PROCESS AND CONFIDENTIAL READING DEVICE OF DATA

SYSTEM AND METHOD FOR CONTROLLING AND MONITORING AN APPARATUS CONTROLLABLE BY AN OPERATOR

CELL INTEGRATED CIRCUIT COMPRISING A CLOCK TREE

L'invention concerne un circuit intégré comprenant : • un premier caisson (60) semi-conducteur ; • une pluralité de cellules standard (66), chaque cellule standard comportant un premier transistor à effet de champ de technologie FDSOI comprenant un premier plan de masse semi-conducteur, situé immédiatement sur le premier caisson ;ne cellule d'arbre d'horloge (30), contiguë à des cellules standard, la cellule d'arbre d'horloge comportant un second transistor à effet de champ de technologie FDSOI lequel comporte un second plan de masse semi-conducteur situé immédiatement sur le premier caisson (60), de manière à former une jonction p-n avec ce premier caisson. Le circuit intégré comporte un réseau d'alimentation (51) électrique apte à appliquer des polarisations électriques distinctes directement sur les premier et second plans de masse.

SHOCK ABSORBING DEVICE FOR A SAWING MACHINE

COMPRISING A CELL INTEGRATED CIRCUIT CLOCK TREE

DOMESTIC TERMINATION DEVICE WITH COMMON DISCONNECTION/CONNECTION MEANS

METHOD FOR MONITORING AN EQUIPMENT TYPE ELECTROMECHANICAL ACTUATOR

Procédé de surveillance d'un équipement de type actionneur électromécanique, l'équipement comportant un moteur électrique triphasé, le procédé de surveillances comprenant les étapes : - de réaliser des mesures de courants triphasés qui alimentent le moteur électrique triphasé ; - de projeter dans un repère de Park les mesures de courants triphasés (Iq) ; - de mettre en œuvre, sur le courant en quadrature, une méthode de décomposition modale empirique ensembliste (30) couplée à une méthode de séparation aveugle de source (40), pour obtenir des composantes sources (IC,..., IC10) ; - de sélectionner automatiquement parmi les composantes sources un premier ensemble de composantes sources (IC1,... IC9) sensibles à un premier défaut et un deuxième ensemble de composantes sources (IC9) sensibles à un deuxième défaut ; - de construire (60) un premier signal virtuel de défaut et un deuxième signal virtuel de défaut ; - d'extraire (70) du premier signal virtuel de défaut un premier ensemble de signatures ...

DETECTION DEVICE USING HORIZONTAL PLANE AND OBSTACLE DETECTION METHOD USING SUCH A DEVICE

OPHTHALMIC LENS, ESPECIALLY FOR SUNGLASSES

FLAT PANEL DISPLAY HAS LIQUID CRYSTAL FUNCTIONING IN REFLECTIVE MODE AND ITS PROCESS DEREALISATION

SECURE MOTOR HINGE FOR A CHARACTER HUMANOID ROBOT HAS

L'invention concerne une articulation motorisée sécurisée destinée à être montée entre un premier et un second membres d'un robot à caractère humanoïde, caractérisée en ce qu'elle comprend : • un moteur (21) comprenant une partie fixe (25) destinée à être relié au premier membre, et une partie mobile (26) pouvant être entrainée en mouvement par rapport à la partie fixe (25) et destinée à être relié au second membre par rapport au premier membre, • un frein (22) capable d'exercer un effort sur la partie mobile (26) du moteur (21) par effet ressort, pour empêcher le mouvement de la partie mobile (26) par rapport à la partie fixe (25), • un actionneur (23) capable de déplacer le frein (22) en s'opposant à l'effet ressort, de sorte à libérer la partie mobile (26) du moteur (25) de l'effort du frein (22) et permettre au moteur (21) d'entrainer en mouvement la partie mobile (26) par rapport à la partie fixe (25).

COMPRISING A CELL INTEGRATED CIRCUIT CLOCK TREE

CELL OF RANDOM ACCESS MEMORY SRAM HAS TEN TRANSISTORS

L'invention concerne un dispositif et un procédé de commande d'un dispositif mémoire de type SRAM, comprenant : un circuit bistable et deux circuits de commutation reliant respectivement deux bornes d'accès du circuit bistable à deux lignes de bits complémentaires, chaque circuit de commutation comportant : un premier interrupteur (40G, 40D), un deuxième interrupteur (44G, 44D) en série entre une des lignes de bits et une desdites bornes d'accès, et un troisième interrupteur (46G, 46D) entre le point milieu de ladite association en série et une borne d'application d'un potentiel de référence, une borne de commande du troisième interrupteur étant reliée à l'autre desdites bornes d'accès.

CIRCUIT PRINTS INTENDS TO ENSURE the CONNECTION Of an ELECTRICAL MOTOR AND ELECTRICAL MOTOR INCLUDING/UNDERSTANDING the CIRCUIT PRINTS

L'invention concerne un moteur électrique et un circuit imprimé destiné à assurer le raccordement électrique du moteur. Le circuit imprimé comprend : • une partie centrale (11) destinée à recouvrir une première face (45) du moteur électrique, • des languettes souples (12) prolongeant la partie centrale (11) et destinées à recouvrir en partie une seconde face du moteur et à être raccordées électriquement avec cette seconde face, • une première paire de plots (13a, 13b) destinés à recevoir des connexions provenant du moteur, • une seconde paire de plots (14a, 14b) destinés à recevoir des fils d'alimentation du moteur, • des pistes (15a, 15b) raccordant chacune un plot de la première paire (1 3a, 1 3b) avec un plot de la seconde paire (1 4a, 1 4b), • un condensateur de filtrage (18) raccordé entre les pistes (1 5a, 1 5b), • un plan de masse (19) recouvrant la majeure partie de la partie centrale (11) et les languettes souples (12), le plan de masse (19) étant destiné à être raccordé électriquement ...

METHOD FOR MONITORING AN EQUIPMENT TYPE ELECTROMECHANICAL ACTUATOR

L'invention concerne un procédé de surveillance comportant une phase de diagnostic pour évaluer un état d'un équipement, la phase de diagnostic comprenant : - une étape d'apprentissage comportant : - une première sous-étape d'apprentissage et de réglage d'un algorithme SVM selon une logique classique pour générer un modèle d'apprentissage net de classification des observations (50) ; - une première sous-étape d'apprentissage et de réglage d'un algorithme SVM selon une logique floue pour générer un modèle d'apprentissage flou de classification des observations (51) ; - une sous-étape de paramétrage d'une règle de décision automatique au moyen du modèle d'apprentissage net et du modèle d'apprentissage flou (52) ; - une étape de diagnostic en opération consistant à acquérir en opération et à classifier de nouvelles observations.

Control system for determining and locating possible defects in suspension of car adapted to contact with ground by wheels, has processing unit delivering exploitable information to determine and locate defects in suspension at its exit

La présente invention concerne les systèmes de contrôle pour déterminer et localiser des éventuels défauts dans la suspension Sop d'un véhicule Ve comportant un châssis Cha, un moteur Mo et quatre bras de suspension des roues Er. Le système est essentiellement caractérisé par le fait qu'il comporte quatre capteurs de mesure de distance 11, 12, 13, 14 respectivement disposés en quatre points 111, 112, 113, 114 du châssis Cha, respectivement à proximité et au droit des quatre bras de suspension des roues Er, chaque capteur 11, 12, 13, 14 étant apte à délivrer à sa sortie un signal fonction de la distance qui le sépare du sol, et un organe de traitement 20 programmable avec un logiciel donné dont quatre entrées sont respectivement connectées aux sorties des quatre capteurs 11, 12, 13, 14, l'organe de traitement 20 étant apte à délivrer à sa sortie des informations exploitables pour déterminer et localiser des éventuels défauts dans la suspension en fonction des variations des quatre premiers ...

CONNECTION MODULE

Module de raccordement (27) à une ligne de communication (11) comprenant une prise de raccordement (43) à un boitier de conversion (21), un organe de connexion entrant (37) agencé pour être connecté à au moins deux éléments unitaires entrants (39) de la ligne de communication (11), un organe de connexion sortant (41) agencé pour être connecté à au moins deux éléments unitaires sortants (42) de la ligne de communication (11) et chaque élément unitaire sortant (42) correspondant à un élément unitaire entrant (39), un contact entre les éléments unitaires entrants (39) et les éléments unitaires sortants (42) assurant la continuité de ladite ligne de communication (11). Le module de raccordement (27) comprenant en outre un élément de bascule (45) agencé pour, en une configuration passante, mettre en contact chaque élément unitaire entrant (39) à l'élément unitaire sortant (42) correspondant, et pour, en une configuration commutée, mettre en contact chaque élément unitaire sortant (42) à une ...

Flip-flop type latch for integrated circuit chip, has interlocking clusters, each with set of redundant data storage nodes, and buffer circuits, each with writing circuits for separately writing data in each storage node

Cette bascule protégée contre des pics de courant ou de tension comprend une première porte (P1) de transfert de données recevant, en entrée, des données d'entrée (D, DN) de la bascule, une première cellule de verrouillage maître (C1) raccordée en sortie de la première porte de transfert, une deuxième cellule de verrouillage esclave et une deuxième porte de transfert de données disposée entre les première et deuxième cellules de verrouillage, chaque cellule de verrouillage comprenant un ensemble de noeuds de stockage de données redondants. Les portes de transfert comprennent chacune des moyens (C' 1, C'2, C'3, C'4) pour écrire séparément des données dans chaque noeud de stockage.

SYSTEM Of RECORDING Of INFORMATION AND PROCESS Of USE Of a TELSYSTEME

METHOD FOR REALIZATION Of a MATRIX OF CHEMICAL SEQUENCES OF MOLECULES OUBIOLOGIQUES FOR DEVICE Of CHEMICAL OR BIOLOGICAL ANALYSIS

MASK VISION

METHOD AND DEVICE FOR MONITORING A CRITICAL PATH OF AN INTEGRATED CIRCUIT

COIL HAS RADIAL DAMPING

POWERED BIPEDAL ROBOT HAS CHARACTER

L'invention concerne un robot à caractère humanoïde motorisé (50) ayant un axe de positionnement (11) s'étendant selon un axe de référence (12) dans une position de référence et apte à se déplacer sur un plan horizontal (13), comprenant une première (14) et une seconde roues (15) en contact avec le plan horizontal (13). Selon l'invention, le robot (50) comprend une base (17) ayant une surface gauche (18) qui, dans un plan vertical passant par le centre des roues (14, 15), s'étend de part et d'autre de chacune des roues (14, 15), la surface gauche (18) étant apte à former en tout point de la surface gauche (18) un premier point de contact avec le plan horizontal (13), définissant pour tout premier point de contact un centre de rotation (O), et en ce que le robot (50) est configuré de façon à ce que le centre de rotation (O) et le centre de gravité (G) du robot (50) sont décalés de façon à générer un couple tendant à ramener le robot (50) depuis toute position dans laquelle son axe de positionnement ...

INSERT MOLDED HUB

GENERATOR Of IMPULSES.

JUNCTION BOX OF A TRANSMISSION ELEMENT OF A SIGNAL

Boitier de raccordement (1) d'un élément de transmission (21) d'un signal tel qu'un câble optique, le boitier de raccordement (1) comprenant une entrée (23), une sortie (25) ménagée dans la paroi du boitier de raccordement (1), une portion externe de la paroi du boitier de raccordement (1) agencée pour être mobile entre une position ouverte et une position fermée, une portion interne (17) de la paroi du boitier de raccordement (1) agencée pour être mobile entre une position escamotée et une position déployée. La paroi interne (17) présente une première face et une deuxième face (17b) opposée à la première face, au moins un motif (31) agencé pour coopérer avec un élément interne au boitier de raccordement (1), ledit motif (31) étant ménagé dans ou rapporté sur la première face et/ou la deuxième face (17b).

BASIC CELL Of an INTEGRATED CIRCUIT NOT VERY SENSITIVE TO the EXTERNAL DISTURBANCES

L'invention concerne un circuit électronique intégré comprenant des éléments assurant la réalisation d'une fonction logique et des moyens d'atténuation de la sensibilité desdits éléments vis-à-vis de perturbations extérieures, lesdits moyens d'atténuation étant déconnectables lors de phases de modifications volontaires de l'état desdits éléments.

DEVICE REPORT

L'invention concerne un dispositif mémoire comprenant des premier et second inverseurs (102, 104) intercouplés entre des premier et second noeuds (106, 108), le premier inverseur étant adapté à être alimenté par une première tension d'alimentation (VDD, GND) par l'intermédiaire d'un premier transistor (202) et le second inverseur étant adapté à être alimenté par la première tension d'alimentation par l'intermédiaire d'un second transistor (204) ; un premier circuit de commande (206) adapté à commander la grille (210) du premier transistor en fonction de la tension sur le second nœud (108) et sur la grille (220) du second transistor ; et un second circuit de commande (208) adapté à commander la grille (220) du second transistor en fonction de la tension sur le premier nœud (106) et sur la grille du premier transistor.

DEVICE OF CATCH IN ELECTRIC CURRENT ON AN OVERHEAD LINE

BASIS FOR RECHARGING A BATTERY AND RECHARGING METHOD USING SUCH A BASE

CARROUSEL HAS ELECTRONIC CHIPS

SYSTEM Of ACQUISITION AND TREATMENT Of RELATIVE INFORMATIONS HAS a GOOD OUSERVICE LOCATES BY a COMPRISING CODE OF the RELATIVE INFORMATIONS TO THAT GOOD OUSERVICE AND USE OF THIS SYSTEM

PROCESS IMPROVES OF REALIZATION Of ENCLOSURES FILLED WITH LIQUID AND FERMEES BY a MEMBRANE

COIL HAS DAMPING PROPERTIES

MASK VISION

L'invention concerne un écran de vision dont la surface convexe (2) est continue, cylindrique, torique ou sphérique dont la trace dans le plan de vision binoculaire est un arc de cercle extérieur de rayon (R) déterminé, caractérisé en ce que la trace de la surface concave (3,4) de cet écran dans ce même plan de vision, est formée au moins dans la région de chaque axe de vision (AD, AG) d'un arc de cercle (3,4) intérieur, de centre (C1,C2) différent de celui de l'arc de cercle croisé par l'autre axe de vision.

ACTUATING A HAND FOR INTERRUPTING THE BIPEDAL ROBOT HAS CHARACTER

L'invention concerne une main destinée à équiper un robot à caractère humanoïde. La main (10) comprend une paume (11) et plusieurs doigts (13, 14, 15, 16, 17) motorisés par rapport à la paume (11), Selon l'invention, la main (10) comprend un actionneur (101, 102) commun à plusieurs doigts (14, 15, 16, 17) et un palonnier (103, 104) permettant de répartir un effort exercé par l'actionneur (101, 102) vers les doigts (14, 15, 16, 17).

METHOD FOR MANAGING THE OPERATION OF A REDUNDANT CIRCUIT HAS MAJORITY VOTE AND ASSOCIATED DEVICE

TERMINAL BOX WITH RACK PROVIDED WITH ENTRANCE AND EXIT RAMPS

Coffret de raccordement d'un élément de transmission d'un signal tel qu'un câble optique, l'élément de transmission étant pourvu d'une pluralité d'éléments unitaires tels que des fibres optiques, le coffret de raccordement comprenant un boitier de raccordement pourvu d'une base (7) et d'un couvercle, un plateau de raccordement (5) présentant une face rangement et une face de distribution (25) pour la pluralité d'éléments unitaires, un logement de réception (29) agencé pour recevoir une prise de raccordement externe (21), le plateau de raccordement (5) présentant en outre une rampe d'entrée (69) et une rampe de sortie (71) pour la pluralité d'éléments unitaires, la rampe d'entrée (69) et la rampe de sortie (71) étant ménagées dans la face de rangement de manière à présenter chacune une inclinaison par rapport à un plan d'extension de la face de rangement et s'étendant au-delà d'un plan d'extension de la face de distribution (25).

