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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 36. Отображено 36.
06-09-2016 дата публикации

Posterior vertebral plating system

Номер: US0009433443B2

A posterior vertebral plating system comprising a plate and a plurality of attachment members. The plate has a plurality of holes extending through the plate from an upper surface to a lower surface, and the plate is configured to extend along the posterior side of at least two vertebrae adjacent at least one boney structure of each of the vertebrae. The holes are spaced in such a way that a first plurality of holes is positionable over a boney structure of a first vertebra to define a plurality of fixation points to the first vertebra and a second plurality of holes is positionable over boney structure of a second vertebra to define a plurality of fixation points to the second vertebra. The attachment members are insertable through the holes of the plate and into the boney structure of a corresponding vertebra to fix the plate to the vertebra.

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14-11-2017 дата публикации

Method of dose controlled application of bone graft materials by weight

Номер: US0009814804B2
Принадлежит: PROSIDYAN, INC., PROSIDYAN INC

Methods of providing dose controlled application of bone graft materials are disclosed. In particular, methods for determining a target quantity of bone graft material for clinical application in order to ensure maximum clinical results are provided. These methods comprise determining the target weight of the material to be applied.

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08-09-2016 дата публикации

METHOD OF DOSE CONTROLLED APPLICATION OF BONE GRAFT MATERIALS BY WEIGHT

Номер: US20160256609A1
Принадлежит:

Methods of providing dose controlled application of bone graft materials are disclosed. In particular, methods for determining a target quantity of bone graft material for clinical application in order to ensure maximum clinical results are provided. These methods comprise determining the target weight of the material to be applied. 1. A method of providing consistent , dose controlled application of a graft material to a defect , comprising:providing a compressible or expandable, porous graft material;determining a density value of the graft material;calculating a target weight of a quantity of the graft material to be applied based on the determined density value; andapplying the quantity of graft material representing the target weight calculated to the defect.2. The method of claim 1 , further comprising the step of forming a graft implant from the quantity of graft material representing the target weight calculated prior to the applying step.3. The method of claim 1 , wherein the step of calculating a target weight comprises determining the porosity of the graft material.4. The method of claim 3 , wherein the step of calculating a target weight comprises determining a percentage value of volume occupied by the graft material.5. The method of claim 4 , further including the step of molding the graft material into a shape corresponding to the determined percentage value of volume.6. The method of claim 1 , wherein the graft material is in the form of fibers claim 1 , particles claim 1 , granules claim 1 , clusters claim 1 , or combinations thereof.7. The method of claim 1 , wherein the graft material comprises silicone claim 1 , calcium claim 1 , sodium claim 1 , or phosphate.8. The method of claim 1 , wherein the defect is a bone defect claim 1 , and the graft material comprises bone graft material.9. A method of providing consistent claim 1 , dose controlled application of a compressible or expandable claim 1 , porous graft material to a defect claim 1 , ...

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08-12-2016 дата публикации

POSTERIOR VERTEBRAL PLATING SYSTEM

Номер: US20160354122A1
Принадлежит:

A posterior vertebral plating system comprising a plate and a plurality of attachment members. The plate has a plurality of holes extending through the plate from an upper surface to a lower surface, and the plate is configured to extend along the posterior side of at least two vertebrae adjacent at least one boney structure of each of the vertebrae. The holes are spaced in such a way that a first plurality of holes is positionable over a boney structure of a first vertebra to define a plurality of fixation points to the first vertebra and a second plurality of holes is positionable over boney structure of a second vertebra to define a plurality of fixation points to the second vertebra. The attachment members are insertable through the holes of the plate and into the boney structure of a corresponding vertebra to fix the plate to the vertebra. 1. A posterior vertebral plating system , comprising:a plate having an upper surface, a lower surface, and a plurality of holes extending through the plate from the upper surface to the lower surface, the plate being configured to extend along the posterior side of at least two vertebrae adjacent at least one lateral mass of each of the vertebra and the holes being spaced in such a way that a first plurality of holes is positionable over the lateral mass of a first vertebra to define a plurality of fixation points to the first vertebra and a second plurality of holes is positionable over the lateral mass of a second vertebra to define a plurality of fixation points to the second vertebra, anda plurality of attachment members insertable through the holes of the plate and into the lateral mass of a corresponding vertebra to fix the plate to the vertebra,in which the holes are arranged in at least two longitudinal rows of holes with the holes of one longitudinal row of holes being staggered relative to the holes of the other longitudinal row of holes, the first plurality of holes being arranged in a triangular group of three ...

