METHOD AND APPARATUS FOR FACILITATING MANUFACTURING OF SEMICONDUCTOR DEVICE

A method for facilitating semiconductor device manufacturing may include the following steps: receiving a custom design data set, which complies with a first element-identification scheme; generating a compatible design data set using the custom design data set, wherein data elements in the compatible design data set correspond to data elements in the custom design data set, and wherein the compatible design data set is compatible with a dummy-pattern-data generation module; generating a first dummy-pattern data set using the dummy-pattern-data generation module and the compatible design data set; and generating a second dummy-pattern data set using the first dummy-pattern data set, wherein data elements in the second dummy-pattern data set correspond to data elements in the first dummy-pattern data set, and wherein the second dummy-pattern data set complies with the first element-identification scheme. 1. A method for facilitating manufacturing of a semiconductor device , the method comprising:receiving a custom design data set, wherein the custom design data set complies with a first element-identification scheme;generating a compatible design data set using hardware circuits and the custom design data set, wherein some data elements in the compatible design data set correspond to some data elements in the custom design data set, and wherein the compatible design data set is compatible with a dummy-pattern-data generation module;generating a first dummy-pattern data set using the hardware circuits, the dummy-pattern-data generation module, and the compatible design data set; andgenerating a second dummy-pattern data set using the hardware circuits and the first dummy-pattern data set, wherein some data elements in the second dummy-pattern data set correspond to some data elements in the first dummy-pattern data set, and wherein the second dummy-pattern data set complies with the first element-identification scheme.2. The method of comprising:manufacturing a dummy ...

METHODS FOR TREATING OBSTRUCTIVE SLEEP APNEA

The present invention relates to methods for treating obstructive sleep apnea (OSA), alleviating a negative OSA symptom, reducing snoring, or improving quality of life in a subject, comprising administering to the subject an effective amount of a pharmaceutical composition comprising pyridostigmine before sleep. Also provided are related medicaments as well as methods for preparing the medicaments. 1. A method for treating obstructive sleep apnea (OSA) in a subject in need thereof , comprising administering to the subject an effective amount of a pharmaceutical composition comprising pyridostigmine before sleep.2. The method of claim 1 , wherein apnea claim 1 , hypopnea claim 1 , snoring claim 1 , or low oxygen saturation events in the subject is reduced.3. The method of claim 1 , wherein sleep quality or daytime quality of life of the subject is improved.4. The method of claim 1 , wherein the effective amount of the pharmaceutical composition is selected to provide a target serum concentration of pyridostigmine in the subject in the range of 2-150 ng/ml for at least one hour.5. The method of claim 4 , wherein the target serum concentration is in the range of 3-60 ng/ml.6. The method of claim 4 , wherein the target serum concentration is in the range of 3-45 ng/ml.7. The method of claim 4 , wherein the target serum concentration is in the range of 3-30 ng/ml.8. The method of claim 4 , wherein the target serum concentration is in the range of 3-15 ng/ml.9. The method of claim 4 , wherein the target serum concentration is maintained for at least three hours.10. The method of claim 1 , wherein the pharmaceutical composition comprises 30-360 mg pyridostigmine.11. The method of claim 1 , wherein the pharmaceutical composition is administered to the subject within 2 hours before sleep.12. The method of claim 1 , wherein the pharmaceutical composition is administered to the subject in a single dose.13. The method of claim 1 , wherein the pharmaceutical composition further ...

Thermoplastic Polymer Blends Comprising Dynamically Crosslinked Polyurethane in an Olefin Polymer Matrix

Compatibilized blends comprising a first phase comprising a thermoplastic olefin polymer and a second phase comprising a crosslinked, thermoplastic polyurethane are provided. The first phase is a continuous phase and the second phase can be co-5 continuous with the first phase, or dispersed as a non-continuous phase in the first phase. The blends further include a phenolic resole resin which at least partially crosslinks the thermoplastic polyurethane and acts as a compatibilizer for the olefin polymer and the thermoplastic polyurethane. 1. A compatibilized blend comprising:(a) a continuous phase comprising a thermoplastic olefin polymer;(b) a dispersed or co-continuous phase comprising a crosslinked, thermoplastic polyurethane dispersed in the continuous phase or co-continuous with the continuous phase; and(c) a phenolic resole resin crosslinking the thermoplastic polyurethane, wherein the phenolic resole resin also acts as a compatibilizer for the thermoplastic olefin polymer and the polyurethane.2. The blend of claim 1 , in which the thermoplastic olefin polymer is a non-polar olefin polymer.3. The blend of further comprising at least one flame retardant.4. The blend of further comprising at least one additional compatibilizer.6. The blend of comprising 5 to 75 weight percent thermoplastic olefin polymer claim 1 , based on the total weight of the blend claim 1 , 5 to 75 weight percent thermoplastic polyurethane claim 1 , based on the total weight of blend claim 1 , and 0.1 to 10 weight percent phenolic resole resin claim 1 , based on the total weight of blend.7. The blend of claim 1 , in which the thermoplastic olefin polymer is an ethylene-based polymer.8. An article comprising the blend of .9. A method of making a compatibilized blend claim 1 , the method comprising mixing a thermoplastic olefin polymer claim 1 , a thermoplastic polyurethane and a phenolic resole resin and crosslinking the thermoplastic polyurethane with the phenolic resole resin with ...

Halogen-Free, Flame Retardant TPU Composite

Halogen-free TPU compositions comprise in weight percent based on the weight of the composition: A. 1 to 99% thermoplastic polyurethane (TPU), B. 1 to 50% tris(2-butoxyethyl)phosphate (TBEP), C. 1 to 70% metal hydrate, and D. 1 to 70% organic phosphate ester other than tris(2-butoxyethyl)phosphate. These compositions exhibit better smoke suppression as compared with conventional organic phosphate flame retardant TPU compositions such as those based on resorcinol bis(diphenyl phosphate) (RDP) and bisphenol-A bis(diphenyl phosphate) (BPADP) in the absence of TBEP. 1. A halogen-free TPU composition comprising in weight percent based on the weight of the composition:A. 1 to 99% thermoplastic polyurethane (TPU),B. 1 to 50% tris(2-butoxyethyl)phosphate (TBEP),C. 1 to 70% metal hydrate, andD. 1 to 70% organic phosphate ester other than tris(2-butoxyethyl)phosphate;wherein the total percentages of all components are 100%.2. The composition of in which the TPU is at least one of polyether-based and polyester-based polyurethane and is present in an amount of 15 to 80 wt %.3. The composition of in which the metal hydrate is at least one of aluminum trihydroxide (ATH) and magnesium hydroxide and is present in an amount of 10 to 60 wt %.4. The composition of in which the organic phosphate ester is at least one of resorcinol bis(diphenyl phosphate) (RDP) and bisphenol-A bis(diphenyl phosphate) (BPADP) and is present in an amount of 5 to 60 wt %.5. The composition of in which the TBEP is present in an amount of 2 to 30 wt %.6. The composition of further comprising at least one of an anti-dripping agent claim 5 , an antioxidant claim 5 , UV-stabilizer claim 5 , processing aid and filler.7. The composition of in which the anti-dripping agent is triglycidyl isocyanurate and is present in an amount of 0.1 to 10 wt %.8. The composition of further comprising at least one of ethylene vinyl acetate (EVA) claim 7 , polyethylene claim 7 , polypropylene claim 7 , ethylene- or propylene ...

IMAGING DEVICE HAVING LIGHT FIELD SENSOR

A method of imaging a target object with an imaging reader. The method includes the following: (1) detecting light from the target object through a lens arrangement with an image sensor to generate light-field data; (2) generating a stream of image data including image data representing an expected in-focus image of the target object, and (3) processing the expected in-focus image of the target object to decode a barcode on the target object. The image sensor includes an array of photosensitive elements and an array of microlenses that overlays the array of photosensitive elements located at a focus plane of the microlens. 1. An apparatus comprising:an illumination source for providing illumination directed toward a target object;an image sensor for generating light-field data, wherein the image sensor comprises (1) an array of photosensitive elements and (2) an array of microlenses that overlays the array of photosensitive elements with a uniform spacing, wherein a microlens covers multiple photosensitive elements each receiving light through the microlens to function as a sub-pixel;an image processing unit (IPU) operatively connected to the image sensor to receive the light-field data from the image sensor, the IPU being operative to generate a stream of image data including image data representing an expected in-focus image of the target object; anda controller operatively connected to the IPU to process the stream of image data received from the IPU.2. The apparatus of claim 1 , wherein the IPU is configured for:selecting a set of predetermined focus planes; andconstructing a set of images of the target object from the light-field data, wherein each image in the set of images is constructed from the light-field data using one of the predetermined focus planes as a corresponding focus plane.3. The apparatus of claim 2 , further comprising:a lens arrangement positioned in front of the image sensor; andwherein each predetermined focus plane is titled with respect ...

Method For Increasing The Activity Of Lysosomal Enzymes

Method for enhancing in a mammalian cell the activity of an enzyme associated with Gaucher Disease by administering a competitive inhibitor of glucocerebrosidase in an amount effective to enhance the activity of the enzyme. Preferred compounds for use in the method are imino sugars and related compounds. In particular, C8-12-alkyl derivatives of N-alkyl-deoxynojirimycin, isofagomine compounds, and calystegine compounds are effective to enhance glucocerebrosidase activity. 1. Method of treating Hurler-Scheie disease in a subject in need thereof , comprising administering to the subject an effective amount of a competitive inhibitor of α-L-iduronidase.2. The method of claim 1 , wherein the competitive inhibitor is 1-deoxyiduronojirimycin.3. The method of claim 1 , wherein the competitive inhibitor is 2-carboxy-3 claim 1 ,4 claim 1 ,5-trideoxypiperidine.4. A method for increasing in a mammalian cell the activity of α-L-iduronidase claim 1 , which method comprises contacting the cell with a reversible competitive inhibitor of the α-L-iduronidase in an amount effective to increase α-L-iduronidase activity.5. The method of claim 4 , wherein the competitive inhibitor is 1-deoxyiduronojirimycin.6. The method of claim 4 , wherein the competitive inhibitor is 2-carboxy-3 claim 4 ,4 claim 4 ,5-trideoxypiperidine. This application is a continuation of application Ser. No. 12/890,014, filed on Sep. 24, 2010, which is a continuation of application Ser. No. 11/528,903, filed on Sep. 27, 2006, now U.S. Pat. No. 7,812,033, which is a continuation of application Ser. No. 10/989,258, filed on Nov. 16, 2004, now U.S. Pat. No. 7,141,582, which is a continuation of application Ser. No. 10/304,395, filed on Nov. 26, 2002, now U.S. Pat. No. 6,916,829, which is a continuation of application Ser. No. 09/948,348, filed on Sep. 7, 2001, now U.S. Pat. No. 6,599,919, which is a continuation of application Ser. No. 09/604,053, filed on Jun. 26, 2000, now U.S. Pat. No. 6,583,158, which is a ...

