06-02-2014 дата публикации
Номер: US20140039640A1
Methods of providing dose controlled application of bone graft materials are disclosed. In particular, methods for determining a target quantity of bone graft material for clinical application in order to ensure maximum clinical results are provided. These methods comprise determining the target weight of the material to be applied. 1. A method of preparing a graft implant , comprising:providing a compressible or expandable, porous, graft material;determining a target porosity value for the graft implant;calculating a target weight for the amount of graft material to be used; andforming an implant with a quantity of material representing the determined target weight calculated.2. The method of claim 1 , wherein the step of determining the target porosity value comprises determining a physical parameter of a defect.3. The method of claim 2 , wherein the physical parameter comprises a dimension claim 2 , size claim 2 , geometry claim 2 , volume claim 2 , surface area claim 2 , anatomic location claim 2 , or extent of damage.4. The method of claim 1 , wherein the step of determining a target weight comprises determining the porosity of the graft material.5. The method of claim 4 , wherein the step of determining a target weight comprises determining a percentage value of volume occupied by the material.6. The method of claim 1 , wherein the bone graft material comprises bioactive glass fibers claim 1 , particles claim 1 , granules claim 1 , clusters claim 1 , or combinations thereof.7. The method of claim 1 , wherein the implant is a bone graft implant claim 1 , and the material comprises bone graft material.8. A method of treating a defect claim 1 , comprising:determining a target porosity value for a graft implant for treating the defect;providing a compressible or expandable, porous, graft material;calculating a target weight for the amount of graft material to be used;forming an implant with a quantity of material representing the determined target weight ...
Подробнее