HAND FOR INTERRUPTING THE ROBOT HAS IMPROVED FINGER BIPEDAL CHARACTER

L'invention concerne une main destinée à équiper un robot à caractère humanoïde. La main comprend une paume et au moins un doigt (14) articulé à la paume, le doigt (14) comprenant au moins une phalange (21, 22, 23) et une articulation (27, 28, 29) reliant la phalange (21, 22, 23) à la paume, la phalange (21, 22, 23) s'étendant selon une direction principale (31, 32, 33). Selon l'invention, l'articulation (27, 28, 29) comprend une pièce de jonction (35, 36, 37) élastique permettant plusieurs degrés de libertés. La main comprend des moyens de motorisation (50, 51) d'un degré de liberté en rotation parmi les degrés de liberté rendus possibles par la pièce de jonction (35, 36, 37), le degré de liberté en rotation motorisé permettant un mouvement relatif autour d'un axe (41, 42, 43) perpendiculaire à la direction principale (31, 32, 33) de la phalange (21, 22, 23). Les autres degrés de liberté parmi les degrés de liberté rendus possibles par la pièce de jonction (35, 36, 37) ne sont pas motorisés ...

COMPOSE 8-OXO-9- [3 (1H-BENZIMIDAZOL-2-YLOXY) - PHENYL] - 4,5,6,7,8,9-HEXAHYDRO-2H-PYRROLO [3,4-B] QUINOLINE-3-CARBOXYLATE Of ETHYL, SALT, CRYSTALLINE FORM, CO-CRISTAL, FORMULATION, METHOD OF PREPARATION, APPLICATION AS DRUGS, COMPOSITIONS PHARMACEUTICAL AND NEW USE IN PARTICULAR AS INHIBITOR OF KINASES AURORA.

L'invention se rapporte plus précisément à un nouveau sel, co-cristal et formulations du 8-oxo-9-[3-(1 H-benzimidazol-2-yloxy)-phényl]-4,5,6,7,8,9-hexahydro-2H-pyrrolo[3,4-b]quinoline-3-carboxylate d'éthyle de formule (F) : à leurs préparations et leur utilisation en thérapeutique, notamment comme inhibiteurs sélectifs des kinases Aurora A et B, et pour leur utilisation en tant qu'anti cancéreux.

DEVICE OF LONGITUDINAL CUTTING Of a TUBE

SHOCK ABSORBING DEVICE FOR A MOTOR VEHICLE

L'invention porte sur un dispositif amortisseur de chocs pour un robot humanoïde, comprenant une structure rigide reliée au robot humanoïde, une coquille extérieure déformable (21 ; 23), et un amortisseur (22 ; 24) ; l'amortisseur (22 ; 24) étant constitué d'une structure alvéolaire souple comprenant un ensemble d'alvéoles débouchantes selon une direction principale (X), et étant solidaire de la structure rigide (20) en une première extrémité selon la direction principale (X), et relié à la coquille extérieure déformable (21 ; 23) en une seconde extrémité opposée à la première selon la direction principale (X). Avantageusement, la coquille extérieure (21) est également reliée directement à la structure rigide au moyen d'au moins une fixation absorbante de type silentbloc. L'invention porte également sur un robot humanoïde, et en particulier la tête d'un robot humanoïde, comprenant un tel dispositif amortisseur de chocs.

Fabrication of decorative facing involves molding a self-setting fluid material to confer a given texture and/or color to the outer surface of the facing, for masonry or sculptural applications

Procédé de fabrication de parement décoratif de panneau ou de pièce en béton ou mortier par moulage, caractérisé en ce qu'il comporte au moins : une étape de remplissage d'un moule avec un matériau fluide susceptible de se solidifier destiné à donner l'état final de texture et/ ou de couleur de la surface extérieure du parement, une étape de solidification, et une étape d'acidage, après démoulage, de la surface dudit panneau ou de ladite pièce. Dans ledit procédé le matériau fluide susceptible de se solidifier destiné à donner l'état final de texture de la surface extérieure du parement comprend au moins un matériau non calcaire choisi parmi les oxydes métalliques, les corindons ou les carbures, comme les carbures de silicium, les oxydes de chrome, les oxydes de fer, de cobalt ou de titane.

PROCEEDED WITH PROTECTION Of a LOGICAL CIRCUIT AGAINST EXTERNAL RADIATIONS AND ELECTRONIC DEVICE ASSOCIATES.

Procédé de protection d'un bloc logique (A0) contre des radiations externes, ledit circuit électronique (A0) comportant au moins une sortie. On effectue au moins une duplication du circuit électronique (A0), la duplication étant une duplication au moins fonctionnelle du circuit électronique (A0), et on relie respectivement les sorties des circuit électronique (A0, A1) à des entrées homologues d'éléments combinatoires ou séquentiels (21, 22) au moins fonctionnellement identiques, et on relie ensemble les sorties (S) homologues de tous les éléments combinatoires ou séquentiels (21, 22).

METHOD FOR REALIZATION Of a VIEWING SCREEN INSERT HAS MOULDS BY INJECTION

L'invention concerne un procédé de réalisation d'un écran de vision (3) à insert (9) surmoulé par injection, comprenant les étapes de : - disposer un insert (9) à surmouler dans un moule d'injection (1), - maintenir l'insert (9) par au moins une buse d'aspiration (21) intégré dans le moule d'injection (1), - injecter dans le moule (1) une matière thermoplastique pour former une couche de support mécanique de l'écran de vision, - démouler l'écran de vision (3) ainsi formée ...

BASE FOR RECHARGING A BATTERY AND RECHARGING METHOD USING SUCH A BASE

L'invention concerne un ensemble de rechargement comprenant un véhicule mobile et une base (200) de rechargement de forme complémentaire au véhicule mobile et apte à réceptionner le véhicule mobile et destinée à recharger une batterie d'un véhicule mobile comprenant au moins une roue (50, 51, 52), la base (200) étant connectable à une source électrique, caractérisé en ce que la base (200) comprend : • une surface de réception (210) et un plan socle (220) destiné à être posé sur un plan de référence (230), la surface de réception (210) et le plan socle (220) de la base (200) formant un angle aigu (240), • une cavité hémisphérique (250) réalisée en creux dans la surface de réception (210) et destinée à recevoir la au moins une roue (50, 51, 52), • au moins un connecteur électrique (260) disposé de façon à permettre la connexion de la base (200) avec la batterie lors de la descente de la au moins une roue (50, 51, 52) dans la cavité hémisphérique (250). L'invention concerne également un procédé ...

CONTROL METHOD OF AN INTEGRATED CIRCUIT

METHOD FOR PRODUCING POLARIZING LENSES, AND THE POLARIZING LENS OBTAINED BY SAID METHOD

NEW ALKYLTHIOETHERS, THEIR PREPARATION AND THEIR APPLICATION INTO THERAPEUTIC

La présente invention a pour objet des nouveaux alkylthioéthers pour la préparation d'un médicament destiné à prévenir ou à traiter un désordre dû à un dysfonctionnement des glandes sébacées chez l'homme ou l'animal. Les composés selon la présente invention exercent une forte inhibition de l'Acyl CoA: cholestérol O - Acyl transférase (ACAT).

Interior termination device for use in phone network, has electrical zone of contact that is connected/disconnected from another electrical zone of contact, and electrical connection units are respectively connected to zones of contact

La présente invention a pour objet un dispositif de terminaison intérieur (1) d'un logement comprenant au moins une pluralité de prises de test (T1, RJ2) formant au moins un ensemble (100) de prises de test, chacune des prises de test (T1, RJ2) de l'au moins un ensemble (100) de prises de test comprenant des moyens de connexion/déconnexion électrique (C, C') agencés pour permettre ou interrompre la communication du flux entre les premiers moyens de raccordement (RAC1) et les deuxièmes moyens de raccordement (RAC2), ledit dispositif de terminaison intérieur (1) étant caractérisé en ce que les moyens de connexion/déconnexion (C, C') d'une première prise de test (T1) et les moyens de connexion/déconnexion (C, C') d'une deuxième prise de test (RJ2) comprennent en commun au moins une première zone de contact électrique (21) et au moins une deuxième zone de contact électrique (22), la première zone de contact électrique (21) étant agencée pour être connectée/déconnectée de la deuxième zone de ...

DETECTION DEVICE CROISES PLANES OF AN OBSTACLE AND DETECTION METHOD USING SUCH A DEVICE

Radiation-hardened CMOS logic device

L'invention concerne un dispositif logique durci vis à vis des rayonnements comprenant : un premier transistor à canal n (206) couplé par ses nœuds conducteurs principaux entre un noeud de sortie (Z) d'un dispositif logique (202) et un rail d'alimentation en tension (VDD) ; et un premier transistor à canal p (208) couplé par ses nœuds conducteurs principaux entre le noeud de sortie (Z) du dispositif logique (202) et un rail de tension de référence, dans lequel les grilles du premier transistor à canal n et du transistor à canal p (206, 208) sont couplées au noeud de sortie (Z).

DEVICE FOR GENERATING A CLOCK SIGNAL BY FREQUENCY MULTIPLICATION

Dispositif de génération d'un signal impulsionnel, comprenant une entrée pour recevoir un signal impulsionnel initial (CKin) ayant une période initiale (Tin), un oscillateur (11) configuré pour générer au moins un signal d'oscillateur (CKRO), un premier étage (12) synchronisé avec ledit au moins un signal d'oscillateur et configuré pour délivrer un signal impulsionnel secondaire (PS) dont l'espace entre deux impulsions successives est représentatif de la partie entière d'une division de la période initiale (Tin) par un entier N et un signal auxiliaire (DLY) représentatif de la partie fractionnaire de ladite division et contenant, pour chaque impulsion du signal impulsionnel secondaire (PS), une indication d'un décalage temporel à appliquer sur ladite impulsion compte tenu de l'espace entre ladite impulsion et l'impulsion précédente, et un deuxième étage (13) configuré pour recevoir les impulsions successives du signal secondaire et les indications de décalage correspondantes et pour élaborer ...

OPTICAL ELEMENT POLARIZING DYED AND MANUFACTORING PROCESS Of SUCH an ELEMENT

L'invention concerne élément optique polarisant teinté (1), comprenant un ensemble polarisant (5) composé d'au moins d'une première (7) et d'une seconde (9) couches d'un matériau thermoplastique ou thermodurcis sable prenant en sandwich un film polarisant (11) et un procédé de fabrication de cet élément optique. Ce dernier comporte en outre une troisième couche (13) d'un matériau thermoplastique teinté adhérant par injection à la seconde (9) couche et en ce qu'il comprend une quatrième couche (15) d'un matériau thermoplastique cristal adhérant par injection à la troisième couche (13), destinée à être surfacée pour un effet correcteur.

PRESSURE PICK-UP HAS MEMBRANE COMPRISING OF CARBIDE OF SILICON AND PROCEDEDE MANUFACTURE

PROCESS OF ADAPTIVE FORMATION OF BEAMS FOR A RADAR OF MONITORING OF THE GROUND, AND RADAR IMPLEMENTING THE PROCESS

NEW DERIVATIVES BENZIMIDAZOLES AND BENZOTHIAZOLES, THEIR PREPARATION AND THEIR PHARMACEUTICAL USE IN PARTICULAR AS INHIBITORS DE CMet

DETECTION DEVICE OBLIQUE PLANE AND OBSTACLE DETECTION METHOD USING SUCH A DEVICE

L'invention concerne un dispositif de détection (10) d'obstacles destiné à équiper un véhicule mobile (11) ayant un sens de déplacement privilégié dans un premier sens selon un axe X parallèlement à un plan de référence (12), caractérisé en ce qu'il comprend : • un émetteur dit pelle (32) d'un faisceau électromagnétique dit pelle (27) s'étendant dans un plan virtuel dit pelle (26) configuré pour s'intersecter avec le plan de référence (12) selon une droite perpendiculaire à l'axe X, • un premier capteur d'image (5) apte à produire une image de la droite, • un moyen d'analyse d'image apte à déterminer la présence d'un obstacle par détection d'une déformation de la droite. L'invention concerne également un procédé de détection mettant en œuvre un tel dispositif.

METHOD FOR REALIZATION OF POLARIZING LENSES, AND THE POLARIZING LENS OBTAINED BY THE AFOREMENTIONED PROCESS

Lentille polarisante constituée, successivement, d'une couche de support mécanique en polyamide, une couche intermédiaire d'alcool polyvinylique et une couche externe en triacétate de cellulose. Procédé de fabrication d'une telle lentille.

CELL INTEGRATED CIRCUIT COMPRISING A CLOCK TREE

L'invention concerne un circuit intégré, comprenant -un bloc comportant comportant : • un premier (38) et un second (40) caissons semi-conducteurs de dopages opposés ; • des cellules standard (42, 43), placées les unes à côté des autres, chaque cellule standard (42) comportant des premiers transistors (60, 62);une cellule d'arbre d'horloge (30), entourée par les cellules standard, la cellule d'arbre d'horloge (30) comportant : - un troisième caisson semi-conducteur (104), présentant un dopage de même type que le dopage du premier caisson (38) ; - des seconds transistors (100, 102); - une bande semi-conductrice (106), s'étendant continûment autour du troisième caisson (104) et présentant un dopage de type opposé au dopage du troisième caisson, pour isoler électriquement le troisième caisson (104) du premier caisson (38).

MOBILE ROBOT POWERED MASTER

L'invention concerne un robot mobile maître motorisé (1) comprenant: - au moins un capteur d'environnement (5, 6, 7, 8) configuré pour acquérir des informations représentatives d'au moins une partie de l'environnement du robot mobile maître motorisé (1); - au moins une interface d'entrée (10a) configurée pour recevoir des instructions d'un utilisateur; - une unité de traitement (9) configurée pour déterminer des instructions représentatives d'au moins un comportement à exécuter par le robot mobile maître motorisé (1) en réponse à au moins une instruction de l'utilisateur et/ou une information représentative d'au moins une partie de l'environnement du robot mobile maître motorisé (1), et configurée pour déterminer au moins un comportement à exécuter par au moins un robot mobile esclave motorisé (2, 3, 4); et - au moins une interface de sortie (10b) configurée pour transmettre des instructions représentatives d'au moins un comportement à exécuter par au moins un robot mobile esclave motorisé ...

MANUFACTORING PROCESS OF THIN LAYERS ON A SPECIFIC SUPPORT AND UNEAPPLICATION

PROCESS OF HANDLING OF LAYERS SEMICONDUCTRICES FOR THEIR THINNING

STEER-BY-WIRE STEERING SYSTEM

TOGETHER FOR the GAS SUPPLY UNDER PRESSURE Of a SYSTEM INCLUDING/UNDERSTANDING a MOULD AND MANUFACTORING PROCESS Of a PRODUCT RESULTING From SUCH a MOULD

SPHERICAL WHEEL AND VEHICLE IMPLEMENTING THE WHEEL

L'invention concerne une roue sphérique (10) destinée à mouvoir un véhicule et à un véhicule mettant en œuvre la roue, la roue (10) étant motorisée en rotation par un arbre (12) pouvant tourner autour d'un axe (14). Selon l'invention, la roue(10) comprend deux calottes (15, 16) dont la surface suit la surface sphérique de la roue (12) et limitées chacune par un plan (17, 18). Les calottes (15, 16) sont articulées chacune au moyen d'une liaison pivot par rapport à l'arbre (12), un axe (21 , 22) de chacune des liaisons pivot étant perpendiculaire au plan (17, 18) de la calotte (15, 16) considérée. Les plans (17, 18) limitant les deux calottes (15, 16) sont sécants.

