Apparatus and Method for Determining the Thermal Stability of Fluids

A thermal oxidation tester is shown for determining thermal stability of a fluid, particularly hydrocarbons when subjected to elevated temperatures. The tendency of the heated fluid to oxidize and (1) form deposits on a surface of a heater tube and (2) form solids therein, are both measured at a given flow rate, temperature and time. The measured results are used to determine whether a fluid sample passes or fails the test. Results of measurements are recorded in a memory device on one end of the heater tube on which the deposits were made. 1. An apparatus for testing thermal oxidation stability of a test sample such as a hydrocarbon fuel comprising:a source of electric power;an intelligent heater tube connected to said source of electric power for flowing current to heat a center section of said intelligent heater tube to a predetermined temperature;a coolant flow circuit supplying coolant to each end of said intelligent heater tube to keep each end thereof near room temperature;an aeration circuit with an aeration pump for pumping air to aerate said test simple in a sample container;a test sample flow circuit for flowing said test sample around said center section to heat said test sample to said predetermined temperature, sample drive pump pumping said test sample from said sample container around said center section of said intelligent heater tube;', 'a differential pressure filter in said test sample flow circuit after said intelligent heater tube to filter out any solids that may have formed in said test sample when heated to said predetermined temperature due to oxidation of said test sample;', 'a differential pressure sensor for measuring differential pressure across said differential pressure filter;', 'a back pressure regulator for maintaining said test sample being pumped by said sample drive pump at a test pressure high enough to keep said test sample in a liquid phase when heated to said predetermined temperature;', 'waste container for collecting such ...

Drop Counter And Flow Meter For Apparatus And Method For Determining The Thermal Stability Of Fluids

A thermal oxidation tester is shown for determining thermal stability of a fluid, particularly hydrocarbons when subjected to elevated temperatures. The tendency of the heated fluid to oxidize and (1) form deposits on a surface of a heater tube and (2) form solids therein, are both measured at a given flow rate, temperature and time. The measured results are used to determine whether a fluid sample passes or fails the test. Sample flow rate is important in the jet fuel thermal oxidation test. Current practice requires manual drop counting or flow confirmation with the use of volumetric glassware. An apparatus is described to precisely measure the flow rate and automatically perform flow rate check using a drip rate method and/or volumetric method.

Zinc Oxide Nanostructures and Sensors Using Zinc Oxide Nanostructures

A method for preparing zinc oxide nanostructures using arc discharge is disclosed. The method comprises the provision of an anode and a cathode in an arc discharge chamber. Current is supplied to the anode and the cathode to establish an arc discharge between the cathode and the anode to vaporise the anode and produce zinc oxide nanostructures. Contemplated is the use of the zinc oxide nanostructures to produce components that have applications in, for example, optoelectronics, energy storage devices, field emission devices, and sensors such as UV photosensors, gas sensors and humidity sensors. Disclosed is a gas sensor and method for its production, where said method comprises the provision of a sensor substrate comprising a conducting thin film at least partially covering at least two regions on at least one surface of a sensor substrate material to define a gap in the conducting thin film, the application of a mixture of zinc oxide nanostructures and a non-ionic polymer to at least a portion of the gap i the conducting thin film to thereby bridge the gap. Optionally contemplated is a step of annealing the mixture of zinc oxide nanostructures and non-ionic polymer applied to said sensor substrate to produce the sensor component. 1. A method for producing zinc oxide nanostructures , the method comprising:providing an anode and a cathode in an arc discharge chamber, wherein the cathode is arranged horizontally in the arc discharge chamber and the anode is arranged vertically;supplying current to the anode and the cathode to establish an arc discharge between the cathode and the anode to vaporise the anode and produce the zinc oxide nanostructures;terminating the current supply to the anode and the cathode; andcollecting the resulting zinc oxide nanostructures.2. A method as claimed in claim 1 , wherein the anode is a high purity zinc anode.3. A method as claimed in claim 2 , wherein the zinc anode is at least 99.0% pure claim 2 , at least 99.9% pure claim 2 , at ...

Technology for the Preparation of Microparticles

Microspheres are produced by contacting a solution of a macromolecule or small molecule in a solvent with an antisolvent and a counterion, and chilling the solution. The microspheres are useful for preparing pharmaceuticals, nutraceuticals, cosmetic products and the like of defined dimensions. 1. A method of making microparticles of a compound , comprising:a) adding a counterion to a solution containing the compound in a solvent;b) adding an antisolvent to the solution; andc) gradually cooling the solution to a temperature below about 25° C., whereby a composition containing microparticles comprising the compound is formed, wherein steps a), b) and c) are performed simultaneously, sequentially, intermittently, or in any order.2. The method of claim 1 , wherein the counterion is not a polymer.3. The method of claim 1 , wherein the antisolvent is not a polymer.4. The method of claim 1 , wherein prior to step a) claim 1 , the compound is dissolved in the solvent at a temperature of about or at 30° C. or below.5. The method of claim 4 , wherein prior to step a) claim 4 , the compound is dissolved in the solvent at a temperature of about or at 25° C. or below.6. The method of claim 1 , wherein steps a) and b) are performed at ambient temperature.7. The method of claim 1 , wherein none of the solutions of steps a)-c) are heated and/or maintained at a temperature above about or at 30° C.8. The method of claim 1 , wherein the compound is not a protein or a polypeptide.9. The method of claim 1 , wherein steps a) and b) are performed simultaneously claim 1 , sequentially claim 1 , intermittently claim 1 , or in any order claim 1 , followed by step c).10. The method of claim 1 , wherein steps b) and c) are performed simultaneously claim 1 , sequentially claim 1 , intermittently claim 1 , or in any order claim 1 , preceded by step a).11. The method of claim 1 , wherein steps a) and c) are performed simultaneously.12. The method of claim 1 , wherein the counterion and the ...

