary amine obtained in said contacting ii),'}a) a volume ratio of a liquid phase to a gas phase in said contacting ii) is greater than or equal to 0.25, orb) a molar ratio of the ammonia to hydroxyl groups in the secondary alcohol is at least 5:1, orboth a) and b).2. The process according to claim 1 , wherein the homogeneous catalyst isan alkali metal alkoxide, an aluminium alkoxide, a lanthanide alkoxide, an inorganic compound of noble metals,a monometallic or multimetallic, mononuclear or multinuclear coordination compound of at least one noble metal selected from the group consisting of ruthenium, iridium, rhodium, osmium, palladium, platinum and iron,or any mixture thereof.3. The process according to claim 1 ,whereinthe secondary alcohol comprises at least two secondary hydroxy groups.4. The process according to claim 1 ,whereinthe secondary alcohol comprises a cyclic or polycyclic carbon skeleton.5. The process according to claim 1 ,whereinthe secondary alcohol is selected from the group consisting of:2-dodecanol, cyclododecanol, 4-phenyl-2-butanol, isosorbide, isomannide, isoidite, polypropylene glycol, mannitol, sorbitol, galactitol and an alkyl glycoside.6. The process according to claim 1 ,whereinthe secondary alcohol is selected from the group consisting of an alpha-hydroxycarboxylic acid and an OH-modified, natural fatty acid.7. The process according to claim 1 ,wherein a liquid or supercritical ammonia, a solution of ammonium salts in a solvent, or both is used in said contacting ii).8. The process according to claim 1 ,whereinsaid ...

Process for the direct amination of secondary alcohols with ammonia to give primary amines

The invention relates to a process for preparing primary amines which comprises the process steps A) provision of a solution of a secondary alcohol in a fluid, nongaseous phase, B) contacting of the phase with free ammonia and/or at least one ammonia-releasing compound and a homogeneous catalyst and optionally C) isolation of the primary amine formed in process step B), characterized in that the volume ratio of the volume of the liquid phase to the volume of the gas phase in process step B is greater than or equal to 0.25, and/or in that the ammonia is used in process step B) in a molar ratio based on the hydroxyl groups in the secondary alcohol of at least 5:1.

Method for the production of aromatic carbonyl compounds

The invention relates to a method for the production of an aromatic carbonyl compound by the oxidation of a methyl group or methylene group bonded to the aromatic group in which the aromatic substance is reacted in the presence of an oxidizing agent and a sulphoxide, a sulphoxide being selected for the oxidation of a specific aromatic substance whose ionization potential, in terms of magnitude, differs from the ionization potential of the aromatic substance to be oxidized by a maximum of ±0.25 eV.

Method for synthesising an unsaturated macrocyclic ketone

A method for producing unsaturated macrocyclic monoketones comprising the following steps: (a) preparing macrocyclic dienes with a ring size of at least 9 carbon atoms; (b) contacting the starting materials from step (a) with (b1) a palladium(II) salt and/or a palladium(II) complex; and (b2) an oxidant; and (b3) a solvent; and optionally (b4) a ligand; and optionally (b5) a co-catalyst; and optionally (b6) an acid.

PROCESS FOR THE DIRECT AMINATION OF ALCOHOLS USING AMMONIA TO FORM PRIMARY AMINES BY MEANS OF A XANTPHOS CATALYST SYSTEM

The present invention relates to a chemocatalytic liquid-phase process for the direct one-stage amination of alcohols to primary amines by means of ammonia in high yields using a catalyst system containing at least one transition metal compound and a xantphos ligand. 2. The process according to claim 1 ,wherein{'sup': 1', '2', '3', '4, 'sub': 3', '2, 'R=R=R=R=phenyl, and A=—C(CH)—.'}3. The process according to claim 1 ,whereinthe xantphos ligand is carbonylchlorohydrido[9,9-dimethyl-4,5-bis(diphenylphosphino)xantheno]ruthenium(II)].4. The process according to claim 1 ,whereinthe alcohol is an aliphatic, linear ω-hydroxycarboxylic acid having a carbon chain comprising at least 8 carbon atoms.5. The process according to claim 1 ,whereinthe alcohol has a concentration of from 0.1 to 1000 mmol/l, based on the fluid phase.6. The process according to claim 1 ,wherein the contacting comprises contacting with liquid or supercritical ammonia, with a solution of ammonium salts in a solvent, or both.7. The process according to claim 1 ,wherein in the contacting,the ammonia has a molar ratio to hydroxyl groups in the alcohol of at least 5:1.8. The process according to claim 1 ,wherein the contacting is carried out at a pressure of from 1 to 1000 bar.9. The process according to claim 1 ,wherein the contacting is carried out in a temperature range of from 80 to 220° C.10. The process according to claim 1 ,whereina volume ratio of a liquid phase to a gas phase in the contacting is greater than or equal to 0.05.11. The process according to claim 1 ,wherein the process is carried out in an absence of hydrogen.12. The process according to claim 1 , wherein the alcohol has a concentration of from 0.1 to 100 mmol/l based on the fluid phase.13. The process according to claim 1 , wherein the alcohol has a concentration of from 0.1 to 10 mmol/l based on the fluid phase.14. The process according to claim 1 , wherein in the contacting claim 1 , the ammonia has a molar ratio to hydroxyl ...

PROCESS FOR BROMINATING ALKYLTHIOPHENES

What is described is a process for brominating alkylthiophene, in which an alkylthiophene of the general formula (I) where R is a branched or unbranched alkyl radical having 1 to 12 carbon atoms is contacted with stoichiometric amounts of HBr and H2O2, optionally in the presence of a solvent.

Process for preparing cyanopyridines and suitable catalysts therefor

The invention relates to a method for the manufacture of cyanopyridines from methylpyridines by their conversion with ammonia and oxygen and catalysts suitable therefor which contain further transition metals in addition to vanadium and phosphorus.

VIDEO-ON-DEMAND SYSTEM

A video-on-demand system including a video server storing video-on-demand content and for streaming video-on-demand through a first layer of an internet page having a first layer and a second layer; and a controller for causing there to be formed in the second layer a plurality of selectable overlay images such that a user at a location in communication with the internet remote from the video server and the controller can display streamed video-on-demand of the first layer in combination with the overlay images of the second layer and can select one of the overlay images; wherein the overlay images correspond to respective control functions for the video-on-demand stream; and the controller is responsive to selection of an overlay image to change the video-on-demand stream in accordance with the corresponding respective control function.

PREPARATION OF PRIMARY DIAMINES HAVING A LINEAR MAIN CHAIN FOR POLYAMIDE SYNTHESES

The invention provides a method to produce primary diamines by catalytic conversion of diols having a linear main chain of from 4 to 31 carbon atoms into the corresponding diamines. The reaction is conducted in a liquid or supercritical phase and is catalyzed by a homogeneous ruthenium-containing complex. The primary diamines obtained may be suitable for polyamide syntheses.

Method and device for producing shell catalysts

Disclosed herein is a process and an apparatus for producing coated catalysts. A process of the present disclosure includes providing a composition containing a liquid and a catalytically active material and/or a precursor thereof in a stock vessel, providing a support material in a vessel which is rotatable about a longitudinal axis, transporting the composition from the stock vessel through a first conduit to a spray nozzle, transporting a propellant fluid through a second conduit to the spray nozzle, atomizing the composition and propellant fluid in the nozzle to produce an aerosol that flows into the vessel and impregnates the support material present therein, heating the vessel so the liquid present in the aerosol evaporates from the support material and the finely divided support material which has been treated with catalytically active material and/or a precursor thereof is dried, and discharging the vaporized liquid from the vessel.

Device and method for detecting a reliability of integrated semiconductor components at high temperatures

The invention relates to a device and a method for detecting the reliability of integrated semiconductor components. The device includes a carrier substrate for receiving an integrated semiconductor component that will be examined, a heating element, and a temperature sensor. The temperature sensor has at least a portion of a parasitic functional element of the semiconductor component. As a result, reliability tests can be carried out in a particularly accurate and space-saving manner.

Method for preparation of dicarboxylic acids from saturated hydrocarbons or cycloaliphatic hydrocarbons by catalytic oxidation

The present invention relates to a method for preparing dicarboxylic acids from saturated and cycloaliphatic hydrocarbons by oxidation at a reaction temperature comprised in the range of 25 to 300° C. in an autoclave using a solid heterogeneous catalyst. More particularly, the method of the invention relates to a method for preparing adipic acid (AA) from cyclohexane (CH) by selective oxidation.

Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof

The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydrocodone (morphinan-6-one, 4,5-alpha-epoxy-3-methoxy-17-methyl) to form novel prodrugs/compositions of hydrocodone, including benzoates and heteroaryl carboxylic acids, which have a decreased potential for abuse of hydrocodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology. 1. A composition comprising at least one conjugate , the conjugate comprising hydrocodone and at least one benzoic acid , a derivative thereof , a salt thereof , or a combination thereof.3. The composition of claim 1 , wherein at least one benzoic acid or benzoic acid derivative is an aminobenzoate claim 1 , a hydroxybenzoate claim 1 , an aminohydroxybenzoate claim 1 , a derivative thereof claim 1 , or combination thereof.4. The composition of claim 3 , wherein the aminobenzoate is selected from the group consisting of: anthranilic acid claim 3 , 3-aminobenzoic acid claim 3 , 4 claim 3 ,5-dimethylanthranilic acid claim 3 , N-methylanthranilic acid claim 3 , N-acetylanthranilic acid claim 3 , fenamic acids (e.g. claim 3 , tolfenamic acid claim 3 , mefenamic acid claim 3 , flufenamic acid) claim 3 , 2 claim 3 ,4-diaminobenzoic acid (2 claim 3 ,4-DABA) claim 3 , 2-acetylamino-4-aminobenzoic acid claim 3 , 4-acetylamino-2-aminobenzoic acid claim 3 , 2 claim 3 ,4-diacetylaminobenzoic acid claim 3 , derivatives thereof and combinations thereof.5. The composition of claim 3 , wherein the hydroxybenzoate is selected from the group consisting of salicylic acid claim 3 , acetylsalicylic acid (aspirin) claim 3 , 3-hydroxybenzoic acid claim 3 , 4-hydroxybenzoic acid claim 3 , 6-methylsalicylic acid claim 3 , o claim 3 ,m claim 3 ,p-cresotinic acid claim 3 , anacardic acids claim 3 , 4 claim 3 ,5-dimethylsalicylic acid claim 3 , o claim 3 ,m claim 3 ,p-thymotic acid claim 3 , diflusinal ...

Water-Soluble Meloxicam Granules

Water soluble meloxicam granules comprising: 2. The water soluble meloxicam granules according to claim 1 , wherein the salt forming agent is meglumine.3. The water soluble meloxicam granules according to claim 1 , wherein the binder is selected from hydroxypropylmethylcellulose claim 1 , polyvinylpyrrolidone claim 1 , gelatine claim 1 , starch claim 1 , or polyethylene glycol ether.4. The water soluble meloxicam granules according to claim 2 , wherein the binder is selected from hydroxypropylmethylcellulose claim 2 , polyvinylpyrrolidone claim 2 , gelatine claim 2 , starch claim 2 , or polyethylene glycol ether.5. The water soluble meloxicam granules according to claim 1 , wherein the sugar or sweetener is selected from sodium saccharine claim 1 , aspartame claim 1 , and acesulfame potassium.6. The water soluble meloxicam granules according to claim 2 , wherein the sugar or sweetener is selected from sodium saccharine claim 2 , aspartame claim 2 , and acesulfame potassium.7. The water soluble meloxicam granules according to claim 3 , wherein the sugar or sweetener is selected from sodium saccharine claim 3 , aspartame claim 3 , and acesulfame potassium.8. The water soluble meloxicam granules according to claim 4 , wherein the sugar or sweetener is selected from sodium saccharine claim 4 , aspartame claim 4 , and acesulfame potassium.9. The water soluble meloxicam granules according to claim 1 , wherein the flavoring agent is selected from vanilla claim 1 , honey flavoring claim 1 , apple flavoring claim 1 , or contramarum.10. The water soluble meloxicam granules according to claim 2 , wherein the flavoring agent is selected from vanilla claim 2 , honey flavoring claim 2 , apple flavoring claim 2 , or contramarum.11. The water soluble meloxicam granules according to claim 3 , wherein the flavoring agent is selected from vanilla claim 3 , honey flavoring claim 3 , apple flavoring claim 3 , or contramarum.12. The water soluble meloxicam granules according to claim 4 , ...

System and Method of Biomechanical Posture Detection and Feedback

A system and method are described herein for a sensor device which biomechanically detects in real-time a user's movement state and posture and then provides real-time feedback to the user based on the user's real-time posture. The feedback is provided through immediate sensory feedback through the sensor device (e.g., a sound or vibration) as well as through an avatar within an associated application with which the sensor device communicates. 1. A method of providing postural feedback comprising:receiving by a microprocessor at repeated intervals data from a tri-axial accelerometer, the microprocessor and the tri-axial accelerometer comprising a sensor device attached to a user, the sensor device further comprising memory, an actuator, and a power source;normalizing by the microprocessor the received accelerometer data;determining by the microprocessor a postural description of the user based on the normalized received accelerometer data; andtriggering by the microprocessor the actuator to output sensory feedback based on the postural description of the user.2. The method of further comprising transmitting across a wireless electronic communication connection to a computing device the postural description of the user and the normalized received accelerometer data.3. The method of wherein the postural description comprises a current movement state.4. The method of wherein determining the postural description based on the normalized received accelerometer data comprises:computing feature vectors for the normalized received accelerometer data;quantizing the feature vectors;assigning the feature vectors to Gaussian distributions;acquiring distribution histograms for multiple movement states; andcomparing the distribution histograms to determine the current movement state from the multiple movement states.5. The method of wherein determining the postural description based on the normalized received accelerometer data comprises calculating a pelvic tilt angle of the user ...

BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF

The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydromorphone (4,5-α-epoxy-3-hydroxy-17-methyl morphinan-6-one) to form novel prodrugs/compositions of hydromorphone. The hydromorphone prodrugs of the present technology have decreased side effects and decreased potential for abuse compared to unconjugated hydromorphone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology. 1. A prodrug composition comprising at least one conjugate , the conjugate comprising at least one hydromorphone , and at least one aryl carboxylic acid.2. The prodrug composition of claim 1 , wherein the at least one aryl carboxylic acid is selected from the group consisting of benzoates and heteroaryl carboxylic acids.3. The prodrug composition of claim 2 , wherein the heteroaryl carboxylic acid is selected from the group consisting of pyridine claim 2 , diazine and triazine.5. The prodrug composition of claim 2 , wherein the benzoate is selected from the group consisting of aminobenzoates claim 2 , hydroxybenzoates and aminohydroxybenzoates claim 2 , mixtures thereof and derivatives thereof.6. The prodrug composition of claim 5 , wherein the aminobenzoate is selected from the group consisting of anthranilic acid claim 5 , 3-aminobenzoic acid claim 5 , 4 claim 5 ,5-dimethylanthranilic acid claim 5 , N-methylanthranilic acid claim 5 , N-acetylanthranilic acid claim 5 , fenamic acids claim 5 , 2 claim 5 ,4-diaminobenzoic acid (2 claim 5 ,4-DABA) claim 5 , 2-acetylamino-4-aminobenzoic acid claim 5 , 4-acetylamino-2-aminobenzoic acid and 2 claim 5 ,4-diacetylaminobenzoic acid claim 5 , mixtures thereof and derivatives thereof.7. The prodrug composition of claim 5 , wherein the hydroxybenzoate is selected from the group consisting of benzoic acid claim 5 , salicylic acid claim 5 , acetylsalicylic acid (aspirin) claim 5 , 3-hydroxybenzoic ...

System and Method of Biomechanical Posture Detection and Feedback Including Sensor Normalization

A system and method are described herein for a sensor device which biomechanically detects in real-time a user's movement state and posture and then provides real-time feedback to the user based on the user's real-time posture. The feedback is provided through immediate sensory feedback through the sensor device (e.g., a sound or vibration) as well as through an avatar within an associated application with which the sensor device communicates. The sensor device detects the user's movement state and posture by capturing data from a tri-axial accelerometer in the sensor device. Streamed data from the accelerometer is normalized to correct for sensor errors as well as variations in sensor placement and orientation. Normalization is based on accelerometer data collected while the user is wearing the device and performing specific actions. 1. A method of normalizing accelerometer data comprising:capturing, by a tri-axial accelerometer attached to a user, first tri-axial accelerometer data over a first period of time while the user is moving as instructed;averaging, by a microprocessor, the captured first tri-axial accelerometer data;creating, by the microprocessor, a first normalization matrix based on the averaged first tri-axial accelerometer data;capturing, by the tri-axial accelerometer attached to the user, second tri-axial accelerometer data at a second point in time; andcreating, by the microprocessor, first normalized accelerometer data by applying the first normalization matrix to the captured second tri-axial accelerometer data.2. The method of further comprising claim 1 , before averaging by the microprocessor the captured first tri-axial accelerometer data:calculating, by the microprocessor, smoothed power from the captured first tri-axial accelerometer data;identifying, by the microprocessor, data in the captured first tri-axial accelerometer data which results in the calculated power being below a threshold; anddiscarding, by the microprocessor, the ...

