Benzylbenzene derivatives and methods of use

Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.

BENZYLIC GLYCOSIDE DERIVATIVES AND METHODS OF USE

Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.

Endo-xylanase with high thermal stability and application thereof

The invention discloses endo-xylanase with high thermal stability. By transforming xylanase DtX which is originated from thermophilic microorganism to remove signal peptide, the xylanase gene is efficiently expressed in a heterogenous host cell such as escherichia coli. According to the endo-xylanase, xylanase is further transformed to cut off a carbohydrate combined structural domain and introduce a disulfide bond at the tail end C, so that the constructed xylanase protein mutant is less in molecular weight, the thermal stability is improved and the specific activity is further greatly improved. By the above manner, the xylanase and the mutant of the xylanase have relatively large potential and are applied to industrial production.

Nimesulide dry suspension and preparation method thereof

The invention discloses a double-bag packaged nimesulide dry suspension. The double-bag packaged nimesulide dry suspension is prepared by the following steps: uniformly mixing 10 to 200 weight parts of nimesulide, 300 to 1,500 weight parts of filling agent, 100 to 500 weight parts of viscosity agent, 10 to 200 weight parts of flow aid, 5 to 10 weight parts of sweetener, and 1 to 3 weight parts of essence; crashing the mixture; screening the mixture with a screen of 30 to 40 meshes; mixing the mixture uniformly; placing the mixture in a novel powder feed device; and performing heat-sealing on the novel powder feed device with a powder-packing double-sealing device. Compared with the prior production technology, the nimesulide dry suspension prepared by the invention is convenient to administrate according to dose, has accuracy dose, and overcomes the defects that the quality is easy to change after single-bag package is unsealed and that the secondary pollution is easily caused by repeatedly ...

Multi -functional fire -tongs is used in laboratory

The utility model discloses a multi -functional fire -tongs is used in laboratory, this multi -functional fire -tongs is used in laboratory, by two tong arm (1) and one grafter (2) constitution of intercrossing, two tong arms pass through swivel pin (3) to be connected, and two tong arms upper end has handle (4), and two tong arm lower extremes have a facade S type pincers mouth (5), and pincers mouth medial surface is equipped with the stripe, grafter (2) are located the symmetrical line of two tong arms, and the grafter initiating terminal passes through threaded connection or welded fastening on the swivel pin. The utility model discloses a not only improve the security and the reliability of the cubic material process of taking greatly, what increased powdered and graininess material in addition takes and stirs the mixed function, has realized multi -functional integration, easy operation, and convenient to use is favorable to that the experiment is safe to be gone on smoothly, and ...

An electric-biology-coupled water purification system with gas and water flowing at different directions and a water purification method

An electric-biology-coupled water purification system with gas and water flowing at different directions and a water purification method are disclosed. A biological filtering material layer of the water purification system is disposed below a three-dimensional particle electrode layer. The three-dimensional particle electrode layer is connected to the biological filtering material layer through a stainless steel perforated plate. The bottom of the biological filtering material layer is connected to an aeration water discharging chamber through a manner of a plastic perforated plate. The aeration water discharging chamber is connected to an aeration device. Gas and water in the whole system flow at different directions, wherein the gas flows from bottom to top and the water flows from top to bottom. The water purification method includes steps of: (1) feeding raw water into a water distributing chamber; (2) performing electrocatalytic oxidation; (3) physically filtering and intercepting; ...

Module connecting 2B+D scheduling desks by E1 line and method

The invention discloses a module connecting 2B+D scheduling desks by an E1 line and a method, belonging to the technical field of data transmission. The module comprises 2B+D interfaces, a 2B+D and E1 conversion unit and an E1 interface which are connected in sequence; the method for connecting the scheduling desks comprises the following steps of: randomly selecting three non-zero time slots of the E1 line and leading signals of two B channels and signals of one D channel to be respectively transmitted by the three selected time slots along the E1 line; the method for connecting 2 to 10 scheduling desks is as follows: the time slots 1, 2 and 3 of the E1 line are respectively used for transmitting 2B+D signals of the first scheduling desk; the time slots 4, 5 and 6 are respectively used for transmitting 2B+D signals of the second scheduling desk; and so forth, till the 31 time slots of the E1 line are distributed completely. The invention replaces the twisted pair cable with the E1 line ...

METHOD OF PREPARING OIL ABSORBING FIBERS

A method of preparing oil-absorbing fibers by: a) fully dissolving a dispersant and a deionized water in a reaction vessel, adding a methacrylate monomer and an initiator to a reactor and stirring to form a homogenous solution, transferring the homogenous solution into the reaction vessel, charging nitrogen gas, stirring, raising temperature to 70-80° C., allowing to react for 2-6 hours, raising temperature to 90-100° C., allowing to react for 2-4 hours, collecting a resultant product, washing, drying, and obtaining a white resin; b) drying the white resin, mixing with a swelling agent, and sealing the mixture at room temperature for 48-96 hours to yield a homogenous gel; c) grinding the gel completely, spinning by a plunger spinner, and coagulating with a coagulation bath to yield an as-spun oil-absorbing fiber; and d) drawing the as-spun oil-absorbing fiber with a draw ratio of 2-6 to yield oil-absorbing fibers.

Detection of molecular interactions using a field effect transistor

HÄMOVERTRÄGLICHES BONDING MATERIAL.

Method and apparatus for optimizing product distribution strategies and product mixes to increase profitability in complex computer aided pricing of products and services

NARROW BAND FIBER RAMAN OPTICAL AMPLIFIER

The invention refers to an optical Raman fiber amplifier (20), with an amplification fiber, wherein at least one section thereof has a ratio of Raman gain coefficient g R to Brillouin g B gain coefficient of g R/g B larger than 0.001 at the fiber operating temperature and a vacuum wavelength of 1064 nm. The invention further refers to a corresponding light source, the use of a fiber and a method of amplifying light.

HISTONE ACETYLTRANSFERASE MODULATORS AND USESE THEREOF

The invention provides compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a compound that modulates HAT to a subject.

Advanced control method and system for complex lagged process

It is an advanced control method and its realization method for complicated lag process, which at least comprises: to predict the future output value of the complicated lag process; to predict the current output value of the process; to correct and feedback the process on-line; to optimize the process; to judge the optimized ration calculated according to the limits and get the control increment of those satisfy the limit conditions and to exert them in the controlled process. This invention selects relevant process variable as state variable based on the detail condition and measuring point in the process and uses the measured the state variable to calculate optimized control ratio. And it realizes the feedback design of the measured state and enhances the application area of the controller process change and operation control change and increase the robust stability and anti-interference abilities of the control system.

Desulfurated circulating water purification treatment equipment and method

The invention provides desulfurated circulating water purification treatment equipment which comprises a hot water pool, a dosing device, a precipitation device and a filter, wherein a water outlet of the hot water pool is connected with a water inlet of the dosing device, a water outlet of the dosing device is connected with a water inlet of the precipitation device, a supernatant outlet on the upper part of the precipitation device is connected to the hot water pool, a concentrated solution outlet on the bottom of the precipitation device is connected to a water inlet of the filter, and a water outlet of the filter is connected to the hot water pool. The desulfurated circulating water purification treatment equipment and technology of the invention can be realized in a way that: adding coagulant and flocculating agent to the desulfurated circulating water so that solid particles in the desulfurated circulating water flocculate, and precipitating and filtering to remove the solid particles ...

Flour model material

The present invention relates to a material for producing handiwork of dough figurine, particularly to a dough modelling material, which solves the problems of difficult manufacture, easy cracking, putrescibility and short preservation time of the dough figurines due to the improper proportion of raw materials in dough modelling material in prior art. The dough modelling material is prepared by 550 to 650 weight parts of wheat flour (weak flour), 130 to 180 weight parts of glutinous rice flour, 80 to 120 weight parts of white sugar, 70 to 80 weight parts of preservative substance and 400 to 500 weight parts of water. The handicrafts with various figurines produced by the dough modelling material of the invention scarcely crack, the surface of the production is stable, crackless, mildewproof and moistureproof. The structural strength is strong, and normal collision can not cause any damage. The product having the same character of plasticene employs pure natural edible materials, inherits ...

Technological method for gate oxide layer

The invention discloses a technological method for a gate oxide layer. The method comprises the steps that (1) oxygen is led into a furnace tube, and thermal growth of the gate oxide layer is carried out; (2) under the oxygen-bearing atmosphere, first-time annealing is carried out at the temperature being 1050 DEG C; (3) under the nitrogen-bearing atmosphere, second-time annealing is carried out at the temperature being 1050 DEG C. According to the technological method, the technology that step-by-step annealing is carried out under the oxygen-bearing atmosphere and the nitrogen-bearing atmosphere successively is adopted for improving the performance of the gate oxide layer, and leakage current of the device is reduced.

Blast furnace metallurgical slag based particle electrode and preparation method thereof

The invention discloses a blast furnace metallurgical slag based particle electrode and a preparation method thereof, and belongs to the technical field of wastewater treatment. The blast furnace metallurgical slag based particle electrode is prepared as follows: blast furnace metallurgical slag, shale, a pore forming agent, and an activating agent, which are processed by ball milling and drying, are used as raw materials, mixed in certain weight proportion, and extruded into raw material balls, the raw material balls are dried, and processed by heating, activation and roasting at a particular temperature, after a period of time, the raw material balls are taken out, and cooled to room temperature to obtain the finished product. The prepared blast furnace metallurgical slag based particle electrode is porous, large in pore size, large in specific surface area, and good in adsorption, and is a new and efficient particle electrode. According to the blast furnace metallurgical slag based particle ...

Production method for oil suction fibre

The invention relates to a production method of an oil absorbent fiber. The production technique of the invention is as follows: 1. dispersant and deionized water are added into a reaction vessel, and the weight of the dispersant is 0.1 to 1 percent of the weight of methacrylate monomer and the volume of the deionized water is 3:1 of the volume of the methacrylate monomer; after full dissolving, the methacrylate monomer and the initiator are put into a container, the weight of the initiator is 0.1 to 1 percent of the weight of methacrylate monomer, and stirring evenly is carried out so as to obtain the homogeneous solution; the solution is put into the reaction vessel, and nitrogen is led to the vessel, the mixture is stirred to ensure the temperature to rise to 70 to 80 DEG C, after reacting for 2 to 6h, the reaction temperature is increased to 90 to 100 DEG C so as to ensure the mixture continue to react for 2 to 4h, then the reaction is stopped, the product is taken out, and the product ...

Application of barbaloin in prevention and treatment of allergic rhinitis and asthma syndrome

The invention relates to the technical field of compound medicines, in particular to application of barbaloin in preventing and treating allergic rhinitis and asthma syndromes, and the allergic rhinitis and asthma syndromes comprise clinical or subclinical upper respiratory tract allergy and lower respiratory tract allergic symptoms, type I allergy of allergic rhinitis and asthma, type II allergy of aloin, type II allergy of aloin, type III allergy of aloin, type III allergy of aloin, type III allergy of aloin, type III allergy of aloin and type III allergy of aloin. The use amount of the barbaloin is 10000-30000 U/ml/d. The pharmaceutical composition disclosed by the invention can bring positive anti-inflammatory activity, tumor development inhibition, osteoporosis resistance, pathogenic organism resistance, metabolic regulation and organ protection effects to a patient in a treatment process.

Benzylphenyl cyclohexane derivatives and methods of use

METHOD AND APPARATUS FOR AUTOMATIC CROSS-SYSTEM PROGRAM DEBUGGING

The present invention discloses a method and apparatus for automatic cross-system program debugging. One embodiment of the present invention provides a method for cross-system program debugging. The method comprises: determining a first breakpoint in a first debugging session of a first system; determining a second breakpoint in a second debugging session of a second system, the second system being different from the first system; and responsive to a user performing a debugging action of associating the first breakpoint with the second breakpoint in the first debugging session and the second debugging session, recording an association between the first breakpoint and the second breakpoint for automating the program debugging across the first system and the second system. There is further described a corresponding apparatus.

OPTICAL NARROW BAND FIBER RAM ON AMPLIFIER

Targeting construct comprising anti-polymer antibody and liposomes or microvesicles binding to the same

Assembly of gas-filled microvesicle with active component for contrast imaging

Gas mixtures useful as ultrasound contrast media

Antibodies against OX40 and uses thereof

Provided herein are antibodies, or antigen binding portions thereof, that bind to OX40. Also provided are uses of these proteins in therapeutic applications, such as in the treatment of cancer. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain variable region of the antibodies, and vectors comprising the polynucleotides encoding the heavy and/or light chain variable region of the antibodies.

COMPOUND AND USE THEREOF IN SYNTHESIS OF BRIVARACETAM INTERMEDIATE AND CRUDE DRUG

The present application provides a compound in formula III, and further provides a use of the compound in the synthesis of a Brivaracetam intermediate and a crude drug, and a synthesis method. A raw material involved in the method of the present application is low in costs and easily available; (R)-4-propyl-dihydrofuran-2-ketone having high optical purity can be prepared; complicated separation and purification steps are avoided; costs are reduced, and the method is more applicable to industrial production.

SHAPE SHIFTING HAMPER AND BAG

A container takes on the form of a laundry hamper or basket while static or stationary. Upon bringing front and back panels of the container into closer proximity for transport, such as by drawing together their respective handles, or drawing one of the handles towards the other, the container changes configuration, or shape, to that of a tote bag. Upon releasing at least one of the front and back panels of the container from being drawn towards the other, such as by releasing at least one of their respective handles, the container automatically reverts back to the form of a laundry hamper or basket. The use of substantially rigid front and back panels, coupled with side panels that have resilient upper regions, permit the side panels to take on a spout-like configuration when the container is in its tote bag configuration, and to return to a planar configuration when the container is in its laundry hamper or basket configuration.

HISTONE ACETYLTRANSFERASE MODULATORS AND USES THEREOF

The invention provides compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a compound that modulates HAT to a subject. In one aspect the compound might be a compound of formula (I): (see formula I) ...

BENZYLIC GLYCOSIDE DERIVATIVES AND METHODS OF USE

Provided are compounds having an inhibitory effect on sodium-dependent gl ucose cotransporter SGLT. The invention also provides pharmaceutical composi tions, methods of preparing the compounds, synthetic intermediates, and meth ods of using the compounds, independently or in combination with other thera peutic agents, for treating diseases and conditions which are affected by SG LT inhibition.

Energy -conserving vibration fluidized bed dryer

The utility model discloses an energy -conserving vibration fluidized bed dryer, the processing of mainly used chicken essence seasoning, including box, upper cover, the box middle part is equipped with the fluidization bed board, the fluidization bed board with be equipped with shock dynamo between the bottom half, one side of box is equipped with the air intake, air intake department is equipped with the air heater, the air intake for the opposite side of air heater is equipped with the steam heat air curtain, the steam heat air curtain with be equipped with the air register between the air heater, the box for the opposite side of air intake is equipped with the discharge gate, the upper cover top is equipped with the air outlet, be equipped with bag dust filter in the air outlet. Have that drying rate is fast, energy saving, the occupation of land is little, the big energy consumption of productivity is little, the recruitment is few a great deal of advantage.

Method for enriching and purifying icariin in epimedium herb

The invention belongs to the field of natural organic chemistry and relates to a method for enriching and purifying icariin in epimedium herb by a batch distillation-macro absorption resin coupling method. The method is characterized in that: icariin is separated and purified by the batch distillation-macro absorption resin coupling method, the adsorption selectivity to icariin is high, adsorption and resolution are quick and adsorption volume is large; and extraction is convenient and quick, raw materials are readily available, production cost is low, separation effect is remarkable, extraction purity is high, an icariin semi-finished product with the icariin content of over 35 percent and an icariin finished product with the icariin content of over 95 percent can be obtained, and the defects of low extraction rate and low extraction purity by the conventional method are overcome. Macro absorption resin with stable physicochemical property, a large surface area, high exchange speed, high ...

Method for enriching and purifying folic acid in houseleek by macroporous absorbent resin

The invention relates to a method for enriching and purifying folic acid in houseleek by macroporous absorbent resin, which belongs to the field of natural organic chemistry. The invention is characterized in that the macroporous absorbent technology is used for separating and purifying the folic acid, the adsorption selectivity on the folic acid is good, both the adsorption and the desorption are fast, the adsorption capacity is large, the extraction is convenient and fast, the raw material sources are rich, the production cost is low, the separation effect is obvious, the extraction purity is high, the folic acid semi-finished products with the content higher than 35 percent and the folic acid finished products with the content higher than 98 percent can be obtained, and the defects of relatively low extraction rate and low extraction purity of the conventional method are overcome. The invention adopts the macroporous absorbent resin with the advantages of stable physicochemical property ...

Method for extracting tsukushinamine from lespedezadavurica of leguminous plants

The invention relates to a method for gathering tsukushinamine from purified lespedezadavurica by stage extraction, which belongs to the filed of natural organic chemistry. The invention is characterized in that: different from the former single process product, the stage extraction technique adopted by the invention divides an extractive into three sections to obtain three kinds of principle products according to different PH values, and comprehensively utilizes cash crop, thereby greatly improving the value of the cash crop; the product purity is high, wherein the tsukushinamine purity reaches 99.5%, the raspi alkali purity reaches more than 99%, and the nigerin alkali purity can reach 99%, thereby reaching officinal requirements or being capable of preparing officinal extractive; the extraction ratio is improved; and the production steps are simple, the bio-enzymolysis technology and the ultrasonic technology are adopted to partially resolve plant cell walls, thus the filtration speed ...

Method for measuring multi-gas partial pressure by using magnetic suspension rotor gauge

The invention relates to a method for utilizing spinning rotor gauge to measure gas partial pressure, which induces the gas of different components into a vacuum chamber and utilizes the characteristic that the relative attenuation rates of a spinning rotor gauge caused by different gases are independent from each other, comprising: when the vacuum chamber reaches ultimate vacuum, inducing a first gas path into the vacuum chamber, when the vacuum chamber is balanced, measuring the attenuation rate (-omega/omega) of the rotor, inducing a second gas path into the vacuum chamber, measuring the attenuation rate (-omega/omega) of the rotor caused by the two gases, subtracting (-omega/omega) from (-omega/omega) to attain the attenuation rate of the rotor caused by the second gas, similarly, inducing the n-th gas into the vacuum chamber, and when the vacuum chamber is balanced, measuring the attenuation rate (-omega/omega) of the rotor caused by n gases, and subtracting (-omega/omega) from (-omega ...

Converter mud based particle electrode and preparation method thereof

The invention relates to a converter mud based particle electrode of a three-dimensional electrode reactor and a preparation method thereof, the converter mud based particle electrode comprises converter mud, shale, a pore forming agent and an activating agent, dry fine converter mud particles are 50-60% by weight, dry fine shale is 10-20% by weight, the pore forming agent is 10-20% by weight, and the activating agent is 10-20% by weight. The converter mud based particle electrode is porous, large in pore size, large in specific surface area, and strong in adsorption, conductivity and catalytic activity, and is a new and efficient particle electrode. When the converter mud based particle electrode is used in waste water treatment, organic matters can be quickly decomposed into small molecular organic matters or completely mineralized, the COD (chemical oxygen demand) removal rate is higher than 90%, and the biodegradability of wastewater can be improved, According to the converter mud based ...

Music recommendation method and system

The invention relates to a music recommendation method which comprises the following steps of: acquiring music playing records of a user; extracting music listened by the user recently from the music playing records; acquiring a music distance between music in a music bank and the music listened by the user recently; generating a first music recommendation list according to the music distance. Since music in the first music recommendation list has high similarity with the music listened by the user recently and more accords with the habit of the user, the accuracy of music recommendation can be improved. The invention also provides a music recommendation system.

Preparation of modified polyacrylonitrile fibre

The invention relates to a preparation method of a modified polyacrylonitrile fiber, comprising the steps of: 1. blending starch and polyacrylonitrile according to the mass ratio of (5 to 50) : (95 to 50), dissolving the mixture in dimethyl sulfoxide solvent with the mass of 3 to 5 times of the total mass of the starch and the polyacrylonitrile, and stirring and evenly mixing at the temperature of 40 to 80 DEG C for 3 to 8h to prepare blending spinning solution; or firstly dissolving the starch and the polyacrylonitrile in own solvent respectively, then blending according to the mass ratio (5 to 50) : (95 to 50), and stirring and evenly mixing at the temperature of 40 to 80 DEG C for 3 to 8h to prepare the blending spinning solution; the starch solvent is dimethyl sulfoxide and the polyacrylonitrile solvent is one of dimethyl formamide and dimethyl acetamide, or mixture of a plurality of dimethyl formamide, dimethyl acetamide and dimethyl sulfoxide according to an arbitrary proportion; ...

Method for reducing weight-based charging errors caused by illegal weighing of trucks

The invention relates to a method for reducing weight-based charging errors caused by illegal weighing of trucks, which is characterized in that deceleration belts are arranged in front and back of a weighing platform at a weight-based toll gate of a freeway respectively, and by taking the lateral axis of the weighing platform as the reference, the distance between the deceleration belts arranged in front and back of the weighing platform and the weighing platform are arranged in accordance with distance between the front shaft and the rear shaft of a truck. Compared with the prior art, the method for reducing the weight-based charging errors caused by illegal weighing of trucks has the following benefits that the purpose of weight reduction of the truck undergoing illegal weighing cannot be achieved when the truck passes through the weighing platform on the freeway, therefore, tremendous loss of tens of billions of yuan of freeway toll in China caused by illegal weighing of trucks can ...

Substrate, preparation method thereof and light emitting diode

The invention provides a substrate, a preparation method thereof and a light emitting diode, and belongs to the technical field of photoelectron manufacturing. The substrate is provided with a bearing surface and a light emitting surface which are opposite to each other, the bearing surface is provided with a plurality of grooves, and each groove is filled with a reflection structure for reflecting light. According to the invention, the reflection path of light in the substrate can be effectively shortened, so that less energy is consumed when the light is propagated in the substrate, and the brightness of the light-emitting diode is improved.

MODIFIED FILLER COMPOSITION AND PAPERMAKING PROCESS USING THE SAME

A modified filler composition used in papermaking is provided. The modified filler composition contains microfibrillated cellulose, filler, and latex having a glass transition temperature of less than 20° C. The dry weight of the microfibrillated cellulose is about 0.1% to about 10% that of the filler; the dry weight of the latex is about 0.1% to about 15% that of the filler.

Method for Operating a High Density Multi-Level Cell Non-Volatile Flash Memory Device

A localized trapping multi-level memory cell operating method includes the following steps. First, a localized trapping memory cell with the initial threshold voltage of ˜2.5V is provided. Next, an erasing operation is performed to obtain a negative threshold level which has the uniform distribution along the channel region. Taking into account the over-erasure issue in the erasing course, a programming operation is performed to precisely adjust the threshold voltage to a predetermined level of −2V˜−1V. Then, with the negative voltage as a new initial state, corresponding programming operation is performed and electrons are locally injected the storage layer. By controlling the quantity of injected electrons, the MLC storage is achieved. 1. A Method for operating a high density multi-level cell non-volatile flash memory possesses the following operating steps:(a) a localized trapping memory cell with initial threshold voltage of about 2 V˜3 V is erased to a new initial level of about −2 V˜−1 V, after erasing, stored bits at each side of a cell have a same threshold level, and a uniform charge distribution in a nitride layer along the channel is obtained;(b) with the state of the negative threshold voltage of about −2 V−˜1 V as a new initial state, a MLC programming operation for the localized trapping memory is performed, a channel hot electron CHE injection is used with a positive substrate bias to suppress a secondary electron injection, or a pulse agitated substrate hot electron injection (PASHEI) programming method to implement the charge localized storage;(c) By changing a gate or a drain voltage or a programming time, more than eight programming states, i.e. more than eight threshold voltage levels can be achieved.2. The method according to claim 1 , wherein the step (a) is performed by a double-side band-to-band tunneling hot hole (BBHH) erasing method claim 1 , i.e. two equal positive voltages are applied on a source and the drain simultaneously claim 1 , ...

LYOPHILISIERBARES CONTRAST MEANS, GAS-FILLED MICRO VESICLE CONTAINING

Automatic liquid injection system and method

Method of making suspensions of air or gas filled microbubbles

Administrable compositions and methods for magnetic resonance imaging

Benzylic glycoside derivatives and methods of use

Benzylbenzene derivatives and methods of use

Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.

Targeted delivery of biologically active media

DEUTERATED 2,3,4-TRIHYDROXY-TETRAHYDROPYRANYL-BENZYLBENZENE COMPOUNDS HAVING SODIUM GLUCOSE COTRANSPORTER INHIBITORY ACTIVITY

Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions that are affected by SGLT inhibition.

Titanium metal sample metallurgical etching solution and etching method

The invention discloses a titanium metal sample metallurgical etching solution which is a mixed solution composed of concentrated nitric acid, hydrofluoric acid and distilled water in a volume ratio of 1:3:6, wherein the mass percent of the concentrated nitric acid is 65-68%, and the mass percent of the hydrofluoric acid is 47%. When the metallurgical etching solution and etching method are used for etching the titanium metal sample, a clear metallurgical structure can be observed under a metalloscope, and thus, the etching solution and etching method have favorable etching effect. The etching solution is prepared from the hydrofluoric acid and nitric acid, and thus, is low in cost.