House Architectural Complex Wind-concentrating Type And An Open-field Structure Group Wind-concentrating Type Wind Power Hub Generating Station/Power Station

A house architectural complex and open-field structure wind-concentrating type wind power hub generating station or power station are provided, which use the relation that the power of a wind driven generator is proportional to the third power of the wind speed, and use the wind-concentrating structure of our invention and transmission mode principle thereof so as to increase the speed of the natural wind about 3˜8 m/sec with probability above 80% to 50˜70 m/sec, then the power of a unit area of the blade will be increased by about 100˜340 times; a high architectural complex with an area of 60,000 mcan provide a wind generation set with the installed capacity of 20,000˜50,000 kw if the wind speed thereof is 50 m/sec after collecting wind, and the installed capacity of an open-field structure wind power hub power station can reach 50,000˜150,000 kw and a wind driven power station with corresponding powers when the wind speed is set as 70 m/sec. 128288728228128282232822212120219282829131428312829131428628. A house architectural complex (Hereinafter refers to as the architectural complex) wind-concentrating type and an open-field structure group (Hereinafter refers to as the structure group) wind-concentrating type wind power hub generating station/power station , wherein: the central part , of the architectural complex or the structure group is provided with a high-floor , super high-floor hollow cylindrical central tower () which runs through the height of the whole floors; each floor of the tower () comprises a hollow cylinder with inner diameter of D and a impeller housing () formed by the upper and lower floorboards () perpendicular to the cylinder; the center point O of the central tower () is provided with a concentrated drive shaft assembly () which runs through the height of the whole tower () , is perpendicular to and coaxial with the ground central axis () and runs through each floor of the tower (); in this way the wind torque of the impeller in each floor ...

High Efficient and High Power Plane Centric Gear Unit

A plane centric gear unit has a circumferentially floating ring gear . Both ends of the ring gear are respectively fixed with cloth boards equipped with hollow shaft sleeves ; the reaction forces of the ring gear and external gear are equal and in opposite directions, and act on inner ring bearings of the hollow shaft sleeves on the same straight line; the outer ring bearings of the hollow shaft sleeves are unloaded, therefore the sum of the bearing reaction forces is reduced, the total transmission efficiency and power reaches above 97% and tens of thousands KW grade, the noises are lower, the gear surface contact pressure is about 1/10 of the external mesh pair, the gear surface contact life is increased by 1000 times than the external mesh pair, and the total weight is reduced by 2˜3 times. 113347454884105412625. A planet type gear unit , in particular a planocentric gear unit , wherein a circumferentially floating ring gear () is provided , both ends of the ring gear are respectively fixed with cloth boards (); every centers of the cloth boards () are respectively provided with hollow shaft sleeves () , bearings () installed in the inner rings of the hollow shaft sleeves () support the spindles in both ends of the eccentric wheel () , the outer rings of the hollow shaft sleeves () are installed with bearings () , the outer rings of the bearings () are fixed on a stationary part; the end face of one hollow shaft sleeve () is fixed with an output (input) shaft () , the spindle in one end of the eccentric wheel () passes through the end face of another hollow shaft sleeve (); the ring gear () meshes with one and more external gears () , the center part of each external gear is supported on a tumbler bearing (); when multiple external gears () are used , the circumferential included angles set by the eccentric wheel () axially are equal , therefore a planocentric gear unit is formed.23101. The planocentric gear unit according to claim 1 , wherein when the cloth ...

Methods, Compounds, and Compositions For Treatment and Prophylaxis in the Respiratory Tract

The present invention provides a method of reducing the quanitity of mucus in the respiratory tract of a subject with elevated levels of mucus in said respiratory tract. The method includes administering to the subject a compound or composition containing a therapeutically effective amount of a fusion protein comprising a sialidase or an active portion thereof and an anchoring domain. The therapeutically effective amount comprises an amount of the fusion protein that results in a reduction of the quanitity of mucus in the respiratory tract after administration of the compound or composition when compared to the quantity of mucus present prior to administration of the compound or composition.

MULTIMERIC PROTEINS AND METHODS OF MAKING AND USING SAME

The invention provides multimerization polypeptides capable of conferring formation of multimers when the multimerization polypeptide is linked to a molecule, such as a heterologous polypeptide sequence. 1112.-. (canceled)113. A multimerization polypeptide comprising an amino acid sequence selected from the group consisting of (i) SEQ ID NO: 159; and (ii) SEQ ID NO: 159 , wherein one or more of amino acid positions 1 , 4 , 8 , 11 , 15 , 18 , 22 , 25 , and 29 is substituted with leucine , isoleucine , or valine.114. The multimerization polypeptide of claim 113 , wherein the polypeptide comprises the amino acid sequence of SEQ ID NO: 159.115. The multimerization polypeptide of claim 114 , wherein the polypeptide comprises the amino acid sequence of SEQ ID NO: 159 claim 114 , wherein one or more of amino acid positions 1 claim 114 , 4 claim 114 , 8 claim 114 , 11 claim 114 , 15 claim 114 , 18 claim 114 , 22 claim 114 , 25 claim 114 , and 29 is substituted with leucine claim 114 , isoleucine claim 114 , or valine.116. The multimerization polypeptide of claim 114 , wherein the polypeptide consists of the amino acid sequence of SEQ ID NO: 159.117. The multimerization polypeptide of claim 115 , wherein the polypeptide consists of the amino acid sequence of SEQ ID NO: 159 claim 115 , wherein one or more of amino acid positions 1 claim 115 , 4 claim 115 , 8 claim 115 , 11 claim 115 , 15 claim 115 , 18 claim 115 , 22 claim 115 , 25 claim 115 , and 29 is substituted with leucine claim 115 , isoleucine claim 115 , or valine.118. A chimeric protein comprising a heterologous polypeptide fused to the N-terminus of the multimerization polypeptide of .119. The chimeric protein of claim 118 , wherein the heterologous polypeptide is selected from the group consisting of a binding protein claim 118 , enzyme claim 118 , receptor claim 118 , ligand claim 118 , nucleic acid binding protein claim 118 , growth regulatory factor claim 118 , differentiative factor claim 118 , and chemotactic ...