System and Method for Creating Custom Composite Images from Layered Images in a Client-Server Environment

In response to receiving a request from a client device, a first image can be determined based at least in part on an image identification in the request. The first image may be associated with a plurality of layers. A subset of the plurality of layers can be determined. Information configured to enable a selection of at least one layer in the subset may be sent to the client device. In response to receiving a request from a client device, a composite image can be obtained based at least in part on a selection of at least one layer of a plurality of layers of an image received in the request. The composite image may be dynamically generated or retrieved from a storage device. The composite image and/or information associated with the composite image can be sent to the client device.

Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Use Thereof

The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydrocodone (morphinan-6-one, 4,5-alpha-epoxy-3-methoxy-17-methyl) to form novel prodrugs/compositions of hydrocodone, including benzoates and heteroaryl carboxylic acids, which have a decreased potential for abuse of hydrocodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology. 2. The composition of claim 1 , wherein the conjugate is used to treat narcotic or opioid abuse; to reduce narcotic or opioid withdrawal; to treat moderate to severe pain; to reduce oral claim 1 , intranasal or intravenous drug abuse; or to provide oral claim 1 , intranasal or parenteral drug abuse resistance.3. The composition of claim 1 , wherein the conjugate exhibits an improved AUC and rate of release over time when compared to unconjugated hydrocodone over the same time period; exhibits less variability in the oral PK profile when compared to unconjugated hydrocodone; or has reduced side effects when compared with unconjugated hydrocodone.4. The composition of claim 1 , wherein the conjugate is provided in a dosage form selected from the group consisting of: a tablet claim 1 , a capsule claim 1 , a caplet claim 1 , a suppository claim 1 , a troche claim 1 , a lozenge claim 1 , an oral powder claim 1 , a solution claim 1 , an oral film claim 1 , a thin strip claim 1 , a slurry claim 1 , and a suspension.5. The composition of claim 1 , wherein the conjugate is provided in an amount sufficient to provide a therapeutically bioequivalent AUC when compared to unconjugated hydrocodone.6. The composition of claim 1 , wherein the conjugate is provided in an amount sufficient to provide a therapeutically bioequivalent AUC and Cwhen compared to an equivalent molar amount of unconjugated hydrocodone.7. The composition of claim 1 , wherein the conjugate is provided in an amount ...

Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Use Thereof

The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydrocodone (morphinan-6-one, 4,5-alpha-epoxy-3-methoxy-17-methyl) to form novel prodrugs/compositions of hydrocodone, including benzoates and heteroaryl carboxylic acids, which have a decreased potential for abuse of hydrocodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology. 2. The prodrug of claim 1 , wherein the conjugate is used to treat narcotic or opioid abuse; to reduce narcotic or opioid withdrawal; to treat moderate to severe pain; to reduce oral claim 1 , intranasal or intravenous drug abuse; or to provide oral claim 1 , intranasal or parenteral drug abuse resistance.3. The prodrug of claim 1 , wherein the conjugate exhibits an improved AUC and rate of release over time when compared to unconjugated hydrocodone over the same time period; exhibits less variability in the oral PK profile when compared to unconjugated hydrocodone; or has reduced side effects when compared with unconjugated hydrocodone.4. The prodrug of claim 3 , wherein the reduced side effect is gastrointestinal dysfunction.5. The prodrug of claim 4 , wherein the gastrointestinal dysfunction is constipation claim 4 , decreased hydrochloric acid secretion in the stomach claim 4 , decreased gastric motility claim 4 , esophageal reflux or combinations thereof.6. The prodrug of claim 1 , wherein the conjugate is provided in a dosage form selected from the group consisting of: a tablet claim 1 , a capsule claim 1 , a caplet claim 1 , a suppository claim 1 , a troche claim 1 , a lozenge claim 1 , an oral powder claim 1 , a solution claim 1 , an oral film claim 1 , a thin strip claim 1 , a slurry claim 1 , and a suspension.7. The prodrug of claim 6 , wherein the dosage form further comprises at least one excipient.8. The prodrug of claim 7 , wherein the excipient is an ...

Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Use Thereof

The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydrocodone (morphinan-6-one, 4,5-alpha-epoxy-3-methoxy-17-methyl) to form novel prodrugs/compositions of hydrocodone, including benzoates and heteroaryl carboxylic acids, which have a decreased potential for abuse of hydrocodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology.

TILTING MULTIPLIER

A tilting carrier assembly for a finishing process includes a load bar configured to convey a work piece relative to a work station. A skid is configured to receive the work piece. Each of a pair of links is pivotally coupled to the load bar at a first end and pivotally coupled to the skid at an opposite second end. A horizontal span between the first ends of the pair of links is substantially greater than a horizontal span between the second ends of the pair of links. 1. A tilting carrier assembly comprising:a load bar configured to convey a work piece relative to a work station;a skid configured to receive the work piece; anda pair of links, each of the links being pivotally coupled to the load bar at a first end and pivotally coupled to the skid at an opposite second end,wherein a length between the first ends of the pair of links is substantially greater than a length between the second ends of the pair of links.2. The tilting carrier assembly of claim 1 , wherein the skid is responsive to tilt without a drive force other than gravity when the load bar is tilted relative to horizontal.3. The tilting carrier assembly of claim 1 , wherein the length between the second ends of the pair of links is 70 percent or less than the length between the first ends of the pair of links.4. The tilting carrier assembly of claim 1 , wherein the length between the second ends of the pair of links is 50 percent or less than the length between the first ends of the pair of links.5. The tilting carrier assembly of claim 1 , wherein the length between the second ends of the pair of links is between about 40 percent and about 55 percent of the length between the first ends of the pair of links.6. The tilting carrier assembly of claim 1 , wherein each of the pair of links is a rigid member.7. The tilting carrier assembly of claim 1 , wherein each of the pair of links is a non-rigid member.8. The tilting carrier assembly of claim 1 , wherein the pair of links are centered along both the ...

METHOD OF MAKING AND USING NANO-BIMETALLIC CATALYST TO PRODUCE ADIPIC ACID

A bimetallic catalyst supported on a transition metal oxide is described. A method to make and use the bimetallic catalyst is also described. A method for preparing supported bimetallic catalysts of coinage group metal and a combination of a coinage group metal and a platinum metal group is described. A method for direct synthesis of adipic acid (AA) adopting green catalytic oxidation route of cyclohexane (CH) using the bimetallic catalysts is described. The reaction to convert CH into AA in the presence of bimetallic catalyst is carried in an autoclave in the temperature range of 25 to 300° C. The CH conversion was over 21% with AA selectivity of 34% and ca. 63% selectivity of cyclohexanone and cyclohexanol together over Au—Pd/TiObimetallic catalyst. 1. A nano-bimetallic catalyst , comprising:a coinage metal group;a platinum metal group; andat least one of a transition metal and a rare earth metal oxide in powder form for support to prepare adipic acid from cyclohexane.2. The nano-bimetallic catalyst of claim 1 , wherein the coinage group of metal is at least one of copper (Cu) claim 1 , silver (Ag) claim 1 , or gold (Au).3. The nano-bimetallic catalyst of claim 2 , wherein the coinage group of metal is at least one of the silver and gold.4. The nano-bimetallic catalyst of claim 1 , wherein the platinum group of metal is at least one of ruthenium claim 1 , rhodium claim 1 , palladium claim 1 , osmium claim 1 , iridium claim 1 , and platinum.5. The nano-bimetallic catalyst of claim 4 , wherein the platinum group of metal is palladium.6. The nano-bimetallic catalyst of claim 1 , wherein the support is a transition metal oxide claim 1 , wherein the transition metal is titanium.7. A method of making the nano-bimetallic catalyst claim 1 , comprising:dissolving tetracholoroauric acid and potassium carbonate in distilled water to make a first solution;dissolving a platinum group of metal chloride in water to make a second solution;heating the second solution and adding ...

SYSTEM AND METHOD OF BIOMECHANICAL POSTURE DETECTION AND FEEDBACK INCLUDING SENSOR NORMALIZATION

A system and method are described herein for a sensor device which biomechanically detects in real-time a user's movement state and posture and then provides real-time feedback to the user based on the user's real-time posture. The feedback is provided through immediate sensory feedback through the sensor device (e.g., a sound or vibration) as well as through an avatar within an associated application with which the sensor device communicates. The sensor device detects the user's movement state and posture by capturing data from a tri-axial accelerometer in the sensor device. Streamed data from the accelerometer is normalized to correct for sensor errors as well as variations in sensor placement and orientation. Normalization is based on accelerometer data collected while the user is wearing the device and performing specific actions. 12.-. (canceled)3. An apparatus comprising: at least one movement sensor comprising an accelerometer and a gyroscope;', 'a feedback apparatus; and', receive data from the at least one movement sensor regarding movement of the user;', 'normalize the received data;', 'use an activity detection algorithm to ascertain a postural description of the user based on the normalized received data, the postural description comprising at least one movement state; and', 'trigger the feedback apparatus based on the postural description of the user., 'a microprocessor configured to], 'a sensor system configured to be worn by a user, the sensor system comprising4. The apparatus of claim 3 , wherein the processor is operative to:compute a sequence of movement data features from the normalized movement data; andanalyze the sequence of movement data features according to a rule-based model to determine, in part, the postural description.5. The apparatus of claim 3 , wherein the processor is operative tocompute a sequence of movement data features from the normalized movement data; andcompare the sequence of movement data features according to a movement ...

AUGMENTED REALITY SYSTEM FOR CONVEYOR SYSTEM AND METHOD

An augmented reality system includes a display device defining a display area, a database containing a three-dimensional model of a conveyor system, a communication link between the database and the display device, and a processor. The processor is operable to display the three-dimensional model of the conveyor system on the display area. The display allows a human user to see a real time combined view of the real physical environment, including a building and features thereof, and the three-dimensional model of the factory automation system within the building. A user interface has controls operable to effect one or both of: movement of the displayed conveyor system within the building, and measurement between features of the building and the displayed conveyor system. 1. An augmented reality system comprising:a display device defining a display area;a database containing a three-dimensional model of a conveyor system;a communication link between the database and the display device;a processor operable to display the three-dimensional model of the conveyor system on the display area, wherein the display allows a human user to see a real time combined view of the real physical environment, including a building and features thereof, and the three-dimensional model of the factory automation system within the building; anda user interface having controls operable to effect one or both of: movement of the displayed conveyor system within the building, and measurement between features of the building and the displayed conveyor system.2. The augmented reality system of claim 1 , wherein the display device includes eyewear claim 1 , and the display area is transparent or semi-transparent.3. The augmented reality system of claim 1 , wherein the electronic communication link is established through a wireless network.4. The augmented reality system of claim 1 , wherein the user interface has at least one control operable to effect starting of virtual operation of the ...

BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF

The presently described technology provides compositions comprising aryl carboxylic acids and, for example NSAIDs, chemically conjugated to oxymorphone (4,5-α-epoxy-3,14-dihydroxy-17-methylmorphinan-6-one) to form novel prodrugs/compositions of oxymorphone, including benzoates, salicylates, propionates, fenamates, and acetates, which have a decreased potential for abuse of oxymorphone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology. 2. A composition comprising at least one compound of claim 1 , a salt of said compound claim 1 , or a combination thereof.3. The composition of claim 2 , wherein the composition is in a dosage form selected from the group consisting of a tablet claim 2 , a capsule claim 2 , a caplet claim 2 , a soft gel claim 2 , a suppository claim 2 , a troche claim 2 , a lozenge claim 2 , an oral powder claim 2 , a solution claim 2 , an oral film claim 2 , a thin strip claim 2 , a slurry claim 2 , and a suspension.4. The composition of claim 2 , wherein the composition is in an amount sufficient to provide a therapeutically equivalent AUC when compared to unconjugated oxymorphone when administered orally.5. The composition of claim 2 , wherein the composition is in an amount sufficient to provide a therapeutically equivalent AUC and Cwhen compared to an equivalent molar amount of unconjugated oxymorphone when administered orally.6. The composition of claim 2 , wherein the composition is in an amount sufficient to provide a therapeutically equivalent AUC and a lower Cwhen compared to an equivalent molar amount of unconjugated oxymorphone when administered orally.7. The composition of claim 2 , wherein intranasal or intravenous administration of the compound provides a lower AUC and/or Cmax when compared to an equivalent molar amount of unconjugated oxymorphone.8. The composition of claim 2 , wherein oral administration of the compound provides a ...

VIDEO-ON-DEMAND SYSTEM

A video-on-demand system including a video server storing video-on-demand content and for streaming video-on-demand through a first layer of an internet page having a first layer and a second layer; and a controller for causing there to be formed in the second layer a plurality of selectable overlay images such that a user at a location in communication with the internet remote from the video server and the controller can display streamed video-on-demand of the first layer in combination with the overlay images of the second layer and can select one of the overlay images; wherein the overlay images correspond to respective control functions for the video-on-demand stream; and the controller is responsive to selection of an overlay image to change the video-on-demand stream in accordance with the corresponding respective control function. 1. (canceled)2. An electronic device comprising:an interface configured to receive video-on-demand content via a network;a processor configured to decode an internet page via which the video-on-demand content is received, the internet page including the first layer and a second layer and a link, and configured to send user selections via the interface wherein:an item of selected video-on-demand content is received in the first layer,an overlay image that can be selectively combined with the video-on-demand content of the first layer, is received in the second layer,the interface is further configured to receive a link in association with the overlay image, a user selection of the link causing advertising content to output for display, and whereinthe overlay image is of contextual relevance to the item of selected video-on-demand-content.3. The electronic device according to claim 2 , wherein the link is the address of a different internet page and the interface receives associated advertising content in the different internet page.4. The electronic device according to claim 2 , wherein selection of the link causes the interface to ...

SYSTEM AND METHOD FOR CHARACTERIZING BIOMECHANICAL ACTIVITY

A system and method for collecting a set of kinematic data streams from an activity tracking system with at least one activity monitoring system that is attached to a user; segmenting at least a subset of the kinematic data streams into a set of segments according to actions of the user; generating a set of biomechanical signals from the kinematic data streams wherein a biomechanical signal characterize a biomechanical property during a segment and includes generating a first integration data set through data integration and baseline error correction across the set of segments of the normalized kinematic data stream and determining at least a first biomechanical signal that is at least partially based on the first integration data set; and applying the set of biomechanical signals. 119.-. (canceled)20. A method for identifying movement activity of a user , comprising:receiving a plurality of kinematic raw data streams from a plurality of sensors, the plurality of sensors positioned adjacent to different regions of the user;normalizing the plurality of kinematic raw data streams into a plurality of normalized data streams;generating a set of biomechanical primitives based on the plurality of normalized data streams; andcontrolling a user feedback device based on the set of biomechanical primitives.21. The method of claim 20 , wherein each of the plurality of sensors comprises an accelerometer and a gyroscope.22. The method of claim 20 , wherein the plurality of kinematic raw data streams comprises acceleration claim 20 , velocity claim 20 , displacement claim 20 , force claim 20 , angular velocity claim 20 , angular displacement claim 20 , and tilt/angle.23. The method of claim 20 , wherein the plurality of kinematic data streams comprises at least one of acceleration claim 20 , velocity claim 20 , displacement claim 20 , force claim 20 , angular velocity claim 20 , angular displacement claim 20 , and tilt/angle.24. The method of claim 20 , wherein the set of ...

BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF

The presently described technology provides compositions comprising aryl carboxylic acids and, for example NSAIDs, chemically conjugated to oxycodone (4,5-α-epoxy-14-hydroxy-17-methylmorphinan-6-one) to form novel prodrugs/compositions of oxycodone, including benzoates, salicylates, propionates, fenamates, and acetates, which have a decreased potential for abuse of oxycodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology. 2. A composition comprising a compound of claim 1 , a salt thereof claim 1 , or a combination thereof.3. The composition of claim 2 , wherein the salt is a pharmaceutically acceptable salt.4. The composition of claim 3 , wherein the pharmaceutically acceptable salt is selected from the group consisting of an acetate claim 3 , L-aspartate claim 3 , besylate claim 3 , bicarbonate claim 3 , carbonate claim 3 , D-camsylate claim 3 , L-camsylate claim 3 , citrate claim 3 , edisylate claim 3 , formate claim 3 , fumarate claim 3 , gluconate claim 3 , hydrobromide/bromide claim 3 , hydrochloride/chloride claim 3 , D-lactate claim 3 , L-lactate claim 3 , D claim 3 ,L-lactate claim 3 , D claim 3 ,L-malate claim 3 , L-malate claim 3 , mesylate claim 3 , pamoate claim 3 , phosphate claim 3 , succinate claim 3 , sulfate claim 3 , bisulfate claim 3 , D-tartrate claim 3 , L-tartrate claim 3 , D claim 3 ,L-tartrate claim 3 , meso-tartrate claim 3 , benzoate claim 3 , gluceptate claim 3 , D-glucuronate claim 3 , hybenzate claim 3 , isethionate claim 3 , malonate claim 3 , methylsufate claim 3 , 2-napsylate claim 3 , nicotinate claim 3 , nitrate claim 3 , orotate claim 3 , stearate claim 3 , tosylate claim 3 , thiocyanate claim 3 , acefyllinate claim 3 , aceturate claim 3 , aminosalicylate claim 3 , ascorbate claim 3 , borate claim 3 , butyrate claim 3 , camphorate claim 3 , camphocarbonate claim 3 , decanoate claim 3 , hexanoate claim 3 , cholate claim 3 , ...

SYSTEM AND METHOD OF BIOMECHANICAL POSTURE DETECTION AND FEEDBACK

A system and method are described herein for a sensor device which biomechanically detects in real-time a user's movement state and posture and then provides real-time feedback to the user based on the user's real-time posture. The feedback is provided through immediate sensory feedback through the sensor device (e.g., a sound or vibration) as well as through an avatar within an associated application with which the sensor device communicates. 1. A method of providing postural feedback comprising:receiving by a microprocessor data from a tri-axial accelerometer, the microprocessor and the tri-axial accelerometer comprising a sensor device attached to a user, the sensor device further comprising an actuator;normalizing by the microprocessor the received accelerometer data; computing a sequence of accelerometer data features from the normalized received accelerometer data,', 'analyzing the sequence of accelerometer data features according to a rule-based model to determine, in part, the postural description; and, 'determining by the microprocessor a postural description of the user based on the normalized received accelerometer data, wherein the postural description comprises a movement state, wherein determining the postural description of the user comprisestriggering by the microprocessor the actuator to output sensory feedback based on the postural description of the user.2. The method of claim 1 , further comprising transmitting across a wireless electronic communication connection to a computing device the postural description of the user and the normalized received accelerometer data.3. The method of claim 1 , wherein determining the postural description based on the normalized received accelerometer data further comprises:computing feature vectors for the normalized received accelerometer data;quantizing the feature vectors;assigning the feature vectors to Gaussian distributions;acquiring distribution histograms for multiple movement states; andcomparing the ...

WASHING DEVICE

In a washing element holder (), which on one side is closed off relative to the outside(s) with a sponge material () having pores (), a washing device () has a washing element () which has at least one synthetic surfactant as a foaming substance and the principal constituent. 1. A washing device comprising:a washing element holder at least partially closed to an outside;a sponge material which has pores; anda washing element inserted into the washing element holder, wherein on at least one side the washing element holder is closed off relative to the outside with the sponge material and the washing element contains a least one synthetic surfactant as a foaming substance and as the principal constituent thereof250. A washing device according to claim 1 , wherein at least % of the washing element consists of the at least one surfactant.3. A washing device according to claim 1 , wherein the washing element is soap-free or is a syndet or is both soap-free and is a syndet.4. A washing device according to claim 1 , wherein washing element is in the form of a combar or the washing element comprises at least one synthetic surfactant and a soap portion with a soap.5. A washing device according to claim 1 , wherein:before use of the washing device the washing device allows for ventilating the washing element from outside or moistening the washing element from outside or both ventilating the washing element from outside and moistening the washing element from outside; andbefore use of the washing device the pores are essentially or completely free of surfactants or the pores are permeable to air or the pores are permeable to water or any combination of the pores are essentially or completely free of surfactants and the pores are permeable to air and the pores are permeable to water.6. A washing device according to claim 1 , wherein the washing element or the washing element holder or both the washing element or the washing element holder are surrounded by the sponge material ...

Pharmaceutically Acceptable Salts and Polymorphic Forms of Hydrocodone Benzoic Acid Enol Ester and Processes for Making Same

Compositions comprising hydrocodone benzoic acid enol ester to form novel prodrugs including hydrocodone benzoic acid enol ester salts, and various polymorphs. Also provided are processes for the preparation of hydrocodone benzoic acid enol ester salts, and various polymorphs. 183-. (canceled)84. A compound comprising a polymorphic form of hydrocodone benzoic acid enol ester hydrochloride , wherein the polymorphic form is Form I , wherein Form I has an x-ray powder diffraction pattern comprising peaks at about the following 2θ values: 9.05 , 12.32 , 13.16 , 14.94 , and 18.57.85. The compound of claim 84 , wherein Form I has an x-ray powder diffraction pattern further comprising peaks at about the following 2θ values: 6.16 claim 84 , 10.95 claim 84 , 11.91 claim 84 , 14.60 claim 84 , 17.04 claim 84 , 17.23 claim 84 , 17.80 claim 84 , 19.18 claim 84 , 20.66 claim 84 , 21.10 claim 84 , 22.15 claim 84 , 23.50 claim 84 , 26.07 claim 84 , and 28.39.86. A solid pharmaceutical composition comprising a therapeutically effective amount of a polymorphic form of hydrocodone benzoic acid enol ester hydrochloride and a pharmaceutically acceptable excipient in a formulation for oral administration claim 84 , wherein the polymorphic form is Form I claim 84 , wherein Form I has an x-ray powder diffraction pattern comprising peaks at about the following 2θ values: 9.05 claim 84 , 12.32 claim 84 , 13.16 claim 84 , 14.94 claim 84 , and 18.57.87. The solid pharmaceutical composition of claim 86 , wherein Form I has an x-ray powder diffraction pattern further comprising peaks at about the following 2θ values: 6.16 claim 86 , 10.95 claim 86 , 11.91 claim 86 , 14.60 claim 86 , 17.04 claim 86 , 17.23 claim 86 , 17.80 claim 86 , 19.18 claim 86 , 20.66 claim 86 , 21.10 claim 86 , 22.15 claim 86 , 23.50 claim 86 , 26.07 claim 86 , and 28.39.88. A method for treating pain in a patient comprising the step of selecting a patient that is in need of pain treatment claim 84 , administering to said ...

Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Uses Thereof

The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydrocodone (morphinan-6-one, 4,5-alpha-epoxy-3-methoxy-17-methyl) to form novel prodrugs/compositions of hydrocodone, including benzoates and heteroaryl carboxylic acids, which have a decreased potential for abuse of hydrocodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology. 1. A composition comprising 5 mg of benzoate-hydrocodone hydrochloride.2. The composition of wherein the composition is a conjugate.3. The composition of wherein the composition is a prodrug.4. The composition of wherein the 5 mg of benzoate-hydrocodone hydrochloride contains a molar equivalent of 3.4 mg of hydrocodone.5. The composition of wherein the mean AUCof hydrocodone is about 70.69 hours×ng/mL±17.39 hours×ng/mL when administered orally to a human.6. The composition of wherein the mean AUCof hydrocodone is about 79.37 hours×ng/mL±18.67 hours×ng/mL when administered orally to a human.7. The composition of wherein the mean Cof hydrocodone is about 12.8 ng/mL±3.84 ng/mL when administered orally to a human.8. The composition of wherein the mean Tof hydrocodone is about 1.866 hours±0.901 hours when administered orally to a human.9. The composition of wherein the median Tof hydrocodone is about 1.5 hours when administered orally to a human.10. The composition of wherein the range of Tof hydrocodone is from about 0.5 hours to 4 hours when administered orally to a human.11. The composition of wherein the mean tof hydrocodone is about 3.79 hours±0.88 hours when administered orally to a human.12. A composition comprising 6.67 mg of benzoate-hydrocodone hydrochloride.13. The composition of wherein the composition is a conjugate.14. The composition of wherein the composition is a prodrug.15. The composition of wherein the 6.67 mg of benzoate-hydrocodone hydrochloride contains a ...

Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydromorphone, Prodrugs, Methods of Making and Use Thereof

The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydromorphone (4,5-α-epoxy-3-hydroxy-17-methyl morphinan-6-one) to form novel prodrugs/compositions of hydromorphone. The hydromorphone prodrugs of the present technology have decreased side effects and decreased potential for abuse compared to unconjugated hydromorphone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology. 1. A composition comprising a hydromorphone conjugate wherein the hydromorphone conjugate is 6-o-Salicylate-hydromorphone , a derivative thereof , a pharmaceutically acceptable salt thereof , or a combination thereof.3. The composition of claim 1 , wherein the at least one hydromorphone conjugate and/or at least one pharmaceutically acceptable salt thereof is used to treat narcotic or opioid abuse; to prevent narcotic or opioid withdrawal; to treat moderate to severe pain; to reduce or prevent oral claim 1 , intranasal or intravenous drug abuse; or to provide oral claim 1 , intranasal claim 1 , or parenteral drug abuse resistance.4. The composition of claim 1 , wherein the at least one hydromorphone conjugate and/or at least one pharmaceutically acceptable salt thereof is provided in a dosage form selected from the group consisting of a tablet claim 1 , a capsule claim 1 , a caplet claim 1 , a suppository claim 1 , a troche claim 1 , a lozenge claim 1 , a powder claim 1 , a solution claim 1 , a film claim 1 , a thin strip claim 1 , a slurry claim 1 , a suspension claim 1 , a gel claim 1 , a strip claim 1 , a rectal film claim 1 , a transdermal patch claim 1 , a syrup claim 1 , and an inhalation compound.5. The composition of claim 1 , wherein the composition is formulated for oral administration.6. The composition of claim 5 , wherein oral administration of the at least one hydromorphone conjugate and/or at least one pharmaceutically ...

BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF

The presently described technology provides compositions comprising aryl carboxylic acids and, for example NSAIDs, chemically conjugated to oxycodone (4,5-α-epoxy-14-hydroxy-17-methylmorphinan-6-one) to form novel prodrugs/compositions of oxycodone, including benzoates, salicylates, propionates, fenamates, and acetates, which have a decreased potential for abuse of oxycodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology. 1. A composition comprising an oxycodone conjugate wherein the oxycodone is conjugated to 4-hydroxy-benzoic acid , derivative thereof , pharmaceutically acceptable salt thereof , or a combination thereof.3. The composition of claim 1 , wherein the oxycodone conjugate exhibits an improved AUC and rate of release over time when compared to unconjugated oxycodone over the same time period; exhibits less variability in the oral PK profile when compared to unconjugated oxycodone; or has reduced side effects when compared with unconjugated oxycodone.4. The composition of claim 3 , wherein the reduced side effects comprise reduced opioid induced constipation.5. The composition of claim 1 , wherein the composition is formulated for oral administration.6. The composition of claim 5 , wherein the composition formulated for oral administration is a tablet claim 5 , capsule claim 5 , caplet claim 5 , pill claim 5 , powder claim 5 , troche claim 5 , lozenge claim 5 , slurry claim 5 , liquid solution claim 5 , suspension claim 5 , emulsion claim 5 , elixir or oral thin film (OTF).7. The composition of claim 1 , wherein the composition in a solid form claim 1 , a solution claim 1 , a suspension claim 1 , or a soft gel form.8. The composition of claim 7 , wherein the solid form further comprises excipients claim 7 , binders claim 7 , derivatives thereof claim 7 , or combinations thereof.9. The composition of claim 8 , wherein the binder is povidone.10. The ...

METHOD AND DEVICE FOR PRODUCING SHELL CATALYSTS

Disclosed herein is a process and an apparatus for producing coated catalysts. A process of the present disclosure includes providing a composition containing a liquid and a catalytically active material and/or a precursor thereof in a stock vessel, providing a support material in a vessel which is rotatable about a longitudinal axis, transporting the composition from the stock vessel through a first conduit to a spray nozzle, transporting a propellant fluid through a second conduit to the spray nozzle, atomizing the composition and propellant fluid in the nozzle to produce an aerosol that flows into the vessel and impregnates the support material present therein, heating the vessel so the liquid present in the aerosol evaporates from the support material and the finely divided support material which has been treated with catalytically active material and/or a precursor thereof is dried, and discharging the vaporized liquid from the vessel. 1. A process for producing coated catalysts , comprising:a) providing a composition containing a liquid and at least one of a catalytically active material or a precursor thereof in a stock vessel;b) providing support material in a vessel which is rotatable about a longitudinal axis;c) transporting the composition from the stock vessel through a first conduit to a spray nozzle;d) transporting a propellant fluid through a second conduit to the spray nozzle;e) atomizing the composition and propellant fluid in the nozzle to produce an aerosol which flows into the vessel and impregnates the support material present therein;f) heating the vessel so that the liquid present in the aerosol evaporates from the support material and the support material which has been treated with catalytically active material and/or a precursor thereof is dried; andg) at least one of discharging or extracting the vaporized liquid from the vessel.2. The process of claim 1 , wherein the spraying fluid is an inert gas which is heated before transport through ...

System and method of biomechanical posture detection and feedback including sensor normalization

A system and method are described herein for a sensor device which biomechanically detects in real-time a user's movement state and posture and then provides real-time feedback to the user based on the user's real-time posture. The feedback is provided through immediate sensory feedback through the sensor device (e.g., a sound or vibration) as well as through an avatar within an associated application with which the sensor device communicates. The sensor device detects the user's movement state and posture by capturing data from a tri-axial accelerometer in the sensor device. Streamed data from the accelerometer is normalized to correct for sensor errors as well as variations in sensor placement and orientation. Normalization is based on accelerometer data collected while the user is wearing the device and performing specific actions. 1. A method comprising:capturing, by a tri-axial accelerometer attached to a user, first tri-axial accelerometer data over a first period of time while the user is walking;averaging, by a microprocessor, the captured first tri-axial accelerometer data;creating, by the microprocessor, a first normalization matrix for vertical alignment based on the averaged first tri-axial accelerometer data;capturing, by the tri-axial accelerometer attached to the user, second tri-axial accelerometer data over a second period of time, while the user is stationary;averaging, by the microprocessor, the captured second tri-axial accelerometer data;creating, by the microprocessor, a second normalization matrix for lateral alignment based on an averaged third tri-axial accelerometer data;capturing, by the tri-axial accelerometer attached to the user, third tri-axial accelerometer data at a third point in time;creating, by the microprocessor, normalized accelerometer data by applying the first normalization matrix and the second normalization matrix to the captured third tri-axial accelerometer data; andanalyzing at least the normalized accelerometer data ...

Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Use Thereof

The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydrocodone (morphinan-6-one, 4,5-alpha-epoxy-3-methoxy-17-methyl) to form novel prodrugs/compositions of hydrocodone, including benzoates and heteroaryl carboxylic acids, which have a decreased potential for abuse of hydrocodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology. 117-. (canceled)19. The composition of claim 18 , wherein the conjugate is used to treat narcotic or opioid abuse; to reduce narcotic or opioid withdrawal; to treat moderate to severe pain; to reduce oral claim 18 , intranasal or intravenous drug abuse; or to provide oral claim 18 , intranasal or parenteral drug abuse resistance.20. The composition of claim 18 , wherein the conjugate exhibits an improved AUC and rate of release over time when compared to unconjugated hydrocodone over the same time period; exhibits less variability in the oral PK profile when compared to unconjugated hydrocodone; or has reduced side effects when compared with unconjugated hydrocodone.21. The composition of claim 18 , wherein the conjugate is provided in a dosage form selected from the group consisting of: a tablet claim 18 , a capsule claim 18 , a caplet claim 18 , a suppository claim 18 , a troche claim 18 , a lozenge claim 18 , an oral powder claim 18 , a solution claim 18 , an oral film claim 18 , a thin strip claim 18 , a slurry claim 18 , and a suspension.22. The composition of claim 18 , wherein the conjugate is provided in an amount sufficient to provide a therapeutically bioequivalent AUC when compared to unconjugated hydrocodone.23. The composition of claim 18 , wherein the conjugate is provided in an amount sufficient to provide a therapeutically bioequivalent AUC and Cwhen compared to an equivalent molar amount of unconjugated hydrocodone.24. The composition of claim 18 , wherein the ...