IMAGING DEVICE HAVING LIGHT FIELD IMAGE SENSOR

A method of imaging a target object with an imaging reader. The method includes the following: (1) detecting light from the target object through a lens arrangement with an image sensor to generate light-field data; (2) generating a stream of image data including image data representing an expected in-focus image of the target object, and (3) processing the expected in-focus image of the target object to decode a barcode on the target object. The image sensor includes an array of photosensitive elements and an array of microlenses that overlays the array of photosensitive elements located at a focus plane of the microlens. 1. An apparatus comprising:an image sensor for generating light-field data, wherein the image sensor comprises (1) an array of photosensitive elements and (2) an array of microlenses that overlays the array of photosensitive elements with a uniform spacing, wherein a microlens covers multiple photosensitive elements each receiving light through the microlens to function as a sub-pixel;an image processing unit (IPU) operatively connected to the image sensor to receive the light-field data from the image sensor, the IPU being operative to generate a stream of image data including image data representing an expected in-focus image of a target object; anda controller operatively connected to the IPU to process the stream of image data received from the IPU.2. The apparatus of claim 1 , wherein the IPU is configured for:selecting a set of predetermined focus planes; andconstructing a set of images of the target object from the light-field data, wherein each image in the set of images is constructed from the light-field data using one of the predetermined focus planes as a corresponding focus plane.3. The apparatus of claim 2 , further comprising:a lens arrangement positioned in front of the image sensor; andwherein each predetermined focus plane is titled with respect an optical axis of the lens arrangement.4. The apparatus of claim 2 , wherein the IPU ...

COMMUNICATION METHOD AND COMMUNICATIONS APPARATUS

Embodiments of this application provide a communication method and a communications apparatus. The communication method includes: when a radio bearer RB needs to be established between a network device and a terminal device, the network device includes a first node and a second node, and functional entities corresponding to the RB include one PDCP entity and more than two RLC entities corresponding to the PDCP entity. The method includes: determining, by the first node, configuration information, where the configuration information is used to instruct the second node to establish N tunnels, the tunnel is used to transmit PDCP data or RLC data between the first node and the second node, and N is an integer greater than or equal to 2; and transmitting, by the first node, the configuration information to the second node. 1. A communication method , wherein when a radio bearer (RB) is established between a network device and a terminal device , the network device comprises a first node and a second node , and functional entities corresponding to the RB comprise one packet data convergence protocol (PDCP) entity and more than two radio link control (RLC) entities corresponding to the PDCP entity , wherein the method comprises:receiving, by the terminal device, second status indication information transmitted by the first node, wherein the second status indication information indicates whether each of more than two RLC entities corresponding to the PDCP entity is activated, or indicates whether an RLC entity established on the first node is activated; orreceiving, by the terminal device, third status indication information transmitted by the second node, wherein the third status indication information indicates whether each of more than two RLC entities corresponding to the PDCP entity is activated, or indicates whether an RLC entity established on the second node is activated; andtransmitting, by the terminal device based on at least one of the second status indication ...

COMMUNICATION METHOD, COMMUNICATIONS APPARATUS, AND SYSTEM

This application provides a communication method, a communications apparatus, and a system, to reduce a transmission delay of an emergency service. The method may include receiving an uplink grant. The method may also include determining, based on a time-domain position of an uplink grant resource indicated by the uplink grant, a first uplink grant resource used to transmit first service data. Furthermore, the method may include transmitting the first service data on the first uplink grant resource. 1. A communication method , comprising:receiving one or more uplink grants;determining, based on a time-domain position of one or more uplink grant resources indicated by the one or more uplink grants and from the one or more uplink grant resources, a first uplink grant resource used to transmit first service data; andtransmitting the first service data on the first uplink grant resource.2. The method according to claim 1 , wherein the determining the first uplink grant resource comprises:determining first remaining time of the one or more uplink grant resources based on a time-domain end position of the one or more uplink grant resources indicated by the one or more uplink grants, wherein the first remaining time of each of the one or more uplink grant resources is a time interval between a time-domain end position of the each uplink grant resource and a timeout moment for the first service data; anddetermining the first uplink grant resource from the one or more uplink grant resources, wherein the first remaining time of the first uplink grant resource is greater than or equal to a preconfigured delay threshold.3. The method according to claim 2 , wherein the method further comprises:receiving indication information of the preconfigured delay threshold.4. The method according to claim 1 , wherein the one or more uplink grant resources comprises a plurality of uplink grant resources claim 1 , and the first uplink grant resource is a resource at a foremost time-domain ...

SYSTEM, METHOD AND NETWORK NODE FOR GENERATING AT LEAST ONE CLASSIFICATION BASED ON MACHINE LEARNING TECHNIQUES

The disclosure relates to a system, method, and network node for generating at least one classification based on multiple data sources. The system comprises at least one layer comprising one or more supervised neural networks (SNN); at least one layer comprising one or more unsupervised neural networks (USNN); and at least one normalization layer. Each of the layers has inputs and outputs, the inputs of a first layer being operative to receive data from the data sources, the inputs of a layer other than the first layer being communicatively connected to the outputs of a previous layer, the outputs of a layer other than a last layer being communicatively connected to inputs of a following layer, the last layer having at least one output, and the at least one normalization layer being operative to normalize the outputs from the previous layer into normalized inputs for the following layer. 2. The system of claim 1 , wherein the system comprises at least two layers of SNNs.3. The system of claim 1 , wherein the system comprises at least two layers of USNNs.4. The system of claim 1 , wherein the system comprises at least two normalization layers.5. The system of claim 1 , wherein the system comprises three layers claim 1 , the first layer comprising SNNs claim 1 , the second layer being a normalization layer and the last layer comprising USNNs and one SNN.6. The system of claim 5 , wherein the SNN of the last layer generates the at least one classification using as inputs the outputs of the USNNs.7. The system of claim 1 , wherein each SNN and each USNN has multiple inputs and each SNN and each USNN has a single output.8. The system of claim 1 , wherein each SNN and each USNN has multiple inputs and at least one of the SNNs and USNNs has multiple outputs.9. The system of claim 1 , wherein the normalization layer normalizes the outputs from the previous layer into normalized inputs for the following layer by matching and replacing the outputs from the previous layer with ...

Method and Apparatus for Controlling Terminal, and Terminal

The present invention provides a method and an apparatus for controlling a terminal, and a terminal. The method includes: receiving a terminal identity sent by a terminal; acquiring, according to the terminal identity, time control information that corresponds to an application identity of an application on the terminal; and sending the time control information to the terminal, so that the terminal controls, according to the time control information, use time of the application that corresponds to the application identity. 1. A method for controlling a terminal , the method comprising:receiving a terminal identity sent by a terminal;acquiring, according to the terminal identity, time control information that corresponds to an application identity of an application on the terminal; andsending the time control information to the terminal, so that the terminal controls, according to the time control information, use time of the application that corresponds to the application identity.2. The method for controlling a terminal according to claim 1 , wherein acquiring the time control information comprises:acquiring, according to the terminal identity, the application identity that corresponds to the terminal identity, wherein the application identity is an identity of an application on the terminal; andacquiring, according to the application identity, time control information that corresponds to the application identity.3. The method for controlling a terminal according to claim 1 , wherein the time control information comprises use time information of the application claim 1 , so that the terminal controls the use time of the application according to the use time information.4. The method for controlling a terminal according to claim 3 , wherein the time control information further comprises access time information of data to be accessed by the application claim 3 , so that the terminal controls claim 3 , according to the use time information of the application and the ...

COMMUNICATION METHOD AND COMMUNICATIONS APPARATUS

This application provides a communication method and a communications apparatus. The method includes: receiving, by a terminal device, a configuration message from a network device, where the configuration message is used to configure a plurality of uplink BWPs and a plurality of downlink BWPs; determining, by the terminal device, a first BWP in the plurality of uplink BWPs, where the first BWP is used to transmit feedback information of downlink information that is on a second BWP, and the second BWP is any one of the plurality of downlink BWPs; receiving, by the terminal device, the downlink information on the second BWP; and sending, by the terminal device, the feedback information of the downlink information by using the first BWP, so that a BWP on which the feedback information is sent can be determined in a scenario in which a plurality of BWPs are activated. 1. A communication method , comprising:receiving, by a terminal device, a configuration message from a network device, wherein the configuration message configures a plurality of uplink bandwidth parts (BWPs) and a plurality of downlink BWPs;determining, by the terminal device, a first BWP in the plurality of uplink BWPs, wherein the first BWP is to be used to transmit feedback information of downlink information that is on a second BWP, and wherein the second BWP is a BWP in the plurality of downlink BWPs;receiving, by the terminal device, the downlink information on the second BWP; andsending, by the terminal device, the feedback information of the downlink information on the first BWP.2. The method according to claim 1 , further comprising:receiving, by the terminal device, indication information from the network device, wherein the indication information indicates the first BWP; andwherein determining the first BWP in the plurality of uplink BWPs comprises:determining, by the terminal device, the first BWP based on the indication information.3. The method according to claim 2 , wherein the indication ...

COMBINATION THERAPY FOR TREATING PROTEIN DEFICIENCY DISORDERS

This application provides methods of improving protein replacement therapy by combining protein replacement therapy with active site-specific chaperones (ASSC) to increase the stability and efficiency of the protein being administered. The application further provides stable compositions comprising the purified protein and an ASSC, and methods of treatment by administering the compositions. 120-. (canceled)21: A stable pharmaceutical composition formulated for parenteral administration to a human and comprising a purified recombinant human wild-type α-galactosidase A and 1-deoxygalactonojirimycin in a pharmaceutically acceptable carrier.22: The stable pharmaceutical composition according to claim 21 , which is formulated for intravenous claim 21 , subcutaneous claim 21 , or intraperitoneal administration.23: The stable pharmaceutical composition according to claim 21 , further comprising:a buffer selected from the group consisting of a citrate buffer, a phosphate buffer, an acetate buffer, and a bicarbonate buffer.24: A method of treating Fabry disease claim 21 , the method comprising:{'claim-ref': {'@idref': 'CLM-00021', 'claim 21'}, 'administering the stable pharmaceutical composition according to to a human patient in need thereof.'} This application is a divisional of U.S. application Ser. No. 11/317,404, filed on Dec. 23, 2005 (pending), which is a continuation of U.S. application Ser. No. 10/771,236, filed on Feb. 2, 2004 (abandoned), which claims priority benefit from U.S. Provisional Application Ser. No. 60/444,136, filed Jan. 31, 2003 (abandoned), each of which is incorporated by reference herein in its entirety.This application provides methods of improving protein replacement therapy by combining protein replacement therapy with active site-specific chaperones (ASSC) to increase the stability and efficiency of the protein being administered. The application further provides compositions comprising the purified protein and an ASSC.Proteins are synthesized ...