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27-10-2016 дата публикации

BONE GRAFT IMPLANTS CONTAINING ALLOGRAFT

Номер: US20160310638A1
Принадлежит:

Synthetic, bioactive ultra-porous bone graft materials having an engineered porosity, and implants formed from such materials are provided. In particular, these implants comprise bioactive glass and incorporate allograft material for osteoinduction. The implants are suitable for bone tissue regeneration and/or repair. 1. A porous , composite bone graft implant comprising:a bioactive glass material in the form of fibers;a bioactive material in the form of granules; andan allograft material;wherein the composite implant comprises a pore size distribution including at least a nanoporosity.2. The implant of claim 1 , wherein the pore size distribution includes pores characterized by pore diameters ranging from about 100 nanometers to about 1 millimeter.3. The implant of claim 1 , further configured for staged resorption.4. The implant of claim 1 , wherein the bioactive glass material is selected from the group consisting of sol gel derived bioactive glass claim 1 , melt derived bioactive glass claim 1 , silica based bioactive glass claim 1 , silica free bioactive glass claim 1 , phosphate based bioactive glass claim 1 , crystallized bioactive glass claim 1 , and bioactive glass containing trace elements.5. The implant of claim 1 , wherein the bioactive glass material comprises a silica free bioactive glass selected from the group consisting of borate based bioactive glass and phosphate based bioactive glass.6. The implant of claim 1 , wherein the bioactive glass material comprises a partially crystallized or fully crystallized bioactive glass.7. The implant of claim 1 , further comprising a carrier material.8. The implant of claim 7 , wherein the carrier material comprises collagen.9. The implant of claim 7 , wherein the carrier material comprises phospholipids claim 7 , carboxylmethylcellulose (CMC) claim 7 , glycerin claim 7 , polyethylene glycol (PEG) claim 7 , polylactic acid (PLA) claim 7 , polylactic-co-glycolic acid (PLGA) claim 7 , or other copolymers of the ...

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11-04-2013 дата публикации

POSTERIOR VERTEBRAL PLATING SYSTEM

Номер: US20130090688A1
Принадлежит:

A posterior vertebral plating system comprising a plate and a plurality of attachment members. The plate has a plurality of holes extending through the plate from an upper surface to a lower surface, and the plate is configured to extend along the posterior side of at least two vertebrae adjacent at least one boney structure of each of the vertebrae. The holes are spaced in such a way that a first plurality of holes is positionable over a boney structure of a first vertebra to define a plurality of fixation points to the first vertebra and a second plurality of holes is positionable over boney structure of a second vertebra to define a plurality of fixation points to the second vertebra. The attachment members are insertable through the holes of the plate and into the boney structure of a corresponding vertebra to fix the plate to the vertebra. 1. A posterior vertebral plating system , comprising:a plate having an upper surface, a lower surface, and a plurality of holes extending through the plate from the upper surface to the lower surface, the plate being configured to extend along the posterior side of at least two vertebrae adjacent at least one lateral mass of each of the vertebra and the holes being spaced in such a way that a first plurality of holes is positionable over the lateral mass of a first vertebra to define a plurality of fixation points to the first vertebra and a second plurality of holes is positionable over the lateral mass of a second vertebra to define a plurality of fixation points to the second vertebra; anda plurality of attachment members insertable through the holes of the plate and into the lateral mass of a corresponding vertebra to fix the plate to the vertebra.2. The posterior vertebral plating system of claim 1 , wherein the holes are arranged in at least two longitudinal rows of holes with the holes of one longitudinal row of holes being staggered relative to the holes of the other longitudinal row of holes.3. The posterior ...

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06-02-2014 дата публикации

METHOD OF DOSE CONTROLLED APPLICATION OF BONE GRAFT MATERIALS BY WEIGHT

Номер: US20140039640A1
Принадлежит: PROSIDYAN, INC.