PROCESS AND DEVICE OF GUIDANCE Of a VEHICLE COMPARED TO an OVERHEAD LINE

La présente invention concerne les procédés pour guider un véhicule 10 sur une trajectoire virtuelle prédéfinie 20 sur un sol 30 par rapport à au moins une caténaire 40 placée en hauteur au-dessus du sol constituant une borne de la source d'alimentation en énergie électrique du véhicule 10, le véhicule étant relié à la caténaire au moyen d'une perche de prise de courant et comportant des moyens 14 pour commander sa direction de déplacement 16 sur le sol 30. Le procédé se caractérise par le fait qu'il consiste à mesurer la distance entre un premier point 18 du véhicule et la caténaire, cette distance ayant une valeur Vm, à déterminer la distance entre un second point 22 de la trajectoire virtuelle prédéfinie 20 et la caténaire 40, ce second point étant le point de la trajectoire virtuelle prédéfinie où devrait se trouver normalement un point référence 19 du véhicule en fonction d'au moins un paramètre prédéterminé lié au déplacement du véhicule, cette distance ayant une valeur Vo, à comparer ...

LIGHTING DEVICE

La présente invention appartient au domaine des dispositifs d'éclairage. Plus particulièrement la présente invention concerne un dispositif d'éclairage permettant d'éclairer uniformément une large surface avec une consommation électrique faible. La présente invention concerne également les techniques d'imageries utilisant le dispositif selon l'invention.

SYSTEM AND METHOD FOR COMMAND AND CONTROL OF AN APPARATUS CONTROLLABLE BY AN OPERATOR

L'invention concerne un système de commande et de contrôle d'un appareil pilotable par un opérateur, comprenant un terminal d'affichage (10) comprenant une pluralité d'emplacements d'affichage parmi lesquels un emplacement central, au moins un emplacement latéral droit et au moins un emplacement latéral gauche, apte à afficher des informations visuelles de commande de l'appareil au moins sur l'emplacement central et des informations visuelles de contrôle relatives à l'environnement de l'appareil sur au moins un des emplacements latéraux. Ce système comprend en outre un dispositif (18) de détection et de notification d'évènements ponctuels liés à l'environnement de l'appareil apte à commander l'affichage d'informations visuelles de contrôle. Ce système de contrôle et de commande est apte à acquérir des signaux électro-physiologiques permettant de mesurer une activité cérébrale de l'opérateur, et à traiter ces signaux électro-physiologiques pour déterminer, parmi les emplacements d'affichage ...

Radiating element for steric antenna, has active modules for forming directional beam adjustable in azimuth, and two horizontal cross dipoles supplied by power divider adjustable according to direction aimed by antenna

Cet élément rayonnant est à faisceau directif et orientable au lieu d'être omnidirectionnel. Il en résulte une grande diminution du rayonnement parasite capté en dehors de la direction de pointage de l'antenne stérique qui est une antenne réseau dont les éléments rayonnants sont distribués dans un volume. Comme montré sur la figure, l'élément rayonnant est avantageusement constitué de deux dipôles horizontaux croisés (10, 11) alimentés en parrallèle au moyen d'un répartiteur de puissance réglable (12) ...

MOBILE MOVEMENT COMBINES

L'invention concerne un mobile (60) pouvant se déplacer sur un plan horizontal (14) comprenant un corps (9) comprenant une zone de contact (17) sur le plan horizontal (14), une came (11) mobile en rotation par rapport au corps (9) autour d'un axe de came X, la came (11) présentant une surface de contact (12) avec le plan horizontal (14) lors de sa rotation. Selon l'invention, la surface de contact (12) de la came (11) comprend une première portion (15) et une seconde portion (16) distinctes, chacune de la première (15) et de la seconde (16) portions ayant un coefficient de frottement distinct, le coefficient de frottement de la première portion (15) étant supérieur au coefficient de frottement de la seconde portion (16), la première portion (15) étant configurée pour rouler sans glisser sur le plan horizontal (14), la seconde portion (16) étant configurée pour glisser sans rouler sur le plan horizontal (14), et en ce que le corps (9) est configuré pour faire une rotation par rapport au ...

METHOD AND DEVICE FOR CHECKING A CHAIN OF FLIP-FLOPS

Le procédé de test d'une chaîne de bascules (CB) comprend une génération d'un signal de référence (SR) à partir d'un motif de test (MOT) cycliquement rebouclé au rythme d'un signal d'horloge (SH), une propagation du signal de référence (SR) à travers la chaîne de bascules (CB) au rythme du signal d'horloge (SH) de façon à générer un signal de test (ST) en sortie de la chaîne (CB), une comparaison effectuée au rythme du signal d'horloge (SH) entre le signal de test (ST) et le signal de référence (SR) retardé d'un retard prenant en compte le nombre (N) de bascules de la chaîne (CB) et la longueur (K) du motif de test (MOT), et une génération d'un signal de sortie (SS) au rythme du signal d'horloge (SH) dont la valeur dépend du résultat de la comparaison.

CELL OF RANDOM ACCESS MEMORY SRAM HAS TEN TRANSISTORS

METHOD FOR MAKING A POLARIZING LENS AND CORRESPONDING POLARIZING LENS

SPHERICAL WHEEL FOR DRIVING A VEHICLE AND A VEHICLE WHEEL UTILIZING ŒUVRE

USE OF the 10-° (R3) - 1-AZABICYCLO°2.2.2! OCT-3-YLMETHYL! - 10HPHENOTHIAZINE FOR the PREPARATION Of a DRUG EXERTING a SELECTIVE INHIBITION OF RECEIVERS MUSCARINIQUES M1,2,3

CMOS LOGIC DEVICE CHARACTERISTICS AGAINST RADIATION CURED

WELL DRILLING

Procédé de décoration par sublimation consistant à placer l'objet (1) à décorer, de forme simple ou complexe, sur un support (2) et de le couvrir d'une feuille de transfert (3) comportant le motif sublimable, celle-ci étant plaquée contre l'objet (1) par l'intermédiaire d'une membrane souple (4) soumise et exposée à la fois à des moyens de dépression par vide d'air (5) et à des moyens de chauffage (6), pour permettre le transfert du décor sur l'objet (1), également soumis à température au moins en surface, caractérisé en ce que la membrane (4) est réalisée à partir d'une matière souple incorporant un composant métallique (7,7A), conducteur de la chaleur.

SECURITY CHARACTER HUMANOID ROBOT HAS

L'invention concerne un robot (10') à caractère humanoïde comprenant deux éléments (1, 2) et une articulation (20) à au moins un degré de liberté reliant les deux éléments (1, 2), l'articulation (20) permettant un débattement dans une plage donnée (α) en fonctionnement opérationnel, un premier (1) des deux éléments étant destiné à venir au contact d'une butée (22) appartenant à un second (2) des deux éléments en extrémité de la plage (α). Selon l'invention, le robot (10) comprend en outre au moins un interrupteur situé dans la butée (22). L'interrupteur est configuré pour actionner un contact électrique lorsqu'un effort exercé par le premier élément (1) contre la butée (22) dépasse un effort donné. The invention relates to a robot (10 ') with a humanoid character comprising two elements (1, 2) and an articulation (20) with at least one degree of freedom connecting the two elements (1, 2), the articulation (20) allowing a deflection in a given range (α) in operational operation, a first (1) of the two elements being intended to come into contact with a stop (22) belonging to a second (2) of the two elements at the end of the range (α). According to the invention, the robot (10) further comprises at least one switch located in the stop (22). The switch is configured to actuate an electrical contact when a force exerted by the first member (1) against the stop (22) exceeds a given effort.

NEW BENZOTHIAZOLES AND THEIR USE AS DRUGS

TETRAHYDRO-1H-PYRAZOLO [3,4-C] PYRIDINES SUBSTITUEES, COMPOSITIONS the CONTENANTET USE

THIENO (2,3-c) PYRAZOLES SUBSTITUTE, PROCEEDED OF PREPARATION, COMPOSITIONS the CONTAINER AND USE

ARRAY ANTENNA WITH TOTAL ELECTRON SCANNING

METHOD AND DEVICE FOR MONITORING A CRITICAL PATH OF AN INTEGRATED CIRCUIT

Le dispositif (DIS) de surveillance d'un chemin critique (CC) d'un circuit intégré (CIN), comprend une réplique du chemin critique (RCC) comportant au moins deux éléments séquentiels (ES1, ES2) mutuellement séparés par des moyens de retard programmables (MRP) à l'aide d'au moins un multiplexeur principal (MUXP1), des moyens de commande (MC) configurés pour commander ledit au moins un multiplexeur principal (MUXP1 à MUXP4) et un module de séquencement (MS) configuré pour séquencer chaque élément séquentiel (ES1, ES2) à partir d'un signal d'horloge principal (CLK). Le module de séquencement (MS) est configuré pour délivrer à partir du signal d'horloge principal (CLK) respectivement auxdits au moins deux éléments séquentiels (ES1, ES2), deux signaux d'horloge secondaires (SHS1, SHS2) mutuellement temporellement décalés de façon à prendre en compte au moins un temps de propagation inhérent audit au moins un multiplexeur principal (MUXP1 à MUXP4).

LIGHTING DEVICE

ANTI SYSTEM IS JAMMED IN A HUMANOID ROBOT HAS CHARACTER

L'invention concerne la sécurité d'utilisation d'un robot à caractère humanoïde. Le robot à caractère humanoïde comprend deux éléments (2, 3,) et une articulation (11) à au moins un degré de liberté reliant les deux éléments, les deux éléments comprenant chacun une peau (22, 23) délimitant leur surface externe, l'articulation (11) permettant un débattement dans une plage donnée, un premier des deux éléments (2, 3) étant destiné à venir sensiblement au contact d'une zone (25, 26) de la peau (22, 23) d'un second des deux éléments à une extrémité de la plage. Selon l'invention, la zone (25, 26) est souple de façon à permettre sa déformation d'une distance donnée avec un effort inférieur à un effort donné.

METHOD FOR POSITIONING AN OBJECT ON A SUPPORT

L'invention concerne un procédé de positionnement d'un objet sur un support par un utilisateur et un robot muni d'un capteur, d'un calculateur et d'un moyen de communication émetteur et un moyen de communication récepteur. Selon l'invention, le procédé comprend les étapes suivantes : - Communication d'un positionnement souhaité de l'objet sur le support par l'utilisateur au moyen de communication récepteur du robot, - Positionnement de l'objet sur le support par l'utilisateur, - Proposition d'ajustement du positionnement de l'objet par le moyen de communication émetteur du robot à l'utilisateur.

SPHERICAL WHEEL AND THE WHEEL SOCIETY

NEW DERIVATIVES ORGANOPHOSPHORES OF THE INDAZOLES AND THEIR USE COMMEMEDICAMENTS

PROCESS AND DEVICE ALLOWING TO CARRY OUT IN CONTINUOUS FLOW A THERMAL PROTOCOL DETRAITEMENT ON A SUBSTANCE

CASE SUPPORT MULTICHIP

PACKING OF PROTECTION AND CHOCK FOR OBJECTS HAS CIRCULAR CONTOUR

DOSAGE FORM INCLUDING/UNDERSTANDING OF (10 [(3S) - 1-AZABICYCLO [2.2.2] OCT-3-YLMETHYL] - 10H-PHENOTHIAZINE SE PRESENTING IN a SUITABLE FORM FOR the ADMINISTRATION Of UNDE PROPORTIONS DAY LABOURER RANGING BETWEEN 1 AND 3 MG

L'invention concerne une forme pharmaceutique comprenant du 10-[(3S)-1-azabicyclo[2.2.2]oct-3-ylméthyl]-10H-phénothiazine, ou au moins un de ses sels pharmaceutiquement acceptables, caractérisée en ce qu'elle se présente sous une forme appropriée pour l'administration orale d'une dose journalière comprise entre 1 et 3 mg, ainsi que son utilisation pour la préparation d'un médicament destiné à prévenir et/ou traiter les affections allergiques, en particulier la rhinite allergique.

ROCK HAS SINGLE PHASE Of CLOCK AND HAS REDUCED DYNAMIC POWER

TERMINAL BOX WITH RACK PROVIDED WITH ENTRANCE AND EXIT RAMPS

Network antenna with total electronic scanning, has radiating elements associated in pairs, where each pair of radiating elements is associated with single phase shifter module connected to two respective radiating elements of pair

Une antenne réseau à balayage électronique total (10) comportant une surface rayonnante (12), une pluralité d'éléments rayonnants (14) disposés sur la surface rayonnante (12), et des modules déphaseurs (16) propres à exciter les éléments rayonnants (14) pour former un faisceau d'émission de l'antenne réseau à balayage électronique total (10). Des éléments rayonnants (14) sont associés par paire(s) (26), à chaque paire (26) d'éléments rayonnants (14) étant associé un unique module déphaseur (16) respectif raccordé aux deux éléments rayonnants (14) de ladite paire (26).

USE OF the MEQUITAZINE IN the SHAPE OF RACEMATE OR ENANTIOMERS FOR the PREPARATION Of a DRUG INTENDS FOR the TREATMENT OR the PREVENTION OF PATHOLOGIES IMPLYING the HISTAMINIC RECEIVERS H4.

POWERED BIPEDAL ROBOT HAS CHARACTER

Control system Of an IN PARTICULAR OIL AND AIR SUSPENSION

Selective inhibitors of cb2 receptor expression and/or activity for the treatment of obesity and obesity-related disorders

The invention relates to a method for treating and/or preventing obesity and/or obesity-related disorders by administering to a subject in need thereof a selective inhibitor of cannabinoid type 2 (CB2) receptor expression.

Management of multiple software images with shared memory blocks

A data processing entity that includes a mass memory with a plurality of memory locations for storing memory blocks. Each of a plurality of software images includes a plurality of memory blocks with corresponding image addresses within the software image. The memory blocks of software images stored in boot locations of a current software image are relocated. The boot blocks of the current software image are stored into the corresponding boot locations. The data processing entity is booted from the boot blocks of the current software image in the corresponding boot locations, thereby loading the access function. Each request to access a selected memory block of the current software image is served by the access function, with the access function accessing the selected memory block in the associated memory location provided by the control structure.