Method of enhancing lysosomal alpha-Galactosidase A

A method of enhancing the activity of lysosomal α-Galactosidase A (α-Gal A) in mammalian cells and for treatment of Fabry disease by administration of 1-deoxy-galactonojirimycin and related compounds. 19-. (canceled)11. The method of claim 10 , wherein Ris H claim 10 , Ris OH claim 10 , Ris H and Ris H.12. The method of claim 10 , wherein Ris H claim 10 , Ris OH claim 10 , Ris H and Ris OH.13. The method of claim 10 , wherein Ris H claim 10 , Ris H claim 10 , Ris OH and Ris OH.14. The method of claim 10 , wherein Ris CH claim 10 , Ris OH claim 10 , Ris H and Ris H.15. The method of claim 10 , wherein Ris CH claim 10 , Ris OH claim 10 , Ris H and Ris OH.16. The method of wherein Ris CH claim 10 , Ris H claim 10 , Ris OH and Ris OH.18. The method of claim 17 , wherein Ris H claim 17 , Ris OH claim 17 , Ris H and Ris H.19. The method of claim 17 , wherein Ris H claim 17 , Ris OH claim 17 , Ris H and Ris OH.20. The method of claim 17 , wherein Ris H claim 17 , Ris H claim 17 , Ris OH and Ris OH.21. The method of claim 17 , wherein Ris CH claim 17 , Ris OH claim 17 , Ris H and Ris H.22. The method of claim 17 , wherein Ris CH claim 17 , Ris OH claim 17 , Ris H and Ris OH.23. The method of wherein Ris CH claim 17 , Ris H claim 17 , Ris OH and Ris OH. This application claims priority from U.S. patent application Ser. No. 09/927,285, filed on Aug. 10, 2001, which claims priority from U.S. patent application Ser. No. 09/087,804, now U.S. Pat. No. 6,274,597, which is hereby incorporated by reference.This invention relates to a method of enhancing the activity of lysosomal .alpha.-Galactosidase A α-Gal A) in mammalian cells and for treatment of glycosphingolipid storage diseases, in particular Fabry disease, by administration of 1-deoxy-galactonojirimycin and related compounds.Fabry disease (1) is a glycosphingolipid lysosomal storage disease caused by an X-linked inherited deficiency of lysosomal α-galactosidase A α-Gal A), an enzyme responsible for the hydrolysis of terminal ...

BANDWIDTH PART PROCESSING METHOD AND APPARATUS

A bandwidth part processing method and apparatus is provided. The method includes: when an inactivity timer corresponding to an active first bandwidth part BWP expires, determining whether a carrier in which the first BWP is located includes a second BWP in an active state; and when the carrier includes the second BWP in the active state, deactivating the first BWP. According to this method, an unnecessary BWP switch procedure can be avoided. 1. An apparatus , comprising:a memory, configured to store computer programming; andat least one processor, configured to execute the computer programming stored in the memory, to enable a terminal to perform operations comprising:when an inactivity timer corresponding to an active first bandwidth part (BWP) expires, determining whether a carrier in which the first BWP is located comprises a second BWP in an active state; andwhen the carrier comprises the second BWP in the active state, deactivating the first BWP.2. The apparatus according to claim 1 , wherein the second BWP is a default BWP or an initial BWP.3. The apparatus according to claim 1 , wherein the second BWP is a non-default BWP or a non-initial BWP.4. The apparatus according to claim 3 , wherein when the carrier comprises the second BWP in the active state claim 3 , the operations further comprises:skipping activating a default BWP or an initial BWP in the carrier.5. The apparatus according to claim 1 , wherein when the carrier does not comprise the second BWP in the active state claim 1 , the operations further comprises:activating the default BWP or the initial BWP in the carrier.6. The apparatus according to claim 5 , wherein when there are at least two default BWPs in the carrier claim 5 ,the activating the default BWP in the carrier comprises:activating all BWPs comprised in the at least two default BWPs; oractivating a BWP that is comprised in the at least two default BWPs and that meets a preset rule.7. The apparatus according to claim 6 , wherein the ...

Sidelink Transmission Resource Configuration Method And Apparatus

This application provides an example sidelink transmission resource configuration method. Each piece of sidelink data corresponds to one transmission requirement. After obtaining a first data, a terminal device determines a transmission feature of the first resource, and determines, depending on whether reliability of the first resource meets a reliability requirement of the first data, whether to send the first data by using the first resource. 1. A sidelink transmission resource configuration method , comprising:obtaining a transmission requirement of first data, wherein the first data needs to be transmitted on a sidelink; andwhen a first resource does not meet the transmission requirement of the first data, sending request information to a network device, wherein the request information is used to request to configure a second resource, wherein the first resource is a resource that is configured by using a broadcast message and that is used to transmit data on the sidelink, and wherein the second resource is a resource that is configured by using a unicast message and that is used to transmit data on the sidelink.2. The method according to claim 1 , wherein: receiving configuration information from the network device, wherein the configuration information is used to configure a correspondence between a service type of data and a channel busy ratio (CBR) threshold; and', 'determining, based on the correspondence and a service type of the first data, a CBR threshold corresponding to the first data, wherein the CBR threshold corresponding to the first data is the transmission requirement of the first data, and wherein, 'the obtaining a transmission requirement of first data comprises 'when a CBR of the first resource does not meet the CBR threshold corresponding to the first data, determining that the first resource does not meet the transmission requirement of the first data.', 'the method further comprises3. The method according to claim 1 , wherein the obtaining ...

Communication Method and Related Device

A communication method and a related apparatus for data transmission in vehicle-to-everything (V2X) communication, the apparatus including at least one processor and a non-transitory computer-readable memory storing a program to be executed by the at least one processor, the program including instructions for obtaining a first parameter value of an uplink, obtaining a second parameter value of a sidelink, and transmitting, according to a comparison between the first parameter value and the second parameter value, at least one of an uplink media access control protocol data unit or a sidelink media access control protocol data unit, where the uplink is a wireless communications link from the apparatus to a network device, and where the sidelink is a wireless direct transmission link between the apparatus and another terminal device.

V2X COMMUNICATION METHOD AND V2X COMMUNICATIONS APPARATUS

This application provides an example vehicle to everything (V2X) communication method and an example V2X communications apparatus. According to the method, different transmission parameters can be selected for data packets corresponding to different services, ProSe per-packet priority (PPPP) of services, ProSe per-packet reliability (PPPR) of services, or quality of service flow identifiers (QFIs) based on service information of the data packets. 1. A method , comprising:obtaining a first correspondence between service information and a first transmission parameter, wherein the service information comprises any one or more of the following: a service identifier, a ProSe per-packet priority (PPPP) of a service, a ProSe per-packet reliability (PPPR) of a service, or a quality of service flow identifier (QFI):obtaining a transmission resource and a second transmission parameter corresponding to the transmission resource, wherein the second transmission parameter has an association relationship with the first transmission parameter, or the second transmission parameter belongs to the first transmission parameter; andallocating, based on the first correspondence and the second transmission parameter corresponding to the transmission resource, the transmission resource to a to-be-transmitted data packet corresponding to the service information.2. The method according to claim 1 , wherein the first transmission parameter comprises any one or more of the following parameters: information about an allowed subcarrier spacing (SCS) claim 1 , a maximum physical sidelink shared channel (PSSCH) duration claim 1 , information about an allowed cell claim 1 , information about an allowed frequency claim 1 , information about a minimum block error rate claim 1 , information about an allowed first-type resource claim 1 , information about an allowed second-type resource claim 1 , information about an allowed modulation and coding scheme (MCS) table claim 1 , or information about an ...

COMMUNICATION METHOD AND RELATED DEVICE

A communication method for data transmission in the internet of vehicles V2X and a related device. The method includes a first terminal device that receives first information from a first radio access network device, where the first information includes service information of a service of the first terminal device and a resource configuration mode on a sidelink, and there is a correspondence between the service information and the resource configuration mode on the sidelink. The first terminal device transmits, based on the correspondence, data corresponding to the service information on a sidelink transmission resource configured based on the resource configuration mode. The service information may be reliability information. 1. A communication method , applied to a first terminal device , the method comprising:receiving, by the first terminal device, first information from a first radio access network device, wherein the first information comprises service information of a service of the first terminal device and a resource configuration mode on a sidelink, and there is a correspondence between the service information and the resource configuration mode on the sidelink; andtransmitting, by the first terminal device based on the correspondence, data corresponding to the service information on a sidelink transmission resource configured based on the resource configuration mode, whereinthe sidelink is a wireless communications link between the first terminal device and a second terminal device.2. The method according to claim 1 , wherein the transmitting claim 1 , by the first terminal device based on the correspondence claim 1 , of the data corresponding to the service information on a sidelink transmission resource configured based on the resource configuration mode comprises any one of the following:when the resource configuration mode on the sidelink is a first resource configuration mode, transmitting, by the first terminal device based on the correspondence, ...

METHODS FOR TREATING OBSTRUCTIVE SLEEP APNEA

The present invention relates to methods for treating obstructive sleep apnea (OSA), alleviating a negative OSA symptom, reducing snoring, or improving quality of life in a subject, comprising administering to the subject an effective amount of a pharmaceutical composition comprising pyridostigmine before sleep. Also provided are related medicaments as well as methods for preparing the medicaments. 1. A method for treating obstructive sleep apnea (OSA) in a subject in need thereof , comprising administering to the subject an effective amount of a pharmaceutical composition comprising pyridostigmine before sleep.2. The method of claim 1 , wherein apnea claim 1 , hypopnea claim 1 , snoring claim 1 , or low oxygen saturation events in the subject is reduced.3. The method of claim 1 , wherein sleep quality or daytime quality of life of the subject is improved.4. The method of claim 1 , wherein the effective amount of the pharmaceutical composition to is selected to provide a target serum concentration of pyridostigmine in the subject in the range of 2-150 ng/ml for at least one hour.5. The method of claim 4 , wherein the target serum concentration is in the range of 3-60 ng/ml.6. The method of claim 4 , wherein the target serum concentration is in the range of 3-45 ng/ml.7. The method of claim 4 , wherein the target serum concentration is maintained for at least three hours.8. The method of claim 1 , wherein the pharmaceutical composition comprises 30-360 mg pyridostigmine.9. The method of claim 1 , wherein the pharmaceutical composition is administered to the subject within 2 hours before sleep.10. The method of claim 1 , wherein the pharmaceutical composition is administered to the subject in a single dose.11. The method of claim 1 , wherein the pharmaceutical composition further comprises a pharmaceutically acceptable carrier or diluent.12. The method of claim 1 , wherein the pharmaceutical composition is administered to the subject in an oral dosage form.13. The ...

Data transmission method, radio access network device, and terminal device

The embodiments of this application provide a data transmission method, including: receiving, by a first radio access network device, traffic model information of a first terminal device that is sent by the first terminal device; sending, by the first radio access network device, the traffic model information of the first terminal device to a second radio access network device; receiving, by the first radio access network device, first resource configuration information sent by the second radio access network device; and sending, by the first radio access network device, a configuration message to the first terminal device.