Methods of providing dose controlled application of bone graft materials are disclosed. In particular, methods for determining a target quantity of bone graft material for clinical application in order to ensure maximum clinical results are provided. These methods comprise determining the target weight of the material to be applied. 1. A method of preparing a graft implant , comprising:providing a compressible or expandable, porous, graft material;determining a target porosity value for the graft implant;calculating a target weight for the amount of graft material to be used; andforming an implant with a quantity of material representing the determined target weight calculated.2. The method of claim 1 , wherein the step of determining the target porosity value comprises determining a physical parameter of a defect.3. The method of claim 2 , wherein the physical parameter comprises a dimension claim 2 , size claim 2 , geometry claim 2 , volume claim 2 , surface area claim 2 , anatomic location claim 2 , or extent of damage.4. The method of claim 1 , wherein the step of determining a target weight comprises determining the porosity of the graft material.5. The method of claim 4 , wherein the step of determining a target weight comprises determining a percentage value of volume occupied by the material.6. The method of claim 1 , wherein the bone graft material comprises bioactive glass fibers claim 1 , particles claim 1 , granules claim 1 , clusters claim 1 , or combinations thereof.7. The method of claim 1 , wherein the implant is a bone graft implant claim 1 , and the material comprises bone graft material.8. A method of treating a defect claim 1 , comprising:determining a target porosity value for a graft implant for treating the defect;providing a compressible or expandable, porous, graft material;calculating a target weight for the amount of graft material to be used;forming an implant with a quantity of material representing the determined target weight ...

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02-01-2020 дата публикации

BIOACTIVE POROUS BONE GRAFT IMPLANTS

Номер: US20200000970A1
Принадлежит:

Bioactive porous bone graft implants in various forms suitable for bone tissue regeneration and/or repair, as well as methods of use, are provided. The implants are formed of bioactive glass and have an engineered porosity. The implants may take the form of a putty, foam, fibrous cluster, fibrous matrix, granular matrix, or combinations thereof and allow for enhanced clinical results as well as ease of handling. 1. A bone graft implant , comprising:a first component comprising a bioactive glass material in the form of a plurality of glass fibers; anda second component comprising a bioactive glass material in the form of a bioactive glass crust at least partially covering the plurality of fibers;each of the first and second components having a different resorption capacity than the other component; anda third component comprising a biological agent;wherein the implant comprises a pore size distribution including pores characterized by pore diameters ranging from about 100 nanometers to about 1 millimeter.2. The implant of claim 1 , wherein at least one of the first and second components is partially or fully sintered.3. The implant of claim 1 , wherein at least one of the first and second components is porous.4. The implant of claim 1 , wherein the first component further comprises bioactive glass granules.5. The implant of claim 4 , wherein the bioactive glass crust extends over all of the plurality of fibers and granules.6. The implant of claim 1 , wherein the biological agent is selected from the group consisting of stem cells claim 1 , demineralized bone matrix claim 1 , bone marrow and platelet rich plasma.7. The implant of claim 1 , wherein the biological agent is selected from the group consisting of bone morphogenic protein claim 1 , a bone growth factor claim 1 , vascular endothelial growth factor claim 1 , insulin derived growth factor claim 1 , a keratinocyte derived growth factor claim 1 , and a fibroblast derived growth factor.8. The implant of claim 1 , ...

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08-01-2015 дата публикации

POSTERIOR VERTEBRAL PLATING SYSTEM

Номер: US20150012039A1
Принадлежит:

A posterior vertebral plating system comprising a plate and a plurality of attachment members. The plate has a plurality of holes extending through the plate from an upper surface to a lower surface, and the plate is configured to extend along the posterior side of at least two vertebrae adjacent at least one boney structure of each of the vertebrae. The holes are spaced in such a way that a first plurality of holes is positionable over a boney structure of a first vertebra to define a plurality of fixation points to the first vertebra and a second plurality of holes is positionable over boney structure of a second vertebra to define a plurality of fixation points to the second vertebra. The attachment members are insertable through the holes of the plate and into the boney structure of a corresponding vertebra to fix the plate to the vertebra. 1. A posterior vertebral plating system , comprising:a plate having an upper surface, a lower surface, and a plurality of holes extending through the plate from the upper surface to the lower surface, the plate being configured to extend along a posterior ring of a C1 vertebra to a posterior side of a C2 vertebra, the holes being spaced in such a way that a first plurality of holes is positionable over the posterior ring of the C1 vertebra to define a plurality of fixation points to the C1 vertebra and a second plurality of holes is positionable over the posterior side of the C2 vertebra to define a plurality of fixation points to the C2 vertebra; anda plurality of attachment members insertable through the holes of the plate and into the posterior ring of the C1 vertebra to the posterior side of the C2 vertebra to fix the plate to the vertebra.2. The posterior vertebral plating system of claim 1 , wherein the plate comprises:a spacer portion having a first end and a second end and a longitudinal length generally corresponding to the distance between the posterior ring of the C1 vertebra and the lamina of the C2 vertebra;a ...