Constant pressure type gas flowmeter transfiguration chamber

The invention relates to a varactor chamber of a constant voltage type gas flow indicator, belonging to the technical field of vacuum measurement. The varactor chamber comprises a pull rod, a bracket, a pin, a motion block, a bellows, a lead rail cylinder, a fixed block and a joint thereof; the main body of the varactor chamber of the constant voltage type gas flow indicator is a hydraulic thin wall forming bellows, the upper end of which is connected with the motion block and the lower end of which is connected with the fixed block; the motion block is connected with the pull rod by the pin, the pull rod pulls the motion block to move, the motion block compresses or stretches the bellows; the pull rod penetrates through a through hole in the center of the bracket; the lead rail cylinder is arranged in the bellows and is welded at one end of the fixed block, the other end of the fixed block is connected with the joint. The hydraulic thin wall forming bellows is made by stainless steel materials ...

Improvement oral medicine medicine glass

The utility model relates to an improvement oral medicine medicine glass, it includes two above cups and bowl cover, bowl cover shape and cup correspond, two above cup tight fit superpose become integrative, the cup is the well short side body, and it is narrow down to go up the width, has the pattern draft, the inboard a pair of above opposite face of cup is equipped with a spacing post respectively, spacing post upwards prolongs from cup bottom and rises the middle part, and the top of all spacing posts is on same horizontal plane, and superpose cup bottom is on it supported on the spacing post of pressing cup below, perhaps a pair of above opposite face in the cup outside is equipped with a spacing post respectively, spacing post rises the middle part from cup cover groove lower part to the decurrence, and the bottom of all spacing posts is on same horizontal plane, and the spacing toe portion of superpose cup on it supports on the cover groove who presses cup below, cup outer wall top ...

Traditional Chinese medicine for treating diabetes and hyperlipidemia

The invention discloses a drug for treating diabetes and hyperlipidemia, in particular to the drug which takes Chinese herbal medicines as a formula for treating diabetes and hyperlipidemia. The invention adopts the following technical proposal: a traditional Chinese medicine for treating diabetes and hyperlipidemia takes gynura root as a monarch drug and takes gynostemma pentaphyllum as a minister drug, the dose is 2.8-3.3: 1 by weight percentage for compatibility, and the optimal formula is that the dose of the gynura root and the gynostemma pentaphyllum is 3: 1 by weight percentage for compatibility. The drug has great effects for more than 80 percent of patients with type II diabetes and significant effects for preventing and treating a variety of complications caused in late stage ofthe diabetes; the effects for the patients with high blood sugar and hyperlipidemia are even better, and more than 80 percent of people do not need to take any other drug.

Surface aging treatment process of enhancing high manganese steel initial wear-resisting performance

Nucleic acid sample processing method, sequencing method and kit

The invention provides a DNA sample processing method, a sequencing method and a kit. The method for treating the DNA sample comprises the following steps: carrying out fragmentation, terminal repairing and dA tail adding treatment on DNA in a first premixing system to obtain a first product; the first pre-mixing system comprises a pre-mixing enzyme, and the pre-mixing enzyme comprises a DNA fragmentation enzyme, a polynucleotide kinase and a DNA polymerase. Based on a test experiment and an optimized mixed enzyme system, various enzymes are mixed in the same reaction system, DNA breakage, terminal repair and dA tail addition are realized in one step, the method is simple, convenient and rapid, the operation time of sample treatment before loading is saved, and industrialization is facilitated.

THE LITTLE MOLECULE COMPOUND WHICH USED FOR PROMOTING THE STEM CELLS HYPERPLASIA AND THE USE THEREOF

The invention provides small molecule compounds capable of accelerating proliferation of stem cells and uses thereof. The compounds play an important role in the research of stem cell proliferation mechanism. The invention further relates to the uses of the compounds and relevant compounds thereof in the preparation of stem cell proliferation accelerators and the preparation of medicines accelerating stem cell proliferation. The invention also relates to the uses of the compounds in the preparation of medicines for the treatment of various diseases arising from functional cells loss or damage. The diseases arising from stem cell trauma comprise diseases related to the degeneration or damage of nervous system cells, blood system diseases, diseases related to the loss or damage of cardiovascular cells, skin burn and the like.

QUATERNARY LACTAM COMPOUND AND PHARMACEUTICAL USE THEREOF

A quaternary lactam compound of formula (I). The compound is used in the manufacture of a medicament for the treatment and/or prevention of thrombotic or thromboembolic disorders. 3. The compound of claim 1 , wherein Ris selected from the group consisting of hydrogen claim 1 , halogen claim 1 , Calkyl claim 1 , Calkoxy claim 1 , Ccycloalkyl claim 1 , Ccycloalkyloxy claim 1 , aryl claim 1 , —(CH)NRR claim 1 , —COR claim 1 , —COOR claim 1 , —C(O)(CH)NRR claim 1 , —(CH)NHC(O)Calkyl claim 1 , —NHC(O)(CH)C(O)Calkyl claim 1 , —S(O)(CH)NRR claim 1 , —NH(CH)S(O)R claim 1 , —SR claim 1 , —(CH)CN claim 1 , and —O(CH)NRR;preferably, A is aryl or heteroaryl;{'sup': 2', '6', '7', '6', '7', '5a', '5b', '6', '7', '5a, 'sub': 2', 't', '2', 'n', '2', 't', '2', 't', '2', 't', '2', 't', 'm', '2', 't', 'm', '2', 't', 'm', '2', 't', '2', 't', 'm, 'preferably, Ris selected from the group consisting of —(CH)X(CH)NRR, —(CH)CN, —(CH)NRR, —(CH)COR, —(CH)COOR, —C(O)(CH)NRR, —C(O)(CH)aryl, —C(O)(CH)heteroaryl, —CONH(CH)heterocyclyl, and —CONHS(O)R;'}preferably, X is O;preferably, each n is the same or different and is independently an integer of 1, 2, 3, 4, 5, 6, 7, 8, 9 or 10;preferably, each m is the same or different and is independently an integer of 1 or 2;preferably, each t is the same or different and is independently an integer of 0, 1, 2, 3, 4, 5, 6, 7, 8, 9 or 10;{'sup': '5a', 'sub': 1-4', '1-4', '3-6, 'preferably, each Ris the same or different and is independently selected from the group consisting of hydrogen, halogen, Calkyl, halogenated Calkyl, Ccycloalkyl, heterocyclyl, aryl, and heteroaryl;'}{'sup': 5b', '6', '7, 'sub': 1-4', '1-4', '3-6, 'preferably, R, Rand Rare the same or different and are independently selected from the group consisting of hydrogen, Calkyl, halogenated Calkyl, Ccycloalkyl, heterocyclyl, aryl, and heteroaryl.'}7. A pharmaceutical composition claim 1 , comprising at least one selected from the group consisting of the compound of formula (I) of claim 1 , the ...

Lyophilisierbares Kontrastmittel, gasgefüllte Mikrobläschen enthaltend

Grism optical system

A dispersion device 10 for use with a polychromatic beam has first and second identical transmissive grisms 11, 12 (prismatic grating) aligned back to back along optical axis 15 so their gratings 14 are opposite to, and face each other. A distance D separates the gratings 14. The distance D may be varied. A polychromatic beam sent along axis 15 are dispersed by the first grism 11 and collimated by the second grism 12 to provide a dispersed collimated output beam. The grisms 11,12 may be volume phase hologram grisms (21, 22, fig 2).

Method of storage of ultrasonic gas suspensions

DEUTERATED BENZYLBENZENE DERIVATIVES AND METHODS OF USE

Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions that are affected by SGLT inhibition.

BENZYLPHENYL CYCLOHEXANE DERIVATIVES AND METHODS OF USE

Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.

BENZYLBENZENE DERIVATIVES AND METHODS OF USE

Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.

Method for preparing aluminium based composite material enhanced by AlCuFe through extrusion casting method

A method of preparing AlCuFe Quasicrystalline Particles Reinforced Al base Composites. The present invention adopts the method of high pressure inert gases atomization to prepare the powder of AlCuFe. The Quasicrystalline Particles which is 20 - 100 micron after sift out, is heat treated in order to get single phase of Quasicrystalline Press it in cold, and then press it into prefabrication in the ratio of design. Heat preservation the prefabrication and die, and fusion the aluminium alloy at the same time. Press and penetrate it after heat preservation in order to prepare Quasicrystalline Particles Reinforced Al base Composites. The present invention has simple technics and low cost.

Method for preparing haemolytic sphingolipid by efficiently hydrolyzing sphingolipid

The invention discloses a method for preparing haemolytic sphingolipid by efficiently hydrolyzing sphingolipid. The method comprises the following steps: firstly modifying sphingolipid ceramide N-deacylated enzyme SCDase G8 for removing N-terminated signal peptide and truncating a terminal C to obtain a high-activity mutant SCDase G8-del of SCDase G8, and performing codon optimization on coding genes aiming at host cells; and improving the soluble expression quantity of SCDase G8-del by optimizing protein expression conditions. A method for preparing haemolytic sphingolipid by efficiently hydrolyzing sphingolipid by using SCDase G8-del is established based on the steps. By adopting the method disclosed by the invention, the soluble expression conditions of high-activity SCDase G8-del can be optimized, the concentration of metal ions in a reaction system can be optimized, the type and concentration of a surface active agent can be optimized, and the yield of haemolytic sphingolipid can be ...

Method for implementing master control board software upgrading by SLIP protocol

The invention discloses a method for realizing main control panel software updating by the SLIP protocol in the field of computer network communication technology. The technical proposal is as follows: an updating server is connected with the main control panel by a serial port through using a string line, updating software in the server is transmitted to the main control panel by the SLIP protocol so as to realize the software updating of the main control panel. The invention realizes the software updating of the main control panel by the SLIP protocol, thereby causing the main control panel to complete the network updating task under the condition that the network is limited, and leading the cost of realizing the network updating of the main control panel to be greatly lowered.

Method and device for secondarily filtering doctor solution by side stream

The invention relates to a method and a device for secondarily filtering a doctor solution by side stream, and belongs to the technical field of purification of the doctor solution of synthesis ammonia. The method adopts a doctor solution side-stream filter process, and desulfurizes the doctor solution by a doctor solution side-stream filter system and a filter regeneration system which regenerates the filter system; and the device consists of the doctor solution side-stream filter system and the filter regeneration system. The invention is suitable for tannin extract normal pressure desulfurization systems; and after the doctor solution shunted on a doctor solution main pipeline is desulfurized by the device, suspending sulfur and secondary salt contents in deficient liquid after the desulfurization can be effectively reduced, and phenomenon of tower blockage of a desulfurizing tower is reduced. The method and the device not only improve the desulfurization efficiency of the tannin extract ...

Variable-volume chamber of constant pressure type positive pressure leak hole calibration device

The invention relates to a constant pressure type volume-varied chamber for pressure leak calibration devices, which comprises a nut, a pipe, a volume-varied chamber body, a volume-varied chamber inner hole, a piston ferrule joint, an inner hole channel and a baffle plate, wherein an exhaust unit adopts a four-way joint to evacuate the volume-varied chamber inner hole, the inner hole channel and the pipe; a gas bottle charges nitrogen gas of one atmospheric pressure into the chamber via a four-way joint; the gas leaked from the pressure leak flows into the volume-varied chamber body, the inner hole channel and the pipe via a three-way joint, to cause pressure increase, while the increased value is measured by a pressure differential capacitor film gauge; according to the measurement data of the pressure differential capacitor film gauge, a piston is controlled to move, the motion speed, motion distance and the sectional area of the piston and the gas pressure in the volume-varied chamber ...

Nano fracturing process with function of desorption acceleration

The invention belongs to fields of underground energy development, reserve increase, yield increase and reservoir modification and discloses a nano fracturing process with a function of desorption acceleration. The nano fracturing process includes: removing well incrustations by well flushing, sequentially dissolving fracturing fluid CFs, liquid-state retardant acid CArL, stratum authigenic latent acid CAP, solid-state retardant acid CArS and acidic viscoelastic cleaning foam fracturing fluid VCFa, performing acidic sand fracturing, breaking viscosity, flowing back, communicating and broadening nano apertures. Network cracks in nano size, micron size, millimeter size and centimeter size can be constructed efficiently with low cost while desorption speed, diffusion rate and seepage velocity are increased, industrial exploitation of compact oil gas, adsorption oil (shale oil) and adsorption gas (coalbed methane and shale gas) in nano pores can be realized, and industrial power generation ...

Matériau composite hémocompatible.

L'invention a pour objet un matériau composite comprenant une membrane-support revêtue d'un additif réduisant le caractère thrombogène du support. La membrane support est constituée essentiellement par un copolymère d'acrylonitrile et d'au moins un monomère d'acrylonitrile dont l'un au moins des comonomères comprend le motif polyoxyéthylène; cet additif peut en outre comprendre un monomère chargé positivement, tel qu'un ammonium quaternaire. Le matériau composite de l'invention peut être utilisé pour le traitement du sang, notamment pour la dialyse et la plasmaphérèse.

Deuterated benzylbenzene derivatives and methods of use

Method and apparatus for automatic cross-system program debugging

The present invention discloses a method and apparatus for automatic cross-system program debugging. One embodiment of the present invention provides a method for cross-system program debugging. The method comprises: determining a first breakpoint in a first debugging session of a first system; determining a second breakpoint in a second debugging session of a second system, the second system being different from the first system; and responsive to a user performing a debugging action of associating the first breakpoint with the second breakpoint in the first debugging session and the second debugging session, recording an association between the first breakpoint and the second breakpoint for automating the program debugging across the first system and the second system. There is further described a corresponding apparatus.

Detection of molecular interactions using field effect transistors (FETs)

A sensor for use in the detection of a molecular interaction comprises a field effect transistor (FET) having a core structure and an extended gate structure, the core structure and the extended gate structure being located on substantially separate regions of a substrate, the extended gate structure including an exposed metal sensor electrode on which probe molecules can be immobilized, wherein, in use, the sensor is operative to produce a change in an electrical characteristic of the FET in response to molecular interaction at the exposed surface of the metal sensor electrode. The sensor is particularly suitable for detecting biomolecular interactions such as the hybridization of DNA, when the sensor is prepared with suitable probe molecules immobilized on the exposed gate metal.

Compounds that maintain pluripotency of embryonic stem cells

Gas-filled microvesicles with polymer-modified lipids

Deuterated benzylbenzene derivatives and methods of use

Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions that are affected by SGLT inhibition.

Benzylphenyl cyclohexane derivatives and methods of use

Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.

Compound and use thereof in synthesis of brivaracetam intermediate and crude drug

The present application provides a compound in formula III, and further provides a use of the compound in the synthesis of a Brivaracetam intermediate and a crude drug, and a synthesis method. A raw material involved in the method of the present application is low in costs and easily available; (R)-4-propyl-dihydrofuran-2-ketone having high optical purity can be prepared; complicated separation and purification steps are avoided; costs are reduced, and the method is more applicable to industrial production.

Compound and use thereof in synthesis of brivaracetam intermediate and crude drug

The present application provides a compound in formula III, and further provides a use of the compound in the synthesis of a Brivaracetam intermediate and a crude drug, and a synthesis method. A raw material involved in the method of the present application is low in costs and easily available; (R)-4-propyl-dihydrofuran-2-ketone having high optical purity can be prepared; complicated separation and purification steps are avoided; costs are reduced, and the method is more applicable to industrial production.

Method of storage of ultrasonic gas suspensions

SHAPE SHIFTING HAMPER AND BAG

A container takes on the form of a laundry hamper or basket while static or stationary. Upon bringing front and back panels of the container into closer proximity for transport, such as by drawing together their respective handles, or drawing one of the handles towards the other, the container changes configuration, or shape, to that of a tote bag. Upon releasing at least one of the front and back panels of the container from being drawn towards the other, such as by releasing at least one of their respective handles, the container automatically reverts back to the form of a laundry hamper or basket. The use of substantially rigid front and back panels, coupled with side panels that have resilient upper regions, permit the side panels to take on a spout-like configuration when the container is in its tote bag configuration, and to return to a planar configuration when the container is in its laundry hamper or basket configuration.

Traditional Chinese medicine for treating diabetes and hyperlipidemia

The invention discloses a drug for treating diabetes and hyperlipidemia, in particular to the drug which takes Chinese herbal medicines as a formula for treating diabetes and hyperlipidemia. The invention adopts the following technical proposal: a traditional Chinese medicine for treating diabetes and hyperlipidemia takes gynura root as a monarch drug and takes gynostemma pentaphyllum as a minister drug, the dose is 2.8-3.3: 1 by weight percentage for compatibility, and the optimal formula is that the dose of the gynura root and the gynostemma pentaphyllum is 3: 1 by weight percentage for compatibility. The drug has great effects for more than 80 percent of patients with type II diabetes and significant effects for preventing and treating a variety of complications caused in late stage of the diabetes; the effects for the patients with high blood sugar and hyperlipidemia are even better, and more than 80 percent of people do not need to take any other drug.

Expression of Hypoderm A (HA) in pastoris system and use thereof

The invention discloses the expression of cattle dermatobia element in the pichia system and its application. The yeast expression carrier in the invention is pPIC9k-HA, the pichia bacterial converted by expression carrier that can express A(HA) is GS115/pPIC9k-HA. The method for preparing A(HA) with GS115/pPIC9k-HA comprises: firstly carrying out cell culture and protein evoked secret; then purifying the expression product. The invention is characterized in that: expressing the cattle dermatobia element A protein by using pichia, separating and purifying HA by means of FPLC anion exchange chromatography, which is a cheap and high productive method, and pichia can use the carbon in the culture medium and duplicate the DNA in the genome steadily, by applying continuous cultivation with high density can increase protein yield, and the advantage of the invention includes the simple, convenient and cheap pronucleus expression system besides the modification function after the translation which ...

Molten iron catalyst prepared from blast furnace dust for ammonia industrial synthesis

The present invention relates to the field of environmental technology, and specifically relates to a molten iron catalyst prepared from blast furnace dust for ammonia industrial synthesis. The catalyst comprises an iron oxide Fe3O4 as a main ingredient, and cobalt oxide, potassium oxide and alumina as accelerators. The ratio of ferrous iron to ferric iron in the catalyst is controlled between 0.45 and 0.60, and the catalyst is prepared by a melting method. Preparing the molten iron catalyst by utilizing blast furnace dust for ammonia industrial synthesis not only improves recycling efficiency, but also effectively opens up a new way for reducing the blast furnace dust and turning the blast furnace dust to resources. The present molten iron catalyst for industrial ammonia synthesis uses the blast furnace dust as the main raw material. The product performance can meet industry standards, and conform to current China's economic development policies, "recycling economy, energy conservation ...

Heat-treatment method for magnesium power cell anode sheet material

The invention discloses a heat treatment method of a magnesium-powered battery anode plate. The method adopts flowing cold air quenching and multiple anisothermal annealing. Specifically the method comprises the following steps: step 1. solution treatment at 648-688K, holding for 22-25h, and adopting the flowing cold air quenching; step 2. process annealing in the rolling process at 653-688K for 0.3-1.2h; step 3. annealing at 433-488K for 6-10h. The method ensures that a magnesium anode material can be rolled into plates with thickness of 0.1mm without cracking, which greatly thins the magnesium alloy plate. The heat treatment method causes the grains of the magnesium alloy anode plate to be small, greatly lowers the self-corrosion rate, and controls generation of a cathodic second phase compound that is helpful for the electrochemical activity, and leads the compound to be evenly distributed in grains.

Folding mechanism of plane working ladder

The invention relates to the technical field of plane ground maintenance equipment, in particular to a folding mechanism of a plane ground maintenance working ladder. The folding mechanism of the plane working ladder is high in strength, high in rigidity, long in service life, easy to operate and capable of bearing a heavy load, and is a box-shaped part composed of an inner side supporting arm (1), a limiting stop block (2), a starting lock buckle (3), an outer side supporting arm (4), a supporting mechanism (5) and a limiting mechanism (6), wherein an end socket of one end of the inner side supporting arm (1) and an end socket of one end of the outer side supporting arm (4) are round thin walls. The structural strength is largely improved, and the folding mechanism of the plane working ladder is capable of bearing the heavy load and long in service life.

Core rod of insulator and manufacturing method thereof

The invention discloses a core rod of an insulator, comprising a hollow rod body and a plurality of partition blocks, wherein the hollow rod body is compounded by ethoxyline resins and glass fibres; the partition blocks are vertically embedded into the hollow rod body in the hollow rod body and can be all in a light disk shape, or the partition blocks close to both ends of the hollow rod body arein a light disk shape, and other partition blocks are in a light disk shape or a shape that both end surfaces of the light disk are provided with bevel teeth. A manufacturing method of the core rod comprises the following steps: (a) manufacturing the partition blocks, i.e. manufacturing the partition blocks according to the requirement of the core rod which needs to be manufactured; (b) manufacturing a base pipe, i.e. manufacturing the base pipe in a squeezing and pulling way; (c) cutting, i.e. cutting the base pipe on a position needing to install the partition blocks; (d) fixing, i.e. placing ...

Method for measuring volume change of volume-changeable chamber bellows of constant pressure type gas flow meter

The invention discloses a method for measuring volume change of a constant pressure gas flowmeter bellows, belonging to the technical field of vacuum measurement; by adopting the isothermal expansion principle of gas, the method comprises the following steps: firstly filling gas with known pressure into a variable capacitance chamber; filling the gas into a standard container to measure the volume of the variable capacitance chamber when the bellows is in a natural state; then filling the gas into the bellows in natural state in the variable capacitance chamber and compressing the bellows to change the volume of the bellows and increase the pressure in the variable capacitance chamber to finally measure the volume change of the bellows. The method avoids using water medium for measurement, as well as such processing as degasing, baking and the like after the measurement but before the use of the variable capacitance chamber and bellows. The measuring process is simple and easy, dismounting ...

Small molecule compound being capable of promoting proliferation of stem cells and function thereof

The invention provides a small molecule compound capable of accelerating proliferation of stem cells and a function thereof. The compound plays an important role in the research of stem cell proliferation mechanism. The invention further relates to the function of the compound and relevant compounds thereof in the preparation of stem cell proliferation accelerators and the preparation of medicines accelerating stem cell proliferation. The invention also relates to the function of the compound in the preparation of medicines for treating various diseases arising from stem cell trauma. The diseases arising from stem cell trauma comprise diseases related to the retrogression or traumatism of nervous system cells, blood system diseases, diseases related to the loss or traumatism of cardiovascular system cells, skin burn and the like.

Inorganic oxidability high molecular ferro-silicon coagulant, preparation process thereof and applications

The present invention provides an inorganic oxidizing macromolecular silicon iron coagulating agent, a preparation technique thereof and the application to water treatment. The coagulating agent is yellowish green or yellowish brown liquid or solid product, has low cost, good stability and oxidizing property and increases composite function and improves efficiency for eliminating turbidity, color, heavy metals, algae, organic matter, etc. The UV254 removal rate of the water of the Yellow River can reach 55%-80%, and the COD Mn removal rate can reach 75%-95%. For slaughtering wastewater, COD can drop below 100mg/L, and chroma is lowered below 5 and phosphorus removal rate can reach 80%-98%. The preparation method of the coagulating agent adopts an oxidation and copolymerization method, has simple technique and equipment, short period and no secondary pollution and can be carried out at normal pressure and low temperature. The inorganic oxidizing macromolecular silicon iron coagulating agent ...

Fast image processing method for high definition camera

The invention provides a fast image processing method for a high-definition camera, which pertains to the field of image processing and comprises the steps of firstly defining and generating a bit adaptive mapping table, an RGB color mapping table and a brightness mapping table; then carrying out statistics to the color and brightness information of the image, determining regulatory factor and brightness of R/G/B, and amending the RGB color mapping table and the brightness mapping table; and then converting the collected image, carrying out R/G/B color mapping, mosaic removing, format conversion and brightness mapping, carrying out filtration to the brightness according to the expected indexes, and generating YCbCr data stream; finally converting the image to a JPEG image for conservationor transmission. The method uses fast table search processing, occupies small resources, is applicable to development of embedded systems, realizes necessary image processing functions, finishes the processing ...

Signal read-out amplifying method of photosensitive compound medium grid MOSFET detector

The invention relates to a signal read-out amplifying method of a photosensitive compound medium grid MOSFET detector, comprising the following steps of: setting N-type semiconductor regions at both sides above a P-type semiconductor material of a substrate to form a source electrode and a drain electrode, setting a bottom-layer and top-layer insulting medium material and grid above the substrateas well as a photosensitive compound medium grid MOSFET detector of a photoelectron storage layer; reading out and amplifying the photoelectron, i.e., grounding the source electrode of the detector and the substrate, connecting the drain electrode at a positive voltage of about 0.1V, and enabling the MOSFET detector to operate in a linear region by adjusting the grid voltage of about 1-3V; directly measuring the output drain current to obtain the relation of the current variation of the drain electrode and the number of the searched photoelectron i.e., biasing VG on the grid of the detector and ...

Attendance statistics control method and related equipment

The invention discloses an attendance statistics control method and related equipment, relates to the field of attendance punching, and mainly aims to solve the problem that a more intelligent attendance punching supervision control method is still lacked at present. The method comprises the following steps: acquiring actual attendance clock-in time and a specified clock-in time period of a target user; under the condition that the actual attendance clock-in time is within a specified clock-in time period, storing a clock-in result of the target user in a target storage unit of the local end; and under the condition that the current system time is in the non-specified clock-in time period, uploading the clock-in result to a cloud server. The method is used for the attendance statistics control process.