ANTI-CANCER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

The invention relates to a compound of formula (I), more specifically in the levorotatory form (1) thereof, in particular the form having a rotatory power [α]D=−38.6+0.7 at a concentration of 0.698 mg/ml in methanol. The compound may be in the form of a base or an acid addition salt, in particular a pharmaceutically acceptable acid. The compound is a selective Aurora A and B kinase inhibitor and can be used as an anticancer drug. 2. The compound according to in levogyratory form.3. The compound according to claim 2 , exhibiting an optical rotation [α]=−38.6±0.7 at a concentration of 0.698 mg/ml in methanol.4. The compound according to claim 1 , in the form of a base or addition salt with an acid.5. A selective inhibitor of Aurora A and B kinases comprising the compound of .6. An anti-cancer agent comprising the compound of .7. (canceled)8. A pharmaceutical composition comprising the compound according to and at least one pharmaceutically acceptable excipient.9. (canceled)11. The process according to claim 10 , wherein the reaction between the three compounds is carried out in an alcohol at reflux.15. (canceled)16. A method of treating a cancer in a patient in need thereof comprising administering to said patient a therapeutically effective amount of the pharmaceutical composition of .17. The process according to claim 11 , wherein the alcohol is 1-butanol. The present invention relates to the compound of formula (I):and to the pharmaceutical composition comprising it. This compound is preferably the levogyratory compound (Ia). This compound can be used as an anti-cancer ingredient. The invention also relates to a process for preparing the compound (I) or (Ia) and also to some of the intermediates in said process.A number of cancer treatment strategies are aimed at inhibiting the Aurora-type kinases, particularly Aurora A and B, which are involved in the regulation of mitosis; in this regard, see 2004, 4, 927-9362002, 94, 13202002, 21, 61752009, 29(4), 1059-10712005, ...

Integrated Circuit Elementary Cell with a Low Sensitivity to External Disturbances

The present invention relates to an integrated electronic circuit including elements enabling to implement a logic function and means for attenuating the sensitivity of said elements to external disturbances, said attenuation means being disconnectable during phases of intentional modification of the state of said elements.

Exhaust gas sensor module

Described herein is a sensor module for sensing characteristics of a fluid flowing through a fluid conduit. The sensor module includes a sample probe with at least one sample arm that extends radially inwardly from a sidewall portion of the fluid conduit to a center portion of the fluid conduit, defines a fluid flow channel, and includes a plurality of inlet apertures. The sample probe also includes a sensor well that is located at a radially outer end of the at least one sample arm. The sensor well defines an interior volume that is in fluid communication with the fluid flow channel, an upstream portion closed to an first portion of the fluid conduit upstream of sensor well, and a discharge aperture open to a second portion of the fluid conduit downstream of the sensor well. The sensor module also includes a sensor positioned in the interior volume.

Tire, the Sidewalls of which are Reinforced with a Film of Multiaxially Stretched Thermoplastic Polymer

Tire comprising a crown surmounted by a tread, two sidewalls, two beads, each sidewall joining each bead to the crown, a carcass reinforcement anchored in each of the beads and extending into the sidewalls and into the crown, a belt extending into the crown circumferentially and located radially between the carcass reinforcement and the tread. At least one of its sidewalls is reinforced by a multiaxially stretched thermoplastic polymer film, positioned between and in contact with two layers of rubber composition, and on the outside with respect to the carcass reinforcement. Preferably, the thermoplastic polymer film has, irrespective of the tensile direction considered, a tensile modulus E which is greater than 500 MPa, a maximum tensile stress σwhich is greater than 80 MPa, and an elongation at break Ar greater than 40%. 1. A tire comprising a crown surmounted by a tread , two sidewalls , two beads , each sidewall joining each bead to the crown , a carcass reinforcement anchored in each of the beads and extending into the sidewalls and into the crown , a belt extending into the crown circumferentially and located radially between the carcass reinforcement and the tread , characterized in that at least one of its sidewalls is reinforced by a multiaxially stretched thermoplastic polymer film , positioned between and in contact with two layers of rubber composition , and located on the outside with respect to the carcass reinforcement.2. The tire according to claim 1 , wherein the rubber of each of the two layers of composition is a diene rubber.3. The tire according to claim 2 , wherein the diene rubber is selected from the group consisting of natural rubber claim 2 , synthetic polyisoprenes claim 2 , isoprene copolymers claim 2 , polybutadienes claim 2 , butadiene copolymers claim 2 , copolymers of dienes and of α-olefins claim 2 , and mixtures of such elastomers.4. The tire according to claim 3 , wherein each layer of rubber composition comprises from 50 to 100 phr ...

Tire with Thin Sidewalls and Improved Hooping Reinforcement

A tire ( 10 ) with a hooping reinforcement ( 100 ) including a part extending axially beyond a crown reinforcement that has NC intersections with any radial plane. A part ( 41 ) of the sidewall applied radially between an outer strip ( 120 ) and tread ( 30 ) is made of a rubber compound that has an elastic modulus E, and a mean thickness EA. The hooping reinforcement ( 100 ) is made of a textile material that has a shrinkage force at 180° C. (FC) that is less than or equal to 12 N. Elastic modulus E, mean thickness EA, number of intersections NC and the shrinkage force at 180° C. (FC) are chosen such that for each sidewall of the tire, the following inequality is satisfied: K = ( E · EA 2 · P B · NC · FC ) < 0.16 where P is the thickness of the tire measured in a direction perpendicular to the carcass reinforcement and having an intersection with the axial end of the outer layer of the crown reinforcement, and where B is the curvilinear length of the carcass reinforcement in said part ( 41 ) of the sidewall.

Aramid/polyketone composite textile cord

Aramid/polyketone composite textile cord comprising at least one aramid multifilament strand and at least one polyketone multifilament strand that are twisted together, the constituent individual filaments of the aramid multifilament strand being twisted according to a twist factor K 1 and the constituent individual filaments of the polyketone multifilament strand being twisted according to a twist factor K 2 , characterized in that in said cord: the aramid/polyketone weight ratio is greater than 1.5; the K 2 /K 1 ratio is greater than 1.10. This textile cord can advantageously be used as a reinforcer in tyres, in particular in the belt or in the carcass reinforcement of these tyres.

PROCESS FOR TREATING A REINFORCING ELEMENT HAVING A FLATTENED CROSS-SECTION

A reinforcing element, having a cross section with a flattened overall shape and extending in a main direction and comprising at least one lateral edge made of a polymeric composition comprising a thermoplastic polymer, the lateral edge extending in a general direction substantially parallel to the main direction is treated by heating at least a part of the lateral edge, during which at least a part of the lateral edge is subjected to a plasma flow so as to raise the temperature of the part of the lateral edge above the melting point of the thermoplastic polymer. 118.-. (canceled)19. A process for treating a reinforcing element having a cross-section with a flattened overall shape and extending in a main direction , and comprising at least one lateral edge made of a polymeric composition comprising a thermoplastic polymer , the lateral edge extending in a general direction substantially parallel to the main direction , the process comprising the step of:heating at least a part of the lateral edge, during which at least a part of the lateral edge is subjected to a plasma flow so as to raise the temperature of the part of the lateral edge above the melting point of the thermoplastic polymer.20. The process according to claim 19 , wherein the plasma flow is generated by means of a plasma torch.21. The process according to claim 19 , wherein the plasma is of the cold plasma type.22. The process according to claim 19 , wherein the plasma flow is generated from a gas comprising at least one oxidizing component.23. The process according to claim 22 , wherein the oxidizing component is selected from the group consisting of carbon dioxide claim 22 , carbon monoxide claim 22 , hydrogen sulphide claim 22 , carbon sulphide claim 22 , dioxygen claim 22 , nitrogen claim 22 , chlorine claim 22 , ammonia and mixtures thereof.24. The process according to claim 23 , wherein the oxidizing component is selected from the group consisting of dioxygen claim 23 , nitrogen and mixtures ...

Tire Including A Knitted Fabric

A tire that comprises a knit () comprising: columns (C C C C) of loops (B), the loops (B) of one and the same column (C C C C) being arranged one after the other substantially in an overall direction (X) referred to as the main direction; and rows (R R R R) of loops, the loops (B) of one and the same row (R R R R) being arranged one beside the other substantially in an overall direction (Z) referred to as the transverse direction. 1. A tire having at least one knit comprising:columns of loops, the loops of one and the same column being arranged one after the other substantially in an overall direction referred to as the main direction;rows of loops, the loops of one and the same row being arranged one beside the other substantially in an overall direction referred to as the transverse direction; andthe knit having, in the main overall direction and/or the transverse overall direction, a force at 100% elongation greater than or equal to 250 N, the force at 100% elongation being determined from a force-elongation curve obtained by applying standard ISO 13934-1:2013 to the knit embedded in a standard elastomer matrix.2. The tire according to the preceding claim 1 , wherein the knit has claim 1 , in the main overall direction and/or the transverse overall direction claim 1 , a force at 50% elongation greater than or equal to 170 N claim 1 , prcfcrably 300 N claim 1 , the force at 50% elongation being determined from a force-elongation curve obtained by applying standard ISO 13934-1:2013 to the knit embedded in the standard elastomer matrix.3. The tire according to claim 1 , wherein the knit has claim 1 , in the main overall direction and/or the transverse overall direction claim 1 , a maximum force greater than or equal to 800 N claim 1 , the maximum force being measured in accordance with standard ISO 13934-1:2013 applied to the knit embedded in the standard elastomer matrix.4. The tire according to claim 1 , wherein the knit has claim 1 , in the main overall direction ...

TYRE WITH LIGHTENED BELT STRUCTURE

Radial tyre, notably, for a passenger vehicle or van, with a lightened belt structure () comprising a multilayer composite laminate () of specific construction with a first layer () of rubber (C) comprising heat-shrinkable textile circumferential reinforcers () made of polyester, for example PET or PEN, this first layer radially (in the direction Z) surmounting two other layers () of rubber (C C respectively) reinforced with monofilaments () of high tensile steel; this multilayer composite laminate allows the weight and rolling resistance of the tyres to be reduced without impairing the cornering stiffness and, therefore, road holding and handling, while at the same time offering running endurance that is at least equivalent if not better. 116-. (canceled)17. A radial tyre comprising:a crown;a tread surmounting the crown;two beads;two sidewalls, each sidewall connecting a corresponding one of the beads to the crown;a carcass reinforcement anchored in each of the beads and extending in the sidewalls and the crown; anda belt extending in the crown in a circumferential direction (X) and situated radially between the carcass reinforcement and the tread, the belt including a multilayer composite laminate, on a side towards the tread, a first layer of rubber including a row of first reinforcers, which are oriented at an angle alpha of −5 to +5 degrees with respect to the circumferential direction (X), the first reinforcers being made of a heat-shrinkable textile material,', 'in contact with the first layer of rubber and arranged underneath the first layer of rubber, a second layer of rubber including a row of second reinforcers, which are oriented at an angle beta, the angle beta being positive or negative and having a value between 10 and 30 degrees with respect to the circumferential direction (X), the second reinforcers being metal reinforcers, and', 'in contact with the second layer of rubber and arranged underneath the second layer of rubber, a third layer of rubber ...

TYRE WITH LIGHTENED BELT STRUCTURE

A radial tyre, which is useable for a passenger vehicle or a van, has a crown reinforcement or belt having a lightened belt structure. The lightened belt structure is constructed of a multilayer composite laminate that includes a first layer of rubber that radially surmounts, in a direction Z, two other layers of rubber. The first layer of rubber includes weakly heat-shrinkable textile circumferential reinforcers, for example, made of nylon or polyester. The two other layers of rubber are reinforced with monofilaments of high tensile steel. The multilayer composite laminate allows the tyre's weight and rolling resistance to be reduced without impairing the tyre's cornering stiffness and, therefore, road holding and handling. At the same time, the multilayer composite laminate enables the tyre to have a running endurance that is at least equivalent if not better than that of a conventional tyre. 113-. (canceled)15. The tyre according to claim 14 , wherein the diameters D2 and D3 are each greater than 0.25 mm and less than 0.40 mm.16. The tyre according to claim 14 , wherein the diameter D1 is between 0.45 mm and 0.65 mm.17. The tyre according to claim 14 , wherein the density d1 is between 80 and 120 threads/dm.18. The tyre according to claim 14 , wherein the densities d2 and d3 are each between 130 and 170 threads/dm.19. The tyre according to claim 14 , wherein the thickness Ezis between 0.25 and 0.35 mm.20. The tyre according to claim 14 , wherein the thickness Ezis between 0.35 and 0.55 mm.21. The tyre according to claim 14 , wherein the thermal contraction CT is less than 3.5%.22. The tyre according to claim 14 , wherein{'br': None, 'i': Ez', 'Ez', '+D', 'D, 'sub': 1', '1, '0.225 Подробнее

REINFORCING ELEMENT HAVING A FLATTENED CROSS-SECTION

The reinforcing element () has a cross-section with a flattened overall shape having an aspect ratio greater than or equal to 5 and extending in a main direction (Z). It comprises a lateral edge () made of a polymeric composition comprising a thermoplastic polymer, the lateral edge () extending in a general direction substantially parallel to the main direction. The reinforcing element () is such that R=(Uc−U1)/Uc>11%, where Uc is the average value of the microhardness of the reinforcing element () measured in its central part, and U1 is the average value of the microhardness of the reinforcing element () measured at its lateral edge (). The lateral edge () does not have any ridges. 114.-. (canceled)15. A reinforcing element having a cross-section with a flattened overall shape having an aspect ratio greater than or equal to 5 and extending in a main direction and comprising at least one lateral edge made of a polymeric composition comprising a thermoplastic polymer , the lateral edge extending in a general direction substantially parallel to the main direction ,wherein, in a section plane substantially perpendicular to the main direction, the reinforcing element has a central point defined as the point of intersection between a first median plane of the width of the reinforcing element and a second median plane of the thickness of the reinforcing element, the first and second median planes being substantially perpendicular to one another and each first and second plane extending substantially parallel to the main direction, where Uc is the average value of the microhardness of the reinforcing element measured at the central point when the central point is made of the polymeric composition and at a point of the polymeric composition that is radially closest to the central point when the central point is not made of the polymeric composition, and', 'where U1 is the average value of the microhardness of the reinforcing element measured at a measuring point of the ...

Tire Including A Knitted Fabric Having Variable Properties

Tire () comprises a knit () comprising: columns of loops, the loops of one and the same column being arranged one after the other substantially in an overall direction referred to as the main direction and rows of said loops, the loops of one and the same row being arranged one beside the other substantially in an overall direction referred to as the transverse direction. The knit () comprises first and second zones (), each respectively having, at least in one of the main or transverse directions, a force FTand FSat 100% elongation that satisfies FS Подробнее

Anti-migration stent with quill filaments

A stent that includes a plurality of quill filaments. Each quill filament includes filament material, a surface, and a plurality of quills. Each quill has a tip, a body, and a base where the body extends from the base to the tip. The quill filaments can be interwoven to form the stent or the quill filaments can be engaged to the framework of a stent.

7xxx series aluminum alloy products in a stabilized t4 temper and methods of making the same

The present disclosure generally provides 7xxx series aluminum alloy products in a stable T4 temper. The disclosure also provides methods of making such products, for example, using processes that include a combination of casting, rolling, solutionizing, quenching, reheating, and slow cooling. The disclosure also provides various end uses of such products, such as in automotive, transportation, electronics, and industrial applications.

Secure, motor-driven hinge to be provided on a humanoid robot

A secured motorized articulation mounted between a first and a second limb of a humanoid-type robot, comprises: a motor comprising a fixed part linked to the first limb, and a mobile part that can be moved relative to the fixed part and linked to the second limb relative to the first limb, a brake capable of exerting a force on the mobile part of the motor by spring effect, to prevent the movement of the mobile part relative to the fixed part, an actuator capable of displacing the brake by opposing the spring effect, so as to release the mobile part of the motor from the force of the brake and allow the motor to move the mobile part relative to the fixed part.