Novel Class of Therapeutic Protein Based Molecules

The present invention provides new compositions and methods for preventing and treating pathogen infection. In particular, the present invention provides compounds having an anchoring domain that anchors the compound to the surface of a target cell, and a therapeutic domain that can act extracellularly to prevent infection of a target cell by a pathogen, such as a virus. The present invention also comprises therapeutic compositions having sialidase activity, including protein-based compounds having sialidase catalytic domains. Compounds of the invention can be used for treating or preventing pathogen infection, and for treating and reducing allergic and inflammatory responses. The invention also provides compositions and methods for enhancing transduction of target cells by recombinant viruses. Such compositions and methods can be used in gene therapy. 1. A fusion protein , comprising at least one catalytic domain of a sialidase and at least one anchoring domain , wherein the catalytic domain sequence comprises:a) the sequence of amino acids extending from amino acid 274 to amino acid 681 of SEQ ID NO:12, inclusive and lacks the sequence that consists of the sequence extending from amino acid 1 to amino acid 273 and from amino acid 682 to amino acid 901 of SEQ ID NO:12;b) the sequence of amino acids extending from amino acid 290 to amino acid 666 of SEQ ID NO:12, inclusive and lacks the sequence that consists of the sequence extending from amino acid 1 to amino acid 289 and from amino acid 667 to amino acid 901 of SEQ ID NO:12; orc) the sequence of amino acids extending from amino acid 290 to amino acid 681 of SEQ ID NO:12, inclusive and lacks the sequence that consists of the sequence extending from amino acid 1 to amino acid 289 and from amino acid 682 to amino acid 901 of SEQ ID NO:12; and the anchoring domain comprises the GAG-binding domain of human platelet factor 4 (SEQ ID NO:2), the GAG-binding domain of human interleukin 8 (SEQ ID NO:3), the GAG-binding ...

DISPLAY TERMINAL AND METHOD FOR DISPLAYING INTERFACE WINDOWS

Display terminals and methods for displaying interface windows are provided. In an exemplary method, at least two interface window thumbnails can be obtained and stacked to display. A display instruction can then be received. According to the display instruction, the at least two interface window thumbnails can be displayed by page-turning. Accordingly, a display terminal can include a thumbnail generating module, a displaying module, an instruction control module. 1. A method for displaying interface windows on a display terminal comprising:obtaining at least two interface window thumbnails;stacking the at least two interface window thumbnails to display; andreceiving a display instruction; anddisplaying the at least two interface window thumbnails by page-turning according to the display instruction.2. The method of claim 1 , wherein the display instruction comprises a displacement received by the display terminal.3. The method of claim 2 , further comprising:determining whether a coordinate movement direction of the displacement of a gesture is in a first direction range or in a second direction range.4. The method of claim 3 , wherein claim 3 , when the displacement is in the first direction range claim 3 , the method further comprises:determining whether a speed of the displacement is in a first speed range or in a second speed range, andpage-turning a first interface window thumbnail of the at least two interface window thumbnails to display, when the speed of the displacement is in the first speed range, orpage-turning the at least two interface window thumbnails to display, when the speed of the displacement is in the second speed range.5. The method of claim 4 , wherein when the speed of the displacement is in the second speed range claim 4 , the method further comprises:page-turning a number of interface window thumbnails selected from the at least two interface window thumbnails to display, wherein the number corresponds to a number of the displacement.6. ...

Technology for the Preparation of Microparticles

Microspheres are produced by contacting a solution of a macromolecule or small molecule in a solvent with an antisolvent and a counterion, and chilling the solution. The microspheres are useful for preparing pharmaceuticals, nutraceuticals, cosmetic products and the like of defined dimensions. 1a) adding a counterion to a solution containing the compound in a solvent;b) adding an antisolvent to the solution; andc) gradually cooling the solution to a temperature below about 25° C.,. A method of making microparticles of a compound, comprising: This application is a continuation and claims priority under 35 U.S.C. §119(e) to U.S. application Ser. No. 13/250,653, filed Sep. 30, 2011 which claims priority to U.S. application Ser. No. 12/179,520, filed Jul. 24, 2008 which claims priority to U.S. provisional application Ser. No. 60/961,872, entitled “TECHNOLOGY FOR THE PREPARATION OF MICROPARTICLES” to Fang et al. filed Jul. 24, 2007. The subject matter of the provisional application is incorporated in its entirety by reference herein. This application also is related to International PCT Application No. (Attorney Dkt. No. 21865-005WO1/6505PC) filed on the same day herewith. The subject matter of the PCT application is incorporated by reference herein.This application is related to International PCT Application Serial No. (Attorney Docket No. 21865-004WO1/6504PC, filed Jan. 24, 2007), and to U.S. application Ser. No. 11/657,812, filed Jan. 24, 2007 (Attorney Docket No. 21865-004001/6504). This application also is related to published U.S. applications Serial Nos. US20050004020 A1 and US20050112751 A1. Each of these applications is incorporated by reference herein in its entirety.An electronic version of the Sequence Listing is filed herewith, the contents of which are incorporated by reference in their entirety. The computer-readable file, created on Jul. 24, 2008, is 46 kilobytes in size and titled 21865005001SeqList.txt.The preparation and delivery of compounds of ...

