System and method for workflow processing using a portable knowledge format

The present invention relates to systems and methods for performing one or more steps of a work process using a work process data structure and a portable knowledge format. The method of the present invention comprises constructing a work process data structure that identifies one or more steps of a work process. The work process data structure is distributed. Content is retrieved from an accessible data structure that includes the content, metadata and an index as indicated by the one or more steps. The content is delivered to the one or more locations identified in the work process data structure.

Efavirenz tablet formulation having unique biopharmaceutical characteristics

The present invention provides an efavirenz tablet formulation which, when administered as a single dose to a subject, provides a mean maximum plasma concentration (Cmax) of about 4 μM to about 14 μM, a mean time of maximum plasma concentration (Tmax) of about 2 hours to about 5 hours, and a mean area under the plasma concentration versus time curve from time zero to time infinity (AUC) of about 190 μM hour to about 470 μM hour.

Substituted morpholine compounds for the treatment of central nervous system disorders

This invention relates to compounds of the formulae I wherein R1-R8, A, X, and Z are defined as in the specification, pharmaceutical compositions containing them and their use in the treatment of central nervous system disorders.

Authentication and pairing of devices using a machine readable code

An MR code is generated within a browser on a client device and is read by a mobile application on a mobile device. A communication channel is then established through a web-based service, between the browser and the mobile application on the mobile device. The mobile application generates a user interface display on the mobile device that allows user selection of content. The mobile application sends a link to that content to the browser, which accesses and renders the content on the client device. User input commands to control the rendered content are also received at the mobile device and sent to the browser through the communication channel.

AUTHENTICATION AND PAIRING OF DEVICES USING A MACHINE READABLE CODE

An MR code is generated within a browser on a client device and is read by a mobile application on a mobile device. A communication channel is then established through a web-based service, between the browser and the mobile application on the mobile device. The mobile application generates a user interface display on the mobile device that allows user selection of content. The mobile application sends a link to that content to the browser, which accesses and renders the content on the client device. User input commands to control the rendered content are also received at the mobile device and sent to the browser through the communication channel. 1. A computer-implemented method , comprising:receiving, at a mobile device, a machine readable code (MR code) from a a client device;obtaining, at the mobile device, a session identifier (session id) from the MR code;sending the session id to a remote system; andin response to sending the session id to the remote system, receiving a pairing input at the mobile device that pairs the mobile device for communication with the client device over a communication channel through the remote system.2. The computer-implemented method of wherein sending the session id to the remote system comprises:sending a user token authenticating a user, and the session id, to the remote system.3. The computer-implemented method of wherein receiving a pairing input comprises:receiving the pairing input to match the mobile device with a browser that has the user token for accessing content accessible to the user.4. The computer-implemented method of and further comprising:sending control outputs from the mobile device, based on control user inputs received at the mobile device, over the communication channel through the remote system to control the screen on the client device.5. The computer-implemented method of wherein sending control outputs comprises:sending content control outputs controlling content rendering on the browser.6. The computer- ...

AUTHENTICATION AND PAIRING OF DEVICES USING A MACHINE READABLE CODE

An MR code is generated within a browser on a client device and is read by a mobile application on a mobile device. A communication channel is then established through a web-based service, between the browser and the mobile application on the mobile device. The mobile application generates a user interface display on the mobile device that allows user selection of content. The mobile application sends a link to that content to the browser, which accesses and renders the content on the client device. User input commands to control the rendered content are also received at the mobile device and sent to the browser through the communication channel. 112-. (canceled)13. A computer-implemented method comprising:scanning, by a mobile device, a machine readable code (MR code) displayed on a second device;receiving, by the mobile device, authentication information associated with a user;authenticating, by a remote system, the user based on the authentication information; andenabling, by the remote system, a pairing between the mobile device and the second device that facilitates trusted communication between the mobile device and the second device.14. The computer-implemented method of claim 13 , and further comprising:generating, by the mobile device, a command to control the second device; andcommunicating, using the pairing, the command to the second device.15. The computer-implemented method of claim 13 , wherein the authentication information comprises a user credential.16. The computer-implemented method of claim 13 , wherein the remote system enables the pairing by:sending a communication to the mobile device based on the authentication information and information obtained by the mobile device from scanning the MR code.17. The computer-implemented method of claim 13 , wherein the second device receives content from the remote system and displays the content on a display screen of the second device.18. The computer-implemented method of claim 17 , wherein the content ...

FASTENER

A fastener for fastening an elongate object to a support structure, the fastener comprising a body portion formed entirely of one or more electrically non-conductive materials and comprising a bridge, a first column extending substantially perpendicularly from a first end of the bridge and a second column extending substantially perpendicularly from a second end of the bridge, the bridge and columns together forming a U-shaped receptacle for engaging the elongate object, and a nail formed entirely of one or more electrically non-conductive materials and partially contained within the first column of the body portion for positively engaging with the support structure upon the application of force by a driving mechanism thereby fastening the elongate object to the support structure. 1. A fastener for fastening an elongate object to a support structure , the fastener comprising:a body portion formed entirely of one or more electrically non-conductive materials and comprising a bridge, a first column extending substantially perpendicularly from a first end of the bridge and a second column extending substantially perpendicularly from a second end of the bridge, the bridge and columns together forming a U-shaped receptacle for engaging the elongate object, anda nail formed entirely of one or more electrically non-conductive materials and partially contained within the first column of the body portion for positively engaging with the support structure upon the application of force by a driving mechanism thereby fastening the elongate object to the support structure.2. A fastener according to in which the first column comprises a bore which partially contains the first nail within the first column of the body portion claim 1 , the bore of the first column contains a portion of the first nail adjacent an end of the nail for engaging with the support structure and the bore of the first column forms an interference fit with the portion of the first nail.36-. (canceled)7. A ...

System and method for retrieving registry data

Information is retrieved from the registry by creating a registry interface database containing information regarding registry data and uniquely identifying every registry entry for a registry interface. Source header files are generated using information about a program module, such as an application, contained in the registry interface database. The source header files are compiled with the application to generate the application's executable file. During run-time of the application, the registry interface is called by the application to retrieve registry data. If available, the registry interface retrieves the registry data and forwards this information to the application. In the event that the registry data is not available, the registry interface retrieves a default value in place of the registry data and forwards that default data to the application. A policy may be implemented by checking a policy area of the registry for the registry data and invoking the policy.

FASTENER SYSTEM

A fastener system comprising one or more fasteners and a fastener tool is disclosed. The fastener tool comprises a housing; an elongate magazine attached to the housing comprising an elongate partial surface between its ends configured to engage a support structure; a fastener carrying mechanism configured to carry the one or more fasteners with receptacles thereof accessible through the elongate partial surface; a pusher comprising a first end member and a second end member, the second end member providing a receptacle; and a location system formed from a receptacle of the one or more fasteners and the receptacle of the pusher second end member, each configured to locate the fastener tool over and in line with an elongate object on the support surface, and a drive system configured to drive a lead fastener to fasten the elongate object to the support surface.

ROTARY COMBUSTION APPARATUS

A combustion apparatus having a housing including an inner surface that defines at least one chamber, a rotor, a rotor shaft, an intake shaft, an exhaust shaft, and a gearing mechanism. The chamber includes an intake valve port and an exhaust valve port, and the rotor shaft is coupled to a gear at one end and has at least two opposing flat surfaces received by an opening in the rotor. The intake and exhaust shafts are geared to the rotor shaft and have at least one opening each that is aligned with the intake and the exhaust valve ports. A gearing mechanism selectively controls the duration in which the openings are aligned with the ports. Two or more rotors may be utilized to produce more power and reduce vibration.

SYSTEMS AND METHODS FOR THE MATCHING OF MATERIALS DATA TO PARTS DATA

Systems and methods for correlating materials records to part records. At least one materials record is provided with a corresponding digital materials images and a plurality of parts records are provided with at least one corresponding digital parts image. The materials records are automatically compared to the part records, and potential matches are identified. Any digital materials images and parts images for the potential matches are displayed to the user for confirmation of a match.

Reel

ENHANCED METADATA PERSISTANT USER INTERFACE NAVIGATION

A method and apparatus receive a user login and first menu selections through a graphic user interface of a multi-function printing device. The method processes one or more first sheets through a document handler of the multi-function printing device by following the first menu selections. Once finished processing the first sheet (or set of sheets) through the document handler, the method can then receive different (second) menu selections from the user. Then, the method processes one or more second sheets through the document handler by following the second menu selections. In order to provide greater ease of use, the methods herein present the user with an option to revert back to any of the previous menu selections (e.g., the first menu selections) through the graphic user interface. If the user chooses to revert to the first menu selections, the methods herein can process one or more third sheets through the document handler of the multi-function printing device by following the first ...

CONVERSION OF PLASTICS TO MONOMERS BY ACIDIC CATALYTIC PYROLYSIS

A plastic catalytic pyrolysis process that can produce high yields of ethylene, propylene and other light olefins from waste plastics is disclosed. The plastic feed is catalytically pyrolyzed at high silica-to-alumina ratios and elevated temperature to produce high ratios of gas to liquid which results in high light olefin monomer selectivity. The catalytic pyrolysis process can be operated in a single stage or a two-stage process.

Systems and methods for exporting auto finance information

This disclosure relates generally to systems and methods for providing personalized financing information and, more particularly, systems and methods for providing personalized financing information via a dealership website using an API associated with a financial service provider. In one embodiment, a system includes memory hardware storing instructions that configure processing hardware to receive a loan request for a buyer via a real-time API that includes at least buyer identification and financial information and information associated at least one inventory item presented on a dealership website. The system may also determine financing information comprising prospective financing terms for the at least one item based on at least the loan request. The server may also provide, to the dealership server via the real-time API, the determined financing information for presentation on the dealership website, including prospective financing terms information corresponding to each of the at ...

AUTHENTICATION AND PAIRING OF DEVICES USING A MACHINE READABLE CODE

An MR code is generated within a browser on a client device and is read by a mobile application on a mobile device. A communication channel is then established through a web-based service, between the browser and the mobile application on the mobile device. The mobile application generates a user interface display on the mobile device that allows user selection of content. The mobile application sends a link to that content to the browser, which accesses and renders the content on the client device. User input commands to control the rendered content are also received at the mobile device and sent to the browser through the communication channel. 120-. (canceled)21. A method performed by a computing system , the method comprising:receiving a request to establish a computing session between a first computing device and a second computing device, the request being associated with a user;based on the request, sending an instruction over a communication network to display a machine readable (MR) code in association with the first computing device;receiving an indication that the second computing device scanned the displayed MR code;based on the indication, generate an instruction to establish the computing session; andsending, in association with the established computing session, content from the computing system to the second computing device through the communication network.22. The method of claim 21 , and further comprising:receiving a user credential associated with the user; andauthenticating the user based on the user credential.23. The method of claim 22 , and further comprising:based on the authentication, generating the instruction to establish the computing session.24. The method of claim 22 , and further comprising:based on the authentication, sending the MR code to the first computing device.25. The method of claim 21 , wherein the computing system comprises a remote server that is remote from both the first and second computing devices.26. The method of ...

Exercise bicycle

An exercise bicycle including a body that supports a seat and handle bars. Supported by the body is a crank assembly. The crank assembly includes a shaft and crank arm that are variable in length. 1. An exercise bicycle , comprising:a body to engage a supporting surface to prevent movement of the exercise bicycle relative to the support surface during use of the exercise bicycle; anda crank assembly including a crank shaft mounted in the body for rotation about a generally horizontal crank axis, a pair of crank arms fixed to the shaft at locations spaced longitudinally of the shaft, the arms extending from the shaft in opposite directions, a pedal mounted in each arm at a location spaced from the shaft, each pedal being rotatable about a pedal axis that is generally parallel to the crank axis, and wherein each pedal is positioned at a length from the shaft, the lengths being adjustable by operation of the arms.2. The bicycle of claim 1 , wherein each arm includes a first member and a second member claim 1 , the members being telescopically associated and including securing means to fix the members together to provide said length.3. The bicycle of claim 2 , wherein said first member is hollow and said second member is telescopically received within said first member claim 2 , said first member having a series of apertures and said second member having a projection to engage within a respective one of the apertures to provide said length.4. The bicycle of wherein the apertures are arranged in two sets with the second member being located between the sets claim 3 , the projection is a first projection claim 3 , and the second member includes a second projection claim 3 , each projection being operatively associated with a repeat of the sets.5. The bicycle of wherein each projection is movable between a retracted position and an extended position engaged in a selected aperture to secure the first and second members together claim 4 , thereby providing for length ...

Fastener

Authentication and pairing of devices using a machine readable code

An MR code is generated within a browser on a client device and is read by a mobile application on a mobile device. A communication channel is then established through a web-based service, between the browser and the mobile application on the mobile device. The mobile application generates a user interface display on the mobile device that allows user selection of content. The mobile application sends a link to that content to the browser, which accesses and renders the content on the client device. User input commands to control the rendered content are also received at the mobile device and sent to the browser through the communication channel.

Expandable Tip Delivery System and Method

A method of deploying a stent-graft in a curved vessel includes deploying an expandable tip to center a proximal end of the catheter containing a stent-graft in the curved vessel. A sheath is retracted to expose the stent-graft and the stent-graft self-expands into the curved vessel. By centering the catheter containing the stent-graft prior to deployment with the expandable tip, the accuracy of stent graft placement within the curved vessel is improved.

Dye Injected Request Generation

Web server processes can host multiple web applications that process multiple requests from multiple clients. Recorded diagnostic information may not provide a useful separation of server execution data (e.g., functionality executed to process a request) based on a client's use of the web server process. An effective method for separating server execution data by client information is provided herein. Dye is injected into a request from a client, the dye comprises information regarding the client application making the request and a transaction (e.g., client defined set of requests) that the request is comprised within. The dye injected request is sent to a web server process (e.g., on a web server) that extracts the dye and executes the request. During execution of the request, executed functionality is associated and stored with the extracted dye. The recorded server execution data may be organized based upon the request, client, application, and/or transaction.

METHOD AND APPARATUS FOR TINNITUS EVALUATION

Methods, articles of manufacture, and systems for evaluating tinnitus are disclosed herein. According to various embodiments, a tinnitus evaluation system may include a tinnitus evaluation module configured to perform one or more tinnitus evaluation tests. A tinnitus evaluation test may comprise generating a first single-frequency sound based at least in part on a sound of a patient's tinnitus, and generating a narrow-band sound centered at the frequency of the first single-frequency sound. Tests include a hearing threshold test, a loudness match test, a pitch match test, a bandwidth match test, a minimum masking level test, and a residual inhibition test. 1. An apparatus for evaluating tinnitus , comprising:at least one stimulus generator configured to generate a first single-frequency sound based at least in part on a pitch of a patient's tinnitus, the stimulus generator further configured to generate a narrow-band sound centered at the frequency of the first single-frequency sound.2. The apparatus of claim 1 , wherein the stimulus generator is configured to generate octave band pass noises and fixed-width narrow-band noises.3. The apparatus of claim 1 , wherein the stimulus generator comprises one or more devices selected from a group consisting of a programmable oscillator claim 1 , a programmable state variable filter claim 1 , a programmable noise source claim 1 , and an analog multiplier.4. The apparatus of claim 1 , further comprising a computing apparatus interface for coupling the apparatus to a computing apparatus.5. The apparatus of claim 4 , wherein the stimulus generator is configured to generate sounds based at least in part on instructions received from the computing apparatus.6. The apparatus of claim 1 , further comprising a user interface for allowing the patient to selectively control the sounds generated by the stimulus generator.7. The apparatus of claim 1 , further comprising a signal preamplifier configured to selectively modify sounds ...

Boat

Voltage measurement circuit with AC-coupled diferential amplifier

A voltage measurement circuit is provided, which is has an AC-coupled differential amplifier coupled to first and second input terminals for measuring a voltage across the first and second input terminals. The AC-coupled differential amplifier blocks a DC component of the voltage and presenting a low input bias current to the first and second input terminals while isolating the first and second input terminals from charge stored in capacitances in the AC-coupled differential amplifier.

SYSTEMS AND METHODS FOR EXPORTING AUTO FINANCE INFORMATION

This disclosure relates generally to systems and methods for providing personalized financing information and, more particularly, systems and methods for providing personalized financing information via a dealership website using an API associated with a financial service provider. In one embodiment, a system includes memory hardware storing instructions that configure processing hardware to receive a loan request for a buyer via a real-time API that includes at least buyer identification and financial information and information associated at least one inventory item presented on a dealership website. The system may also determine financing information comprising prospective financing terms for the at least one item based on at least the loan request. The server may also provide, to the dealership server via the real-time API, the determined financing information for presentation on the dealership website, including prospective financing terms information corresponding to each of the at least one item. 120.-. (canceled)21. A financial service system for providing personalized financing information determinations , comprising:memory hardware storing instructions; and providing an Application Programming Interface (API) that is accessible by a dealership server and configured to provide personalized financing information determinations to the dealership server;', personal identification information of the buyer;', 'personal financial information of the buyer; and', 'information associated with an inventory item listed on the dealership website;, 'receiving, from the dealership server, a loan request from a buyer via a dealership website associated with the dealership server, the loan request comprising, the inventory item;', 'the personal identification information of the buyer; and', 'the personal financial information of the buyer;, 'generating a personalized financing information determination based on the received loan request, the determination comprising ...

Method and system of session media negotiation

Methods and systems for processing a signaling message are disclosed. An exemplary method comprises: determining a first transcoding policy associated with an originator endpoint contained in a received first call offer; determining a second transcoding policy associated with an answerer endpoint contained in the first call offer; applying the first transcoding policy to a first offer codec set in the first call offer to produce a second call offer containing a second offer codec set; applying the second transcoding policy to the second codec set to produce a third call offer containing a third offer codec set; comparing a first answerer codec set in a received first answer and a second answerer codec set contained in the second call offer; and determining whether or not to perform transcoding based on a result of the comparison.

SAMPLE TUBE AND METHOD

A sample tube includes a barcode split into components at the bottom of the sample tube. Each barcode component stores less than the full data output from the barcode, but the components combine to full data output. Redundant diagonal components provide for error checking. A center region between the barcode components supports an electrical circuit or an optical or acoustic window. The sample tube may have a sidewall with a substantially cylindrical open end and non-cylindrical end closed with a bottom, the non-cylindrical end orienting the sample tube in a rack. Additional non-cylindrical surfaces are provided to orient the sample tube relative to complementary surfaces at a gripper. The sample tube of a particular application is positioned in an acoustic dispensing system where acoustic waves are transmitted through a center window for surveying and dispensing. 1. A sample tube comprising:a sidewall that is substantially cylindrical and open at one end and non-cylindrical and closed with a bottom at the opposite end; andnon-cylindrical surfaces formed in the substantially cylindrical end of the sidewall to be gripped by complementary gripper surfaces of a gripper, assuring proper orientation of the test tube relative to the gripper.2. The sample tube as recited in wherein the bottom end of the sample tube has a rectangular cross-section.3. The sample tube as recited in wherein the non-cylindrical surfaces formed in the substantially cylindrical end of the sidewall extend along the edges of the rectangular section at the bottom end of the sample tube.4. The sample tube of wherein the non-cylindrical surfaces are flat surfaces.5. The sample tube as recited in further comprising a barcode on the bottom end of the sample tube claim 1 , the barcode including an element to determine the orientation of the sample tube.6. The sample tube as recited in further comprising a protrusion or depression on the sidewall to orient the sample tube.7. A method of orienting sample ...

Determining high toner usage

According to a method herein, a number of pixels marked and times of printing are automatically determined for a plurality of images. A time-based moving window of pixel counts for a subset of the plurality of images being contiguously processed in a current time window is automatically calculated, based on the number of pixels marked and the times of printing of the subset of the plurality of images processed in the current time window. Marking material usage to print the plurality of images for the current time window is automatically determined, based on the time-based moving window of pixel counts of the current time window. The method automatically determines if the marking material usage for the current time window exceeds a threshold. A notification is automatically output if the marking material usage for the current time window exceeds the threshold.

Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives

The present invention provides methods and compositions for preparing 4-substituted 3-hydroxybutyric acid derivatives by halohydrin dehalogenase-catalyzed conversion of 4-halo-3-hydroxybutyric acid derivatives. The present invention further provides methods and compositions for preparing 4-halo-3-hydroxybutyric acid derivatives by ketoreductase-catalyzed conversion of 4-halo-3-ketobutyric acid derivatives The present invention also provides methods and compositions for preparing vicinal cyano, hydroxyl substituted carboxylic acid esters.

Crop weighing

A method of determining the weight of animals and the development of plants in a controlled environment. The method includes measuring the increase in CO2 production over a test period. CO2 production is a measure of the metabolic rate and this is related to weight of animals and development of crops which can often be determined by weight. There is illustrated a poultry rearing house having vents, lights and an air heater. CO2 sensors are connected to a CO2 controller and in turn to a central controller. To test the increase in CO2 production over time, the birds are settled into a passive state with no feed and the lights turned off. The level of CO2 produced is measured. The vents are closed. After a time, the rate of Co2 produced is measured and the increase calculated.

Method and apparatus for tinnitus evaluation

Methods, articles of manufacture, and systems for evaluating tinnitus are disclosed herein. According to various embodiments, a tinnitus evaluation system may include a tinnitus evaluation module configured to perform one or more tinnitus evaluation tests. A tinnitus evaluation test may comprise generating a first single-frequency sound based at least in part on a sound of a patient's tinnitus, and generating a narrow-band sound centered at the frequency of the first single-frequency sound. Tests include a hearing threshold test, a loudness match test, a pitch match test, a bandwidth match test, a minimum masking level test, and a residual inhibition test.