Heteroaryl compounds as kinase inhibitor

Provided herein are heteroaryl compounds of formula (I) having activity on a receptor protein tyrosine kinase, wherein R ...

Toothbrush and method for making a tuft of bristles usable in a toothbrush

Deuterated benzylbenzene derivatives and methods of use

VACUUM FITTING CONNECTION

Additive for dye-sensitized solar cell

The invention discloses an additive for a dye-sensitized solar cell. The additive for the dye-sensitized solar cell is a pyridine ionic liquid additive, the chemical structure general formula of the additive is shown in the claims or a pyridine ionic liquid provided by the invention can be used for the additive for a dye-sensitized solar cell electrolyte. The ionic liquid additive has the advantages of simpleness in synthesis steps, convenience for preservation, no environmental pollution and difficulty in volatilization and leakage. The cell formed by taking the ionic liquid provided by the invention as the additive has better performance and higher stability.

TRANSMITTING SYSTEM AND METHOD THEREOF

A datagram transmitting system includes a server and a client. The client includes a first transmitting module and a detecting module. The server includes a management module and a second transmitting module. The detecting module detects whether network congestion and generates a status signal. If network is congested, the detecting module generates a first status signal. The first transmitting module transmits the status signal to the management module. The management module packages a first predetermined length of data into a datagram responding to the first status signal. The first predetermined signal is at most 65,507 bytes but more than 0 bytes in length. The second transmitting module transmits the datagram to the first transmitting module. 1. A datagram transmitting system for transmitting datagram between a server and a client , the datagram transmitting system comprising:the server comprising at least one processor, a storage system and one or more programs, the one or more programs stored in the storage system, executable by the at least one processor;the client comprising at least one processor, a storage system and one or more programs, the one or more programs in stored in the storage system, executable by the at least one processor,the one or more programs comprising:a detecting module adapted to detect network congestion and generate a status signal, if network is congested the detecting module generates a first status signal;a first transmitting module adapted to transmit the first status signal;a management module adapted to package a first predetermined length of data into a datagram responding to the first status signal, the first predetermined length is at most the longest length of a transmitting protocol and more than 0 bytes; anda second transmitting module adapted to transmit the datagram to the first transmitting module in the server.2. The datagram transmitting system of claim 1 , wherein the first transmitting module and the detecting ...

PHOSPHODIESTERASE INHIBITORS AND USES THEREOF

The invention provides for compounds that are phosphodiesterase inhibitors. The invention further provides for a method for screening compounds that bind to and modulate a phosphosdiesterase protein. The invention also provides methods for treating conditions associated with accumulated amyloid-beta peptide deposit accumulations by administering a phosphodiesterase-binding compound to a subject. 2. The compound of claim 1 , wherein A is N.3. The compound of claim 1 , wherein Ris hydrogen.4. The compound of claim 1 , wherein Ris —OCH.6. The compound of claim 5 , wherein Ris CH.8. The compound of claim 1 , wherein Ris CH—OH.9. The compound of claim 1 , wherein Ris H.10. The compound of claim 1 , wherein Ris a halogen.11. The compound of claim 1 , wherein Ris chlorine.12. The compound of claim 1 , wherein Ris —CN.13. The compound of claim 1 , wherein Ris a halogen.14. The compound of claim 1 , wherein Ris fluorine.16. The compound of claim 1 , wherein Ris hydrogen.17. The compound of claim 1 , wherein Ris C-Ccycloalkyl claim 1 , —NRR claim 1 , or —SR.18. The compound of claim 1 , wherein Ris C-Ccycloalkyl or —NRR.19. The compound of claim 1 , wherein Ris —NRR.20. The compound of claim 1 , wherein Ris —NRR claim 1 , and wherein Rand Rare each independently hydrogen claim 1 , —C-Calkyl claim 1 , —C-Ccycloalkyl claim 1 , or —C(O)R claim 1 , wherein the C-Calkyl or C-Ccycloalkyl are optionally substituted with C-Calkyl claim 1 , —C-Ccycloalkyl claim 1 , or —NRR; or claim 1 , Rand Rtogether with the nitrogen atom to which they are attached form a 3 to 8-membered heterocycle claim 1 , wherein any one of the ring carbon atoms is optionally replaced with O claim 1 , NRor N—C(O)R.21. The compound of claim 1 , wherein Ris —SR.22. The compound of claim 1 , wherein Ris —S—(C-C)-alkyl.23. The compound of claim 1 , wherein Ris C-Ccycloalkyl.24. The compound of claim 1 , wherein Ris cyclopropyl.25. The compound of claim 1 , wherein Ris dimethylamino.28. A method for screening ...

ULTRASOUND CONTRAST AGENTS AND METHODS OF MAKING AND USING THEM

The invention is directed to injectable suspensions of gas-filled microvesicles, as well as methods of preparing and using the same, especially as ultrasound contrast agents. 1. A composition suitable for injection into the bloodstream and body cavities of living beings , comprising a suspension of stabilized air or gas microbubbles in a physiologically acceptable aqueous carrier phase having one or more dissolved or dispersed surfactants , at least one of said surfactants being a film forming saturated phospholipid present in the composition at least partially in lamellar or laminar form. wherein at least one of said surfactants comprise , bound thereto , bioactive species designed for specific targeting purposes.2. A composition suitable for injection into the bloodstream and body cavities of living beings , comprising a suspension of air or gas microbubbles in a physiologically acceptable aqueous carrier phase stabilized having one or more dissolved or dispersed surfactants , at least one of said surfactants being a film forming saturated phospholipid present in the composition at least partially in lamellar or laminar form , said surfactants forming a surfactant layer stabilizing said microbubbles , wherein monoclonal antibodies tailored by genetic engineering , antibody fragments or polypeptides designed to mimic antibodies , bioadhesive polymers , lectins or other site-recognizing molecules are bound to the surfactant layer.3. The composition of any one of or , wherein the suspension contains at least 10microbubbles per milliliter and wherein the concentration of the phospholipid(s) in the liquid carrier is below 0.01% by weight.4. The composition of claim 1 , in which the concentration of microbubbles per milliliter is between 10and 10.5. The composition of claim 3 , in which the concentration of phospholipids is above 0.00013% wt.6. The composition of claim 1 , in which the liquid carrier further comprises a stabilizer selected from the group consisting of ...

Parallel Processing Of Data Sets

Systems, methods, and devices are described for implementing learning algorithms on data sets. A data set may be partitioned into a plurality of data partitions that may be distributed to two or more processors, such as a graphics processing unit. The data partitions may be processed in parallel by each of the processors to determine local counts associated with the data partitions. The local counts may then be aggregated to form a global count that reflects the local counts for the data set. The partitioning may be performed by a data partition algorithm and the processing and the aggregating may be performed by a parallel collapsed Gibbs sampling (CGS) algorithm and/or a parallel collapsed variational Bayesian (CVB) algorithm. In addition, the CGS and/or the CVB algorithms may be associated with the data partition algorithm and may be parallelized to train a latent Dirichlet allocation model.

RADIO FREQUENCY FRONT-END CIRCUIT FOR WIRELESS COMMUNICATION DEVICE

A radio frequency (RF) front-end circuit includes a multiband antenna, an antenna switch, a duplexer, a communication mode selection switch, and a processor. The processor selectively connects the antenna switch or the duplexer to the multiband antenna using the communication mode selection switch. When the multiband antenna is connected to the antenna switch, the processor directs the antenna switch to transmit wireless signals used in a first wireless communication system received by or sent from the multiband antenna; when the multiband antenna is connected to the duplexer, the duplexer transmits wireless signals used in a second wireless communication system received by or sent from the multiband antenna. 1. A radio frequency (RF) front-end circuit , comprising:a multiband antenna;an antenna switch;a duplexer;a communication mode selection switch connected to the multiband antenna, the antenna switch, and the duplexer; anda processor that controls the communication mode selection switch to selectively connect the antenna switch or the duplexer to the multiband antenna; wherein when the multiband antenna is connected to the antenna switch, the processor controls the antenna switch to transmit wireless signals used in a first wireless communication system received by or sent from the multiband antenna; and when the multiband antenna is connected to the duplexer, the duplexer transmits wireless signals used in a second wireless communication system received by or sent from the multiband antenna.2. The RF front-end circuit as claimed in claim 1 , wherein the wireless signals used in the first communication system are GSM signals in a plurality of GSM frequency bands claim 1 , and the wireless signals used in the second communication system are UMTS signals in a predetermined UMTS frequency band.3. The RF front-end circuit as claimed in claim 2 , wherein the processor controls the antenna switch to transmit GSM signals received by or sent from the multiband antenna ...

Non-Invasive Glucose Sensor

A non-invasive glucose sensor () for detecting an amount of glucose in bodily fluid, comprising: an organic electrochemical transistor (OECT) having a gate electrode (); wherein a surface of the gate electrode () is modified with an enzyme and a nanomaterial to increase sensitivity and selectivity of the gate electrode (). 1. A non-invasive glucose sensor for detecting an amount of glucose in bodily fluid , comprising:an organic electrochemical transistor (OECT) having a gate electrode;wherein a surface of the gate electrode is modified with an enzyme and a nanomaterial to increase sensitivity and selectivity of the gate electrode.2. The sensor according to claim 1 , wherein the gate electrode is a Pt gate electrode.3. The sensor according to claim 1 , wherein the enzyme is glucose oxidase (GOx).4. The sensor according to claim 1 , wherein the nanomaterial is any one from the group consisting of: multi-walled carbon nanotubes (MWCNTs) and platinum nanoparticles (Pt-NPs).5. The sensor according to claim 1 , wherein the bodily fluid is any one from the group consisting of: saliva claim 1 , tissue fluid claim 1 , sweat and aqueous humor.6. The sensor according to claim 1 , wherein the gate electrode is composed of MWCNT-CHIT/GOx/Pt or CHIT/GOx/Pt-N Ps/Pt.7. A method for manufacturing a non-invasive glucose sensor for detecting an amount of glucose in bodily fluid claim 1 , the method comprising:drop coating a glucose oxidase (GOx) Phosphate Buffered Saline (PBS) solution onto a surface of a substrate to form a GOx/Pt electrode; anddrop coating a nanomaterial chitosan (CHIT) hybrid aqueous solution onto a surface of the GOx/Pt electrode after the GOx PBS solution has dried on the surface of the substrate.8. The method according to claim 7 , wherein the nanomaterial is any one from the group consisting of: multi-walled carbon nanotubes (MWCNTs) and platinum nanoparticles (Pt-NPs).9. A method for detecting an amount of glucose in bodily fluid claim 7 , the method ...

Automatic Liquid Injection System and Method

A power assisted method and injector device for controllably delivering to patients a dispersion medicament or diagnostically active agent, the homogeneity of which is preserved throughout delivery. Diagnostically active agents disclosed are gas microbubble suspensions useful in ultrasonic diagnostic imaging and liposomal formulations in which liposome vesicles are loaded with iodinated compounds. 1. A method of administering to patients by injection or infusion a suspension of microparticles homogeneously distributed in an aqueous liquid carrier by means of an injector system comprising a syringe containing said suspension and a power driven piston for injecting said suspension into a patient , characterised by subjecting the suspension in the syringe to a rotation or rocking motion , thereby maintaining said suspension homogeneous by preventing segregation of the microparticles by gravity or buoyancy , this being without damaging said particles or disturbing their distribution.2. The method of claim 1 , in which said motion is provided by outside means for imparting motion to said particles claim 1 , which motion is then transferred to said liquid carrier.3. The method of claim 1 , in which said motion of rocking or rotation is alternated.4. The method of claim 3 , in which said motion is applied along or around the syringe longitudinal or transverse axis.5. The method of claim 4 , in which said motion is provided by subjecting the syringe to continuous or intermittent rotation.6. The method of claim 5 , in which the rotation rate is from 0.5 to 200 rpm.7. The method of anyone of preceding claims claim 5 , in which said motion is alternating rotation the direction of which is reversed every 30° claim 5 , 60° claim 5 , 90° claim 5 , 180° claim 5 , 270° or 360°.8. The method of claim 7 , in which the direction is alternated at a frequency of 0.5 Hz claim 7 , 1.0 claim 7 , Hz claim 7 , 1.5 Hz claim 7 , 2.0 Hz claim 7 , 2.5 Hz claim 7 , 3.0 Hz or 3.5 Hz.9. The method ...

Three-dimensional multi-bit non-volatile memory and method for manufacturing the same

The present disclosure relates to the field of microelectronics manufacture and memories. A three-dimensional multi-bit non-volatile memory and a method for manufacturing the same are disclosed. The memory comprises a plurality of memory cells constituting a memory array. The memory array may comprise: a gate stack structure; periodically and alternately arranged gate stack regions and channel region spaces; gate dielectric layers for discrete charge storage; periodically arranged channel regions; source doping regions and drain doping regions symmetrically arranged to each other; bit lines led from the source doping regions and the drain doping regions; and word lines led from the gate stack regions. The gate dielectric layers for discrete charge storage can provide physical storage spots to achieve single-bit or multi-bit operations, so as to achieve a high storage density. According to the present disclosure, the localized charge storage characteristic of the charge trapping layer and characteristics such as a longer effective channel length and a higher density of a vertical memory structure are utilized, to provide multiple storage spots in a single memory cell. Therefore, the storage density is improved while good performances such as high speed are ensured.

RADIO FREQUENCY CIRCUIT

A radio frequency (RF) circuit includes a first microchip for transmitting RF signal, a second microchip, two resistors and at least two signal lines. Each signal line has opposite first and second ends, and each first end of each signal line is connected to the first microchip and each second end of each signal line is connected to the second microchip. Each signal line defines first and second gaps, the first gaps are adjacent to the first microchip and the second gaps are adjacent to the second microchip. The two resistors are selectively located at the gaps of any one signal line, whereby the first microchip and the second microchip are connected to each other through the signal line and the resistors to form a connection path. 1. A radio frequency (RF) circuit comprising:a first microchip for receiving and transmitting RF signal;a second microchip for receiving and transmitting RF signal;two resistors; andat least two signal lines, wherein each signal line has opposite first and second ends and each first end of each signal line is electrically connected to the first microchip and each second end of each signal line is electrically connected to the second microchip, each signal line defines first and second gaps, the first gaps adjacent to the first microchip and the second gaps adjacent to the second microchip, and the two resistors are selectively located at the first and second gaps of any one signal line, whereby the first microchip and the second microchip are electrically connected to each other through the signal line and the resistors to form a connection path.2. The RF circuit as claimed in claim 1 , wherein:the first microchip comprises a first signal transmission terminal and a second signal transmission terminal;the second microchip comprises a first communication port and a second communication port; andwhen the RF signals are transmitted from the first signal transmission terminal of the first microchip to the first communication port of the ...

ULTRASOUND CONTRAST AGENTS AND METHODS OF MAKING AND USING THEM

The invention is directed to injectable suspensions of gas-filled microvesicles, as well as methods of preparing and using the same, especially as ultrasound contrast agents. 153.-. (canceled)54. An ultrasound contrast agent comprising an aqueous suspension of gas filled microbubbles comprising a saturated phospholipid , a fatty acid , a hydrophilic stabilizer , and SF , wherein the amount of the saturated phospholipid in the suspension is less than about 0.01% by weight.55. The ultrasound contrast agent of claim 54 , wherein the fatty acid is present in an amount between 1% and 50% by weight of the amount of the saturated phospholipid.56. The ultrasound contrast agent of claim 54 , wherein the fatty acid is present in an amount between 10% and 15% by weight of the amount of the saturated phospholipid.57. The ultrasound contrast agent of claim 54 , wherein the fatty acid is a C-C.straight chain saturated fatty acid selected from the group consisting of lauric acid claim 54 , myristic acid claim 54 , palmitic acid claim 54 , stearic acid claim 54 , arachidic acid claim 54 , behenic acid claim 54 , lignoceric acid and mixtures thereof.58. The ultrasound contrast agent of claim 54 , wherein the fatty acid comprises palmitic acid in an amount between 10% and 15% by weight of the amount of the saturated phospholipid.59. The ultrasound contrast agent of claim 54 , wherein the saturated phospholipid is selected from the group consisting of dimyristoylphosphatidic acid claim 54 , dimyristoylphosphatidylglycerol claim 54 , dimyristoylphosphatidylserine claim 54 , dipalmitoylphosphatidic acid claim 54 , dipalmitoylphosphatidylglycerol claim 54 , dipalmitoylphosphatidylserine claim 54 , distearoylphosphatidic acid claim 54 , distearoylphosphatidylglycerol claim 54 , distearoylphosphatidylserine and mixtures thereof.60. The ultrasound contrast agent of claim 54 , wherein the saturated phospholipid comprises distearoylphosphatidylcholine (DSPC) and ...

HISTONE ACETYLTRANSFERASE ACTIVATORS AND USES THEREOF

The invention provides for a method for screening compounds that bind to and modulate a histone acetyltransferase protein. The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a HAT-activating compound to a subject. 8. A method for screening compounds of Formula (I) , Formula (II) , Formula (III) , or Formula (V) to treat conditions associated with accumulated amyloid-beta peptide deposits , the method comprising:a) administering a HAT Activator compound of Formula (I), Formula (II), Formula (III), or Formula (V) to an animal model of amyloid-beta peptide deposit accumulation; andb) selecting a HAT Activator compound of Formula (I), Formula (II), Formula (III), or Formula (V) that can modulate histone acetylation after administration of the HAT Activator compound in an animal model of amyloid-beta peptide deposit accumulation.9. A method for identifying a histone acetyltransferase (HAT) activator compound of Formula (I) , Formula (II) , Formula (III) , or Formula (V) to treat conditions associated with accumulated amyloid-beta peptide deposits , wherein the method comprises selecting a HAT Activator compound of Formula (I) , Formula (II) , Formula (III) , or Formula (V) having one or more of the following features:{'sub': '50', 'a) the ECof the compound is no more than about 1000 nM;'}b) the histone acetylation activity in vitro targets histone protein H2, H3, and/or H4; andc) the compound penetrates the blood brain barrier; or a combination thereof.10. The method of claim 9 , wherein the compound has a molecular mass less than about 500 Da claim 9 , has a polar surface area less than about 90 Å claim 9 , has less than 8 hydrogen bonds claim 9 , or a combination thereof claim 9 , in order to penetrate the blood brain barrier.12. The method of claim 11 , wherein the subject ...

POWER AMPLIFYING CIRCUIT AND WIRELESS COMMUNICATION DEVICE

A power amplifier circuit includes a first receiving switch, a first sending switch, and a power amplifier. The first receiving switch includes a first receiving switch terminal, a second receiving switch terminal, and a first receiving common terminal selectively connected to the first receiving switch terminal and the second receiving switch terminal The first sending switch includes a first sending switch terminal, a second sending switch terminal, and a first sending common terminal selectively connected to the first sending switch terminal and the second sending switch terminal. The power amplifier includes a first frequency band signal receiving terminal electrically connected to the first receiving common terminal, and a first frequency band signal sending terminal electrically connected to the first sending common terminal. 1. A power amplifying circuit , comprising: a first receiving switch terminal;', 'a second receiving switch terminal; and', 'a first receiving common terminal selectively connected to the first receiving switch terminal and the second receiving switch terminal;, 'a first receiving switch, the first receiving switch comprising a first sending switch terminal;', 'a second sending switch terminal; and', 'a first sending common terminal selectively connected to the first sending switch terminal and the second sending switch terminal; and, 'a first sending switch; the first sending switch comprising a first frequency band signal receiving terminal electrically connected to the first receiving common terminal; and', 'a first frequency band signal sending terminal electrically connected to the first sending common terminal., 'a power amplifier, the power amplifier comprising2. The power amplifying circuit of claim 1 , further comprising a second receiving switch and a second sending switch claim 1 , wherein the second receiving switch comprises a third receiving switch terminal claim 1 , a fourth receiving switch terminal claim 1 , and a second ...

INDUCTANCE MEASURING DEVICE AND METHOD FOR MEASURING AN INDUCTANCE PARAMETER OF PERMANENT MOTOR

The present disclosure provides an inductance parameter measuring device of the permanent motor and the method thereof. The method includes: providing a d-axis given current signal and a q-axis given current signal; converting the d-axis given current signal and the q-axis given current signal to a three-phase command signal and outputting a motor control signal corresponding to the three-phase command signal, and obtaining a three-phase feedback signal, from which a d-axis feedback signal and a q-axis feedback signal is generated, based on the motor control signal; calculating a d-axis inductance and a q-axis inductance based on the first, second, third and fourth response signals when the permanent motor is in a stationary state, wherein the first, second, third and fourth response signals are respectively corresponded to the d-axis given current signal, the q-axis given current signal, the d-axis feedback signal and the q-axis feedback signal. 1. An inductance measuring device for measuring an inductance parameter of a permanent motor , the inductance measuring device comprising:a signal conversion unit, for converting a signal corresponding to a d-axis given current signal and a signal corresponding to a q-axis given current signal into a three-phase command signal, and converting a three-phase feedback signal of the permanent motor into a d-axis feedback signal and a q-axis feedback signal;a power conversion unit for receiving the three-phase command signal and outputting a motor control signal corresponding to the three-phase command signal, so as to obtain the three-phase feedback signal based on the motor control signal; anda parameter calculation unit, for receiving a first response signal corresponding to the d-axis given current signal, a second response signal corresponding to the q-axis given current signal, a third response signal corresponding to the d-axis feedback signal and a fourth response signal corresponding to the q-axis feedback signal, and ...

BENZYLBENZENE DERIVATIVES AND METHODS OF USE

Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition. 2. A compound of claim 1 , wherein Y is C-Ccycloalkyl.3. A compound of claim 1 , selected from the group consisting of:(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-(2-(2-methoxyethoxy)ethoxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;(2S,3R,4R,5S,6R)-2-(3-(4-(2-(allyloxy)ethoxy)benzyl)-4-chlorophenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-(2-(prop-2-ynyloxy)ethoxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-(1-(prop-2-ynyloxy)propan-2-yloxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-(2-(cyclopentyloxy)ethoxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-(2-cyclopropoxyethoxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-(2-(2,2,2-trifluoroethoxy)ethoxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2,4-pyran-3,4,5-triol;(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-(2-(2-fluoroethoxy)ethoxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-(2-(2,2-difluoroethoxy)ethoxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-(2-cyclobutoxyethoxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol; and(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-(2-cyclopropoxypropoxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol.5. A pharmaceutical composition comprising a pharmaceutically acceptable carrier and a compound of any of to .6. A ...

Coating composition and coated paper

A coating composition for forming a paper coat includes nano-fibrillated cellulose, pigment, latex, an auxiliary additive, and water. On a dry weight basis, the nano-fibrillated cellulose is in an amount by weight of 0.02 parts to 10 parts in the total composition, the pigment is in an amount by weight of 75 parts to 95 parts in the total composition, the latex is in an amount by weight of 5 parts to 15 parts in the total composition, and the auxiliary additive is in an amount by weight of 0.35 parts to 10 parts in the total composition.

Enzymatic Preparation Method of Inclusion Complexes of Tributyrin

The disclosure relates to an enzymatic preparation method of inclusion complexes of tributyrin, and belongs to the technical field of oil microencapsulation. The disclosure combines enzymatic synthesis of cyclodextrin and inclusion of tributyrin with cyclodextrin, including enzymatic preparation of cyclodextrin with a CGT enzyme. Tributyrin is added in the preparation process; after reaction, Tween is added, and homogenization and spray drying are carried out. The effect of the finally obtained tributyrin powder is much better than that of single inclusion of tributyrin with cyclodextrin. The disclosure is simple in process, low in cost and convenient in operation; reaction processes are free of toxicity and pollution; there are no toxic reagent residues; the inclusion effect is obvious, and better utilization of a nutritional additive tributyrin in actual production is facilitated. 1. A method of enzymatic preparation of inclusion complexes of tributyrin , comprising: preparing starch milk or a maltodextrin solution as a raw material , wherein a mass concentration of the starch milk or maltodextrin solution is 15% to 30%; adding an enzyme into the starch milk or maltodextrin solution for liquefaction reaction and cyclization reaction; and after the cyclization reaction is completed , adding tributyrin and an emulsifier so that tributyrin is included.2. The method according to claim 1 , wherein starch in the starch milk is one or more of corn starch claim 1 , waxy corn starch claim 1 , potato starch claim 1 , rice starch claim 1 , cassava starch and wheat starch claim 1 , and maltodextrin in the maltodextrin solution is maltodextrin from a starch source with a DE value of 5 to 25.3. The method according to claim 1 , further comprising: after the adding tributyrin and the emulsifier claim 1 , mixing emulsification claim 1 , shearing claim 1 , homogenization and spray drying.4. The method according to claim 1 , wherein the enzyme is cyclodextrin glucosyltransferase.5. ...