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05-03-2015 дата публикации

BIOACTIVE POROUS BONE GRAFT IMPLANTS

Номер: US20150064229A1
Принадлежит:

Bioactive porous bone graft implants in various forms suitable for bone tissue regeneration and/or repair, as well as methods of use, are provided. The implants are formed of bioactive glass and have an engineered porosity. The implants may take the form of a putty, foam, fibrous cluster, fibrous matrix, granular matrix, or combinations thereof and allow for enhanced clinical results as well as ease of handling. 1. A porous , composite foam implant for bone grafting , comprising:a first component comprising a bioactive glass material; anda second component comprising a bioactive material;each of the components having a different resorption capacity than the other component;wherein the foam implant comprises a pore size distribution including pores characterized by pore diameters ranging from about 100 nanometers to about 1 millimeter.2. The implant of claim 1 , wherein the bioactive glass material comprises bioactive glass fibers or bioactive glass granules.3. The implant of claim 1 , wherein the second material comprises a bioactive glass or glass-ceramic.4. The implant of claim 1 , wherein at least one of the first and second components is partially or fully sintered.5. The implant of claim 1 , wherein at least one of the first and second components is porous.6. The implant of claim 1 , wherein the second component is a porous coating.7. The implant of claim 1 , wherein the first component comprises bioactive glass fibers claim 1 , and the second component comprises a coating over each of the fibers.8. The implant of claim 1 , wherein the first component comprises bioactive glass fibers claim 1 , and the second component comprises a coating over the plurality of fibers.9. The implant of claim 1 , wherein the first component comprises bioactive glass granules claim 1 , and the second component comprises a coating over each of the granules.10. The implant of claim 1 , wherein the first component comprises bioactive glass granules claim 1 , and the second component ...

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17-03-2022 дата публикации

BIOACTIVE POROUS BONE GRAFT IMPLANTS

Номер: US20220080085A1
Принадлежит:

Bioactive porous bone graft implants in various forms suitable for bone tissue regeneration and/or repair, as well as methods of use, are provided. The implants are formed of bioactive glass and have an engineered porosity. The implants may take the form of a putty, foam, fibrous cluster, fibrous matrix, granular matrix, or combinations thereof and allow for enhanced clinical results as well as ease of handling. 1. A bone graft implant , comprising:a first component comprising a bioactive glass material in the form of a plurality of glass fibers; anda second component comprising a bioactive glass material in the form of a bioactive glass crust at least partially covering the plurality of fibers;each of the first and second components having a different resorption capacity than the other component; anda third component comprising a biological agent;wherein the implant comprises a pore size distribution including pores characterized by pore diameters ranging from about 100 nanometers to about 1 millimeter.2. The implant of claim 1 , wherein at least one of the first and second components is partially or fully sintered.3. The implant of claim 1 , wherein at least one of the first and second components is porous.4. The implant of claim 1 , wherein the first component further comprises bioactive glass granules.5. The implant of claim 4 , wherein the bioactive glass crust extends over all of the plurality of fibers and granules.6. The implant of claim 1 , wherein the biological agent is selected from the group consisting of stem cells claim 1 , demineralized bone matrix claim 1 , bone marrow and platelet rich plasma.7. The implant of claim 1 , wherein the biological agent is selected from the group consisting of bone morphogenic protein claim 1 , a bone growth factor claim 1 , vascular endothelial growth factor claim 1 , insulin derived growth factor claim 1 , a keratinocyte derived growth factor claim 1 , and a fibroblast derived growth factor.8. The implant of claim 1 , ...

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12-03-2015 дата публикации

BIOACTIVE POROUS BONE GRAFT COMPOSITIONS WITH COLLAGEN

Номер: US20150071983A1
Принадлежит:

Bioactive porous bone graft implants in various forms suitable for use in bone tissue regeneration and/or repair, as well as methods of use are provided. The implants are formed of bioactive glass and have an engineered porosity. The implants may be contained in polymer for enhanced clinical results and better handling. 1. A porous , composite bone graft implant , comprising:a first component comprising a bioactive glass material in the form of a plurality of glass fibers, the plurality of glass fibers being randomly arranged throughout the implant; anda second component comprising a collagen material for incorporation with the plurality of glass fibers;each of the components having a different resorption capacity than the other component;wherein the composite implant comprises a pore size distribution including pores characterized by pore diameters ranging from about 100 nanometer to about 1 millimeter.2. The implant of claim 1 , wherein the bioactive glass material is selected from the group consisting of sol gel derived bioactive glass claim 1 , melt derived bioactive glass claim 1 , silica based bioactive glass claim 1 , silica free bioactive glass claim 1 , phosphate based bioactive glass claim 1 , crystallized bioactive glass claim 1 , and bioactive glass containing trace elements.3. The implant of claim 2 , wherein the bioactive glass material comprises a silica free bioactive glass selected from the group consisting of borate based bioactive glass and phosphate based bioactive glass.4. The implant of claim 2 , wherein the bioactive glass material comprises a partially crystallized or fully crystallized bioactive glass.5. The implant of claim 1 , wherein the plurality of glass fibers are in the form of granules or clusters.6. The implant of claim 1 , further including a silane coating on at least some or all of the glass fibers.7. The implant of claim 1 , further including a bioactive glass coating on the plurality of glass fibers.8. The implant of claim 7 , ...