DATA TRANSMISSION METHOD AND APPARATUS

A data transmission method includes obtaining, by a first communication apparatus, a data packet, a first quality of service (QoS) parameter and a second QoS parameter, mapping, by the first communication apparatus, the data packet to a data radio bearer (DRB) or a radio link control (RLC) layer entity based on the first QoS parameter and the second QoS parameter, and sending the data packet to a second communication apparatus. The first QOS parameter and the second QOS parameter corresponding to the data packet. 1. A data transmission method , wherein the method comprises:obtaining, by a first communication apparatus, a data packet, a first quality of service (QoS) parameter and a second QoS parameter, wherein the first QOS parameter and the second QOS parameter correspond to the data packet;mapping, by the first communication apparatus, the data packet to a data radio bearer (DRB) or a radio link control (RLC) layer entity based on the first QoS parameter and the second QoS parameter, andsending the data packet to a second communication apparatus.2. The method according to claim 1 , whereinthe first QoS parameter is included in the data packet, orinformation that is useable to indicate the first QoS parameter is included carried in the data packet.3. The method according to claim 1 , wherein the first communication apparatus is a terminal device claim 1 , and the first QoS parameter is allocated to the data packet by an application layer of the first communication apparatus.4. The method according to claim 1 , wherein the first communication apparatus is a network device claim 1 , andthe obtaining, by the first communication apparatus, the data packet, the first QoS parameter and the second QOS parameter comprises:receiving, by the first communication apparatus, a GTP-U data packet from a core network device, wherein the GTP-U data packet comprises the data packet and indication information, and the indication information is useable to indicate the first QoS ...

COMMUNICATION METHOD, RESOURCE ALLOCATION METHOD, AND APPARATUS

A first terminal obtains a first transmission resource that is sent by an access network device and that is used by the first terminal to send data on a sidelink, where the sidelink is a wireless communication link between the first terminal and a second terminal, and the first transmission resource is a resource of an unlicensed spectrum. The first terminal performs a channel access procedure on the unlicensed spectrum. The first terminal sends first information to the access network device when the first terminal determines that a failure occurs in the channel access procedure performed on the unlicensed spectrum, where the first information is used to request to allocate a second transmission resource to the sidelink of the unlicensed spectrum. 1. A communication method comprising:receiving, by a first terminal, indication information of a first transmission resource to be used by the first terminal to send data on a sidelink from an access network device, wherein the sidelink is a wireless communication link between the first terminal and a second terminal, and wherein the first transmission resource is a resource of an unlicensed spectrum;performing, by the first terminal, a channel access procedure on the unlicensed spectrum; andsending, by the first terminal, first information to the access network device when a failure occurs in the channel access procedure performed on the unlicensed spectrum, wherein the first information is to request to allocate a second transmission resource to the sidelink of the unlicensed spectrum.2. The communication method according to claim 1 , wherein the second transmission resource is associated with information about the unlicensed spectrum; orwherein the second transmission resource is associated with information about a channel on which the failure occurs in the channel access procedure and the channel is one of one or more channels associated with the unlicensed spectrum.3. The communication method according to claim 1 , ...

COMMUNICATION METHOD AND APPARATUS, AND COMPUTER STORAGE MEDIUM

Embodiments of this application provide a communication method and apparatus, and a computer storage medium, to reduce communication latency between a terminal and a base station, and improve a capability of adapting to a latency-sensitive scenario. The method provided in this application includes a terminal that receives at least one uplink configuration and at least one random access configuration from a network device. The uplink configuration is used to indicate a parameter for sending uplink data, and the random access configuration is used to indicate a parameter for sending a preamble. The at least one uplink configuration includes a first uplink configuration, the at least one random access configuration includes a first random access configuration, and there is a correspondence between the first uplink configuration and the first random access configuration. 1. A communication method , comprising:receiving, by a terminal from a network device, at least one uplink configuration is used to indicate a parameter for sending uplink data, wherein the at least one uplink configuration comprises a first uplink configuration;receiving, by the terminal from the network device, at least one random access configuration used to indicate a parameter for sending a preamble, wherein the at least one random access configuration comprises a first random access configuration, and wherein there is a correspondence between the first uplink configuration and the first random access configuration; andbased on the correspondence between the first uplink configuration and the first random access configuration, sending, by the terminal, the uplink data to the network device using the first uplink configuration, and sending, by the terminal, the preamble to the network device using the first random access configuration.2. The method according to claim 1 , further comprising:receiving, by the terminal from the network device, a first correspondence between the at least one uplink ...

METHOD AND DEVICE FOR EXAMINING QUALITY OF DUMMY PATTERN INSERTION PROGRAM USED IN CIRCUIT LAYOUT DESIGN

A method for examining quality of a dummy pattern insertion program may be implemented using a device that includes hardware. The method may include using the dummy pattern insertion program to generate a dummy-based circuit layout, a first dummy-inserted circuit layout, and a second dummy-inserted circuit layout. The method may further include determining whether the dummy-based circuit layout complies with a set of circuit layout design rules. The method may further include checking whether the first dummy-inserted circuit layout complies with at least one of a set of dummy pattern check rules and a set of pattern density rules. The method may further include examining whether the second dummy-inserted circuit layout complies with at least one of the set of circuit layout design rules, the set of dummy pattern check rules, and the set of pattern density rules. 1. A method for examining quality of a dummy pattern insertion program , the method being implemented using a device that includes hardware , the method comprising:using the dummy pattern insertion program to generate a dummy-based circuit layout;determining whether the dummy-based circuit layout complies with a set of circuit layout design rules;using the dummy pattern insertion program to generate a first dummy-inserted circuit layout;checking whether the first dummy-inserted circuit layout complies with at least one of a set of dummy pattern check rules and a set of pattern density rules;using the dummy pattern insertion program to generate a second dummy-inserted circuit layout; andexamining whether the second dummy-inserted circuit layout complies with at least one of the set of circuit layout design rules, the set of dummy pattern check rules, and the set of pattern density rules.2. The method of claim 1 , comprising: checking whether the first dummy-inserted circuit layout complies with both of the set of dummy pattern check rules and the set of pattern density rules.3. The method of claim 1 , ...

Data Transmission Method and Apparatus

A first terminal device has first data to be transmitted on a sidelink and has second data to be transmitted on an uplink. The first terminal device performs medium access control MAC protocol data unit PDU assembly on the first data or does not perform MAC PDU assembly on the first data based on a result of comparison between a transmission priority of the first data and a transmission priority of the second data. 112.-. (canceled)13. A method , comprising:obtaining, by a first terminal device, a quantity of sending times of sending a medium access control (MAC) protocol data unit (PDU) corresponding to first data, wherein the first data is to be sent by the first terminal device to a second terminal device on a sidelink, and the sidelink is a direct wireless communication link between the first terminal device and the second terminal device; andsending, by the first terminal device using a third transmission resource, the MAC PDU based on the quantity of sending times, wherein the third transmission resource is any transmission resource in periodic resources of the first terminal device.14. The method according to claim 13 , wherein obtaining claim 13 , by the first terminal device claim 13 , the quantity of sending times of sending the MAC PDU corresponding to the first data comprises:determining, by the first terminal device, the quantity of sending times based on a quality of service parameter corresponding to the MAC PDU, and based on a correspondence between the quantity of sending times and the quality of service parameter corresponding to the MAC PDU.15. The method according to claim 13 , further comprising:sending, by the first terminal device, control information to the second terminal device, wherein the control information comprises a new data indicator (NDI), a redundancy version (RV) identifier, and a time-frequency resource indicator, and the time-frequency resource indicator indicates a time-frequency resource location of the third transmission ...

COMMUNICATIONS METHOD AND APPARATUS

A communications method that meets QoS requirements of services of different communication types, including: an application layer entity of a first terminal device delivers communication type information and a target side identifier to a control layer entity of the first terminal device; the control layer entity of the first terminal device establishes, based on the communication type information, a radio bearer group that is of a sidelink and that corresponds to a communication type, where the radio bearer group of the sidelink corresponds to the target side identifier. 118-. (canceled)19. A communication method , wherein the method comprises:sending, by an application layer entity of a first terminal device, communication type information and a target side identifier to a control layer entity of the first terminal device, wherein the communication type information comprises or indicates a communication type of a communication to be performed by the first terminal device, the communication type is unicast communication or multicast communication, and the target side identifier identifies the communication of the communication type; andestablishing, by the control layer entity of the first terminal device based on the communication type information, a radio bearer group of a sidelink for the communication of the communication type, wherein the radio bearer group of the sidelink corresponds to the target side identifier, and the sidelink is a wireless communications link between the first terminal device and a second terminal device.20. The method according to claim 19 , whereinconfiguration information of the radio bearer group of the sidelink is prestored in the first terminal device; orthe method further comprises: receiving, by the first terminal device, configuration information of the radio bearer group of the sidelink sent by a radio access network device.21. The method according to claim 19 , wherein the method further comprises:sending, by the control layer ...

COMMUNICATION METHOD AND DEVICE

Embodiments of this application provide a communication method and a related device. The method which is implemented by a terminal device includes: receiving a configuration message, where the configuration message indicates the terminal device to establish at least three radio link control (RLC) entities on a first bearer; establishing the at least three RLC entities on the first bearer based on the configuration message; and performing data transmission through at least one RLC entity on the first bearer. According to the application, data transmission reliability is improved and a data transmission latency is reduced. 1. A communication method , applied to a terminal device , the method comprising:receiving a configuration message, wherein the configuration message indicates the terminal device to establish at least three radio link control (RLC) entities on a first bearer;establishing the at least three RLC entities on the first bearer based on the configuration message; andperforming data transmission through at least one RLC entity on the first bearer.2. The method according to claim 1 , wherein the performing the data transmission through the at least one RLC entity on the first bearer comprises:generating a first data packet; andperforming duplicate transmission on the first data packet through at least two RLC entities on the first bearer.3. The method according to claim 2 , further comprising:indicating, to an RLC entity in the at least two RLC entities, that the first data packet is a duplicated data packet.4. The method according to claim 1 , further comprising:receiving a first instruction from an access network device, wherein the first instruction comprises a bearer status field, the bearer status field comprises at least one bit, the bearer status field corresponds to a bearer configured with a duplicate transmission function, each bit in the bearer status field corresponds to one secondary RLC entity on the bearer, and the bit is used to indicate to ...

TRANSMISSION METHOD AND APPARATUS

A method includes: a first terminal device obtains information about a first sidelink transmission unit, the first terminal device transmits the data packet via the first SL transmission unit through a hybrid automatic repeat request process corresponding to a unicast connection or a groupcast communication group, when the data packet fails to be transmitted, the first terminal device obtains information about a second SL transmission unit, retransmits the data packet via the second SL transmission unit. 1. A transmission method , applied to a first terminal device and comprising:obtaining, by the first terminal device, information about a first sidelink (SL) transmission unit, wherein the first SL transmission unit is used on an SL for sending a to-be-transmitted data packet of a unicast connection or a groupcast communication group, and the SL is a wireless communication link between the first terminal device and a second terminal device;transmitting, by the first terminal device, the data packet by using the first SL transmission unit through a hybrid automatic repeat request (HARQ) process corresponding to the unicast connection or the groupcast communication group;when the data packet fails to be transmitted, obtaining, by the first terminal device, information about a second SL transmission unit; andretransmitting, by the first terminal device, the data packet by using the second SL transmission unit.2. The method according to claim 1 , wherein the method further comprises:receiving, by the first terminal device, an HARQ feedback result of the data packet from the second terminal device; and;when the HARQ feedback result is acknowledgment information ACK, forwarding, by the first terminal device, the ACK to a resource scheduling device; or,when the HARQ feedback result is negative information NACK or when the first terminal device does not receive the HARQ feedback from the second terminal device, sending, by the first terminal device, the NACK to the resource ...