Incident prediction and response using deep learning techniques and multimodal data

In an approach to incident prediction and response, one or more computer processors receive one or more alerts corresponding to an incident. The one or more computer processors aggregate the one or more alerts with additional data corresponding to the incident. The one or more computer processors feed the aggregated data into a prediction model, where training of the prediction model uses associated independent stacked Restricted Boltzmann Machines utilizing one or more supervised methods and one or more unsupervised methods. The one or more computer processors determine, based, at least in part, on one or more calculations by the prediction model, at least one probability of the incident. The one or more computer processors determine whether the at least one probability exceeds a pre-defined threshold. In response to determining the at least one probability exceeds a pre-defined threshold, the one or more computer processors send at least one notification.

SYSTEM AND METHOD FOR CHARACTERIZING BIOMECHANICAL ACTIVITY

A system and method for collecting a set of kinematic data streams from an activity tracking system with at least one activity monitoring system that is attached to a user; segmenting at least a subset of the kinematic data streams into a set of segments according to actions of the user; generating a set of biomechanical signals from the kinematic data streams wherein a biomechanical signal characterize a biomechanical property during a segment and includes generating a first integration data set through data integration and baseline error correction across the set of segments of the normalized kinematic data stream and determining at least a first biomechanical signal that is at least partially based on the first integration data set; and applying the set of biomechanical signals. 1. A method for personal activity monitoring comprising:collecting a set of kinematic data streams from an activity tracking system with at least one activity monitoring system that is attached to a user;segmenting at least a subset of the kinematic data streams into a set of segments according to actions of the user; generating a first integration data set through data integration and baseline error correction across the set of segments of the kinematic data stream, and', 'determining at least a first biomechanical signal that is at least partially based on the first integration data set; and, 'generating a set of biomechanical signals from the kinematic data streams wherein a biomechanical signal is a time series signal with values that characterize a biomechanical property during a segment, wherein generating the set of biomechanical signals comprisesapplying the set of biomechanical signals.2. The method of claim 1 , wherein the activity monitoring system is a single activity monitoring device.3. The method of claim 1 , wherein the activity monitor system is a set of sensor devices that are each attached at distinct points on the user.4. The method of claim 1 , wherein segmenting at ...

SYSTEM AND METHOD FOR RUN TRACKING WITH A WEARABLE ACTIVITY MONITOR

A system and method for tracking running activity that includes an activity monitor device with an inertial measurement system, a communication module, a processor configured to generate a set of biomechanical signals from kinematic data collected from the inertial measurement system, a housing that internally contains the inertial measurement system, the communication module, and the processor, and an electrical interface exposed on the external side of the housing; and a user application operable on a second computing device distinct from the activity monitor device; wherein communication and generation of biomechanical signals are operable in many modes. 1. A system for tracking running activity comprising: an inertial measurement system,', 'a communication module,', 'a processor configured to generate a set of biomechanical signals from kinematic data collected from the inertial measurement system, and', 'a housing that internally contains the inertial measurement, the communication module, and the processor;, 'an activity monitor device that comprisesa user application operable on a second computing device distinct from the activity monitor device; andwherein the communication module of the activity monitor device is configured to communicate the set of biomechanical signals to the user application.2. The system of claim 1 , wherein the set of biomechanical signals comprise the biomechanical signals of cadence claim 1 , vertical oscillation claim 1 , braking claim 1 , pelvic drop claim 1 , and pelvic rotation.3. The system of claim 2 , wherein the set of biomechanical signals comprise the biomechanical signals of left-right detection and ground contact time.4. The system of claim 1 , wherein values of biomechanical signal in the set of biomechanical signals map to a window of step segments.5. The system of claim 1 , wherein the processor enters a dynamic monitoring mode when the biomechanical signals satisfy a consistency condition or a performance condition; ...

SYSTEM AND METHOD FOR A WEARABLE TECHNOLOGY PLATFORM

A system and method for customizing biomechanical wearable sensors can include a customizable biomechanical processing layer, activity model layer, and/or device communication and processing management. The system and method can include monitoring biomechanical signals at a first set of wearable sensors configured in an initial biomechanical processing configuration; selecting a configuration option for the first set of wearable sensors; delivering the configuration option to the at least one wearable sensor; and monitoring biomechanical signals according to an altered biomechanical processing configuration that is altered according to the configuration option. 1. A method for customizing biomechanical wearable sensors comprising:at a first set of wearable sensors, collecting kinematic sensor data and applying an initial biomechanical processing configuration to convert the kinematic data into a set of biomechanical signals;at a remote computing resource, selecting a configuration option for the first set of wearable sensors;delivering the configuration option to the at least one wearable sensor;updating the initial biomechanical processing configuration of the first set of wearable sensors to an altered biomechanical processing configuration, wherein the altered biomechanical processing configuration is based in part on the first configuration option; andat the first set of wearable sensors, applying the altered biomechanical processing configuration to convert the kinematic data into a set of biomechanical signals.2. The method of claim 1 , wherein the biomechanical signals are running and walking biomechanical signals associated with a step-based biomechanical metrics.3. The method of claim 2 , wherein the biomechanical signals include cadence claim 2 , vertical step oscillation claim 2 , step braking claim 2 , pelvic drop claim 2 , and pelvic rotation.4. The method of claim 1 , wherein selecting a configuration option for the first set of wearable sensors ...

METHOD OF MAKING ADIPIC ACID USING NANO CATALYST

A method for direct synthesis of adipic acid (AA) adopting green catalytic oxidation route of cyclohexane (CH) using the bimetallic catalysts is described. The reaction to convert CH into AA in the presence of bimetallic catalyst is carried in an autoclave in the temperature range of 25 to 300° C. The CH conversion was over 21% with AA selectivity of 34% and ca. 63% selectivity of cyclohexanone and cyclohexanol together over Au—Pd/TiObimetallic catalyst. 1. A method of making adipic acid(AA) , comprising:oxidizing a cyclic paraffin mixed with a solvent using a gas, an inert atmosphere and a nano-bimetallic catalyst in an autoclave; andapplying a specific pressure and a specific temperature to the autoclave while oxidizing the cyclic paraffin to make adipic acid.215. The method of making adipic acid(AA) as in claim , wherein the cyclic paraffin is cyclohexane.315. The method of making adipic acid(AA) as in claim , wherein the gas is at least one of oxygen , air and mixture of oxygen and nitrogen.415. The method of making adipic acid(AA) as in claim , wherein the nano-bimetallic catalyst is AuPd/TiOcatalyst.515. The method of making adipic acid(AA) as in claim , wherein the temperature is between 50-250° C.615. The method of making adipic acid(AA) as in claim , wherein the specific pressure is at least one of atmospheric , sub-atmospheric and super-atmospheric. This application is a divisional application and claims priority to U.S. patent application Ser. 13/464904 filed on May 4, 2012. Pending application is hereby incorporated by reference in their entireties for all their teachings.The instant application relates to the production of Adipic acid (AA) from cyclohexane (CH) using a nano-bimetallic catalyst. The nano-bimetallic catalyst is specifically a combination of a coinage group metal and a platinum group metal.The selective oxidation of cyclohexane (CH) to adipic acid (AA) is an industrially important reaction for manufacturing various valuable materials such ...

BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF

The presently described technology provides methods of treating a patient having moderate to severe pain, narcotic or opioid abuse or narcotic or opioid withdrawal. The presently described methods are carried out by comprising administering to the patient a pharmaceutically effective amount of a composition comprising acetaminophen and benzoate-hydrocodone hydrochloride. The composition has reduced side effects when compared with unconjugated hydrocodone. 114-. (canceled)15. A method for treating a patient having moderate to severe pain , narcotic or opioid abuse; or narcotic or opioid withdrawal comprising administering to the patient a pharmaceutically effective amount of a composition of a conjugate of hydrocodone wherein the conjugate exhibits lower mean exposure to hydrocodone about more than 53 mg when compared to unconjugated hydrocodone; or has reduced side effects when compared with an equivalent molar amount of unconjugated hydrocodone.16. The method of claim 15 , wherein the composition is a prodrug.17. The method of claim 15 , wherein the composition is used to reduce or prevent oral claim 15 , intranasal or intravenous drug abuse; or to provide oral claim 15 , intranasal or parenteral drug abuse resistance.18. The method of claim 15 , wherein the composition exhibits an improved AUC and rate of release of hydrocodone over time when compared to an equivalent molar amount of unconjugated hydrocodone over the same time period.19. The method of claim 15 , wherein the composition is provided in a dosage form selected from the group consisting of: a tablet claim 15 , a capsule claim 15 , a caplet claim 15 , a suppository claim 15 , a troche claim 15 , a lozenge claim 15 , an oral powder claim 15 , a solution claim 15 , an oral film claim 15 , a thin strip claim 15 , a slurry claim 15 , and a suspension.20. The method of claim 15 , wherein the composition is provided in an amount sufficient to provide a therapeutically bioequivalent AUC for hydrocodone at ...

System and Method of Biomechanical Posture Detection and Feedback

A system and method are described herein for a sensor device which biomechanically detects in real-time a user's movement state and posture and then provides real-time feedback to the user based on the user's real-time posture. The feedback is provided through immediate sensory feedback through the sensor device (e.g., a sound or vibration) as well as through an avatar within an associated application with which the sensor device communicates. 1. A method of providing postural feedback comprising:receiving by a microprocessor at repeated intervals data from a tri-axial accelerometer, the microprocessor and the tri-axial accelerometer comprising a sensor device attached to a user, the sensor device further comprising memory, an actuator, and a power source;normalizing by the microprocessor the received accelerometer data;determining by the microprocessor a postural description of the user based on the normalized received accelerometer data, wherein the postural description comprises a current movement state and a current posture quality; andtriggering by the microprocessor the actuator to output sensory feedback based on the postural description of the user.2. The method of further comprising transmitting across a wireless electronic communication connection to a computing device the postural description of the user and the normalized received accelerometer data.3. (canceled)4. The method of wherein determining the postural description based on the normalized received accelerometer data comprises:computing feature vectors for the normalized received accelerometer data;quantizing the feature vectors;assigning the feature vectors to Gaussian distributions;acquiring distribution histograms for multiple movement states; andcomparing the distribution histograms to determine the current movement state from the multiple movement states.5. The method of wherein determining the postural description based on the normalized received accelerometer data comprises calculating a ...

System and method for detecting transitions between sitting and standing states

A system and method are described herein for detecting a user's transition between sitting and standing postures. Transitions between sitting and standing states are reliably detected using an accelerometer attached to the user. By modeling error introduced by the accelerometer, and correcting for this error, transitions between sitting and standing states are reliably detected. A microprocessor coupled to the accelerometer converts the captured accelerometer data to approximate vertical acceleration. Vertical velocity, which includes accelerometer error, is determined from the approximate vertical acceleration. The vertical velocity is corrected, and the corrected vertical velocity used to determine vertical displacement. Transitions between sitting and standing states are determined from the vertical displacement.

ADJUSTED STATIONARY AIRFOIL

A compressor component having an airfoil with a profile in accordance with Table 1 is disclosed. The compressor component, such as a compressor vane, has a decreased surface area over a portion of the airfoil chord length. The decreased surface area compressor vane operates in conjunction with a compressor blade having an increased surface area. 1. A compressor component having an attachment , a platform extending outward from the attachment and an airfoil extending radially outward from the platform , the airfoil having an uncoated profile substantially in accordance with Cartesian coordinate values of X and Z , for each distance Y in inches as set forth in Table 1 , carried to three decimal places , wherein Y is a distance measured radially outward from an engine centerline , the X and Z coordinate values being joined in smooth continuing splines to form airfoil sections and the airfoil sections joined smoothly to form the profile.2. The compressor component of claim 1 , wherein the airfoil has manufacturing tolerances of approximately +/−0.012 inches.3. The compressor component of claim 1 , wherein the airfoil has a root end proximate the attachment and a tip end spaced at opposite the root end.4. The compressor component of further comprising a squealer tip at the tip end.5. The compressor component of claim 1 , wherein the compressor component is a stationary vane.6. The compressor component of claim 5 , wherein the compressor component is located adjacent to rotor blades of a compressor.7. The compressor component of claim 1 , wherein the airfoil sections can be scaled uniformly in X claim 1 , Y claim 1 , and Z directions.8. An airfoil for a compressor vane claim 1 , the airfoil having an uncoated profile substantially in accordance with Cartesian coordinate values X claim 1 , Y claim 1 , and Z as set forth in Table 1 claim 1 , carried to three decimal places claim 1 , wherein Y is a distance measured in inches claim 1 , the X and Z coordinate values being ...

Adjusted rotating airfoil

A compressor component having an airfoil with a profile in accordance with Table 1 is disclosed. The compressor component, such as a compressor blade, has an increased surface area over a portion of the airfoil chord length. The increased surface area allows for a greater amount of air to be taken in by the airfoil, thus increasing the air flow through the gas turbine engine.

BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USES THEREOF

The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydrocodone (morphinan-6-one, 4,5-alpha-epoxy-3-methoxy-17-methyl) to form novel prodrugs/compositions of hydrocodone, including benzoates and heteroaryl carboxylic acids, which have a decreased potential for abuse of hydrocodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology. 168-. (canceled)70. The composition of claim 69 , wherein the conjugate is used to treat narcotic or opioid abuse; to reduce narcotic or opioid withdrawal; to treat moderate to severe pain; to reduce oral claim 69 , intranasal or intravenous drug abuse; or to provide oral intranasal or parenteral drug abuse resistance.71. The composition of claim 69 , wherein the composition exhibits an improved AUC and rate of release over time when compared to unconjugated hydrocodone over the same time period; exhibits less variability in the oral PK profile when compared to unconjugated hydrocodone; or has reduced side effects when compared with unconjugated hydrocodone.72. The composition of claim 71 , wherein the reduced side effects comprise reduced opioid induced constipation.73. The composition of claim 69 , wherein the composition is in a dosage form selected from the group consisting of: a tablet claim 69 , a capsule claim 69 , a caplet claim 69 , a soft gel claim 69 , a suppository claim 69 , a troche claim 69 , a lozenge claim 69 , an oral powder claim 69 , a solution claim 69 , an oral film claim 69 , a thin strip claim 69 , a slurry claim 69 , and a suspension.74. The composition of claim 73 , wherein the composition is in an amount sufficient to provide a therapeutically equivalent AUC when compared to unconjugated hydrocodone after oral administration.75. The composition of claim 73 , wherein the composition is in an amount sufficient to provide a therapeutically equivalent ...

Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydromorphone, Prodrugs, Methods of Making and Use Thereof

The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydromorphone (4,5-α-epoxy-3-hydroxy-17-methyl morphinan-6-one) to form novel prodrugs/compositions of hydromorphone. The hydromorphone prodrugs of the present technology have decreased side effects and decreased potential for abuse compared to unconjugated hydromorphone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology. 1120-. (canceled)121. A composition comprising at least one conjugate , wherein the at least one conjugate is 3-benzoate-hydromorphone.122. The composition of claim 121 , wherein the at least one conjugate is used to treat narcotic or opioid abuse; to prevent narcotic or opioid withdrawal; to treat moderate to severe pain; to reduce or prevent oral claim 121 , intranasal or intravenous drug abuse; or to provide oral claim 121 , intranasal or parenteral drug abuse resistance.123. The composition of claim 122 , wherein oral administration of the at least one conjugate results in an improved rate of release over time when compared to unconjugated hydromorphone over the same time period.124. The composition of claim 122 , wherein oral administration of the at least one conjugate results in less variability in the oral PK profile when compared to unconjugated hydromorphone.125. The composition of claim 122 , wherein oral administration of the at least one conjugate results in reduced side effects when compared with unconjugated hydromorphone.126. The composition of claim 125 , wherein the reduced side effect is reduced opioid induced constipation.127. The composition of claim 121 , wherein the at least one conjugate is provided in a dosage form selected from the group consisting of a tablet claim 121 , a capsule claim 121 , a caplet claim 121 , a suppository claim 121 , a troche claim 121 , a lozenge claim 121 , an oral powder claim 121 , a ...

BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF

The presently described technology provides compositions comprising aryl carboxylic acids and, for example NSAIDs, chemically conjugated to oxymorphone (4,5-α-epoxy-3,14-dihydroxy-17-methylmorphinan-6-one) to form novel prodrugs/compositions of oxymorphone, including benzoates, salicylates, propionates, fenamates, and acetates, which have a decreased potential for abuse of oxymorphone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology. 1. A composition comprising oxymorphone covalently attached to at least one carboxylic acid , a derivative thereof , a salt thereof , or a combination thereof.2. The composition of claim 1 , wherein the carboxylic acid is an aryl carboxylic acid.3. The composition of wherein the at least one aryl carboxylic acid is covalently attached to either the C-3 hydroxyl group of oxymorphone claim 2 , the C-6 enol tautomer of oxymorphone claim 2 , or the C-14 hydroxyl group of oxymorphone; or wherein at least two independently selected aryl carboxylic acids are attached to both the C-3 hydroxyl group and the C-6 enol tautomer of oxymorphone claim 2 , or the C-6 enol tautomer and C-14 hydroxyl group of oxymorphone claim 2 , or the C-3 hydroxyl group and C-14 hydroxyl group of oxymorphone; or wherein at least three independently selected aryl carboxylic acids are attached to the C-3 hydroxyl group claim 2 , C-6 enol tautomer and C-14 hydroxyl group of oxymorphone.5. The composition of claim 3 , wherein the aryl carboxylic acid is selected from the group consisting essentially of an aminobenzoate claim 3 , an analog of anthranilic acid claim 3 , fenamate claim 3 , hydroxybenzoate claim 3 , aminohydroxybenzoate claim 3 , salicylic acid analog claim 3 , or a derivative thereof.6. The composition of claim 3 , wherein said aryl carboxylic acid is selected from the group consisting essentially of benzoic acid claim 3 , salicylic acid claim 3 , ...

System and Method of Biomechanical Posture Detection and Feedback

A system and method are described herein for a sensor device which biomechanically detects in real-time a user's movement state and posture and then provides real-time feedback to the user based on the user's real-time posture. The feedback is provided through immediate sensory feedback through the sensor device (e.g., a sound or vibration) as well as through an avatar within an associated application with which the sensor device communicates. 1. A method of providing postural feedback comprising:receiving by a microprocessor at repeated intervals data from a tri-axial accelerometer, the microprocessor and the tri-axial accelerometer comprising a sensor device attached to a user, the sensor device further comprising memory, an actuator, and a power source;normalizing by the microprocessor the received accelerometer data;determining by the microprocessor a postural description of the user based on the normalized received accelerometer data; andtriggering by the microprocessor the actuator to output sensory feedback based on the postural description of the user.2. The method of further comprising transmitting across a wireless electronic communication connection to a computing device the postural description of the user and the normalized received accelerometer data.3. The method of wherein the postural description comprises a current movement state.4. The method of wherein determining the postural description based on the normalized received accelerometer data comprises:computing feature vectors for the normalized received accelerometer data;quantizing the feature vectors;assigning the feature vectors to Gaussian distributions;acquiring distribution histograms for multiple movement states; andcomparing the distribution histograms to determine the current movement state from the multiple movement states.5. The method of wherein determining the postural description based on the normalized received accelerometer data comprises calculating a pelvic tilt angle of the user ...

CONVEYOR SYSTEM WITH AUTOMATED CARRIERS

A conveyor system includes a fixed, non-powered rail defining a conveyor path. An automated conveyor carrier (ACC) is supported by the rail and drivable along the rail by an on-board motor in a self-driving trolley of the ACC, the motor powering a drive wheel. The rail defines a first section and a second section separate from the first section. The conveyor system is adapted to provide a first amount of traction for the ACC on the rail in the first section and a second amount of traction, greater than the first amount of traction, in the second section. 1. A conveyor system comprising:a fixed, non-powered rail defining a conveyor path; andan automated conveyor carrier (ACC) supported by the rail and drivable along the rail by an on-board motor in a self-driving trolley of the ACC, the motor powering a drive wheel,wherein the rail defines a first section and a second section separate from the first section, and wherein the conveyor system is adapted to provide a first amount of traction between the drive wheel of the ACC and the rail in the first section and to provide a second amount of traction, greater than the first amount of traction, between the drive wheel of the ACC and the rail in the second section.2. The conveyor system of claim 1 , wherein one or more springs are provided between a frame of the self-driving trolley and a frame that supports the motor relative to the self-driving trolley frame claim 1 , and the difference between the first and second amounts of traction in the first and second sections is the result of adjustment of the spring force in the one or more springs.3. The conveyor system of claim 2 , wherein the rail has a thicker web section in the second section as compared to the first section claim 2 , the change in web section automatically increasing the spring force.4. The conveyor system of claim 2 , further comprising an adjustment member between the self-driving trolley frame and the frame that supports the motor relative to the self- ...

CONVEYOR SYSTEM WITH AUTOMATED CARRIERS

A method of constructing a conveyor system includes decommissioning an existing conveyor system by removing electrification or a powered chain from a conveyor rail. Carriers of the existing conveyor system are removed from the rail. An automated conveyor carrier (ACC) is installed onto the rail so that a drive wheel of a self-driving trolley of the ACC is put into contact with the rail. A battery is installed on the ACC. Electrical connection is established from the battery to the self-driving trolley. 1. A method of constructing a conveyor system , the method comprising:decommissioning an existing conveyor system by removing electrification or a powered chain from a conveyor rail;removing carriers of the existing conveyor system from the rail;installing an automated conveyor carrier (ACC) onto the rail so that a drive wheel of a self-driving trolley of the ACC is put into contact with the rail;installing a battery on the ACC; andestablishing electrical connection from the battery to the self-driving trolley.2. The method of claim 1 , further comprising setting a load-carrying capacity of the ACC by adjusting a spring load within a spring that biases the drive wheel onto the rail.3. The method of claim 2 , wherein setting the load-carrying capacity of the ACC includes adjusting the spring load biasing an entire drive unit including both the drive wheel and a motor powering the drive wheel.4. The method of claim 2 , further comprising programming an on-board controller of the ACC with instructions for an actuator to further adjust the spring load biasing the drive wheel onto the rail in response to a detected position of the ACC along the rail.5. The method of claim 1 , wherein installing the ACC onto the rail includes installing at least one non-driving trolley of the ACC onto the rail.6. The method of claim 1 , further comprising programming an on-board controller of the ACC claim 1 , the controller including an inverter selectively powering an on-board motor of ...

CONVEYOR SYSTEM WITH AUTOMATED CARRIERS

A conveyorized industrial system includes at least one work station including a heated over chamber. A fixed, non-powered rail defines a conveyor path including an oven zone in which the rail extends through or over the heated oven chamber. An automated conveyor carrier (ACC) is suspended from the rail by a self-driving trolley having an on-board motor for driving the ACC along the rail, and by at least one additional free-rolling trolley. The ACC further comprises an enclosure containing one or both of an inverter and a battery, the enclosure having a wall defining an interior space of the enclosure. A heat protection system is provided in addition to the wall, the heat protection system operating to limit an internal temperature of the enclosure during transport along the oven zone. 1. A conveyorized industrial system comprising:at least one work station including a heated over chamber;a fixed, non-powered rail defining a conveyor path including an oven zone, wherein the rail extends through or over the heated oven chamber; andan automated conveyor carrier (ACC) including a self-driving trolley having an on-board motor, the ACC being suspended from the rail by the self-driving trolley and drivable along the rail by the self-driving trolley,wherein the ACC further comprises an enclosure containing one or both of an inverter and a battery, the enclosure having a wall defining an interior space of the enclosure, andwherein a heat protection system is provided in addition to the wall, the heat protection system operating to limit an internal temperature of the enclosure during transport along the oven zone.2. The conveyorized industrial system of claim 1 , wherein the heat protection system includes a heat shield coupled to an exterior surface of the enclosure at least at a bottom side of the enclosure.3. The conveyorized industrial system of claim 1 , wherein the heat protection system includes a layer of insulation within the wall of the enclosure.4. The ...

CONVEYOR SYSTEM WITH AUTOMATED CARRIERS

A method of operating a conveyor system includes providing a fixed, non-powered rail defining a conveyor path, the rail supporting first and second consecutive automated conveyor carriers (ACC), each of which includes a motor-powered self-driving trolley. First and second loads are suspended from the first and second ACCs. The first and second ACCs are driven independently along the rail by executing instructions from independent on-board controllers of the first and second ACCs, wherein a first spacing between the first and second ACCs is maintained through a first section of the rail. The first ACC is accelerated away from the second ACC to increase the spacing from the first spacing to a second spacing for navigating a second section of the rail, the second section being a curved section. 1. A method of operating a conveyor system , the method comprising:providing a fixed, non-powered rail defining a conveyor path, the rail supporting first and second consecutive automated conveyor carriers (ACC), each of which includes a motor-powered self-driving trolley;suspending a first load from the first ACC;suspending a second load from the second ACC;independently driving the first and second ACCs along the rail, wherein a first spacing between the first and second ACCs is maintained through a first section of the rail; andaccelerating the first ACC away from the second ACC to increase the spacing from the first spacing to a second spacing for navigating a second section of the rail, the second section being a curved section.2. The method of claim 1 , wherein the first ACC is accelerated away from the second ACC in the second section.3. The method of claim 1 , wherein the first ACC is accelerated away from the second ACC in the first section.4. The method of claim 1 , wherein the first spacing is a spacing that claim 1 , in combination with a radius of the second section claim 1 , would result in contact between the first and second loads within the second section.5. The ...

CONVEYOR SYSTEM WITH AUTOMATED CARRIERS

A method of operating a conveyor system includes providing a fixed, non-powered first rail supporting first and second trolleys of a first carrier, at least one of which is self-driving. The first and second trolley are conveyed in line along the first rail with a load bar therebetween. The first carrier defines a length measured along the first rail and a width measured transverse. The first carrier is conveyed to a branch point where a second rail branches from the first rail. The second trolley is conveyed along the second the rail to turn the first carrier so that it is conveyed with the load bar traversing between the first and second rails. The width is substantially less than the length such that the turning of the first carrier reduces an occupancy of the first carrier along the first rail. 1. A method of operating a conveyor system , the method comprising:providing a fixed, non-powered first rail defining a conveyor path, the first rail supporting first and second trolleys of a carrier, at least one of which is a self-driving trolley including an on-board motor and electrical power source;conveying the carrier under its own power such that the first and second trolleys are in line along the first rail with a load bar extended therebetween, the carrier defining a length measured along a longitudinal extent of the first rail and a width measured transverse to the longitudinal extent of the first rail, wherein the carrier is conveyed to a branch point where a second rail branches from the first rail; andconveying the first trolley along the first rail past the branch point and conveying the second trolley along the second the rail past the branch point to turn the carrier so that it is conveyed with the load bar extending transversely from the first rail to the second rail, wherein the width is substantially less than the length such that the turning of the carrier reduces an occupancy of the carrier along the first rail.2. The method of claim 1 , wherein the ...

CONVEYOR SYSTEM WITH AUTOMATED CARRIERS

A conveyor system including a fixed, non-powered rail defining a conveyor path, and a plurality of automated conveyor carriers supported on the rail. Each carrier includes an on-board motor and electrical power source selectively powering the motor to drive the carrier along the rail. Each of the plurality of ACCs operates to power the on-board motor from the on-board electrical power source under the direction of instructions programmed to a local controller on the respective ACC. Wherein each of the local controllers of the respective ACCs is programmed to carry out independent power level management for its own on-board electrical power source and configured to selectively operate an adaptive low power indicator to communicate a low power status based only in part on the power level of the on-board battery and further based on one or more parameters of a current work cycle. 1. A conveyor system comprising:a fixed, non-powered rail defining a conveyor path; anda plurality of automated conveyor carriers (ACC) supported on the rail to be movable along the conveyor path, each of the plurality of ACCs including an on-board motor and an on-board electrical power source selectively powering the on-board motor to drive the ACC along the rail, wherein each of the plurality of ACCs operates to power the on-board motor from the on-board electrical power source under the direction of instructions programmed to a local controller on the respective ACC,wherein each of the local controllers of the respective ACCs is programmed to carry out independent power level management for its own on-board electrical power source and configured to selectively operate an adaptive low power indicator to communicate a low power status based only in part on the power level of the on-board battery and further based on one or more parameters of a current work cycle.2. The conveyor system of claim 1 , wherein the adaptive low power indicator of each respective ACC is positioned in an observable ...

BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF

The presently described technology provides compositions comprising aryl carboxylic acids and, for example NSAIDs, chemically conjugated to oxycodone (4,5-α-epoxy-14-hydroxy-17-methylmorphinan-6-one) to form novel prodrugs/compositions of oxycodone, including benzoates, salicylates, propionates, fenamates, and acetates, which have a decreased potential for abuse of oxycodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology. 1. A composition comprising oxycodone covalently attached to at least one carboxylic acid , a derivative thereof , a salt thereof , or a combination thereof.2. The composition of claim 1 , wherein the carboxylic acid is an aryl carboxylic acid.3. The composition of claim 2 , wherein the aryl carboxylic acid is covalently attached to either the C-6 enol tautomer of oxycodone claim 2 , the C-14 hydroxyl group of oxycodone claim 2 , or an independently selected aryl carboxylic acid that is attached to both the C-6 enol tautomer and the C-14 hydroxyl group of oxycodone.5. The composition of claim 3 , wherein the aryl carboxylic acid is selected from the group consisting essentially of an aminobenzoate claim 3 , an analog of anthranilic acid claim 3 , fenamate claim 3 , hydroxybenzoate claim 3 , aminohydroxybenzoate claim 3 , salicylic acid analog claim 3 , or a derivative thereof.6. The composition of claim 3 , wherein said aryl carboxylic acid is selected from the group consisting essentially of benzoic acid claim 3 , salicylic acid claim 3 , acetylsalicylic acid (aspirin) claim 3 , 3-hydroxybenzoic acid claim 3 , 4-hydroxybenzoic acid claim 3 , 6-methylsalicylic acid claim 3 , o claim 3 ,m claim 3 ,p-cresotinic acid claim 3 , anacardic acids claim 3 , 4 claim 3 ,5-dimethylsalicylic acid claim 3 , o claim 3 ,m claim 3 ,p-thymotic acid claim 3 , diflusinal claim 3 , o claim 3 ,m claim 3 ,p-anisic acid claim 3 , 2 claim 3 ,3-dihydroxybenzoic acid (2 ...

Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Use Thereof

The presently described technology provides methods of treating a patient having moderate to severe pain, narcotic or opioid abuse or narcotic or opioid withdrawal. The presently described methods are carried out by comprising administering to the patient a pharmaceutically effective amount of a composition comprising acetaminophen and benzoate-hydrocodone hydrochloride. The composition has reduced side effects when compared with unconjugated hydrocodone. 1. A method of treating a patient having acute pain , comprising orally administering to the patient a pharmaceutically effective amount of a composition comprising benzhydrocodone and acetaminophen in an amount of 4.08 mg benzhydrocodone and 325 mg acetaminophen.2. The method of claim 1 , wherein the composition is in a tablet form.3. The method of claim 2 , wherein the tablet is an immediate release tablet.4. The method of claim 3 , wherein the tablet is administered as a dosage of 1 to 2 tablets every 4 to 6 hours.5. The method of claim 4 , wherein the dosage is up to 12 tablets in a 24 hour period.6. The method of claim 4 , wherein the dosage is up to 10 tablets in a 24 hour period.7. The method of claim 4 , wherein the dosage is up to 8 tablets in a 24 hour period.8. The method of claim 4 , wherein the dosage is up to 6 tablets in a 24 hour period.9. The method of claim 4 , wherein the dosage is up to 4 tablets in a 24 hour period.10. The method of claim 4 , wherein administration of the composition is for a period of time not exceeding 14 days.11. The method of claim 3 , wherein the tablet is contained in a blister pack or blister wallet pack.12. The method of claim 11 , wherein the blister pack or blister wallet pack comprises a child-resistant blister card.13. The method of claim 12 , wherein the child-resistant blister card is opened using a push-peel mechanism or peel-push mechanism.14. The method of claim 11 , wherein the blister pack or blister wallet pack contains up to 42 tablets.15. The method of ...

METHOD AND APPARATUS FOR DRAINING A WORK PIECE DURING FINISHING

A method of processing a work piece having an enclosure. The method comprises inserting a siphon into the enclosure, submerging the work piece in an immersion tank, removing the work piece from the tank, and draining liquid from the enclosure through the siphon. Inserting can include positioning at least a portion of a short leg of the siphon in the enclosure of the work piece. Preferably, draining includes directing liquid back into the immersion tank. After draining, the work piece can be moved to a second workstation and/or the siphon can be withdrawn from the enclosure. The method can be performed using a finishing system comprising a primary carrier, a work piece suspended from the primary carrier and defining an enclosure, and a siphon positioned in the enclosure. Preferably, the work piece is suspended above an immersion tank. The siphon can be positioned to direct fluid toward the immersion tank. 1. A method of processing a work piece having an enclosure through a workstation having an immersion tank with liquid , the method comprising:inserting a siphon at least partially into the enclosure of the work piece;submerging at least a portion of the work piece in the immersion tank to thereby cause the liquid in the immersion tank to at least partially fill the siphon and the enclosure in the work piece;removing the work piece from the immersion tank; anddraining liquid from the enclosure through the siphon.2. A method as claimed in claim 1 , wherein inserting includes attaching the siphon to the work piece.3. A method as claimed in claim 1 , wherein the siphon includes a short leg and a long leg claim 1 , and wherein inserting includes positioning at least a portion of the short leg in the enclosure of the work piece.4. A method as claimed in claim 1 , wherein submerging includes submerging the entire work piece in the liquid.5. A method as claimed in claim 1 , wherein removing includes lifting the work piece out of the immersion tank.6. A method as claimed in ...

Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Use Thereof

The presently described technology provides methods of treating a patient having moderate to severe pain, narcotic or opioid abuse or narcotic or opioid withdrawal. The presently described methods are carried out by comprising administering to the patient a pharmaceutically effective amount of a composition comprising acetaminophen and benzoate-hydrocodone hydrochloride. The composition has reduced side effects when compared with unconjugated hydrocodone. 1. A method of treating a patient having acute pain , comprising orally administering to the patient a pharmaceutically effective amount of a composition comprising benzhydrocodone and acetaminophen in an amount of 6.12 mg benzhydrocodone and 325 mg acetaminophen.2. The method of claim 1 , wherein the composition is in the form of a tablet.3. The method of claim 2 , wherein the tablet is an immediate release tablet.4. The method of claim 3 , wherein the tablet is administered as a dosage of 1 to 2 tablets every 4 to 6 hours.5. The method of claim 4 , wherein the dosage is up to 12 tablets in a 24 hour period.6. The method of claim 4 , wherein the dosage is up to 10 tablets in a 24 hour period.7. The method of claim 4 , wherein the dosage is up to 8 tablets in a 24 hour period.8. The method of claim 4 , wherein the dosage is up to 6 tablets in a 24 hour period.9. The method of claim 4 , wherein the dosage is up to 4 tablets in a 24 hour period.10. The method of claim 4 , wherein administration of the composition is for a period of time not exceeding 14 days.11. The method of claim 3 , wherein the tablet is contained in a blister pack.12. The method of claim 3 , wherein the benzhydrocodone is in the form of benzhydrocodone hydrochloride claim 3 , and wherein the 6.12 mg benzhydrocodone is equivalent to 6.67 mg benzhydrocodone hydrochloride.13. The method of claim 3 , wherein the 6.12 mg benzhydrocodone is equivalent to 4.54 mg hydrocodone.14. A method of treating a patient having pain claim 3 , comprising orally ...

Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Uses Thereof

The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydrocodone (morphinan-6-one, 4,5-alpha-epoxy-3-methoxy-17-methyl) to form novel prodrugs/compositions of hydrocodone, including benzoates and heteroaryl carboxylic acids, which have a decreased potential for abuse of hydrocodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology. 168-. (canceled)70. The composition of claim 69 , wherein the 13.34 mg benzoate-hydrocodone hydrochloride contains a molar equivalent of 9.08 mg of hydrocodone.71. The composition of claim 69 , wherein the conjugate results in the mean Cof hydrocodone of about 25 claim 69 ,600 pg/mL±6 claim 69 ,390 pg/mL when administered intranasally to a human.72. The composition of claim 69 , wherein the conjugate results in the mean Tof hydrocodone of about 2 hours±0.91 hours when administered intranasally to a human.73. The composition of claim 69 , wherein the conjugate results in the range of Tof hydrocodone from about 0.75 hours to about 4 hours when administered intranasally to a human.74. The composition of claim 69 , wherein the conjugate results in the mean AUCof hydrocodone of about 11.30 hours*pg/mL±14.14 hours*pg/mL when administered intranasally to a human.75. The composition of claim 69 , wherein the conjugate results in the mean AUCof hydrocodone of about 297.9 hours*pg/mL±170.3 hours*pg/mL when administered intranasally to a human.76. The composition of claim 69 , wherein the conjugate results in the mean AUCof hydrocodone of about 1 claim 69 ,485 hours*pg/mL±667.7 hours*pg/mL when administered intranasally to a human.77. The composition of claim 69 , wherein the conjugate results in the mean AUCof hydrocodone of about 3 claim 69 ,831 hours*pg/mL±1 claim 69 ,726 hours*pg/mL when administered intranasally to a human.78. The composition of claim 69 , wherein the conjugate ...

INDUSTRIAL OVEN WITH FABRIC DUCT

An industrial oven includes an oven chamber configured to receive a plurality of work pieces. A heater box of the oven has a heating element therein operable to heat air for delivery to the oven chamber. A circulation system of the oven is operable to force hot air from the heater box into the oven chamber. The circulation system includes a delivery manifold extending from the heater box to the oven chamber. A duct has an inlet coupled with an outlet of the delivery manifold, and the duct has a plurality of hot air outlet apertures therein for expelling hot air into the oven chamber. The duct is constructed of fabric sheet and suspended within the oven chamber. 1. An industrial oven comprising:an oven chamber configured to receive a plurality of work pieces;a heater box having a heating element therein operable to heat air for delivery to the oven chamber; anda circulation system operable to force hot air from the heater box into the oven chamber, the circulation system including a delivery manifold extending from the heater box to the oven chamber, and a duct having an inlet coupled with an outlet of the delivery manifold, the duct having a plurality of hot air outlet apertures therein for expelling hot air into the oven chamber,wherein the duct is constructed of fabric sheet and suspended within the oven chamber.2. The industrial oven of claim 1 , further comprising a conveyor system including a conveyor rail extending through the oven chamber claim 1 , wherein a conveyance plane is defined to extend vertically below the conveyor rail between an inlet and an outlet of the oven chamber.3. The industrial oven of claim 2 , wherein the duct extends alongside the conveyor rail claim 2 , and the plurality of hot air outlet apertures are directed laterally toward the conveyance plane.4. The industrial oven of claim 3 , wherein the duct is a first duct extending along a first lateral side of the conveyor rail claim 3 , the circulation system further comprising a second ...

SYSTEM AND METHOD FOR SENSING AND RESPONDING TO FATIGUE DURING A PHYSICAL ACTIVITY

A system and method for utilizing an activity monitoring device that includes, during a set of initial activity sessions, collecting the kinematic data from an activity monitoring device and generating a temporal record of at least one biomechanical signal that is calculated from the kinematic data; analyzing temporal changes in the biomechanical signals during the initial activity sessions and characterizing a fatigue model; and, during a subsequent activity session collecting current kinematic data of a participant and generating at least one current biomechanical signal from the current kinematic data, monitoring the fatigue state through processing the at least one current biomechanical signal according to the fatigue model, and triggering feedback in a user interface based on the fatigue state. 1. A method for utilizing an activity monitoring device comprising:setting a fatigue model; and collecting current kinematic data of a participant and generating at least one current biomechanical signal from the current kinematic data,', 'monitoring a fatigue state through processing the at least one current biomechanical signal according to the fatigue model, and', 'triggering feedback in a user interface based on the fatigue state., 'during an activity session2. The method of claim 1 , wherein the at least one current biomechanical signal includes ground contact time of a running activity.3. The method of claim 2 , wherein processing the at least one current biomechanical signal according to the fatigue mode comprises verifying that the current ground contact time is above a base threshold and verifying that variance of the current ground contact time is above a variance threshold.4. The method of claim 1 , wherein setting the fatigue model comprises:during a set of initial activity sessions, collecting the kinematic data from an activity monitoring device and generating a temporal record of at least one biomechanical signal that is calculated from the kinematic data; ...

SYSTEM AND METHOD OF BIOMECHANICAL POSTURE DETECTION AND FEEDBACK

A system and method are described herein for a sensor device which biomechanically detects in real-time a user's movement state and posture and then provides real-time feedback to the user based on the user's real-time posture. The feedback is provided through immediate sensory feedback through the sensor device (e.g., a sound or vibration) as well as through an avatar within an associated application with which the sensor device communicates. 1. A method of providing postural feedback comprising:receiving by a microprocessor data from a tri-axial accelerometer, the microprocessor and the tri-axial accelerometer comprising a sensor device attached to a user, the sensor device further comprising an actuator;normalizing by the microprocessor the received accelerometer data; computing a sequence of accelerometer data features from the normalized received accelerometer data,', 'analyzing the sequence of accelerometer data features according to a rule-based model to determine, in part, the postural description; and, 'determining by the microprocessor a postural description of the user based on the normalized received accelerometer data, wherein the postural description comprises a movement state, wherein determining the postural description of the user comprisestriggering by the microprocessor the actuator to output sensory feedback based on the postural description of the user.2. A non-transitory computer readable medium having stored thereupon computing instructions comprising:a code segment to receive by a microprocessor at repeated intervals data from a tri-axial accelerometer, the microprocessor and the tri-axial accelerometer comprising a sensor device attached to a user, the sensor device further comprising an actuator;a code segment to normalize by the microprocessor the received accelerometer data; a code segment to compute a sequence of accelerometer data features from the normalized received accelerometer data,', 'a code segment to analyze the sequence of ...

Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Uses Thereof

The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydrocodone (morphinan-6-one, 4,5-alpha-epoxy-3-methoxy-17-methyl) to form novel prodrugs/compositions of hydrocodone, including benzoates and heteroaryl carboxylic acids, which have a decreased potential for abuse of hydrocodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology. 2. The composition of claim 1 , wherein the 13.34 mg benzoate-hydrocodone hydrochloride contains a molar equivalent of 9.08 mg of hydrocodone.3. The composition of claim 1 , wherein the conjugate results in the mean Cof hydrocodone of about 25 claim 1 ,600 pg/mL±6 claim 1 ,390 pg/mL when administered intranasally to a human.4. The composition of claim 1 , wherein the conjugate results in the mean Tof hydrocodone of about 2 hours±0.91 hours when administered intranasally to a human.5. The composition of claim 1 , wherein the conjugate results in the range of Tof hydrocodone from about 0.75 hours to about 4 hours when administered intranasally to a human.6. The composition of claim 1 , wherein the conjugate results in the mean AUCof hydrocodone of about 11.30 hours*pg/mL±14.14 hours*pg/mL when administered intranasally to a human.7. The composition of claim 1 , wherein the conjugate results in the mean AUCof hydrocodone of about 297.9 hours*pg/mL±170.3 hours*pg/mL when administered intranasally to a human.8. The composition of claim 1 , wherein the conjugate results in the mean AUCof hydrocodone of about 1 claim 1 ,485 hours*pg/mL±667.7 hours*pg/mL when administered intranasally to a human.9. The composition of claim 1 , wherein the conjugate results in the mean AUCof hydrocodone of about 3 claim 1 ,831 hours*pg/mL±1 claim 1 ,726 hours*pg/mL when administered intranasally to a human.10. The composition of claim 1 , wherein the conjugate results in the mean AUCof hydrocodone of ...

TILTING MULTIPLIER

A tilting carrier assembly for a finishing process includes a load bar configured to convey a work piece relative to a work station. A skid is configured to receive the work piece. Each of a pair of links is pivotally coupled to the load bar at a first end and pivotally coupled to the skid at an opposite second end. A horizontal span between the first ends of the pair of links is substantially greater than a horizontal span between the second ends of the pair of links. 1. A method of operating a tilting carrier assembly , the method comprising:operating a conveyor in a primary direction of travel;conveying a work piece with a load bar along the primary direction of travel relative to a work station, wherein the load bar is coupled to the conveyor with first and second couplings that are laterally spaced transverse to the primary direction of travel;providing a skid configured to receive the work piece;providing a pair of links, each of the links being pivotally coupled to the load bar at a first end and pivotally coupled to the skid at an opposite second end; andtilting the load bar to a first angle relative to horizontal; andin response to tilting the load bar to the first angle, tilting of the skid to a second angle relative to horizontal, the second angle being greater than the first angle.2. The method of claim 1 , wherein the pair of links is configured so that tilting of the load bar to a first angle relative to horizontal results in tilting of the skid to a second angle relative to horizontal claim 1 , the second angle being at least 50 percent greater than the first angle.3. The method of claim 1 , wherein the pair of links is configured so that tilting of the load bar to a first angle relative to horizontal results in tilting of the skid to a second angle relative to horizontal claim 1 , the second angle being at least twice the first angle.4. The method of claim 1 , wherein the pair of links is configured so that tilting of the load bar to a first angle ...

SYSTEM AND METHOD OF COATING PRODUCTS

Systems and methods are provided for coating interior surfaces of products with coating material. The systems and methods can include at least one plug to selectively close an opening of the product, wherein the plug is movable relative to the opening between a first position in which the plug is retracted from the opening and a second position in which the plug is engaged with the opening to seal the opening. When the plug is in the second position, a pump delivers coating material to the cavity of the product via a fluid line and a port in the plug. The coating material can fill the cavity, and an electrode can be energized to coat the interior surface of the product with an electrophoretic deposition process. Other coating processes can also be used in a similar manner. 1. A product coating system for coating a product with a coating material , the product including an exterior surface , a cavity defined by an interior surface , and an opening extending between the exterior surface and the interior surface , the product coating system comprising:a plug sized and shaped to selectively close the opening, the plug movable relative to the opening between a first position in which the plug is retracted from the opening, and a second position in which the plug is engaged with the opening to close the opening;a port defined in the plug and through which the coating material passes to enter the cavity;a pump; anda fluid line establishing fluid communication between the pump and the port;the system having a first configuration in which the plug is in the first position and coating material delivery to the cavity is stopped, and a second configuration in which the plug is in the second position and in which the pump delivers coating material to the cavity of the product via the fluid line and port.2. The product coating system of claim 1 , wherein the plug establishes a liquid-tight seal with respect to the product when the plug is in the second position.3. The product ...

Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Uses Thereof

The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydrocodone (morphinan-6-one, 4,5-alpha-epoxy-3-methoxy-17-methyl) to form novel prodrugs/compositions of hydrocodone, including benzoates and heteroaryl carboxylic acids, which have a decreased potential for abuse of hydrocodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology. 175-. (canceled)77. The compound of claim 76 , wherein the salt is a pharmaceutically acceptable salt.78. The compound of claim 77 , wherein the salt is selected from the group consisting of acetate claim 77 , L-aspartate claim 77 , besylate claim 77 , bicarbonate claim 77 , carbonate claim 77 , D-camsylate claim 77 , L-camsylate claim 77 , citrate claim 77 , edisylate claim 77 , fumarate claim 77 , gluconate claim 77 , hydrobromide/bromide claim 77 , hydrochloride/chloride claim 77 , D-lactate claim 77 , L-lactate claim 77 , D claim 77 ,L-lactate claim 77 , D claim 77 ,L-malate claim 77 , L-malate claim 77 , mesylate claim 77 , pamoate claim 77 , phosphate claim 77 , succinate claim 77 , sulfate claim 77 , D-tartrate claim 77 , L-tartrate claim 77 , D claim 77 ,L-tartrate claim 77 , meso-tartrate claim 77 , benzoate claim 77 , gluceptate claim 77 , D-glucuronate claim 77 , hybenzate claim 77 , isethionate claim 77 , malonate claim 77 , methylsulfate claim 77 , 2-napsylate claim 77 , nicotinate claim 77 , nitrate claim 77 , orotate claim 77 , stearate claim 77 , tosylate claim 77 , acefyllinate claim 77 , aceturate claim 77 , aminosalicylate claim 77 , ascorbate claim 77 , borate claim 77 , butyrate claim 77 , camphorate claim 77 , camphocarbonate claim 77 , decanoate claim 77 , hexanoate claim 77 , cholate claim 77 , cypionate claim 77 , dichloroacetate claim 77 , edentate claim 77 , ethyl sulfate claim 77 , furate claim 77 , fusidate claim 77 , galactarate (mucate) claim 77 ...

Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydromorphone, Prodrugs, Methods of Making and Use Thereof

The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydromorphone (4,5-α-epoxy-3-hydroxy-17-methyl morphinan-6-one) to form novel prodrugs/compositions of hydromorphone. The hydromorphone prodrugs of the present technology have decreased side effects and decreased potential for abuse compared to unconjugated hydromorphone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology. 1. A prodrug composition comprising at least one conjugate , wherein the at least one conjugate is 3-aspirin-hydromorphone.2. The prodrug composition of claim 1 , wherein the at least one conjugate is used to treat narcotic or opioid abuse; to prevent narcotic or opioid withdrawal; to treat moderate to severe pain; to reduce or prevent oral claim 1 , intranasal or intravenous drug abuse; or to provide oral claim 1 , intranasal or parenteral drug abuse resistance.2. The prodrug composition of claim 1 , wherein oral administration of the at least one conjugate results in an improved AUC and rate of release over time when compared to unconjugated hydromorphone over the same time period.4. The prodrug composition of claim 1 , wherein oral administration of the at least one conjugate results in less variability in the oral PK profile when compared to unconjugated hydromorphone.5. The prodrug composition of claim 1 , wherein oral administration of the at least one conjugate results in reduced side effects when compared with unconjugated hydromorphone.6. The prodrug composition of claim 5 , wherein the reduced side effect is reduced opioid induced constipation.7. The prodrug composition of claim 1 , wherein at least one conjugate is provided in a dosage form selected from the group consisting of a tablet claim 1 , a capsule claim 1 , a caplet claim 1 , a suppository claim 1 , a troche claim 1 , a lozenge claim 1 , an oral powder claim 1 , a ...