Method and structure for nasal dilator

A nasal dilator and method of making nasal dilators are provided. The dilator may have a composite base element of at least two regions, the base element having an outer surface and an inner surface, the inner surface of the base element having a pressure-sensitive adhesive disposed thereon; the base element further including a spring element which imparts return memory into the base element so that the base element returns towards a planar conformation during use. The spring element has elastic memory effected by differential properties in the at least two regions.

Authentication and pairing of devices using a machine readable code

An MR code is generated within a browser on a client device and is read by a mobile application on a mobile device. A communication channel is then established through a web-based service, between the browser and the mobile application on the mobile device. The mobile application generates a user interface display on the mobile device that allows user selection of content. The mobile application sends a link to that content to the browser, which accesses and renders the content on the client device. User input commands to control the rendered content are also received at the mobile device and sent to the browser through the communication channel.

Device for refilling a fuel cartridge for a fuel cell

A refillable fuel supply assembly for a fuel cell is disclosed herein. The assembly includes a refillable fuel supply adapted to supply fuel to a fuel cell, a refilling fuel cartridge containing fuel to be transferred to the refillable fuel supply, and a lock-and-release device connecting the refilling fuel cartridge to the refillable fuel supply to transport fuel from the refilling fuel cartridge to the refillable fuel supply. The lock-and-release device also retains the refilling fuel cartridge to the refillable fuel supply until the refilling fuel cartridge is substantially free of fuel.

Portable knowledge format for the distribution of content

The present invention relates to systems and methods for facilitating the movement of content using a portable knowledge format data structure. The portable knowledge format data structure of the present invention comprises one or more items of content. The portable knowledge format data structure further comprises metadata corresponding to the one or more items of content. The data structure maintains an index corresponding to the one or more items of content, as well as an indication of a hierarchy among the one or more items of content.

Equipment documentation management system, method, and software tools

Methods, software tools and systems are provided for facilitating management of equipment data and documentation in plants. Data on plant equipment is extracted from plant enterprise resource planning or similar systems and formed into a structured hierarchical tree. The tree relates to a database which acts as a template of the data and documents expected to be associated with the equipment Auditors use this data structure to audit the equipment collect documents and generate electronic versions of the documents. An assessor tool allows plants to select and parse the documents into elements such as diagrams, bills of materials, text, etc., and to select how these elements are to be processed. The assessed content is uploaded to a conversion network which manages a network of vendors who perform the processing in accordance with a workflow controlled by the conversion network. The processed structured content is reaggregated and indexed in the equipment tree. An equipment data and documentation ...

Portable temperature controlled container

This invention relates to a portable temperature controlled container comprising a body having a storage compartment, an opening to permit access to the storage compartment and an insulated lid. The container comprises a fan, a heat sink and a first thermoelectric device, as well as a first phase change material and a second thermoelectric device in thermal communication with both the first phase change material and the storage compartment. The second thermoelectric device in thermal communication with both the first phase change material and the storage compartment is operable to transfer energy in the form of heat between the storage compartment and the first phase change material. The thermoelectric devices can be Peltier elements.

Radiology device

A radiology device includes at least one gamma radiation sensor, an acquisition device arranged to acquire data from each gamma radiation sensor, a transmission device arranged to transmit the acquired data outside the device, at least one battery arranged to store electrical energy and to electrically supply each sensor, the acquisition device and the transmission device. The radiology device is arranged to be carried entirely by the user. An application of the present radiology device is the treatment of cancers by administration of radionuclides.

System and Method for Selective Automatic Electronic Access of Personal Data

A system and method for selective automatic electronic access to personal data. A content distribution system server having a relational database and user navigation facility is accessible via the Internet. Users create memberships and designate recipients, method of delivery, recipient-specific content, and triggering events, and upload this information to the content distribution system server.

OIL BODY EXTRACTION AND USES

The present invention provides a method of extracting naturally occurring oil bodies comprising obtaining material containing naturally occurring oil bodies, recovering the oil bodies in a wet preparation and drying the oil bodies; and dried oil bodies obtained by the method and uses thereof. 1. A method of extracting naturally occurring oil bodies comprising:(i) obtaining material containing naturally occurring oil bodies;(ii) recovering the oil bodies in a wet preparation;(iii) drying the oil bodies.2. The method of wherein the dried oil bodies have a water activity of less than 0.3.3Euglena.. The method of wherein the material containing the naturally occurring oil bodies is selected from one or more of seeds claim 1 , pollen claim 1 , flowers claim 1 , roots and stems of flowering plants claim 1 , the spores and vegetative organs of non-flowering plants claim 1 , algae claim 1 , microalgae claim 1 , animal cells claim 1 , fungi and protists such as4. The method of wherein the seeds are seeds or kernels from one or more of the following plants claim 3 , sunflower claim 3 , soybean claim 3 , oil palm claim 3 , safflower claim 3 , almond claim 3 , macadamia claim 3 , cotton seed claim 3 , ground nut claim 3 , coconut claim 3 , oil seed rape claim 3 , echium claim 3 , borage claim 3 , linseed/flax/hemp claim 3 , evening primrose claim 3 , rice claim 3 , wheat claim 3 , oat claim 3 , maize and barley.5. The method of wherein the oil bodies contain triacylglycerol molecules enriched in unsaturated fatty acids6. The method of wherein the oil bodies contain omega-3 or other essential fatty acids7. The method of wherein the oil bodies are spray dried.8. The method of wherein before drying the oil bodies a carrier is added to the wet preparation.9. The method of wherein the carrier is a protein or a sugar.10. The method of wherein the carrier is maltodextrin.11. The method of wherein the dried oil bodies are in a powder form.12. The method of wherein the dried oil bodies ...

METHOD AND STRUCTURE FOR NASAL DILATOR

A nasal dilator and method of making nasal dilators are provided. The dilator may have 2. The nasal dilator of wherein the base element comprises one or more composite regions having differential properties therein.3. The nasal dilator of claim 1 , wherein the base element comprises at least one shrink material.4. The nasal dilator of claim 1 , wherein at least one of the at least two regions of the base element is located on the outer surface of the base element.6. The nasal dilator of claim 5 , wherein at least one of the first material or second material of the base element comprises a shrink material.7. The nasal dilator of claim 6 , wherein the shrink material is a shrink film.8. The nasal dilator of claim 6 , wherein elastic memory in the spring element has been induced by heating the base element.9. The nasal dilator of claim 5 , wherein the first material and second material comprise materials with different degrees of permanent deformation upon heating.10. The nasal dilator of claim 5 , wherein the first material and second material comprise materials with different rates of contraction upon cooling.11. The nasal dilator of claim 5 , wherein the base element is an extruded composition or coextruded layers of differing compositions.12. The nasal dilator of claim 5 , wherein the base element is a laminate.14. The method of claim 13 , wherein the physical treatment comprises application of thermal energy or radiation.15. The method of claim 13 , wherein the different physical characteristics of the two materials comprises different degrees of permanent deformation upon heating.16. The method of wherein the different physical characteristics are different degrees of shrinkage after coextrusion.17. The method of claim 13 , wherein at least one of the materials is a shrink material.18. The method of claim 13 , wherein at least one of the materials is a shrink film.19. The method of claim 13 , wherein base element is formed by coextrusion of two differing ...

AUTHENTICATION AND PAIRING OF DEVICES USING A MACHINE READABLE CODE

An MR code is generated within a browser on a client device and is read by a mobile application on a mobile device. A communication channel is then established through a web-based service, between the browser and the mobile application on the mobile device. The mobile application generates a user interface display on the mobile device that allows user selection of content. The mobile application sends a link to that content to the browser, which accesses and renders the content on the client device. User input commands to control the rendered content are also received at the mobile device and sent to the browser through the communication channel. 112-. (canceled)13. A client computing device comprising:a wireless communication interface;at least one processor; and display a machine readable code (MR code);', 'establish a secure communication channel with the mobile computing device by pairing the mobile computing device and the client computing device based on user authentication by a remote computing system; and', 'based on an indication that a mobile computing device, that is separate from the client computing device, scanned the displayed MR code,'}, 'receive content associated with the remote computing system through the secure communication channel using the wireless communication interface., 'memory storing instructions executable by the at least one processor, wherein the instructions, when executed, configure the client computing device to14. The client computing device of claim 13 , wherein the user authentication is performed by the remote computing system based on a user credential that is input by a user using the mobile computing device.15. The client computing device of claim 13 , wherein the MR code is displayed on a display screen of the client computing device.16. The client computing device of claim 15 , wherein the content comprises content other than the MR code claim 15 , and the instructions configure the client computing device to:display the ...

Service path routing between session border controllers

Systems and methods of establishing IP telephony sessions between enterprises are disclosed. A first enterprise requests an association with a second enterprise. Both enterprises and the second enterprise belong to the same federation. The association request is accepted, to establish an association between the first and second enterprises. In response to the acceptance, a direct routed path is established between the first enterprise and the second enterprise. One of the associated enterprises requests activation of an IP telephony service. If the request to activate references the association, an IP telephony session is established using the direct routed path.

Soups and pasta dishes

Dry soup and pasta dish mixes having a combination of ingredients which permit the formulator to continue to provide good organoleptic properties while at the same time reducing the caloric impact for those consumers who desire to limit their caloric intake. The soup and pasta mixes preferably include 250 or fewer calories, especially 245 or fewer calories, most preferably 225, 220 or fewer calories. Preferably the product includes agglomerated protein and is fortified with vitamins and minerals.

Dye injected request generation

Web server processes can host multiple web applications that process multiple requests from multiple clients. Recorded diagnostic information may not provide a useful separation of server execution data (e.g., functionality executed to process a request) based on a client's use of the web server process. An effective method for separating server execution data by client information is provided herein. Dye is injected into a request from a client, the dye comprises information regarding the client application making the request and a transaction (e.g., client defined set of requests) that the request is comprised within. The dye injected request is sent to a web server process (e.g., on a web server) that extracts the dye and executes the request. During execution of the request, executed functionality is associated and stored with the extracted dye. The recorded server execution data may be organized based upon the request, client, application, and/or transaction.

Gaming systems and methods

The invention relates generally to methods and apparatus for playing games involving numbers or symbols, including but not limited to the classic game of BINGO. More particularly, the methods and apparatus relate to games involving matrices or arrays of numbers or symbols and different techniques and/or equipment used when playing the games, which help define how the games are won.

PLASTICS PYROLYSIS PROCESS WITH QUENCH

A plastic catalytic pyrolysis process that can produce high yields of ethylene, propylene and other light olefins from waste plastics is disclosed. The catalytic product stream is quenched to below catalytic pyrolysis temperature quickly after exiting the reactor or bulk separation from the catalyst. Quench preserves selectivity of light olefinic monomers. The catalytic pyrolysis process can be operated in a single stage or a two-stage process.

SYSTEMS AND METHODS FOR EXPORTING AUTO FINANCE INFORMATION

This disclosure relates generally to systems and methods for providing personalized financing information and, more particularly, systems and methods for providing personalized financing information via a dealership website using an API associated with a financial service provider. In one embodiment, a system includes memory hardware storing instructions that configure processing hardware to receive a loan request for a buyer via a real-time API that includes at least buyer identification and financial information and information associated at least one inventory item presented on a dealership website. The system may also determine financing information comprising prospective financing terms for the at least one item based on at least the loan request. The server may also provide, to the dealership server via the real-time API, the determined financing information for presentation on the dealership website, including prospective financing terms information corresponding to each of the at least one item. 1. A financial service system for providing personalized financing information for incorporation into a dealership website , comprising:memory hardware storing instructions; and receive, from a dealership server via an Application Programming Interface (API) configured to provide real-time financing information determinations, a loan request submitted to the dealership server via the dealership website, the loan request including at least buyer identification information, buyer financial information, and one or more buyer loan preferences;', 'receive, in real-time from the dealership server and in response to the buyer selecting a vehicle from the inventory listing, vehicle information associated with the selected vehicle;', 'determine financing information in response to the buyer selection based on the buyer financial information, received vehicle information, and the one or more buyer loan preferences, comprising prospective financing terms for the selected ...

Generating and rendering electronic business cards

Graphical visual representations of electronic business cards may be generated from associated contact file information. Electronic business cards may be sent and received over digital media. Contacts information associated with received electronic business cards may be used for adding to or updating information contained in a recipient's electronic contact files.

Sample tube and method

A sample tube includes a barcode split into components at the bottom of the sample tube. Each barcode component stores less than the full data output from the barcode, but the components combine to full data output. Redundant diagonal components provide for error checking. A center region between the barcode components supports an electrical circuit or an optical or acoustic window. The sample tube may have a sidewall with a substantially cylindrical open end and non-cylindrical end closed with a bottom, the non-cylindrical end orienting the sample tube in a rack. Additional non-cylindrical surfaces are provided to orient the sample tube relative to complementary surfaces at a gripper. The sample tube of a particular application is positioned in an acoustic dispensing system where acoustic waves are transmitted through a center window for surveying and dispensing.

AUTHENTICATION AND PAIRING OF DEVICES USING A MACHINE READABLE CODE

An MR code is generated within a browser on a client device and is read by a mobile application on a mobile device. A communication channel is then established through a web-based service, between the browser and the mobile application on the mobile device. The mobile application generates a user interface display on the mobile device that allows user selection of content. The mobile application sends a link to that content to the browser, which accesses and renders the content on the client device. User input commands to control the rendered content are also received at the mobile device and sent to the browser through the communication channel.

Methods and apparatus for performing diagnostics of web applications and services

A method and apparatus for performing a diagnostic of a web based client server application. The web based client server application comprising a web application code, a web application framework, a web server, and a web client. The method comprising an act of collecting diagnostic data associated with the execution of the web application code, wherein the method of performing the diagnostic of the web based client server application adapts to a type of the web server. In another embodiment, marking the beginning and/or end of a diagnostic session, during which diagnostic data associated with the execution of the web application code is collected, is performed based on a launch of the web client. In a further embodiment, determining information about the web application code at least partially based on an interaction with the web application framework. In another embodiment, determining a type of the web server and starting the web server at least partially based on the determined type ...

METHOD AND APPARATUS FOR TINNITUS EVALUATION

Methods, articles of manufacture, and systems for evaluating tinnitus are disclosed herein. According to various embodiments, a tinnitus evaluation system may include a tinnitus evaluation module configured to perform one or more tinnitus evaluation tests. A tinnitus evaluation test may comprise generating a first single-frequency sound based at least in part on a sound of a patient's tinnitus, and generating a narrow-band sound centered at the frequency of the first single-frequency sound. Tests include a hearing threshold test, a loudness match test, a pitch match test, a bandwidth match test, a minimum masking level test, and a residual inhibition test.

METHODS AND SYSTEMS FOR PROVIDING PERSONALIZED, REAL-TIME INFORMATION BASED ON REMOTELY RETRIEVED INFORMATION

This disclosure relates generally to systems and methods for providing personalized financing information and, more particularly, systems and methods for providing personalized financing information via a dealership website using an API associated with a financial service provider. In one embodiment, a system includes memory hardware storing instructions that configure processing hardware to receive a loan request for a buyer via a real-time API that includes at least buyer identification and financial information and information associated at least one inventory item presented on a dealership website. The system may also determine financing information comprising prospective financing terms for the at least one item based on at least the loan request. The server may also provide, to the dealership server via the real-time API, the determined financing information for presentation on the dealership website, including prospective financing terms information corresponding to each of the at ...

Cable clip

Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives

The present invention provides methods and compositions for preparing 4-substituted 3-hydroxybutyric acid derivatives by halohydrin dehalogenase-catalyzed conversion of 4-halo-3-hydroxybutyric acid derivatives. The present invention further provides methods and compositions for preparing 4-halo-3-hydroxybutyric acid derivatives by ketoreductase-catalyzed conversion of 4-halo-3-ketobutyric acid derivatives.

Method and Structure for Nasal Dilator

A nasal dilator and method of making nasal dilators are provided. The dilator may have 1. A laminated material having a longitudinal length and a longitudinal width , the laminated material comprising:a first material comprising a heat activated polyester shrink film laminated to a second material comprising a polymeric film, wherein the first material and second material have differing shrink properties when exposed to heat such that the first material, upon heat activation, shrinks at a greater ratio than the second material;wherein said heat activation occurs above ambient temperature;wherein the longitudinal length of the laminated material has a curvature in the shape of an arc about the longitudinal width,wherein the shape of the arc is induced by cooperation between the first material and second material upon heat activation of the first material, andwherein the first material is on the concave side of the arc and the second material is on the convex side of the arc.2. The laminated material of claim 1 , wherein the heat activated polyester shrink film is a heat activated polyethylene terephthalate shrink film.3. The laminated material of claim 1 , wherein the second material comprises polyester.4. The laminated material of claim 3 , wherein the polyester is polyethylene terephthalate. This application is a continuation of U.S. patent application Ser. No. 13/175,024 filed Jul. 1, 2011 which claims the benefit of U.S. Provisional Application No. 61/398,949 filed on Jul. 2, 2010. The entirety of each of these applications is hereby incorporated by reference for all purposes.1. Field of the InventionThe present invention relates to the field of nasal patches or nasal dilators that assist in keeping the exterior nasal passages open to assist in breathing and/or avoiding snoring. A process, structure, and composition of elements which assist in providing necessary or useful properties for the nasal dilator are provided.2. Background of the ArtNasal DilatorsNasal ...

Sending and receiving electronic business cards

Graphical visual representations of electronic business cards may be generated from associated contact file information. Electronic business cards may be sent and received over digital media. Contacts information associated with received electronic business cards may be used for adding to or updating information contained in a recipient's electronic contact files.

Control wellhead buoy

The present invention relates to a subsea system for the production of hydrocarbon reserves. More specifically, the present invention relates to a subsea system in economically and technically challenging environments. Still more specifically, the present invention relates to a control wellhead buoy that is used in deepwater operations for offshore hydrocarbon production.

Service Path Routing Between Session Border Controllers

Systems and methods of establishing IP telephony sessions between enterprises are disclosed. A first enterprise requests an association with a second enterprise. Both enterprises and the second enterprise belong to the same federation. The association request is accepted, to establish an association between the first and second enterprises. In response to the acceptance, a direct routed path is established between the first enterprise and the second enterprise. One of the associated enterprises requests activation of an IP telephony service. If the request to activate references the association, an IP telephony session is established using the direct routed path.

GENE EDITING OF MONOGENIC DISORDERS IN HUMAN HEMATOPOIETIC STEM CELLS -- CORRECTION OF X-LINKED AGAMMAGLOBULINEMIA (XLA)

In certain embodiments methods of treating X-Linked agammaglobulinemia (XLA) in a mammal are provided where the methods comprise: i) providing differentiated T cells and/or stem/progenitor cells from the mammal; ii) performing a targeted insertion of a corrective BTK cDNA at the BTK gene locus in said cells to provide a corrected BTK gene in said cells; and iii) introducing said cells into said mammal where said corrected BTK gene is expressed in a physiologically regulated manner.

Plastics pyrolysis process with quench

A plastic catalytic pyrolysis process that can produce high yields of ethylene, propylene and other light olefins from waste plastics is disclosed. The catalytic product stream is quenched to below catalytic pyrolysis temperature quickly after exiting the reactor or bulk separation from the catalyst. Quench preserves selectivity of light olefinic monomers. The catalytic pyrolysis process can be operated in a single stage or a two-stage process.

SELF-BALANCING, STABLE BEVERAGE CONTAINER SUPPORT

A cup-holder includes a side-of-the-cup supporting element for supporting a cup. The side-of-the-cup supporting element has contact with the side(s) of the beverage container at at least three points distributed around the side(s) of the beverage container. The contact points may be continuous or discontinuous. The points of contact are provided by a side-contact element that that bridges at least the 200° of circumference and has a vertical support element that provides direct support to the side contact element. The three points of contact also must be at a height of the beverage container that is at least 25% upward along the height of the container, and preferably above the center of gravity of a liquid-filled beverage container to provide vertical rotational stability to the system described herein. 1. A side supporting element to temporarily support a beverage holder with liquid therein comprising:a) a solid material having an inner and outer surface and a top and a bottom, the solid material having curvature therein that will slide over the bottom of a beverage holder and grasp sides of the beverage holder at a position at least forty percent of the length of sides on a beverage holder grasped by the solid material.;b) the inner surface of the side supporting element having at least three contact points thereon or a continuous surface that will grasp the sides of the beverage holder, wherein the at least three contact points are distributed over at least 200 degrees of circumference of the inner surface of the solid material;c) the side supporting element having at least one extending element that can pass beyond a top of a beverage holder grasped by the side supporting element, andd) the at least one extending element having a surface connecting element at a distal end of the at least one extending element that can directly attach to a flat surface and support the solid material.2. The element of wherein the solid material comprises a cuff shaped to engage a ...

SAMPLE TUBE AND METHOD

A sample tube includes a barcode split into components at the bottom of the sample tube. Each barcode component stores less than the full data output from the barcode, but the components combine to full data output. Redundant diagonal components provide for error checking. A center region between the barcode components supports an electrical circuit or an optical or acoustic window. The sample tube may have a sidewall with a substantially cylindrical open end and non-cylindrical end closed with a bottom, the non-cylindrical end orienting the sample tube in a rack. Additional non-cylindrical surfaces are provided to orient the sample tube relative to complementary surfaces at a gripper. The sample tube of a particular application is positioned in an acoustic dispensing system where acoustic waves are transmitted through a center window for surveying and dispensing.

Expandable tip delivery system and method

A method of deploying a stent-graft in a curved vessel includes deploying an expandable tip to center a proximal end of the catheter containing a stent-graft in the curved vessel. A sheath is retracted to expose the stent-graft and the stent-graft self-expands into the curved vessel. By centering the catheter containing the stent-graft prior to deployment with the expandable tip, the accuracy of stent graft placement within the curved vessel is improved.