NETWORK ACCESS METHOD AND APPARATUS

A network access method and an apparatus relate to the field of communications technologies, and are used to support an industrial terminal in accessing a network when an architecture in which a control node sinks is used in a communications network. The method includes: An access network device sends an access list of a cell, where the access list of the cell includes at least one MAC address or group identifier. The access network device receives a message sent by a terminal, where the message includes a MAC address or a group identifier of the terminal. The access network device determines, depending on whether the MAC address or the group identifier of the terminal exists in the access list of the cell, whether the terminal can access the cell. This application is applicable to a process in which a terminal accesses a network. 1. A network access method , wherein the method comprises:sending, by an access network device, an access list of a cell, wherein the access list of the cell comprises at least one media access control (MAC) address or group identifier;{'b': 3', '3, 'receiving, by the access network device, a message sent by a terminal, wherein the message comprises a MAC address or a group identifier of the terminal; and'}determining, by the access network device based on whether the MAC address or the group identifier of the terminal exists in the access list of the cell, whether the terminal can access the cell.2. The network access method according to claim 1 , wherein the method further comprises:sending, by the access network device, common configuration information, wherein the common configuration information indicates common configuration parameters of a working group, the common configuration information carries a group radio network temporary identifier (RNTI), there is a correspondence between the group RNTI and a group identifier of the working group, and the working group comprises at least one terminal.3. The network access method according ...

DATA TRANSMISSION METHOD AND APPARATUS

According to embodiments of this application, a terminal device may indicate, to a network device, that at least two uplink grants are required for a to-be-sent data packet; or a terminal device sends, to a network device, indication information used to determine that at least two uplink grants are required for a to-be-sent data packet, so that the network device sends the at least two uplink grants for the to-be-sent data packet. Then, the terminal device assembles the to-be-sent data packet into at least two transport blocks, and sends the at least two transport blocks to the network device by using uplink resources indicated by the at least two uplink grants, to reduce a probability that the terminal device completely transmits the to-be-sent data packet at a time, thereby reducing continuous packet loss. This prevents a receiver manipulator from entering a deadlock state. 1. A data transmission method , comprising:sending, by a terminal device, first information to a network device, wherein the first information is used to indicate that at least two uplink grants are required for a to-be-sent data packet of the terminal device, or the first information is used to determine that at least two uplink grants are required for a to-be-sent data packet of the terminal device;receiving, by the terminal device, the at least two uplink grants from the network device; andassembling, by the terminal device, the to-be-sent data packet into at least two transport blocks, and separately sending the at least two transport blocks to the network device by using uplink resources indicated by the at least two uplink grants.2. The method according to claim 1 , wherein the sending claim 1 , by a terminal device claim 1 , first information to a network device comprises:sending, by the terminal device, at least two buffer status reports (BSRs) to the network device, wherein each BSR is used to indicate a data amount of a to-be-sent data packet corresponding to the BSR.3. The method ...

INFORMATION TRANSMISSION METHOD AND APPARATUS

This application discloses an information transmission method and apparatus, and relates to the field of wireless communications technologies. The method in this application includes: receiving first resource configuration information, where the first resource configuration information is used to indicate a transmission resource of downlink control information, the downlink control information includes information used to indicate a transmission resource of a first message in a random access process and/or information used to indicate a transmission resource of a second message in the random access process, the first message includes a random access response message, and the second message includes a contention resolution message; and then receiving the first message and/or the second message based on the downlink control information. This application is applicable to a random access procedure. 1. An information transmission method , comprising:receiving downlink control information corresponding to a message;when a reception time window of the message starts or ends within a continuous monitoring time period of a control resource set (CORESET) corresponding to the message, determining that the downlink control information is not received on the CORESET; andreceiving the message corresponding to the downlink control information.2. The information transmission method according to claim 1 , wherein the downlink control information is carried on a physical downlink control channel (PDCCH) claim 1 , and the CORESET comprises a time-frequency resource of the PDCCH.3. The information transmission method according to claim 1 ,wherein the downlink control information is received on a CORESET completely located in a reception time window other than the CORESET corresponding to the continuous monitoring time period.4. The information transmission method according to claim 1 , wherein the message comprises a random access response (RAR) message.5. The information transmission ...

Method for Increasing the Activity of Lysosomal Enzymes

Method for enhancing in a mammalian cell the activity of an enzyme associated with Gaucher Disease by administering a competitive inhibitor of glucocerebrosidase in an amount effective to enhance the activity of the enzyme. Preferred compounds for use in the method are imino sugars and related compounds. In particular, C8-12-alkyl derivatives of N-alkyl-deoxymojirimycin, isofagomine compounds, and calystegine compounds are effective to enhance glucocerebrosidase activity. 1. Method of treating Hurler-Scheie disease in a subject in need thereof , comprising administering to the subject an effective amount of a competitive inhibitor of α-L-iduronidase.2. The method of claim 1 , wherein the competitive inhibitor is 1-deoxyiduronojirimycin.3. The method of claim 1 , wherein the competitive inhibitor is 2-carboxy-3 claim 1 ,4 claim 1 ,5-trideoxypiperidine.4. A method for increasing in a mammalian cell the activity of α-L-iduronidase claim 1 , which method comprises contacting the cell with a reversible competitive inhibitor of the α-L-iduronidase in an amount effective to increase α-L-iduronidase activity.5. The method of claim 4 , wherein the competitive inhibitor is 1-deoxyiduronojirimycin.6. The method of claim 4 , wherein the competitive inhibitor is 2-carboxy-3 claim 4 ,4 claim 4 ,5-trideoxypiperidine. This application is a continuation of allowed application Ser. No. 10/989,258, filed Nov. 16, 2004, which is a continuation of application Ser. No. 10/304,395, filed on Nov. 26, 2002, now U.S. Pat. No. 6,916,829, which is a continuation of application Ser. No. 09/948,348, filed on Sep. 7, 2001, now U.S. Pat. No. 6,599,919, which is a continuation of application Ser. No. 09/604,053, filed on Jun. 26, 2000, now U.S. Pat. No. 6,583,158, which is a continuation-in-part of application Ser. No. 09/087,804, filed on Jun. 1, 1998, now U.S. Pat. No. 6,274,597. Each of these prior references are hereby incorporated herein by reference in their entireties.1. Field of the ...

DATA COMPRESSION METHOD AND BASE STATION

Embodiments of this application disclose example data compression methods and example base stations. One example method includes obtaining, by a base station, identification information of at least one of a data compression device or a data decompression device. A dictionary can then be generated based on the identification information. The dictionary can then be sent to the data compression device and the data decompression device to enable the data compression device and the data decompression device to perform data compression and data transmission based on the dictionary. 1. A data compression method , comprising:obtaining, by a base station, identification information of at least one of a data compression device or a data decompression device;generating a dictionary based on the identification information; andsending the dictionary to the data compression device and the data decompression device to enable the data compression device and the data decompression device to perform data compression and data transmission based on the dictionary.2. The method according to claim 1 , wherein after the sending the dictionary to the data compression device and the data decompression device claim 1 , the method further comprises:sending the dictionary to a third-party control device for storage; andwhen the base station is powered off and then powered on again, obtaining the dictionary from the third-party control device.3. The method according to claim 1 , wherein before the obtaining claim 1 , by a base station claim 1 , identification information of at least one of a data compression device or a data decompression device claim 1 , the method further comprises:receiving, by the base station, a service start message sent by the data decompression device or a third-party control device; anddetermining a to-be-used data compression algorithm based on a type of a data packet header indicated by the service start message, wherein the to-be-used data compression algorithm ...

Pharmacological Chaperones for Treating Obesity

The invention relates to methods of enhancing normal melanocortin-4 receptor (MC4R) activity, and to enhancing activity of an MC4R having a mutation which affects protein folding and/or processing of the MC4R. The invention provides a method of treating an individual having a condition in which increased activity of an MC4R at the cell surface would be beneficial, for example in obesity, by administering an effective amount of a pharmacological chaperone for the MC4R. The invention provides MC4R pharmacological chaperones which enhance the activity of MC4R. The invention further provides a method of screening to identify pharmacological chaperones which enhance folding of an MC4R in the endoplasmic reticulum (ER), in order to enhance the activity of the MC4R at the cell surface. 143-. (canceled)45. The method of claim 44 , wherein the pharmacological chaperone is administered in a pharmaceutically-acceptable carrier.46. The method of claim 44 , wherein the pharmacological chaperone is administered orally.47. The method of claim 44 , wherein increasing the mutant MC4R polypeptide activity comprises increasing cAMP activation.48. The method of claim 44 , wherein the mutant MC4R polypeptide is associated with misfolding of the MC4R polypeptide.49. The method of claim 44 , wherein the mutant MC4R polypeptide comprises the mutation P78L claim 44 , R165Q claim 44 , R165W claim 44 , C271Y claim 44 , T11A claim 44 , A175T claim 44 , I316L claim 44 , I316S claim 44 , I317T claim 44 , N97D claim 44 , G98R claim 44 , N62S claim 44 , C271R claim 44 , S58C claim 44 , N97D claim 44 , Y157S claim 44 , I102S claim 44 , L106P claim 44 , L250Q claim 44 , Y287X claim 44 , or S58C.50. The method of claim 49 , wherein the mutant MC4R polypeptide comprises the mutation S58C claim 49 , N62S claim 49 , R165Q claim 49 , R165W claim 49 , or C271Y.52. The method of claim 51 , wherein the pharmacological chaperone is administered in a pharmaceutically-acceptable carrier.53. The method of claim ...

Composition including a fluorinated polymer and a non-fluorinated polymer and methods of making and using the same

A composition is disclosed that includes fluorinated polymer and a non-fluorinated polymer. The fluorinated polymer includes first divalent units independently represented by formula and second divalent unit independently comprising a pendent cationic, anionic, amphoteric, or amine-oxide group or a pendent poly(alkyleneoxy) segment. The non-fluorinated polymer is R 2 O-(EO) p —(R 3 O) q -(EO) p —R 2 or R 2 O—(R 3 O) q -(EO) p —(R 3 O) q —R 2 . A method of making the composition and methods of reducing the surface tension of a liquid and a method of treating a hydrocarbon-bearing formation are also disclosed.