AUXILIARY BERTHING METHOD AND SYSTEM FOR VESSEL

The present invention provides an auxiliary berthing method and system for a vessel. In the berthing method, by a solar blind ultraviolet imaging method, a position and an attitude of a vessel relative to a shoreline of a port berth during berthing are calculated by at least two solar blind ultraviolet imaging modules according to light signals received by a solar blind ultraviolet light source array arranged in advance on the shore. Further, when more than three solar blind ultraviolet imaging modules are used, in the method and device of the present invention, a normalized correlation algorithm and a data fusion algorithm are used to improve the accuracy of the position and attitude data of the vessel. 1. A method for berthing a vessel , a position relationship between a vessel and a shoreline being determined by a solar blind ultraviolet imaging method , characterized in that the method comprises the steps of: providing at least two solar blind ultraviolet imaging modules on the vessel , receiving , by the solar blind ultraviolet imaging modules , light signals transmitted by a solar blind ultraviolet light source array arranged in advance on the shore , and processing the light signals by a signal processor to obtain a position relationship between the solar blind ultraviolet imaging modules and a related berth , so as to obtain data on a position relationship between the vessel and the shoreline of the related berth.2. The method for berthing a vessel according to claim 1 , further comprising the following steps of:1) receiving, by the solar blind ultraviolet imaging modules, solar blind ultraviolet light signals transmitted by the solar blind ultraviolet light source array arranged in advance on the shore, measuring information about a position relationship between the vessel and the related berth to obtain a respective translation vector relative to the solar blind ultraviolet light source array, and obtaining a distance from the vessel to a target lattice ...

AUXILIARY BERTHING METHOD AND SYSTEM FOR VESSEL

The present invention provides an auxiliary berthing method and system for a vessel. Position information of a vessel relative to a berth is determined by a solar blind ultraviolet imaging method; meanwhile, by a GPS method, an attitude angle of the vessel relative to the berth is determined by at least two GPS receivers. Thus, the vessel can be berthed safely when getting close to the shore at low visibility. Further, in the method and device of the present invention, it can be preferable to integrate coordinate data and angle data received by a solar blind ultraviolet imaging module and GPS signal receiving modules by a normalized correlation algorithm and a data fusion algorithm, so as to improve the positioning accuracy. 1. An auxiliary berthing method for a vessel , comprising providing a solar blind ultraviolet imaging module and a data processing module on a vessel , the solar blind ultraviolet imaging module measuring , according to received optical signals transmitted by a solar blind ultraviolet light source array arranged in advance on the shore , information about a position relationship between the vessel and a related berth , characterized in that the method further comprises the steps of:1) providing at least two GPS signal receiving modules, at least one of which is arranged on the vessel, used for receiving a position signal of the vessel from a related satellite; and2) designing the data processing module to comprise a signal receiving element which can be matched with the solar blind ultraviolet imaging module and the GPS signal receiving module in a wired and/or wireless manner, receiving data related to the position of the vessel from the solar blind ultraviolet imaging module and the GPS signal receiving module, calculating coordinate values of a reference point of the vessel, and determining an attitude angle of the vessel relative to a shoreline of the berth according to the position data from the solar blind ultraviolet imaging module and ...

ACCESS CONTROL IN THE REMOTE DEVICE OF NETWORK REDIRECTOR

An approach for accessing one or more resources at a virtualized desktop infrastructure (VDI) client running on a client device by a remote virtual machine (VM) is provided. The method includes intercepting, via a VDI agent, a request to access one or more resources at the client device, transferring the request from the remote VM to the client device via a network redirector protocol, and filtering the request to determine if the request complies with one or more rules. For a first resource of the one or more resources, if the request does not comply with any one of one or more first rules of the one or more rules, access to the first resource is denied. If the request complies with the one or more first rules, access to the first resource is granted and a response is sent to the VDI agent via the network redirector protocol. 1. A method of accessing one or more resources at a virtualized desktop infrastructure (VDI) client running on a client device by a remote virtual machine (VM) , wherein the remote VM is connected to the VDI client through a network and the remote VM and VDI client provide a virtual desktop at the client device , the method comprising:receiving, by the VDI client of the client device from a VDI agent at the remote VM, a request to access at least one resource associated with the client device, the request generated based on an input at the virtual desktop;determining at the VDI client of the client device whether to grant access to the at least one resource based on one or more rules defined for accessing resources associated with the client device; andwhen the at least one resource is determined to be accessible based on the one or more rules, granting, by the VDI client of the client device, access to the first at least one resource and sending, by the VDI client of the client device, a response to the VDI agent of the remote VM.2. The method of claim 1 , wherein the at least one resource comprises a first resource and a second resource and ...

Methods of Attracting Drosophila Suzukii Using Acetoin Blend

Methods of attracting , involving treating an object or area with a attracting effective amount of a composition containing acetoin and at least one compound selected from ethyl octanoate, acetic acid, ethyl acetate, phenethyl alcohol, or mixtures thereof; wherein said composition does not contain ethanol. 1. (canceled)2. (canceled)3. (canceled)4. (canceled)5. (canceled)6. (canceled)7Drosophila suzukii. A composition for attracting , said composition comprising:{'i': 'Drosophila suzukii', '(a) an effective attracting amount of at least acetoin, and ethyl octanoate, wherein said composition does not contain a repellent compound and'}(b) optionally a carrier.8. The composition of wherein said composition further comprises acetic acid.9. The composition of wherein said composition further comprises ethyl acetate.10. The composition of wherein said composition further comprises phenethyl alcohol.11Drosophila suzukii. The composition of claim 7 , wherein said repellent compound is ethanol.12Drosophila suzukii. The composition of claim 7 , wherein said repellent compound is 2-methyl-1-butanol.13Drosophila suzukii. The composition of claim 7 , wherein said repellent compound is ethanol and 2-methyl-1-butanol.14. An insect trap comprising the attracting composition of .15. An insect trap comprising the attracting composition of .16. An insect trap comprising the attracting composition of .17. An insect trap comprising the attracting composition of .18Drosophila suzukiiDrosophila suzukii. A method of attracting claim 10 , said method comprising treating an object or area with a attracting effective amount of a composition comprising acetoin and ethyl octanoate claim 10 , and at least one compound selected from the group consisting of acetic acid claim 10 , ethyl acetate claim 10 , phenethyl alcohol claim 10 , and mixtures thereof; wherein said composition does not contain ethanol.19. The method according to claim 18 , wherein said composition does not contain 2-methyl-1- ...

METHOD AND DEVICE FOR DETERMINING UNMANNED VEHICLE RUNNING SCENE

Embodiments of the present application provide a method and a device for determining an unmanned vehicle running scene. In the method, firstly, a data collection instruction sent by a server is received; then traveling data corresponding to the type of the data to be collected is acquired when the collection condition is met; and finally, the traveling data is sent to the server, so that the server determines and restores a running scene of the unmanned vehicle. Since the data collection instruction is sent by the server, and the corresponding traveling data is collected according to the collection condition and the type of data to be collected, the traveling data is determined according to the data collection instruction, so that the server can acquire the traveling data of the unmanned vehicle according to the data collection instruction, and accurately analyze the running scene of the unmanned vehicle. 1. A method for determining an unmanned vehicle running scene , wherein the method is applied to an unmanned vehicle , and comprises:receiving a data collection instruction sent by a server, wherein the data collection instruction comprises a collection condition and a type of data to be collected;acquiring traveling data corresponding to the type of the data to be collected when the collection condition is met; andsending the traveling data to the server, so that the server determines and restores a running scene of the unmanned vehicle according to the traveling data.2. The method according to claim 1 , wherein the collection condition comprises at least one of a target time claim 1 , a target obstacle quantity claim 1 , a target location and a target traveling state;the acquiring traveling data corresponding to the type of the data to be collected when the collection condition is met comprises:acquiring target data sent by a sensing device of the unmanned vehicle in real time, wherein the target data comprises at least one of a time parameter, an obstacle ...

ADDUCTS AS TOUGHENERS IN THERMOSETTABLE EPOXY SYSTEMS

A liquid adduct consisting essentially of a reaction product of (a) an aliphatic epoxy resin, and (b) an isocyanate compound, wherein the viscosity of the adduct comprises less than about 60 Pa-s at about 25° C. is disclosed. The adduct can be used in an epoxy resin composition. 1. A liquid adduct consisting essentially of a reaction product of(a) an aliphatic epoxy resin, and(b) an isocyanate compound; wherein the viscosity of the adduct comprises less than about 60 Pa-s at about 25° C.2. The adduct of claim 1 , wherein the epoxy resin comprises a polyglycol epoxy resin.3. The adduct of claim 1 , wherein the polyglycol epoxy resin comprises polypropylene glycol claim 1 , polyethylene glycol claim 1 , and mixtures thereof.4. (canceled)5. The adduct of wherein the isocyanate compound is a polyfunctional isocyanate compound.6. (canceled)7. The adduct of including (c) a catalyst.8. The adduct of wherein the weight ratio of (a) to (b) is between 60 to 98 for component (a) and 40 to 2 for component (b).9. The adduct of wherein the isocyanate compound is selected from the group consisting of MDI claim 1 , TDI claim 1 , hydrogenated MDI claim 1 , hydrogenated TDI claim 1 , and combinations thereof.10. The adduct of wherein the polyglycol epoxy resin is selected from the group consisting of poly propyleneglycol diglycidyl ether claim 1 , dipropyleneglycol diglycidyl ether claim 1 , 1 claim 1 ,6-Hexanediol diglycidyl ether claim 1 , 1 claim 1 ,4-Butanediol diglycidyl ether and combinations thereof.12. The adduct of wherein the catalyst is selected from the group consisting of 2-methyl imidazole claim 7 , 2-phenyl imidazole claim 7 , an imidazole derivative claim 7 , 1 claim 7 ,8-diazabicyclo[5.4.0]undec-7-ene (DBU) claim 7 , 2-methylimidazole-epoxy adduct claim 7 , an isocyanate-amine adduct claim 7 , and combinations thereof.13. A composition comprising (a) the adduct of ; (b) at least one epoxy resin; and (c) at least one hardener.14. The composition according to claim 13 ...

VEHICLE MAINTENANCE METHOD USING MOBILE VEHICLE MAINTENANCE STATION

A vehicle maintenance method using a mobile vehicle maintenance station, includes: determining a location of a vehicle to be maintained; and a technician taking the maintenance station to the location of the vehicle to be maintained and using the maintenance station to perform corresponding maintenance operations on the vehicle to be maintained. The maintenance operations include: taking a lifting mechanism out of a compartment of the maintenance station, and supporting the lifting mechanism on the ground; moving the vehicle to be maintained to the lifting mechanism and fixing the same thereto; and raising the vehicle to be maintained to a predetermined height by using the lifting mechanism so that an overhead space is formed between a chassis of the vehicle to be maintained and the ground, and the technician entering the overhead space to perform maintenance operations on the chassis of the vehicle to be maintained. 1. A vehicle maintenance method using a mobile vehicle maintenance station , comprising the following steps of:determining a location of a vehicle to be maintained;carrying the mobile vehicle maintenance station to the location of the vehicle to be maintained and using the mobile vehicle maintenance station to perform corresponding maintenance operations on the vehicle to be maintained;wherein during the maintenance operations the vehicle to be maintained is raised by using a lifting mechanism of the mobile vehicle maintenance station and the corresponding maintenance operations are performed, and the maintenance operations include the following steps of:taking the lifting mechanism out of a compartment of the mobile vehicle maintenance station and supporting the lifting mechanism on the ground;moving the vehicle to be maintained on the lifting mechanism and fixing the same thereto; andraising the vehicle to be maintained to a predetermined height by using the lifting mechanism so that an overhead space for the maintenance operations is formed between a ...

OXAZOLIDONE RING CONTAINING VINYL ESTER RESIN AND PRODUCTS THEREFROM

A process comprising contacting a) an epoxy resin; b) an adduct comprising at least one oxazolidone ring prepared from a multifunctional epoxy resin and an isocyanate compound; and c) an unsaturated acid to form a vinyl ester, is disclosed. 1. A process comprising:contactinga) an epoxy resin;b) an adduct comprising at least one oxazolidone ring prepared from a multifunctional epoxy resin having a functionality of more than 2.1 and an EEW of from 100 to 300 and an isocyanate compound; andc) an unsaturated acidto form a vinyl ester.2. The process of claim 1 , wherein the epoxy resin is selected from the group consisting of phenol novolac epoxy resins claim 1 , cresol novolac epoxy resins claim 1 , novolac epoxy resins claim 1 , tris-epoxy resins claim 1 , epoxidized tetrafunctional phenol ethane claim 1 , epoxidized cyclohexane tetraphenol claim 1 , dicyclopentadiene epoxy resins claim 1 , and mixtures thereof.3. The process of wherein the multifunctional epoxy resin is selected from the group consisting of phenol novolac epoxy resins claim 1 , cresol-novolac epoxy resins claim 1 , bisphenol-A novolac epoxy resins claim 1 , epoxidized tetrafunctional phenol ethane claim 1 , epoxidized cyclohexane tetraphenol claim 1 , trisepoxy resins claim 1 , polyfunctional epoxy resins claim 1 , naphthalene epoxy resins claim 1 , divinylbenzene claim 1 , dicyclopentadiene-type epoxy resins claim 1 , phosphorous containing epoxy resins claim 1 , multi aromatic epoxy resins claim 1 , and mixtures thereof.4. The process of wherein the isocyanate compound has an isocyanate group of 2 or more and an IEW of from 100 to 500.5. The process of wherein the isocyanate compound is a polymeric isocyanate compound.6. The process of claim 1 , wherein the unsaturated acid is selected from the group consisting of acrylic acid claim 1 , methacrylic acid claim 1 , cinnamic acid claim 1 , crotonic acid claim 1 , sorbic acid claim 1 , monomethyl maleate claim 1 , monobutyl maleate claim 1 , half esters ...

A POLYISOCYANATE COMPONENT, A POLYURETHANE FOAMING SYSTEM AND AN ARTICLE MADE THEREFROM

A polyisocyanate component, a polyurethane foaming system, and an article made therefrom, wherein the polyisocyanate component includes (a) a preformed mixture including an aromatic oxazolidone compound that is the reaction product of at least one aromatic epoxide and at least one first polyisocyanate having an average isocyanate functionality of no more than 2.7 and greater than 1.8, in the presence of at least one catalyst, the aromatic oxazolidone compound includes at least one free isocyanate group and at least one aromatic oxazolidone group, the aromatic oxazolidone group includes an aromatic group and an oxazolidone group, and (b) at least one second polyisocyanate has an average isocyanate functionality equal to or greater than 2.7 and less than 6.0. The second polyisocyanate is added to the preformed mixture to form the polyisocyanate component. The polyisocyanate component has a viscosity of no more than 4.0 Pa-sat 25° C., an aromatic oxazolidone group content of 2 weight percent to 10 weight percent based on a total weight of the polyisocyanate component, and an average isocyanate functionality of from 1.8 to 6.0. 1. A polyisocyanate component , comprising a preformed mixture including (a) an aromatic oxazolidone compound that is the reaction product of(i) at least one epoxide compound having at least one aromatic group and(ii) at least one first polyisocyanate compound having an average isocyanate functionality of no more than 2.7 and greater than 1.8, in the presence of(iii) at least one catalyst, wherein the aromatic oxazolidone compound includes at least one free isocyanate group and at least one aromatic oxazolidone group, and wherein the aromatic oxazolidone group includes an aromatic group and an oxazolidone group; andwherein the polyisocyanate component has a viscosity of no more than 4.0 Pa-s at 25° C., wherein the content of the aromatic oxazolidone group in the polyisocyanate component is from 2 weight percent to 10 weight percent based on a ...

AZETIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF

The present invention relates to an azetidine derivative for use as a Janus kinase (JAK) inhibitor, a drug composition comprising same, a preparation method therefor, and a use thereof in the treatment of JAK-related diseases comprising, for example, inflammatory diseases, autoimmune diseases, and cancers. 14. The method according to claim 8 , wherein the JAK-related disease is selected from the group consisting of an inflammatory disease claim 8 , autoimmune disease claim 8 , and cancer.15. The method according to claim 8 , wherein the JAK-related disease is selected from the group consisting of an inflammatory bowel disease claim 8 , lupus claim 8 , and psoriasis.16. The method according to claim 13 , wherein the JAK-related disease is selected from the group consisting of an inflammatory disease claim 13 , autoimmune disease claim 13 , and cancer.17. The method according to claim 13 , wherein the JAK-related disease is selected from the group consisting of an inflammatory bowel disease claim 13 , lupus claim 13 , and psoriasis.18. The method according to claim 8 , wherein the therapeutically effective amount is selected from the group consisting of about 0.01 mg to about 1000 mg claim 8 , 0.1-500 mg claim 8 , 0.5-300 mg claim 8 , 1-150 mg claim 8 , 1-50 mg claim 8 , or 25 mg.19. The method according to claim 8 , wherein the therapeutically effective amount is selected from the group consisting of 0.5 mg claim 8 , 1 mg claim 8 , 1.5 mg claim 8 , 2 mg claim 8 , 3 mg claim 8 , 4 mg claim 8 , 6 mg claim 8 , 8 mg claim 8 , or 10 mg.20. The method according to claim 8 , wherein the therapeutically effective amount is selected from the group consisting of 0.5 mg claim 8 , 1 mg claim 8 , 1.5 mg claim 8 , 2 mg claim 8 , 3 mg claim 8 , 4 mg claim 8 , or 6 mg.21. The method according to claim 13 , wherein the therapeutically effective amount is selected from the group consisting of about 0.01 mg to about 1000 mg claim 13 , 0.1-500 mg claim 13 , 0.5-300 mg claim 13 , 1-150 ...

WATERBORNE POLYURETHANE DISPERSION AND METHOD FOR PREPARING THE SAME

Provided is a waterborne polyurethane dispersion. The waterborne polyurethane dispersion is prepared in the presence of a hydrophilic amino siloxane compound and exhibits good anti-stickiness while retaining superior mechanical properties. A laminated synthetic leather article prepared with said waterborne polyurethane dispersion as well the method for preparing the synthetic leather article are also provided. 2. The waterborne polyurethane dispersion according to claim 1 , wherein there is no cationic or anionic hydrophilic pendant groups or groups which can be converted into the cationic or anionic hydrophilic pendant groups covalently attached to the backbone chain of polyurethane in the polyurethane particles claim 1 , and the polyurethane is externally emulsified.3. The waterborne polyurethane dispersion according to claim 1 , wherein the one or more compounds having at least two isocyanate groups are selected from the group consisting of:a) C4-C12 aliphatic polyisocyanates comprising at least two isocyanate groups, C6-C15 cycloaliphatic or aromatic polyisocyanates comprising at least two isocyanate groups, C7-C15 araliphatic polyisocyanates comprising at least two isocyanate groups, and a combination thereof; andb) an isocyanate prepolymer prepared by reacting one or more polyisocyanates of a) with one or more isocyanate-reactive components selected from the group consisting of C2-C16 aliphatic polyhydric alcohols comprising at least two hydroxy groups, C6-C15 cycloaliphatic or aromatic polyhydric alcohols comprising at least two hydroxy groups, C7-C15 araliphatic polyhydric alcohols comprising at least two hydroxy groups, polyester polyols having a molecular weight from 500 to 5,000, polycarbonate diols having a molecular weight from 200 to 5,000, polyetherdiols having a molecular weight from 200 to 5,000, C2 to C10 polyamine comprising at least two amino groups, C2 to C10 polythiol comprising at least two thiol groups, C2-C10 alkanolamine comprising at least ...

MULTIPLE POOLS IN A MULTI-CORE SYSTEM

A system in accordance with an example includes a cluster and a scheduler engine coupled to the cluster. The cluster includes a plurality of nodes, wherein each node includes a faster core and a slower core and the plurality of nodes thereby includes a plurality of faster cores and a plurality of slower cores. The scheduler engine is to create a virtual fast pool and a virtual slow pool. The virtual fast pool includes the faster cores from the nodes and the virtual slow pool includes the slower cores from the nodes. Each faster core in the virtual fast pool is to process a job from a first job queue, and each slower core in the virtual slow pool is to process a job from a second job queue. 1. A system , comprising:a cluster comprising a plurality of nodes, wherein each node comprises a faster core and a slower core, the plurality of nodes thereby including a plurality of faster cores and a plurality of slower cores; anda scheduler engine coupled to the cluster, the scheduler engine is to create a virtual fast pool including the faster cores from the nodes and a virtual slow pool including the slower cores from the nodes;wherein each faster core in the virtual fast pool is to process a job from a first job queue, and each slower core in the virtual slow pool is to process a job from a second job queue.2. The system of claim 1 , wherein the scheduler engine is further to create a virtual shared pool including at least one of a faster core and a slower core from the respective virtual fast and slow pools claim 1 , wherein a slower core in the virtual shared pool is to process a first job from the first job queue based on an unavailability of a faster core in the virtual fast pool claim 1 , and a faster core in the virtual shared pool is to process a second job from the second job queue based on an unavailability of a slower core from the virtual slow pool.3. The system of wherein each node includes a task tracker to:monitor an availability of the faster and slower ...

METHODS OF TREATMENTS USING CTLA-4 ANTIBODIES

In certain embodiments, the present invention, the present invention provides a method of treating a cancer in a subject, comprising: (a) administering to the subject a predetermined dosage of an anti-CTLA4 antibody; (b) detecting the level of the anti-CTLA4 antibody in a sample of the subject; and (c) increasing the dosage of the anti-CTLA4 antibody in the subject if the level of the anti-CTLA4 antibody from step (b) is below a threshold exposure level, such that the cancer is treated. 1. A method of treating a cancer in a subject in need of treatment , comprising:(a) administering to the subject a predetermined dosage of an anti-CTLA4 antibody;(b) detecting the level of the anti-CTLA4 antibody in a sample of the subject; and(c) increasing the dosage of the anti-CTLA4 antibody in the subject if the level of the anti-CTLA4 antibody from step (b) is below a threshold exposure level, such that the cancer is treated in the subject.2. The method of claim 1 , wherein the anti-CTLA4 antibody is a human antibody.3. The method of claim 2 , wherein the anti-CTLA4 antibody is MDX-010.4. The method of claim 1 , wherein the anti-CTLA4 antibody comprises:(a) a heavy chain variable region comprising the amino acid sequence of SEQ ID NO: 1; and(b) a light chain variable region comprising the amino acid sequence of SEQ ID NO: 2.5. The method of claim 4 , wherein the anti-CTLA4 antibody comprises:(a) a heavy chain variable region CDR1 comprising SEQ ID NO: 3;(b) a heavy chain variable region CDR2 comprising SEQ ID NO: 4;(c) a heavy chain variable region CDR3 comprising SEQ ID NO: 5;(d) a light chain variable region CDR1 comprising SEQ ID NO: 6;(e) a light chain variable region CDR2 comprising SEQ ID NO: 7; and(f) a light chain variable region CDR3 comprising SEQ ID NO: 8.6. The method of claim 1 , wherein the level of the anti-CTLA4 antibody is detected by an immunoassay in step (b).7. The method of claim 6 , wherein the immunoassay comprises contacting said sample with an antigen ...

PHOSPHODIESTERASE INHIBITORS AND USES THEREOF

The invention provides for compounds that are phosphodiesterase inhibitors. The invention further provides for a method for screening compounds that bind to and modulate a phosphosdiesterase protein. The invention also provides methods for treating conditions associated with accumulated amyloid-beta peptide deposit accumulations by administering a phosphodiesterase-binding compound to a subject. 143-. (canceled)45. The method of claim 44 , wherein the effective amount is at least about 1 mg/kg body weight claim 44 , at least about 2 mg/kg body weight claim 44 , at least about 3 mg/kg body weight claim 44 , at least about 4 mg/kg body weight claim 44 , at least about 5 mg/kg body weight claim 44 , at least about 6 mg/kg body weight claim 44 , at least about 7 mg/kg body weight claim 44 , at least about 8 mg/kg body weight claim 44 , at least about 9 mg/kg body weight claim 44 , or at least about 10 mg/kg body weight.46. The method of claim 44 , wherein A is N.47. The method of claim 44 , wherein Ris hydrogen.48. The method of claim 44 , wherein Ris —OCH.50. The method of claim 48 , wherein Ris CH.52. The method of claim 44 , wherein Ris CH—OH.53. The method of claim 44 , wherein Ris H.54. The method of claim 44 , wherein Ris a halogen.55. The method of claim 44 , wherein Ris chlorine.56. The method of claim 44 , wherein Ris —CN.57. The method of claim 44 , wherein Ris a halogen.58. The method of claim 44 , wherein Ris fluorine.60. The method of claim 44 , wherein Ris hydrogen.61. The method of claim 44 , wherein Ris C-Ccycloalkyl claim 44 , —NRR claim 44 , or —SR.62. The method of claim 44 , wherein Ris C-Ccycloalkyl or —NRR.63. The method of claim 44 , wherein Ris —NRR.64. The method of claim 44 , wherein Ris —NRR claim 44 , and wherein Rand Rare each independently hydrogen claim 44 , —C-Calkyl claim 44 , —C-Ccycloalkyl claim 44 , or —C(O)R claim 44 , wherein the C-Calkyl or C-Ccycloalkyl are optionally substituted with —C-Calkyl claim 44 , —C-Ccycloalkyl claim 44 , ...