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26-03-2020 дата публикации

DYNAMIC BIOACTIVE BONE GRAFT MATERIAL HAVING AN ENGINEERED POROSITY

Номер: US20200093963A1
Принадлежит:

The present disclosure relates to a dynamic bioactive bone graft material having an engineered porosity. In one embodiment, a bone graft material is provided having bioactive glass fibers arranged in a porous matrix that is moldable into a desired shape for implantation. The material can be substantially without additives and can include at least one nanofiber. The porous matrix may include a combination of one or more pore sizes including nanopores, macropores, mesopores, and micropores. In another embodiment, a bone graft implant is provided having a matrix comprising a plurality of overlapping and interlocking bioactive glass fibers, and having a distributed porosity based on a range of pores provided in the bioactive glass fibers. The distributed porosity can comprise a combination of macropores, mesopores, and micropores, and the matrix can be formable into a desired shape for implantation into a patient. 1. A method of treating a bone defect , comprising:providing a bone graft material, the material comprising:a porous matrix comprising a plurality of overlapping and interlocking bioactive glass fibers and bioactive glass particulates distributed throughout the fibers, the fibers and particulates each having varying diameters, and a range of pores defined by the spaces between said fibers and particulates, the varying diameters of the fibers and particulates controlling pore size and distribution of the range of pores and overall porosity of the matrix, the matrix further having a distributed porosity based on said range of pores such that the matrix is configured for staged resorption, the range of pores comprising micropores and macropores;forming an implant from the bone graft material, the implant being formed by shaping the material into a shape and size for insertion into the bone defect; andimplanting the formed implant into the bone defect.2. The method of claim 1 , wherein the range of pores further comprises nanopores or mesopores.3. The method of ...

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04-04-2019 дата публикации

IMPLANTABLE FUSION DEVICES COMPRISING BIOACTIVE GLASS

Номер: US20190099515A1
Принадлежит:

Implantable devices that comprise an improved bone graft material, such as for example, bioactive glass, are disclosed. Additionally, implantable devices that work in conjunction with an improved bone graft material and act as a composite implantable device, for the improved treatment of bone, are also disclosed. These devices are bioactive, and are engineered to provide enhanced cellular activity to promote bone fusion or regrowth. 1. An implantable device comprising:a main body comprising a plurality of compressed bioactive glass fibers and at least one bundle of compressed bioactive glass fibers within the main body, the main body and the at least one bundle having different fiber densities and porosities;wherein the device has a shape and geometry configured for insertion between adjacent bone segments to facilitate bone fusion.2. The implantable device of claim 1 , further comprising a plurality of bioactive glass particulates in the main body or the bundle.3. The implantable device of claim 1 , wherein the bioactive glass fibers of the main body or at least one bundle are randomly oriented.4. The implantable device of claim 1 , wherein the bioactive glass fibers of the main body or at least one bundle are aligned with respect to one another.5. The implantable device of claim 1 , wherein the bioactive glass fibers of the main body or at least one bundle are sintered together.6. The implantable device of claim 1 , wherein the device comprises a plurality of bundles of compressed bioactive glass fibers within the main body.7. The implantable device of claim 6 , wherein the plurality of bundles of compressed bioactive glass fibers are equidistantly spaced apart from one another within the main body.8. The implantable device of claim 1 , wherein the adjacent bone segments are vertebral bodies.9. The implantable device of claim 1 , wherein the device is porous.10. The implantable device of claim 1 , wherein the device is bioresorbable.11. The implantable device of ...

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18-09-2014 дата публикации

Bone graft implants containing allograft

Номер: US20140271779A1
Принадлежит: Prosidyan Inc

Synthetic, bioactive ultra-porous bone graft materials having an engineered porosity, and implants formed from such materials are provided. In particular, these implants comprise bioactive glass and incorporate allograft material for osteoinduction. The implants are suitable for bone tissue regeneration and/or repair.