A PORTABLE TEMPERATURE CONTROLLED CONTAINER

This invention relates to a portable temperature controlled container comprising a body having a storage compartment, an opening to permit access to the storage compartment and an insulated lid. The container comprises a fan, a heat sink and a thermoelectric device, as well as a first phase change material and a thermoelectric device in thermal communication with both the first phase change material and the storage compartment. The thermoelectric device in thermal communication with both the first phase change material and the storage compartment is operable to remove energy in the form of heat from one of the storage compartment and the first phase change material and transfer that energy in the form of heat to the other of the storage compartment and the first phase change material. In this way, the device will require less power, be highly robust, will operate across a range of temperatures, and will be cost effective to manufacture. 1. A portable temperature controlled container comprising:a body having an outer shell, an inner shell and an insulation layer therebetween, the body defining a storage compartment and an opening to permit access to the storage compartment;an insulated lid selectively covering the opening in the body;a first thermoelectric device in thermal communication with the storage compartment;a first phase change material in thermal communication with the first thermoelectric device;a rechargeable battery;a temperature sensor operable to measure the temperature inside the storage compartment;a controller in communication with the thermoelectric device and the temperature sensor, the controller being operable to control the thermoelectric device to regulate the temperature inside the storage compartment; and in whichthe thermoelectric device is operable to remove energy in the form of heat from one of the storage compartment and the first phase change material and transfer that energy in the form of heat to the other of the storage compartment ...

Prosthesis Fixation Apparatus and Methods

A tubular prosthesis comprises a tubular graft; and an undulating stent having a plurality of apexes, a first end defined at least in part by a first group of the apexes, and a second end defined at least in part by a second group of the apexes, the first group of apexes being pivotally attached to the tubular graft so as to form a plurality of circumferentially arranged hinges about which the stent can pivot so that the second group of apexes can move between a position where they are inside the tubular graft and a position where they are outside the tubular graft. In one embodiment a tubular prosthesis comprises a tubular graft having a first end margin, a second end margin and a central portion therebetween; and an undulating stent having a plurality of apexes, a first end defined at least in part by a first group of the apexes, and a second end defined at least in part by a second group of the apexes, the undulating stent being secured to the tubular graft in a manner such that it can ...

Squeegee handle assembly

A squeegee handle assembly for holding a squeegee applicator. The handle assembly has a tubular body, an externally lipped opening and a stabilizing structure. The stabilizing structure is disposed on the inner wall of the tubular body opposite the externally lipped opening. A pair of end caps are provided to engage the ends of the tubular handle body. The handle assembly is constructed and arranged to trap a portion of the squeegee applicator within the tubular body without impairing the function of the exposed squeegee applicator blade during use.

Bus interface

A computer architecture that includes a high speed, low pin bus that directly couples a microprocessor to the physical memory of the processor. Physical memory typically has a number of dynamic random access memory (DRAM) devices. The bus is a byte wide and has a data rate of approximately 500 Mbytes/sec. The high speed bus may be coupled with a conventional bus, so that conventional devices can communicate with the processor using existing bus protocols. The present invention includes a processor interface that allows the processor to communicate using the protocol of either bus. The interface also allows communication between devices on either bus. Also included is a system that incorporates cache memory on a high speed memory bus and a method for allowing I/O devices to be placed on both a conventional bus and the separate high speed bus.

Fastener

A fastener for fastening an elongate object to a support structure, the fastener comprising a body portion formed entirely of one or more electrically non-conductive materials and comprising a bridge, a first column extending substantially perpendicularly from a first end of the bridge and a second column extending substantially perpendicularly from a second end of the bridge, the bridge and columns together forming a U-shaped receptacle for engaging the elongate object, and a nail formed entirely of one or more electrically non-conductive materials and partially contained within the first column of the body portion for positively engaging with the support structure upon the application of force by a driving mechanism thereby fastening the elongate object to the support structure.

Medical port for an emergency safety resuscitator

A medical port for an emergency safety resuscitator having a collapsible bag with an outlet. An adapter has a first end available for attachment to, and communication with, the outlet of the collapsible bag. A second end of the adapter attaches to a first aperture of a tube having three apertures. The second aperture of the tube is releasably covered by a self-sealing membrane. And the third aperture of the tube is available for connection either to a mask or an endotracheal tube.

System and method for retrieving registry data

Retrieving information form from the registry include by creating a registry interface database containing information regarding registry data and uniquely identifying every registry entry for a registry interface. Source header files are generated using information about a program module, such as an application, contained in the registry interface database. The source header files are compiled with the application to generate the application's executable file. During run-time of the application, the registry interface is called by the application to retrieve registry data. If available, the registry interface retrieves the registry data and forwards this information to the application. In the event that the registry data is not available, the registry interface retrieves a default value in place of the registry data and forwards that default data to the application. A policy may be implemented by checking a policy area of the registry for the registry data and invoking the policy.

Methods and systems for providing personalized, real-time information based on remotely retrieved information

This disclosure relates generally to systems and methods for providing personalized financing information and, more particularly, systems and methods for providing personalized financing information via a dealership website using an API associated with a financial service provider. In one embodiment, a system includes memory hardware storing instructions that configure processing hardware to receive a loan request for a buyer via a real-time API that includes at least buyer identification and financial information and information associated at least one inventory item presented on a dealership website. The system may also determine financing information comprising prospective financing terms for the at least one item based on at least the loan request. The server may also provide, to the dealership server via the real-time API, the determined financing information for presentation on the dealership website, including prospective financing terms information corresponding to each of the at ...

SYSTEMS AND METHODS FOR EXPORTING AUTO FINANCE INFORMATION

This disclosure relates generally to systems and methods for providing personalized financing information and, more particularly, systems and methods for providing personalized financing information via a dealership website using an API associated with a financial service provider. In one embodiment, a system includes memory hardware storing instructions that configure processing hardware to receive a loan request for a buyer via a real-time API that includes at least buyer identification and financial information and information associated at least one inventory item presented on a dealership website. The system may also determine financing information comprising prospective financing terms for the at least one item based on at least the loan request. The server may also provide, to the dealership server via the real-time API, the determined financing information for presentation on the dealership website, including prospective financing terms information corresponding to each of the at least one item. 1. A financial service system for providing personalized financing information for incorporation into a dealership website via an API , comprising:memory hardware storing instructions; and receive, from a dealership server via a real-time API configured to provide financing information determinations, a loan request for a buyer that includes at least buyer identification information, buyer financial information, and information associated with at least one item contained within an inventory listing presented on a dealership website associated with the dealership server;', 'determine financing information comprising prospective financing terms for the at least one item based on at least the loan request; and', 'provide, to the dealership server via the real-time API, the determined financing information for presentation on the dealership website, wherein the determined financing information comprises prospective financing terms information corresponding to each of the ...

Combination transaction card and informative book

Combination transaction card and a credit card sized informative book with a multi page credit card sized book and a plastic coated top cover panel, the book consisting of a plurality of pages, and the plastic cover panel acting as a transaction card incorporating specific owner information such as a one of a kind number, a magnetic strip, bar code or an embedded micro-chip for the purpose of consumer purchasing transactions.

Cooler support shelf

The cooler support shelf is a rectangular platform having each of two corner sections of one side of the platform perpendicularly connected to separate vertical rails. The tops of the two rails are curved into hooks in the direction away from the platform. Diagonal support struts are connected from opposed sides of the platform to the lower part of each vertical rail. A hook and loop restraining strap is connected near the top of each vertical rail. The two straps can connect around the cooler to keep it in place on the platform.

Device for Refilling a Fuel Cartridge for a Fuel Cell

A refillable fuel supply assembly for a fuel cell is disclosed herein. The assembly includes a refillable fuel supply adapted to supply fuel to a fuel cell, a refilling fuel cartridge containing fuel to be transferred to the refillable fuel supply, and a lock-and-release device connecting the refilling fuel cartridge to the refillable fuel supply to transport fuel from the refilling fuel cartridge to the refillable fuel supply. The lock-and-release device also retains the refilling fuel cartridge to the refillable fuel supply until the refilling fuel cartridge is substantially free of fuel.

Authentication and pairing of devices using a machine readable code

An MR code is generated within a browser on a client device and is read by a mobile application on a mobile device. A communication channel is then established through a web-based service, between the browser and the mobile application on the mobile device. The mobile application generates a user interface display on the mobile device that allows user selection of content. The mobile application sends a link to that content to the browser, which accesses and renders the content on the client device. User input commands to control the rendered content are also received at the mobile device and sent to the browser through the communication channel.

Balanced bi-directional current source

A balanced bi-directional current source is provided, which includes first and second current output terminals, a current control circuit, first and second amplifiers and first and second sense impedances. The current control circuit has a reference input, a feedback input, and a control output, which is based on the reference input and the feedback input. The first amplifier has a first amplifier input, which is coupled to the control output, and a first amplified output. The second amplifier has a second amplifier input, which is coupled to the control output, and a second amplified output, which is inverted relative to the first amplified output. The first sense impedance is coupled in series between the first amplified output and the first current output terminal and has a feedback output which is coupled to the feedback input. The second sense impedance is matched with the first impedance and is coupled in series between the second amplified output and the second current output terminal ...

Determining media size by monitoring usage

Devices and methods to determine media size in a printing device. Media being added to a media sheet tray of a printing device is detected. A size of the media in the tray is estimated based only on at least one of: a size of the media in the tray prior to the media being added, a size of the media recently used prior to the media being added, and a size of the media most frequently used. A selection of previously used sizes of media is displayed on a user interface. The selection comprises: the size of the media in the tray prior to the media being added, the size of the media recently used prior to the media being added, and the size of the media most frequently used. Confirmation of the size of the media added to the tray is received, on the user interface.

Gaming systems and methods

The invention relates generally to methods and apparatus for playing games involving numbers or symbols, including but not limited to the classic game of BINGO. More particularly, the methods and apparatus relate to games involving matrices or arrays of numbers or symbols and different techniques and/or equipment used when playing the games, which help define how the games are won.

System and method for creation, distribution, and utilization of portable knowledge format

The present invention relates to systems and methods for facilitating the distribution of content in an accessible data structure. The method of the present invention comprises selecting one or more items of content from one or more content sources. Metadata associated with the one or more items of content is retrieved. Additionally, an index is constructed corresponding to the one or more items of content. The one or more items of content, associated metadata and index are stored in an accessible data structure according to a hierarchy. The accessible data structure is distributed and the contents of the accessible data structure are displayed.

Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives

The present invention provides methods and compositions for preparing 4-substituted 3-hydroxybutyric acid derivatives by halohydrin dehalogenase-catalyzed conversion of 4-halo-3-hydroxybutyric acid derivatives. The present invention further provides methods and compositions for preparing 4-halo-3-hydroxybutyric acid derivatives by ketoreductase-catalyzed conversion of 4-halo-3-ketobutyric acid derivatives The present invention also provides methods and compositions for preparing vicinal cyano, hydroxyl substituted carboxylic acid esters.

Authentication and pairing of devices using a machine readable code

An MR code is generated within a browser on a client device and is read by a mobile application on a mobile device. A communication channel is then established through a web-based service, between the browser and the mobile application on the mobile device. The mobile application generates a user interface display on the mobile device that allows user selection of content. The mobile application sends a link to that content to the browser, which accesses and renders the content on the client device. User input commands to control the rendered content are also received at the mobile device and sent to the browser through the communication channel.

Method and apparatus for tinnitus evaluation

Methods, articles of manufacture, and systems for evaluating tinnitus are disclosed herein. According to various embodiments, a tinnitus evaluation system may include a tinnitus evaluation module configured to perform one or more tinnitus evaluation tests. A tinnitus evaluation test may comprise generating a first single-frequency sound based at least in part on a sound of a patient's tinnitus, and generating a narrow-band sound centered at the frequency of the first single-frequency sound. Tests include a hearing threshold test, a loudness match test, a pitch match test, a bandwidth match test, a minimum masking level test, and a residual inhibition test.

Systems and methods for exporting auto finance information

This disclosure relates generally to systems and methods for providing personalized financing information and, more particularly, systems and methods for providing personalized financing information via a dealership website using an API associated with a financial service provider. In one embodiment, a system includes memory hardware storing instructions that configure processing hardware to receive a loan request for a buyer via a real-time API that includes at least buyer identification and financial information and information associated at least one inventory item presented on a dealership website. The system may also determine financing information comprising prospective financing terms for the at least one item based on at least the loan request. The server may also provide, to the dealership server via the real-time API, the determined financing information for presentation on the dealership website, including prospective financing terms information corresponding to each of the at ...

Dynamic Federations

Systems and methods of establishing IP telephony sessions between enterprises are disclosed. A first enterprise requests an association with a second enterprise. Both enterprises and the second enterprise belong to the same federation. The association request is accepted, to establish an association between the first and second enterprises. In response to the acceptance, a direct routed path is established between the first enterprise and the second enterprise. One of the associated enterprises requests activation of an IP telephony service. If the request to activate references the association, an IP telephony session is established using the direct routed path.

Scanning probe microscope

A scanning probe microscope with a first actuator (3) configured to move a feature in the form of a tip (2) so that the feature follows a scanning motion. A vision system (10) is configured to collect light from a field of view to generate image data. The field of view includes the feature and the light from the field of view travels from the feature to the vision system via the steering element (13). A tracking control system (15)bis configured to generate one or more tracking drive signals in accordance with stored reference data. A second actuator (14) is configured to receive the one or more tracking drive signals and move the steering element on the basis of the one or more tracking drive signals so that the field of view follows a tracking motion which is synchronous with the scanning motion and the feature remains within the field of view. An image analysis system (20) is configured to analyse the image data from the vision system to identify the feature and measure an apparent motion ...

Systems and methods for the matching of materials data to parts data

Systems and methods for correlating materials records to part records. At least one materials record is provided with a corresponding digital materials images and a plurality of parts records are provided with at least one corresponding digital parts image. The materials records are automatically compared to the part records, and potential matches are identified. Any digital materials images and parts images for the potential matches are displayed to the user for confirmation of a match.

Efavirenz tablet formulation having unique biopharmaceutical characteristics

The present invention provides an efavirenz tablet formulation which, when administered as a single dose to a subject, provides a mean maximum plasma concentration (Cmax) of about 4 μM to about 14 μM, a mean time of maximum plasma concentration (Tmax) of about 2 hours to about 5 hours, and a mean area under the plasma concentration versus time curve from time zero to time infinity (AUC) of about 190 μM·hour to about 470 μM·hour.

RADIATION AND RADIOCHEMICALLY STERILIZED FIBER-REINFORCED, COMPOSITE URINOGENITAL STENTS

A radiation and radiochemically sterilized, multi-component, fiber-reinforced composite, absorbable/disintegratable urinogenital stent, such as an endoureteral stent, with radiomodulated residence time in the biological site of 1 to 10 weeks depending on the high energy radiation dose used for sterilization. 1. A multi-component disintegratable stent comprises:a tubular matrix having a body and at least one position retaining end;a central coil;a knitted mesh comprising an absorbable yarn; andwherein tubular matrix is reinforced with and impregnates the central coil and knitted mesh and the stent exhibits 1 to 10 week disintegration and strength retention profiles.2. A multi-component disintegratable stent as set forth in claim 1 , wherein the central coil is radiopaque and includes radiopaque microparticles.3. A multi-component disintegratable stent as set forth in wherein the at least one position-retaining end comprises a flexible extension of the body claim 1 , and has a loop shape with an open end parallel to an axis of the body after insertion wherein the loop can be made co-linear with the aid of an applicator.4. A multi-component disintegratable stent as set forth in wherein the matrix comprises an absorbable claim 1 , high molecular weight claim 1 , low-crystallinity claim 1 , segmented polyaxial copolyester exhibiting an inherent viscosity of from about 0.5 to about 2.0 dL/g and heat of fusion (ΔHf) of from about 2 to about 30 J/g and derived from 1-lactide and at least one additional monomer selected from the group consisting of glycolide claim 1 , trimethylene carbonate claim 1 , ε-caprolactone claim 1 , p-dioxanone claim 1 , 1 claim 1 ,5-dioxepan-2-one and a morpholinedione.5. A multi-component disintegratable stent as set forth in wherein the matrix comprises an absorbable claim 1 , segmented claim 1 , polyaxial copolyester and a high molecular weight claim 1 , hydrophilic polymeric additive having a molecular weight of about 1 to about 70 kDa claim 1 ...

Log Chipper with Log Jam Clearing Feature

A wood chipper includes an in-feed spout with an input end and an opposing feeding end, a motor-turned chipper blade to receive logs at the feeding end, and one or a pair of independently-operable, hydraulic arms movable between a first position external to the in-feed spout and a second position internal to the in-feed spout through a gap in the in-feed spout. When inserted, the arms clear jammed logs laying anywhere across the width of the in-feed spout. The arms are operated by hydraulic rams secured to a bracket, preferably attached to a cover over a portion of the in-feed spout near the chipper blade and in proximity to the gap in the in-feed spout. 1. A wood chipper , comprising:(a) an in-feed spout having a floor, a first side, an opposing second side, a width defined by said first side and said second side, an input end and an opposing feeding end, said in-feed spout having a major dimension running from said input end to said feeding end, said floor having a gap formed in said in-feed spout across said width of said in-feed spout;(b) a chipper blade positioned to receive logs at said feeding end of said in-feed spout;(c) a motor in operational connection with said chipper blade to rotate said chipper blade;(d) an arm system having a first position external to said in-feed spout and proximate to said gap, and a second position inserted into said in-feed spout, said arm system crossing through said gap and across said width of said in-feed spout when moving from said first position to said second position and, when logs are on said in-feed spout, said arm system lifting said logs from said floor; and(e) a ram system in operating connection with said arm system, said ram system moving said arm system from said first position to said second position.2. The wood chipper as recited in claim 1 , wherein said arm system further comprises a first arm and an opposing second arm claim 1 , said first arm being positioned on said first side of said in-feed spout and ...

Absorbable crystalline copolyester-based bioactive hydroforming luminal liner compositions

Bioactive, hydroforming luminal liner compositions are formed of high molecular weight crystalline, absorbable copolyesters dissolved in a liquid derivative of a polyether glycol that undergoes transformation into a tissue-adhering, resilient interior cover or liner for the controlled release of its bioactive payload at clinically compromised conduits in humans as in the case of bacteria- and yeast-infected vaginal canals, esophagi, and arteries following angioplasty.

Extendable Self-Supporting Material Composites and Manufacture Thereof

Specific composite materials described herein are based on the discovery that certain selections of materials and manufacturing conditions and processes provide unexpectedly improved self-supporting thin-film composite materials. It has been discovered that certain combinations of backing materials, shrink film materials, and manufacturing conditions provide improved composites having highly controllable, readily repeatable, and stable arc shaped cross-web curled structures. In general, the composite materials described herein comprise a dimensionally alterable film such as a polyester shrink film having a first surface and a second surface, and a polyester backing material having a first surface and a second surface, wherein the second surface of the backing material is laminated to the first surface of the dimensionally alterable film. Upon activation of the alterable film, for example upon exposing the composite material comprising the polyester heat shrink film to heat, the composite material can be imparted with an arc shaped cross-web curled structure along it longitudinal width, resulting in resistance to bending in its axial length, and a self-supporting material. 1. A self-supporting composite having an axial length and a longitudinal width , the composite comprising:a polyester film backing having a first surface and a second surface;a heat activated polyester shrink film comprising a first surface and a second surface;a laminating adhesive disposed between the second surface of the backing and the first surface of the shrink film;the shrink film being oriented within the composite wherein, upon activation, the shrink film contracts greater along the longitudinal width of the composite than the axial length; andthe axial length of the composite has a curvature about the longitudinal width of the composite material induced by heat activation of the shrink film, wherein the curvature is in the shape of an arc and which curvature imparts stiffness to the ...

System and Methods for Generating Price Sensitivity

The present invention relates to systems and methods for calculating a segment's sensitivity to price changes. A histogram distribution is generated for transaction frequency by price as the initial part of the sensitivity analysis. The shape of this histogram may be used to extrapolate a sensitivity measure. This can be done in two distinct ways: statistical regression or slope approximation. For statistical regression, the inverse of the cumulative distribution function is first calculated. The slope of this function is determined to be the sensitivity; the steeper the curve the more sensitive the segment is to price changes. The second technique approximates the slope of the right hand side of the histogram in order to determine sensitivity. 1. A method for generating segment price sensitivity , useful in association with an integrated price management system , the method comprising:generating a histogram distribution of frequency of deals by deal price for a segment; andcalculating the sensitivity of the segment to price change using the shape of the histogram distribution.2. The method as recited in claim 1 , further comprising generating a segment from transaction logs.3. The method as recited in claim 2 , wherein the segment is generated using product attribute information claim 2 , market data claim 2 , and transaction history data.4. The method as recited in claim 1 , further comprising outputting the sensitivity to a pricing system.5. The method as recited in claim 4 , wherein the sensitivity is used by the pricing system as a pricing power factor in a risk/power analysis.6. The method as recited in claim 1 , wherein the sensitivity is calculated by computing an inverse cumulative distribution function of the histogram claim 1 , and determining the slope of the inverse cumulative distribution function.7. The method as recited in claim 1 , wherein the sensitivity is calculated by computing an approximation of a slope for the right hand curve of the ...