Method of enhancing lysosomal alpha-Galactosidase A

A method of enhancing the activity of lysosomal α-Galactosidase A (α-Gal A) in mammalian cells and for treatment of Fabry disease by administration of 1-deoxy-galactonojirimycin and related compounds. 1. A method of enhancing the activity of lysosomal α-galactosidase A in mammalian cells comprising administering an effective amount of a compound selected from the group consisting of 2 ,5-dideoxy-2 ,5-imino-D-mannitol , 3 ,4-diepz-α-homonojirimycin , 5-O-α-D-galactopyranosyl-α-homonojirimycin , 1-deoxygalactonojirimycin , 4-epi-fagomine , calystegine A3 , calystegine B2 , and calystegine B3 , and N-alkyl derivatives thereof.2. The method of wherein the lysosomal α-galactosidase A is a mutant form which is present in patients with Fabry disease.3. The method of wherein said cells are human cells.4. The method of wherein said cells are the cells of a patient with Fabry disease.5. A method of treating Fabry disease comprising administering an effective amount of a compound selected from the group consisting of 2 claim 3 ,5-dideoxy-2 claim 3 ,5-imino-D-mannitol claim 3 , 3 claim 3 ,4-diepi-α-homonojirimycin claim 3 , 5-O-α-D-galactopyranosyl-α-homonojirimycin claim 3 , 1-deoxygalactonojirimycin claim 3 , 4-epi-fagomine claim 3 , calystegine A3 claim 3 , calystegine B2 claim 3 , and calystegine B3 claim 3 , and N-alkyl derivatives thereof.6. The method of wherein said compound is 1-deoxygalactonojirimycin or 3 claim 5 ,4-diepi-α-homonojirimycin.7. The method of wherein said compound is 1-deoxygalactonojirimycin.8. (canceled) This application claims priority from U.S. patent application Ser. No. 09/927,285, filed on Aug. 10, 2001, which claims priority from U.S. patent application Ser. No. 09/087,804, now U.S. Pat. No. 6,274,597, which is hereby incorporated by reference.This invention relates to a method of enhancing the activity of lysosomal .alpha.-Galactosidase A α-Gal A) in mammalian cells and for treatment of glycosphingolipid storage diseases, in particular Fabry ...

LAYOUT DESIGN METHOD AND SYSTEM

A layout design method is disclosed. The layout design method includes: (a) providing an original layout file; (b) performing a redundant via (RV) filling on the original layout file so as to generate a second layout file; (c) merging the second layout file with the original layout file to generate a third layout file; (d) performing a design rule check (DRC) verification on the third layout file by directly invoking a DRC code in a Process Design Kit (PDK); (e) generating, based on a result of the DRC verification, a fourth layout file including DRC errors; (f) performing a layout operation to remove DRC errors from the second layout file using the fourth layout file, so as to generate a fifth layout file; and (g) merging the fifth layout file with the original layout file to generate a sixth layout file. 1. A computer-implemented layout design method , the method to be performed by a system comprising at least one processor and at least one memory , the method comprising:(a) providing an original layout file;(b) performing a redundant via (RV) filling on the original layout file so as to generate a second layout file;(c) merging the second layout file with the original layout file to generate a third layout file;(d) performing a design rule check (DRC) verification on the third layout file by directly invoking a DRC code in a Process Design Kit (PDK);(e) generating, based on a result of the DRC verification, a fourth layout file including DRC errors;(f) performing a layout operation to remove DRC errors from the second layout file using the fourth layout file, so as to generate a fifth layout file; and(g) merging the fifth layout file with the original layout file to generate a sixth layout file.2. The method according to claim 1 , wherein after merging the fifth layout file with the original layout file to generate the sixth layout file claim 1 , the method further comprising:(h) determining whether an actual number of DRC verifications is the same as a preset ...

Random Access Method and Apparatus

A random access method includes working, by a user equipment (UE), on a first bandwidth part (BWP), where the first BWP is a currently active BWP, when the UE needs to perform a random access procedure, the UE performs the random access procedure on an initial BWP or on the first BWP, and when the UE receives BWP switching indication information from a network device instructing the UE to use a second BWP when performing the random access procedure on the first BWP, continuing, by the UE, to perform the random access procedure on the first BWP, or stopping, by the UE, performing the random access procedure on the first BWP, and performing the random access procedure on the second BWP. 123.-. (canceled)24. A random access method implemented by a user equipment (UE) , comprising:working on a first bandwidth part (BWP), wherein the first BWP is a currently active BWP; and performing the random access procedure on an initial BWP when the first BWP does not meet a first condition for performing the random access procedure; and', 'performing the random access procedure on the first BWP when the first BWP meets the first condition,, 'when the UE performs a random access procedure receiving BWP switching indication information from a network device when the UE performs the random access procedure on the first BWP, wherein the BWP switching indication information instructs the UE to use a second BWP; and', 'either continuing to perform the random access procedure on the first BWP, or stopping performing the random access procedure on the first BWP and initiating the random access procedure on the second BWP., 'wherein the random access method further comprises25. The random access method of claim 24 , further comprising:identifying that the initial BWP meets the first condition; andperforming, in response to the identifying, the random access procedure on the initial BWP.26. The random access method of claim 24 , further comprising:identifying that the second BWP meets the ...

Data Sending Method And Communications Device

Example data sending methods and apparatus are described. One example method includes sending a first message to a network device by a terminal device. The first message is used to indicate information about remaining time of each of one or more data packets. The remaining time of each of the one or more data packets is used to indicate that the terminal device needs to finish sending each of the one or more data packets before the end of the remaining time. The terminal device obtains information about a resource configured by the network device for the terminal device, wherein the resource is used to send each of the one or more data packets before the end of the remaining time. 1. A data sending method , comprising:sending, by a terminal device, a first message to a network device, wherein the first message is used to indicate information about remaining time of each of one or more data packets, and wherein the remaining time of each of the one or more data packets is used to indicate that the terminal device needs to finish sending each of the one or more data packets before an end of the remaining time; andobtaining, by the terminal device, information about a resource configured by the network device for the terminal device, wherein the resource is used to send each of the one or more data packets before the end of the remaining time.2. The method according to claim 1 , wherein the first message is a first scheduling request claim 1 , and wherein the method further comprises:determining, by the terminal device, a configuration of the first scheduling request based on a first correspondence and the remaining time of each of the one or more data packets, wherein the first correspondence is a correspondence between a configuration of a scheduling request and the remaining time of each of the one or more data packets, and wherein the configuration of the first scheduling request comprises a resource position occupied by the first scheduling request; and 'sending, ...

RAIL TRANSIT COMMUNICATION METHOD AND SYSTEM

A method and a system for rail transit communication. The method includes: selecting a second target FSO transceiver from the FSO transceivers that are currently located within a signal coverage of a target FSO base station, in response to detecting that a first target free-space-optics (FSO) transceiver moves out of the signal coverage of the target FSO base station when data communication between the target FSO base station and the target user terminal is performed via the first target FSO transceiver, where the target FSO base station is one of the FSO base stations located on the rail; and maintaining the data communication between the target FSO base station and the target user terminal, by using the second target FSO transceiver. Handover among the base stations is reduced for user equipment, data communication rate is increased, and communication experience of passengers can be improved. 1. A method for rail transit communication , applied to a system for rail transit communication ,wherein the system comprises FSO transceivers and a central controller that are located on a train, and FSO base stations located on a rail, and detecting that a first target FSO transceiver moves out of a signal coverage of a target FSO base station when data communication between the target FSO base station and the target user terminal is performed via the first target FSO transceiver, wherein the target FSO base station is one of the FSO base stations located on the rail;', 'selecting a second target FSO transceiver from the FSO transceivers that are currently located within signal coverage of target FSO base station; and, 'wherein the method comprisesmaintaining the data communication between the target FSO base station and the target user terminal, by using the second target FSO transceiver.2. The method for rail transit communication according to claim 1 , wherein selecting the second target FSO transceiver from the FSO transceivers that are currently located within the ...

Time synchronization method, access network device, communication apparatus, computer storage medium, and communication system

This application provides a time synchronization method, an access network device, a communication apparatus, a computer storage medium, and a communication system. The method includes: A first access network device obtains first indication information, where the first indication information is used to indicate that a first terminal has a requirement for receiving or sending an uplink time synchronization message, and/or the indication information is used to indicate a precision requirement for time synchronization between the first terminal and a wireless network. The first access network device performs time synchronization on the first terminal based on the first indication information. This can avoid a case in which a requirement on a synchronization error of a time sensitive network TSN in an uplink time synchronization scenario cannot be met due to an excessively large air interface synchronization error, so that synchronization between TSN devices is improved, and TSN performance is improved.

Halogen-free, flame retardant TPU composite

Halogen-free TPU compositions comprise in weight percent based on the weight of the composition: A. 1 to 99% thermoplastic polyurethane (TPU), B. 1 to 50% tris(2-butoxyethyl)phosphate (TBEP), C. 1 to 70% metal hydrate, and D. 1 to 70% organic phosphate ester other than tris(2-butoxyethyl)phosphate. These compositions exhibit better smoke suppression as compared with conventional organic phosphate flame retardant TPU compositions such as those based on resorcinol bis(diphenyl phosphate) (RDP) and bisphenol-A bis(diphenyl phosphate) (BPADP) in the absence of TBEP.

Method of contacting hydrocarbon-bearing formations with fluorinated ionic polymers

Glucoimidazole and polyhydroxycyclohexenyl amine derivatives to treat gaucher disease

The present invention provides glucoimidazole (GIZ) and polyhydroxycyclohexenyl amine (PHCA) derivatives, methods of making them, and methods of use where the GIZ and PHCA derivatives have a short, flexible linker emanating from the corresponding position of the ring oxygen in a pyranose; and a lipophilic moiety connected to the linker and pharmaceutically acceptable salts thereof. More particularly, the present invention further provides a method for treating individuals having Gaucher disease by administering the novel GIZ or PHCA derivatives as ~chaperones~ for the mutant glucocerebrosidase associated with the disease.

Data transmission method and apparatus

Embodiments of this application provide a data transmission method and an apparatus. When a time-frequency resource used by a terminal device for data transmission is unavailable, the terminal device postpones, based on indication information of a network device and/or according to a postponement rule, the data transmission to a time-frequency resource closest to the time-frequency resource. Therefore, a data transmission latency is reduced.

Pharmacological chaperones for treating obesity

The invention relates to methods of enhancing normal melanocortin-4 receptor (MC4R) activity, and to enhancing activity of an MC4R having a mutation which affects protein folding and/or processing of the MC4R. The invention provides a method of treating an individual having a condition in which increased activity of an MC4R at the cell surface would be beneficial, for example in obesity, by administering an effective amount of a pharmacological chaperone for the MC4R. The invention provides MC4R pharmacological chaperones which enhance the activity of MC4R. The invention further provides a method of screening to identify pharmacological chaperones which enhance folding of an MC4R in the endoplasmic reticulum (ER), in order to enhance the activity of the MC4R at the cell surface.

Hydroxy piperidine derivatives to treat gaucher disease

The present invention provides novel hydroxy piperidine (HP) derivatives having (i) a positive charge at the position corresponding to the anomeric position of a pyranose ring; (ii) a short, flexible linker emanating from the corresponding position of the ring oxygen in a pyranose; and (iii) a lipophilic moiety connected to the linker and pharmaceutically acceptable salts thereof. The linker can be absent if the lipophilic moiety corresponds to a hydrocarbon chain with a linear length of 6 or more carbons. The present invention further provides a method for treating individuals having Gaucher disease by administering the novel HP derivative as 'chaperones' for the mutant glucocerebrosidase associated with the disease.

Combination therapy for treating protein deficiency disorders

A stable pharmaceutical composition formulated for parenteral administration to a human and comprising a purified recombinant human wild-type α-galactosidase A and 1-deoxygalactonojirimycin in a pharmaceutically acceptable carrier.