OXAZOLIDONE RING CONTAINING VINYL ESTER RESIN AND PRODUCTS THEREFROM

A process comprising contacting a) an epoxy resin; b) an adduct comprising at least one oxazolidone ring prepared from a multifunctional epoxy resin and an isocyanate compound; and c) an unsaturated acid to form a vinyl ester, is disclosed. 1. A process comprising:contactinga) an epoxy resin wherein the epoxy resin is selected from the group consisting of phenol novolac epoxy resins, cresol novolac epoxy resins, bis-phenol A novolac epoxy resins, bisphenol-A novolac epoxy resins, tris-epoxy resins, epoxidized tetrafunctional phenol ethane, epoxidized cyclohexane tetraphenol, dicyclopentadiene epoxy resins, and mixtures thereof;b) an adduct comprising at least one oxazolidone ring prepared from a multifunctional epoxy resin and an isocyanate compound; andc) an unsaturated acidto form a vinyl ester.2. (canceled)3. The process of wherein the multifunctional epoxy resin is selected from the group consisting of phenol novolac epoxy resins claim 1 , cresol-novolac epoxy resins claim 1 , bisphenol-A novolac epoxy resins claim 1 , epoxidized tetrafunctional phenol ethane claim 1 , epoxidized cyclohexane tetraphenol claim 1 , trisepoxy resins claim 1 , polyfunctional epoxy resins claim 1 , naphthalene epoxy resins claim 1 , divinylbenzene claim 1 , dicyclopentadiene-type epoxy resins claim 1 , phosphorous containing epoxy resins claim 1 , multi aromatic epoxy resins claim 1 , and mixtures thereof.4. The process of claim 1 , wherein the multifunctional epoxy resin comprises an epoxy resin having a functionality of at more than 2.1 and an EEW of from 100 to 300.5. The process of wherein the isocyanate compound has an isocyanate group of 2 or more and an IEW of from 100 to 500.6. The process of wherein the isocyanate compound is a polymeric isocyanate compound.7. The process of claim 1 , wherein the unsaturated acid is selected from the group consisting of acrylic acid claim 1 , methacrylic acid claim 1 , cinnamic acid claim 1 , crotonic acid claim 1 , sorbic acid claim 1 , ...

Highly sensitive biomarker biosensors based on organic electrochemical transistors

The present technology for the detection and analysis of analytes within a sample is based on molecular biology methods, including western blotting, gel electrophoresis, mass spectrometry, enzyme-linked immunosorbent assays and RT-PCR, which are normally time-consuming and laborious. The present disclosure provides novel OECT based electrochemical biosensors that can enable the convenient and cost-effective determination of analytes within a sample with high sensitivity and selectivity. 2. The electrochemical biosensor according to claim 1 , wherein the first agent and/or the second agent is an antibody.3. The electrochemical biosensor according to claim 1 , wherein the first agent is a monoclonal antibody capable of specifically binding to the analyte.4. The electrochemical biosensor according to claim 1 , wherein the first agent is a nucleic acid probe capable of specifically binding to the analyte.5. The electrochemical biosensor according to claim 1 , wherein the second agent is a polyclonal antibody capable of specifically binding to the analyte.6. The electrochemical biosensor according to claim 1 , wherein the electrochemically active enzyme is horseradish peroxidase and the substrate for the electrochemically active enzyme is hydrogen peroxide.7. The electrochemical biosensor according to claim 1 , wherein the organic semiconductor comprises a film coating on the drain and source electrodes.8. The electrochemical biosensor according to claim 1 , wherein the organic semiconductor comprises poly (3 claim 1 ,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS).9. The electrochemical biosensor according to claim 1 , wherein at least one of the plurality of electrodes and/or the plurality of nanoparticles further comprises gold.10. The electrochemical biosensor according to claim 1 , wherein the gate electrode comprises grooves comprising the first agent capable of specifically binding to an analyte.11. The electrochemical biosensor according to claim 1 , ...

ZERO-DISCHARGE TECHNIQUE FOR SEPARATING SLUDGE AND SALT FROM DESULFURIZATION WASTEWATER

A zero discharge process for separating sludge and salt from desulfurization wastewater includes a pretreatment process, a membrane treatment process and an evaporative crystallization process; in the pretreatment process, the desulfurization wastewater enters a raw water tank, an aeration fan introduces compressed air into the raw water tank, and the wastewater is lifted to first-stage reaction and clarification by a raw water pump; in the membrane treatment process, the incoming wastewater is first filtered by ultrafiltration, then enters a pH adjustment tank, and is pumped into a nanofiltration membrane separation system and a reverse osmosis membrane separation system; in the evaporative crystallization process, the incoming wastewater is first subjected to two-stage preheating, then enters a degasser, and finally enters an evaporative concentration system and a crystallization system. 1. A zero discharge process for separating sludge and salt from desulfurization wastewater , characterized by sequentially including a pretreatment process , a membrane treatment process and an evaporative crystallization process:the pretreatment process:(1) the desulfurization wastewater enters a raw water tank, an aeration fan introduces compressed air into the raw water tank, and the wastewater is lifted to first-stage reaction and clarification by a raw water pump;{'sub': 2', '3, '(2) in the first-stage reaction and clarification, lime milk is added to a first-stage reaction tank, the pH value is adjusted to 8-9 under stirring conditions, iron, zinc, lead, nickel and chromium are produced into hydroxide precipitate, fluoride ions are produced into CaFprecipitate, and silicon is produced into CaSiOprecipitate; an appropriate amount of organic sulfur is added to make mercury and copper produce sulfide precipitate, and an appropriate amount of coagulant and coagulant aid are added to form easily separated large particle precipitate; the wastewater overflows into a first-stage ...

KDR AND VEGF/KDR BINDING PEPTIDES AND THEIR USE IN DIAGNOSIS AND THERAPY

The present invention provides polypeptides, peptide dimers, and multimeric complexes comprising at least one binding moiety for KDR or VEGF/KDR complex, which have a variety of uses wherever treating, detecting, isolating or localizing angiogenesis is advantageous. Particularly disclosed are synthetic, isolated polypeptides capable of binding KDR or VEGF/KDR complex with high affinity (e.g., having a K<1 μM), and dimer and multimeric constructs comprising these polypeptides, particularly contrast agents. Also provided are methods for monitoring and evaluating the therapeutic effectiveness of treatment protocols for diseases associated with angiogenesis or endothelial cell hyperproliferation, such as cancer, using contrast agents of the invention. 112-. (canceled)13. A method for adjusting a treatment protocol comprising:(a) administering an ultrasound contrast agent comprising a KDR binding peptide to a subject with a disorder associated with cell hyperproliferation or angiogenesis;(b) obtaining an initial image of the subject;(c) administering a therapeutic agent appropriate for the treatment of the disorder;(d) obtaining a subsequent image of the subject;(e) comparing the initial and the subsequent images to evaluate the effectiveness of the therapy;(f) determining whether the effectiveness of the therapy is adequate; and(g) if the effectiveness of the therapy is determined not to be adequate, adjusting said treatment protocol, terminating said treatment protocol or administering a different treatment protocol.14. The method of claim 13 , wherein the disorder is cancer.16. The method of claim 13 , wherein the ultrasound contrast agent comprises one or more KDR binding dimers selected from the group consisting of: D5 claim 13 , D6 claim 13 , and D23.17. The method of claim 13 , wherein the ultrasound contrast agent comprises a dimer.18. The method of claim 16 , wherein the dimer is D5.19. The method of claim 13 , wherein the initial and subsequent images are ...

Automatic Liquid Injection System and Method

A power assisted method and injector device for controllably delivering to patients a dispersion medicament or diagnostically active agent, the homogeneity of which is preserved throughout delivery. Diagnostically active agents disclosed are gas microbubble suspensions useful in ultrasonic diagnostic imaging and liposomal formulations in which liposome vesicles are loaded with iodinated compounds. 1. A method of administering to patients by injection or infusion a suspension of microparticles homogeneously distributed in an aqueous liquid carrier by means of an injector system comprising a syringe containing said suspension and a power driven piston for injecting said suspension into a patient , characterised by subjecting the syringe containing the suspension to a rotation or rocking motion , thereby maintaining said suspension homogeneous by preventing segregation of the microparticles by gravity or buoyancy , this being without damaging said microparticles or disturbing their distribution.2. The method of claim 1 , in which said rotation or rocking motion is provided by means under motion for supporting the syringe.3. The method of claim 1 , in which said motion of rocking or rotation is alternated.4. The method of claim 1 , in which said motion is applied along or around the syringe longitudinal axis.5. The method of claim 3 , in which said motion is further applied along or around the syringe transverse axis.6. The method of claim 4 , in which said motion is provided by subjecting the syringe to continuous or intermittent rotation.7. The method of claim 5 , in which said motion is provided by subjecting the syringe to continuous or intermittent rotation.8. The method of claim 4 , in which the rotation rate is from 0.5 to 200 rpm.9. The method of claim 5 , in which the rotation rate is from 0.5 to 200 rpm.10. The method of claim 4 , in which said motion is alternating rotation the direction of which is reversed every 30° claim 4 , 60° claim 4 , 90° claim 4 , 180 ...

Tool for Investigating the Performance of a Distributed Processing System

A performance investigation tool (PIT) is described herein for investigating the performance of a distributed processing system (DPS). The PIT operates by first receiving input information that describes a graph processing task to be executed using a plurality of computing units. The PIT then determines, based on the input information, at least one time-based performance measure that describes the performance of a DPS that is capable of performing the graphical task. More specifically, the PIT can operate in a manual mode to explore the behavior of a specified DPS, or in an automatic mode to find an optimal DPS from within a search space of candidate DPSs. A configuration system may then be used to construct a selected DPS, using the plurality of computing units. In one case, the graph processing task involves training a deep neural network model having a plurality of layers. 1. A method for investigating a performance of a distributed processing system and then building the distributed processing system , comprising:receiving, via a computer-implemented performance investigation tool (PIT), input information that describes at least some characteristics of a graph processing task to be executed in a distributed manner using a plurality of computing units;determining, based on the input information, and using the computer-implemented PIT, at least one time-based performance measure that describes a prospective performance of a distributed processing system that is capable of performing the graph processing task using the plurality of computing units; andconstructing the distributed processing system using the plurality of computing units.2. The method of claim 1 , wherein the graph processing task comprises training a deep neural network model having a plurality of layers.3. The method of claim 1 , wherein claim 1 , in a manual mode of operation:the input information describes a particular candidate distributed processing system under consideration, andsaid ...

Medical Trolley Cart

A medical trolley cart having a main housing with an interior chamber. The main housing has front, back, first side, second side, top and bottom panels. A front door on the front of said main housing provides accessing an interior chamber, which may have a plurality of sliding shelves. A rear door on the rear of said main housing provides access to a rear portion of the interior chamber or to a second chamber within the cart. The rear door has a hinge around which the door is opened and a latch for holding the rear door in a closed position. The rear door opens to a maximum point at which the rear door forms an angle of 15-40 degrees with the main housing. 1. A medical trolley cart comprising:a main housing having an interior chamber, said housing having a front, back, first side, second side, top and bottom, said top of said housing being angled from front to back by 10-30 degrees;a front door on the front of said main housing for accessing said interior chamber; anda rear door on the rear of said main housing for accessing a rear portion of said interior chamber, said rear door having a hinge around which the door is opened, a latch for holding the rear door in a closed position, and a stop means for limiting said rear door to opening to a maximum point at which the rear door forms an angle of 15-40 degrees with the main housing.2. A medical trolley cart according to wherein said rear door opens to a maximum angle of 30 degrees.4. A medical trolley according to further comprising a cable winder connected to said bottom of said main housing.5. A medical trolley according to claim 1 , further comprising a plurality of locking wheels connecting to the bottom of said main housing.6. A medical trolley cart according to further comprising a vertical post connected to said main housing.7. A medical trolley cart according to claim 6 , further comprising:a slidable connecting hinge mounted on said vertical post; anda support arm connected to said slidable connecting hinge. ...

Robotic Surgical System

A robotic surgical system and accessory having a robotic base or hand piece having a plurality of motors and a mechanical actuator each for operating a mechanical positioning arm in a different degrees of freedom. The robotic base is reusable and provides the platform for the system. The drive system has a port that interfaces with the robotic base and allows for insertion of surgical instruments into the base. 1. A robotic surgical system comprising: a rigid housing having a body portion and a grip portion, said body portion having a nosepiece;', a frame;', 'a plurality of motors secured to said frame, each motor having a drive shaft;', 'a drive spool connected to the drive shaft of each motor;', 'a friction drive having a spool connected to a drive spool by a drive band;', 'a friction drive ring driven by said friction drive;', 'a plurality of drive rods supported by said frame;', 'a secondary spool connected to each of said plurality of drive rods;', 'a drive band connecting each secondary spool to a drive spool;', 'a plurality of drive rings, each drive ring being driven by one of said plurality of drive rods; and', 'control electronics electrically connected to said drive motors;, 'a motor assembly within said rigid housing, said motor assembly comprising, 'a control mechanism connected to said control electronics and extending through an opening in said rigid housing;', 'a mode control mechanism connected to said control electronics and extending through an opening in said rigid housing; and', 'a connector for connecting a power source for providing power to said control electronics and said motors; and, 'a hand piece comprisinga mechanical arm connected to said hand piece, said mechanical arm having a plurality of degrees of freedom with each of said plurality of degrees of freedom being controlled by one of said plurality of motors.2. A robotic surgical system according to claim 1 , wherein said hand piece further comprises a mechanical trigger for ...

METHODS, APPARATUSES, ELECTRONIC DEVICE AND MEDIUM FOR ACQUIRING MAP DATA

The present disclosure discloses a method, an apparatus, an electronic device and a medium for acquiring map data, and relates to the field of intelligent transportation. A specific implementation solution is: determining a target areas of interest in a map, wherein the map is divided into at least two areas of interest; sending a data acquisition instruction to data acquisition terminals to acquire the map data in the target areas of interest; and receiving the map data fed back from the data acquisition terminal and updating the target areas of interest in the map according to the map data. 1. A method for acquiring map data , comprising:determining target areas of interest in a map, wherein the map is divided into at least two areas of interest;sending a data acquisition instruction to data acquisition terminals to acquire the map data in the target areas of interest; andreceiving the map data fed back from the data acquisition terminals, and updating the target areas of interest in the map according to the map data.2. The method as claimed in claim 1 , wherein the areas of interest in the map are divided on a basis of a topological structure of roads claim 1 , each area of interest comprising at least one road.3. The method as claimed in claim 1 , wherein determining the target areas of interest in the map comprises:in response to changes in the map data, determining the areas of interest corresponding to the positions of the changes as the target areas of interest.4. The method as claimed in claim 1 , wherein the map data comprises raw environmental data and/or map-formatted data claim 1 ,wherein the format of the raw environmental data comprises at least one of images, laser point cloud data and satellite positioning data.5. The method as claimed in claim 1 , wherein sending the data acquisition instruction to the data acquisition terminals to acquire the map data in the target areas of interest comprises:obtaining current positions of the data acquisition ...

LENS DRIVING DEVICE

A lens driving device includes a lens module, a first support frame, a second support frame sleeved on the first support frame, a support assembly for suspending the first support frame inside the second support frame, a first flexible printed circuit board (PCB) including folding portions, a second flexible PCB opposite to and independent from the first flexible PCB, and a driving assembly. Each folding portion includes a first fixing portion attached to the first support frame, a second fixing portion attached to the shell, and bent portions connecting the first fixing portion with the second fixing portion by bending. The two flexible PCBs are separately provided in the lens driving device to prevent the risk of disengagement when the two flexible PCBs move, and the folding portions prevent the first flexible PCB from being pulled by the movement of the lens module to be disconnected. 1. A lens driving device , comprising:a lens module;a first support frame configured to accommodate and carry the lens module;a second support frame sleeved on the first support frame and spaced apart from the first support frame;a support assembly configured to suspend the first support frame inside the second support frame in such a manner that the first support frame is rotatable relative to the second support frame about a first axis or a second axis, wherein the support assembly is rotatably connected to the first support frame along the first axis and rotatably connected to the second support frame along the second axis, and the first axis and the second axis are both perpendicular to an optical axis of the lens module;a shell covering the second support frame;a first flexible printed circuit board surrounding two adjacent sidewalls of the first support frame, wherein the first flexible printed circuit board comprises a plurality of folding portions that respectively correspond to the two adjacent sidewalls of the first support frame, wherein each of the folding portions ...

LENS DRIVING DEVICE

A lens driving device includes first and second support frames, lens barrel, anti-shake magnets, anti-shake coils, flexible PCB, metal sheets, and support assembly including support member and first and second guiding posts. Support member includes support plate and first and second support walls. First soft protruding rubbers are respectively provided at positions of top surface of first support frame corresponding first support walls, and second soft protruding rubbers are respectively provided at positions of inner wall of second support frame corresponding to two sides of each second support wall. Compared with the prior art, lens driving device of the present disclosure makes impact limit position of first support walls closer to deflection axis position in first direction, and makes impact limit positions of second support walls closer to deflection axis position in second direction to reduce speed of limit impact, thereby reducing risk of generating particles due to impact. 1. A lens driving device , comprising:a first support frame having a rectangular structure with a receiving space;a second support frame having a rectangular structure, the second support frame being sleeved on the first support frame and spaced apart from the first support frame;a lens barrel received in the receiving space and configured to install a lens;a support assembly comprising a support member, two first guiding posts, and two second guiding posts;at least two anti-shake magnets fixed to adjacent sidewalls of the first support frame, respectively;at least two anti-shake coils fixed to adjacent sidewalls of the second support frame, respectively;a flexible printed circuit board fixed to an outer peripheral side of the second support frame and electrically connected to the at least two anti-shake coils; andat least two metal sheets, each of the at least two metal sheets being opposite to and spaced apart from one of the at least two anti-shake magnets, and one of the at least two ...

CAMERA LENS

A camera lens includes a mounting housing, a lens module, an image stabilization module, first and second support shafts fixed to the mounting housing opposite to each other along one of diagonals of the mounting housing, and third and fourth support shafts fixed to the frame opposite to each other along another diagonal of the mounting housing. The mounting housing is formed by sequentially connecting first to fourth frame plates. The image stabilization module includes a frame, a movable frame, first and second image stabilization coils, and first and second magnets. The movable frame has first to fourth rotation holes. The first to fourth support shafts are respectively rotatably fit within the first to fourth rotation holes. The camera lens of the present disclosure can solve the problems of great process difficulty and high cost in the related art when the camera lens performs the optical image stabilization. 1. A camera lens comprising:a mounting housing;a lens module accommodated within the mounting housing;an image stabilization module for driving the lens module to rotate;a first support shaft and a second support shaft that are fixed to the mounting housing opposite to each other along one of diagonals of the mounting housing; anda third support shaft and a fourth support shaft that are fixed to the frame opposite to each other along another one of the diagonals of the mounting housing,wherein the mounting housing is formed by sequentially connecting a first frame plate, a second frame plate, a third frame plate, and a fourth frame plate; and a frame for accommodating the lens module;', 'a movable frame for movably suspending the frame in the mounting housing;', 'a first image stabilization coil fixed onto the first frame plate;', 'a second image stabilization coil fixed onto the second frame plate;', 'a first magnet fixed onto the frame relative to the first image stabilization coil; and', 'a second magnet fixed onto the frame relative to the second image ...

LENS DRIVING DEVICE

The present invention provides a lens driving device including a first supporting framework, a second supporting framework, a lens barrel, a bracket assembly which is rotatably connected with the first supporting framework, the first supporting framework is rotatably connected with the second supporting framework; anti-shake magnets fixed on two adjacent first side walls; anti-shake coils fixed on two adjacent second side walls; a flexible printed circuit fixed at a peripheral side of the second supporting framework and electrically connected with the anti-shake coils; and metal sheets respectively opposite to and spaced from two anti-shake magnets and generating mutual magnetic attraction with the anti-shake magnets. Compared with the related art, the lens driving device of the present invention has a simple structure and low production cost. 1. A lens driving device comprising:a first supporting framework enclosed by a first side wall into a rectangular structure having an accommodating space;a second supporting framework enclosed by a second side wall into a rectangular structure, wherein the second supporting framework is sleeved on the first supporting framework and spaced apart from the first supporting framework;a lens barrel accommodated in the accommodating space, wherein the lens barrel is connected with the first supporting framework and configured for mounting a lens;a bracket assembly which is rotatably connected with the first supporting framework in such a way that the first supporting framework is rotatable around a first direction relative to the bracket assembly, and the bracket assembly is rotatably connected with the second supporting framework and suspends the first supporting framework in the second supporting framework in such a way that the bracket assembly is capable of driving the first supporting framework to jointly rotate around a second direction relative to the second supporting framework, the first direction and the second direction ...

OFFLOADING A DISTRIBUTION SERVER TASK TO A MEDIA GATEWAY

A server offloads one or more tasks to a first media gateway. The server receives, from the first media gateway that is receiving a video stream of a television channel, a first message that indicates that the first media gateway is eligible to process a request for media content of the television channel that otherwise would be processed by the server. The server receives, from a second media gateway, a request for media content of the television channel. The server transmits, to the second media gateway, a redirection response that instructs the second media gateway to request the media content from the first media gateway. 1. A method in a server for offloading one or more tasks to a first media gateway , comprising:receiving, from the first media gateway that is receiving a video stream of a television channel, a first message that indicates that the first media gateway is eligible to process a request for media content of the television channel that otherwise would be processed by the server;receiving, from a second media gateway, a request for media content of the television channel; andtransmitting, to the second media gateway, a redirection response that instructs the second media gateway to request the media content from the first media gateway.2. The method of claim 1 , wherein the request for media content of the television channel is a channel change request to tune to the television channel.3. The method of claim 1 , wherein the request for media content of the television channel is a retransmission request for the television channel.4. The method of claim 1 , wherein the first media gateway is in a first customer premise and the second media gateway is in a second customer premise.5. The method of claim 1 , wherein the first media gateway and the second media gateway are in a same subnet.6. The method of claim 1 , wherein the first media gateway buffers the video stream of the television channel.7. The method of claim 1 , further comprising:receiving, ...

FIBER-BASED ORGANIC ELECTROCHEMICAL TRANSISTOR

An organic electrochemical transistor (OECT) that may be used as a biosensor is built up by layers applied to a monofilament. A first conducting layer applied to the monofilament includes generally cylindrical source and drain contacts with a gap therebetween. An electro-active layer of an organic material altering its electrical conductivity through a change in redox state is in electrical contact with the source and drain contacts, and has a transistor channel interface for contacting an electrolyte. A gate electrode is spaced apart from the first monofilament, and may comprise a cylindrical layer built up on another length of monofilament. 1. An electrochemical transistor device comprising:a first monofilament; the first conducting layer comprises a source contact and a drain contact and includes a gap between the source contact and the drain contact,', 'the electro-active layer is in electrical contact with the source contact and the drain contact,', 'the electro-active layer has a transistor channel interface for contacting an electrolyte, and', 'the electro-active layer is an organic material having an electrical conductivity altered by a change in redox state of the electro-active layer; and, 'a first conducting layer and an electro-active layer that are substantially coaxial with, and extend circumferentially about, the first monofilament, wherein'}a gate electrode spaced from the first monofilament, wherein current flow between the source contact and the drain contact is controllable by a voltage applied to the gate electrode.2. The electrochemical transistor device of claim 1 , whereinthe first conducting layer abuts the first monofilament, andthe electro-active layer fills the gap.3. The electrochemical transistor device of claim 2 , wherein the electro-active layer at least partially covers the source and drain contacts.4. The electrochemical transistor device of claim 1 , further comprising a dielectric layer that is substantially coaxial with claim 1 , ...

WATERBORNE POLYURETHANE DISPERSION AND METHOD FOR PREPARING THE SAME

A waterborne polyurethane dispersion is provided. The waterborne polyurethane dispersion comprises residual moiety of a hydroxy-terminated siloxane compound in the main chain and exhibits good anti-stickiness while retaining superior mechanical properties. A laminated synthetic leather article prepared with said waterborne polyurethane dispersion as well the method for preparing the synthetic leather article are also provided. 2. The waterborne polyurethane dispersion according to claim 1 , wherein the one or more compounds having at least two isocyanate groups are selected from the group consisting of:{'sub': 4', '12', '6', '15', '7', '15, 'a) C-Caliphatic polyisocyanates comprising at least two isocyanate groups, C-Ccycloaliphatic or aromatic polyisocyanates comprising at least two isocyanate groups, C-Caraliphatic polyisocyanates comprising at least two isocyanate groups, and a combination thereof; and'}{'sub': 2', '16', '6', '15', '7', '15', '2', '10', '2', '10', '2', '10, 'b) an isocyanate prepolymer prepared by reacting one or more polyisocyanates of a) with one or more isocyanate-reactive components selected from the group consisting of C-Caliphatic polyhydric alcohols comprising at least two hydroxy groups, C-Ccycloaliphatic or aromatic polyhydric alcohols comprising at least two hydroxy groups, C-Caraliphatic polyhydric alcohols comprising at least two hydroxy groups, polyester polyols having a molecular weight from 500 to 5,000, polycarbonate diols having a molecular weight from 200 to 5,000, polyetherdiols having a molecular weight from 200 to 5,000, Cto Cpolyamine comprising at least two amino groups, Cto Cpolythiol comprising at least two thiol groups, C-Calkanolamine comprising at least one hydroxyl group and at least one amino groups, and a combination thereof, with the proviso that the isocyanate prepolymer comprises at least two free isocyanate terminal groups.'}3. The waterborne polyurethane dispersion according to claim 1 , wherein the content of ...