SYSTEM AND METHOD WITH MULTI-AXIS TILTING

A system includes a plurality of stations positioned along a direction of conveyance. Rails span the length of all stations and include at least first, second, and third rails configured for independent vertical movement. A plurality of objects is supported by and movable along the first, second, and third rails between the stations. Each of the plurality of objects has first, second, and third supports coupled to the respective first, second, and third rails so that all of the plurality of objects tilt in unison about a first set of parallel axes in response to the first, second, and third rails being positioned in a first configuration of vertical heights, and all of the plurality of objects tilt in unison about a second set of parallel axes in response to the first, second, and third rails being positioned in a second configuration of vertical heights. 1. A system comprising:a plurality of stations positioned along a direction of conveyance;a set of rails spanning across a length of the plurality of stations and including at least first, second, and third rails configured for independent vertical movement; anda plurality of objects supported by and movable along the first, second, and third rails relative to the plurality of stations so that each of the plurality of objects can be positioned at a corresponding one of the stations,wherein each of the plurality of objects has first, second, and third supports coupled to the respective first, second, and third rails so that all of the plurality of objects tilt in unison about a first set of axes in response to the first, second, and third rails being positioned in a first configuration of relative vertical heights, and all of the plurality of objects tilt in unison about a second set of axes in response to the first, second, and third rails being positioned in a second configuration of relative vertical heights different than the first configuration.2. The system of claim 1 , wherein the plurality of stations ...

System and Method for Calculating Remaining Useful Time of Objects

An aspect of the present invention is to provide a system and method for predicting the remaining useful time of mechanical components such as bearings. Another aspect of the present invention is to provide a system and method for predicting the remaining useful time of bearings based on available condition monitoring data. Another aspect of the present invention is to provide a system and method for automatically deciding which columns of input information are the most significant for predicting the remaining useful life of bearings. Another aspect of the present invention is to provide a system and method for performing an analysis of both test bearings and training bearings and determining which training bearings are most similar to a given test bearing. Another aspect of the present invention is to provide a system and method for training an artificial neural network. 1. A computer implemented method of generating a used life percentage that is capable of identifying the remaining life in a mechanical component such as a bearing , comprising:obtaining sensor data from the mechanical component and organizing the obtained sensor data into a defined matrix;calculating correlation coefficients for each matrix column and ranking the columns according to the correlation coefficients;inputting the ranked columns into a series of corresponding artificial neural networks and training each artificial neural network with its corresponding column;identifying the remaining useful life based on the trained artificial neural networks;2. The method of claim 1 , wherein the correlation coefficients are calculated for each column by determining a moving average of vibration signals and time;3. The method of claim 1 , wherein the identifying the remaining useful life further comprises:calculating a prediction error for each artificial neural network and ranking the artificial neural networks based on their error;combining the results of all ANN predictions into a combination ...

System and method of biomechanical posture detection and feedback including sensor normalization

A system and method are described herein for a sensor device which biomechanically detects in real-time a user's movement state and posture and then provides real-time feedback to the user based on the user's real-time posture. The feedback is provided through immediate sensory feedback through the sensor device (e.g., a sound or vibration) as well as through an avatar within an associated application with which the sensor device communicates. The sensor device detects the user's movement state and posture by capturing data from a tri-axial accelerometer in the sensor device. Streamed data from the accelerometer is normalized to correct for sensor errors as well as variations in sensor placement and orientation. Normalization is based on accelerometer data collected while the user is wearing the device and performing specific actions. 1. (canceled)2. (canceled)3. A method comprising:capturing, by a accelerometer attached to a user, first set of accelerometer data over a first period of time while the user is in a first movement state;averaging the captured first accelerometer data and creating a first normalization matrix;capturing, by the accelerometer attached to the user, second set of accelerometer data over a second period of time, while the user is in a second movement state;averaging the captured second accelerometer data and creating a second normalization matrix;capturing, by the accelerometer attached to the user, third accelerometer data at a third point in time;creating, by the microprocessor, normalized accelerometer data by applying the first normalization matrix and the second normalization matrix to the captured third accelerometer data; andanalyzing at least the normalized accelerometer data and determining a current movement state.4. The method of claim 3 , further comprising determining a posture quality during a walking movement state claim 3 , which comprises determining an average tilt angle from the normalized accelerometer data.5. The method ...

SYSTEM AND METHOD FOR AUTOMATIC POSTURE CALIBRATION

A system and method for posture feedback can include collecting kinematic data by an activity monitoring device coupled to a user; calibrating the kinematic data to a base walking orientation of the activity monitoring device, which comprises: detecting a walking activity state through the kinematic data, and when a walking activity state is detected, generating the base walking orientation from kinematic data; setting a posture correction factor; measuring user posture with the calibrated kinematic data; triggering posture feedback based on the user posture adjusted by the posture correction factor.

PHARMACEUTICALLY ACCEPTABLE SALTS AND POLYMORPHIC FORMS OF HYDROCODONE BENZOIC ACID ENOL ESTER AND PROCESSES FOR MAKING SAME

Compositions comprising hydrocodone benzoic acid enol ester to form novel prodrugs including hydrocodone benzoic acid enol ester salts, and various polymorphs. Also provided are processes for the preparation of hydrocodone benzoic acid enol ester salts, and various polymorphs. 183-. (canceled)84. A process for the preparation of benzhydrocodone enol ester comprising the steps of:(a) preparing a mixture comprising hydrocodone free base and a benzoylating reagent, and,(b) heating the mixture to a temperature in the range of about 80° C. to about 160° C.85. The process of claim 84 , wherein the benzoylating reagent is selected from the group consisting of benzoic anhydride or benzoyl chloride.86. The process of claim 84 , wherein the mixture further comprises a suitable organic solvent.87. The process of claim 86 , wherein the suitable organic solvent is selected from the group consisting of toluene claim 86 , dimethylformamide claim 86 , N-methyl-2-pyrrolidinone claim 86 , and xylenes.88. The process of claim 87 , wherein the suitable organic solvent is toluene.89. A process for the preparation of benzhydrocodone comprising the steps of:(a) preparing a mixture comprising hydrocodone free base, benzoic anhydride, and toluene and,(b) heating the mixture to a temperature in the range of about 80° C. to about 160° C.90. The process of or claim 87 , wherein the toluene is substantially removed from the mixture via step b.91. The process of claim 87 , claim 87 , or claim 87 , wherein the temperature of step (b) is in the range of about 126° C. to about 132° C.92. The process of claim 87 , claim 87 , or wherein the mixture further comprises a suitable base.93. The process of claim 92 , wherein the suitable base is selected from the group consisting of pyridine claim 92 , N claim 92 ,N-diisopropylethylamine claim 92 , diazabicycloundecene claim 92 , trimethylamine claim 92 , and potassium benzoate.94. The process of claim 92 , claim 92 , or further comprising adding ...

SYSTEM AND METHOD FOR DETECTING TRANSITIONS BETWEEN SITTING AND STANDING STATES

A system and method are described herein for detecting a user's transition between sitting and standing postures. Transitions between sitting and standing states are reliably detected using an accelerometer attached to the user. By modeling error introduced by the accelerometer, and correcting for this error, transitions between sitting and standing states are reliably detected. A microprocessor coupled to the accelerometer converts the captured accelerometer data to approximate vertical acceleration. Vertical velocity, which includes accelerometer error, is determined from the approximate vertical acceleration. The vertical velocity is corrected, and the corrected vertical velocity used to determine vertical displacement. Transitions between sitting and standing states are determined from the vertical displacement. 1. A method of detecting a user transition between sitting and standing states comprising:capturing, by a tri-axial accelerometer attached to a user, a plurality of points of accelerometer data over a period of time,determining, by a microprocessor, a plurality of points of approximate vertical acceleration due to user motion from the plurality of points of accelerometer data,determining, by the microprocessor, a plurality of points of vertical velocity from the plurality of points of approximate vertical acceleration due to user motion,segmenting, by the microprocessor, the plurality of points of vertical velocity,correcting, by the microprocessor, each of the segments of points of vertical velocity,determining, by the microprocessor, a segment of points of vertical displacement for each corrected segment of points of vertical velocity, anddetecting, by the microprocessor, a user transition between sitting and standing states from the segments of points of vertical displacement.2. The method of where determining the plurality of points of approximate vertical acceleration due to user motion from the plurality of points of accelerometer data comprises: ...

SYSTEMS AND METHODS FOR USING COGNITIVE FINGERPRINTS

A system and method for creating a core cognitive fingerprint. A core cognitive fingerprint can be used to capture the evolution of a system state and potentially respond with a predetermined action if the fingerprint falls within a threshold. The method includes: identifying a set of time frames within which data is extracted; providing a plurality of pattern recognizers; processing the extracted data through the plurality of pattern recognizers to generate an initial set of elements; extracting identified relationships amongst the initial set of elements; modifying the initial set of elements to include the identified relationships to create an intermediate set of elements; comparing the intermediate set of elements against assigned values to weigh each element in the intermediate set of elements to create a final set of elements; and using the final set of elements as a cognitive fingerprint. 1. A computer implemented method of constructing a cognitive fingerprint , comprising:identifying a set of time frames, each time frame corresponding to a respective data source, within which data is extracted from the data source by a computer system;providing a plurality of pattern recognizers each having an assigned heuristic;processing, by the computer system, a combined stream of extracted data through the plurality of pattern recognizers to generate an initial set of elements, each element corresponding to the output of the heuristic assigned to each pattern recognizer;extracting identified relationships amongst the initial set of elements;modifying the initial set of elements to include the identified relationships to create an intermediate set of elements;comparing, by the computer system, the intermediate set of elements against assigned weight values to emphasize or deemphasize each element in the intermediate set of elements to create a final set of elements; andusing the final set of elements as a cognitive fingerprint representing a signature of the data ...

PHARMACEUTICALLY ACCEPTABLE SALTS AND POLYMORPHIC FORMS OF HYDROCODONE BENZOIC ACID ENOL ESTER AND PROCESSES FOR MAKING SAME

Compositions comprising hydrocodone benzoic acid enol ester to form novel prodrugs including hydrocodone benzoic acid enol ester salts, and various polymorphs. Also provided are processes for the preparation of hydrocodone benzoic acid enol ester salts, and various polymorphs. 183-. (canceled)84. A process for the preparation of hydrocodone benzoic acid enol ester comprising the steps of:(a) preparing a mixture comprising hydrocodone free base and a benzoylating reagent, and,(b) heating the mixture to a temperature in the range of about 80° C. to about 160° C.85. The process of claim 84 , wherein the benzoylating reagent is selected from the group consisting of benzoic anhydride or benzoyl chloride.86. The process of claim 84 , wherein the mixture further comprises a suitable organic solvent.87. The process of claim 86 , wherein the suitable organic solvent is selected from the group consisting of toluene claim 86 , dimethylformamide claim 86 , N-methyl-2-pyrrolidinone claim 86 , and xylenes.88. The process of claim 87 , wherein the suitable organic solvent is toluene.89. A process for the preparation of benzhydrocodone comprising the steps of:(a) preparing a mixture comprising hydrocodone free base, benzoic anhydride, and toluene and,(b) heating the mixture to a temperature in the range of about 80° C. to about 160° C.90. The process of claim 88 , wherein the toluene is substantially removed from the mixture via step b.91. The process of wherein the temperature of step (b) is in the range of about 126° C. to about 132° C.92. The process of claim 84 , wherein the mixture further comprises a suitable base.93. The process of claim 92 , wherein the suitable base is selected from the group consisting of pyridine claim 92 , N claim 92 ,N-diisopropylethylamine claim 92 , diazabicycloundecene claim 92 , trimethylamine claim 92 , and potassium benzoate.94. The process of claim 84 , further comprising adding concentrated hydrochloric acid to the mixture.95. A pharmaceutical ...

BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF

The presently described technology provides compositions comprising aryl carboxylic acids and, for example NSAIDs, chemically conjugated to oxymorphone (4,5-α-epoxy-3,14-dihydroxy-17-methylmorphinan-6-one) to form novel prodrugs/compositions of oxymorphone, including benzoates, salicylates, propionates, fenamates, and acetates, which have a decreased potential for abuse of oxymorphone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology. 1. A composition comprising oxymorphone covalently attached to at least one carboxylic acid , a derivative thereof , a salt thereof , or a combination thereof.2. The composition of claim 1 , wherein the carboxylic acid is an aryl carboxylic acid.3. The composition of wherein the at least one aryl carboxylic acid is covalently attached to either the C-3 hydroxyl group of oxymorphone claim 2 , the C-6 enol tautomer of oxymorphone claim 2 , or the C-14 hydroxyl group of oxymorphone; or wherein at least two independently selected aryl carboxylic acids are attached to both the C-3 hydroxyl group and the C-6 enol tautomer of oxymorphone claim 2 , or the C-6 enol tautomer and C-14 hydroxyl group of oxymorphone claim 2 , or the C-3 hydroxyl group and C-14 hydroxyl group of oxymorphone; or wherein at least three independently selected aryl carboxylic acids are attached to the C-3 hydroxyl group claim 2 , C-6 enol tautomer and C-14 hydroxyl group of oxymorphone.5. The composition of claim 3 , wherein the aryl carboxylic acid is selected from the group consisting essentially of an aminobenzoate claim 3 , an analog of anthranilic acid claim 3 , fenamate claim 3 , hydroxybenzoate claim 3 , aminohydroxybenzoate claim 3 , salicylic acid analog claim 3 , or a derivative thereof.6. The composition of claim 3 , wherein said aryl carboxylic acid is selected from the group consisting essentially of benzoic acid claim 3 , salicylic acid claim 3 , ...

Conveyor system with automated carriers

A conveyor system comprising a fixed, non-powered rail defining a conveyor path and an automated conveyor carrier (ACC) supported on the rail to be movable along the conveyor path. The ACC includes an on-board motor and an on-board electrical power source selectively powering the on-board motor to drive the ACC along the rail. The ACC may include a wireless sleep mode module operable to selectively shut off power to an on-board ACC controller.

System and Method of Biomechanical Posture Detection and Feedback Including Sensor Normalization

A system and method are described herein for a sensor device which biomechanically detects in real-time a user's movement state and posture and then provides real-time feedback to the user based on the user's real-time posture. The feedback is provided through immediate sensory feedback through the sensor device (e.g., a sound or vibration) as well as through an avatar within an associated application with which the sensor device communicates. The sensor device detects the user's movement state and posture by capturing data from a tri-axial accelerometer in the sensor device. Streamed data from the accelerometer is normalized to correct for sensor errors as well as variations in sensor placement and orientation. Normalization is based on accelerometer data collected while the user is wearing the device and performing specific actions.

Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Use Thereof

The presently described technology provides methods of treating a patient having moderate to severe pain, narcotic or opioid abuse or narcotic or opioid withdrawal. The presently described methods are carried out by comprising administering to the patient a pharmaceutically effective amount of a composition comprising acetaminophen and benzoate-hydrocodone hydrochloride. The composition has reduced side effects when compared with unconjugated hydrocodone. 1. A method for treating a patient having moderate to severe pain , narcotic or opioid abuse or narcotic or opioid withdrawal comprising administering to the patient a pharmaceutically effective amount of a composition comprising acetaminophen and benzoate-hydrocodone hydrochloride wherein the composition has reduced side effects when compared with unconjugated hydrocodone.2. The method of claim 1 , wherein the composition comprises benzoate-hydrocodone hydrochloride and acetaminophen having a molar ratio from 0.001: 1 to 1000:1.3. The method of claim 1 , wherein the composition is a conjugate.4. The method of claim 1 , wherein the composition is a prodrug.5. The method of claim 1 , wherein the composition is used to reduce or prevent oral claim 1 , intranasal or intravenous drug abuse; or to provide oral claim 1 , intranasal or parenteral drug abuse resistance.6. The method of claim 1 , wherein the composition exhibits an improved AUC and rate of release of hydrocodone over time when compared to unconjugated hydrocodone over the same time period; exhibits lower exposure to hydrocodone at about more than 53 mg when compared to an equivalent molar amount of unconjugated hydrocodone.7. The method of claim 1 , wherein the composition exhibits an improved AUC and rate of release of hydromorphone over time when compared to unconjugated hydrocodone over the same time period; exhibits lower exposure to hydromorphone at about more than 53 mg when compared to an equivalent molar amount of unconjugated hydrocodone.8. The ...