Polysiloxane-based protective coating composition for hard surfaces

The present disclosure relates to a protective coating composition for a hard surface, wherein the composition comprises an organic solvent and a polysiloxane having the general formula (I):         (R⁸)_3-p(R⁷O)_pSi-M-Z-B-Si(R³)(R⁴)-[-O-Si(R¹)(R²)-]_n-A-Y-L-Si(OR⁵)_m(R⁶)_3-mwherein:R¹, R², R³, R⁴, R⁵, R⁶, R⁷and R⁸are independently an alkyl group having from 1 to 8 carbon atoms;Y and Z are independently a divalent linking group selected from the group consisting of urea, urethane, oxygen atom, sulfur atom and alkylene having from 1 to 8 carbon atoms;A, B, L and M are independently a divalent linking group selected from the group consisting of alkylene having from 1 to 8 carbon atoms, with the proviso that if the combined linking groups formed by -A-Y-L- and -M-Z-B- are independently an alkylene, then the alkylene is independently different from ethylene;n is an integer from 5 to 1500; andm and p are independently an integer from 1 to 3.In another aspect, the present disclosure is directed to a method of reducing contamination from a hard surface.

Method of enhancing lysosomal α-galactosidase A

A method of enhancing the activity of lysosomal α-Galactosidase A (α-Gal A) in mammalian cells and for treatment of Fabry disease by administration of 1-deoxy-galactonojirimycin and related compounds.

Imaging device having light field image sensor

A method of imaging a target object with an imaging reader. The method includes the following: (1) detecting light from the target object through a lens arrangement with an image sensor to generate light-field data; (2) generating a stream of image data including image data representing an expected in focus image of the target object, and (3) processing the expected in focus image of the target object to decode a barcode on the target object. The image sensor includes an array of photosensitive elements and an array of microlenses that overlays the array of photosensitive elements located at a focus plane of the microlens.

Combination therapy for treating protein deficiency disorders

This application provides methods of improving protein replacement therapy by combining protein replacement therapy with active site-specific chaperones (ASSC) to increase the stability and efficiency of the protein being administered. The application further provides compositions comprising the purified protein and an ASSC, and methods of treatment by administering the compositions.

Method of enhancing lysosomal .alpha.-galactosidase a

A method of enhancing the activity of lysosomal .alpha.-Galactosidase A (.alpha.-Gal A) in mammalian cells and for treatment of Fabry disease by administration of 1-deoxy-galactonojirimycin and related compounds.

Method for enhancing mutant enzyme activities in lysosomal storage disorders

Method for enhancing in a mammalian cell the activity of an enzyme associated with a lysosomal storage disorder by administering a competitive inhibitor of the enzyme in an amount effective to enhance the activity of the enzyme. Preferred compounds for use in the method are imino sugars and related compounds.

V2x communication method and apparatus

Combination therapy for treating protein deficiencies

This application provides methods of improving gene therapy by combining gene therapy with active site-specific chaperones (ASSCs). The ASSC increases the stability and efficiency of the protein encoded by the recombinant gene that is administered.

hydroxypiperidine-derived compound, methods for the synthesis of a hydroxypiperidine-derived compound to inhibit glucocerebrosidase, to increase glucocerebrosidase activity in a mammalian cell and to stabilize glucocerebrosity, pharmaceutical composition, methods to inhibit beta-glucosity, and to treat gaucher disease and hydroxypiperidine derivative with short flexible binder

"composto derivado de hidroxipiperidina, métodos para a síntese de um composto derivado de hidroxipiperidina para inibir glicocerebrosidase, para aumentar a atividade de glicocerebrosidase numa célula de mamífero e para estabilizar glicocerebrosidade, composição farmacêutica, métodos para inibir <225>glicosidase, e para tratar doença de gaucher e derivado de hidroxipiperidina com ligante flexível curto". a presente invenção refere-se a derivados de hidroxipiperidina (hp)novos com (i) uma carga positiva na posição correspondente à posição anomérica de um anel de piranose; (ii) um ligante flexível curto procedente da posição correspondente do oxigênio no anel numa piranose; e (iii) uma porção lipofílica conectada ao ligante e seus sais farmaceuticamente aceitáveis. o ligante pode estar ausente se a porção lipofílica corresponder a uma cadeia hidrocarbônica com uma extensão linear de 6 ou mais carbonos. a presente invenção provê ainda um método para tratar indivíduos com doença de gaucher administrando-se o derivado de hp na forma de 'chaperonas' (proteínas ligantes) para a glicocerebrosidade mutante associada com a doença. "hydroxypiperidine-derived compound, methods for the synthesis of a hydroxypiperidine-derived compound to inhibit glucocerebrosidase, to increase glycocerebrosidase activity in a mammalian cell and to stabilize glucocerebrosity, pharmaceutical composition, methods to inhibit <glycosidase, and to treat disease. of gaucher and hydroxypiperidine derivative with short flexible binder ". The present invention relates to novel hydroxypiperidine (hp) derivatives having (i) a positive charge at the position corresponding to the anomeric position of a pyranose ring; (ii) a short flexible binder from the corresponding position of oxygen in the ring in a pyranose; and (iii) a lipophilic moiety attached to the binder and pharmaceutically acceptable salts thereof. The binder may be absent if the lipophilic moiety corresponds to a ...

Data transmission method and apparatus

Method and apparatus provide for receipt by a communication apparatus of first indication information from a second communication apparatus indicating whether a first service of a terminal device is a service of a first type. The communication apparatus obtains characteristic information of the first service based on the first indication information, determines a mapping relationship between a packet filter set of the first service and a quality of service QoS flow based on the characteristic information, and sends the mapping relationship to a third communication apparatus.

Communication method, apparatus and system

The present invention discloses a communication method, an apparatus, and a system that are applicable to a multi-connection scenario. Based on a solution provided in embodiments of the present invention, a first access network device allocates, to a second access network device based on an obtained quantity, supported by a terminal, of data radio bearers DRBs to which a data frame compression function is applied, a quantity of DRBs the second access network device can configure for the terminal and to which the function is appliedcan configure, and notifies the second access network device of an allocation result. According to the method, a total quantity of DRBs that different access network devices configure for the terminal and to which the data frame compression function is applied does not exceed a capability restriction of the terminal. The foregoing solution is also applicable to a packet data convergence protocol replication function and an Ethernet header compression operation function. For allocation of a quantity of contexts maintained for the function, reference may also be made to this solution.

Combination therapy for treating protein deficiency disorders

Combination therapy for treating protein deficiency disorders

This application provides methods of improving protein replacement therapy by combining protein replacement therapy with active site-specific chaperones (ASSC) to increase the stability and efficiency of the protein being administered. The application further provides compositions comprising the purified protein and an ASSC, and methods of treatment by administering the compositions.

Procedure of phone guard

Halogen-free, flame retardant thermoplastic compositions for wire and cable applications

Disclosed is a halogen-free, flame retardant thermoplastic resin composition based on polypropylene and one or more thermoplastic elastomers with an organic nitrogen- and/or phosphorus-based intumescent flame retardant comprising a piperazine component. The composition is processed easily to make a wire and cable sheath exhibiting a balance of high flame retardancy, good flexibility, high wet electrical resistance and excellent heat deformation properties, and which passes the VW-I flame retardancy test, the UL1581 heat deformation test at 150 °C and the wet electrical resistance test, and also exhibits good tensile and flexibility properties. Also disclosed is a wire and cable sheath made from the composition.

Pyridostigmine for the treatment of obstructive sleep apnea

The present invention relates to methods for treating obstructive sleep apnea (OSA), alleviating a negative OSA symptom, reducing snoring, or improving quality of life in a subject, comprising administering to the subject an effective amount of a pharmaceutical composition comprising pyridostigmine before sleep. Also provided are related medicaments as well as methods for preparing the medicaments.

Hydroxy piperidine derivatives to treat Gaucher disease

Communication method and communication apparatus for sidelinks

This application provides a sidelink communication method. The method includes: A first terminal device determines one or more pieces of first configuration information, where the one or more pieces of first configuration information correspond to one or more sidelinks, each piece of the first configuration information is used to configure a discontinuous reception DRX related parameter of a corresponding sidelink, and the first terminal device is a sending device or a receiving device on the one or more sidelinks. The first terminal device maintains, based on each piece of the first configuration information, a status of the discontinuous reception DRX corresponding to each piece of the first configuration information. In this way, power consumption of the terminal device is reduced, and communication reliability is improved.

Formulation comprising mutant (s) of lysosomal alpha-galactosidase A, for the treatment of Fabry's disease

Pharmacological chaperones for treating obesity

The invention relates to methods of enhancing normal melanocortin-4 receptor (MC4R) activity, and to enhancing activity of an MC4R having a mutation which affects protein folding and/or processing of the MC4R. The invention provides a method of treating an individual having a condition in which increased activity of an MC4R at the cell surface would be beneficial, for example in obesity, by administering an effective amount of a pharmacological chaperone for the MC4R. The invention provides MC4R pharmacological chaperones which enhance the activity of MC4R. The invention further provides a method of screening to identify pharmacological chaperones which enhance folding of an MC4R in the endoplasmic reticulum (ER), in order to enhance the activity of the MC4R at the cell surface.

Fire-fighting agents containing adsorbable fluorocarbon surfactants

Fire-fighting concentrate compositions contain fluorinated amine oxide surfactants as well as fluorine free surfactants. Fire-fighting premixes are also provided, as well as a method of fighting fires using the compositions and premixes. These compositions form foams that are effective fire-fighting agents, and in addition the fluorinated amine oxide surfactants adsorb well to dirt, sludge, and other substrates. This adsorption property allows the surfactant to be readily removed from the environment.

Combination therapy for treating protein deficiency disorders

This application provides methods of improving protein replacement therapy by combining protein replacement therapy with active site-specific chaperones (ASSC) to increase the stability and efficiency of the protein being administered. The application further provides compositions comprising the purified protein and an ASSC, and methods of treatment by administering the compositions.

Pharmacological chaperones for treating obesity

The invention relates to use of a pharmacological chaperone, which is a melanocortin 4 receptor (MC4R) polypeptide antagonist of the formula (see above formula)

Method and apparatus for facilitating manufacturing of semiconductor device

A method for facilitating semiconductor device manufacturing may include the following steps: receiving a custom design data set, which complies with a first element-identification scheme; generating a compatible design data set using the custom design data set, wherein data elements in the compatible design data set correspond to data elements in the custom design data set, and wherein the compatible design data set is compatible with a dummy-pattern-data generation module; generating a first dummy-pattern data set using the dummy-pattern-data generation module and the compatible design data set; and generating a second dummy-pattern data set using the first dummy-pattern data set, wherein data elements in the second dummy-pattern data set correspond to data elements in the first dummy-pattern data set, and wherein the second dummy-pattern data set complies with the first element-identification scheme.

Composition including a fluorinated polymer and a non-fluorinated polymer and methods of making and using the same

A composition is disclosed that includes fluorinated polymer and a non-fluorinated polymer. The fluorinated polymer includes first divalent units independently represented by formula and second divalent unit independently comprising a pendent cationic, anionic, amphoteric, or amine-oxide group or a pendent poly(alkyleneoxy) segment. The non-fluorinated polymer is R 2 O-(EO) p -(R 3 O) q -(EO) p -R 2 or R 2 O-(R 3 O) q -(EO) p -(R 3 O) q -R 2 . A method of making the composition and methods of reducing the surface tension of a liquid and a method of treating a hydrocarbon-bearing formation are also disclosed.