OIL BODY EXTRACTION AND USES

The present invention provides a method of extracting naturally occurring oil bodies comprising obtaining material containing naturally occurring oil bodies, recovering the oil bodies in a wet preparation and drying the oil bodies; and dried oil bodies obtained by the method and uses thereof. 1. A method of extracting naturally occurring oil bodies comprising:(i) obtaining material containing naturally occurring oil bodies;(ii) recovering the oil bodies in a wet preparation;(iii) drying the oil bodies.2. The method of wherein the dried oil bodies have a water activity of less than 0.3.3Euglena.. The method of wherein the material containing the naturally occurring oil bodies is selected from one or more of seeds claim 1 , pollen claim 1 , flowers claim 1 , roots and stems of flowering plants claim 1 , the spores and vegetative organs of non-flowering plants claim 1 , algae claim 1 , microalgae claim 1 , animal cells claim 1 , fungi and protists such as4echium. The method of wherein the seeds are seeds or kernels from one or more of the following plants claim 3 , sunflower claim 3 , soybean claim 3 , oil palm claim 3 , safflower claim 3 , almond claim 3 , macadamia claim 3 , cotton seed claim 3 , ground nut claim 3 , coconut claim 3 , oil seed rape claim 3 , claim 3 , borage claim 3 , linseed/flax/hemp claim 3 , evening primrose claim 3 , rice claim 3 , wheat claim 3 , oat claim 3 , maize and barley.5. The method of wherein the oil bodies contain triacylglycerol molecules enriched in unsaturated fatty acids6. The method of wherein the oil bodies contain omega-3 or other essential fatty acids7. The method of wherein the oil bodies are spray dried.8. The method of wherein before drying the oil bodies a carrier is added to the wet preparation.9. The method of wherein the carrier is a protein or a sugar.10. The method of wherein the carrier is maltodextrin.11. The method of wherein the dried oil bodies are in a powder form.12. The method of wherein the dried oil bodies ...

Extendable Self-Supporting Material Composites and Manufacture Thereof

Specific composite materials described herein are based on the discovery that certain selections of materials and manufacturing conditions and processes provide unexpectedly improved self-supporting thin-film composite materials. It has been discovered that certain combinations of backing materials, shrink film materials, and manufacturing conditions provide improved composites having highly controllable, readily repeatable, and stable arc shaped cross-web curled structures. In general, the composite materials described herein comprise a dimensionally alterable film such as a polyester shrink film having a first surface and a second surface, and a polyester backing material having a first surface and a second surface, wherein the second surface of the backing material is laminated to the first surface of the dimensionally alterable film. Upon activation of the alterable film, for example upon exposing the composite material comprising the polyester heat shrink film to heat, the composite material can be imparted with an arc shaped cross-web curled structure along it longitudinal width, resulting in resistance to bending in its axial length, and a self-supporting material. 1. A method of reducing deformation of an article during webbing process manufacturing , comprising:attaching a stabilizing layer to the article such that the stabilizing layer provides stabilization against deformation caused by the webbing process, wherein the stabilizing lawyer comprises a self-supporting composite having an axial length and a longitudinal width, the composite comprising:a backing having a first surface and a second surface;a heat activated shrink film comprising a first surface and a second surface;an adhesive disposed between the second surface of the backing and the first surface of the shrink film;the shrink film being oriented within the composite wherein, upon activation, the shrink film contracts greater along the longitudinal width of the composite than the axial length; ...

Heteroaromatic compounds and their use as dopamine d1 ligands

The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D1-mediated (or D1-associated) disorders including, e.g., schizophrenia (e.g., its cognitive and negative symptoms), cognitive impairment (e.g., cognitive impairment associated with schizophrenia, AD, PD, or pharmacotherapy therapy), and Parkinson's disease.

HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS

The present invention provides, in part, compounds of Formula I: 2. The compound of claim 1 , or a pharmaceutically acceptable salt thereof claim 1 , wherein Lis O or S.34-. (canceled)6. The compound of claim 5 , or a pharmaceutically acceptable salt thereof claim 5 , wherein:{'sup': 9', '9', '9, 'sub': 1-4', '1-4', '3-4', '1-4', '1-4', '1-4', '3-4', '1-4', '1-4', '1-4', '1-4', '1-4', '1-4, 'each Ris independently selected from the group consisting of —CN, Calkyl, Chaloalkyl, Ccycloalkyl, cyclopropylmethyl, and cyclobutylmethyl, wherein the Calkyl of Ris optionally substituted with one or more substituents each independently selected from the group consisting of halogen, —OH, —CN, Calkoxy, and Chaloalkoxy; and wherein each of the Ccycloalkyl, cyclopropylmethyl, and cyclobutylmethyl of Ris optionally substituted with one or more substituents each independently selected from the group consisting of halogen, —OH, —CN, Calkyl, Chaloalkyl, Chydroxylalkyl, Ccyanoalkyl, Calkoxy, and Chaloalkoxy; and'}{'sup': 9A', '5', '6', '5', '6', '8', '8', '14', '14', '14', '14', '15', '14', '15, 'sub': 1-3', '1-3', '2', '2', '2', '2', '2', '2', '2', '2, 'Ris selected from the group consisting of H, Calkyl, Chydroxylalkyl, allyl, —S(═O)N(R)(R), —C(═O)N(R)(R), —C(═O)—R, —C(═O)—OR, —C(R)—OH, —C(R)—OS(═O)H, —C(R)—OP(═O)(OH), —C(R)—OR, and —C(R)—OC(═O)—R.'}7. (canceled)8. The compound of claim 6 , or a pharmaceutically acceptable salt thereof claim 6 , wherein each Ris independently methyl or ethyl.10. The compound of claim 9 , or a pharmaceutically acceptable salt thereof claim 9 , wherein:{'sup': 10', '10', '10, 'sub': 1-4', '3-4', '1-4', '1-4', '1-4', '3-4', '1-4', '1-4', '1-4', '1-4', '1-4', '1-4, 'Ris selected from the group consisting of —CN, Calkyl, Ccycloalkyl, cyclopropylmethyl, and cyclobutylmethyl, wherein the Calkyl of Ris optionally substituted with one or more substituents each independently selected from the group consisting of halogen, —OH, —CN, Calkoxy, and Chaloalkoxy; and ...

User-Management of Third-Party User Information

Systems and methods for generating and broadcasting a dynamic identifier are presented. Based on the current context and rules established for accessing personal information, a dynamic identifier corresponding to a computer user is dynamically generated and provided to a computing device corresponding to the computer user. The computing device may broadcast the dynamic identifier to others. Upon receipt of a dynamic identifier, a party wishing to determine information regarding the broadcasting party must query an information service with the dynamic identifier. According to a set of rules and/or permissions established for the target computer user (broadcasting the dynamic identifier), accessible information is identified and returned to the requesting party. Additionally, a user is provided with the ability to edit, add to, and/or delete information that is stored by the identification service regarding the user on behalf of a submitting party. 1. A computer-implemented method as implemented by an identification service for managing user information regarding a user , the method comprising:maintaining a data store that stores user information regarding a plurality of computer users on behalf of submitting parties;receiving user information corresponding to a user of the plurality of users from a submitting party, wherein the user information is received in conjunction with a current dynamic user identifier associated with the user;receiving an instruction to present the user information to the user;providing the user information to the user;receiving modified user information from the user, wherein the modified user information comprises the user information provided to the user as modified by the user; andstoring the modified user information in the data store in association with the user.2. The computer-implemented method of claim 1 , wherein the instruction to present the user information to the user is automatically generated at the identification service upon ...

AUTOMATED MEETING SCHEDULER

A receiver receives a request to schedule a meeting from a user and in response, prompts the user to provide meeting information including time information and attendee information for scheduling the meeting. A meeting scheduler identifies potential dates and potential times based on the meeting information. The meeting scheduler further detects locations of the attendees based on the potential dates and identifies potential meeting locations based on attendees' location. The meeting scheduler also computes date scores for the potential dates, time scores for the potential times, and location scores for the meeting locations to select a date, a time, and a meeting location based on scores to determine a meeting schedule. The meeting scheduler further selects a conferencing mechanism for the meeting and provides the meeting schedule comprising the selected date, time, and meeting location, and the selected conferencing mechanism as a meeting invite option to the user. 1. A system comprising: receive an input from a user, wherein the input is indicative of a request to schedule a meeting; and', 'in response to receiving the input, prompt the user to provide meeting information including time information and attendee information for scheduling the meeting; and, 'a receiver to a time identifier to identify one or more potential dates for scheduling the meeting based on the meeting information, wherein a potential date has one or more potential times for scheduling the meeting;', determine availability of the attendees based on the potential dates for scheduling the meeting;', 'detect locations of the attendees based on the availability of the attendees, the potential dates, and a location group tree, wherein the location group tree is a recursive data structure;', 'identify one or more potential meeting locations based on the locations of the attendees; and', 'determine availability of the meeting locations based on the potential dates for scheduling the meeting; and, ' ...

Active apparel and fabric and coverings

A fabric delivers active ingredients to a surface when the fabric includes a moist-vapor porous combination of fabric materials, and the fabric comprises at least 0.5% by total weight of at least one layer of the fabric of a superabsorbent polymer fiber. The superabsorbent polymer fiber contains an absorbed aqueous reservoir of an aqueous solution carrying the active ingredients. The superabsorbent fiber has a coating on its surface of an aqueous penetrable layer through which a liquid in the absorbed aqueous reservoir can migrate or flow, carrying the active ingredients onto an exposed surface of the superabsorbent polymer fiber, so that the active ingredients on the surface of the superabsorbent polymer can react or interact with an environment in contact with the active ingredients on the superabsorbent polymer fiber surface.

Contraceptive and related device

An intravaginal ring for the controlled release of at least one bioactive agent may further contain at least one of a non-bioabsorbable microparticulate ion-exchanging polymer, a fully bioabsorbable polymeric matrix, a biostable hydrophilic elastomeric polymeric matrix, a biostable amphiphilic elastomeric polymeric matrix, a biostable elastomeric polymeric matrix containing an inorganic microparticulate, and a biostable elastomeric porous polymeric matrix, each to aid in the release and/or modulate the release of the bioactive agent.

Synthetic mechanical hemostatic composition, method of making and use thereof

A biocompatible, polymeric composition is disclosed. The composition comprises a base polymer comprising (i) a prepolymer comprising para-dioxanone (PDO) and trimethylene carbonate (TMC); and (ii) an end-graft polymer chain comprising a polylactone. Also disclosed are a method for treating bleeding from bone or bony structures using the composition, a method for filling a void or correct a defect in a bone using the composition, and a method for producing the biocompatible, polymeric composition of the present application.

PERSONAL INDEPENDENT MOBILITY AND LIFT DEVICE

A mobility device with sit and stand assist for providing disabled individuals with the ability to rise from a sitting position and move about without the aid of an assistant. The mobility device with sit and stand assist generally includes a motorized and steerable Drive Carriage Assembly, a Trailing Cart Assembly attached to the Drive Carriage Assembly, an Outrigger Assembly attached to the Trailing Cart Assembly, a Lift Arm Assembly attached to the Outrigger Assembly, a Lift Arm Locking Bolt Assembly attached to the Lift Arm Assembly, a Knee Brace Assembly attached to the Trailing Cart Assembly, a Control Assembly attached to the Lift Arm Assembly, and a User Connection Group comprised of various components designed to enable the user to comfortably connect himself/herself to the Device such that the user might be able to utilize and benefit from the Device. 2. The lift device of claim 1 , wherein said base comprises:a drive carriage assembly;a trailing cart assembly pivotably connected to said drive carriage assembly; andone or more wheels attached to the bottom of said base.3. The lift device of claim 1 , wherein said base is motorized.4. The lift device of claim 2 , wherein said drive carriage assembly is removable from said base.5. The lift device of claim 2 , wherein said trailing cart assembly is pivotably connected to said drive carriage assembly by a connecting pin.6. The lift device of claim 2 , wherein said trailing cart assembly comprises a steering limiter.7. The lift device of claim 1 , wherein said outrigger assembly stabilizes said lift device without increasing a counterbalance weight.8. The lift device of claim 1 , further comprising a fulcrum claim 1 , wherein said one or more lift arms and said outrigger assembly utilize said fulcrum.9. The lift device of claim 1 , wherein said outrigger assembly can be lowered into contact with any weight-supporting surface.10. The lift device of claim 1 , wherein said outrigger assembly comprises outrigger ...

Bottle Cap Opener And Launcher

A bottle cap opener and launcher for opening bottles and then launching the caps for entertainment. The bottle cap opener and launcher generally includes a body that holds a collar and a pry tooth, wherein the collar can be pressed to cause the pry tooth to extend outwardly from the body. When not in use, the pry tooth retracts into the body, urged by an internal compression spring. In the extended position the pry tooth can be used to pry caps off of bottles. The body also serves as a lever to allow the user to operate the opener. 1. A bottle opener , comprising:a pry tooth having a shaft, a pry end, and a second end;a body having a first surface and a collar cavity within the body, the collar cavity having an inner surface defined by a shelf between the collar cavity and the first surface, wherein the pry tooth shaft extends into the collar cavity through an opening in the shelf;a collar movably positioned in the collar cavity, the collar having a coupling end coupled to the pry tooth shaft at the second end; anda compression spring within the collar cavity, positioned over the shaft between the shelf and the coupling end of the collar;wherein the pry tooth and the collar are movable between a retracted position and an extended position.2. The bottle opener of claim 1 , wherein the opening and the collar cavity are cylindrical.3. The bottle opener of claim 2 , wherein the opening and the collar cavity are coaxial to each other.4. The bottle opener of claim 3 , wherein an inner surface of the pry end contacts the first surface when the pry tooth is in the retracted position.5. The bottle opener of claim 1 , wherein the body further comprises a pry tooth recess in the first surface claim 1 , and wherein an inner surface of the pry tooth recess defines a surface of the shelf.6. The bottle opener of claim 5 , wherein the pry end of the pry tooth is shaped to substantially fill the pry tooth recess when the pry tooth is in the retracted position.7. The bottle opener of ...

Bottle Cap Opener And Launcher

A bottle cap launcher for launching bottle caps for entertainment. The bottle cap launcher generally includes a body, a collar, and a pry tooth with a shaft mounted in the collar. The launcher also has a spring compressed between the collar and the body, the spring surrounding the pry tooth shaft. The body can slide on the shaft of the pry tooth. Bottle caps can be leveraged under the pry tooth and positioned to compress the spring and displace the body toward the collar. When released, the bottle cap is launched by the body when the spring forces it back to its original, relaxed position on the pry tooth shaft. 1. A bottle cap launcher , comprising:a pry tooth having a shaft, a pry end, and a second end;a body having a first surface and a shaft opening, wherein the pry tooth shaft extends through the shaft opening and wherein the body is slidable on the pry tooth shaft;a collar having a coupling end coupled to the pry tooth shaft at the second end; anda compression spring positioned between the collar and the body, such that the compression spring urges the body toward the pry end;wherein the body is movable between a relaxed position and an compressed position on the pry tooth shaft.2. The bottle cap launcher of claim 1 , wherein the body comprises a flange extending beyond the first surface.3. The bottle cap launcher of claim 2 , wherein the shaft opening has a circular cross section.4. The bottle cap launcher of claim 1 , wherein the shaft opening has a circular cross section.5. The bottle cap launcher of claim 1 , wherein an inner surface of the pry end contacts the first surface when the pry tooth is in the relaxed position.6. The bottle cap launcher of claim 5 , wherein the pry tooth shaft is cylindrical.7. The bottle cap launcher of claim 6 , wherein the shaft opening has a circular cross section.8. The bottle cap launcher of claim 5 , wherein the shaft opening has a circular cross section.9. The bottle cap launcher of claim 1 , wherein the collar is ...

METHOD AND SYSTEM FOR MEASURING TORQUE AND TORSIONAL VIBRATION OF A ROTATING BODY

The present disclosure relates to a method and system for characterization of torque and torsional vibration in rotating bodies. More specifically, the present disclosure describes high-fidelity, high-speed characterization of the rotary motion of a body without the requirement for surface modification. The method and system rely on the inherent properties of the surface of the rotating body to determine the degree to which the rotating body vibrates, twists, or is otherwise translated. 1. A method for detecting a change in a rotating body comprising:providing a master pattern associated with surface topology of a body;rotating the body about an axis;during the rotating, measuring by way of a non-contact measuring technique at least one second pattern associated with surface topology of the body;comparing the at least one second pattern to the master pattern to determine any difference in surface topology of the body as a result of the rotating; anddetermining a change in the rotating body from the difference.2. The method of claim 1 , wherein only a single measurement point on the body is used to determine rotation speed.3. The method of claim 1 , wherein a single measurement point on the body is used to determine amplitude of angular vibration of the body.4. The method of claim 1 , wherein a single measurement point on the body is used to determine frequency of angular vibration of the body.5. The method of claim 1 , wherein multiple measurement points on the body are used to determine twist of the body.6. The method of claim 1 , wherein multiple measurement points on the body are used to determine twist of the body in order to calculate torque applied to the body.7. The method of claim 1 , wherein multiple measurement points on the body are used to determine motion on the body that is coherent between multiple measurement points in order to mitigate effects of vibration of the body that is not angular.8. The method of claim 1 , wherein multiple measurement points ...

HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS

The present invention provides, in part, compounds of Formula (I): and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D1-mediated (or D1-associated) disorders including, e.g., schizophrenia (e.g., its cognitive and negative symptoms), schizotypal personality disorder, cognitive impairment (e.g., cognitive impairment associated with schizophrenia, AD, PD, or pharmacotherapy therapy), ADHD, Parkinson's disease, anxiety, and depression. 2. (canceled)6. The compound of or a pharmaceutically acceptable salt thereof claim 5 , wherein Lis O or S.7. The compound of or a pharmaceutically acceptable salt thereof claim 5 , wherein Lis O.8. The compound of or a pharmaceutically acceptable salt thereof claim 5 , wherein each of T claim 5 , T claim 5 , T claim 5 , and Tis independently selected from the group consisting of H claim 5 , F claim 5 , Cl claim 5 , Br claim 5 , —CN claim 5 , methoxy claim 5 , Cfluoroalkoxy claim 5 , methyl claim 5 , and Cfluoroalkyl.9. The compound of or a pharmaceutically acceptable salt thereof claim 5 , wherein:{'sup': 2', '2, 'Xis CT;'}{'sup': 3', '3, 'Xis CT; and'}{'sup': '5', 'Tis H.'}11. The compound of or a pharmaceutically acceptable salt thereof claim 10 , wherein each of Rand Ris independently H or halogen; and each of Rand Ris independently H claim 10 , halogen claim 10 , —CN claim 10 , methyl claim 10 , Chaloalkyl claim 10 , methoxy claim 10 , or Chaloalkoxy.12. The compound of or a pharmaceutically acceptable salt thereof claim 5 , wherein each of Rand Ris H; Ris H; and Ris H claim 5 , halogen claim 5 , —CN claim 5 , methyl claim 5 , or Chaloalkyl.14. The compound of or a pharmaceutically acceptable salt thereof claim 13 , wherein Moiety Mis selected from the group consisting of quinolinyl claim 13 , isoquinolinyl claim 13 , 1H-imidazo[4 claim 13 ,5-c]pyridinyl claim 13 , imidazo[1 claim ...

HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS

The present invention provides, in part, compounds of Formula (I) and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D1-mediated (or D1-associated) disorders including, e.g., schizophrenia (e.g., its cognitive and negative symptoms), schizotypal personality disorder, cognitive impairment (e.g., cognitive impairment associated with schizophrenia, AD, PD, or pharmacotherapy therapy), ADHD, Parkinson's disease, anxiety, and depression. 2. (canceled)6. The compound of or a pharmaceutically acceptable salt thereof claim 5 , wherein Lis O.7. The compound of or a pharmaceutically acceptable salt thereof claim 5 , wherein each of T claim 5 , T claim 5 , and Tis independently selected from the group consisting of H claim 5 , halogen claim 5 , —CN claim 5 , methoxy claim 5 , Cfluoroalkoxy claim 5 , methyl claim 5 , and Cfluoroalkyl claim 5 ,8. The compound of or a pharmaceutically acceptable salt thereof claim 5 , wherein Tis H and Tis H.10. The compound of or a pharmaceutically acceptable salt thereof claim 5 , wherein the compound of Formula I or a pharmaceutically acceptable salt thereof is a compound of Formula I-a or a pharmaceutically acceptable salt thereof.11. The compound of or a pharmaceutically acceptable salt thereof claim 5 , wherein each of Rand Ris independently H or halogen; and each of Rand Ris independently H claim 5 , halogen claim 5 , —CN claim 5 , methyl claim 5 , Chaloalkyl claim 5 , methoxy claim 5 , or Chaloalkoxy.12. The compound of or a pharmaceutically acceptable salt thereof claim 5 , wherein each of Rand Ris H; Ris H; and Ris H claim 5 , halogen claim 5 , —CN claim 5 , methyl claim 5 , or Chaloalkyl.14. The compound of or a pharmaceutically acceptable salt thereof claim 13 , wherein Moiety Mis selected from the group consisting of quinolinyl claim 13 , isoquinolinyl claim 13 , 1H-imidazo[4 claim ...

HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS

The present invention provides, in part, compounds of Formula I: 2. The method of wherein Lis O or S.4. The method of wherein:{'sup': 10', '10', '10, 'sub': 1-4', '3-4', '1-4', '1-4', '1-4', '3-4', '1-4', '1-4', '1-4', '1-4', '1-4, 'Ris selected from the group consisting of —CN, Calkyl, Ccycloalkyl, cyclopropylmethyl, and cyclobutylmethyl, wherein the Calkyl of Ris optionally substituted with 1, 2, 3, or 4 substituents each independently selected from the group consisting of halogen, —OH, —CN, Calkoxy, and Chaloalkoxy; and wherein each of the Ccycloalkyl, cyclopropylmethyl, and cyclobutylmethyl of Ris optionally substituted with 1, 2, 3, or 4 substituents each independently selected from the group consisting of halogen, —OH, —CN, Calkyl, Chaloalkyl, Chydroxylalkyl, Calkoxy, and Chaloalkoxy;'}{'sup': 10A', '5', '6', '5', '6', '8', '8', '14', '14', '14', '14', '15', '14', '15, 'sub': 1-3', '1-3', '2-4', '2', '2', '2', '2', '2', '2', '2', '2, 'Ris selected from the group consisting of H, Calkyl, Chydroxylalkyl, Calkenyl, —S(═O)N(R)(R), —C(═O)—N(R)(R), —C(═O)—R, —C(═O)—OR, —C(R)—OH, —C(R)—OS(═O)H, —C(R)—OP(═O)(OH), —C(R)—OR, and —C(R)—OC(═O)—R; and'}{'sup': 10B', '10B', '10B, 'sub': 1-4', '3-4', '1-4', '1-4', '1-4', '3-4', '1-4', '1-4', '1-4', '1-4', '1-4, 'Ris selected from the group consisting of Calkyl, Ccycloalkyl, cyclopropylmethyl, and cyclobutylmethyl, wherein the Calkyl of Ris optionally substituted with 1, 2, 3, or 4 substituents each independently selected from the group consisting of halogen, —OH, —CN, Calkoxy, and Chaloalkoxy; and wherein each of the Ccycloalkyl, cyclopropylmethyl, and cyclobutylmethyl of Ris optionally substituted with 1, 2, 3, or 4 substituents each independently selected from the group consisting of halogen, —OH, —CN, Calkyl, Chaloalkyl, Chydroxylalkyl, Calkoxy, and Chaloalkoxy.'}6. The method of wherein:{'sup': 11', '11', '11, 'sub': 1-4', '3-4', '1-4', '1-4', '1-4', '3-4', '1-4', '1-4', '1-4', '1-4', '1-4, 'each Ris independently ...

ADVANCED FABRIC TECHNOLOGY AND FILTERS

A filter material for entrapping particles and actively affecting the trapped particles within the filter. The fabric has a blend of hydrophilic superabsorbent fibers and non-superabsorbent hydrophilic fibers that is sufficiently porous as to allow gaseous flow through the fabric. The fabric having a thickness and the fabric has as a coating of a mixture of a chemically or physically active compound and a liquid carrier forming an active composition on both the outer surface of the hydrophilic superabsorbent fibers, and the hydrophilic superabsorbent fibers have a central volume also retaining the active composition. The central volume of the hydrophilic superabsorbent fibers acting as a reservoir for replacement of the active compound into the coating when concentration of active compounds in the coating are reduced to a concentration less than concentrations of the active compound within the central volume; and the liquid carrier is an aqueous liquid. 1. A filter material for entrapping particles and actively affecting the trapped particles within the filter comprising:a blend of hydrophilic superabsorbent fibers and non-superabsorbent hydrophilic fibers;the blend comprising a fabric that is sufficiently porous as to allow gaseous flow of more than 10 linear ft/min at a pressure of 0.5-inch of water (125 Pa) through the fabricthe fabric having a thickness and the fabric has as a coating of a mixture of an antimicrobially active compound and a liquid carrier forming an antimicrobial composition on both the outer surface of the hydrophilic superabsorbent fibers, and the hydrophilic superabsorbent fibers have a central volume also retaining the antimicrobial composition;the coating on the hydrophilic superabsorbent fibers are present within the thickness of the fabric and on the hydrophilic superabsorbent fibers throughout at least 25% of the thickness of the fabric;the central volume of the hydrophilic superabsorbent fibers acting as a reservoir for replacement of ...

HETEROCYCLIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS

The present invention provides, in part, compounds of Formula (I): and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D1-mediated (or D1-associated) disorders including, e.g., schizophrenia (e.g., its cognitive and negative symptoms), schizotypal personality disorder, cognitive impairment (e.g., cognitive impairment associated with schizophrenia, AD, PD, or pharmacotherapy therapy), ADHD, Parkinson's disease, anxiety, and depression. 2. (canceled)6. The compound of or a pharmaceutically acceptable salt thereof claim 5 , wherein Lis O or S.7. The compound of or a pharmaceutically acceptable salt thereof claim 5 , wherein Lis O.8. The compound of or a pharmaceutically acceptable salt thereof claim 5 , wherein each Tis independently selected from the group consisting of H claim 5 , halogen claim 5 , —CN claim 5 , methoxy claim 5 , Cfluoroalkoxy claim 5 , methyl claim 5 , and Cfluoroalkyl; and each Tis independently selected from the group consisting of H claim 5 , —OH claim 5 , halogen claim 5 , —CN claim 5 , methoxy claim 5 , Cfluoroalkoxy claim 5 , methyl claim 5 , and Cfluoroalkyl.9. The compound of or a pharmaceutically acceptable salt thereof claim 5 , wherein Tis H and Tis H.10. The compound of or a pharmaceutically acceptable salt wherein one of Tis H and the other is H or —OH.12. The compound of or a pharmaceutically acceptable salt thereof claim 11 , wherein the compound of Formula I or a pharmaceutically acceptable salt thereof is a compound of Formula I-a or a pharmaceutically acceptable salt thereof.13. The compound of or a pharmaceutically acceptable salt thereof claim 5 , wherein each of Rand Ris independently H or halogen; and each of Rand Ris independently H claim 5 , halogen claim 5 , —CN claim 5 , methyl claim 5 , Chaloalkyl claim 5 , methoxy claim 5 , or Chaloalkoxy.14. The compound of or a ...

HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS

The present invention provides, in part, compounds of Formula I: 2. The compound of claim 1 , or a pharmaceutically acceptable salt thereof claim 1 , wherein each of T claim 1 , T claim 1 , T claim 1 , and Tis independently selected from the group consisting of H claim 1 , F claim 1 , —CN claim 1 , methoxy claim 1 , Cfluoroalkoxy claim 1 , methyl claim 1 , and Cfluoroalkyl claim 1 ,3. The compound of claim 1 , or a pharmaceutically acceptable salt thereof claim 1 , wherein Tis H and Tis H.6. The compound of claim 1 , or a pharmaceutically acceptable salt thereof claim 1 , wherein:{'sup': '1', 'Xis N or CH;'}{'sup': 1', '2, 'sub': 1-4', '1-4', '1-4', '1-4', '3-4, 'each of Rand Ris independently selected from the group consisting of H, halogen, —CN, Calkyl, Chaloalkyl, Calkoxy, Chaloalkoxy, and Ccycloalkyl;'}{'sup': 3', '4', '5', '6', '8, 'sub': 1-4', '1-4', '1-4', '3-4, 'each of Rand Ris independently selected from the group consisting of H, halogen, —OH, —CN, Calkyl, Chaloalkyl, Chaloalkoxy, Ccycloalkyl, a 4- to 7-membered heterocycloalkyl, —N(R)(R), and —OR,'}{'sup': 5', '6, 'sub': 1-4', '1-4', '3-7, 'each of Rand Rindependently is H or selected from the group consisting of Calkyl, Chaloalkyl, and Ccycloalkyl;'}{'sup': 5', '6, 'sub': 1-4', '1-4', '3-6', '1-4', '1-4, 'or Rand Rtogether with the N atom to which they are attached form a 4- to 7-membered heterocycloalkyl or a 5-membered heteroaryl, each optionally substituted with 1, 2, or 3 substituents each independently selected from the group consisting of halogen, —CN, Calkyl, Calkoxy, Ccycloalkyl, Chaloalkyl, and Chaloalkoxy; and'}{'sup': '8', 'sub': 1-4', '3-6', '1-4', '1-4', '3-6', '1-4', '1-4, 'Ris selected from the group consisting of Calkyl, Ccycloalkyl, a 4- to 7-membered heterocycloalkyl, phenyl, and a 5- to 6-membered heteroaryl, each optionally substituted with 1, 2, or 3 substituents each independently selected from the group consisting of halogen, —CN, Calkyl, Chaloalkyl, Ccycloalkyl, Calkoxy, and ...

HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS

The present invention provides, in part, compounds of Formula I: 2. The compound of claim 1 , or a pharmaceutically acceptable salt thereof claim 1 , wherein Lis O or S.{'b': 3', '4, '-. (canceled)'}6. The compound of claim 5 , or a pharmaceutically acceptable salt thereof claim 5 , wherein:{'sup': 9', '9', '9, 'sub': 1-4', '1-4', '3-4', '1-4', '1-4', '1-4', '3-4', '1-4', '1-4', '1-4', '1-4', '1-4', '1-4, 'each Ris independently selected from the group consisting of —CN, Calkyl, Chaloalkyl, Ccycloalkyl, cyclopropylmethyl, and cyclobutylmethyl, wherein the Calkyl of Ris optionally substituted with one or more substituents each independently selected from the group consisting of halogen, —OH, —CN, Calkoxy, and Chaloalkoxy; and wherein each of the Ccycloalkyl, cyclopropylmethyl, and cyclobutylmethyl of Ris optionally substituted with one or more substituents each independently selected from the group consisting of halogen, —OH, —CN, Calkyl, Chaloalkyl, Chydroxylalkyl, Ccyanoalkyl, Calkoxy, and Chaloalkoxy; and'}{'sup': 9A', '5', '6', '5', '6', '8', '8', '14', '14', '14', '14', '15', '14', '15, 'sub': 1-3', '1-3', '2', '2', '2', '2', '2', '2', '2', '2, 'Ris selected from the group consisting of H, Calkyl, Chydroxylalkyl, allyl, —S(═O)N(R)(R), —C(═O)—N(R)(R), —C(═O)—R, —C(═O)—OR, —C(R)—OH, —C(R)—OS(═O)H, —C(R)—OP(═O)(OH), —C(R)—OR, and —C(R)—OC(═O)—R.'}7. (canceled)8. The compound of claim 6 , or a pharmaceutically acceptable salt thereof claim 6 , wherein each Ris independently methyl or ethyl.10. The compound of claim 9 , or a pharmaceutically acceptable salt thereof claim 9 , wherein:{'sup': 10', '10', '10, 'sub': 1-4', '3-4', '1-4', '1-4', '1-4', '3-4', '1-4', '1-4', '1-4', '1-4', '1-4', '1-4, 'Ris selected from the group consisting of —CN, Calkyl, Ccycloalkyl, cyclopropylmethyl, and cyclobutylmethyl, wherein the Calkyl of Ris optionally substituted with one or more substituents each independently selected from the group consisting of halogen, —OH, —CN, Calkoxy, and ...

Apparatus and method for prevention and mitigation of deep vein thrombosis

Apparatus and methodologies for the mitigation and prevention of venous thromboembolism-related disorders resulting from by venous blood stasis. More specifically, repeated cycles of brief bouts of intermittent electrical stimulation are repeated every several minutes to contract at least one target muscle, causing a temporary increase in venous blood flow and blood velocity in the veins in the region of the target muscle(s). The present intermittent electrical stimulation paradigm may be used to mimic physiological responses following voluntary contraction of the target muscle(s), without fatiguing the muscle(s).

HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS

The present invention provides, in part, compounds of Formula I: 2. The compound of or a pharmaceutically acceptable salt thereof claim 1 , wherein each of T claim 1 , T claim 1 , and Tis independently selected from the group consisting of H claim 1 , halogen claim 1 , —CN claim 1 , methoxy claim 1 , Cfluoroalkoxy claim 1 , methyl claim 1 , and Cfluoroalkyl claim 1 ,3. The compound of or a pharmaceutically acceptable salt thereof claim 1 , wherein Tis H and Tis H.4. The compound of or a pharmaceutically acceptable salt thereof claim 1 , wherein the compound is a compound of Formula I-b.5. The compound of or a pharmaceutically acceptable salt thereof claim 1 , wherein the compound is a compound of Formula I-c.6. The compound of or a pharmaceutically acceptable salt thereof claim 1 , wherein the compound is a compound of Formula I-d.7. The compound of or a pharmaceutically acceptable salt thereof claim 1 , wherein each of Rand Ris independently H or halogen; and each of Rand Ris independently H claim 1 , halogen claim 1 , —CN claim 1 , methyl claim 1 , Chaloalkyl claim 1 , methoxy claim 1 , or Chaloalkoxy.8. The compound of or a pharmaceutically acceptable salt thereof claim 1 , wherein each of Rand Ris H; Ris H; and Ris H claim 1 , halogen claim 1 , —CN claim 1 , methyl claim 1 , or Chaloalkyl.10. The compound of or a pharmaceutically acceptable salt thereof claim 9 , wherein Moiety Mis selected from the group consisting of quinolinyl claim 9 , isoquinolinyl claim 9 , 1H-imidazo[4 claim 9 ,5-c]pyridinyl claim 9 , imidazo[1 claim 9 ,2-a]pyridinyl claim 9 , 1H-pyrrolo[3 claim 9 ,2-c]pyridinyl claim 9 , imidazo[1 claim 9 ,2-a]pyrazinyl claim 9 , imidazo[2 claim 9 ,1-c][1 claim 9 ,2 claim 9 ,4]triazinyl claim 9 , imidazo[1 claim 9 ,5-a]pyrazinyl claim 9 , imidazo[1 claim 9 ,2-a]pyrimidinyl claim 9 , 1H-indazolyl claim 9 , 9H-purinyl claim 9 , imidazo[1 claim 9 ,2-a]pyrimidinyl claim 9 , [1 claim 9 ,2 claim 9 ,4]triazolo[1 claim 9 ,5-a]pyrimidinyl claim 9 , isoxazolo[5 ...

MAGNETO-THERMOELECTRIC GENERATOR FOR ENERGY HARVESTING

Provided is a magneto-thermoelectric generator (MTG) device for energy harvesting and more particularly a device for converting waste thermal heat from a photovoltaic cell into mechanical energy and ultimately into electrical energy. Embodiments operate on the principle of thermally-induced switching between open and closed states of a ferromagnetic switch to generate mechanical oscillations that cause strain in a piezoelectric material, resulting in the generation of electrical energy. A structure capable of providing a non-linear restoring force provides mechanical energy to the device, which is a significant improvement over prior art MTG devices employing a linear spring restorative force. The device is also provided as a hybrid photovoltaic (PV)/MTG energy harvester for scavenging heat from photovoltaic cells. The hybrid PV/MTG device is particularly useful for harvesting waste heat to boost power generation, extend flight duration, and provide thermal management aboard HALE platforms. 1. A magneto-thermoelectric generator comprising:(a) one or more heat sink;(b) one or more magnetic circuit;(c) one or more temperature-dependent magnetic materials;(d) one or more piezoelectric material, and one or more structure capable of providing a non-linear restorative force, together provided as successive layers adjacent to one another;wherein, during use, the magnetic circuit is disposed proximal to or in operable communication with one or more heat source;wherein, during use, the heat source and the heat sink are capable of providing a thermal gradient with a hot side and a cold side;wherein, the temperature-dependent magnetic material (i) has a thermally induced magnetic transition point within or near temperatures included in the thermal gradient, and (ii) is in operable communication with the structure for providing a non-linear restorative force and the piezoelectric material;wherein, during use, the temperature-dependent magnetic material, the structure for ...

Presenting Context-Based Guidance using Electronic Signs

Computer-implemented functionality is described herein for assisting a user in interacting with an environment. In one implementation, the functionality operates by: determining that a particular user is within a prescribed proximity to an electronic sign, or will be in prescribed proximity to the electronic sign, based on sensor information provided by one or more sensors within the environment; determining an identity of the user; determining at least one destination of the user based at least on calendar information; providing directions to the destination(s), to provide unfiltered direction information; optionally filtering the unfiltered direction information with respect to restriction information (e.g., privacy information, security information, etc.), to produce filtered direction information; composing sign information based on the filtered direction information; and sending the sign information to the electronic sign for presentation by the sign. 120-. (canceled)21. A method implemented by one or more computing devices , the method comprising:determining that a first user is within a prescribed proximity to a particular electronic sign, or will be in the prescribed proximity to the particular electronic sign, based at least on sensor information provided by one or more sensors within an environment;determining an identity of the first user;determining a first destination of the first user based at least on information provided in at least one data store;providing first direction information to direct the first user to the first destination;filtering the first direction information based at least on whether a second user is proximate to the particular electronic sign to obtain filtered first direction information;composing first sign information based at least on the filtered first direction information; andsending the first sign information to the particular electronic sign for presentation by the particular electronic sign,the first sign information being ...

ELECTRONIC LOCK

An electronic lock for securing a door or access panel. The electronic lock includes a housing and a plunger that is moveably mounted to the housing between a latched position of the electronic lock and an unlatched position of the electronic lock. A rotator is rotatably mounted to the housing between an unlocked position and a locked position. In the locked position of the rotator, the plunger is prevented from moving to the unlatched position, and, in the unlocked position of the rotator, the plunger is permitted to move to the unlatched position. A motor has an output shaft that is configured to rotate the rotator between the locked position and the unlocked position. A spring is configured to resist movement of the output shaft between the locked position and the unlocked position.

Portable Holder

A portable holder for securing a shaft of an item to a ground surface. The holder has a flexible base and a sleeve. The base has a center, a perimeter, a center hole disposed through the center and an upwardly projecting lip coupled to the perimeter. The base has a plurality of openings spaced around the perimeter for use with one or more stakes. The sleeve is coupled to the base and configured to receive a portion of the shaft. The sleeve has an internal bore aligned with the center hole in the base. When the shaft is received by the sleeve, the shaft passes through the bore, through the center hole, and into the ground surface. The sleeve has an inner surface and an outer surface, the inner surface having a plurality of gripping protrusions, and a plurality of securing straps coupled to the outer surface of the sleeve. 1. A portable holder for securing a shaft of an item to a ground surface , the holder comprising:a) a flexible base having a center and a perimeter, the base having a center hole disposed through the center and an upwardly projecting lip coupled to the perimeter, the base further comprising a plurality of openings spaced around the perimeter for use with one or more stakes to secure the holder to the ground surface; and i) an internal bore aligned with the center hole in the base such that when the shaft of the item is received by the sleeve, the shaft passes through the bore, through the center hole, and into the ground surface;', 'ii) an inner surface and an outer surface, the inner surface having a plurality of gripping protrusions disposed thereon; and', 'iii) a plurality of securing straps coupled to the outer surface of the sleeve for tightening the sleeve around the shaft disposed there through;, 'b) a flexible sleeve coupled to the base and configured to receive a portion of the shaft, the sleeve comprisingwherein the flexible sleeve is adjustable to accommodate a shaft having a plurality of shapes and/or sizes.2. The holder of claim 1 , ...

VEHICLE GLOVE BOX LATCH

A vehicle glove box latch includes a housing, a paddle pivotably connected to the housing, a rotor pivotably connected to the housing, a pawl coupled to the rotor and having an end that is engaged with an opening in the vehicle, and a lock barrel mounted to the housing for locking and unlocking the vehicle glove box latch. In a locked state of the lock barrel, the pawl cannot be disengaged from the opening in the vehicle. In an unlocked state of the lock barrel, the pawl can be disengaged from the opening for opening the vehicle glove box. The lock barrel, the rotor and the rotor mounting portion are concentrically aligned along an axis, which reduces the depth of the latch, which reduces the space in the glove box necessary for accommodating the latch, thereby resulting in an increase in the available storage space in the glove box. 1. A vehicle glove box latch for a vehicle glove box , the vehicle glove box latch comprising:a housing that is configured to be connected to a vehicle glove box;a user operated paddle that is pivotably connected to a paddle mounting portion of the housing, the paddle configured for movement between a home position and a deployed position;a rotor that is pivotably connected to a rotor mounting portion of the housing;at least one pawl coupled to the rotor and having an end that is configured to be engaged with an opening in the vehicle to which the vehicle glove box is mounted; anda lock barrel mounted to the housing for locking and unlocking the vehicle glove box latch, wherein, in a locked state of the lock barrel the at least one pawl cannot be disengaged from the opening in the vehicle, and in an unlocked state of the lock barrel, the at least one pawl can be disengaged from the opening in the vehicle using the paddle for opening the vehicle glove box;wherein the lock barrel, the rotor and the rotor mounting portion of the housing are concentrically aligned along an axis.2. The vehicle glove box latch of claim 1 , wherein the lock ...

Fuel efficient lubricating oils

The present invention relates to an engine oil lubricant composition for use in internal combustion engines comprising one or more molybdenum containing compounds that deliver 1-1000 ppm molybdenum to the finished oil, one or more phosphorus containing compounds that deliver 25-650 ppm phosphorus to the finished oil, and one or more poly(meth)acrylate viscosity index improvers (VI improvers) that may or may not be functionalized, for improved fuel economy and turbocharger related deposits. In addition, the composition comprises an antioxidant system which is carefully balanced to provide improved fuel economy, comprising an aminic antioxidant, a phenolic antioxidant and an ashless dithiocarbamate. Additionally, the formulated oil may contain a dispersant poly(meth)acrylate, in addition to the PAMA VI improver, to reduce the amount of traditional succinimide dispersants.

Remote control for displaying application data on dissimilar screens

A remote control service on a mobile device interrogates a program on another computing device to obtain metadata describing the structure of information being displayed on the computing device. The remote control service then calculates a different data structure that is used to display a subset of the data on the display screen of the mobile device.