TWO-COMPONENT ADHESIVE COMPOSITIONS, ARTICLES PREPARED WITH SAME AND PREPARATION METHODS THEREOF

A two-component adhesive composition is provided. The two-component adhesive composition comprises an isocyanate component, an isocyanate-reactive component and an amine-epoxy adduct, and can achieve superior adhesion strength between the adhesive and a substrate like metal alloy substrate. A laminated article prepared with said composition, a method for preparing the article and the use of the amine-epoxy adduct as adhesion promoter in a two-component polyurethane adhesive composition are also provided. 1. A two-component adhesive composition , comprising(A) an isocyanate component comprising one or more compounds having at least two isocyanate groups; and(B) an isocyanate-reactive component comprising one or more compounds having at least two isocyanate-reactive groups,wherein the two-component adhesive composition further comprises an amine-epoxy adduct derived from the reaction between:(i) at least one primary or secondary amine selected from the group consisting of aliphatic monoamine, aliphatic diamine, aliphatic triamine, cycloaliphatic monoamine, cycloaliphatic diamine, cycloaliphatic triamine, araliphatic monoamine, araliphatic diamine, araliphatic triamine, aromatic monoamine, aromatic diamine, aromatic triamines, and the combinations thereof; and(ii) at least one epoxy compound selected from the group consisting of aliphatic, cycloaliphatic and aromatic, mono-, di- or polyepoxy compounds.2. The two-component adhesive composition according to claim 1 , wherein the one or more compounds having at least two isocyanate groups are selected from the group consisting of:{'sub': 4', '12', '6', '15', '7', '15, 'a) C-Caliphatic polyisocyanates comprising at least two isocyanate groups, C-Ccycloaliphatic or aromatic polyisocyanates comprising at least two isocyanate groups, C-Caraliphatic polyisocyanates comprising at least two isocyanate groups, and a combination thereof; and'}{'sub': 2', '16', '6', '15', '7', '15', '2', '10', '2', '10', '2', '10, 'b) an isocyanate ...

LENS DRIVING DEVICE

A lens driving device includes fixing bracket, first support frame sleeved on the fixing bracket, second support frame sleeved on the first support frame, rotation assembly configured to make the fixing bracket rotate relative to the first support frame about a first direction and the first support frame rotate relative to the second support frame about a second direction, driving assembly for driving fixing bracket to rotate relative to first support frame about the first direction and driving the first support frame to rotate relative to the second support frame about the second direction, flexible printed circuit board, first elastic support components, and second elastic support components. The lens driving device increases spacing between adjacent two of crossing portions of the shape memory wires so that the shape memory wires have enough space for the movement, preventing the shape memory wires from being interfered with each other during the movement. 1. A lens driving device , comprising:a fixing bracket having a rectangular structure with a receiving space surrounded by sidewalls, the receiving space being configured to install a lens module;a first support frame having a rectangular structure surrounded by first sidewalls, the first support frame being sleeved on the fixing bracket and spaced apart from the fixing bracket;a second support frame having a rectangular structure surrounded by second sidewalls, the second support frame being sleeved on the first support frame and spaced apart from the first support frame;a rotation assembly, wherein the fixing bracket is rotatably connected to the first support frame through the rotation assembly in such a manner that the fixing bracket is rotatable relative to the first support frame about a first direction; the first support frame and the second support frame are rotatably connected to each other through the rotation assembly in such a manner that the first support frame is rotatable relative to the second ...

PHOTOGRAPHING APPARATUS AND ELECTRONIC DEVICE

A photographing apparatus and an electronic device are provided. The photographing apparatus includes a frame assembly, a first movement assembly, first support members, a second movement assembly, second support members, and a lens module. The frame assembly is provided with a receiving cavity. The first movement assembly is suspended in the receiving cavity, and a movement cavity is provided inside the first movement assembly. The first support members are each arranged at least partially in a respective first movement groove and abut against the first movement assembly and the frame assembly. The first movement grooves adapted to the first movement assembly and the second movement grooves adapted to the second movement assembly are provided such that the photographing apparatus is of a compact structure on condition that the lens module can rotate about the first axis of rotation and/or the second axis of rotation. 1. A photographing apparatus , comprising:a frame assembly provided with a receiving cavity;a first movement assembly suspended in the receiving cavity, a movement cavity being provided inside the first movement assembly;a plurality of first support members abutting against the first movement assembly and the frame assembly, such that the first movement assembly is rotatable about a first axis of rotation relative to the frame assembly;a second movement assembly suspended in the movement cavity;a plurality of second support members abutting against the second movement assembly and the first movement assembly, such that the second movement assembly is rotatable about a second axis of rotation relative to the first movement assembly, the second axis of rotation being perpendicular to the first axis of rotation; anda lens module connected to the second movement assembly, the first axis of rotation and the second axis of rotation being both perpendicular to an optical axis of the lens module.2. The photographing apparatus as described in claim 1 , further ...

LENS DRIVE DEVICE AND ELECTRONIC TERMINAL

A lens drive device and an electronic terminal are provided. The lens drive device includes a housing, a holder, permanent magnets, a lens barrel, a drive coil, an elastic assembly, and a circuit board assembly. The lens barrel is arranged in the holder in such a way that the lens barrel is movable in an optical axis direction of the lens. The elastic assembly is connected to the lens barrel and the holder separately and is used for supporting the lens barrel to move in the optical axis direction. The whole stroke of the lens barrel is increased so that the lens drive device of the present invention has a better performance. It is also possible to reduce the thickness of the lens drive device of the present invention with the stroke unchanged, such that the structure is more compact. 1. A lens drive device , comprising:a housing having a receiving space;a holder received and fixed in the receiving space;permanent magnets fixed to the holder;a lens barrel for receiving a lens, the lens barrel being arranged in the holder in such a way that the lens barrel is movable in an optical axis direction of the lens;a drive coil fitted over an outer peripheral face of the lens barrel and opposite the permanent magnets fixed to the holder;an elastic assembly connected to the lens barrel and the holder separately and used for supporting the lens barrel to move in the optical axis direction; anda circuit board assembly received and fixed in the receiving space and electrically connected to the drive coil,wherein the lens barrel comprises a first surface connected to the elastic assembly and close to an object side, and the holder comprises a second surface connected to the elastic assembly and close to the object side, the second surface being closer to the object side than the first surface; and the lens barrel comprises a third surface connected to the elastic assembly and close to an image side, and the holder comprises a fourth surface connected to the elastic assembly and ...

LENS DRIVING DEVICE

A lens driving device includes a fixing bracket; first and second support frames; a rotation assembly including first and second rolling balls so that the fixing bracket and the first support frame are spaced apart from each other and form a rotational connection about a first direction, and the first and second support frames are spaced apart from each other and form a rotational connection about a second direction; a driving assembly for driving the fixing bracket to rotate relative to the first and second support frames about the first direction and for driving the first support frame to rotate relative to the second support frame about the second direction; a flexible circuit board; and first and second elastic support components. The lens driving device reduces the height of the overall structure, and effectively reduces the height of the lens driving device. 1. A lens driving device , comprising:a fixing bracket having a rectangular structure with a receiving space, the receiving space being configured to install a lens module;a first support frame having a rectangular structure and sleeved on an outer periphery of the fixing bracket, the first support frame being spaced apart from the fixing bracket;a second support frame having a rectangular structure and sleeved on an outer periphery of the first support frame, the second support frame being spaced apart from the first support frame;a rotation assembly comprising at least one first rolling ball and at least one second rolling ball;a driving assembly comprising at least two shape memory wires;a flexible circuit board electrically connected to the at least two shape memory wires;at least one first elastic support component configured to elastically connect the fixing bracket with the first support frame and providing a rotation restoring force for the fixing bracket to rotate relative to the first support frame about a first direction; andat least one second elastic support component configured to elastically ...

PHOTOGRAPHING LENS

A photographing lens is provided, including a mounting framework, a lens module and an image stabilization module, where the image stabilization module includes a movable holder, a frame, a first rotation assembly, a second rotation assembly, a first elastic member, a second elastic member, a third elastic member and a fourth elastic member; the first elastic member includes a first fixing piece, a second fixing piece, and a first elastic piece connected between the first fixing piece and the second fixing piece; the second elastic member includes a third fixing piece, a fourth fixing piece, and a second elastic piece connected between the third fixing piece and the fourth fixing piece. The present invention solves the technical problems of the complex structure and increased thickness of the photographing lens for realizing the rotational reset of the lens module in the related art. 1. A photographing lens , comprising:a mounting framework having a first diagonal and a second diagonal;a lens module received in the mounting framework; andan image stabilization module for driving the lens module to rotate, the image stabilization module comprising:a movable holder suspended in the mounting framework,a frame used for receiving the lens module and suspended in the movable holder,a first rotation assembly arranged between the mounting framework and the movable holder along the first diagonal, anda second rotation assembly arranged between the movable holder and the frame along the second diagonal,wherein the image stabilization module further comprises a first elastic member and a second elastic member oppositely arranged at two corners of the mounting framework along the first diagonal, and a third elastic member and a fourth elastic member oppositely arranged at two corners of the movable holder along the second diagonal;the first elastic member comprises a first fixing piece connected to the mounting framework, a second fixing piece connected to the movable holder, ...

METHOD AND APPARATUS FOR AUTOMATIC CROSS-SYSTEM PROGRAM DEBUGGING

The present invention discloses a method and apparatus for automatic cross-system program debugging. One embodiment of the present invention provides a method for cross-system program debugging. The method comprises: determining a first breakpoint in a first debugging session of a first system; determining a second breakpoint in a second debugging session of a second system, the second system being different from the first system; and responsive to a user performing a debugging action of associating the first breakpoint with the second breakpoint in the first debugging session and the second debugging session, recording an association between the first breakpoint and the second breakpoint for automating the program debugging across the first system and the second system. There is further described a corresponding apparatus. 1. A method of automatic cross-system program debugging comprising:determining a first breakpoint in a first debugging session of a first system;determining a second breakpoint in a second debugging session of a second system, the second system being different from the first system; andresponsive to a user performing a debugging action of associating the first breakpoint with the second breakpoint in the first debugging session and the second debugging session, recording an association between the first breakpoint and the second breakpoint for automating program debugging across the first system and the second system.2. The method according to claim 1 , further comprising:recording an action performed by the user after debugging associated with the second breakpoint, the first breakpoint being prior to the second breakpoint.3. The method according to claim 2 , wherein the recording an action performed by the user after debugging associated with the second breakpoint comprises:recording whether the user continues execution of the first debugging session or the second debugging session after the debugging associated with the second breakpoint.4. ...

HISTONE ACETYLTRANSFERASE MODULATORS AND USES THEREOF

The invention provides compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a compound that modulates HAT to a subject. 24. The method of claim 23 , wherein the subject exhibits abnormally elevated levels of amyloid beta plaques.25. The method of or wherein the subject is afflicted with Alzheimer's disease claim 23 , Lewy body dementia claim 23 , inclusion body myositis claim 23 , or cerebral amyloid angiopathy.26. The method of any of - claim 23 , wherein the Aβ protein deposit comprises an Aβisomer claim 23 , an Aβisomer claim 23 , or a combination thereof.27. A method for treating Alzheimer's Disease in a subject claim 23 , the method comprising administering to a subject a therapeutic amount of a compound of any of - or a pharmaceutical composition comprising a compound of any of -.28. A method for increasing memory retention in a subject afflicted with a neurodegenerative disease claim 23 , the method comprising administering to a subject a therapeutic amount of a compound of any of - or a pharmaceutical composition comprising a compound of any of -.29. A method for increasing synaptic plasticity in a subject afflicted with a neurodegenerative disease claim 23 , the method comprising administering to a subject a therapeutic amount of a compound of any of - or a composition comprising a compound of any of - that increases histone acetylation in the subject.30. A method for treating a neurodegenerative disease in a subject claim 23 , the method comprising administering to a subject a therapeutic amount of a compound of any of - or a pharmaceutical composition comprising a compound of any of - claim 23 , thereby treating the neurodegenerative disease in the subject.31. A method for ...

HISTONE ACETYLTRANSFERASE ACTIVATORS AND USES THEREOF

The invention provides for a method for screening compounds that bind to and modulate a histone acetyltransferase protein. The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a HAT-activating compound to a subject. 2. The method of claim 1 , wherein the subject exhibits abnormally elevated levels of amyloid beta plaques.3. The method of claim 1 , wherein the subject is afflicted with Alzheimer's disease claim 1 , Lewy body dementia claim 1 , inclusion body myositis claim 1 , or cerebral amyloid angiopathy.4. The method of claim 1 , wherein the Aβ protein deposit comprises an Aβ40 isomer claim 1 , an Aβ42 isomer claim 1 , or a combination thereof.6. A method for treating Alzheimer's Disease claim 1 , the method comprising administering to a subject a therapeutic amount of a pharmaceutical composition comprising a HAT activator compound.13. A method for ameliorating symptoms of Parkinson's Disease claim 1 , the method comprising administering to a subject a therapeutic amount of a pharmaceutical composition comprising a HAT activator compound.15. A method for treating Huntington's Disease claim 1 , the method comprising administering to a subject a therapeutic amount of a pharmaceutical composition comprising a HAT activator compound.16. The method of claim 1 , wherein the effective amount is at least about 1 mg/kg body weight claim 1 , at least about 2 mg/kg body weight claim 1 , at least about 3 mg/kg body weight claim 1 , at least about 4 mg/kg body weight claim 1 , at least about 5 mg/kg body weight claim 1 , at least about 6 mg/kg body weight claim 1 , at least about 7 mg/kg body weight claim 1 , at least about 8 mg/kg body weight claim 1 , at least about 9 mg/kg body weight claim 1 , at least about 10 mg/kg body weight claim 1 , at least about 15 mg/kg body weight claim 1 ...

FILE SHARING USING REMOTE APPLICATIONS

Techniques are disclosed herein for file sharing using remote applications. One embodiment provides a computer-implemented method that includes receiving, at a computing device, a selection of a reference for accessing the file, where the reference includes a first identifier specifying the file stored on a host server remotely located with respect to the computing device and a second identifier specifying an application that is running on the host server and that is configured to open files of a same type as the file. The method further includes establishing a remote connection to the application specified by the second identifier, by connecting to the host server and causing the application to be launched on the host server. In addition, the method includes causing the application to open the file specified by the first identifier and the user interface of the application to be remoted to the computing device. 1. A method for sharing a file , the method comprising:receiving, at a computing device, a selection of a reference for accessing the file, wherein the reference includes a first identifier specifying the file stored on a host server remotely located with respect to the computing device and a second identifier specifying an application that is running on the host server and that is configured to open files of a same type as the file;establishing a remote connection to the application specified by the second identifier, by connecting to the host server and causing the application to be launched on the host server; andcausing the application to open the file specified by the first identifier and the user interface of the application to be remoted to the computing device.2. The method of claim 1 , further comprising:launching, in the computing device, a remote access client in response to receiving the selection of the reference,wherein the remote access client connects to the application that is operating on a virtualized workload container on the host server ...

Process For Making Powder Alloys Containing Cadmium And Selenium

A process for preparing alloy products powders is described using a self-sustaining or self-propagating SHS-type combustion process. Binary, ternary and quaternary alloy having cadmium, selenium and optionally a third element X or Y selected from Group VIA (such as S or Te) or from group IIB (such as Zn or Hg). The alloy products may be doped or not with a wide variety of other elements. The process involves heating to ignition, maintaining an elevated temperature less than melting for homogenization, followed by cooling and crushing. An optional de-oxidation process may follow to further purify the alloy and balance the stoichiometry. 1. A process for making powder alloys containing cadmium and selenium , comprisingblending a mixture of cadmium particles and selenium particles, the cadmium and selenium particles having a size ranging from about 1 to about 600 microns;blending into the mixture a quantity of quenchant particles having a size ranging from about 1 to about 1000 microns;heating the mixture to an ignition temperature at a rate allowing the reaction to establish a self-propagation mode to form an alloy product;maintaining an inert environment at an elevated temperature less than a melting point of the alloy product for a time sufficient to ensure homogenization of the alloy product; andcooling and crushing the alloy product to form a homogeneous alloy powder.2. The process according to claim 1 , further comprising blending particles of an additional element into the mixture to form a ternary alloy of the formula CdSeX claim 1 , or CdYSe claim 1 , in which X is an element selected from group VIA; Y is an element selected from group IIB; u and w are numbers from 0.05 to 0.99.3. The process according to claim 2 , wherein Y is selected from Cd claim 2 , Zn claim 2 , and Hg and wherein X is selected from S and Te.5. The process according to claim 4 , wherein Y is selected from Cd claim 4 , Zn claim 4 , and Hg and wherein X is selected from S and Te.6. The ...

MODIFIED FILLER COMPOSITION, PULP AND PAPER USING SAME

A modified filler composition used in papermaking is provided. The modified filler composition contains microfibrillated cellulose, and filler having negative charge, and a cationic polymer. 1. A modified filler composition , comprising:filler having negative charge;microfibrillated cellulose having a dry weight of 0.1% to 10% of that of the filler, the microfibrillated cellulose being made by TEMPO catalytic oxidation method; andcationic polymer having a dry weight of 0.1% to 15% of that of the filler.2. The modified filler composition as claimed in claim 1 , wherein the microfibrillated cellulose has a carboxyl content of 0.06 to 1.7 mmol/g; the microfibrillated cellulose comprises water-soluble cellulose having a mass percentage on a dry solids basis of 0.1% to 50% and water-insoluble cellulose having a mass percentage on a dry solids basis of 10% to 99.9%.3. The modified filler composition as claimed in claim 2 , wherein the water-soluble celluloses comprises nanocrystalline cellulose claim 2 , nanofibrillated cellulose claim 2 , and oligosaccharide.4. The modified filler composition as claimed in claim 1 , wherein the filler is surface modified by a dispersant claim 1 , the dispersant has a weight of 0.001% to 5% of that of the filler; and the dispersant is selected from sodium polyacrylate claim 1 , sodium polycarboxylic acid claim 1 , sodium poly-allylsulfonate claim 1 , and derivatives thereof.5. The modified filler composition as claimed in claim 1 , wherein the cationic polymer is selected from cationic polysaccharide claim 1 , cationic polyacrylamide claim 1 , polyvinylamine claim 1 , polyethylene imine claim 1 , and derivatives thereof.6. The modified filler composition as claimed in claim 1 , wherein the cationic polymer has a molecular weight between 2×10and 2×10.7. The modified filler composition as claimed in claim 6 , wherein the cationic polymer has a molecular weight between 2×10and 1×10.8. The modified filler composition as claimed in claim 1 , ...

Modified filler composition and papermaking process using the same

A modified filler composition used in papermaking is provided. The modified filler composition contains microfibrillated cellulose, filler, and latex having a glass transition temperature of less than 20° C. The dry weight of the microfibrillated cellulose is about 0.1% to about 10% that of the filler; the dry weight of the latex is about 0.1% to about 15% that of the filler.

Method for detecting nucleic acid based on prokaryotic argonaute protein and application thereof

Provided are a method for detecting a nucleic acid based on prokaryotic Argonaute protein and an application thereof. In particular, provided is a system for detecting a target nucleic acid molecule. The system comprises guide ssDNA, a gene-editing enzyme Pyrococcus furiosus Argonaute (PfAgo), and a fluorescent reporter nucleic acid.

BENZOCROWN ETHER GRAFT POLYMER WITH LITHIUM ISOTOPIC SEPARATION EFFECT AND PREPARATION METHOD THEREOF

Disclosed in the present invention is a benzocrown ether graft polymer with a lithium isotopic separation effect and a preparation method thereof. The polymer is a benzocrown ether graft polymer formed by the linkage of chemical bonds, which takes the main chain of a polymer containing chloromethyl group, chloroformyl group or hydroxyl group as main chain, and takes a benzocrown ether as pendant group. The preparation process of the polymer comprises the following steps: preparing polymer solution with certain concentration by dissolving a polymer containing chloromethyl group, chloroformyl group or hydroxyl group in a solvent; then blending a catalyst and a benzocrown ether containing carboxyl group or aldehydyl group and dissolving in the polymer solution containing hydroxyl group, or blending an acid-binding agent and a benzocrown ether containing amino group or hydroxyl group and dissolving in the polymer solution containing chloromethyl group or chloroformyl group, reacting at a certain temperature and for a certain time, linking the benzocrown ether to the main chain of polymer by chemical bonds, and precipitating by adding a precipitating agent to obtain the graft polymer. The grafting polymer has excellent characteristic of lithium isotopic separation. 1. A graft polymer with lithium isotopic separation effect , characterized in that the graft polymer comprises main chain and pendant group , taking the main chain of a polymer containing chloromethyl group , chloroformyl group or hydroxyl group as main chain , the pendant group is a benzocrown ether , wherein in the graft polymer taking the main chain of a polymer containing hydroxyl as main chain , the content of pendant group is 0.1˜30 mmol/g , in the graft polymer taking the main chain of a polymer containing chloromethyl group or chloroformyl group as main chain , the content of pendant group is 0.1˜2.0 mmol/g.2. The graft polymer with lithium isotopic separation effect according to claim 1 , ...

DEPLOYING APPLICATIONS

A method, executed by a computer, for deploying an application includes receiving a deployment description that indicates the one or more deployment configurations and an artifact corresponding to a deployment, accessing a repository that contains the deployment configurations and the artifact that correspond to the deployment, enabling a user to select a subset of deployment configurations, and deploying the subset of deployment configurations and artifact to a processing environment. 1. A method for deploying an application , the method comprising:receiving a deployment description that indicates one or more deployment configurations and an artifact corresponding to a deployment;providing a template for translating a preconfigured deployment configuration;enabling a user to select a subset of deployment configurations, wherein at least one of the one or more deployment configurations is the preconfigured deployment configuration;translating the preconfigured deployment configuration according to the template to produce a compatible deployment configuration; anddeploying the subset of deployment configurations, the compatible deployment configuration, and the artifact to a processing environment.2. The method of claim 1 , further comprising enabling a user to customize a command template.3. The method of claim 1 , wherein deploying the subset of deployment configurations and the artifact to a processing environment comprises:generating commands to deploy each deployment configuration of the subset of deployment configurations; andexecuting the commands.4. (canceled)5. The method of claim 1 , wherein the template is provided by a user.6. The method of claim 1 , wherein a deployment configuration comprises a middleware application configuration.7. The method of claim 1 , wherein the deployment description is an Extensible Markup Language file. The present invention relates generally to deploying applications, and more specifically, to deploying applications with ...

DEPLOYING APPLICATIONS

A method, executed by a computer, for deploying an application includes receiving a deployment description that indicates the one or more deployment configurations and an artifact corresponding to a deployment, accessing a repository that contains the deployment configurations and the artifact that correspond to the deployment, enabling a user to select a subset of deployment configurations, and deploying the subset of deployment configurations and artifact to a processing environment. A computer program product and computer system corresponding to the above method are also disclosed herein. 17-. (canceled)8. A computer system for deploying an application , the computer system comprising:one or more computer processors;one or more computer readable storage media;program instructions stored therein for execution by at least one of the one or more computer processors, the program instructions comprising instructions to:provide a template for translating a preconfigured deployment configuration;receive a deployment description that indicates one or more deployment configurations and an artifact corresponding to a deployment, wherein at least one of the one or more deployment configurations is the preconfigured deployment configuration;translate the preconfigured deployment configuration according to the template to produce a compatible deployment configuration;enable a user to select a subset of deployment configurations; anddeploy the subset of deployment configurations, the compatible deployment configuration, and the artifact to a processing environment.9. The computer system of claim 8 , further comprising instructions to enable a user to customize a command template.10. The computer system of claim 8 , wherein instructions to deploy the subset of deployment configurations and the artifact to a processing environment comprise instructions to:generate commands to deploy each deployment configuration of the subset of deployment configurations; andexecute the commands ...

AZETIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF

The present invention relates to an azetidine derivative for use as a Janus kinase (JAK) inhibitor, a drug composition comprising same, a preparation method therefor, and a use thereof in the treatment of JAK-related diseases comprising, for example, inflammatory diseases, autoimmune diseases, and cancers. 7. The method according to claim 1 , wherein the JAK-related disease is a member selected from the group consisting of an inflammatory disease claim 1 , autoimmune disease claim 1 , and cancer.8. The method according to claim 1 , wherein the JAK-related disease is a member selected from the group consisting of an inflammatory bowel disease claim 1 , lupus claim 1 , and psoriasis.9. The method according to claim 6 , wherein the JAK-related disease is a member selected from the group consisting of an inflammatory disease claim 6 , autoimmune disease claim 6 , and cancer.10. The method according to claim 6 , wherein the JAK-related disease is a member selected from the group consisting of an inflammatory bowel disease claim 6 , lupus claim 6 , and psoriasis.11. The method according to claim 1 , wherein the therapeutically effective amount is a member selected from the group consisting of about 0.01 mg to about 1000 mg claim 1 , about 0.1-500 mg claim 1 , about 0.5-300 mg claim 1 , about 1-150 mg claim 1 , about 1-50 mg or about 25 mg.12. The method according to claim 1 , wherein the therapeutically effective amount is a member selected from the group consisting of about 0.1 mg claim 1 , about 0.25 mg claim 1 , about 0.5 mg claim 1 , about 1 mg claim 1 , about 1.5 mg claim 1 , about 2 mg claim 1 , about 3 mg claim 1 , about 4 mg claim 1 , about 5 mg claim 1 , about 6 mg claim 1 , about 8 mg or about 10 mg.13. The method according to claim 1 , wherein the therapeutically effective amount is a member selected from the group consisting of about 0.1 mg claim 1 , about 0.25 mg claim 1 , about 0.5 mg claim 1 , about 1 mg claim 1 , about 1.5 mg claim 1 , about 2 mg claim 1 , ...