Pharmacological chaperones for treating obesity

The invention relates to use of a pharmacological chaperone, which is a melanocortin 4 receptor (MC4R) polypeptide antagonist of the formula (see above formula)

Communication method and apparatus

A communication method and apparatus is provided, to properly schedule retransmission of an uplink resource in a scenario in which uplink resources overlap in time domain. The method includes: determining, by a terminal, that a priority of a first uplink resource is higher than a priority of a second uplink resource in the first uplink resource and the second uplink resource that have an overlapping part in time domain; and when determining to send a signal by using the first uplink resource on the overlapping part, indicating, by the terminal to a network device, whether a MAC PDU is formed for the second uplink resource or whether data is stored in a corresponding buffer for the second uplink resource.

Communication method and communication apparatus

Communication method and related device

Method and apparatus for compressing ethernet header, and method and apparatus for decompressing ethernet header

Embodiments of this application provide an Ethernet header compression method and apparatus and an Ethernet header decompression method and apparatus. After receiving an Ethernet frame including a first to-be-compressed field, a compression end may compress an Ethernet header of the Ethernet frame based on a first correspondence including first compression information and a value of the first to-be-compressed field and the first compression information. Correspondingly, a decompression end may decompress an Ethernet header of a compressed Ethernet frame based on the first correspondence when receiving the compressed Ethernet frame. In the embodiments of this application, because the Ethernet header of the Ethernet frame is compressed, communication resources can be saved.

Pharmacological chaperones for treating obesity

Method for enhancing mutant enzyme activities in lysosomal storage disorders

Method fore enhancing in a mammalian cell the activity of an enzyme associated with a lysosomal storage disorder by administering a competitive inhibitor of the enzyme in an amount effective to enhance the activity of the enzyme. Preferred compounds for use in the method are imino sugars and related compounds.

Radio link control status report method and corresponding apparatus

This application provides a method and a corresponding apparatus. One example method includes: A transmitting side receives an RLC status report from a receiving side, where the RLC status report includes at least one piece of status information, each of the at least one piece of status information indicates one or more receiving statuses of one or more consecutive RLC service data units (SDUs) that are not successfully received, and the at least one piece of status information is sequentially sorted in ascending order of RLC SDU sequence numbers (SNs) in the RLC status report; and if the last piece of status information in the RLC status report indicates that a part of data of a first RLC SDU is lost, the transmitting side determines, based on the RLC status report, whether a receiving status of the first RLC SDU is completely reflected in the RLC status report.

Procedure of acting personally hot function setting

Communication method and apparatus, and computer storage medium

Provided in an embodiment of the present application are a communication method and apparatus, and a computer storage medium, so as to reduce the communication delay between a terminal and a base station, and improve adaptability for delay-sensitive scenes. The method provided in the present application comprises: a terminal receiving at least one uplink configuration and at least one random access configuration from a network device, wherein the uplink configuration is used to indicate parameters for sending uplink data, the random access configuration is used to indicate parameters for sending a preamble, the at least one uplink configuration comprises a first uplink configuration, the at least one random access configuration comprises a first random access configuration, and the first uplink configuration and the first random access configuration have a correspondence; according to the correspondence, the terminal sending uplink data to the network device using the first uplink configuration and sending a preamble to the network device using the first random access configuration. The present application relates to the technical field of communications.

Stable formulations of purified proteins

This application provides methods of improving protein replacement therapy by combining protein replacement therapy with active site-specific chaperones (ASSC) to increase the stability and efficiency of the protein being administered. The application further provides stable compositions comprising the purified protein and an ASSC, and methods of treatment by administering the compositions.

Combination therapy for treating protein deficiencies

This application provides methods of improving gene therapy by combining gene therapy with active site-specific chaperones (ASSCs). The ASSC increases the stability and efficiency of the protein encoded by the recombinant gene that is administered.

Method for automatically switching telephone system to an on-hook state

A method of automatically switching in an on-hook state suitable for a telephone system is provided. The method automatically switches a spring circuit from an off-hook state to the on-hook state when the telephone system operates in an abnormal use state for a unreasonably long period of time. Therefore, the telephone system can be switched back to the on-hook state when the mouthpiece is unintentionally off the hook so the missing of the phone call can be effectively avoided.

Communication method, apparatus, and system

The present invention discloses a communication method, an apparatus, and a system that are applicable to a multi-connection scenario. Based on a solution provided in embodiments of the present invention, a first access network device allocates, to a second access network device based on an obtained quantity, supported by a terminal, of data radio bearers DRBs to which a data frame compression function is applied, a quantity of DRBs the second access network device can configure for the terminal and to which the function is applied can configure, and notifies the second access network device of an allocation result. According to the method, a total quantity of DRBs that different access network devices configure for the terminal and to which the data frame compression function is applied does not exceed a capability restriction of the terminal. The foregoing solution is also applicable to a packet data convergence protocol replication function and an Ethernet header compression operation function. For allocation of a quantity of contexts maintained for the function, reference may also be made to this solution.

PRODUCTS OF 1-DEOXY-LACTONOGIRIMYKIN AND THEIR USE IN THE TREATMENT OF ATHLETIC LYSOSOMIC DISEASES THROUGH ENHANCEMENT OF LYSOSIM A

A method of enhancing the activity of lysosomal ±-Galactosidase A (±-Gal A) in mammalian cells and for treatment of Fabry disease by administration of 1-deoxy-galactonojirimycin and related compounds.

Communication Method and Apparatus

Embodiments of this application provide a communication method and apparatus. The method includes: A first terminal performs integrity protection verification on a received RRC message; and when the integrity protection verification fails, an RRC layer of the first terminal sends a first indication and an identifier of a second terminal to an application layer of the first terminal, where the first indication and the identifier of the second terminal are used by the application layer to disconnect a unicast connection between the first terminal and the second terminal. Based on this solution, when the integrity protection verification performed by the first terminal on the received message fails, the RRC layer of the first terminal may report the first indication and the identifier of the second terminal to the application layer, to trigger the application layer to disconnect the unicast connection between the first terminal and the second terminal.

Communication method and apparatus

汽车smc产品冲切防孔位开裂的结构

本实用新型涉及一种汽车SMC产品冲切防孔位开裂的结构，它包括上浮动模、浮动模镶块、下模仁、冲头固定座、冲头、凹模套，上浮动模位于下模仁上面，上浮动模上安装有浮动模镶块，冲头固定座安装在上浮动模上面，冲头上端安装在冲头固定座内，冲头下端贯穿浮动模镶块之后伸入下模仁上面的凹模套内。优点是设计简单，使用方便，本结构仅仅把要冲切的区域设计成镶块结构，便于型面的调节，其他非冲切区域全部避空设计，减少了浮动上模和产品的接触面积，从而有效的减小了发生开裂的概率，产品表面的划痕现象明显改善。

Data compression method and base station

Embodiments of this application disclose example data compression methods and example base stations. One example method includes obtaining, by a base station, identification information of at least one of a data compression device or a data decompression device. A dictionary can then be generated based on the identification information. The dictionary can then be sent to the data compression device and the data decompression device to enable the data compression device and the data decompression device to perform data compression and data transmission based on the dictionary.

Communication method, apparatus, and system

Disclosed are a communication method, apparatus and system, which can be applied to a multi-connectivity scenario. On the basis of the solution provided in the embodiments of the present invention, a first access network device allocates, according to the number of acquired data radio bearers (DRBs) that are supported by a terminal and apply a data frame compression function, to a second access network device, the number of DRBs that can be configured by the second access network device for the terminal and apply the function, and notifies the second access network device of an allocation result. By using the method, the total number of DRBs that are configured by different access network devices for a terminal device and apply the data frame compression function cannot exceed the capability limit of the terminal. The solution is also applicable to a packet data convergence protocol replication function and an Ethernet header compression operation function. The allocation of the number of contexts maintained for the function can also refer to the solution.

Communication method and communications apparatus

Disclosed are a communication method and device, with a view to enabling a base station to allocate wireless resources to data packets of a TSN network in a scenario where the TSN network transmits data packets through 5G network. The method comprises: an access network device acquires a first service mode, and allocates wireless resources for a first service according to the first service mode. The first service mode includes time information of the first service under a first clock, the first clock is a clock used by a first network, the access network device belongs to the first network, and the time information includes moment and/or cycle when the data packets of the first service reach the first network.

Beam failure recovery method and apparatus, and readable storage medium

A beam failure recovery BFR method and an apparatus are provided. The method includes: A terminal receives indication information of a first threshold and a second threshold, where the second threshold is used to determine that a beam failure occurs on an access network device. The terminal collects statistics on quantities of beam failure instance times of one or more access network devices that communicate with the terminal based on beams in a cell; and performs beam recovery on an access network device whose quantity of beam failure instance times is greater than or equal to the first threshold and less than the second threshold. The method and the apparatus in this application can further reduce a possibility of the beam failure, improve network reliability, and avoid beam failures on a plurality of devices in the cell at the same time.

Beam failure recovery method, apparatus, and readable storage medium

A beam failure recovery BFR method and an apparatus are provided. The method includes: A terminal receives indication information of a first threshold and a second threshold, where the second threshold is used to determine that a beam failure occurs on an access network device. The terminal collects statistics on quantities of beam failure instance times of one or more access network devices that communicate with the terminal based on beams in a cell; and performs beam recovery on an access network device whose quantity of beam failure instance times is greater than or equal to the first threshold and less than the second threshold. The method and the apparatus in this application can further reduce a possibility of the beam failure, improve network reliability, and avoid beam failures on a plurality of devices in the cell at the same time.

用於高速負載暫態響應電力供應系統的裝置與方法以及至少一種機器可讀取式儲存媒體

本揭示內容係關於一種使用動態參考電壓產生之高速負載暫態響應電力供應系統。用於高速負載暫態響應電力供應系統的裝置可包括例如至少電力供應電路、電壓參考電路及動態參考產生電路。電力供應電路可經組態以基於電力供應輸入電壓而產生輸出電壓(例如，用於驅動負載)。電壓參考電路可經組態以產生參考電壓，以用來控制輸出電壓之產生。動態參考產生電路可經組態以基於參考電壓及輸出電壓，產生動態參考電壓作為用於電力供應電路的輸入電壓。

Data transmission method and apparatus

This application provides a data transmission method. The method includes: A terminal device receives indication information from a network device, where the indication information includes a bit sequence, a value of an ith bit in the bit sequence indicate a usage status of an ith logical channel in M logical channels associated with a radio bearer, and a duplication transmission function is configured for the radio bearer; the terminal device transmits data based on the indication information through at least one logical channel associated with the radio bearer; and because the M logical channels are sorted based on IDs of cell groups associated with the M logical channels and IDs of the M logical channels, the ith bit in the bit sequence included in the indication information indicates the usage status of the ith logical channel in the M logical channels.