DETERMINING MEDIA SIZE BY MONITORING USAGE

Devices and methods to determine media size in a printing device. Media being added to a media sheet tray of a printing device is detected. A size of the media in the tray is estimated based only on at least one of: a size of the media in the tray prior to the media being added, a size of the media recently used prior to the media being added, and a size of the media most frequently used. A selection of previously used sizes of media is displayed on a user interface. The selection comprises: the size of the media in the tray prior to the media being added, the size of the media recently used prior to the media being added, and the size of the media most frequently used. Confirmation of the size of the media added to the tray is received, on the user interface. 1. A method comprising:automatically detecting media being added to a media sheet tray of a printing device, said media sheet tray being devoid of sensors determining a size of said media; a size of said media in said media sheet tray prior to said media being added to said media sheet tray,', 'a size of said media recently used prior to said media being added to said media sheet tray, and', 'a size of said media most frequently used;, 'automatically estimating said size of said media in said media sheet tray based only on at least one of said size of said media in said media sheet tray prior to said media being added to said media sheet tray,', 'said size of said media recently used prior to said media being added to said media sheet tray, and', 'said size of said media most frequently used; and, 'automatically displaying on a user interface of said printing device a selection of previously used sizes of media, said selection comprisingreceiving, on said user interface, confirmation of said size of said media added to said media sheet tray.2. The method according to claim 1 , said detecting media being added to a media sheet tray of a printing device comprising detecting said media sheet tray being opened and ...

Disk Launcher System

A disk launcher system for effectively launching a disk. The disk launcher system generally includes a platform having an upper surface, a biasing member attached to the platform adapted to apply a biasing force to a disk positioned on the platform to launch the disk from the platform, a catch member movably positioned with respect to the platform adapted to selectively engage the disk, and a timing post extending upwardly from the upper surface of the platform that forces the disk to move to a side of the timing post after being released by the catch member resulting in rotation of the disk. A trigger may be connected to the catch member to allow for selective movement of the catch member by a user. A cover may also selectively cover a portion of the platform to help protect the user and guide the disk.

Extendable Self-Supporting Material

This disclosure relates to the field of self-supporting extendable materials such as tapes used for sealing, adhering two surfaces together, masking, medical tape, and the like; papers, vinyls, and decal substrates. More specifically, the disclosure is directed to coated extendable self-supporting materials, for example, adhesive tapes, papers, and adhesive sheets, and the manufacture of adhesive tapes and papers, wherein a length of tape or other material extends rigidly a certain distance and does not coil or curl onto itself, or curl or coil prematurely onto the receiving substrate. Yet, the material maintains flexibility to be pliable and generally to conform to a surface to which it may be applied. The material is available in sheet form or as roll goods. 1. A pressure sensitive tape comprising: a laminated material having an axial length and a longitudinal width;the laminated material having a substrate material layer having a first surface and a second surface, a first adhesive layer, a heat activated shrink film layer having a first surface and a second surface, and a second adhesive layer,wherein the first adhesive layer is disposed between the second surface of the substrate material layer and the first surface of the shrink film layer, and the second adhesive layer is disposed on the first surface of the substrate material layer or the second surface of the shrink film layer, and wherein the second adhesive layer comprises a pressure sensitive adhesive; andthe axial length of the laminated material has a curvature about the longitudinal width of the laminated material induced by heat activation of the shrink film layer, wherein the curvature is in the shape of an arc; andwherein the laminated material when extended is self-supporting, andwherein the substrate material is not a shrink film, and the substrate material and the activated shrink film cooperate to impart the curvature which imparts stiffness to the laminated material.2. The pressure sensitive ...

SCANNING PROBE MICROSCOPE

A scanning probe microscope with a first actuator () configured to move a feature in the form of a tip () so that the feature follows a scanning motion. A vision system () is configured to collect light from a field of view to generate image data. The field of view includes the feature and the light from the field of view travels from the feature to the vision system via the steering element (). A tracking control system ()bis configured to generate one or more tracking drive signals in accordance with stored reference data. A second actuator () is configured to receive the one or more tracking drive signals and move the steering element on the basis of the one or more tracking drive signals so that the field of view follows a tracking motion which is synchronous with the scanning motion and the feature remains within the field of view. An image analysis system () is configured to analyse the image data from the vision system to identify the feature and measure an apparent motion of the feature relative to the field of view. A calibration system is configured to adjust the stored reference data based on the apparent motion measured by the image analysis system. 1. A scanning probe microscope comprising:a first actuator configured to move a feature so that the feature follows a scanning motion;a steering element;a vision system configured to collect light from a field of view to generate image data, wherein the field of view includes the feature and the light from the field of view travels from the feature to the vision system via the steering element;a tracking control system configured to generate one or more tracking drive signals in accordance with stored reference data;a second actuator configured to receive the one or more tracking drive signals and move the steering element on the basis of the one or more tracking drive signals so that the field of view follows a tracking motion which is synchronous with the scanning motion and the feature remains within the ...

REMOTE DRONE CONFIGURATION SYSTEMS AND METHODS

Methods and systems are presented for making good use of recently obtained biometric data, for configuring propagule capsules (e.g. containing seeds or spores with growth media and other helpful materials) for deployment via drones so that each has an improved chance of survival, and for configuring drones or piloted craft for safe fleet deployment in remote locations. 1. A fleet support method comprising:obtaining a first current-limiting disconnect switch;obtaining one or more alternating-current-to-direct-current (AC/DC) converters;transporting aboard a single motor vehicle a first electrical power source, the first current-limiting disconnect switch, the one or more AC/DC converters, one or more direct-current (DC) buses, and one or more chargers to a first remote tract more than 100 meters from any conventional utility power grid conduit;configuring the first electrical power source to provide alternating-current (AC) power through the first current-limiting disconnect switch and to the one or more alternating-current-to-direct-current (AC/DC) converters at the first remote tract more than 100 meters from any conventional utility power grid conduit;routing DC power from the one or more AC/DC converters through the one or more DC buses to the one or more chargers so as to charge multiple battery units including first, second, third, and fourth lithium-based battery units therethrough simultaneously so that the multiple battery units are simultaneously charged at the first remote tract at an aggregate charging rate within an order of magnitude of 50-500 kilowatts, wherein the first and second lithium-based battery units are thereby charged simultaneously within respective adjacent first and second exhausted cubby holes separated by one or more materials having a nominal thickness within an order of magnitude of 1-5 centimeters and a nominal R factor therebetween within an order of magnitude of 1-10 m{circumflex over ( )}2 kelvin/watt, and wherein the first ...

RADIATION AND RADIOCHEMICALLY STERILIZED FIBER-REINFORCED, COMPOSITE URINOGENITAL STENTS

A radiation and radiochemically sterilized, multi-component, fiber-reinforced composite, absorbable/disintegratable urinogenital stent, such as an endoureteral stent, with radiomodulated residence time in the biological site of 1 to 10 weeks depending on the high energy radiation dose used for sterilization. 1. A multi-component disintegratable stent comprises:a tubular matrix having a body and at least one position retaining end;a central coil;a knitted mesh comprising an absorbable yarn; andwherein tubular matrix is reinforced with and impregnates the central coil and knitted mesh and the stent exhibits 1 to 10 week disintegration and strength retention profiles.2. A multi-component disintegratable stent as set forth in claim 1 , wherein the central coil is radiopaque and includes radiopaque microparticles.3. A multi-component disintegratable stent as set forth in wherein the at least one position-retaining end comprises a flexible extension of the body claim 1 , and has a loop shape with an open end parallel to an axis of the body after insertion wherein the loop can be made co-linear with the aid of an applicator.4. A multi-component disintegratable stent as set forth in wherein the matrix comprises an absorbable claim 1 , high molecular weight claim 1 , low-crystallinity claim 1 , segmented polyaxial copolyester exhibiting an inherent viscosity of from about 0.5 to about 2.0 dL/g and heat of fusion (ΔHf) of from about 2 to about 30 J/g and derived from 1-lactide and at least one additional monomer selected from the group consisting of glycolide claim 1 , trimethylene carbonate claim 1 , ε-caprolactone claim 1 , p-dioxanone claim 1 , 1 claim 1 ,5-dioxepan-2-one and a morpholinedione.5. A multi-component disintegratable stent as set forth in wherein the matrix comprises an absorbable claim 1 , segmented claim 1 , polyaxial copolyester and a high molecular weight claim 1 , hydrophilic polymeric additive having a molecular weight of about 1 to about 70 kDa claim 1 ...

ACTIVE APPAREL AND FABRIC AND COVERINGS

A fabric delivers active ingredients to a surface when the fabric includes a moist-vapor porous combination of fabric materials, and the fabric comprises at least 0.5% by total weight of at least one layer of the fabric of a superabsorbent polymer fiber. The superabsorbent polymer fiber contains an absorbed aqueous reservoir of an aqueous solution carrying the active ingredients. The superabsorbent fiber has a coating on its surface of an aqueous penetrable layer through which a liquid in the absorbed aqueous reservoir can migrate or flow, carrying the active ingredients onto an exposed surface of the superabsorbent polymer fiber, so that the active ingredients on the surface of the superabsorbent polymer can react or interact with an environment in contact with the active ingredients on the superabsorbent polymer fiber surface. 1. A fabric for delivering active ingredients to a surface when that fabric is positioned against the surface , the fabric comprising a moisture vapor porous combination of fabric materials , and the fabric comprises at least 0.5% by total weight of at least one layer of the fabric of a superabsorbent polymer fiber , and the superabsorbent polymer fiber contains an absorbed aqueous reservoir of an aqueous liquid solution carrying the active ingredients , and wherein the superabsorbent fiber has a coating on its surface through which the liquid solution in the absorbed aqueous reservoir can migrate or flow , carrying the active ingredients onto an exposed surface of the superabsorbent polymer fiber , so that the active ingredients in the liquid solution on the surface of the superabsorbent polymer can react or interact with an environment in contact with the active ingredients in the liquid solution on the surface of the superabsorbent polymer fiber.2. The fabric of wherein the coating on the surface of the superabsorbent polymer acts as a carrier that is able to absorb sufficient moisture from an ambient environment of 50% relative humidity ...

Heteroaromatic Compounds and their Use as Dopamine D1 Ligands

The present invention provides, in part, compounds of Formula I: 1. A method for treating Parkinson's disease in a human , which method comprises administering to said human a therapeutically effective amount of a D1 agonist with reduced D1R desensitization , wherein:{'sub': '50', 'the D1 agonist has an ECvalue of less than about 2 μM with respect to human D1 receptor;'}the D1 agonist desensitizes rat D1R cAMP signaling less than about 25% relative to Control, wherein Control is 0.1% DMSO in serum free neurobasal media; the percentage reduced D1R desensitization is measured by an assay using rat primary striatal neurons endogenously expressing rat D1Rs; and the assay comprises: a) pretreating rat D1Rs expressed in rat primary striatal neurons with Control for 30 minutes and then measuring the pretreated rat D1Rs′ ability in cAMP accumulation in the presence of SKF-81297 (1 μM) for 30 minutes, (b) pretreating rat D1Rs expressed in rat primary striatal neurons with 10 μM of the D1 agonist in serum free neurobasal media then measuring the pretreated rat D1Rs' ability in cAMP accumulation in the presence of SKF-81297 (1 μM) for 30 minutes, and (c) calculating percentage reduced desensitization by calculating percentage decrease in cAMP accumulation by the D1 agonist as measured in (b) relative to Control as measured in (a);the D1 agonist with reduced D1R desensitization is not a catechol derivative; andthe D1 agonist interacts significantly with the Ser188 but not significantly with the Ser202 residue of a human D1R when binding to the human D1R, wherein the interactions are measured by an assay substantially the same as the one in Example CC.2. The method of wherein the D1 agonist desensitizes rat D1R cAMP signaling less than about 20% relative to Control according to the assay as in .3. The method of wherein the D1 agonist interacts less strongly with the Asp103 residue or the Ser198 residue of the human D1R when binding to the human D1R wherein the interactions are ...

HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS

The present invention provides, in part, compounds of Formula I: 161-. (canceled)64. The compound of that is 6-{4-[(3-cyclopropylpyridin-2-yl)oxy]-2-methylphenyl}-1 claim 62 ,5-dimethylpyrimidine-2 claim 62 ,4(1H claim 62 ,3H)-dione claim 62 , or a pharmaceutically acceptable salt thereof.65. The compound of that is 6-{4-[(3-cyclopropylpyridin-2-yl)oxy]-2-methylphenyl}-1 claim 64 ,5-dimethylpyrimidine-2 claim 64 ,4(1H claim 64 ,3H)-dione.66. The pharmaceutically acceptable salt of the compound of .67. A compound that is (−)-6-{4-[(3-cyclopropylpyridin-2-yl)oxy]-2-methylphenyl}-1 claim 64 ,5-dimethylpyrimidine-2 claim 64 ,4(1H claim 64 ,3H)-dione claim 64 , or a pharmaceutically acceptable salt thereof.68. The compound of that is (−)-6-{4-[(3-cyclopropylpyridin-2-yl)oxy]-2-methylphenyl}-1 claim 67 ,5-dimethylpyrimidine-2 claim 67 ,4(1H claim 67 ,3H)-dione.6967. The pharmaceutically acceptable salt of the compound of claim of .70. The compound that is 6-{4-[(3-chloro-5-methylpyridin-2-yl)oxy]-2-methylphenyl}-1 claim 62 ,5-dimethylpyrimidine-2 claim 62 ,4(1H claim 62 ,3H)-dione claim 62 , or a pharmaceutically acceptable salt thereof.71. The compound of that is 6-{4-[(3-chloro-5-methylpyridin-2-yl)oxy]-2-methylphenyl}-1 claim 70 ,5-dimethylpyrimidine-2 claim 70 ,4(1H claim 70 ,3H)-dione.72. The pharmaceutically acceptable salt of the compound of .73. A compound that is (−)-6-{4-[(3-chloro-5-methylpyridin-2-yl)oxy]-2-methylphenyl}-1 claim 70 ,5-dimethylpyrimidine-2 claim 70 ,4(1H claim 70 ,3H)-dione claim 70 , or a pharmaceutically acceptable salt thereof.74. The compound of that is (−)-6-{4-[(3-chloro-5-methylpyridin-2-yl)oxy]-2-methylphenyl}-1 claim 73 ,5-dimethylpyrimidine-2 claim 73 ,4(1H claim 73 ,3H)-dione.7573. The pharmaceutically acceptable salt of the compound of claim of .76. The compound of that is 6-(4-{[3-(difluoromethoxy)pyridin-2-yl]oxy}-2-methylphenyl)-1 claim 62 ,5-dimethylpyrimidine-2 claim 62 ,4(1H claim 62 ,3H)-dione claim 62 , or a pharmaceutically ...

DETERMINING HIGH TONER USAGE

According to a method herein, a number of pixels marked and times of printing are automatically determined for a plurality of images. A time-based moving window of pixel counts for a subset of the plurality of images being contiguously processed in a current time window is automatically calculated, based on the number of pixels marked and the times of printing of the subset of the plurality of images processed in the current time window. Marking material usage to print the plurality of images for the current time window is automatically determined, based on the time-based moving window of pixel counts of the current time window. The method automatically determines if the marking material usage for the current time window exceeds a threshold. A notification is automatically output if the marking material usage for the current time window exceeds the threshold. 1. A method comprising:automatically forming a queue of image descriptors, using a computerized device, each image descriptor in said queue comprising a number of pixels marked on an image and a time of marking said image using an image marking device, said queue comprising said image descriptors recorded over a selected time window; automatically determining a queue window based on said new time mark and said selected time window, using said computerized device, and', 'automatically calculating a total number of pixels marked on images for all image descriptors in said queue window, using said computerized device; and, 'responsive to a new image descriptor being added to said queue, said new image descriptor having a new time markautomatically determining toner usage in said queue window based on said total number of pixels, using said computerized device.2. The method according to claim 1 , further comprising:comparing said toner usage to a maximum toner dispense rate for said image marking device, using said computerized device.3. The method according to claim 1 , further comprising:automatically determining ...

HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS

The present invention provides, in part, compounds of Formula I: 161-. (canceled)62. A compound selected from the group consisting of:6-{4-[(3-chloro-5-fluoropyridin-2-yl)oxy]-2-methylphenyl}-1,5-dimethylpyrimidine-2,4(1H,3H)-dione;1,5-dimethyl-6-(2-methyl-4-{[3-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)pyrimidine-2,4(1H,3H)-dione; and6-{4-[(3-chloropyridin-2-yl)oxy]-2-methylphenyl}-1,5-dimethylpyrimidine-2,4(1H,3H)-dione,or a pharmaceutically acceptable salt thereof.63. The compound or pharmaceutically acceptable salt of wherein the compound or salt is a compound selected from the group consisting of:(−)-6-{4-[(3-chloro-5-fluoropyridin-2-yl)oxy]-2-methylphenyl}-1,5-dimethylpyrimidine-2,4(1H,3H)-dione;(+)-6-{4-[(3-chloro-5-fluoropyridin-2-yl)oxy]-2-methylphenyl}-1,5-dimethylpyrimidine-2,4(1H,3H)-dione;(−)-1,5-dimethyl-6-(2-methyl-4-{[3-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)pyrimidine-2,4(1H,3H)-dione;(+)-1,5-dimethyl-6-(2-methyl-4-{[3-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)pyrimidine-2,4(1H,3H)-dione;(−)-6-{4-[(3-chloropyridin-2-yl)oxy]-2-methylphenyl}-1,5-dimethylpyrimidine-2,4(1H,3H)-dione; and(+)-6-{4-[(3-chloropyridin-2-yl)oxy]-2-methylphenyl}-1,5-dimethylpyrimidine-2,4(1H,3H)-dione,or a pharmaceutically acceptable salt thereof.64. The compound or pharmaceutically acceptable salt of that is 6-{4-[(3-chloro-5-fluoropyridin-2-yl)oxy]-2-methylphenyl}-1 claim 62 ,5-dimethylpyrimidine-2 claim 62 ,4(1H claim 62 ,3H)-dione or a pharmaceutically acceptable salt thereof.65. The compound of that is 6-{4-[(3-chloro-5-fluoropyridin-2-yl)oxy]-2-methylphenyl}-1 claim 64 ,5-dimethylpyrimidine-2 claim 64 ,4(1H claim 64 ,3H)-dione.66. The pharmaceutically acceptable salt of that is a pharmaceutically acceptable salt of 6-{4-[(3-chloro-5-fluoropyridin-2-yl)oxy]-2-methylphenyl}-1 claim 64 ,5-dimethylpyrimidine-2 claim 64 ,4(1H claim 64 ,3H)-dione.67. A compound that is (−)-6-{4-[(3-chloro-5-fluoropyridin-2-yl)oxy]-2-methylphenyl}-1 claim 64 ,5-dimethylpyrimidine-2 claim 64 ,4( ...

Heteroaromatic compounds and their use as dopamine d1 ligands

The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D1-mediated (or D1-associated) disorders including, e.g., schizophrenia (e.g., its cognitive and negative symptoms), schizotypal personality disorder, cognitive impairment (e.g., cognitive impairment associated with schizophrenia, AD, PD, or pharmacotherapy therapy), ADHD, Parkinson's disease, anxiety, and depression.

Heteroaromatic Compounds and their Use as Dopamine D1 Ligands

The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof and N-oxides thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds and the uses of such compounds for the treatment of D1-mediated (or D1-associated) disorders including cognitive and motivational impairments and negative symptoms associated with illnesses such as schizophrenia, depression, bipolar disorder, Parkinson's disease, Mild cognitive impairment (MCI), Alzheimer's disease, lupus, Huntington's disease, Parkinson's, dyskinesia, ADHD, post-traumatic stress disorder, autism spectrum disorder, treatment-resistant depression, major depressive disorder (MDD), drug dependence, Tourette's syndrome, tardive dyskinesias as well as impairments associated with age, chronic stress, sleep deprivation, combat, chronic fatigue; endocrine or metabolic diseases such as hyperglycemia, dislipidemia, diabetes, obesity, and sepsis; and cardiovascular disorder such as hypertension.

Personal independent mobility and lift device

A mobility device with sit and stand assist for providing disabled individuals with the ability to rise from a sitting position and move about without the aid of an assistant. The mobility device with sit and stand assist generally includes a motorized and steerable Drive Carriage Assembly, a Trailing Cart Assembly attached to the Drive Carriage Assembly, an Outrigger Assembly attached to the Trailing Cart Assembly, a Lift Arm Assembly attached to the Outrigger Assembly, a Lift Arm Locking Bolt Assembly attached to the Lift Arm Assembly, a Knee Brace Assembly attached to the Trailing Cart Assembly, a Control Assembly attached to the Lift Arm Assembly, and a User Connection Group comprised of various components designed to enable the user to comfortably connect himself/herself to the Device such that the user might be able to utilize and benefit from the Device.

RADIOPAQUE IODINATED AND IODIDE-CONTAINING CRYSTALLINE ABSORBABLE ALIPHATIC POLYMERIC MATERIALS AND APPLICATIONS THEREOF

Radiopaque, iodinated, absorbable polyesters, polyester urethanes, and polyether-ester-urethanes with and without inorganic iodide micro-/nanoparticles dispersed or solubilized therein, and composite inorganic iodide micro-/nanoparticles in an absorbable polyester, polyester-urethane, polyester-ester, or polyether-ester urethane matrix are employed in medical devices and therapeutic compositions. 121-. (canceled)22. A medical device comprising a radiopaque coating located on the medical device , the radiopaque coating comprising a radiopaque , iodinated , absorbable , crystalline , 80-100% aliphatic polymer.23. The medical device of claim 22 , wherein the medical device is selected from the group consisting of an absorbable/disintegratable urinogenital stent claim 22 , an absorbable endovascular stent claim 22 , and an absorbable diagnostic device.24. The medical device of claim 22 , wherein the medical device is a catheter.25. The medical device of claim 22 , wherein the polymer comprises ester linkages.26. The medical device of claim 22 , wherein the polymer comprises chemical linkages selected from the group consisting of an aliphatic carbonate claim 22 , acyclic carbonate claim 22 , cycloaliphatic urethane claim 22 , acyclic aliphatic urethane claim 22 , cycloaliphatic carbonate claim 22 , aliphatic ether claim 22 , and aliphatic anhydride.27. The medical device of claim 22 , wherein the polymer has a molecular weight of at least 5 kDa and a heat of fusion exceeding 10 J/g.28. A method of producing a radiopaque absorbable composite comprising:forming an organic absorbable crystalline matrix from a halogen-hydroxylic initiator and at least one cyclic monomer;dispersing a water soluble radiopaque halogen salt in the form of microparticles or nanoparticles into the organic absorbable crystalline matrix to provide a dispersion; andforming a radiopaque absorbable composite from the dispersion.29. The method of claim 28 , wherein the organic absorbable crystalline ...