Methods, Compounds, and Compositions For Treatment and Prophylaxis in the Respiratory Tract

The present invention provides a method of reducing the quanitity of mucus in the respiratory tract of a subject with elevated levels of mucus in said respiratory tract. The method includes administering to the subject a compound or composition containing a therapeutically effective amount of a fusion protein comprising a sialidase or an active portion thereof and an anchoring domain. The therapeutically effective amount comprises an amount of the fusion protein that results in a reduction of the quanitity of mucus in the respiratory tract after administration of the compound or composition when compared to the quantity of mucus present prior to administration of the compound or composition. 1. A method of reducing the quantity or level of mucus or preventing an increase in the quantity or level of mucus in a respiratory tract of a subject , the method comprising:administering to the subject a compound or composition comprising a therapeutically effective amount of a fusion protein, whereinthe fusion protein comprises at least one catalytic domain of a sialidase, wherein the catalytic domain of the sialidase comprises the sequence of amino acids extending from amino acid 274 to amino acid 666 of SEQ ID NO:12, inclusive, and at least one anchoring domain, wherein the anchoring domain is a glycosaminoglycan (GAG) binding domain of human amphiregulin comprising the amino acid sequence of SEQ ID NO:7; andthe therapeutically effective amount comprises an amount of the fusion protein that results in a reduction of the quanitity of mucus in the respiratory tract after administration of the compound or composition when compared to the quantity of mucus present prior to administration of the compound or composition.2115-. (canceled) This application claims the benefit of U.S. patent application Ser. No. 13/769,095, filed on Feb. 15, 2013, which claims the benefit of U.S. patent application Ser. No. 12/940,742, filed on Nov. 5, 2010, (U.S. Pat. No. 8,398,971) which claims the ...

TOUCH PANEL AND MANUFACTURING METHOD THEREOF

The present invention provides a touch panel including a touch sensor and a connecting board. The touch sensor includes a touch substrate and a sensing electrode matrix with a plurality of connecting ends. The sensing electrode matrix is formed on the touch substrate, wherein the connecting ends of the sensing electrode matrix are separately located at at least two sides of the sensing electrode matrix. The connecting board is connected to the touch sensor, and the conducting wires in the connecting board are electrically connected to the connecting ends of the sensing electrode matrix. Furthermore, a touch panel manufacturing method is also provided. 1. A touch panel , comprising:a touch sensor, including a touch substrate and a sensing electrode matrix with a plurality of connecting ends, wherein the sensing electrode matrix is formed on the surface of the touch substrate and the plurality of connecting ends are separately located at at least two sides of the sensing electrode matrix; anda connecting board with conducting wires disposed thereon, connected to the touch sensor, wherein the conducting wires are electrically connected to the connecting ends of the sensing electrode matrix.2. The touch panel of claim 1 , wherein the sensing electrode matrix is aligned with the edge of the touch substrate.3. The touch panel of claim 2 , wherein the sensing electrode matrix further comprises a plurality of conductive units claim 2 , and the area of each of the conductive unit disposed on the edge of the touch substrate is half of that of each of the conductive unit disposed on the center of the touch substrate claim 2 , wherein a part of the half-size conductive units are assigned to be the connecting ends.4. The touch panel of claim 1 , wherein the connecting board is a flexible printed circuit board claim 1 , and the flexible printed circuit board is partially overlapped and electrically connected with the touch sensor.5. The touch panel of claim 4 , wherein the ...

Method for improving the quality of soy sauce using Bacillus amyloliquefaciens

The present invention provides a method for improving the quality of soy sauce using , which relates to the field of microbiology and food technology. The method comprises inoculating BBE JY06 during soy sauce fermentation. With addition during soy sauce fermentation, the aroma and tastes of soy sauce is improved and the ethyl carbamate content in soy sauce is decreased as well. 1Bacillus amyloliquefaciensBacillus amyloliquefaciens. A method for improving the quality of soy sauce , comprising addition of appropriate amount of BBE JY06 during soy sauce fermentation , wherein said BBE JY06 is conserved in China Center for Type Culture Collection in Wuhan University , Wuhan , Hubei , China on Jul. 2 , 2015 with the code CCTCC NO: M 2015423.2Bacillus amyloliquefaciens. The method of claim 1 , wherein said BBE JY06 is inoculated to a soy sauce fermentation mash at an amount of 1×10˜1×10CFU·mL.3Bacillus amyloliquefaciens. The method of claim 2 , wherein said BBE JY06 is inoculated to said soy sauce fermentation mash at an amount of 1×10CFU·mL.4Bacillus amyloliquefaciens. The method of claim 2 , wherein said BBE JY06 is inoculated to said soy sauce fermentation mash at an amount of 1×10CFU·mL.5Bacillus amyloliquefaciens. The method of claim 1 , comprising inoculating said BBE JY06 on the 0˜3day from the beginning of the fermentation of soy sauce.6. The method of claim 1 , comprising the steps of:{'i': 'Aspergillus oryzae', '1) koji preparation: defatted soybean and parched and crushed wheat are mixed, soaked, sterilized and then cooled; bran and wheat flour are added to the cooled mixture, and spore is inoculated in the mixture at the same time; when koji color turns greenish yellow, mature koji is obtained; and'}{'i': Bacillus amyloliquefaciens', 'Torulopsis glabrata', 'Zygosaccharomyces rouxii, 'sup': rd', '7', '−1, '2) soy sauce fermentation: mature koji and brine are mixed together and the fermentation begins; BBE JY06 is inoculated on the 0˜3day from the beginning of ...