Tire Reinforcing Ply

A passenger vehicle tire having hooping layer () that has a force at break FR per mm of axial width of the hooping layer at least equal to 35 daN/mm and has a secant extension modulus MA at least equal to 250 daN/mm, for an applied force F equal to 15% of FR. Working reinforcement () comprises a single working layer () the working reinforcers of which form, with the circumferential direction (YY′), an angle Aat least equal to 30° and at most equal to 50°. The carcass reinforcers of the at least one carcass layer () form, with the circumferential direction (YY′) and in the equatorial plane (XZ), an angle Aat least equal to 55° and at most equal to 80° and having an orientation opposite of that of angle Aof the working reinforcers so that the carcass reinforcers and the working reinforcers constitute a triangulation. 1. A fire for a passenger vehicle , comprising:a tread intended to come into contact with the ground and connected, at its axial ends, radially towards the inside, via two sidewalls, to two beads adapted to come into contact with a rim;{'sub': 'T', 'a working reinforcement, radially on the inside of the tread, and comprising at least one working layer comprising metal working reinforcers coated in an elastomeric material, said working reinforcers forming, with a circumferential direction of the tire, an angle Aat least equal to 10°;'}{'sub': 'F', 'a hoop reinforcement, radially on the inside of the tread, and radially adjacent to the working reinforcement, and comprising a single hooping layer comprising hoop reinforcers coated in an elastomeric material, the said hoop reinforcers forming, with the circumferential direction, an angle Aat most equal to 5°;'}{'sub': 'C1', 'a carcass reinforcement, joining the two beads together, radially on the inside of the working reinforcement and of the hoop reinforcement, and comprising at least one carcass layer comprising textile carcass reinforcers coated in an elastomeric material, said carcass reinforcers forming, ...

Tire Reinforcement

Hooping layer () of a passenger vehicle tire has a force at break FR per mm of axial width of the hooping layer at least equal to 35 daN/mm, an elongation at break AR at least equal to 5%, and a secant extension modulus MA at least equal to 250 daN/mm, for an applied force F equal to 15% of FR. Working reinforcement () comprises single working layer () the working reinforcers of which form, with circumferential direction (YY′), an angle Aat least equal to 30° and at most equal to 50°. The carcass reinforcers of at least one carcass layer () form, with circumferential direction (YY′) and in equatorial plane (XZ), angle Aat least equal to 55° and at most equal to 80° and having an orientation opposite to angle Aof the working reinforcers so that the carcass reinforcers and the working reinforcers constitute a triangulation. 1. A tire for a passenger vehicle , comprising:a tread intended to come into contact with the ground and connected, at its axial ends, radially towards the inside, via two sidewalls, to two beads intended to come into contact with a rim;{'sub': 'T', 'a working reinforcement, radially on the inside of the tread, and comprising at least one working layer comprising metal working reinforcers coated in an elastomeric material, the said working reinforcers forming, with a circumferential direction of the tire, an angle Aat least equal to 10°;'}{'sub': 'F', 'a hoop reinforcement, radially on the inside of the tread, and radially adjacent to the working reinforcement, and comprising a single hooping layer comprising hoop reinforcers coated in an elastomeric material, said hoop reinforcers forming, with the circumferential direction, an angle Aat most equal to 5°;'}{'sub': 'C1', 'a carcass reinforcement, joining the two beads together, radially on the inside of the working reinforcement and of the hoop reinforcement, and comprising at least one carcass layer comprising textile carcass reinforcers coated in an elastomeric material, said carcass reinforcers ...

Multilayer laminate which can be used for the reinforcement of a tyre belt

A multilayer laminate, which is usable as a reinforcing element for a finished article or for a semifinished product made of rubber, such as a tyre, includes at least one polymer film having, in any tensile direction in the film's plane, a Young's modulus that is greater than 500 MPa. The film is positioned between and in contact with two layers formed of a rubber composition, such as natural rubber. Each layer formed of the rubber composition exhibits, in a crosslinked state, a secant modulus that, in extension at 10% elongation, is greater than 30 MPa, with between 30 and 150 MPa being preferable for the secant modulus.

Method for producing annular parts and use of said method

The invention relates to a method for working a strip continuously supplied from a coil, using the same equipment for roll bending, cutting and welding in a single combined machine, such that an end product of the required quality is efficiently produced.

NOVEL CRYPTOPHYCIN COMPOUNDS AND CONJUGATES, THEIR PREPARATION AND THEIR THERAPEUTIC USE

The present invention relates to cryptophycin compounds of formula (I): 23-. (canceled)4. The Cryptophycin compound of formula (I) according to claim 1 , wherein:{'sub': 2', '3, 'each of Rand Rrepresents a hydrogen atom, or'}{'sub': 2', '3', '2', '3, 'one of Rand Rrepresents a methyl group and the other one represents a hydrogen atom, or Rand Rform together with the carbon atom to which they are attached a cyclopropyl group.'}56-. (canceled)7. The Cryptophycin compound of formula (I) according to claim 1 , wherein each of Rand Rrepresents a methyl group.8. (canceled)9. The Cryptophycin compound of formula (I) according to claim 1 , wherein Rand Rrepresent claim 1 , independently of each other claim 1 , a hydrogen atom or a (C-C)alkyl group.10. The Cryptophycin compound of formula (I) according to claim 1 , wherein Rrepresents two substituents selected from a methoxy group and a chlorine atom.1113-. (canceled)14. The Cryptophycin compound of formula (I) according to claim 1 , wherein W is selected from (C-C)alkyl-NHR claim 1 , (C-C)alkyl-OH claim 1 , (C-C)alkyl-SH and (C-C)alkyl-COH.15. The Cryptophycin compound of formula (I) according to claim 1 , wherein W represents a CH—NHor a CH—OH group.16. (canceled)18. (canceled)19. The Cryptophycin payload of formula (II) according to claim 17 , wherein Y represents (C-C)alkyl-NR.20. (canceled)2324-. (canceled)25. The Cryptophycin payload of formula (II) according to claim 21 , wherein L2 represents a (C-C)alkyl group or a (C-C)alkyl-(OCHCH)group or a CH(SOH)—(C-C)alkyl group.26. (canceled)28. (canceled)29. The Conjugate of formula (III) according to claim 27 , wherein RCG2 is selected from:ε-amino groups of lysines borne by the side chains of the lysine residues that are present at the surface of an antibody,α-amino groups of N-terminal amino acids of antibody heavy and light chains,saccharide groups of the hinge region,thiols of cysteines generated by reducing intra-chain disulfide bonds or the thiols of engineered ...

Assembly for charging a battery and charging method implementing such an assembly

A charging assembly includes an object comprising a battery and a plug intended to charge the battery, the plug being capable of being connected to an electricity source. The object comprises a base suitable for receiving the plug, comprising a first electrical connector, a first magnetic connector suitable for positioning the plug with respect to the base. The plug comprises a contact surface, the shape of which is complementary to a surface of the base, a second electrical connector positioned so as to come into contact with the first electrical connector in order to allow electrical contact between the first and second electrical connectors when the contact surface is positioned on the surface of the base, a second magnetic connector, positioned in proximity to the contact surface, attracting the first magnetic connector, so as to allow the first and second electrical connectors to be aligned and electrical contact to be maintained during the charging of the battery. One of the first and second electrical connectors is a surface connector and the other of the first and second electrical connectors is a point connector that is positioned so as to rest against the surface connector, for multiple separate orientations of the contact surface on the base.

Stent retrieval member and devices and methods for retrieving or repositioning a stent

An implantable stent includes a stent retrieval member for repositioning or retrieval of the stent after it has been implanted into a bodily lumen. The stent includes a distensible tubular stent having a tubular structure having a tubular wall defined by an interior surface and an exterior surface and having opposed open ends; and a stent retrieval member comprising an elongate member comprising a generally circular perimetric base and a shaped projection having first and second spaced apart members extending acutely or perpendicularly from the base and connected by an apical portion. Force exerted on the shaped projection causes contraction or expansion of the circular base. The circular base is securably attached to one of the open ends of the stent, and the shaped projection extends longitudinally beyond this open end of the stent.

Method and device for synthesizing an image of a face partially occluded

A method and device for synthesizing a first face in a first image, by determining a first occluded part of the first face that is occluded by an occluding object; determining a first visible part of the first face from the first occluded part; calculating first attributes representative of the first visible part; obtaining first parameters representative of an appearance of the first face by applying a regressor to the first attributes, the regressor modelling a correlation between second attributes representative of second visible parts of a plurality of second faces in second images and second parameters representative of an appearance model of the plurality of second faces; and synthesizing the first face using the first parameters.

PNEUMATIC TIRE COMPRISING REINFORCING ELEMENTS IN THE FORM OF MULTI-LAYER TAPES

Tire () comprising a carcass ply () that connects two beads () by way of two sidewalls (), said carcass ply () being surmounted radially on the outside by a crown reinforcing zone () comprising a plurality of reinforcing strips () disposed in at least two layers and coated in an elastomeric composition (), the mean overlap between the strips of the two layers being greater than 40%, the reinforcing strips () being made of a thermoplastic film having a modulus greater than 0.9 GPa and preferably greater than 2 GPa in the main direction and in the transverse direction. 110-. (canceled)11. A tire comprising:a carcass ply;two beads;two sidewalls;a tread; anda crown reinforcing zone,wherein the carcass ply connects the two beads by way of the two sidewalls,wherein the crown reinforcing zone is positioned radially external to the carcass ply and radially internal to the tread, the first layer is positioned radially internal to the second layer,', 'the reinforcing strips of the first layer and second layers are disposed in a substantially circumferential direction, with the reinforcing strips of the first layer being disposed in a staggered manner relative to the reinforcing strips of the second layer,, 'wherein the crown reinforcing zone includes a plurality of reinforcing strips disposed in at least a first layer and a second layer such thatwherein the reinforcing strips are coated in an elastomeric composition,wherein a mean overlap between the reinforcing strips of the first and second layers is greater than 40%, andwherein the reinforcing strips are made of a thermoplastic film having a modulus greater than 0.9 GPa in a main direction and in a transverse direction.12. The tire according to claim 11 , wherein the modulus of the thermoplastic film is greater than 2 GPa.13. The tire according to claim 11 , wherein an aspect ratio of the thermoplastic film is greater than or equal to 5.14. The tire according to claim 11 , wherein the thermoplastic film is made of:a ...

Ophthalmic Lens, In Particular For Sunglasses

The invention relates to an ophthalmic lens ( 1 ) comprising a substrate ( 13 ), said lens having a transmission spectrum such that: the mean transmission in the wavelength range between 380 nm inclusive and 780 nm inclusive is less than 60%; the mean transmission at wavelengths less than or equal to 400 nm is less than 1%, preferably less than 0.5%, very preferably less than 0.1%; the mean transmission at wavelengths greater than 400 nm inclusive and less than 500 nm inclusive is less than 30% with a transmission minimum ( 100 ) of less than 10%, preferably less than 5%, very preferably less than 1% between 425 nm and 445 nm inclusive.

ANTI-CANCER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

The invention relates to a compound of formula (I), more specifically in the levorotatory form (1a) thereof, in particular the form having a rotatory power [α]D=−38.6+0.7 at a concentration of 0.698 mg/ml in methanol. The compound may be in the form of a base or an acid addition salt, in particular a pharmaceutically acceptable acid. The compound is a selective Aurora A and B kinase inhibitor and can be used as an anticancer drug. 115-. (canceled)17. The method of claim 16 , wherein the compound is in levogyratory form.18. The method of claim 16 , wherein the compound exhibits an optical rotation [α]=−38.6±0.7 at a concentration of 0.698 mg/ml in methanol.19. The method of claim 16 , wherein the compound is in the form of a base or addition salt with an acid.20. The method of claim 19 , wherein the compound is a pharmaceutically acceptable acid. The present invention relates to the compound of formula (I):and to the pharmaceutical composition comprising it. This compound is preferably the levogyratory compound (Ia). This compound can be used as an anti-cancer ingredient. The invention also relates to a process for preparing the compound (I) or (Ia) and also to some of the intermediates in said process.A number of cancer treatment strategies are aimed at inhibiting the Aurora-type kinases, particularly Aurora A and B, which are involved in the regulation of mitosis; in this regard, see 2004, 4, 927-936. 2002, 94, 13202002, 21, 6175. 2009, 29(4), 1059-10712005, 15(9), 1169-1182. 2008, 14(6), 1639.Some Aurora inhibitor compounds (for example, MLN-8237 from Millennium, AZD-1152 from Astra-Zeneca or SNS-314 from Sunesis) are presently under evaluation in clinical trials. MLN-8237 is selective for Aurora A while AZD-1152 is selective for Aurora B. Since both kinases, Aurora A and B, are deregulated in cancer, inhibiting both Aurora A and B provides an advantage relative to selective inhibition of one kinase or the other. Moreover, multikinase compounds are in existence, ...

Method and device for monitoring a critical path of an integrated circuit

A device for monitoring a critical path of an integrated circuit includes a replica of the critical path formed by sequential elements mutually separated by delay circuits that are programmable though a corresponding main multiplexer. A control circuit controls delay selections made by each main multiplexer. A sequencing module operates to sequence each sequential element using a main clock signal by delivering, in response to a main clock signal, respectively to the sequential elements, secondary clock signals that are mutually time shifted in such a manner as to take into account the propagation time inherent to the main multiplexer.

METHODS AND SYSTEM FOR OIL IMMERSION COOLING

A system for immersion cooling computing system equipment includes a container containing a volume of immersion cooling fluid. At least one heat generating computing system equipment component and a liquid-liquid heat exchanger are disposed in the volume of immersion cooling fluid. A manifold system is disposed between the heat generating computing system equipment component and the liquid-liquid heat exchanger to direct a flow of immersion cooling fluid between the heat generating computing system component and the liquid-liquid heat exchanger and to isolate the flow of immersion cooling fluid from a bulk amount of immersion cooling fluid. The flow of immersion cooling fluid and the bulk amount of immersion cooling fluid constitutes the volume of immersion cooling fluid. 1. A system for immersion cooling computing system equipment , the system comprising:a container;a volume of immersion cooling fluid disposed in the container;at least one heat generating computing system equipment component disposed in the volume of immersion cooling fluid;a liquid-liquid heat exchanger disposed in the volume of immersion cooling fluid; anda manifold system disposed between the at least one heat generating computing system equipment component and the liquid-liquid heat exchanger to direct a flow of immersion cooling fluid between the at least one heat generating computing system component and the liquid-liquid heat exchanger and to isolate the flow of immersion cooling fluid from a bulk amount of immersion cooling fluid, the flow of immersion cooling fluid and the bulk amount of immersion cooling fluid comprising the volume of immersion cooling fluid.2. The system of claim 1 , wherein the container comprises a plastic tank.3. The system of claim 2 , wherein the plastic tank comprises high density polyethylene.4. The system of claim 1 , wherein the immersion cooling fluid comprises dielectric oil.5. The system of claim 1 , wherein the at least one heat generating computing system ...

Actuation of a hand intended for being provided on a humanoid robot

A hand intended for a humanoid robot comprises a palm and several fingers that are motorized relative to the palm. According to the invention, the hand comprises an actuator common to several fingers and a spreader making it possible to distribute a force exerted by the actuator toward the fingers.