METHODS, SYSTEMS AND DEVICES FOR PREDICTING RESERVOIR PROPERTIES

Methods, devices and computer-readable media for predicting hydrocarbon production rates for a subterranean formation are described. A method includes: receiving or generating, by at least one processor, well logs from data collected from at least one well in the subterranean formation; generating from the well logs a predicted production rate log for the at least one well; receiving, by the at least one processor, a field dataset for the subterranean formation, the field dataset including field data at locations in 3-dimensions of a volume of the subterranean formation; identifying the predicted production rate log for the at least one well as one or more targets, determining a transform relating the field data and the predicted rate log for the at least one well; and using the transform, generating a predicted production rate for each location of the volume of the subterranean formation. 1. A method of predicting hydrocarbon production rates for a subterranean formation , the method comprising:receiving or generating, by at least one processor, well logs from data collected from at least one well in the subterranean formation;generating from the well logs a predicted production rate log for the at least one well;receiving, by the at least one processor, a field dataset for the subterranean formation, the field dataset including field data at locations in 3-dimensions of a volume of the subterranean formation;identifying the predicted production rate log for the at least one well as one or more targets, determining a transform relating the field data and the predicted rate log for the at least one well; andusing the transform, generating a predicted production rate for each location of the volume of the subterranean formation.2. The method of wherein determining the transform comprises applying at least one of a linear regression claim 1 , a genetic algorithm claim 1 , a neural network analysis claim 1 , or a multi-parameter estimation method.3. The method of ...

Heteroaromatic compounds and their use as dopamine d1 ligands

The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof and N-oxides of the foregoing; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds, salts or N-oxides, and their uses for treating D1-mediated (or D1-associated) disorders including, e.g., schizophrenia (e.g., its cognitive and negative symptoms), cognitive impairment (e.g., cognitive impairment associated with schizophrenia, AD, PD, or pharmacotherapy therapy), ADHD, impulsivity, compulsive gambling, overeating, autism spectrum disorder, MCI, age-related cognitive decline, dementia, RLS, Parkinson's disease, Huntington's chorea, anxiety, depression, MDD, TRD, and bipolar disorder.

Radiopaque iodinated and iodide-containing crystalline absorbable aliphatic polymeric materials and applications thereof

Radiopaque, iodinated, absorbable polyesters, polyester urethanes, and polyether-ester-urethanes with and without inorganic iodide micro-/nanoparticles dispersed or solubilized therein, and composite inorganic iodide micro-/nanoparticles in an absorbable polyester, polyester-urethane, polyester-ester, or polyether-ester urethane matrix are employed in medical devices and therapeutic compositions. 125-. (canceled)26. A radiopaque , absorbable composite of at least one type of radiopaque micro-/nanoparticles dispersed or solubilized in an organic absorbable crystalline polymeric matrix having a molecular weight of at least 5 kDa and a heat of fusion exceeding 10 J/g.27. A radiopaque claim 26 , absorbable composite as in wherein the at least one type of radiopaque micro-/nanoparticles comprises 10 to 70 percent of the total mass of the composite.28. A radiopaque claim 26 , absorbable composite as in wherein the at least one type of radiopaque micro-/nanoparticles comprises an iodide or bromide salt.29. A radiopaque absorbable composite as in wherein the organic absorbable crystalline polymeric matrix is an absorbable polyester derived from at least one cyclic monomer selected from the group consisting of l-lactide claim 26 , glycolide claim 26 , trimethylene carbonate claim 26 , p-dioxanone claim 26 , 1 claim 26 ,5-dioxepan-2-one claim 26 , ε-caprolactone claim 26 , a morpholinedione or combinations thereof.30. A radiopaque claim 26 , absorbable composite as in wherein the organic absorbable crystalline matrix is selected from the reaction product of a halogen-hydroxylic initiator claim 26 , and at least one monomer selected from the group consisting of 1-lactide claim 26 , glycolide claim 26 , trimethylene carbonate claim 26 , p-dioxanone claim 26 , 1 claim 26 ,5-dioxepan-2-one claim 26 , ε-caprolactone claim 26 , and a morpholinedione claim 26 , the polyester having a molecular weight exceeding 5 kDa and a heat of fusion of at least 10 J/g claim 26 , and the reaction ...

METHODS FOR PRODUCING AND USING REJUVENATED RED BLOOD CELLS

Methods for treating blood. The methods comprise obtaining whole blood from a donor, mixing the whole blood with a red blood cell enhancement composition, and incubating the mixture of whole blood and red blood cell enhancement composition. The method can be performed at a time proximate to the time of obtaining blood from the donor, or after the blood has been stored for a period of time. The method rejuvenates red blood cells. 127.-. (canceled)28. A method of processing a blood component , the method comprising:adding a red blood cell (RBC) enhancement composition comprising inosine, adenine, pyruvate, a phosphate mixture, or a combination thereof, to a blood component comprising RBCs;incubating the blood component and the RBC enhancement composition for a period between about 30 minutes and 90 minutes to form a treated RBC composition; and{'sub': '2', 'measuring the pOat 50% oxygen saturation (p50) of the treated RBC composition during the period.'}29. The method of claim 28 , wherein the RBC enhancement composition comprises about 25 g/L to about 30 g/L inosine claim 28 , about 0.2 g/L to about 2 g/L adenine claim 28 , about 5 g/L to about 15 g/L pyruvate claim 28 , and about 17 g/L to about 23 g/L sodium phosphate claim 28 , or a combination thereof.30. The method of claim 28 , wherein the RBC enhancement composition comprises about 27 g/L inosine claim 28 , about 11 g/L pyruvate claim 28 , about 0.7 g/L adenine claim 28 , and about 21 g/L sodium phosphate.31. The method of claim 30 , wherein the sodium phosphate comprises about 6.2 g/L sodium phosphate claim 30 , monobasic claim 30 , monohydrate; and about 14.6 g/L sodium phosphate claim 30 , dibasic claim 30 , heptahydrate.32. The method of claim 28 , wherein the incubating is at a temperature between 1° C. and about 45° C.33. The method of claim 28 , wherein the incubating is not in a water bath.34. The method of claim 28 , wherein the blood component and the RBC enhancement composition are mixed during the ...

Presenting Context-Based Guidance using Electronic Signs

Computer-implemented functionality is described herein for assisting a user in interacting with an environment. In one implementation, the functionality operates by: determining that a particular user is within a prescribed proximity to an electronic sign, or will be in prescribed proximity to the electronic sign, based on sensor information provided by one or more sensors within the environment; determining an identity of the user; determining at least one destination of the user based at least on calendar information; providing directions to the destination(s), to provide unfiltered direction information; optionally filtering the unfiltered direction information with respect to restriction information (e.g., privacy information, security information, etc.), to produce filtered direction information; composing sign information based on the filtered direction information; and sending the sign information to the electronic sign for presentation by the sign. 1. A method , implemented by one or more computing devices , for assisting a user in interacting with an environment , comprising:determining that the user is within a prescribed proximity to an electronic sign, or will be in prescribed proximity to the electronic sign, based on sensor information provided by one or more sensors within the environment;determining an identity of the user;determining at least one destination of the user based at least on calendar information provided in at least one data store, the calendar information identifying at least one scheduled event that specifies the user as an attendee;providing directions to said at least one destination, to provide direction information;composing sign information based on the direction information; andsending the sign information to the electronic sign for presentation by the sign,the sign information being sent via an electronic message over a communication conduit.2. The method of claim 1 , further comprising:determining whether the user can be ...

Detecting a Wireless Signal Based on Context

A technique is described for efficiently detecting a wireless beacon signal emitted from a beacon-emitting mechanism, and thereby reducing consumption of power. The technique operates by selectively increasing detection activity when a detection event is likely to occur, and decreasing it otherwise. The technique leverages calendar information as one factor in determining when a detection event is likely to occur. The technique can also vary the detection activity based on location information (identifying the location of a user) and/or motion information (describing the motion of the user). 1. A method , implemented by at least one electronic device , for detecting a wireless signal , comprising:receiving activation instructions from a mode-selecting component, the mode-selecting component generating the activation instructions, for a particular user, based at least on calendar information that identifies at least one scheduled event;choosing a detection rate to be applied at a given time based on the activation instructions; andperforming a detection activity at the detection rate to enable detection of a wireless signal emitted by a beacon-emitting mechanism, checking, at the detection rate, to determine whether the wireless signal is present in a local environment; and/or', 'broadcasting, at the detection rate, the wireless signal into the local environment., 'said performing comprising one or more of2. The method of claim 1 , wherein the method is performed by a user computing device carried by the particular user.3. The method of claim 2 ,wherein the user computing device includes a beacon-sensing mechanism that is configured to check, at the detection rate, for the wireless signal in the local environment, andwherein the beacon-emitting mechanism is placed at a predetermined location in the local environment, and broadcasts, at the detection rate, the wireless signal into the local environment.4. The method of claim 2 ,wherein the beacon-emitting mechanism is ...

METHODS FOR REJUVINATING RED BLOOD CELLS

Methods and a system for transfusing blood to a mammalian subject. The method includes obtaining a volume of donated red blood cells (RBCs), adding an enhancement composition to the RBCs to form a treated blood composition, incubating the treated blood composition to form an incubated blood composition, and administering the incubated blood composition to a patient. The system includes a functionally-closed, sterile Y-type tube set. 125-. (canceled)26. A method for processing a blood component comprising the steps of:adding an enhancement composition to a volume comprising red blood cells (RBCs) to form an RBC composition, wherein the enhancement composition comprises inosine, adenine, pyruvate, sodium phosphate, or a mixture thereof.incubating the RBC composition for a period to form a treated RBC composition, including mixing the RBC composition during the incubating.27. The method of claim 26 , wherein the RBC enhancement composition comprises about 25 g/L to about 30 g/L inosine claim 26 , about 0.2 g/L to about 2 g/L adenine claim 26 , about 5 g/L to about 15 g/L pyruvate claim 26 , and about 17 g/L to about 23 g/L sodium phosphate claim 26 , or a combination thereof.28. The method of claim 26 , wherein the RBC enhancement composition comprises about 27 g/L inosine claim 26 , about 11 g/L pyruvate claim 26 , about 0.7 g/L adenine claim 26 , and about 21 g/L sodium phosphate.29. The method of claim 28 , wherein the sodium phosphate comprises about 6.2 g/L sodium phosphate claim 28 , monobasic claim 28 , monohydrate; and about 14.6 g/L sodium phosphate claim 28 , dibasic claim 28 , heptahydrate.30. The method of claim 26 , wherein the incubating is at a temperature between 1° C. and about 45° C.31. The method of claim 28 , wherein the incubating is not in a water bath.32. The method of claim 28 , wherein the mixing includes swirling claim 28 , shaking claim 28 , rotating claim 28 , or agitating the RBC composition.33. The method of claim 28 , wherein the period ...

ABSORBABLE CRYSTALLINE COPOLYESTER-BASED BIOACTIVE HYDROFORMING LUMINAL LINER COMPOSITIONS

Bioactive, hydroforming luminal liner compositions are formed of high molecular weight crystalline, absorbable copolyesters dissolved in a liquid derivative of a polyether glycol that undergoes transformation into a tissue-adhering, resilient interior cover or liner for the controlled release of its bioactive payload at clinically compromised conduits in humans as in the case of bacteria- and yeast-infected vaginal canals, esophagi, and arteries following angioplasty. 1. A bioactive , hydroforming , luminal liner composition comprising at least one crystalline , absorbable copolyester having a heat of fusion of at least 10 J/g and a molecular weight of greater than of 20 kDa; at least one liquid derivative of a polyether glycol; and at least one bioactive agent comprising an antifungal agent selected from the group consisting of ketoconazole , miconazole , voriconazole , and fluconazole.2. A bioactive claim 1 , hydroforming luminal liner composition as in as an antifungal formulation for treating yeast infections in humans claim 1 , the yeast infections selected from vaginal yeast infections and esophageal yeast infections.3. A bioactive claim 1 , hydroforming claim 1 , luminal liner composition comprising at least one crystalline claim 1 , absorbable copolyester having a heat of fusion of at least 10 J/g and a molecular weight of greater than of 20 kDa; at least one liquid derivative of a polyether glycol; and at least one bioactive agent comprising an antibacterial agent selected from the group consisting of metronidazole claim 1 , clindamycin claim 1 , doxycycline claim 1 , and tobramycin.4. A bioactive claim 3 , hydroforming luminal liner composition as in as an antibacterial formulation for treating bacterial infection in humans claim 3 , the bacterial infections selected from vaginal bacterial infections and esophageal bacterial infections.5. A bioactive claim 2 , hydroforming luminal liner composition as in further including an applicator kit for delivering ...

MAGNETOTHERMAL PUMP DEVICE AND METHOD OF OPERATION

Magnetothermal pump devices are provided. Such devices can operate on the principle of thermally induced switching between open and closed states of a magnetic switch to generate mechanical oscillations. Exemplary devices provided include a thermal gradient and a magnet with a Curie temperature at or within this gradient. When the soft magnet is below the Curie temperature, it has sufficient magnetic force to bind a hard magnet at the hot side of the gradient. Heating of the magnet at the hot side causes it to exceed its Curie temperature, resulting in loss of magnetic attraction. At this stage, a restorative force exceeds the magnetic force, causing the magnet to shift to the cold side of the gradient, which oscillations can be used to pump fluid. Any magnetic transition that results in a change in the vector nature of the magnetic moment of the soft magnetic material can be employed. 1. A magnetothermal pump comprising:a first magnetic material capable of being disposed proximal to a heat source;a heat sink;a means for providing a restorative force;a second magnetic material disposed between said heat source and said heat sink and in operable communication with said means for providing a restorative force;optionally a conduit;optionally means for controlling directional flow;wherein said heat source and said heat sink together provide a thermal gradient comprising respectively a hot side and a cold side;wherein during operation said second magnetic material has a thermally induced magnetic transition point within or near temperatures included in said thermal gradient and oscillates between a closed position and an open position.2. The pump of claim 1 , wherein during operation said second magnetic material is capable of binding to said first magnetic material at temperatures below its magnetic transition point through an attractive magnetic force to achieve a closed position; and capable of unbinding to said first magnetic material at temperatures above its ...

EVENT-TRIGGERED CONTROL OF BEACON BROADCASTS

Broadcasts from beacon devices each of which is disposed in a known different physical location within a venue are controlled. Scheduling information for events scheduled to take place at the venue may be collected from calendar management sources and analyzed. Notification of an emergent event associated with the venue or its geographic location may also be received from emergent event notification sources and analyzed. The result of these analyses and the knowledge of the physical location of each of the beacon devices are used to generate a set of broadcast rules for each of the beacon devices, where these rules specify one or more beacon signals to be periodically broadcast by the beacon device and the timing by which these signals are to be broadcast. For each of the beacon devices, the set of broadcast rules for the beacon device is downloaded to the beacon device. 1. A system for controlling broadcasts from one or more beacon devices each of which is disposed in a known different physical location within a venue , comprising: collect scheduling information for one or more events that are scheduled to take place at the venue from one or more calendar management sources,', 'analyze said collected scheduling information,', 'use the result of said analysis and the knowledge of the physical location of each of the beacon devices to generate a set of broadcast rules for each of the beacon devices, said rules specifying one or more beacon signals to be periodically broadcast by the beacon device and the timing by which said signals are to be broadcast, and', 'for each of the beacon devices, download the set of broadcast rules for the beacon device to the beacon device., 'a beacon controller comprising one or more computing devices, said computing devices being in communication with each other via a computer network whenever there is a plurality of computing devices, and a computer program having a plurality of sub-programs executable by said computing devices, said ...

Heteroaromatic Compounds and their Use as Dopamine D1 Ligands

The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof and N-oxides thereof; processes and intermediates for preparation of; and compositions and uses thereof. The present invention further provides D1 agonists with reduced D1R desensitization, D1 agonists with a reduced β-arrestin recruitment activity relative to Dopamine, D1 agonists interacting significantly with the Ser188 but not significantly with the Ser202 of a D1R when binding to the D1R, D1 agonists interacting less strongly with the Asp103 and interacting less strongly with the Ser198 of a D1R when binding to the D1R, and their uses.

DYNAMICALLY MANAGING A LISTEN LIST OF BEACON AWARE DEVICES

The described technology provides a system and method for dynamically managing a listen list for beacon aware devices. A mobile device may be configured to listen for one or more beacon UUIDs based on a listen list. A contextual change detected by the mobile device may trigger a collection of additional contextual information and update to the listen list based on the additional contextual information. Using the described technology, the mobile device may use a limited set of beacon UUIDs to improve micro-location granularity and enhance the mobile device's resources. 1. A location method comprising:storing in memory of a mobile device a listen list of one or more beacon universally unique identifiers (UUIDs) associated with an application executable on the mobile device;monitoring wirelessly received UUIDs transmitted by one or more beacons within a wireless-reception range of the mobile device, the mobile device being configured to perform a processor-executable operation upon detection of a beacon UUID stored in the listen list, the processor-executable operation being associated with the detected beacon UUID and the application; andupdating the listen list associated with the application and stored in the memory of the mobile device with a different set of one or more beacon UUIDs, responsive to a detected change in one or more monitored user contextual parameters satisfying one or more listen list update trigger conditions.2. The location method of claim 1 , wherein the one or more listen list update trigger conditions are based on a detected GPS location of the mobile device.3. The location method of claim 1 , wherein the one or more listen list update trigger conditions are based on a detection of a beacon UUID.4. The location method of claim 1 , wherein the one or more listen list update trigger conditions are based on a calendar event.5. The location method of claim 1 , wherein updating the listen list further comprises updating the one or more listen list ...

Rules-Based Identity Broadcast

Systems and methods for generating and broadcasting a dynamic identifier are presented. Based on the current context and rules established for accessing personal information, a dynamic identifier corresponding to a computer user is dynamically generated and provided to a computing device corresponding to the computer user. The computing device may broadcast the dynamic identifier to others. Upon receipt of a dynamic identifier, a party wishing to determine information regarding the broadcasting party must query an information service with the dynamic identifier. According to a set of rules and/or permissions established for the target computer user (broadcasting the dynamic identifier), accessible information is identified and returned to the requesting party.

VEHICLE ACCESSORY SUPPORT ASSEMBLY

A vehicle accessory support assembly for vehicles having a pair of opposed parallel seat rails, the vehicle accessory support assembly comprising a bar having a longitudinal axis, a first end portion and a second end portion, a first grip supported by the first end portion of the bar and configured to grip a first one of the pair of opposed parallel seat rails, a second grip slidably coupled to the second end portion of the bar and configured to grip a second one of the pair of opposed parallel seat rails and at least one support projecting from the bar, the support configured to support a vehicle accessory. 1. A vehicle accessory support assembly for use on any vehicle having a pair of opposed parallel seat rails after the vehicle has been initially sold by the manufacturer , the vehicle accessory support assembly comprising:a) a bar having a longitudinal axis, a first end portion, a second end portion, and one or more slots extending along a portion of the longitudinal axis of the bar;b) a first grip comprising a first engaging portion, the first grip slidably coupled to the first end portion of the bar and configured to grip a first one of the pair of opposed seat rails;c) a first opening disposed in the first engaging portion;d) a second grip comprising a second engaging portion, the second grip slidably coupled to the second end portion of the bar and configured to grip a second one of the pair of opposed seat rails;e) a second opening disposed in the second engaging portion;f) a first pair of fasteners configured to couple the first grip to the first end portion of the bar and the second grip to the second end portion of the bar via the one or more slots in the bar;g) a second pair of fasteners configured to couple the first and second grips to the first and second seat rails, wherein a first fastener of the second pair of fasteners is inserted through the first opening of the first engaging portion to couple the first grip to the first seat rail and a second ...

HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS

The present invention provides, in part, compounds of Formula I: 210-. (canceled)1217-. (canceled)1931-. (canceled)33. The compound of or a pharmaceutically acceptable salt thereof claim 32 , wherein Lis O.34. (canceled)35. The compound of or a pharmaceutically acceptable salt thereof claim 32 , wherein each of T claim 32 , T claim 32 , T claim 32 , and Tis independently selected from the group consisting of H claim 32 , F claim 32 , Cl claim 32 , Br claim 32 , —CN claim 32 , methoxy claim 32 , Cfluoroalkoxy claim 32 , methyl claim 32 , and Cfluoroalkyl claim 32 ,3637-. (canceled)38. The compound of or a pharmaceutically acceptable salt thereof claim 32 , wherein:{'sup': 1', '1, 'Xis CT;'}{'sup': '1', 'Tis H; and'}{'sup': '6', 'Tis H.'}40. The compound of or a pharmaceutically acceptable salt thereof claim 39 , wherein each of Rand Ris independently H or halogen.41. (canceled)42. The compound of or a pharmaceutically acceptable salt thereof claim 39 , wherein each of Rand Ris independently H or halogen; and each of Rand Ris independently H claim 39 , halogen claim 39 , —CN claim 39 , methyl claim 39 , Chaloalkyl claim 39 , methoxy claim 39 , or Chaloalkoxy.43. The compound of or a pharmaceutically acceptable salt thereof claim 39 , wherein each of Rand Ris H; Ris H; and Ris H claim 39 , halogen claim 39 , —CN claim 39 , methyl claim 39 , or Chaloalkyl.4445-. (canceled)4749-. (canceled)50. The compound of or a pharmaceutically acceptable salt thereof claim 46 , wherein Moiety Mis selected from the group consisting of quinolinyl claim 46 , isoquinolinyl claim 46 , 1H-imidazo[4 claim 46 ,5-c]pyridinyl claim 46 , imidazo[1 claim 46 ,2-a]pyridinyl claim 46 , 1H-pyrrolo[3 claim 46 ,2-c]pyridinyl claim 46 , imidazo[1 claim 46 ,2-a]pyrazinyl claim 46 , imidazo[2 claim 46 ,1-c][1 claim 46 ,2 claim 46 ,4]triazinyl claim 46 , imidazo[1 claim 46 ,5-a]pyrazinyl claim 46 , imidazo[1 claim 46 ,2-a]pyrimidinyl claim 46 , 1H-indazolyl claim 46 , 9H-purinyl claim 46 , imidazo[1 claim ...