Epigenomic Markers of Cancer Metastasis

Methods and kits for assessing risk of metastasis in a cancer patient identified as having breast cancer, colon cancer or glioma use analysis of a classifier for CpG island methylator phenotype. 1. A method for assessing risk of metastasis in a cancer patient identified as having breast cancer , colon cancer or glioma , comprising the steps of:(a) obtaining a sample of tumor tissue from the patient;(b) evaluating the sample for hypermethylation of a plurality of genes, and(c) based on the evaluation of step (b) determining whether and/or to what extent the patient is at risk of cancer metastasis,wherein the plurality of genes includes at least three genes selected from the group consisting of: ALX4, CRABP1, ADAM23, MOXD1, CHST2, FAM89A, RNH1, B3GNT5, KCNIP1, SLC16A12, RUNX3, LYN, PSAT1, RASGRF2, SOX8, ARHGEF7, ADAM12, PYGO1, P2RY1, FLJ25477, FBN1, PROX1, FOXL2, KCNJ2, SMOC1, MCF2L2, BMP3, TRIM29, GRIK1, ALK, C2orf32, VIM, AKAP12, EIF5A2, DZIP1, FLJ34922, TMEM22, LBX1, GJA7, HAAO, KLK10, ZAR1, DPYSL5, SLIT2, RGS17, KIAA1822, PTGFR, FBN2, ST6GALNAC3, VAX1, GPR83, TBX2, SIX3, ACADL, and ASRGL1.2. The method of claim 1 , wherein the number of genes evaluated is from 3 to 20 genes selected from the group consisting of ALX4 claim 1 , CRABP1 claim 1 , ADAM23 claim 1 , MOXD1 claim 1 , CHST2 claim 1 , FAM89A claim 1 , RNH1 claim 1 , B3GNT5 claim 1 , KCNIP1 claim 1 , SLC16A12 claim 1 , RUNX3 claim 1 , LYN claim 1 , PSAT1 claim 1 , RASGRF2 claim 1 , SOX8 claim 1 , ARHGEF7 claim 1 , ADAM12 claim 1 , PYGO1 claim 1 , P2RY1 claim 1 , FLJ25477 claim 1 , FBN1 claim 1 , PROX1 claim 1 , FOXL2 claim 1 , KCNJ2 claim 1 , SMOC1 claim 1 , MCF2L2 claim 1 , BMP3 claim 1 , TRIM29 claim 1 , GRIK1 claim 1 , ALK claim 1 , C2orf32 claim 1 , VIM claim 1 , AKAP12 claim 1 , EIF5A2 claim 1 , DZIP1 claim 1 , FLJ34922 claim 1 , TMEM22 claim 1 , LBX1 claim 1 , GJA7 claim 1 , HAAO claim 1 , KLK10 claim 1 , ZAR1 claim 1 , DPYSL5 claim 1 , SLIT2 claim 1 , RGS17 claim 1 , KIAA1822 claim 1 , PTGFR claim 1 , ...

Technology for the Preparation of Microparticles

Microspheres are produced by contacting a solution of a macromolecule or small molecule in a solvent with an antisolvent and a counterion, and chilling the solution. The microspheres are useful for preparing pharmaceuticals, nutraceuticals, cosmetic products and the like of defined dimensions. 1a) adding a counterion to a solution containing the compound in a solvent;b) adding an antisolvent to the solution; andc) gradually cooling the solution to a temperature below about 25° C.,. A method of making microparticles of a compound, comprising: This application is a continuation and claims priority to U.S. application Ser. No. 15/369,734, filed Dec. 5, 2016, which is a continuation and claims priority to U.S. application Ser. No. 15/080,399, filed Mar. 24, 2016, which claims priority to U.S. application Ser. No. 14/742,612, filed Jun. 17, 2015, which claims priority to U.S. application Ser. No. 14/341,502, filed Jul. 25, 2014, which claims priority to U.S. application Ser. No. 13/874,424, filed Apr. 30, 2013, which claims priority to U.S. application Ser. No. 13/250,653, filed Sep. 30, 2011, which claims priority to U.S. application Ser. No. 12/179,520, filed Jul. 24, 2008, which claims priority to U.S. provisional application Ser. No. 60/961,872, entitled “TECHNOLOGY FOR THE PREPARATION OF MICROPARTICLES” to Fang et al. filed Jul. 24, 2007. This application also is related to International PCT Application No. (Attorney Dkt. No. 21865-005WO1/6505PC) filed on the same day herewith. Each of these applications are incorporated by reference herein in its entirety.This application is related to International PCT Application Serial No. (Attorney Docket No. 21865-004WO1/6504PC, filed Jan. 24, 2007), and to U.S. application Ser. No. 11/657,812, filed Jan. 24, 2007 (Attorney Docket No. 21865-004001/6504). This application also is related to published U.S. applications Serial Nos. US20050004020 A1 and US20050112751 A1. Each of these applications are incorporated by reference ...