Tire Including A Set Of One Or More Knitted Fabrics

The tire () comprises at least one set () of at least two layers of at least one knit (), the two layers being at least partially superposed on one another. The knit () comprises: columns of loops arranged one after the other substantially in an overall direction (X) referred to as the main direction, rows of loops arranged one beside the other substantially in an overall direction (Z) referred to as the transverse direction. The knit () has a force at 100% elongation less than or equal to 40 N·rowand/or 40 N·column, the force at 100% elongation being determined from a force-elongation curve obtained by applying standard ISO 13934-1:2013 to the or each knit () embedded in the standard elastomer matrix and the number of rows and/or columns being measured in accordance with standard NF EN 14971. 1. A tire comprises at least one set of at least two layers of at least one knit , the two layers being at least partially superposed on one another , the or each knit comprising:columns of loops, the loops of one and the same column being arranged one after the other substantially in an overall direction referred to as the main direction;rows of loops, the loops of one and the same row being arranged one beside the other substantially in an overall direction referred to as the transverse direction;{'sup': −1', '−1, 'the or each knit having a force at 100% elongation less than or equal to 40 N·rowand/or 40 N·column, the force at 100% elongation being determined from a force-elongation curve obtained by applying standard ISO 13934-1:2013 to the or each knit embedded in the standard elastomer matrix and the number of rows and/or columns being measured in accordance with standard NF EN 14971.'}2. The tire according to the claim 1 , wherein the or each knit having a force at 100% elongation less than or equal to 35 N·rowand/or 35 N·column claim 1 , the force at 100% elongation being determined from a force-elongation curve obtained by applying standard ISO 13934-1:2013 to the or ...

TEXTILE CORD HAVING AN AT LEAST TRIPLE TWIST

A textile cord () with at least triple twist (T, T, T) comprises at least N strands (), N being greater than 1, twisted together with a final twist T and a final direction D, each strand being made up of M pre-strands (), M being greater than 1, themselves twisted together with an intermediate twist T (T, T, T, T) and an intermediate direction D opposite to D, each pre-strand itself consisting of a yarn () which has been twisted on itself beforehand with an initial twist T (T, T, T) and the direction D, in which at least half of the N times M yarns have an initial elastic modulus denoted Mi which is greater than 800 cN/tex. This textile cord can advantageously be used as a reinforcer in tires for vehicles, particularly in the belt or carcass reinforcement of these tires. 122.-. (canceled)23. A textile cord with at least triple twist comprising:{'b': 3', '2, 'at least N strands, N being greater than 1, twisted together with a twist T and a direction D,'}{'b': 2', '1', '2, 'wherein each strand is made up of M pre-strands, M being greater than 1, themselves twisted together with a twist T and a direction D opposite to D,'}{'b': 1', '1, 'wherein each pre-strand consists of a yarn which has been twisted on itself with a twist T and the direction D, and'}wherein at least half of the N times M yarns have an initial elastic modulus denoted Mi which is greater than 800 cN/tex.24. The textile cord according to claim 23 , wherein N varies in a range from 2 to 6.25. The textile cord according to claim 24 , wherein N varies in a range from 2 to 4.26. The textile cord according to claim 23 , wherein M varies in a range from 2 to 6.27. The textile cord according to claim 26 , wherein M varies in a range from 2 to 4.28. The textile cord according to claim 23 , wherein the total number N times M of yarns is comprised in a range from 4 to 25.29. The textile cord according to claim 28 , wherein the total number N times M of yarns is comprised in a range from 4 to 16.301. The textile ...

Aramid textile cord with an at least triple twist

An aramid textile cord ( 50 ) with at least triple twist (T 1 , T 2 , T 3 ) comprises at least N strands ( 20 a, 20 b, 20 c, 20 d ), N being greater than 1, twisted together with a final twist T 3 and a final direction D 2 , each strand being made up of M pre-strands ( 10 a, 10 b, 10 c ), M being greater than 1, themselves twisted together with an intermediate twist T 2 (T 2 a , T 2 b , T 2 c , T 2 d ) and an intermediate direction D 1 opposite to D 2 , each pre-strand itself consisting of a yarn ( 5 ) which has been twisted on itself beforehand with an initial twist T 1 (T 1 a , T 1 b , T 1 c ) and the direction D 1 , in which at least half of the N times M yarns are aramid yarns. This textile cord can advantageously be used as a reinforcer in tires for vehicles, particularly in the belt or carcass reinforcement of these tires.

HIGH MODULUS TEXTILE CORD WITH AN AT LEAST TRIPLE TWIST

A high modulus textile cord () with at least triple twist (T1, T2, T3) comprises at least N strands (), N being greater than 1, twisted together with a final twist T3 and a final direction D2, each strand being made up of M pre-strands (), M being greater than 1, themselves twisted together with an intermediate twist T2 (T2a, T2b, T2c, T2d) and an intermediate direction D1 opposite to D2, each pre-strand itself consisting of a yarn () which has been twisted on itself beforehand with an initial twist T1 (T1a, T1b, T1c) and the direction D1, in which at least half of the N times M yarns have an initial elastic modulus denoted Mi which is greater than 2000 cN/tex. This textile cord can advantageously be used as a reinforcer in tires for vehicles, particularly in the belt or carcass reinforcement of these tires. 121.-. (canceled)22. A textile cord with at least triple twist comprising:at least N strands, N being greater than 1, twisted together with a twist T3 and a direction D2,wherein each strand is made up of M pre-strands, M being greater than 1, themselves twisted together with a twist T2 and a direction D1 opposite to D2,wherein each pre-strand consists of a yarn which has been twisted on itself with a twist T1 and the direction D1, andwherein at least half of the N times M yarns have an initial elastic modulus denoted Mi which is greater than 2000 cN/tex.23. The textile cord according to claim 22 , wherein N varies in a range from 2 to 6.24. The textile cord according to claim 23 , wherein N varies in a range from 2 to 4.25. The textile cord according to claim 22 , wherein M varies in a range from 2 to 6.26. The textile cord according to claim 25 , wherein M varies in a range from 2 to 4.27. The textile cord according to claim 22 , wherein the total number N times M of yarns is comprised in a range from 4 to 25.28. The textile cord according to claim 27 , wherein the total number N times M of yarns is comprised in a range from 4 to 16.29. The textile cord ...

Method for managing the operation of a circuit with triple modular redundancy and associated device

A method for managing operation of a logic component is provided, with the logic component including a majority vote circuit and an odd number of flip-flops equal to at least three. The method includes, following a normal operating mode of the logic component, placing a flip-flop in a test mode, and injecting a test signal into a test input of the flip-flop being tested while a logic state of the other flip-flops is frozen. A test signal output is analyzed. At the end of the test, the logic component is placed back in the normal operating mode. The majority vote circuit restores a value of the output signal from the logic component that existed prior to initiation of the test.

Stent for repair of anastomasis surgery leaks

A stent for repairing post-anastomasis (e.g., bariatric) surgery leaks is formed by an elongated tube having a proximal flare-shaped flange, an enlarged middle section, and a distal flare-shaped flange, where an exterior surface of the elongated tube is substantially covered with a polymer.

Moving object with combined movement

A mobile that can move on a horizontal plane, including a body comprising a contact area in contact with the horizontal plane, a cam movable in rotation relative to the body about a cam axis, the cam having a contact surface in contact with the horizontal plane during its rotation. According to the invention, the contact surface of the cam comprises separate first and second portions, each of the first and second portions having a different coefficient of friction, the coefficient of friction of the first portion being greater than the coefficient of friction of the second portion, the first portion being configured to roll without slipping on the horizontal plane, the second portion being configured to slip without rolling on the horizontal plane, and in that the body is configured to rotate relative to the horizontal plane about a vertical axis perpendicular to the cam axis when the first portion rolls without slipping on the horizontal plane and to rotate relative to the horizontal plane about a horizontal axis perpendicular to the cam axis and to the vertical axis when the second portion slips without rolling on the horizontal plane.

NOVEL CRYPTOPHYCIN COMPOUNDS AND CONJUGATES, THEIR PREPARATION AND THEIR THERAPEUTIC USE

The present invention relates to cryptophycin compounds of formula (I). The invention also relates to cryptophycin payloads, to cryptophycin conjugates, to compositions containing them and to their therapeutic use, especially as anticancer agents. The invention also relates to the process for preparing these conjugates. 3. The Cryptophycin compound of formula (I) according to claim 1 , wherein Rrepresents a methyl group.4. The Cryptophycin compound of formula (I) according to claim 1 , wherein:{'sub': 2', '3, 'each of Rand Rrepresents a hydrogen atom, or'}{'sub': 2', '3', '2', '3, 'one of Rand Rrepresents a methyl group and the other one represents a hydrogen atom, or Rand Rform together with the carbon atom to which they are attached a cyclopropyl group.'}5. (canceled)6. (canceled)7. The Cryptophycin compound of formula (I) according to claim 1 , wherein each of Rand Rrepresents a methyl group.8. The Cryptophycin compound of formula (I) according to claim 1 , wherein Rrepresents a hydrogen atom.9. The Cryptophycin compound of formula (I) according to claim 1 , wherein Rand Rrepresent independently of each other claim 1 , a hydrogen atom or a (C-C)alkyl group.10. The Cryptophycin compound of formula (I) according to claim 1 , wherein Rrepresents two substituents selected from a methoxy group and a chlorine atom.11. The Cryptophycin compound of formula (I) according to claim 1 , wherein Rrepresents a hydrogen atom.12. The Cryptophycin compound of formula (I) according to claim 1 , wherein:{'sub': 1', '1', '6, 'Rrepresents a (C-C)alkyl;'}{'sub': 2', '3, 'each of Rand Rrepresents a hydrogen atom;'}{'sub': '6', 'Rrepresents a hydrogen atom;'}{'sub': '9', 'Rrepresents two substituents selected from a methoxy group and a chlorine atom; and'}{'sub': '10', 'Rrepresents a hydrogen atom.'}13. The Cryptophycin compound of formula (I) according to claim 1 , wherein:{'sub': 1', '1', '6, 'Rrepresents a (C-C)alkyl;'}{'sub': 2', '3', '1', '6, 'Rand Rrepresents a (C-C)alkyl, and the ...

Substituted benzimidazole compounds and their use for the treatment of cancer

New benzimidazole compounds of formula I and their use as cyclin-dependent kinases inhibitors compounds as well as new pharmaceutical compositions containing them. (Formula I).

Rear projection fabric, rear projection screen and rear projection system

Die Erfindung hat - ausgehend von der Erkenntnis, dass sich dünne Gewebe mit hoher Fadendichte in hohem Maße dazu eignen, detailgenaue Rückprojektionen bei größter Weitwinkligkeit zu erlauben - in erfindungsgemäßer Weise ein Rückprojektionsgewebe (20, 30) angegeben mit einer Anzahl von Fäden (21, 23, 31, 33) bei einer Fadendichte von mehr als sieben Fäden pro Millimeter und einem größten Durchmesser eines Fadens von weniger als 0,06 mm. Die Erfindung führt auf eine Rückprojektionsbildwand (10), aufweisend ein solches Rückprojektionsgewebe (20, 30), die in der Lage ist, ein besonders detailgenaues Rückprojektionsbild (41) bei hoher Weitwinkligkeit zur Verfügung zu stellen. Insbesondere ist es möglich, mit einer solchen Rückprojektionsbildwand (10) ein vergleichsweise preiswertes Rückprojektionssystem (40) anzugeben, das mit üblichen Leistungen eines Projektors (43), beispielsweise in Form eines Beamers oder Lasers, ausgeführt werden kann. The invention has - starting from the knowledge that thin fabrics with high thread density are highly suitable for detailed backprojections at maximum Weitwinkligkeit to allow - in accordance with the invention a rear projection fabric (20, 30) indicated with a number of threads (21, 23 , 31, 33) at a thread density of more than seven threads per millimeter and a maximum diameter of a thread less than 0.06 mm. The invention leads to a rear projection screen (10) comprising such a rear projection fabric (20, 30) capable of providing a highly detailed rear projection image (41) at high angularity. In particular, it is possible with such a rear projection screen (10) to specify a comparatively inexpensive rear projection system (40) which can be designed with conventional powers of a projector (43), for example in the form of a beamer or laser.

METHODS AND SYSTEMS FOR FLUID IMMERSION COOLING

A system for immersion cooling electronic components includes a cylindrical container having a circular cross section, a cooling element disposed in the cylindrical container and containing a first cooling fluid, and a volume of a second cooling fluid disposed in the cylindrical container and in contact with the cooling element for exchange of heat between the second cooling fluid and the first cooling fluid, the second cooling fluid comprising an immersion cooling fluid. A heat generating electronic component is disposed within the cylindrical container and at least partially immersed in the second cooling fluid for exchange of heat between the electronic component and the second cooling fluid, and a fluid circulating device is disposed in the second cooling fluid to direct a flow of the second cooling fluid through the electronic component and over the cooling element.

Continuous flow micro device in which local temperature cycles act on a flowing sample

Provided is a microfluidic device comprising a microfluidic substrate comprising at least one pathway for sample flow; and at least one thermal transfer member which is capable of cycling between at least two temperatures. The thermal transfer member is adapted to heat at least a portion of the sample pathway while a sample is flowing along said at least a portion of said sample pathway. Provided also are methods of carrying out biochemical protocols using such a device.

Nematic liquid-crystal cell weakly doped by a chiral solution, it being of the electrically-controlled birefringence type

Ferroelectric liquid crystal display device

Ferroelectric liquid crystal display device. This device comprises a first display cell 30a, interposed between a first and a second crossed polariser 32, 34 enclosing a first ferroelectric smectic liquid crystal 42a interposed between a first electrode 44a and a first backing electrode 46a of appropriate shape for the display; a second display cell 30b, arranged between the second polariser 34 and the first display cell 30a, enclosing a second ferroelectric smectic liquid crystal 42b interposed between a second electrode 44b and a second backing electrode 46b and means 50a, 50b for delivering to the electrodes and backing electrodes alternating electrical signals serving to control an electrooptical property of the first and second liquid crystals.

Method of producing a phase device based on a twisted liquid crystal having optimized structure operating under unpolarized light

The invention relates to a method of producing a phase device operating at at least one wavelength (λ) comprising a cell containing a liquid crystal possessing a helical structure, inserted between two alignment layers possessing rubbing axes and means for applying a voltage to said cell, said helical structure exhibits a number of helical turns k, said liquid crystal exhibiting a defined angle of twist Θ between the rubbing axes of the two alignment layers, characterized in that it comprises the following steps: - the determination of a compensation angle ε satisfying the following equation: (formula) with: N the integer closest to (formula) the angle of twist Θ=2Kπ-ε Δn: the birefringence of the liquid crystal; d: the thickness of the liquid crystal cell; λ : the wavelength of the light beam which passes through the liquid crystal cell; the rubbing of one of the faces in a direction of alignment of said liquid crystal molecules, defining the angle of twist: θ = 2Kπ-ε.

Radiopaque marker system and method of use

A temporary and retrievable radiopaque marker and discrete radiopaque marker for use on an implantable endoprosthesis. The elongate marker has a proximal end, a distal end, and a thickness. At least a portion of the marker is radiopaque and the marker is removably-attached to the implantable endoprosthesis.

Stent and stent-graft for treating branched vessels

An implantable stent and stent-graft for treating a patient having a relatively healthy first aorta portion upstream from a renal artery branch, and a diseased aorta portion downstream from the renal artery branch. One embodiment of the device includes a fixation section, a renal artery branch section and a diseased aorta section, all of which can be tubular, radially compressible and self-expandable structures formed from a plurality of filaments which are helically wound in a braided configuration. When the device is implanted and in its expanded state, the fixation section engages the first aorta portion upstream from a renal artery branch to provide substantial anchoring support. The diseased aorta section engages the portion of the aorta downstream from the renal artery branch and extends across the diseased portion of the aorta for purposes of treatment. The renal artery branch section extends across the renal artery branch and connects the diseased aorta section to the fixation section while allowing blood flow between the aorta and renal artery branch.