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18-09-2014 дата публикации

BIOACTIVE POROUS BONE GRAFT IMPLANTS

Номер: US20140271785A1
Принадлежит: PROSIDYAN, INC.

Bioactive porous bone graft implants in various forms suitable for bone tissue regeneration and/or repair, as well as methods of use, are provided. The implants are formed of bioactive glass and have an engineered porosity. The implants may take the form of a putty, foam, fibrous cluster, fibrous matrix, granular matrix, or combinations thereof and allow for enhanced clinical results as well as ease of handling. 1. A porous , composite bone graft implant comprising:a first component comprising a bioactive glass material; anda second component comprising a bioactive material;each of the components having a different resorption capacity than the other component;wherein the composite implant comprises a pore size distribution including pores characterized by pore diameters ranging from about 100 nanometers to about 1 millimeter.2. The implant of claim 1 , wherein the bioactive glass material comprises bioactive glass fibers or bioactive glass granules.3. The implant of claim 1 , wherein the second material comprises a bioactive glass or glass-ceramic.4. The implant of claim 1 , wherein at least one of the first and second components is partially or fully sintered.5. The implant of claim 1 , wherein at least one of the first and second components is porous.6. The implant of claim 1 , wherein the second component is a porous coating.7. The implant of claim 1 , wherein the first component comprises bioactive glass fibers claim 1 , and the second component comprises a coating over each of the fibers.8. The implant of claim 1 , wherein the first component comprises bioactive glass fibers claim 1 , and the second component comprises a coating over the plurality of fibers.9. The implant of claim 1 , wherein the first component comprises bioactive glass granules claim 1 , and the second component comprises a coating over each of the granules.10. The implant of claim 1 , wherein the first component comprises bioactive glass granules claim 1 , and the second component comprises ...

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18-09-2014 дата публикации

Bioactive porous bone graft compositions in synthetic containment

Номер: US20140271786A1
Принадлежит: Prosidyan Inc

Bioactive porous bone graft implants in various forms suitable for use in bone tissue regeneration and/or repair, as well as methods of use are provided. The implants are formed of bioactive glass and have an engineered porosity. The implants may be contained in polymer for enhanced clinical results and better handling.

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26-08-2021 дата публикации

BIOACTIVE IMPLANTABLE DEVICES, AND COMPOSITE BIOMATERIALS AND METHODS FOR MAKING THE SAME

Номер: US20210260242A1
Принадлежит:

Implantable medical devices, composite bioactive polymeric biomaterials for forming such devices, and methods for manufacturing these biomaterials and devices are provided. The implantable medical devices are engineered, at least in part, from a composite material comprising a polymer component and a bioactive component incorporated therein to provide bioactivity to the polymeric component for the improved treatment of bone or other purposes. The implantable device may comprise a main body formed of a polymeric framework, and a bioactive glass additive incorporated into the rigid polymeric framework. The implantable device may also comprise a main body and a bioactive component that includes a polyarylretherketone (PAEK) polymer component and a bioactive additive component. The bioactive additive component is incorporated substantially throughout the polymer component to further enhance cellular activity to promote bone fusion and/or regeneration. 137-. (canceled)38. An implantable device , comprising:a main body; anda bioactive component comprising a polyarylretherketone (PAEK) polymer component and a bioactive additive component incorporated substantially throughout the polymer component.39. The implantable device of claim 38 , wherein the bioactive additive component comprises a silica-based bioactive glass claim 38 , a boron-based bioactive material claim 38 , a strontium-based bioactive material or a combination thereof.40. The implantable device of claim 39 , wherein the boron-based bioactive material comprises borate particles.41. The implantable device of claim 39 , wherein the silica-based glass additive comprises 45S5 bioactive materials or Combeite.42. The implantable device of claim 38 , wherein the main body is formed from a framework claim 38 , and the bioactive component is incorporated on claim 38 , or into claim 38 , at least a portion of the framework.43. The implantable device of claim 38 , wherein the main body comprises polyetheretherketone ( ...