Devices and methods for making polycrystalline alloys

A process for preparing alloy products is described using a self-sustaining or self-propagating SHS-type combustion process with point-source ignition, preferably a laser, in a pressurized vessel. Binary, ternary and quaternary alloys can be formed with control over polycrystalline structure and bandgap. Methods to tune the bandgap and the alloys formed are described. The alloy products may be doped. Preferably sulfides, tellurides or selenides are formed. Cooling during reaction takes place.

PRESSING MEMBER AND MACHINE WITH PRESSING MEMBER

A pressing member includes a base, a first pressing portion, and a second pressing portion. The first pressing portion and the second pressing portion are arranged on a same surface of the base. The base is provided with a first hole. The first pressing portion includes a first contact surface facing away from the base. The first contact surface defines a second hole extending toward the base and communicating with the first hole to cooperatively define a channel. The second pressing portion includes a second contact surface facing away from the base. The second contact surface and the first contact surface are arranged on a same plane. 1. A pressing member comprising:a base provided with a first hole;a first pressing portion arranged on a surface of the base, the first pressing portion comprising a first contact surface facing away from the base, the first contact surface defining a second hole extending toward the base and communicating with the first hole to cooperatively define a channel; anda second pressing portion arranged on the surface of the base provided with the first pressing portion, the second pressing portion comprising a second contact surface facing away from the base, the second contact surface and the first contact surface arranged on a same plane.2. The pressing member of claim 1 , wherein:the surface of the base provided with the second pressing portion is provided with a receiving groove;a portion of the second pressing portion is received in the receiving groove; andthe second contact surface protrudes from the receiving groove.3. The pressing member of claim 2 , wherein:the base comprises a side surface provided with a guiding groove extending along the side surface toward the first pressing portion; andthe second pressing portion is movably arranged in the guiding groove.4. The pressing member of claim 3 , wherein:an extension direction of the guiding groove is perpendicular to an extension direction of the receiving groove; andthe guiding ...

METHOD AND APPARATUS FOR CONTROLLING AUTONOMOUS VEHICLE

A method and an apparatus for controlling an autonomous vehicle are provided according to the embodiments of the disclosure. The method includes: sending, in response to determining that a pedestrian is in a first target area, behavior prompt information representing prompting the pedestrian to make a corresponding behavior; determining whether a deceleration condition matching the behavior prompt information is satisfied based on acquired behavior information of the pedestrian; and sending control information for reducing a moving speed of the autonomous vehicle, in response to determining that the deceleration condition is satisfied and determining that a speed of the autonomous vehicle is greater than a preset deceleration threshold. According to the embodiments, deceleration control of the autonomous vehicle is achieved based on the response of the pedestrian to the behavior prompt information. 1. A method for controlling an autonomous vehicle , the method comprising:sending, in response to determining that a pedestrian is in a first target area, behavior prompt information representing prompting the pedestrian to make a corresponding behavior;determining whether a deceleration condition matching the behavior prompt information is satisfied based on acquired behavior information of the pedestrian; andsending control information for reducing a moving speed of the autonomous vehicle, in response to determining that the deceleration condition is satisfied and determining that a speed of the autonomous vehicle is greater than a preset deceleration threshold.2. The method according to claim 1 , wherein the method further comprisessending control information for stopping a movement of the autonomous vehicle, in response to determining that the pedestrian is in a second target area and determining that the autonomous vehicle is in a moving state.3. The method according to claim 1 , wherein the behavior prompt information comprises information representing prompting the ...

LIGHT EMITTING DIODE CHIP STRUCTURE AND MANUFACTURING METHOD THEREFOR

A light emitting chip includes a first-type semiconductor layer, a light emitting layer, and a second-type semiconductor layer which are disposed in such order, a passivation layer, and a current spreading layer. The second-type semiconductor layer and the light emitting layer cooperate to form a mesa structure which partially exposes the first-type semiconductor layer. The mesa structure has a lateral surface over which the passivation layer is disposed. The current spreading layer is disposed in contact with the second-type semiconductor layer. A distance between peripheries of a contact surface of the current spreading layer and a top surface of the second-type semiconductor layer is not greater than 5 μm. A method for producing the chip is also disclosed. 1. A light emitting chip comprising:an electrically conductive first-type semiconductor layer;a light emitting layer disposed on an upward surface of said first-type semiconductor layer, and having opposite upper and lower surfaces that are distal from and proximal to said upward surface of said first-type semiconductor layer, respectively;an electrically conductive second-type semiconductor layer disposed on said upper surface of said light emitting layer, and having opposite top and bottom surfaces that are distal from and proximal to said upper surface of said light emitting layer, respectively, said second-type semiconductor layer and said light emitting layer cooperating to form a mesa structure which partially exposes said upward surface of said first-type semiconductor layer, said mesa structure having a lateral surface that extends from said lower surface of said light emitting layer to said top surface of said second-type semiconductor layer;a passivation layer disposed over said lateral surface of said mesa structure; anda transparent current spreading layer disposed on said top surface of said second-type semiconductor layer, and having a contact surface in contact with said top surface of said ...

LASER-ANNEALED PEROVSKITE FILM AND METHOD FOR PREPARING THE SAME

The present disclosure provides a laser-annealing method for fabricating large-grain perovskite films for perovskite solar cells based on optimal conditions including laser wavelength, scanning speed and laser power. Compared with the conventional technology, the present laser-annealing method provides the laser-annealed perovskite films with better crystallinity and larger grains thereby improving the photovoltaic performance of the perovskite solar cells. 1. A method for preparing a laser-annealed perovskite film by one or more laser beams comprising:providing an as-deposited perovskite film having an amorphous phase and comprising a plurality of perovskite crystallites, each perovskite crystallite being surrounded by the amorphous phase;determining a light wavelength, at which a light absorbance ratio of the plurality of perovskite crystallites to the amorphous phase in a spectral region is larger than a threshold value, the threshold value being 80% of a largest value of the light absorbance ratio in the spectral region;selecting a wavelength of each laser beam to be the determined light wavelength such that the plurality of perovskite crystallites absorbs more energy from the one or more laser beams and attains higher temperature than the amorphous phase thereby inducing selective growth of the plurality of perovskite crystallites for improving crystallinity of the laser-annealed perovskite film and increasing an average grain size of the laser-annealed perovskite film;selecting a power and a scanning speed of each laser beam such that when an area of the as-deposited perovskite film is scanned by an individual laser beam with the selected wavelength, a surface temperature of the area is raised to a crystallization temperature of the as-deposited perovskite film for improving the crystallinity and increasing the average grain size; andscanning one or more surfaces of the perovskite film by the one or more laser beams with the selected wavelength, the selected ...

MINING MACHINE MANAGEMENT METHOD AND SYSTEM

The embodiments of the present application provide a mining machine management method and system. The method includes: determining the number of target IPs corresponding to the mining machine written in configuration information and an update frequency of data, and starting the corresponding coroutine to collect the data from the mining machine corresponding to the target IPs based on the number of the target IPs and the update frequency of the data; and uploading the data to a local server, and uploading the data to a cloud server by the local server. 1. A mining machine management method , comprising:determining the number of target IPs corresponding to a mining machine written in configuration information and an update frequency of data, and starting a corresponding coroutine to collect data from the mining machine corresponding to the target IPs based on the number of the target IPs and the update frequency of the data; anduploading the data to a local server, and uploading the data by the local server to a cloud server.2. The method according to claim 1 , wherein the step of determining the number of target IPs corresponding to a mining machine written in configuration information and an update frequency of data claim 1 , and starting a corresponding coroutine to collect the data from the mining machine corresponding to the target IPs based on the number of the target IPs and the update frequency of the data comprises:determining the number of coroutines to be started according to the number of target IPs;determining a scheduling interval of each coroutine according to the number of coroutines to be started and the update frequency;starting the corresponding number of coroutines; andscheduling the coroutine to collect the data from the target IPs according to the scheduling interval.3. The method according to claim 2 , wherein the step of scheduling the coroutine to collect the data from the target IPs according to the scheduling interval comprises:scheduling ...

CERAMIC TIP FOR GAS-ASSISTED ELECTROSURGICAL PROBE

An apparatus for gas-assisted electrosurgery having a gas-assisted electrosurgical probe comprising a tube and an electrode within said tube, wherein a distal end portion of said electrode extends from an opening at a distal end of said tube and an electrically insulating tip connected to a distal end of said electrode. The electrically insulating tip has a substantially hemispherical distal end portion having a radius rand a proximal portion having a circular cross-section and a central axis of a length l, wherein 1>r. 1. A probe for gas-assisted electrosurgery comprising:a gas-assisted electrosurgical probe comprising a tube and an electrode within said tube, wherein a distal end portion of said electrode extends from an opening at a distal end of said tube; [{'sub': 'c', 'a substantially hemispherical distal end portion having a radius r;'}, {'sub': '1', 'a proximal portion having a circular cross-section and a central axis of a length L;'}, {'sub': 1', 'c, 'wherein L>r.'}], 'an electrically insulating tip connected to a distal end of said electrode, said electrically insulating tip comprising2. The probe for gas-assisted electrosurgery according to claim 1 , further comprising a fillet between said substantially distal end portion and said proximal portion.3. The probe for gas-assisted electrosurgery according to claim 2 , wherein said proximal portion has an outer surface having a plurality of portions with at least two of said plurality of sections having a different radii of curvature.4. The probe for gas-assisted electrosurgery according to claim 3 , wherein said at least two radii of curvature decrease from a proximal end of said electrically insulating tip to said fillet.5. The probe for gas-assisted electrosurgery according to claim 1 , wherein said proximal portion has an outer surface having a varying radius of curvature.6. The probe for gas-assisted electrosurgery according to claim 1 , wherein said proximal portion has a straight outer surface.7. The ...

LATENT CATALYST MIXTURE FOR EPOXY/ANHYDRIDE COMPOSITIONS

A composition comprising, consisting of, or consisting essentially of a) an epoxy resin; b) an anhydride hardener; and c) a latent catalyst which is a mixture of i) a Lewis acid catalyst; and ii) an imidazolium acetate catalyst, is disclosed. 1. A composition comprisinga) an epoxy resin;b) an anhydride hardener; and i) a Lewis acid catalyst; and', 'ii) an imidazolium acetate catalyst., 'c) a latent catalyst which is a mixture of'}2. The composition of claim 1 , wherein the epoxy resin is present in the composition in an amount in the range of from 30 to 95 phr and the anhydride hardener is present in the composition in an amount in the range of from 1 to 60 phr.3. The composition of any one of or wherein the imidazolium acetate catalyst is selected from the group consisting of 1-ethyl claim 1 , 2-methyl-imidazolium acetate claim 1 , 1 claim 1 ,3-di-tert-butyl-imidazolium acetate claim 1 , 1 claim 1 ,3-didamantyl-imidazolium acetate claim 1 , 1 claim 1 ,3-diisopropyl-imidazolium acetate claim 1 , and 1-butyl-3-methylimidazolium acetate.4. The composition of any one of the preceding claims claim 1 , wherein the Lewis acid catalyst is chromium (III) carboxylate.5. The composition of any one of the preceding claims claim 1 , wherein the latent catalyst is present in the composition in an amount in the range of from 0.1 to 15 phr.6. The composition of any one of the preceding claims claim 1 , wherein the ratio of Lewis acid catalyst to imidazolium acetate catalyst is in the range of from 1:10 to 10:1.7. A process of making the composition of any one of the preceding claims claim 1 , said process comprisinga) admixing i) the epoxy resin; ii) the anhydride hardener; and iii) the latent catalyst; andb) activating the latent catalyst.8. A process in accordance with claim 7 , wherein the latent catalyst is activated in step b) using heat.9. A pultrusion process using the composition of any one of -.10. A composite prepared by the pultrusion process of . The present invention ...

DUAL-DEVICE PHOTOSENSITIVE DETECTION UNIT BASED ON COMPOSITE DIELECTRIC GATE, DETECTOR AND METHOD THEREOF

A photosensitive detection unit has a composite dielectric gate MOS-C portion and a composite dielectric gate MOSFET portion. The two portions are formed above a same P-type semiconductor substrate, and share a charge coupled layer. A plurality of the photosensitive detection units are arranged on a same P-type semiconductor substrate in form of an array to obtain a detector. Adjacent unit pixels in the detector are isolated by deep trench isolation regions and P-type injection regions below the isolation regions. During the detection, the P-type semiconductor substrate in the composite dielectric gate MOS-C portion senses light and then couples photoelectrons to the charge coupled layer, and photoelectronic signals are read by the composite dielectric gate MOSFET portion. 1. A dual-device photosensitive detection unit based on a composite dielectric gate , comprising a composite dielectric gate MOS-C portion having a light sensing function and a composite dielectric gate MOSFET portion having an information reading function , the two portions being formed above a same P-type semiconductor substrate;the composite dielectric gate MOS-C portion comprises a charge coupled layer, a first top dielectric layer and a first control gate which are all successively stacked above the P-type semiconductor substrate, wherein an N-type injection layer is formed in the P-type semiconductor substrate and below the charge coupled layer;the composite dielectric gate MOSFET portion comprises a bottom dielectric layer, the charge coupled layer, a second top dielectric layer and a second control gate which are all successively stacked above the P-type semiconductor substrate, wherein an N-type source region and an N-type drain region are formed in the P-type semiconductor substrate and on a side close to the bottom dielectric layer, and a threshold adjustment injection region is formed in the P-type semiconductor substrate and below the bottom dielectric layer; and{'sup': '+', 'in the P ...

Converting database language statements between dialects

A system receives a source database language statement according to a first dialect, determines a pattern of the source database language statement, the pattern comprising an abstract representation of the source database language statement, and checks whether the determined pattern is present in a cache of translations between patterns according to the first dialect and corresponding patterns according to a second dialect different from the first dialect. In response to the determined pattern being present in the cache of translations, the system converts, using a corresponding translation in the cache of translations, the source database language statement according to the first dialect to a respective target database language statement according to the second dialect.

Integrated chamber for vacuum coating

The present disclosure discloses an integrated chamber for vacuum coating, including an integrated chamber composed of a chamber top plate, four chamber side plates and a chamber bottom plate; wherein a baffle is provided in the integrated chamber, dividing the integrated chamber into a preheating chamber and a processing chamber; the baffle is provided with an opening for a workpiece to pass through, and a sealing door for blocking the opening is provided in the preheating chamber; the sealing door is hermetically fitted with the baffle, and the sealing door is connected with a first driving member so as to drive the sealing door to open and close. By integrating the preheating chamber and the processing chamber into an integrated chamber, the manufacturing process is improved and the assembly and maintenance are facilitated.

FOUR-DIMENSIONAL MULTI-PLANE BROADBAND IMAGING SYSTEM BASED ON NON-REENTRY QUADRATICALLY DISTORTED (NRQD) GRATING AND GRISM

Disclosed is a four-dimensional (4D: 3D+time) multi-plane broadband imaging apparatus capable of recording 3D multi-plane and multi-colour images simultaneously. The apparatus comprises: one or more non-reentry quadratically distorted (NRQD) gratings () which can produce a focal length and a spatial position corresponding to each diffraction order, thus simultaneously transmitting wavefront information between multiple object/image planes () and a single image/object plane (); a grism system () which can limit chromatically-induced lateral smearing by creating a collimated beam in which the spectral components are laterally displaced; a lens system () which is configured to adjust the optical path; and the optical detector(s) (). In an optical system, the multiple object/image planes (), the lens system (), the grism system (), the NRQD grating(s) (), the optical detector(s) () and the single image/object plane () are located on the same optical axis (). This simple, easy-to-use and compact apparatus can meet many different requirements and serve a large range of high throughput applications. 1. An apparatus for four-dimensional multi-plane broadband imaging comprising:one or more non-reentry quadratically distorted (NRQD) gratings, which are defined as QD gratings without re-entrant grooves, arranged in a multi-element optical system to produce a focal length and a spatial position associated with each diffraction order;one or more pairs of grisms arranged to manipulate the optical path in space by wavelength for correcting the chromatic dispersion of a broadband input beam generated by the NRQD grating(s);a lens system arranged to effectively modify the focal length of the optical system associated with each diffraction order of the NRQD grating(s) and manipulate the optical path to meet the design requirements of the grism system and,means for light detection.2. An apparatus according to wherein the NRQD grating is designed by a combination mask pattern which ...

telescopic rod connector and telescopic rod assembly

The present invention discloses a telescopic rod connector, which includes an outer sleeve, an inner sleeve and a screw rod. The screw rod has opposite a first end and a second end, and a rod body between them. The inner sleeve sleeves on the rod body and can rotate and slide along it, and the inner sleeve is provided with positioning convex strips. The outer sleeve includes a notch ring and a plurality of outer arc members extending from the notch ring. U-shaped notches are arranged between adjacent two the outer arc members; the outer sleeve is arranged on the outside of the inner sleeve and the notch ring is close to the first end, and the positioning convex strips are inserted into the U-shaped notches. The outer sleeve is rotated to drive the inner sleeve to slide along the rod body. 1. A telescopic rod connector , wherein comprising:a screw rod, said screw rod has opposite a first end and a second end, and a rod body between them,an inner sleeve, said inner sleeve sleeves on said rod body and can rotate and slide along said rod body, said inner sleeve is provided with positioning convex strips;an outer sleeve, said outer sleeve includes a notch ring and a plurality of outer arc members extending from said notch ring; U-shaped notches are arranged between adjacent two said outer arc members, and its number of said U-shaped notches is equal to that of said positioning convex strips; said outer sleeve is wrapped said inner sleeve and said notch ring is close to said first end, said positioning convex strips are inserted into said U-shaped notches, respectively;said outer sleeve is rotated to drive said inner sleeve to slide along said rod body, when said inner sleeve is sliding from said first end to said second end, said outer arc members are squeezed and opened, and when said inner sleeve is sliding from said second end to said first end, said outer arc members are closed up.2. The telescopic rod connector according to claim 1 , wherein a first helix and a ...

KDR AND VEGF/KDR BINDING PEPTIDES AND THEIR USE IN DIAGNOSIS AND THERAPY

The present invention provides polypeptides, peptide dimer, and multimeric complexes comprising at least one binding moiety for KDR or VEGF/KDR complex, which have a variety of uses wherever treating, detecting, isolating or localizing angiogenesis is advantageous. Particularly disclosed are synthetic, isolated polypeptides capable of binding KDR or VEGF/KDR complex with high affinity (e.g., having a K<1 μM), and dimer and multimeric constructs comprising these polypeptides. 1198-. (canceled)200. The agent of claim 199 , wherein the detectable label is conjugated to a dimeric or multimeric compound comprising two or more polypeptides having the ability to bind KDR or VEGF/KDR complex.202. The agent of claim 199 , wherein at least one of the polypeptides comprises an amino acid substitution claim 199 , an amide bond substitution claim 199 , a D-amino acid substitution claim 199 , a glycosylated amino acid claim 199 , a disulfide mimetic substitution claim 199 , an amino acid translocation claim 199 , a retro-inverso peptide claim 199 , a peptoid claim 199 , a retro-inversopeptoid claim 199 , or a synthetic peptide and wherein the polypeptide maintains its ability to bind the receptor.203. The agent of claim 199 , wherein at least one of the polypeptides does not include the C terminal GGGK extension in its amino acid sequence.205. A diagnostic imaging agent comprising a detectable label conjugated to at least two polypeptides having the ability to bind to KDR or VEGF/KDR complex claim 199 , wherein the detectable label is conjugated claim 199 , optionally via a linker or spacer claim 199 , to a dimer selected from the group consisting of D1 claim 199 , D2 claim 199 , D3 claim 199 , D5 claim 199 , D6 claim 199 , D7 claim 199 , D8 claim 199 , D9 claim 199 , D17 claim 199 , D19 claim 199 , D20 claim 199 , D22 claim 199 , D23 claim 199 , D24 claim 199 , D25 claim 199 , D26 claim 199 , D27 claim 199 , D28 claim 199 , and D31 claim 199 , wherein J is the spacer or linker ...

Novel active noise control biosensor

Provided is a novel active noise control biosensor including a detection plate, a signal detection module and a control module. The signal detection module includes a signal superimposable transistor and a readout circuit. The signal superimposable transistor has a secondary input terminal and a primary input terminal. The detection plate inputs a detected primary signal to the primary input terminal, and the control module processes an output signal from the signal detection module by a signal processing system and generates and inputs a secondary signal to the secondary input terminal. The primary signal and the secondary signal received by the signal superimposable transistor are superimposed to realize active noise control, and the superimposed signal is read out by the readout circuit and output as an input signal to the control module. The biosensor can achieve the detection of potential or charges and have active noise control characteristics.

ACCOUNT NUMBER REGISTRATION METHOD, APPARATUS, AND SYSTEM

An account number registration method is provided. Indication information transmitted by a transaction server is received, the indication information including a second business account number of a terminal, a second account name corresponding to the second business account number, and a second recipient account number, a resource being transferred out from the second business account number to the second recipient account number. A registered account number is allocated according to a first account name in response to the second business account number being the same as a first business account number that is pre-stored, the second account name being the same as the first account name that is pre-stored, and the second recipient account number being the same as a first recipient account number that is pre-stored. A notification message indicating a registration success is transmitted to the terminal. 1. An account number registration method , comprising:receiving, by at least one processor of a registration server, indication information transmitted by a transaction server, the indication information comprising a second business account number of a terminal, a second account name corresponding to the second business account number, and a second recipient account number, a resource being transferred out from the second business account number to the second recipient account number;allocating, by the at least one processor of the registration server, a registered account number according to a first account name in response to the second business account number being the same as a first business account number that is pre-stored, the second account name being the same as the first account name that is pre-stored, and the second recipient account number being the same as a first recipient account number that is pre-stored; andtransmitting, by the at least one processor of the registration server, a notification message indicating a registration success to the terminal. ...

PHOSPHODIESTERASE INHIBITORS AND USES THEREOF

The invention provides for compounds that are phosphodiesterase inhibitors. The invention further provides for a method for screening compounds that bind to and modulate a phosphosdiesterase protein. The invention also provides methods for treating conditions associated with accumulated amyloid-beta peptide deposit accumulations by administering a phosphodiesterase-binding compound to a subject. 2. The method of claim 1 , wherein the effective amount is at least about 1 mg/kg body weight claim 1 , at least about 2 mg/kg body weight claim 1 , at least about 3 mg/kg body weight claim 1 , at least about 4 mg/kg body weight claim 1 , at least about 5 mg/kg body weight claim 1 , at least about 6 mg/kg body weight claim 1 , at least about 7 mg/kg body weight claim 1 , at least about 8 mg/kg body weight claim 1 , at least about 9 mg/kg body weight claim 1 , or at least about 10 mg/kg body weight.3. The method of claim 1 , wherein A is N.4. The method of claim 1 , wherein Ris hydrogen.5. The method of claim 1 , wherein Ris —OCH.7. The method of claim 6 , wherein Ris CH.9. The method of claim 1 , wherein Ris CH—OH.10. The method of claim 1 , wherein Ris H.11. The method of claim 1 , wherein Ris a halogen.12. The method of claim 1 , wherein Ris chlorine.13. The method of claim 1 , wherein Ris —CN.14. The method of claim 1 , wherein Ris a halogen.15. The method of claim 1 , wherein Ris fluorine.17. The method of claim 1 , wherein Ris hydrogen.18. The method of claim 1 , wherein Ris C-Ccycloalkyl claim 1 , —NRR claim 1 , or —SR.19. The method of claim 1 , wherein Ris C-Ccycloalkyl or —NRR.20. The method of claim 1 , wherein Ris —NRR.21. The method of claim 1 , wherein Ris —NRR claim 1 , and wherein Rand Rare each independently hydrogen claim 1 , —C-Calkyl claim 1 , —C-Ccycloalkyl claim 1 , or —C(O)R claim 1 , wherein the C-Calkyl or C-Ccycloalkyl are optionally substituted with —C-Calkyl claim 1 , —C-Ccycloalkyl claim 1 , or —NRR; or claim 1 , Rand Rtogether with the nitrogen ...

Method of semi-solid indirect squeeze casting for magnesium-based composite material

The present invention relates to a method of semi-solid indirect squeeze casting for Mg-based composite material, which aims at improving the mechanical property of the cast by adding magnesium zinc yttrium quasicrystal of high hardness, high elastic modulus and excellent matrix binding property acting as the reinforcement into the magnesium alloy matrix and manufacturing the cast through smelting using a vacuum atmosphere smelting furnace, agitating with ultrasonic wave assisted vibration in the rotating impeller jet agitation furnace and indirect squeeze casting against the problem of poor wettability, easy agglomeration, inhomogeneous distribution between the reinforcement particles and the matrix materials and poor properties of the manufactured cast. The manufacturing method of the present invention has advanced technologies and detailed and accurate data. The cast has excellent microstructure compactness, no shrinkage cavities and shrinkage defects and the primary phase in the metallographic structure consists of spherical and near-spherical crystalline grains, wherein dendritic crystalline grains almost disappear and the size of the crystalline grain is obviously refined. The tensile strength of the Mg-based composite material cast reaches to 225 Mpa, the elongation rate thereof reaches to 6.5% and the hardness thereof reaches to 86 HV. So the manufacturing method of the present invention is an advanced semi-solid indirect squeeze casting method for the Mg-based composite material.