DEEP WATER POWER GENERATION STATION, POWER STATION, MARINE POWER PLANT AND OFFSHORE FLOATING CITY THEREOF

A deep water power generation station, a power station, a marine power plant and an offshore floating city thereof includes a water tunnel pipe, where a length H is in a range of 0≦H≦10000 m; an upper end of the water tunnel pipe is connected to a hydraulic turbine through a horizontal water tunnel pipe, the hydraulic turbine is connected to a generator through a coupler, the hydraulic turbine is installed on a ship, a lower end of the water tunnel pipe is in communication with a horizontal speed-increasing water inlet pipe, the horizontal speed-increasing water inlet tunnel pipe is hung on the vertical speed-increasing water tunnel pipe through a bearing, an upper end of the water tunnel pipe is provided with a sealing top cover having an adjustable valve, and the rear of the water inlet pipe is connected to a flake-like steering empennage. 12. A deep water power generation station , a power station , a marine power plant , and an offshore floating city thereof , comprising a vertical speed-increasing water tunnel pipe that increases a water velocity from V≦0-1 m/sec to V≧200 m/sec , wherein an upper end of the water tunnel pipe is installed on a ship or installed on a structural member connected to barrage infrastructure or the land , a length H of the water tunnel pipe is in a range of 0≦H≦10000 m , a lower end of the water tunnel pipe is in a floating state (with a weight or without a weight) or is fixedly bonded to a ground pile having a water inlet , the upper end of the water tunnel pipe is connected to a hydraulic turbine through a horizontal water tunnel pipe , and the hydraulic turbine is connected to a generator through a coupler , to provide a hydropower station formed by a power source; alternatively , the horizontal water tunnel pipe provides a power source to a driving turbine of a propeller of a ship by using a parallel pipe , the hydraulic turbine is installed on the ship or is installed on a structural member connected to a barrage or the land , ...

Technology for the Preparation of Microparticles

Microspheres are produced by contacting a solution of a macromolecule or small molecule in a solvent with an antisolvent and a counterion, and chilling the solution. The microspheres are useful for preparing pharmaceuticals, nutraceuticals, cosmetic products and the like of defined dimensions. 1a) adding a counterion to a solution containing the compound in a solvent;b) adding an antisolvent to the solution; andc) gradually cooling the solution to a temperature below about 25° C., whereby a composition containing microparticles comprising the compound is formed, wherein steps a), b) and c) are performed simultaneously, sequentially, intermittently, or in any order.. A method of making microparticles of a compound, comprising: This application is a continuation and claims priority to U.S. application Ser. No. 13/874,424, filed Apr. 30, 2013, which claims priority to U.S. application Ser. No. 13/250,653, filed Sep. 30, 2011, which claims priority to U.S. application Ser. No. 12/179,520, filed Jul. 24, 2008, which claims priority to U.S. provisional application Ser. No. 60/961,872, entitled “TECHNOLOGY FOR THE PREPARATION OF MICROPARTICLES” to Fang et al. filed Jul. 24, 2007. This application also is related to International PCT application No. (Attorney Dkt. No. 21865-005WO1/6505PC) filed on the same day herewith. Each of these applications is incorporated by reference herein in its entirety.This application is related to International PCT application Serial No. (Attorney Docket No. 21865-004WO1/6504PC, filed Jan. 24, 2007), and to U.S. application Ser. No. 11/657,812, filed Jan. 24, 2007 (Attorney Docket No. 21865-004001/6504). This application also is related to published U.S. applications Serial Nos. US20050004020 A1 and US20050112751 A1. Each of these applications is incorporated by reference herein in its entirety.An electronic version of the Sequence Listing is filed herewith, the contents of which are incorporated by reference in their entirety. The computer- ...

THREE-DIMENSIONAL POROUS POLYURETHANE SCAFFOLD FOR REPAIRING CENTRAL NERVE INJURIES AND PREPARATION METHOD THEREOF

A three-dimensional porous polyurethane scaffold for repairing central nerve injuries and a preparation method are disclosed. The scaffold includes three-dimensional porous polyurethane, wherein the compression modulus of the three-dimensional porous polyurethane is 0.001-10.0 MPa and the pore diameter is 10-200 μm. The three-dimensional porous polyurethane scaffold has an efficient central nerve repair function without additionally inoculating functional cells or factors and can partially restore the original nerve function of tested animals, the preparation method is simple and it has a great prospect of application. 112.-. (canceled)13. A method comprising using a three-dimensional porous polyurethane in preparation of a scaffold for repairing central nerve injuries , wherein the scaffold for repairing central nerve injuries comprises three-dimensional porous polyurethane , the compression modulus of the three-dimensional porous polyurethane is 0.001-10.0 MPa; and the pore diameter of the three-dimensional porous polyurethane is 10-200 μm.14. The method according to claim 13 , wherein the compression modulus of the three-dimensional porous polyurethane is 0.01-7.0 MPa; and the pore diameter of the three-dimensional porous polyurethane is 20-150 μm.15. The method according to claim 13 , wherein the compression modulus of the three-dimensional porous polyurethane is 0.1-3.0 MPa.16. The method according to claim 13 , wherein the porosity of the three-dimensional porous polyurethane is 30-95%.17. The method according to claim 15 , wherein the porosity of the three-dimensional porous polyurethane is 30-95%.18. The method according to claim 16 , wherein the porosity of the three-dimensional porous polyurethane is 70-90%.19. The method according to claim 13 , wherein the polyurethane comprises biodegradable polyurethane; and the biodegradable polyurethane comprises thermoplastic biodegradable polyurethane or crosslinked biodegradable polyurethane.20. The method ...