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06-12-2018 дата публикации

Posterior Vertebral Plating System

Номер: US20180344362A1
Принадлежит:

A posterior vertebral plating system comprising a plate and a plurality of attachment members. The plate has a plurality of holes extending through the plate from an upper surface to a lower surface, and the plate is configured to extend along the posterior side of at least two vertebrae adjacent at least one boney structure of each of the vertebrae. The holes are spaced in such a way that a first plurality of holes is positionable over a boney structure of a first vertebra to define a plurality of fixation points to the first vertebra and a second plurality of holes is positionable over boney structure of a second vertebra to define a plurality of fixation points to the second vertebra. The attachment members are insertable through the holes of the plate and into the boney structure of a corresponding vertebra to fix the plate to the vertebra. 1. A posterior vertebral plating system , comprising:a plate having an upper surface, a lower surface, and a plurality of holes extending through the plate from the upper surface to the lower surface, the plate being configured to extend along the posterior side of at least two vertebrae adjacent at least one lateral mass of each of the vertebra and the holes being spaced in such a way that a first plurality of holes is positionable over the lateral mass of a first vertebra to define a plurality of fixation points to the first vertebra and a second plurality of holes is positionable over the lateral mass of a second vertebra to define a plurality of fixation points to the second vertebra; anda plurality of attachment members insertable through the holes of the plate and into a corresponding vertebra to fix the plate to the vertebra,wherein the plate comprises a lateral mass plate portion and a lamina plate portion, the plate being configured to be bent along a longitudinal axis between the lateral mass plate portion and the lamina plate portion, the lateral mass plate portion being attachable to lateral masses of ...

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17-03-2017 дата публикации

Dynamic bioactive bone graft material and methods for handling

Номер: ES2606042T3
Принадлежит: Prosidyan Inc

Un kit para preparar un implante de injerto óseo bioactivo dinámico, que comprende: una matriz fibrosa y porosa de fibras de vidrio bioactivo, en la que las fibras se caracterizan por diámetros de fibra que varían entre aproximadamente 5 nanómetros y aproximadamente 100 micrómetros, y en la que la porosidad de la matriz varía entre aproximadamente 100 nanómetros y aproximadamente 1 milímetro; y q una bandeja de molde que incluye un componente de base y un componente de tapa configurado para encajar dentro del componente de base, teniendo cada uno de los componentes de base y de tapa partes rebajadas o elevadas correspondientes para formar una forma moldeada predefinida. A kit for preparing a dynamic bioactive bone graft implant, comprising: a fibrous and porous matrix of bioactive glass fibers, in which the fibers are characterized by fiber diameters ranging between about 5 nanometers and about 100 micrometers, and in the one that the porosity of the matrix varies between approximately 100 nanometers and approximately 1 millimeter; and q a mold tray that includes a base component and a lid component configured to fit within the base component, each of the base and lid components having corresponding lowered or raised portions to form a predefined molded shape.

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18-04-2018 дата публикации

Dynamic bioactive bone graft material having an engineered porosity

Номер: EP2493519B1
Принадлежит: Prosidyan Inc

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18-11-2014 дата публикации

Bioactive porous bone graft compositions in synthetic containment

Номер: US8889178B2
Принадлежит: Prosidyan Inc

Bioactive porous bone graft implants in various forms suitable for use in bone tissue regeneration and/or repair, as well as methods of use are provided. The implants are formed of bioactive glass and have an engineered porosity. The implants may be contained in polymer for enhanced clinical results and better handling.

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11-11-2014 дата публикации

Bioactive porous bone graft implants

Номер: US8883195B2
Принадлежит: Prosidyan Inc

Bioactive porous bone graft implants in various forms suitable for bone tissue regeneration and/or repair, as well as methods of use, are provided. The implants are formed of bioactive glass and have an engineered porosity. The implants may take the form of a putty, foam, fibrous cluster, fibrous matrix, granular matrix, or combinations thereof and allow for enhanced clinical results as well as ease of handling.

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05-07-2016 дата публикации

Bone graft implants containing allograft

Номер: US9381274B2
Принадлежит: Prosidyan Inc

Synthetic, bioactive ultra-porous bone graft materials having an engineered porosity, and implants formed from such materials are provided. In particular, these implants comprise bioactive glass and incorporate allograft material for osteoinduction. The implants are suitable for bone tissue regeneration and/or repair.

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03-11-2011 дата публикации

Bone fixation device and method of validating its proper placement

Номер: WO2011137051A1
Автор: Hyun W. Bae, Timothy Davis
Принадлежит: Bae Hyun W, Timothy Davis

A bone fixation device, in particular a pedicle screw, is provided. The device includes an enhanced bone-to-metal interface, while also having electroconductive properties. Also provided are methods of using the bone fixation device and methods of validating proper placement of the device.