TILTING MULTIPLIER

A method of operating a tilting carrier assembly includes operating a conveyor in a primary direction of travel and supporting a work piece from the conveyor by a pair of links. A pair of respective upper connection points of the links are laterally spaced transverse to the primary direction of travel and a pair of respective lower connection points of the links are also laterally spaced. The work piece is conveyed along the primary direction of travel relative to a work station, and the upper connection points are tilted so that a line therebetween forms a first angle relative to horizontal. In response, the lower connection points and the work piece are tilted to a second angle relative to horizontal, and the second angle is greater than the first angle. 1. A method of operating a tilting carrier assembly , the method comprising:operating a conveyor in a primary direction of travel;supporting a work piece from the conveyor by a pair of links, wherein a pair of respective upper connection points of the pair of links are laterally spaced transverse to the primary direction of travel and a pair of respective lower connection points of the pair of links are laterally spaced transverse to the primary direction of travel;conveying the work piece along the primary direction of travel relative to a work station;tilting the upper connection points so that a line therebetween forms a first angle relative to horizontal; andin response to the tilting of the upper connection points to form the first angle, tilting the lower connection points and the work piece to a second angle relative to horizontal, the second angle being greater than the first angle.2. The method of claim 1 , wherein the second angle is at least 50 percent greater than the first angle.3. The method of claim 1 , wherein the second angle is at least twice the first angle.4. The method of claim 1 , wherein the second angle is about 2.5 times the first angle.5. The method of claim 1 , wherein the lower ...

BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF

The presently described technology provides compositions comprising aryl carboxylic acids and, for example NSAIDs, chemically conjugated to oxymorphone (4,5-α-epoxy-3,14-dihydroxy-17-methylmorphinan-6-one) to form novel prodrugs/compositions of oxymorphone, including benzoates, salicylates, propionates, fenamates, and acetates, which have a decreased potential for abuse of oxymorphone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology. 2. A composition comprising a conjugate claim 1 , wherein the conjugate is the compound of claim 1 , a salt thereof claim 1 , or a combination thereof.3. The composition of claim 2 , wherein the composition is in a dosage form selected from the group consisting of a tablet claim 2 , a capsule claim 2 , a caplet claim 2 , a soft gel claim 2 , a suppository claim 2 , a troche claim 2 , a lozenge claim 2 , an oral powder claim 2 , a solution claim 2 , an oral film claim 2 , a thin strip claim 2 , a slurry claim 2 , and a suspension.4. The composition of claim 2 , wherein the composition is in an amount sufficient to provide a therapeutically equivalent AUC when compared to unconjugated oxymorphone when administered orally.5. The composition of claim 2 , wherein the composition is in an amount sufficient to provide a therapeutically equivalent AUC and Cwhen compared to an equivalent molar amount of unconjugated oxymorphone when administered orally.6. The composition of claim 2 , wherein the composition is in an amount sufficient to provide a therapeutically equivalent AUC and a lower Cwhen compared to an equivalent molar amount of unconjugated oxymorphone when administered orally.7. The composition of claim 2 , wherein intranasal or intravenous administration of the compound provides a lower AUC and/or Cmax when compared to an equivalent molar amount of unconjugated oxymorphone.8. The composition of claim 2 , wherein oral administration ...

Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydromorphone, Prodrugs, Methods of Making and Use Thereof

The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydromorphone (4,5-α-epoxy-3-hydroxy-17-methyl morphinan-6-one) to form novel prodrugs/compositions of hydromorphone. The hydromorphone prodrugs of the present technology have decreased side effects and decreased potential for abuse compared to unconjugated hydromorphone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology. 1. A composition comprising a hydromorphone conjugate wherein the hydromorphone conjugate is 3-cinnamate-hydromorphone , a pharmaceutically acceptable salt thereof , or a combination thereof.3. The composition of claim 1 , wherein the hydromorphone conjugate and/or at least one pharmaceutically acceptable salt thereof is used to treat narcotic or opioid abuse; to prevent narcotic or opioid withdrawal; to treat moderate to severe pain; to reduce or prevent oral claim 1 , intranasal or intravenous drug abuse; or to provide oral claim 1 , intranasal claim 1 , or parenteral drug abuse resistance.4. The composition of claim 1 , wherein the hydromorphone conjugate and/or at least one pharmaceutically acceptable salt thereof is provided in a dosage form selected from the group consisting of a tablet claim 1 , a capsule claim 1 , a caplet claim 1 , a suppository claim 1 , a troche claim 1 , a lozenge claim 1 , a powder claim 1 , a solution claim 1 , a film claim 1 , a thin strip claim 1 , a slurry claim 1 , a suspension claim 1 , a gel claim 1 , a strip claim 1 , a rectal film claim 1 , a transdermal patch claim 1 , a syrup claim 1 , and an inhalation compound.5. The composition of claim 1 , wherein the composition is formulated for oral administration.6. The composition of claim 5 , wherein oral administration of the hydromorphone conjugate and/or at least one pharmaceutically acceptable salt thereof results in an improved rate of release ...

Bioreactor system

A method for regulating parameters of at least two bioreactor bags individually, which bioreactor bags are provided on one and the same rocking part of a bioreactor system. The method includes the steps of: determining an individual weight of the content in each bioreactor bag at different points in time during processing; regulating one or more parameters in each bioreactor bag in dependence of the individual weights.

SYSTEM AND METHOD FOR CREATING CUSTOM COMPOSITE IMAGES FROM LAYERED IMAGES IN A CLIENT-SERVER ENVIRONMENT

In response to receiving a request from a client device, a first image can be determined based at least in part on an image identification in the request. The first image may be associated with a plurality of layers. A subset of the plurality of layers can be determined. Information configured to enable a selection of at least one layer in the subset may be sent to the client device. In response to receiving a request from a client device, a composite image can be obtained based at least in part on a selection of at least one layer of a plurality of layers of an image received in the request. The composite image may be dynamically generated or retrieved from a storage device. The composite image and/or information associated with the composite image can be sent to the client device. 1. A method for generating a composite image from a multilayer image in a client-server environment , the method comprising:receiving, by a server via a network, a request comprising image search criteria and a layer selection;identifying, by the server, a multilayer image from a plurality of possible multilayer images based on the image search criteria;selecting, by the server, layers of the multilayer image based on the layer selection;generating, by the server, a flattened composite image comprising image data from only the selected layers of the multilayer image; andsending, by the server, the flattened composite image to a client device that initiated the request.2. The method of claim 1 , wherein the image search criteria comprises a plurality of different selection criteria claim 1 , said identifying the multilayer image comprises satisfying the plurality of different selection criteria.3. The method of claim 1 , wherein the multilayer image is one of a plurality of multilayer images identified by the image search criteria claim 1 , the server generating a plurality of a flattened composite images that correspond to the plurality of identified multilayer images and the layer ...

METHOD FOR SYNTHESISING AN UNSATURATED MACROCYCLIC KETONE

A method for producing unsaturated macrocyclic monoketones comprising the following steps: (a) preparing macrocyclic dienes with a ring size of at least 9 carbon atoms; (b) contacting the starting materials from step (a) with (b1) a palladium(II) salt and/or a palladium(II) complex; and (b2) an oxidant; and (b3) a solvent; and optionally (b4) a ligand; and optionally (b5) a co-catalyst; and optionally (b6) an acid. 1. A method for preparing unsaturated macrocyclic monoketones comprising the following steps(a) providing macrocyclic dienes having a ring size of at least 9 carbon atoms; (b1) a palladium(II) salt and/or a palladium(II) complex; and', '(b2) an oxidant; and', '(b3) a solvent; and optionally', '(b4) a ligand; and optionally', '(b5) a cocatalyst; and optionally', '(b6) an acid., '(b) contacting the starting materials from step (a) with'}2. The method as claimed in claim 1 , wherein the solvent (b3) is a polar aprotic solvent and selected from the group consisting of N claim 1 ,N-disubstituted open-chain and cyclic acid amides claim 1 , for example dimethylformamide claim 1 , dimethylacetamide claim 1 , diethylacetamide claim 1 , dimethylpropionamide claim 1 , N-methylpyrrolidone claim 1 , aliphatic claim 1 , cycloaliphatic or aromatic nitriles such as acetonitrile claim 1 , propionitrile or benzonitrile claim 1 , or linear and cyclic ethers claim 1 , cyclic carbonates claim 1 , and lactones claim 1 , and mixtures thereof.3. The method as claimed in claim 1 , wherein the ligand (b4) is mandatory claim 1 , is a bidentate ligand and contains N claim 1 ,N claim 1 , N claim 1 ,O claim 1 , N claim 1 ,S claim 1 , or O claim 1 ,O donor atoms.4. The method as claimed in claim 1 , wherein the palladium(II) salt and/or the palladium(II) complex (b1) are selected from the group consisting of palladium chloride claim 1 , palladium bromide claim 1 , H2PdCl4 claim 1 , Li2PdCl4 claim 1 , Na2PdCl4 claim 1 , K2PdCl4 claim 1 , (NH4)2PdCl4 claim 1 , palladium acetate claim 1 , ...

LIQUID PHARMACEUTICAL COMPOSITIONS COMPRISING PERGOLIDE

The invention relates to novel liquid pharmaceutical compositions comprising (8β)-8-[(methylthio)methyl]-6-propylergoline (pergolide) as well as corresponding processes of manufacturing such liquid pharmaceutical compositions and their medical uses. 2. The liquid pharmaceutical composition according to claim 1 , wherein pergolide is micronized pergolide mesylate.3. The liquid pharmaceutical composition according to claim 1 , wherein the liquid pharmaceutical composition is a suspension.4. The liquid pharmaceutical composition according to claim 3 , wherein the suspension is an oily suspension claim 3 , i.e. a suspension comprising one or more oil(s) claim 3 , such as mineral oil(s) and/or vegetable oil(s).5. The liquid pharmaceutical composition according to claim 4 , wherein the oily suspension is devoid of any water.6. The liquid pharmaceutical composition according to claim 4 , wherein the one or more oil(s) are selected form the group consisting of: refined soyabean oil claim 4 , refined safflower oil claim 4 , refined maize oil claim 4 , virgin linseed oil claim 4 , refined sunflower oil claim 4 , refined rapeseed oil claim 4 , and miglyol [mixture of medium-chain triglycerides (MCT) claim 4 , in particular of saturated fatty acids claim 4 , such as caprylic acid and capric/caprinic acid] claim 4 , wherein preferably the miglyol is selected from the group consisting of: Miglyol 810 claim 4 , Miglyol claim 4 , 812 claim 4 , Miglyol 829 claim 4 , Miglyol 840 claim 4 , more preferably Miglyol 812.7. The liquid pharmaceutical composition according to claim 1 , wherein the liquid pharmaceutical composition further comprises at least one antioxidant claim 1 , preferably selected from the group consisting of: butylhydroxytoluene (BHT) claim 1 , ascorbyl palmitate (AP) claim 1 , butylhydroxyanisole (BHA) claim 1 , and alpha-tocopheryl acetate (AT) claim 1 , more preferably butylhydroxyanisole (BHA).8. The liquid pharmaceutical composition according to claim 4 , wherein ...

UPDATING SUB-SYSTEMS OF A DEVICE USING BLOCKCHAIN

In general, techniques are described by which provide a technique for securely updating sub-systems of a device. A device includes multiple sub-systems including a first sub-system and a second sub-system. Each sub-system includes one or more processors. One or more processors of the first sub-system may be configured to perform the techniques herein. The one or more processors of the first sub-system are configured to download, from one or more nodes of a network, a sub-system update for the second sub-system in response to detecting an update to a ledger of a blockchain associated with the second sub-system. The one or more processors of the first sub-system are further configured to distribute the sub-system update for the second sub-system to the second sub-system. 1. A device comprising:a plurality of sub-systems including a first sub-system and a second sub-system, 'monitor a ledger of a first blockchain for an update associated with the second sub-system;', 'wherein each sub-system of the plurality of sub-systems comprise one or more processors, and wherein the one or more processors of the first sub-system are configured to 'distribute the sub-system update for the second sub-system to the second sub-system, and', 'download, from one or more nodes of a network, an update file for a sub-system update for the second sub-system in response to detecting the update to associated with the second sub-system, wherein the first sub-system is different than the second sub-system, wherein the first blockchain comprises information indicating sub-system updates for respective ones of the plurality of sub-systems, wherein a second blockchain comprises the update file for the sub-system update and an update file for each previous sub-system update for the second sub-system; and'}wherein the one or more processors of the second sub-system is configured to install the update file using a sub-system update decryption key for the second sub-system, wherein only the second sub ...

SECURE INSTALLATION OF APPROVED PARTS USING BLOCKCHAIN

In general, techniques are described by which provide verification of parts installed to a device. A device comprising one or more sensors one or more processors implemented in circuitry may be configured to perform the techniques herein. The one or more processors are in communication with the one or more sensors and are configured to determine, in response to detecting an installation of a component for the device, an operating characteristic of the component measured by the one or more sensors. The one or more processors are further configured to verify, based at least in part on a comparison of the operating characteristic of the component and an approved operating characteristic for the component stored in a blockchain, that the component is an approved component for the device. 1. A device comprising:one or more sensors; and determine, in response to detecting an installation of a component for the device, an operating characteristic of the component measured by the one or more sensors; and', 'verify, based at least in part on a comparison of the operating characteristic of the component and an approved operating characteristic for the component stored in a blockchain, that the component is an approved component for the device., 'one or more processors implemented in circuitry, the one or more processors in communication with the one or more sensors and configured to2. The device of claim 1 , wherein the operating characteristic measured by the one or more sensors comprises one or more of accelerometer data for the component claim 1 , accelerometer data for the device claim 1 , an operating temperature for the component claim 1 , an operating temperature for the device claim 1 , a measurement of distance traveled by the device claim 1 , a sound of the component during operation claim 1 , a performance metric of the component claim 1 , a rotational frequency of the component claim 1 , a vibration frequency of the component claim 1 , exhaust values of the device ...

FINISHING SYSTEM AND METHOD OF OPERATING

A finishing system includes a workpiece carrier configured to hold a workpiece, and a plurality of work stations arranged in a row along an axis defining a process line, each of the plurality of work stations configured to receive the workpiece and treat the workpiece. A hoist runway, including fixed and movable rail sections, extends along the plurality of work stations of the process line. A hoist is movable along the hoist runway to traverse the plurality of work stations, the hoist coupled to the workpiece carrier to raise and lower the workpiece carrier and to move the workpiece carrier along the process line. A side transfer mechanism moves the movable rail section, with the hoist situated thereon, in a direction transverse to the axis so that the hoist is movable out of the process line. 1. A finishing system comprising:a workpiece carrier configured to hold a workpiece;a plurality of work stations arranged in a row along an axis defining a process line, each of the plurality of work stations configured to receive the workpiece and treat the workpiece;a hoist runway extending along the plurality of work stations of the process line, the hoist runway including fixed and movable rail sections;a hoist movable along the hoist runway to traverse the plurality of work stations, wherein the hoist is coupled to the workpiece carrier to raise and lower the workpiece carrier and to move the workpiece carrier along the process line; anda side transfer mechanism configured to move the movable rail section, with the hoist situated thereon, in a direction transverse to the axis so that the hoist is movable out of the process line.2. The finishing system of claim 1 , wherein the side transfer mechanism comprises a cart having a motor operable to drive the cart along a transverse shuttle track.3. The finishing system of claim 2 , wherein the movable rail section is fixedly secured to the cart.4. The finishing system of claim 1 , further comprising a secondary hoist runway ...

Method and device for measuring the flow of a fluid

Catalyst composition for polymerization of cycloolefins

The invention relates to a catalyst composition for polymerization of norbornene-type monomer: including WCl 4 O and WCl 6 in a molar ratio of WCl 4 O to WCl 6 from 1:9 to 1:1 (i.e., 10-50% WOCl 4 and 90-50% WCl 6 ). The method of making catalyst includes: providing catalyst precursor material, the major portion of which is WCl 6 , and contacting controlled proportions of the oxygen donor and WCl 6 to form WCl 4 O in a molar ratio to WCl 6 of between 1:9 and 1:1.

Catalyst containing wc16

SENSOR FOR DETERMINING AN ENZYME SUBSTRATE