NUCLEOTIDE COMPOSITION AND APPLICATION IN FOOD THEREOF

A nucleotide composition used as a food additive consists of 58-72% CMP, 6-14% AMP, 10-18% UMP and 8-14% GMP, or consists of 58-70% CMP, 7.5-12.5% AMP, 12-16.5% UMP, 10-13% GMP and 0-2.5% IMP. The composition is used to prepare foods, such as an infant food and a dairy product, and achieves the following effects: improving immunostimulation, promoting growth and development, facilitating repair after intestinal injury, promoting the growth of intestinal beneficial microorganisms, and/or any combination thereof. 1. A nucleotide composition as a food additive , wherein on a weight basis , the composition substantially comprises components CMP , AMP , UMP and GMP , and wherein proportions of the components are CMP: 58˜72% , AMP: 6˜14% , UMP: 10˜18% and GMP: 8˜14% , and a sum of the components is 100%.2. The composition according to claim 1 , wherein the proportions of the components are CMP: 60˜70% claim 1 , AMP: 8˜12% claim 1 , UMP: 12˜16% and GMP: 10˜12% claim 1 , and a sum of the components is 100%.3. The composition according to claim 1 , wherein the proportions of the components are CMP: 60˜65% claim 1 , AMP: 10˜12% claim 1 , UMP: 14˜16% and GMP: 11˜12% claim 1 , and a sum of the components is 100%.4. The composition according to claim 1 , wherein the proportions of the components are CMP: 65˜70% claim 1 , AMP: 8˜10% claim 1 , UMP: 12˜14% and GMP: 10˜11% claim 1 , and a sum of the components is 100%.5. The composition according to claim 1 , wherein the proportions of the components are:CMP: 60%, AMP: 12%, UMP: 16% and GMP: 12%;CMP: 65%, AMP: 10%, UMP: 14% and GMP: 11%; orCMP: 70%, AMP: 8%, UMP: 12% and GMP: 10%.6. A nucleotide composition as a food additive claim 1 , wherein on a weight basis claim 1 , the composition substantially comprises components CMP claim 1 , AMP claim 1 , UMP claim 1 , GMP and IMP claim 1 , and wherein proportions of the components are CMP: 58˜70% claim 1 , AMP: 7.5˜12.5% claim 1 , UMP: 12˜16.5% claim 1 , GMP: 10˜13% and IMP: 0˜2.5% claim ...

TECHNOLOGY FOR PREPARATION OF MACROMOLECULAR MICROSPHERES

Microspheres are produced by contacting an aqueous solution of a protein or other macromolecule with an organic solvent and a counterion, and chilling the solution. The microspheres are useful for preparing pharmaceuticals of defined dimensions. 1141-. (canceled)142. Microparticles comprising a polypeptide comprising SEQ ID NO:17 , prepared by a process comprising:a) adding a counterion selected from the group consisting of sodium citrate, sodium sulfate, calcium sulfate, potassium sulfate and magnesium sulfate to an aqueous solution comprising a polypeptide comprising SEQ ID NO:17, whereby an aqueous composition is formed;b) adding isopropanol to the aqueous composition of (a) whereby a second aqueous composition is formed; andc) cooling the second aqueous composition of (b) at a rate of 0.1° C./min to 10° C./min to a temperature between 4° C. and −45° C., whereby microparticles comprising a polypeptide compromising SEQ ID NO: 17 are formed.143. The microparticles of wherein step c) of the method comprises cooling the second aqueous composition of (b) at a rate of 0.5° C./min to 2° C./min.144. The microparticles of wherein step c) of the method comprises cooling the second aqueous composition of (b) at a rate of 0.5° C./min to 1° C./min.145. The microparticles of wherein the counterion is sodium sulfate.146. The microparticles of wherein the counterion is magnesium sulfate.147. The microparticles of wherein the method further comprises cooling the composition containing microparticles comprising a polypeptide compromising SEQ ID NO: 17 to a temperature of between about −45° C. and about −80° C.148. The microparticles of wherein step c) of the method comprises cooling the second aqueous composition of (b) to a temperature between 2° C. and −20° C. degrees.149. The microparticles of wherein step b) of the method comprises adding isopropanol to about 10% v/v.150. The microparticles of wherein step b) of the method comprises adding isopropanol to about 20% v/v.151. The ...

OPTIMIZED REGULATING AND CONTROLLING METHOD AND SYSTEM FOR INTEGRATED ELECTRICITY AND HEAT SYSTEM WITH HEAT PUMPS

The present application provides an optimized regulating and controlling method and system for an integrated electricity and heat system with heat pumps, relating to the technical field of energy operation. According to the present application, regulating and controlling can be performed by regarding units as different agents and taking maximization of the self-interest of each agent as the objective, so that the load demands of heat and power consumers can be met, and each unit agent can be satisfied with its payoff to the greatest extent. The method includes: S1. establishing a composition and structure framework of the integrated electricity and heat system with heat pumps, and establishing an output model of each unit; S2. establishing a payoff function model of each unit in the integrated electricity and heat system with heat pumps; S3. establishing a non-cooperative game model of the integrated electricity and heat system with heat pumps; and S4. solving the game model by using a particle swarm optimization algorithm to obtain a heat and power scheduling optimization scheme of each unit. The technical solution provided by the present application is applicable to a process of regulating an integrated electricity and heat system with heat pumps. 1. An optimized regulating and controlling method for an integrated electricity and heat system with heat pumps , wherein the method comprises the following steps:S 1. establishing a composition and structure framework of the integrated electricity and heat system with heat pumps, and establishing an output model of each unit;S2. establishing a payoff function model of each unit in the integrated electricity and heat system with heat pumps;S3. establishing a non-cooperative game model of the integrated electricity and heat system with heat pumps; andS4. solving the game model by using a particle swarm optimization algorithm to obtain a heat and power scheduling optimization scheme of each unit.2. The optimized regulating ...