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11-10-2017 дата публикации

Posterior vertebral plating system

Номер: EP3228269A1
Принадлежит: Synthes GmbH

A posterior vertebral plating system comprising a plate and a plurality of attachment members. The plate has a plurality of holes extending through the plate from an upper surface to a lower surface, and the plate is configured to extend along the posterior side of at least two vertebrae adjacent at least one bony structure of each of the vertebrae. The holes are spaced in such a way that a first plurality of holes is positionable over a bony structure of a first vertebra to define a plurality of fixation points to the first vertebra and a second plurality of holes is positionable over bony structure of a second vertebra to define a plurality of fixation points to the second vertebra. The attachment members are insertable through the holes of the plate and into the bony structure of a corresponding vertebra to fix the plate to the vertebra.

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16-10-2012 дата публикации

Intervertebral implant with integrated fixation

Номер: US8287572B2
Принадлежит: Howmedica Osteonics Corp

A system for spinal surgery includes a prosthesis comprising a plurality of bone anchors which engage an intervertebral construct for fusion or motion preservation. The fusion construct comprises a spacer optionally encircled by a jacket. The motion preservation construct may comprise an articulating disc assembly or an elastomeric disc assembly. Any of the constructs may occupy the intervertebral disc space between adjacent vertebrae after removal of an intervertebral disc. The anchors slidingly engage the construct to securely fix the prosthesis to the vertebrae. The anchors and jacket of the fusion construct provide a continuous load path across opposite sides of the prosthesis so as to resist antagonistic motions of the spine.

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04-10-2012 дата публикации

Posterior vertebral plating system

Номер: WO2012135860A2
Принадлежит: Synthes GmbH, Synthes USA, LLC

A posterior vertebral plating system comprising a plate and a plurality of attachment members. The plate has a plurality of holes extending through the plate from an upper surface to a lower surface, and the plate is configured to extend along the posterior side of at least two vertebrae adjacent at least one boney structure of each of the vertebrae. The holes are spaced in such a way that a first plurality of holes is positionable over a boney structure of a first vertebra to define a plurality of fixation points to the first vertebra and a second plurality of holes is positionable over boney structure of a second vertebra to define a plurality of fixation points to the second vertebra. The attachment members are insertable through the holes of the plate and into the boney structure of a corresponding vertebra to fix the plate to the vertebra.

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26-08-2015 дата публикации

Posterior vertebral plating system

Номер: EP2910208A2
Принадлежит: Synthes GmbH

A posterior vertebral plating system comprising a plate and a plurality of attachment members. The plate has a plurality of holes extending through the plate from an upper surface to a lower surface, and the plate is configured to extend along the posterior side of at least two vertebrae adjacent at least one bony structure of each of the vertebrae. The holes are spaced in such a way that a first plurality of holes is positionable over a bony structure of a first vertebra to define a plurality of fixation points to the first vertebra and a second plurality of holes is positionable over bony structure of a second vertebra to define a plurality of fixation points to the second vertebra. The attachment members are insertable through the holes of the plate and into the bony structure of a corresponding vertebra to fix the plate to the vertebra.

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18-07-2018 дата публикации

Bone anchor

Номер: EP3207900B1
Принадлежит: Howmedica Osteonics Corp

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16-03-2023 дата публикации

Dynamic bioactive bone graft material having an engineered porosity

Номер: US20230077763A1
Принадлежит: Prosidyan Inc

The present disclosure relates to a dynamic bioactive bone graft material having an engineered porosity. In one embodiment, a bone graft material is provided having bioactive glass fibers arranged in a porous matrix that is moldable into a desired shape for implantation. The material can be substantially without additives and can include at least one nanofiber. The porous matrix may include a combination of one or more pore sizes including nanopores, macropores, mesopores, and micropores. In another embodiment, a bone graft implant is provided having a matrix comprising a plurality of overlapping and interlocking bioactive glass fibers, and having a distributed porosity based on a range of pores provided in the bioactive glass fibers. The distributed porosity can comprise a combination of macropores, mesopores, and micropores, and the matrix can be formable into a desired shape for implantation into a patient.

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10-09-2024 дата публикации

Bioactive porous bone graft implants

Номер: US12083247B2
Принадлежит: Prosidyan Inc

Bioactive porous bone graft implants in various forms suitable for bone tissue regeneration and/or repair, as well as methods of use, are provided. The implants are formed of bioactive glass and have an engineered porosity. The implants may take the form of a putty, foam, fibrous cluster, fibrous matrix, granular matrix, or combinations thereof and allow for enhanced clinical results as well as ease of handling.

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