Radiopaque markers and methods of using the same

A temporary and retrievable radiopaque marker and discrete radiopaque marker for use on an implantable endoprosthesis. The elongate marker has a proximal end, a distal end, and a thickness. At least a portion of the marker is radiopaque and the marker is removably-attached to the implantable endoprosthesis.

Stent with anti-migration feature

An intraluminal prosthesis includes an outer three-dimensional (3D) anti-migration structure that is attached to the outer wall of a fully covered or partially covered stent to prevent migration and still allow stent removal at a later period of time. A method of manufacturing the intraluminal prosthesis includes attaching the anti-migration structure by usage of a polymer such as polyurethane.

Vision catheter having electromechanical navigation

Embodiments of the present invention are generally directed to a visualization system including a small gauge vision catheter that is designed to be standalone or received within an instrument channel of a larger endoscope. The vision catheter has imaging means disposable within an imaging channel, a working channel, and an electromagnetic sensor element insertable into the working channel of the catheter to provide position tracking. The working channel of the catheter also provides access for therapeutic and diagnostic tools.

Method for carrying out a biochemical protocol in continuous flow in a microreactor

Devices and methods for carrying out a chemical or biochemical protocol are disclosed. In one embodiment, the chemical or biochemical protocol is performed by cycling at least one thermal transfer member between at least two temperatures while liquid samples on which the chemical or biochemical protocol is to be performed are continuously moving through at least one temperature regulated zone upon which the at least one thermal transfer member acts. In some embodiments, the device comprises a sample transport member that comprises liquid samples in sample receiving regions. The sample transport member moves the samples continuously through a temperature regulated zone which cycles between at least two temperatures while the liquid samples are moving through a temperature regulated zone on which at least one thermal transfer member acts. In some embodiments, the sample receiving regions comprise wells, hydrophillic films or hydrophillic filaments.

Substituted benzimidazole compounds and their use for the treatment of cancer

New benzimidazole compounds of formula I and their use as cyclin-dependent kinases inhibitors compounds as well as new pharmaceutical compositions containing them. (Formula I).

Substituted imidazole compounds and their use in the treatment of cancer

Substituted benzimidazole compounds and their use for the treatment of cancer

New benzimidazole compounds of formula I and their use as cyclin-dependent kinases inhibitors compounds as well as new pharmaceutical compositions containing them. (Formula I).

Substituted benzimidazole compounds and their use for the treatment of cancer

Substituted benzimidazole compounds and their use for the treatment of cancer

Substituted benzimidazole compounds and their use for the treatment of cancer

SUBSTITUTED BENZIMIDAZOLE AND ITS APPLICATION IN CANCER TREATMENT

Substituted benzimidazole compounds and their use for the treatment of cancer

New benzimidazole compounds of formula I and their use as cyclin-dependent kinases inhibitors compounds as well as new pharmaceutical compositions containing them. (Formula I).

Substituted benzimidazole compounds and their use for the treatment of cancer

Disclosed are compounds of formula (I), wherein: A is phenyl, R1 is optionally substituted, alkoxy, aryl or heteroaryl, halogen, 4NH2, 4NH alkyl or cycloalkyl optionally substituted with an acyl, an acylderivative, hydroxy, an amino, alkoxy, heterocyclyl or aryl; 4N imidazolyl, or 3SO2Me, R2 is optionally substituted CO-alkyl, CO-aralkyl, CO-aryl, CO-alkoxy, CO-amino, CO-NHR3, CO-NR3R4, aryl or aralkyl. The compounds are used for the preparation of medicaments for use in treating cancer diseases.

Substituted benzimidazole compounds and their use in the manufacture of drugs for the treatment of cancer

Substituted benzimidazole compounds and their use for the treatment of cancer

The present invention discloses and claims benzimidazole compounds of formula (I): in which A is aryl or heteroaryl; R 1 is selected from optionally substituted alkyl, alkoxy, aryl or heteroaryl, NH-lower alkyl or NH-cycloalkyl, or halogen, NH 2 ; 1-imidazolyl or SO 2 Me; R 2 is selected from optionally substituted —CO-alkyl, —CO-cycloalkyl, —CO-aralkyl, —CO-aryl, —CO-alkoxy, aryl or aralkyl, or —CO-amino, CO—NHR 3 or CO—R 3 R 4 wherein R 3 and R 4 are selecteded independently from hydrogen, alkyl, hydroxyalkyl, alkoxyalkyl, fluoroalkyl, alkynyl, heteroalkyl, alkylheteroalkyl, aryl, aralkyl or together form an alkylene chain optionally containing one to 4 heteroatoms; a pharmaceutically acceptable salt or a prodrug thereof; the use of compounds of formula (I) for the treatment of cancer, and pharmaceutical compositions comprising a compound of formula (I) and one or more pharmaceutically acceptable adjuvants or diluents.

Substituted benzimidazole compounds and their use for the treatment of cancer

Substituted benzimidazole compounds and their use for the treatment of cancer

New benzimidazole compounds of formula (I) and their use as cyclin-dependent kinases inhibitors compounds as well as new pharmaceutical compositions containing them.

Substituted benzimidazole compounds and their use for cancer therapy

Νέες ενώσεις βενζιμιδαζόλης του τύπου I και η χρήση τους ως ενώσεις αναστολέων κινάσης που εξαρτώνται από την κυκλίνη καθώς και νέες φαρμακευτικές ενώσεις που τις περιέχουν. (Τύπος I). New benzimidazole compounds of formula I and their use as cyclin-dependent kinase inhibitors as well as novel pharmaceutical compounds containing them. (Type I).

SUBSTITUTED BENCIMIDAZOL COMPOUNDS AND THEIR USE FOR THE TREATMENT OF CANCER.

Compuestos de fórmula (I) (Ver fórmula) * en la que A es fenilo * en la que R1 se selecciona entre uno o más grupos similares seleccionados entre: - alquilo, eventualmente sustituido con un alcoxi, heteroalquilo, arilo, acilo, derivados de acilo, halógeno -alcoxi eventualmente sustituido con un alquilo, heteroalquilo, arilo, heteroarilo, alcoxialquilo, hidroxialquilamida o un grupo perfluoroalcoxi o un alquiltio eventualmente sustituido con un amida o un perfluoroalquiltio -arilo o heteroarilo eventualmente sustituido con uno o más de un grupo alquilo, un grupo alcoxi, un grupo nitro, un grupo ciano, acil alquil éster, carbamoil éster, un grupo perfluoroalcoxi, un grupo perfluoroalquilo, un grupo heteroarilo, un grupo ariloxi -halógeno -4 NH2 -4 NH alquilo o cicloalquilo eventualmente sustituido con un acilo, un derivado de acilo, un hidroxi, un amino, alcoxi, heterociclilo o un grupo arilo -4 N imidazolilo -3 SO2Me en la que R2 se selecciona entre el grupo que consiste en -CO-alquilo eventualmente sustituido con amino, un ácido, un derivado de ácido, alcoxi, arilo o grupos OH -CO-aralquilo eventualmente sustituido con alcoxi, halógeno, amino, ácido o derivados de ácido -CO-arilo eventualmente sustituido -CO-alcoxi eventualmente sustituido con arilo; -CO-amino, CO-NHR3, CO-NR3R4, donde R3 y R4 se seleccionan independientemente entre hidrógeno, alquilo, hidroxialquilo, alcoxialquilo, fluoroalquilo, alquinilo, heteroalquilo, alquilheteroalquilo, arilo, aralquilo o juntos forman una cadena alquileno que incluye eventualmente de uno a 4 heteroátomos -arilo o aralquilo eventualmente sustituido con heterocicloalquilo, alquilo, arilo, alcoxi, amino, fluroroalquilo, derivados de acilo, halógeno o una sal farmacéuticamente aceptable con la condición de que R1 no pueda ser halógeno, alquilo (C2-C4), cicloalquilo (C3-C8), CF3 o alcoxi (C1-C4) donde R2 es -CO-alcoxi donde en los sustituyentes anteriores, alquilo contiene de 1 a 10 átomos de carbono, alcoxi de 1 a 4 átomos de ...

SUBSTITUTED BENZIMIDAZOL COMPOUNDS AND ITS USE IN CANCER TREATMENT

LA PRESENTE INVENCION SE REFIERE A COMPUESTOS CUYA FORMULA GENERAL APARECE EN EL PRESENTE RESUMEN Y DONDE R1,R2,A, SON GRUPOS FUNCIONALES DESCRITOS EN EL EXPEDIENTE. ESTOS COMPUESTOS TIENEN COMO OBJETIVO PRINCIPAL EL DE INHIBIR LAS QUINASAS DEPENDIENTES DE LA CICLINA (CDK) PARA BLOQUEAR LA PROGRESION DEL CICLO CELULAR Y EL CRECIMIENTO DE CELULAS TUMORALES POR LO QUE SON DE UTILIDAD EN CUADROS NEOPLASICOS CARACTERIZADOS POR LA PROLIFERACION DE CELULAS QUE NO SE ENCUENTRAN SUJETAS A CONTROLES DE PROLIFERACION CELULAR NORMAL.

Substituted benzimidazole compounds and their use for the treatment of cancer

THE PRESENT INVENTION DISCLOSES AND CLAIMS BENZIMIDAZOLE COMPOUNDS OF FORMULA (I): IN WHICH A IS ARYL OR HETEOARYL;R1 IS SELECTED FROM OPTIONALLY SUBSTITUED ALKYL,ALKOXY,ARYL OR HETEROARYL,NH-LOWER ALKYL OR NH-CYCLOALKYL,OR HALOGEN,NH2;1-IMIDAZOLYL OR SO2ME; R2 IS SELECTED FROM OPTIONALLY SUBSTITTUED –CO-ALKYL,-CO-CYCLOALKYL,-CO-ARALKYL,-CO-ARYL,-CO-ALKOXY,ARYL OR ARALKYL,OR –CO-AMINO,CO-NHR3 OR CO-R3R4 WHEREIN R3 AND R4 ARE SELECTED INDEPENDENTLY FROM HYDROGEN, ALKYL, HYDROXYALKYL, ALKOXYALKYL, FLUOROALKYL, ALKYNYL, HETEROALKYL, ALKYLHETEROALKYL,ARYL,ARALKYL OR TOGETHER FORM AN ALKYLENE CHAIN OPTIONALLY CONTAINING ONE TO 4 HETEROATOMS;A PHARMACEUTICALLY ACCEPTABLE SALT OR A PRODRUG THEREOF;THE USE COMPOUNDS OF FORMULA (I) FOR THE TREATMENT OF CANCER,AND PHAMACEUTICAL COMPOSITIONS COMPRISING A COMPOUND OF FORMULA (I) AND ONE OR MORE PHARMACEUTICALLY ACCEPTABLE ADJUVANTS OR DILUENTS.

SUBSTITUTED BENZIMIDAZOL COMPOUNDS AND THEIR USE FOR CANCER TREATMENT

LOS NUEVOS COMPUESTOS DE BENCIMIDAZOL Y SU USO COMO COMPUESTOS DE INHIBIDORES DE CINASAS DEPENDIENTES DE CICLINA ASI COMO TAMBIEN NUEVAS COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN THE NEW BENCIMIDAZOL COMPOUNDS AND THEIR USE AS COMPOUNDS OF CYCLINE DEPENDENT KINNER INHIBITORS AS WELL AS ALSO NEW PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

SUBSTITUTE BENZIMIDAZOLE COMPOUNDS

SE REFIERE A DERIVADOS DE SULFONOESTERES DE CARBAMATOS DE FORMULA I DONDE ANILLO A ES ARILO, HETEROARILO; R1 ES ALQUILO, ALCOXI, ARILO, HETEROARILO, HALOGENO, NH2, IMIDAZOLIL, NH-ALQUILO; R2 ES CO-ALQUILO, CO-ARALQUILO, CO-ARILO, CO-ALCOXI, CO-AMINO, CONHR3, CONR3R4, ARILO; R3 Y R4 SON H, ALQUILO, HIDROXIALQUILO, ALCOXIALQUILO, FLUOROALQUILO, ENTRE OTROS. SON COMPUESTOS PREFERIDOS METIL-5-(4-[2-HIDROXIETIL]AMINOFENILSULFONILOXI)BENCIMIDAZOL-2-CARBAMATO, METIL-5-(4-METILAMINOFENILSUFONILOXI)BENCIMIDAZOL-2-CARBAMATO, METIL-5-(4-[2-SULFONILETIL]AMINOFENILSULFONILOXI)BENCIMIDAZOL-2-CARBAMATO, ENTRE OTROS, LOS COMPUESTOS PUEDEN SER UTILES PARA INHIBIR LA PROLIFERACIN CELULAR REFERS TO CARBAMATE SULPHONESTERS DERIVATIVES OF FORMULA I WHERE RING A IS ARYL, HETEROARYL; R1 IS ALKYL, ALCOXY, ARYL, HETEROARYL, HALOGEN, NH2, IMIDAZOLIL, NH-ALKYL; R2 IS CO-ALKYL, CO-ARALKYL, CO-ARYL, CO-ALCOXY, CO-AMINO, CONHR3, CONR3R4, ARYL; R3 AND R4 ARE H, ALKYL, HYDROXYALKYL, ALCOXYALKYL, FLUOROALKYL, AMONG OTHERS. PREFERRED COMPOUNDS ARE METHYL-5- (4- [2-HYDROXYETHYL] AMINOPHENYLSULFONYLOXY) BENZYMIDAZOL-2-CARBAMATE, METHYL-5- (4-METHYLAMINOPHENYLSUFONYLOXY) BENZYMIDAZOL-2-CARBAMATE, [METHYL-2-CARBAMATE] AMINOPHENYLSULFONYLOXY) BENZIMIDAZOLE-2-CARBAMATE, AMONG OTHERS, THE COMPOUNDS MAY BE USEFUL TO INHIBIT CELL PROLIFERATION

Substituted benzimidazole compounds and their use for the treatment of cancer

Substituted benzimidazole compounds and their use for the treatment of cancer

Substituted benzimidazole compounds and their use for the treatment of cancer

SUBSTITUTED BENZIMIDAZOL COMPOUNDS AND THEIR USE FOR CANCER TREATMENT

Nuevos compuestos de benzimidazol y su uso como inhibidores de las cinasas dependientes de la ciclina, y nuevas composiciones farmacológicas que contienen los mismos. New benzimidazole compounds and their use as inhibitors of cyclin dependent kinases, and new pharmacological compositions containing them.

Substituted benzimidazole compounds and their use for the treatment of cancer.

New benzenesulfonates, useful to treat e.g. proliferation disorders such as cancers, are kinase inhibitors

Benzenesulfonates (I) are new. Benzenesulfonates of formula (I) and their isomers, enantiomers, diastereoisomers and mineral/organic acid/base addition salts are new. A = NH or S; R 1, R 2 = halo or optionally halo substituted T, preferably = Cl, F or CH 3; R 3 = H or as R 1, preferably H, CH 3 or CF 3; R = NR 4R 5; R 4, R 5 = H or T (optionally substituted by OH, T1 or NR 6R 7); R 6, R 7 = H or T; or NR 4R 5 or NR 6R 7 = cyclic radical (optionally containing heteroatoms such as O, S, N or NH (optionally substituted)); T = 1-6C alkyl; and T1 = 1-6C alkoxy. An independent claim is included for preparation of (I). [Image] ACTIVITY : Vasotropic; Antiinflammatory; Antiallergic; Antiasthmatic; Anticoagulant; Thrombolytic; Neuroprotective; Ophthalmological; Antipsoriatic; Antiarthritic; Antirheumatic; Antidiabetic; Muscular-Gen.; Cytostatic. MECHANISM OF ACTION : Kinase inhibitor; Met inhibitor. Tests details are described but no results given.