Heteroaromatic compounds and their use as dopamine d1 ligands

The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D1-mediated (or D1-associated) disorders including, e.g., schizophrenia (e.g., its cognitive and negative symptoms), schizotypal personality disorder, cognitive impairment (e.g., cognitive impairment associated with schizophrenia, AD, PD, or pharmacotherapy therapy), ADHD, Parkinson's disease, anxiety, and depression.

HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS

The present invention provides, in part, compounds of Formula I: 2. The method of wherein Lis O or S.4. The method of wherein:{'sup': 10', '10', '10, 'sub': 1-4', '3-4', '1-4', '1-4', '1-4', '3-4', '1-4', '1-4', '1-4', '1-4', '1-4, 'Ris selected from the group consisting of —CN, Calkyl, Ccycloalkyl, cyclopropylmethyl, and cyclobutylmethyl, wherein the Calkyl of Ris optionally substituted with 1, 2, 3, or 4 substituents each independently selected from the group consisting of halogen, —OH, —CN, Calkoxy, and Chaloalkoxy; and wherein each of the Ccycloalkyl, cyclopropylmethyl, and cyclobutylmethyl of Ris optionally substituted with 1, 2, 3, or 4 substituents each independently selected from the group consisting of halogen, —OH, —CN, Calkyl, Chaloalkyl, Chydroxylalkyl, Calkoxy, and Chaloalkoxy;'}{'sup': 10A', '5', '6', '5', '6', '8', '8', '14', '14', '14', '14', '15', '14', '15, 'sub': 1-3', '1-3', '2-4', '2', '2', '2', '2', '2', '2', '2', '2, 'Ris selected from the group consisting of H, Calkyl, Chydroxylalkyl, Calkenyl, —S(═O)N(R)(R), —C(═O)—N(R)(R), —C(═O)—R, —C(═O)—OR, —C(R)—OH, —C(R)—OS(═O)H, —C(R)—OP(═O)(OH), —C(R)—OR, and —C(R)—OC(═O)—R; and'}{'sup': 10B', '10B', '10B, 'sub': 1-4', '3-4', '1-4', '1-4', '1-4', '3-4', '1-4', '1-4', '1-4', '1-4', '1-4, 'Ris selected from the group consisting of Calkyl, Ccycloalkyl, cyclopropylmethyl, and cyclobutylmethyl, wherein the Calkyl of Ris optionally substituted with 1, 2, 3, or 4 substituents each independently selected from the group consisting of halogen, —OH, —CN, Calkoxy, and Chaloalkoxy; and wherein each of the Ccycloalkyl, cyclopropylmethyl, and cyclobutylmethyl of Ris optionally substituted with 1, 2, 3, or 4 substituents each independently selected from the group consisting of halogen, —OH, —CN, Calkyl, Chaloalkyl, Chydroxylalkyl, Calkoxy, and Chaloalkoxy.'}6. The method of wherein:{'sup': 11', '11', '11, 'sub': 1-4', '3-4', '1-4', '1-4', '1-4', '3-4', '1-4', '1-4', '1-4', '1-4', '1-4, 'each Ris independently ...

COEXTRUDED ARC-INDUCED MATERIALS

A nasal dilator and method of making nasal dilators are provided. The dilator may have 1. A method of manufacturing a coextruded polymeric material having a longitudinal length and a longitudinal width , the method comprising:a) providing a first polymeric material;b) providing a second polymeric material; and,c) coextruding the first polymeric material and the second polymeric material to form a coextruded polymeric material; and, wherein the first polymeric material and second polymeric material have differing contraction properties when cooled following coextrusion,', 'wherein the first polymeric material, upon cooling, contracts at a greater ration than the second polymeric material,', 'wherein the cooling of the coextruded polymeric material following coextrusion results in the longitudinal length of the coextruded film having curvature in the shape of an arc about the longitudinal width;', 'wherein the arc has a concave side and a convex side; and,', 'wherein the shape of the arc about the longitudinal width is induced by cooperation between the first polymeric material and second polymeric material upon contraction of the first polymeric material., 'd) allowing the coextruded polymeric material to cool,'}2. The method of claim 1 , wherein the first polymeric material or second polymeric material comprises a polyester polymer.3. The method of claim 2 , wherein the polyester polymer is polyethylene terephthalate.4. The method of claim 1 , wherein the first material and second material comprise a polyester polymer.5. A method of manufacturing a coextruded polymeric material having a longitudinal length and a longitudinal width claim 1 , the method comprising:a) providing a first polymeric material;b) providing a second polymeric material having a first surface and a second surface;c) extruding the first polymeric material onto the first surface of the second polymeric material to form a coextruded polymeric material; and, wherein the first polymeric material and ...

ANISOTROPIC MAGNETODIELECTRIC POLYMER MATRIX COMPOSITES AND METHODS OF MANUFACTURE

Polymer matrix composites normally consist of spherical or ellipsoidal reinforcement phases distributed randomly throughout the material. The spherical shape of the reinforcing materials reduces the effective electromagnetic properties of the reinforcement. Provided is a composite material which advantageously uses anisotropic electromagnetic properties of high aspect ratio loading using alignment to optimize the extrinsic effective electromagnetic property of the composite. Methods of manufacturing the composite are also described. 1. A method of fabricating a composite material , the method comprising:providing a polymer host matrix material; a) one or more types of high aspect ratio magnetic particles; and/or', 'b) one or more types of high aspect ratio dielectric particles;', 'using a non-isostatic mechanical force and optionally heat, aligning at least a portion of the high aspect ratio particles within the host matrix material to fabricate a composite material, wherein at least a portion of the high aspect ratio particles are aligned within the host matrix material in a manner to provide the composite material with a target level of permeability, permittivity, or dielectric loss., 'combining one or more of the following with the host matrix material2. The method of claim 1 , wherein the non-isostatic mechanical force is extrusion claim 1 , rolling claim 1 , or uniaxial compaction.3. The method of claim 1 , wherein the aligning provides for at least a portion of the high aspect ratio particles to be aligned parallel with one another or aligned to within 30 degrees of parallel with one another.4. The method of claim 3 , wherein at least 50% of the high aspect ratio particles of at least one phase of the composite material are aligned with one another within that phase.53. The method of claim 1 , wherein the aspect ratio of the magnetic particles and/or of the dielectric particles is or greater.6. The method of claim 1 , further comprising combining a plurality ...

Method and Structure for Nasal Dilator

A nasal dilator and method of making nasal dilators are provided. The dilator may have 1. A film having a longitudinal length and a longitudinal width , the film comprising:a first layer and a second layer;wherein the first layer comprises a first polymeric material and the second layer comprises a second polymeric material;wherein the first polymeric material and second polymeric material have differing contraction properties upon cooling;wherein the first polymeric material, upon cooling, contracts at a greater ratio than the second polymeric material; andwherein the first polymeric material and second polymeric material have been cooled so that the first polymeric material is in a contracted state;wherein the longitudinal length of the coextruded film has a curvature in the shape of an arc about the longitudinal width;wherein said arc has a concave side and a convex side;wherein the shape of the arc is induced by cooperation between the first polymeric material and second polymeric material upon contraction of the first material; and,wherein the first polymeric material is on the concave side of the arc and the second material is on the convex side of the arc.2. The film of claim 1 , wherein the first polymeric material or the second polymeric material comprises a polyester polymer.3. The film of claim 2 , wherein the polyester polymer is polyethylene terephthalate.4. The film of claim 1 , wherein the first polymeric material and the second polymeric material comprise a polyester polymer.5. A coextruded film having a longitudinal length and a longitudinal width claim 1 , the coextruded film comprising:a first polymeric material and a second polymeric material, wherein the first polymeric material and second polymeric material have differing contraction properties upon cooling following coextrusion, and wherein the first polymeric material contracts at a greater ratio than the second polymeric material;wherein the first polymeric material and second polymeric ...

HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS

The present invention provides, in part, compounds of Formula I: 2. The compound of claim 1 , or a pharmaceutically acceptable salt thereof claim 1 , wherein each of T claim 1 , T claim 1 , T claim 1 , and Tis independently selected from the group consisting of H claim 1 , F claim 1 , —CN claim 1 , methoxy claim 1 , Cfluoroalkoxy claim 1 , methyl claim 1 , and Cfluoroalkyl claim 1 ,3. The compound of claim 1 , or a pharmaceutically acceptable salt thereof claim 1 , wherein Tis H and Tis H.6. The compound of claim 1 , or a pharmaceutically acceptable salt thereof claim 1 , wherein:{'sup': '1', 'Xis N or CH;'}{'sup': 1', '2, 'sub': 1-4', '1-4', '1-4', '1-4', '3-4, 'each of Rand Ris independently selected from the group consisting of H, halogen, —CN, Calkyl, Chaloalkyl, Calkoxy, Chaloalkoxy, and Ccycloalkyl;'}{'sup': 3', '4', '5', '6', '8, 'sub': 1-4', '1-4', '1-4', '3-4, 'each of Rand Ris independently selected from the group consisting of H, halogen, —OH, —CN, Calkyl, Chaloalkyl, Chaloalkoxy, Ccycloalkyl, a 4- to 7-membered heterocycloalkyl, —N(R)(R), and —OR,'}{'sup': 5', '6, 'sub': 1-4', '1-4', '3-7, 'each of Rand Rindependently is H or selected from the group consisting of Calkyl, Chaloalkyl, and Ccycloalkyl;'}{'sup': 5', '6, 'sub': 1-4', '1-4', '3-6', '1-4', '1-4, 'or Rand Rtogether with the N atom to which they are attached form a 4- to 7-membered heterocycloalkyl or a 5-membered heteroaryl, each optionally substituted with 1, 2, or 3 substituents each independently selected from the group consisting of halogen, —CN, Calkyl, Calkoxy, Ccycloalkyl, Chaloalkyl, and Chaloalkoxy; and'}{'sup': '8', 'sub': 1-4', '3-6', '1-4', '1-4', '3-6', '1-4', '1-4, 'Ris selected from the group consisting of Calkyl, Ccycloalkyl, a 4- to 7-membered heterocycloalkyl, phenyl, and a 5- to 6-membered heteroaryl, each optionally substituted with 1, 2, or 3 substituents each independently selected from the group consisting of halogen, —CN, Calkyl, Chaloalkyl, Ccycloalkyl, Calkoxy, and ...

Heteroaromatic Compounds and their Use as Dopamine D1 Ligands

The present invention provides, in part, compounds of Formula I: 23-. (canceled)4. The compound of claim 1 , or an N-oxide thereof or a pharmaceutically acceptable salt of said compound or said N-oxide claim 1 , wherein Qis selected from 3-oxo-2H-pyridazinyl claim 1 , 1H-2-oxo-pyrimidinyl claim 1 , 1H-2-oxo-pyridinyl claim 1 , 2 claim 1 ,4(1H claim 1 ,3H)-dioxo-pyrimidinyl claim 1 , and 1H-2-oxo-pyrazinyl claim 1 , wherein each of the selections is optionally substituted with 1 claim 1 , 2 claim 1 , 3 claim 1 , or 4 independently selected R.6. The compound of claim 5 , or an N-oxide thereof or a pharmaceutically acceptable salt of said compound or said N-oxide claim 5 , wherein Rand Rare both H; Ris H; and Ris H claim 5 , —CN claim 5 , Br claim 5 , Calkyl claim 5 , or cyclopropyl.7. The compound of claim 6 , or an N-oxide thereof or a pharmaceutically acceptable salt of said compound or said N-oxide claim 6 , wherein Rand Rare each independently selected from the group consisting of H claim 6 , F claim 6 , Cl claim 6 , and Calkyl.8. The compound of claim 7 , or an N-oxide thereof or a pharmaceutically acceptable salt of said compound or said N-oxide claim 7 , wherein one of Rand Ris H; and the other of Rand Ris selected from the group consisting of H claim 7 , —OH claim 7 , —CN claim 7 , Cl claim 7 , F claim 7 , methyl claim 7 , ethyl claim 7 , CF claim 7 , CHF claim 7 , and —OCH.9. The compound of claim 8 , or an N-oxide thereof or a pharmaceutically acceptable salt of said compound or said N-oxide claim 8 , wherein each Ris independently selected from the group consisting of Calkyl claim 8 , Cfluoroalkyl claim 8 , oxo claim 8 , —OH claim 8 , Calkoxy claim 8 , and Chaloalkoxy; wherein the Calkyl is optionally substituted with 1 claim 8 , 2 claim 8 , 3 claim 8 , 4 claim 8 , or 5 substituents each independently selected from halogen claim 8 , OH claim 8 , Calkoxy claim 8 , —NH claim 8 , —NH(Calkyl) claim 8 , —N(Calkyl) claim 8 , azetidin-1-yl claim 8 , pyrrolidin-1- ...

METHODS AND SYSTEMS FOR DETECTING NONUNIFORMITIES IN A MATERIAL, COMPONENT, OR STRUCTURE

Methods of detecting non-uniformities in a material are described. Such methods can comprise inducing changes in strain state or changing the magnetic moment of a material and measuring magnetic flux leakage that is synchronous with the changes in strain state or magnetic moment, while simultaneously applying an external magnetic field to control the relative magnitude of the magnetic flux leakage. 1. A method of detecting a nonuniformity in a material , component , or structure , the method comprising inducing changes in strain state in a material , component , or structure and measuring magnetic flux leakage that is synchronous with the changes in strain state.2. A method of detecting a nonuniformity in a material , component , or structure , the method comprising changing the magnetic moment of a material , component , or structure through the Villari effect and measuring magnetic flux leakage that is synchronous with changes in the magnetic moment.3. The method of further comprising:applying periodic mechanical force to a material, component, or structure in a manner sufficient to induce changes in strain state in the material, component, or structure.4. The method of further comprising:exciting a material, component, or structure with periodic waves of ultrasonic energy in a manner sufficient to induce cycles of compression and tension in the material, component, or structure; andmeasuring magnetic flux leakage that is synchronous with the cycles of compression and tension.5. The method of further comprising:applying an external magnetic field to a material, component, or structure;inducing periodic changes in strain state in the material, component, or structure.6. The method of further comprising:applying an external magnetic field to a material, component, or structure;applying periodic mechanical force to the material, component, or structure in a manner sufficient to induce changes in strain state in the material.7. The method of further comprising: ...

RADIOLOGY DEVICE

A radiology device includes at least one gamma radiation sensor, an acquisition device arranged to acquire data from each gamma radiation sensor, a transmission device arranged to transmit the acquired data outside the device, at least one battery arranged to store electrical energy and to electrically supply each sensor, the acquisition device and the transmission device. The radiology device is arranged to be carried entirely by the user. An application of the present radiology device is the treatment of cancers by administration of radionuclides. 1. A radiology device , comprising:at least one detector of gamma radiation;acquisition means arranged in order to acquire data from each gamma radiation detector;transmission means arranged in order to transmit the acquired data to outside the device;at least one battery arranged in order to store electrical power and supply electricity to each detector, to the acquisition means and to the transmission means;the device being arranged in order to be worn in its entirety by a user; said device also comprising attachment means arranged in order to attach at least one of the detectors to a part of the user's body; andthe attachment means comprise a neck brace for at least one of the detectors.2. The device according to claim 1 , characterized in that the at least one gamma radiation detector comprises at least one first group and one second group claim 1 , each group comprising at least one gamma radiation detector claim 1 , the attachment means not being common to the first group and the second group claim 1 , so that:the attachment means comprise the neck brace for the first group; andthe second group is arranged in order to act as a measurement reference for the first group.3. The device according to claim 1 , characterized in that the transmission means are arranged in order to send data to outside the device by a wireless link claim 1 , preferably as they are acquired by the acquisition means.4. The device according to ...

HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS

The present invention provides, in part, compounds of Formula I: This application is a division of U.S. application Ser. No. 15/822,493 filed Nov. 27, 2017, which is in turn a continuation of Ser. No. 15/305,372 filed Oct. 20, 2016 (issued as U.S. Pat. No. 9,868,744 on Jan. 16, 2018), which in turn is a national phase filing under 35 U.S.C. § 371 of international patent application number PCT/162015/052672 filed Apr. 13, 2015, which in turn claims the benefit of priority to U.S. Provisional Patent Application Ser. No. 61/984,086 filed Apr. 25, 2014, the disclosure of each of these applications is hereby incorporated by reference in its entirety.The present invention generally relates to heteroaromatic compounds, which are dopamine D1 ligands, for example dopamine D1 agonists or partial agonists.Dopamine acts upon neurons through two families of dopamine receptors, D1-like receptors (D1Rs) and D2-like receptors (D2Rs). The D1-like receptor family consists of D1 and D5 receptors which are expressed in many regions of the brain. D1 mRNA has been found, for example, in the striatum and nucleus accumbens. See e.g., Missale C, Nash S R, Robinson S W, Jaber M, Caron M G “Dopamine receptors: from structure to function”, 78:189-225 (1998). Pharmacological studies have reported that D1 and D5 receptors (D1/D5), namely D1-like receptors, are linked to stimulation of adenylyl cyclase, whereas D2, D3, and D4 receptors, namely D2-like receptors, are linked to inhibition of cAMP production.Dopamine D1 receptors are implicated in numerous neuropharmacological and neurobiological functions. For example, D1 receptors are involved in different types of memory function and synaptic plasticity. See e.g., Goldman-Rakic P S et al., “Targeting the dopamine D1 receptor in schizophrenia: insights for cognitive dysfunction”, 174(1):3-16 (2004). Moreover, D1 receptors have been implicated in a variety of psychiatric, neurological, neurodevelopmental, neurodegenerative, mood, motivational, ...

Heteroaromatic compounds and their use as dopamine d1 ligands

The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D1-mediated (or D1-associated) disorders including, e.g., schizophrenia (e.g., its cognitive and negative symptoms), cognitive impairment (e.g., cognitive impairment associated with schizophrenia, AD, PD, or pharmacotherapy therapy), and Parkinson's disease.

Pipeline branch arrangement

A pipeline branch arrangement that forms a piggable-Y at the intersection with the trunkline and is oriented vertically relative to the trunkline. The approach piping to all legs of the piggable-Y are configured to incorporate 3D bend or larger radii as required. This arrangement permits the passage of foam pigs, hard pigs, and smart pigs. Rotation of the piggable-Y to the vertical plane configures all of the branch piping in the vertical plane, which permits the support sled width for pipe laying to be kept to a minimum. The arrangement of the 3D bends fore and aft of the piggable-Y aligns the trunkline ends in a co-linear manner. This permits the configuration to be installed by conventional S-Lay techniques.

Transfer curve tester for testing magnetic recording heads

A head testing apparatus is provided for testing an output of a magnetic data recording head. The apparatus includes first and second tester input terminals for coupling to the head, first and second input stages and an AC-coupled differential amplifier. The first input stage has a first buffer input, which is coupled to the first tester input terminal, a first buffer output and a plurality of parallel-connected buffer amplifiers coupled between the first buffer input and the first buffer output. The second input stage has a second buffer input, which is coupled to the second tester input terminal, a second buffer output and a plurality of parallel-connected buffer amplifiers coupled between the second buffer input and the second buffer output. The AC-coupled differential amplifier has first and second amplefier inputs coupled to the first and second buffer outputs through first and second capacitors, respectively, and has a measurement output.

Moisture absorbing fabrric blend

A moisture-retentive fabric medium includes a hydrophilic, thermoplastic polyester fiber as a blend of from 10-905% or 20-80% by total weight of textile fibers and 90-10% or 80-20% by total weight of hydrophilic textile fibers and less than 0.5% by weight of total fabric medium as microfibrillated cellulose fiber and less than 0.05% by weight superabsorbent polymers, the polyester having a melting point between 190-500 F when measured in accordance with ASTM D-3418.

Controlled wellhead buoy

A subsea system for the production of hydrocarbon reserves; the system includes a control wellhead buoy (10) that is used in deepwater operations f or offshore hydrocarbon production.

Nanocomposites, nanoporous polymer membranes and catalysts

Substituted morpholine compounds for the treatment of central nervous system disorders

This invention relates to compounds of the formulae (I), (II), (III), wherein R'- Re, A, X, and Z are defined as in the specification, pharmaceutical compositions containing them and their use in the treatment of central nervous system disorders.

Heteroaromatic compounds and their use as dopamine D1 ligands

The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D1-mediated (or D1-associated) disorders including, e.g., schizophrenia (e.g., its cognitive and negative symptoms), schizotypal personality disorder, cognitive impairment (e.g., cognitive impairment associated with schizophrenia, AD, PD, or pharmacotherapy therapy), ADHD, Parkinson's disease, anxiety, and depression.