Compositions And Methods For Killing Insect And Non-Insect Pests

wherein R1 is CH3, C2H5, C3H7; saturated or unsaturated, straight or branched, or halogen substituted alkyl; and wherein R2 are independently H, halogen, nitrogen, oxygen, sulfur, saturated or unsaturated, straight or branched alkyl, alkenyl, alkyl halide, aldehyde, ketone, ether, ester, amine, or amide; optionally methyl benzoate, optionally a surfactant, and optionally a carrier. Also disclosed are methods for killing insects, involving treating an object or area with an insect killing effective amount of the compositions, optionally methyl benzoate, optionally a surfactant, and optionally a carrier.

DATA PROCESSING METHOD, APPARATUS, DEVICE AND STORAGE MEDIUM BASED ON UNMANNED VEHICLE

Provided are a data processing method, apparatus, device and storage medium based on an unmanned vehicle, the method includes: acquiring data generated in an unmanned vehicle operating environment of the unmanned vehicle and type information of the unmanned vehicle operating environment; acquiring a data transformation logic corresponding to the type information from a pre-stored adaption repository, which stores data transformation logics corresponding to different type information; and transforming a data structure of the data according to the data transformation logic corresponding to the type information to obtain data in compliance with a preset data structure. By transforming data generated in different unmanned vehicle operating environments into data in compliance with the preset data structure, the cloud server can be assisted in analyzing and consistently processing the data in compliance with the preset data structure after they have been transmitted to the cloud server, thus improving the data processing efficiency. 1. A data processing method based on an unmanned vehicle , which is applicable in the unmanned vehicle , the method comprising:acquiring data generated in an unmanned vehicle operating environment of the unmanned vehicle and type information of the unmanned vehicle operating environment;acquiring a data transformation logic corresponding to the type information from a pre-stored adaption repository, wherein the adaption repository stores data transformation logics corresponding to different type information; andtransforming a data structure of the data according to the data transformation logic corresponding to the type information to obtain data in compliance with a preset data structure.2. The method according to claim 1 , wherein after the transforming a data structure of the data according to the data transformation logic corresponding to the type information to obtain data in compliance with a preset data structure claim 1 , the method ...

COMPOUND AND USE THEREOF IN SYNTHESIS OF BRIVARACETAM INTERMEDIATE AND CRUDE DRUG

The present application provides a compound in formula III, and further provides a use of the compound in the synthesis of a Brivaracetam intermediate and a crude drug, and a synthesis method. A raw material involved in the method of the present application is low in costs and easily available; (R)-4-propyl-dihydrofuran-2-ketone having high optical purity can be prepared; complicated separation and purification steps are avoided; costs are reduced, and the method is more applicable to industrial production. 24-. (canceled)68-. (canceled)1011-. (canceled)12. The method according to claim 9 , when the method comprises preparation of the compound of formula II from the compound of formula I claim 9 , the method comprises the following steps:reacting the compound of the formula I with R-epichlorohydrin in a solvent under the action of a base (a), followed by treatment with an acid or a base (b) to prepare the compound of the formula II.13. The method according to claim 12 , wherein the base (a) is selected from one or more of sodium methoxide claim 12 , potassium methoxide claim 12 , magnesium methoxide claim 12 , sodium ethoxide claim 12 , potassium ethoxide claim 12 , sodium t-butoxide claim 12 , potassium t-butoxide claim 12 , sodium hydroxide claim 12 , potassium hydroxide claim 12 , potassium carbonate claim 12 , sodium carbonate or cesium carbonate; the acid is selected from one or more of acetic acid claim 12 , propionic acid claim 12 , citric acid claim 12 , hydrochloric acid claim 12 , sulfuric acid claim 12 , phosphoric acid claim 12 , nitric acid claim 12 , methanesulfonic acid claim 12 , benzenesulfonic acid or p-toluenesulfonic acid; the base (b) is selected from one or more of sodium hydroxide claim 12 , potassium hydroxide claim 12 , potassium carbonate or sodium carbonate.1416-. (canceled)17. The method according to claim 12 , wherein the solvent is selected from one or more of water claim 12 , methanol claim 12 , ethanol claim 12 , propanol claim 12 , ...

Curable resin composition

A polymer resin composition free of solvent and adapted for in situ curing including: (a) at least one epoxy resin compound; (b) at least one isocyanate compound; and (c) a catalyst system including a combination of at least one primary catalyst and at least one secondary catalyst; wherein the primary catalyst includes (ci) at least one organoantimony catalyst; and wherein the secondary catalyst includes (cii) a nitrogen-containing catalyst; and a process for preparing the above composition.

ANTIBODIES AGAINST OX40 AND USES THEREOF

Provided herein are antibodies, or antigen binding portions thereof, that bind to OX40. Also provided are uses of these proteins in therapeutic applications, such as in the treatment of cancer. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain variable region of the antibodies, and vectors comprising the polynucleotides encoding the heavy and/or light chain variable region of the antibodies. 12-. (canceled)3. An isolated monoclonal antibody which binds to OX40 , comprising:(a) heavy chain CDR1, CDR2, and CDR3 sequences comprising SEQ ID NOs: 87, 317, and 89, respectively, and light chain CDR1, CDR2, and CDR3 sequences comprising SEQ ID NOs: 90-92, respectively;(b) heavy chain CDR1, CDR2, and CDR3 sequences comprising SEQ ID NOs: 11-13, respectively, and light chain CDR1, CDR2, and CDR3 sequences comprising SEQ ID NOs: 14-16, respectively;(c) heavy chain CDR1, CDR2, and CDR3 sequences comprising SEQ ID NOs: 19-21, respectively, and light chain CDR1, CDR2, and CDR3 sequences comprising SEQ ID NOs: 22-24, respectively;(d) heavy chain CDR1, CDR2, and CDR3 sequences comprising SEQ ID NOs: 19-21, respectively, and light chain CDR1, CDR2, and CDR3 sequences comprising SEQ ID NOs: 25-27, respectively;(e) heavy chain CDR1, CDR2, and CDR3 sequences comprising SEQ ID NOs: 31-33, respectively, and light chain CDR1, CDR2, and CDR3 sequences comprising SEQ ID NOs: 34-36, respectively;(f) heavy chain CDR1, CDR2, and CDR3 sequences comprising SEQ ID NOs: 39-41, respectively, and light chain CDR1, CDR2, and CDR3 sequences comprising SEQ ID NOs: 42-44, respectively;(g) heavy chain CDR1, CDR2, and CDR3 sequences comprising SEQ ID NOs: 39-41, respectively, and light chain CDR1, CDR2, and CDR3 sequences comprising SEQ ID NOs: 45-47, respectively;(h) heavy chain CDR1, CDR2, and CDR3 sequences comprising SEQ ID NOs: 51-53, respectively, and light chain CDR1, CDR2, and CDR3 sequences comprising SEQ ID NOs: 54-56, respectively;(i) ...

DETECTION DEVICE BASED ON SHADOW IMAGING OF PLATELETS, AND METHOD THEREOF

The present invention provides a detection device based on the shadow imaging of platelets and a method thereof. The method comprises following steps: optically projecting and/or photographing a blood sample to be detected directly by an image sensor chip having a submicron pixel size and a megapixel scale, the blood sample being injected into a sample chamber of a microfluidic chip fixed to the surface of the image sensor chip; and then, identifying and counting imaging results by an image processing algorithm when the physical pixel size, in the imaging results, occupied by abnormally-sized platelets in the blood sample is significantly greater than the physical pixel size occupied by normally-sized platelets, so as to obtain the number and proportion of the abnormally-sized platelets. The present invention compensates for the defects of existing optical lens-based microscopic detection, provides a large field of view while satisfying the needs for resolution, greatly improves the detection efficiency, can realize the statistically significant microscopic observation, and provides early warning and diagnostic reference for the occurrence of clinical diseases such as stroke. 1. A detection device based on the shadow imaging of platelets , characterized in that the device comprises a shadow imaging device , an LED light source , a chip control system , a data storage and processing system and a data display system; the shadow imaging device comprises an image sensor chip and a microfluidic chip; the image sensor chip has a megapixel scale and a submicron pixel size; the microfluidic chip is fixed to the surface of the image sensor chip; the surface of the image sensor chip serves as a substrate of the microfluidic chip; a cavity on the microfluidic chip and the surface of the image sensor chip form a sample chamber; the LED light source is arranged directly above the shadow imaging device , and a light emitting surface of the LED light source is located on an ...

HISTONE ACETYLTRANSFERASE MODULATORS AND USES THEREOF

The invention provides compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels and/or accumulations of alpha-synuclein as well as cancer by administering a compound hat modulates HAT to a subject. 2. The method of claim 1 , wherein the effective amount is at least about 1 mg/kg body weight claim 1 , at least about 2 mg/kg body weight claim 1 , at least about 3 mg/kg body weight claim 1 , at least about 4 mg/kg body weight claim 1 , at least about 5 mg/kg body weight claim 1 , at least about 6 mg/kg body weight claim 1 , at least about 7 mg/kg body weight claim 1 , at least about 8 mg/kg body weight claim 1 , at least about 9 mg/kg body weight claim 1 , at least about 10 mg/kg body weight claim 1 , at least about 15 mg/kg body weight claim 1 , at least about 20 mg/kg body weight claim 1 , at least about 25 mg/kg body weight claim 1 , at least about 30 mg/kg body weight claim 1 , at least about 40 mg/kg body weight claim 1 , at least about 50 mg/kg body weight claim 1 , at least about 75 mg/kg body weight claim 1 , or at least about 100 mg/kg body weight.3. The method of claim 1 , wherein the cancer comprises B cell lymphoma claim 1 , colon cancer claim 1 , lung cancer claim 1 , renal cancer claim 1 , bladder cancer claim 1 , T cell lymphoma claim 1 , myeloma claim 1 , leukemia claim 1 , chronic myeloid leukemia claim 1 , acute myeloid leukemia claim 1 , chronic lymphocytic leukemia claim 1 , acute lymphocytic leukemia claim 1 , hematopoietic neoplasias claim 1 , thymoma claim 1 , lymphoma claim 1 , sarcoma claim 1 , lung cancer claim 1 , liver cancer claim 1 , non-Hodgkins lymphoma claim 1 , Hodgkins lymphoma claim 1 , uterine cancer claim 1 , renal cell carcinoma claim 1 , hepatoma claim 1 , adenocarcinoma claim 1 , breast cancer claim 1 , pancreatic cancer ...

DIFFUSION BASED EX-SITU GROUP V (P, As, Sb, Bi) DOPING IN POLYCRYSTALLINE CdTe THIN FILM SOLAR CELLS

Described herein is a diffusion-based ex-situ group V element doping method in the CdCl2 heat-treated polycrystalline CdTe film. The ex-situ doping using group V halides, such as PCl3, AsCl3, SbCl3, or BiCl3, demonstrated a promising PCE of ˜18% and long-term light soaking stability in CdSe/CdTe and CdS/CdTe devices with decent carrier concentration>1015 cm−3. This ex-situ solution or vapor process can provide a low-cost alternative pathway for effective doping of As, as well as P, Sb, and Bi, in CdTe solar cells with limited deviation from the current CdTe manufacturing process.

A CURABLE EPOXY RESIN COMPOSITION

A curable epoxy resin composition, upon curing, has a clarity value of at least 30% and provides improved impact strength while maintaining glass transition temperature; and a process of preparing the curable epoxy resin composition. 2. The curable epoxy resin composition of claim 1 , wherein the curing agent is selected from an anhydride compound claim 1 , a polyoxyalkylene polyamine claim 1 , a cycloaliphatic polyamine claim 1 , or mixtures thereof.3. The curable epoxy resin composition of claim 1 , wherein the curing agent is selected from a polyoxypropylenediamine claim 1 , isophorondiamine; 1 claim 1 ,3-cyclohexanebis(methylamine); 4 claim 1 ,4′-methylenebis (cyclohexylamine); 1 claim 1 ,2-diaminocyclohexane; 4 claim 1 ,4′-dianinodicyclohexylmethane; or mixtures thereof.4. The curable epoxy resin composition of claim 1 , wherein the curing agent is selected from nadic maleic anhydride; methyltetrahydrophthalic anhydride; methylhexahydrophthalic anhydride; methyl-(endo)-5-norbornene-2 claim 1 ,3-dicarboxylic anhydride; hexahydrophthalic anhydride; tetrahydrophthalic anhydride; pyromellitic dianhydride; ciscyclopentanetetracarboxylic acid dianhydride; hemimellitic anhydride; trimellitic anhydride; naphthalene-1 claim 1 ,8-dicarboxylic acid anhydride; phthalic anhydride; dichloromaleic anhydride; dodecenylsuccinic anhydride; glutaric anhydride; maleic anhydride; succinic anhydride; or mixtures thereof.5. The curable epoxy resin composition of claim 1 , further comprising a curing catalyst.6. The curable epoxy resin composition of claim 5 , wherein the curing catalyst is present in an amount of from 0.1 to 1 wt % claim 5 , based on the total weight of the epoxy resin composition.7. The curable epoxy resin composition of claim 1 , wherein the at least one anhydride-reactive group of the amphiphilic block copolymer comprises at least one hydroxyl functional group.8. The curable epoxy resin composition of claim 1 , wherein the epoxy resin miscible block segment ...

Methods of Attracting Drosophila Suzukii Using Acetoin Blend

Methods of attracting involving treating an object or area with a attracting effective amount of a composition containing acetoin and at least one compound selected from ethyl octanoate, acetic acid, ethyl acetate, phenethyl alcohol, or mixtures thereof; wherein said composition does not contain ethanol. 1Drosophila suzukii,Drosophila suzukii. A method of attracting said method comprising treating an object or area with a attracting effective amount of a composition consisting of acetoin , ethyl octanoate , acetic acid , ethyl acetate , and phenethyl alcohol in a ratio of 1:1:15:5:1 , optionally a carrier , optionally a biological control agent , and optionally an insecticide.2. (canceled)3. (cancelled)4. (canceled)5. (canceled)6. (canceled)7Drosophila suzukii,Drosophila suzukii. A method of attracting said method consisting of treating an object or area with a attracting effective amount of a composition consisting of acetoin , ethyl octanoate , acetic acid , ethyl acetate , and phenethyl alcohol in a ratio of 1:1:15:5:1 , optionally a carrier , optionally a biological control agent , and optionally an insecticide. This application claims the benefit of U.S. Provisional Application No. 62/304,497 filed 7 Mar. 2016, which is incorporated herein by reference in its entirety.Disclosed are methods of attracting involving treating an object or area with a attracting effective amount of a composition containing acetoin and at least one compound selected from ethyl octanoate, acetic acid, ethyl acetate, phenethyl alcohol, or mixtures thereof; wherein said composition does not contain ethanol.The spotted wing drosophila (SWD), Matsumura (Diptera: Drosophilidae), is an invasive fruit-infesting fly native to Southeast Asia (Calabria, G., et al., J. Appl. Entomol., 136: 139-147 (2010)). Since it was accidently introduced to the United States in August in California in 2008, has rapidly spread across the United States and has been detected in a total of 41 states from CA to ME ...

ESTER RESINS

A vinyl ester resin composition comprising a reaction product of: (a) a polyepoxide resin; (b) an unsaturated carboxylic acid; and (c) a reactive carboxyl group terminated amphiphilic block copolymer, a reactive epoxy group terminated amphiphilic block copolymer, or a mixture thereof; and a cured thermoset composite product produced from the above vinyl ester resin composition. 1. A vinyl ester resin formulation comprising a blend of:(a) at least one vinyl ester resin; and(b) a reactive carboxyl group terminated amphiphilic block copolymer, a reactive epoxy group terminated amphiphilic block copolymer, or a mixture thereof.2. A vinyl ester resin composite product comprising a reaction product of the following reaction mixture:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, '(a) the resin blend of ; and'}(b) a catalyst.3. The vinyl ester resin composite of claim 2 , wherein the reaction product mixture includes further another vinyl ester resin different from the vinyl ester resin of component (a).4. The vinyl ester resin composite of claim 2 , wherein the reaction product mixture includes further a copolymerizable reactive monomer.5. (canceled)6. (canceled)7. (canceled)8. A vinyl ester resin composition comprising a reaction product of the following reaction mixture:(a) a polyepoxide resin;(b) an unsaturated carboxylic acid; and(c) a reactive carboxyl group terminated amphiphilic block copolymer, a reactive epoxy group terminated amphiphilic block copolymer, or a mixture thereof; wherein an epoxy vinyl ester resin or an unsaturated polyester resin is formed; and wherein the reactive carboxyl group terminated amphiphilic block copolymer, the reactive epoxy group terminated amphiphilic block copolymer, or a mixture thereof is reacted into the backbone of the epoxy vinyl ester resin or an unsaturated polyester resin.9. The composition of claim 8 , wherein the polyepoxide resin is bisphenol A diglycidyl ether claim 8 , tetrabromobisphenol A diglycidyl ether claim 8 , ...

METHOD FOR TREATMENT OF RESPIRATORY INFECTIONS AND CANCERS OF THE RESPIRATORY SYSTEM USING COLD ATMOSPHERIC PLASMA

A method for performing cold atmospheric plasma treatment of respiratory infections or lung cancer having a source of a carrier gas, a cold atmospheric plasma generator connected to the source of carrier gas, a source of compressed air, a humidifier connected to the source of compressed air, a source of oxygen, a ventilator having inputs connected to an output of the humidifier and the source of oxygen, a mixer having an interior chamber formed from a dielectric, an active electrode inside the interior chamber, and an outer electrode connected to ground, wherein the mixer has a fluid input port connected to a gas output of the cold atmospheric plasma generator and an output of the ventilator, and a delivery member connected to an output of the mixer for delivering combined humidified air and cold atmospheric plasma to a respiratory system of a patient. 1. A method for performing plasma treatment of respiratory infections comprising:humidifying a carrier gas flowing from a source of a carrier gas;humidifying a feed gas flowing from a source of a feed gas;supplying said humidified carrier gas to a mixing chamber formed from a dielectric, wherein an active electrode inside said mixing chamber is connected to an electrical output of a plasma generator, and a return electrode outside said mixing chamber is connected to a ground;supplying said humidified feed gas to said mixing chamber;providing electrical energy from said plasma generator to said active electrode to plasmatized said carrier gas in said mixing chamber to generate reactive species;delivering said generated reactive species generated in said mixing chamber through a fluid delivery member connected to an output of said mixer to a patient.2. A method for performing plasma treatment of respiratory infections according to claim 1 , wherein said carrier gas comprises at least one of helium claim 1 , argon claim 1 , nitrogen and oxygen.3. A method for performing plasma treatment of respiratory infections ...

SYSTEM FOR TREATMENT OF RESPIRATORY INFECTIONS AND CANCERS OF THE RESPIRATORY SYSTEM USING COLD ATMOSPHERIC PLASMA

A system for performing cold atmospheric plasma treatment of respiratory infections or lung cancer having a source of a carrier gas, a cold atmospheric plasma generator connected to the source of carrier gas, a source of compressed air, a humidifier connected to the source of compressed air, a source of oxygen, a ventilator having inputs connected to an output of the humidifier and the source of oxygen, a mixer having an interior chamber formed from a dielectric, an active electrode inside the interior chamber, and an outer electrode connected to ground, wherein the mixer has a fluid input port connected to a gas output of the cold atmospheric plasma generator and an output of the ventilator, and a delivery member connected to an output of the mixer for delivering combined humidified air and cold atmospheric plasma to a respiratory system of a patient. 1. A system for performing plasma treatment of respiratory infections comprising:a source of a carrier gas;a humidifier connected to said source of a carrier gas;a source of a feed gas;a humidifier connected to said source of a feed gas;a plasma generator configured to plasmatize said carrier gas into a plasma;a mixer having an interior chamber formed from a dielectric, an active electrode inside said interior chamber and connected to an electrical output of said plasma generator, and an outer electrode connected to a ground, wherein said mixer has a first fluid input port connected to said source of a carrier gas and a second fluid input connected to said source of a feed gas; anda fluid delivery member connected to an output of said mixer for delivering reactive species generated in said mixer to a patient.2. A system for performing plasma treatment of respiratory infections according to claim 1 , wherein said carrier gas comprises at least one of helium claim 1 , argon claim 1 , nitrogen and oxygen.3. A system for performing plasma treatment of respiratory infections according to claim 1 , wherein said delivery ...

PATH DETECTION SYSTEM BASED ON SOLAR BLIND ULTRAVIOLET LIGHT SIGNALS

A path detection system based on SBUV light signals is provided, including a SBUV light signal emitter, a SBUV detectors and a signal processing module, wherein the SBUV light signal emitter is arranged on a road to serve as a path mark line; the SBUV detector is configured to detect the path mark line and transmit the detected signals from the SBUV light signal emitter to the signal processing module; and the signal processing module acquires a traveling path in real time by using a path line extraction algorithm, and eventually outputs path information. 1. A path detection system based on solar blind ultraviolet light signals , comprising a SBUV light signal emitter , a SBUV detector and a signal processing module , wherein the SBUV light signal emitter is arranged on a road to serve as a path mark line; the SBUV detector is configured to detect the path mark line and transmit the detected signals from the SBUV light signal emitter to the signal processing module; and the signal processing module acquires a travelling path in real time by using a path line extraction algorithm , and outputs path information.2. The path detection system based on SBUV light signals according to claim 1 , wherein the SBUV light signal emitter can irradiate SBUV light signals at different intensities claim 1 , and SBUV light signal generated by a plurality of SBUV light signal emitters for marking a path have a same intensity or different intensities.[U4]3. The path detection system based on SBUV light signals according to claim 2 , wherein the SBUV light signal emitter comprises a power supply claim 2 , SBUV light sources and a signal intensity control circuit; and claim 2 , when in use claim 2 , the intensities of all the SBUV light sources are kept consistent.4. The path detection system based on SBUV light signals according to claim 1 , wherein the SBUV light signal emitter as a path mark line can mark a road center line claim 1 , a road edge line claim 1 , or a line partition ...

PHOTOSENSITIVE DETECTOR, IMAGING SENSOR CHIP FORMED USING THE PHOTOSENTIVE DETECTOR, AND DETECTION METHOD

A photosensitive detector includes an array of detectin units, each detection unit having a light-sensing transistor (), a charge storage transistor () and a reading transistor (), or comprising a light-sensing transistor, a charge transfer transistor (), a charge storage transistor and a reading transistor. The light-sensing transistor is configured to realize the light-sensing function of the photosensitive detector; the charge storage transistor is configured to store photogenerated charges; the reading transistor is configured to read a signal; and, the charge transfer transistor is configured to control the transfer of the photogenerated charges. The photosensitive detector can realize global shutter and fast reading, and is compatible with the existing floating gate CMOS process, and the failure of any pixel will not affect the normal operation of the whole imaging array. 1. A global-shutter photosensitive detector based on a composite dielectric gate MOSFET , comprising an array formed of multiple detection units , characterized in that each detection unit comprises a light-sensing transistor , a charge storage transistor and a reading transistor , all of which are stacked above a same P-type semiconductor substrate;the light-sensing transistor is configured to realize the light-sensing function of the photosensitive detector, having a bottom insulating dielectric layer, a charge coupled layer, a top insulating dielectric layer and a control gate stacked above the P-type semiconductor substrate successively from the bottom up, or, a bottom insulating dielectric layer and a control gate stacked above the P-type semiconductor substrate successively from the bottom up;the charge storage transistor is configured to store photogenerated charges, having a bottom insulating dielectric layer, a charge coupled layer, a top insulating dielectric layer and a control gate stacked above the P-type semiconductor substrate successively from the bottom up;the reading ...

MONITORING CONVERSIONS AND FEE DETERMINATION OF ONLINE ADVERTISEMENTS USING A SOCIAL NETWORKING SYSTEM

When the social networking system selects an advertisement for presentation to the user by a client device, a content identifier associated with the selected advertisement is stored in an advertisement history associated with the user. When the user performs a conversion event associated with the selected advertisement, the social networking system receives a content identifier and a user identifier from a client device used that performed the conversion event and retrieves the user's advertisement history. If the retrieved advertisement history includes a content identifier for the selected advertisement matching the content identifier received from the client device and a time between the conversion event and providing the selected advertisement to the client device is less than a threshold time period, a fee is determined for presentation of the selected advertisement. 1. A method comprising:accessing an advertisement history associated with a user identifier of a user of a social networking system, the ad history identifying advertisements presented to the user;selecting an ad for presentation to a client device of the user;storing a content identifier (ID) associated with the selected ad in the ad history associated with the user identifier of the user;receiving user identifying information associated with the user identifier of the user and a content ID from an additional client device after a conversion event has occurred using the additional client device;retrieving the advertisement history associated with the received user identifying information;the received content ID with the content ID associated with the selected ad stored in the ad history;determining that the ad caused the conversion event based at least in part on a time between the conversion event and providing the selected ad to the client device; anddetermining a fee for presentation of the selected ad to the user, the fee determined based on the determination that the ad caused the conversion ...