Benzimidazole and benzothiazole derivatives, method for preparing same, use thereof as drugs, pharmaceutical compositions and novel use especially as c-MET inhibitors

This invention relates to benzimidazole and benzothiazole compounds of formula (I) to methods of preparing such compounds, pharmaceutical compositions comprising such compounds, and to methods of treatment comprising administering of such compounds.

Novel benzimidazole and benzothiazole derivatives, method for preparing same, use thereof as drugs, pharmaceutical compositions and novel use in particular as c-met inhibitors

The invention concerns novel products of formula (I), wherein: A represents NH or S; R1, R2 and R3 represent H, NH2, Hal or Alk, one at least of R1, R2 and R3 being other than hydrogen; R represents in particular: cycloalkyl, alkyl, alkoxy or NR4R5, R4 representing H or Alk and R5 representing cycloalkyl or alkyl optionally substituted by hydroxyl, alkoxy, heteroaryl, heterocycloalkyl, NR6R7, phenyl, phenyl-NR6R7 and CONR6R7, R6 and R7 representing H or Alk or phenyl and R6 and R7 may form together with H a cyclic radical; R4 and R5 may also form together with N a cyclic radical; all the above heterocycloalkyl, heteroaryl and phenyl radicals being optionally substituted, said products being in all the isomeric forms and their salts, as medicines in particular as Met inhibitors.

Novel benzimidazole and benzothiazole derivatives, method for preparing same, use thereof as drugs, pharmaceutical compositions and novel use in particular as C-Met inhibitors

The invention concerns novel products of formula (I), wherein: A represents NH or S; R1, R2 and R3 represent H, NH2, Hal or Alk, one at least of R1, R2 and R3 being other than hydrogen; R represents in particular: cycloalkyl, alkyl, alkoxy or NR4R5, R4 representing H or Alk and R5 representing cycloalkyl or alkyl optionally substituted by hydroxyl, alkoxy, heteroaryl, heterocycloalkyl, NR6R7, phenyl, phenyl-NR6R7 and CONR6R7, R6 and R7 representing H or Alk or phenyl and R6 and R7 may form together with H a cyclic radical; R4 and R5 may also form together with N a cyclic radical; all the above heterocycloalkyl, heteroaryl and phenyl radicals being optionally substituted, said products being in all the isomeric forms and their salts, as medicines in particular as Met inhibitors.

Substituted benzimidazole compounds and their use for the treatment of cancer

New benzimidazole compounds of formula I and their use as cyclin-dependent kinases inhibitors compounds as well as new pharmaceutical compositions containing them. (Formula I).

Substituted benzimidazole compounds and their use for the treatment of cancer

SUBSTITUTED BENZIMIDAZOLE AND ITS APPLICATION IN CANCER TREATMENT

Substituted benzimidazole compounds and their use for the treatment of cancer

The present invention discloses and claims benzimidazole compounds of formula (I): in which A is aryl or heteroaryl; R 1 is sleceted from optionally substituted alkyl, alkoxy, aryl or heteroaryl, NH-lower alkyl or NH-cycloalkyl, or halogen, NH 2 ; 1-imidazolyl or SO 2 Me; R 2 is selected from optionally substituted —CO-alkyl, —CO-cycloalkyl, —CO-aralkyl, —CO-aryl, —CO-alkoxy, aryl or aralkyl, or —O-amino, CO—NHR 3 or CO—R 3 R 4 wherein R 3 and R 4 are selecteded independently from hydrogen, alkyl, hydroxyalkyl, alkoxyalkyl, fluoroalkyl, alkynyl, heteroalkyl, alkylheteroalkyl, aryl, aralkyl or together form an alkylene chain optionally containing one to 4 heteroatoms; a pharmaceutically acceptable salt or a prodrug thereof; the use of compounds of formula (I) for the treatment of cancer, and pharmaceutical compositions comprising a compound of formula (I) and one or more pharmaceutically acceptable adjuvants or diluents.

Substituted benzimidazole compounds and their use in the treatment of cancer

Substituted benzimidazole compounds and their use for the treatment of cancer

New benzimidazole compounds of formula I and their use as cyclin-dependent kinases inhibitors compounds as well as new pharmaceutical compositions containing them. (Formula I).

Substituted benzimidazole compounds and their use for the treatment of cancer

Nova jedinjenja bezoimidazola formule (I) i njihova primena kao inhibitorna jedinjenja ciklin - zavisnih kinaza kao i novi farmaceutski preparati koji sadrže ova jedinjenja.[New benzimidazole compounds of formula I and their use as cyclin-dependent kinases inhibitors compounds as well as new pharmaceutical compositions containing them. (Formula I).

Medical device having a constricted region for occluding fluid flow in a body lumen

The present invention is an occlusion device adapted for implantation into a fluid flow-supporting body lumen. The occlusion device comprises a flexible support structure and a flexible fluid flow-occluding membrane that is positioned concentric with the flexible support structure. The support structure is formed from a plurality of interwoven filaments that form an axially flexible and radially compressible structure that, in its expanded state, engages the lumen. The membrane generally includes a constricted region and constriction means, such as a mechanical seal, for closing the membrane at one end. The membrane is formed from a plurality of filaments, and in one embodiment, the membrane filaments are tightly interbraided with the structure filaments to form the occlusion device. Alternatively, the membrane is separately fabricated of interwoven filaments, and is positioned either within the support structure or without the structure so as to surround the support structure.

Shape memory tubular stent with grooves

An implantable, radially distensible stent (10) includes a tubular structure having opposed open ends (14, 16). The wall (10) of the stent (12) is made from a shape memory polymeric material. Grooves (22) may be disposed within an outer surface (20) of stent wall (12) to improve flexibility and drainage of the stent (10).

Biodegradable implants having accelerated biodegradation properties in vivo

The present invention is directed to a biodegradable implant including a biodegradable polymer previously exposed to conditions of biodegradation such as chemical, thermal or radiation degradation. The present invention further includes the possibility of attaching axial runners to the implant. The present invention is further directed to a method of forming a biodegradable implant, such as a stent, by irradiation of the individual filaments or fibers, or irradiation of the formed implant.

Rear projection fabric, rear projection screen, and rear projection system

Thin high-density fabrics are particularly suitable for super wide-angle rear projections that are accurate in every detail. Based on said recognition, the invention relates to a rear projection fabric ( 20, 30 ) that comprises a number of threads ( 21, 23, 31, 33 ) and has a density of more than seven threads per millimeter, the maximum diameter of a thread being less than 0.06 mm. The invention further relates to a rear projection screen ( 10 ) which comprises such a rear projection fabric ( 20, 30 ) and can create a wide-angle rear projection image ( 41 ) that is particularly accurate in every detail. More particularly, such a rear projection screen ( 10 ) makes it possible to create a relatively inexpensive rear projection system ( 40 ) which can be designed by means of the standard power of a projector ( 43 ), e.g. in the form of a beamer or laser.

Rear projection fabric, rear projection screen, and rear projection system

Thin high-density fabrics are particularly suitable for super wide-angle rear projections that are accurate in every detail. Based on said recognition, the invention relates to a rear projection fabric (20, 30) that comprises a number of threads (21, 23, 31, 33) and has a density of more than seven threads per millimeter, the maximum diameter of a thread being less than 0.06 mm. The invention further relates to a rear projection screen (10) which comprises such a rear projection fabric (20, 30) and can create a wide-angle rear projection image (41) that is particularly accurate in every detail. More particularly, such a rear projection screen (10) makes it possible to create a relatively inexpensive rear projection system (40) which can be designed by means of the standard power of a projector (43), e.g. in the form of a beamer or laser.

Rear projection fabric, rear projection screen, and rear projection system

Die Erfindung hat - ausgehend von der Erkenntnis, dass sich dünne Gewebe mit hoher Fadendichte in hohem Masse dazu eignen detailgenaue Rückprojektionen bei grösster Weitwinkligkeit zu erlauben - in erfindungsgemässer Weise ein Rückprojektionsgewebe (20, 30) angegeben mit einer Anzahl von Fäden (21, 23, 31, 33) bei einer Fadendichte von mehr als sieben Fäden pro Millimeter und einem grössten Durchmesser eines Fadens von weniger als 0,06 mm. Die Erfindung führt auf eine Rückprojektionsbildwand (10) aufweisend ein solches Rückprojektionsgewebe (20, 30), die in der Lage ist, ein besonders detailgenaues Rückprojektionsbild (41) bei hoher Weitwinkeligkeit zur Verfügung zu stellen. Insbesondere ist es möglich, mit einer solchen Rückprojektionsbildwand (10) ein vergleichsweise preiswertes Rückprojektionssystem (40) anzugeben, das mit üblichen Leistungen eines Projektors (43), beispielsweise in Form eines Beamers oder Lasers, ausgeführt werden kann.

Rear projection fabric, rear projection screen, and rear projection system

Thin high-density fabrics are particularly suitable for super wide-angle rear projections that are accurate in every detail. Based on said recognition, the invention relates to a rear projection fabric (20, 30) that comprises a number of threads (21, 23, 31, 33) and has a density of more than seven threads per millimeter, the maximum diameter of a thread being less than 0.06 mm. The invention further relates to a rear projection screen (10) which comprises such a rear projection fabric (20, 30) and can create a wide-angle rear projection image (41) that is particularly accurate in every detail. More particularly, such a rear projection screen (10) makes it possible to create a relatively inexpensive rear projection system (40) which can be designed by means of the standard power of a projector (43), e.g. in the form of a beamer or laser.

Variable geometry catalytic converter

A system is provided for reducing detectable hydrocarbons in the exhaust gas of a diesel engine and for retarding the formation of sulfate including a housing having an inlet and an outlet, a first exhaust gas glow passage extending from the inlet to the outlet within the housing, a first catalyst bed positioned within the first flow passage, a second exhaust gas flow passage extending from the inlet to the outlet within the housing, and a second catalyst bed positioned within the second flow passage. Also provided is a valve for directing the flow of the exhaust gas through one of the first and second flow passages, and an electronic control for controlling the valve in response to engine load and exhaust gas temperature such that the exhaust gas is directed through the first flow passage and the first catalyst bed under low engine load and low exhaust gas temperature conditions and through the second flow passage and the second catalyst bed under high engine load and high exhaust gas temperature conditions.

Apparatus, system, and method for particulate filter regeneration

An apparatus, system, and method are disclosed for particulate filter regeneration. The apparatus includes a bypass exhaust channel configured to conduct exhaust gasses away from a main exhaust channel and reintroduce the exhaust gasses into the main exhaust channel upstream from a particulate filter, a burner, and a regeneration module configured to monitor exhaust gas variables and divert a portion of the exhaust gasses through the bypass exhaust channel in response to the exhaust gas variables. The system includes a vehicle having an internal combustion engine coupled to a transmission, and the apparatus. The method includes conducting exhaust gasses away from a main exhaust channel and reintroducing the exhaust gasses into the main exhaust channel, raising the temperature of the exhaust gasses, and monitoring exhaust gas variables and selectively diverting a portion of the exhaust gasses through a bypass exhaust channel in response to the exhaust gas variables.

NEMATIC LIQUID CRYSTAL CELL LOWLY DOPED BY A CHIRAL SOLUTE, AND OF THE ELECTRICALLY CONTROLLED BIREFRINGENCE TYPE

CELLULE A CRISTAL LIQUIDE NEMATIQUE FAIBLEMENT DOPE PAR UN SOLUTE CHIRAL, ET DU TYPE A BIREFRINGENCE CONTROLEE ELECTRIQUEMENT. LE DOPAGE EST TEL QUE LE PAS DE TORSION DU CRISTAL LIQUIDE DE TYPE CHOLESTERIQUE RESULTANT SOIT SUPERIEUR A ENVIRON DEUX FOIS L'EPAISSEUR DE LA COUCHE DE CRISTAL LIQUIDE 2 ET INFERIEUR A ENVIRON HUIT FOIS CETTE EPAISSEUR. DE PLUS, L'UN DES COTES DE LA CELLULE ETANT DESTINE A ETRE EXPOSE A UNE LUMIERE INCIDENTE, LA CELLULE COMPREND, AU MOINS DUDIT COTE, UN POLARISEUR 14 AVANTAGEUSEMENT RECTILIGNE. APPLICATION A LA REALISATION DE DISPOSITIFS D'AFFICHAGE D'IMAGES ANIMEES. NEMATIC LIQUID CRYSTAL CELL LOW DOPED BY A CHIRAL SOLUTE, AND OF THE ELECTRICALLY CONTROLLED BIREFRINGENCE TYPE. THE DOPING IS SUCH THAT THE TORSION STEP OF THE RESULTING CHOLESTER-TYPE LIQUID CRYSTAL IS ABOUT TWICE THE THICKNESS OF THE LIQUID CRYSTAL LAYER 2 AND LESS THAN ABOUT EIGHT TIMES THAT THICKNESS. IN ADDITION, ONE SIDE OF THE CELL IS INTENDED TO BE EXPOSED TO INCIDENTAL LIGHT, THE CELL INCLUDES, AT LEAST ON THE SAID SIDE, A POLARIZER 14 ADVANTAGEOUSLY STRAIGHT. APPLICATION TO THE REALIZATION OF ANIMATED IMAGE DISPLAY DEVICES.

BATTERY RECHARGING ASSEMBLY AND RECHARGING METHOD USING SUCH ASSEMBLY

L'invention concerne un ensemble de rechargement (100) comprenant un objet (20) comprenant une batterie et une fiche (10) destinée à recharger la batterie, la fiche (10) étant connectable à une source électrique. Selon l'invention, l'objet (20) comprend une embase (21) apte à réceptionner la fiche (10), comprenant un premier connecteur électrique (22), un premier connecteur magnétique (23) apte à positionner la fiche (10) par rapport à l'embase (21). La fiche (10) comprend une surface de contact (11) de forme complémentaire à une surface de l'embase (21), un deuxième connecteur électrique (12) disposé de façon à entrer en contact avec le premier connecteur électrique (22) pour permettre un contact électrique entre les premier et deuxième connecteurs électriques (22, 12) quand la surface de contact (11) est positionnée sur la surface de l'embase (21), un deuxième connecteur magnétique (13), positionné à proximité de la surface de contact (11), attirant le premier connecteur magnétique (23), de façon à permettre l'alignement des premier et deuxième connecteurs électriques (23, 13) et le maintien du contact électrique pendant le rechargement de la batterie. Un parmi le premier et le deuxième connecteurs électriques (22, 12) est un connecteur surfacique (24) et l'autre parmi le premier et le deuxième connecteurs électriques est un connecteur ponctuel (14) disposé de façon à se poser contre le connecteur surfacique (24), pour plusieurs orientations distinctes de la surface de contact (11) sur l'embase (21). A recharging assembly (100) includes an object (20) including a battery and a plug (10) for recharging the battery, the plug (10) being connectable to an electrical source. According to the invention, the object (20) comprises a base (21) adapted to receive the plug (10), comprising a first electrical connector (22), a first magnetic connector (23) adapted to position the plug (10) relative to the base (21). The plug (10) comprises ...