Technology for the Preparation of Microparticles

Microspheres are produced by contacting a solution of a macromolecule or small molecule in a solvent with an antisolvent and a counterion, and chilling the solution. The microspheres are useful for preparing pharmaceuticals, nutraceuticals, cosmetic products and the like of defined dimensions. 1a) adding a counterion to a solution containing the compound in a solvent;b) adding an antisolvent to the solution; andc) gradually cooling the solution to a temperature below about 25° C., whereby a composition containing microparticles comprising the compound is formed, wherein steps a), b) and c) are performed simultaneously, sequentially, intermittently, or in any order.. A method of making microparticles of a compound, comprising: This application is a continuation and claims priority to U.S. application Ser. No. 15/635,169, filed Jun. 27, 2017, which is a continuation and claims priority to U.S. application Ser. No. 15/369,734, filed Dec. 5, 2016, which is a continuation and claims priority to U.S. application Ser. No. 15/080,399, filed Mar. 24, 2016, which claims priority to U.S. application Ser. No. 14/742,612, filed Jun. 17, 2015, which claims prioritiy to U.S. application Ser. No. 14/341,502, filed Jul. 25, 2014, which claims priority to U.S. application Ser. No. 13/874,424, filed Apr. 30, 2013, which claims priority to U.S. application Ser. No. 13/250,653, filed Sep. 30, 2011, which claims priority to U.S. application Ser. No. 12/179,520, filed Jul. 24, 2008, which claims priority to U.S. provisional application Ser. No. 60/961,872, entitled “TECHNOLOGY FOR THE PREPARATION OF MICROPARTICLES” to Fang et al. filed Jul. 24, 2007. This application also is related to International PCT Application No. (Attorney Dkt. No. 21865-005WO1/6505PC) filed on the same day herewith. Each of these applications are incorporated by reference herein in its entirety.This application is related to International PCT Application Serial No. (Attorney Docket No. 21865-004WO1/6504PC, filed ...

Bi-directional transceiver with time synchronization

A system or a network may include an optoelectronic module that includes an optical transmitter optically coupled with an optical fiber, and a controller communicatively coupled to the optical transmitter. The controller may be configured to operate the optical transmitter to transmit data signals through the optical fiber. The optoelectronic module may be configured to transmit time synchronization signals through the optical fiber along with the data signals.

CLIENT CACHING IDENTIFICATION TRACKING

Embodiments are directed towards employing multiple profiles to track identification of users across multiple domains. Multiple application-domain profiles and multiple web-domain profiles may each include a statistical identifier. A profile enrichment store may be generated from the application-domain profiles and web-domain profiles, where each entry in the profile enrichment store may be based on statistical identifiers. The profile enrichment store may be utilized to determine categories associated with a statistical identifier for a request from a client device. A targeted advertisement may be determined based on the determined category and may be provided to the client device. A client caching identifier may be used in a mobile web domain, in combination with the statistical identifier, to track mobile web users. If a request is associated with a profile that includes an affirmative opt-out flag, categories in the profile enrichment store for a corresponding statistical identifier may be cleaned up. 1. A computer-implemented method comprising:identifying a client device configured to execute a web browser and a native application, the client device being characterized by one or more client device attributes commonly retrievable by each of the web browser and the native application, and the one or more client device attributes of the client device including a unique device identifier;generating a statistical identifier to represent the client device, the statistical identifier being generated using the one or more client device attributes;receiving, from the client device, a first communication requesting first content data, the first communication originating from the native application executing on the client device;tracking native application activity performed by the client device executing the native application, the native application activity being tracked using the unique device identifier associated with the client device, and the native application ...

Salt-reduced Fermentation Method for High-salt Dilute-state Fermented Soy Sauce

The present disclosure discloses a salt-reduced fermentation method for high-salt dilute-state fermented soy sauce, and belongs to the technical field of fermentation engineering. The present disclosure separates and screens JL-5 and JDF-2 which inhibit the growth of spoilage bacteria from low-salt soy sauce mash, and by changing the microbial fermentation process of high-salt dilute-state soy sauce, the strains obtained by screening are used for the fermentation of low-salt soy sauce mash. Without changing the flavor and quality of soy sauce, low-salt fermentation of the soy sauce is enabled to proceed normally, and the biogenic amine content is less than 100 mg L, and the number of spoilage bacteria in the soy sauce are reduced. The prepared low-salt soy sauce has an amino acid nitrogen content of greater than 1.2 g·100 mL, contents of various spoilage bacteria of less than 1.0×10CFU·g, a NaCl concentration of no more than 10 g·100 mL, and a sodium content of less than or equal to 420 mg·10 mL. Without the addition of preservatives, the quality stability is the same as that of soy sauce without salt reduction. 1. A method for producing high-salt dilute-state soy sauce , comprising cooking , koji making , and fermentation;{'sup': '−1', 'i': Weissella paramesenteroides', 'W. paramesenteroides', 'Bacillus amyloliquefaciens', 'B. amyloliquefaciens', 'W. paramesenteroids', 'B. amyloliquefaciens, 'the fermentation comprising: mixing finished koji with brine at a volume ratio of 1:(2-3), so that the final concentration of salt in the system is less than or equal to 12 g·100 mL, adding () JL-5 and () JDF-2, or a composition containing the JL-5 and the JDF-2, and then performing fermentation at 25-30° C. for at least 30 days;'}{'i': 'W. paramesenteroids', 'wherein the JL-5 is preserved in the China Center for Type Culture Collection on Jun. 9, 2021, with a preservation number of CCTCC NO: M 2021707; and'}{'i': 'B. amyloliquefaciens', 'wherein the JDF-2 is preserved in the ...

Autonomous Item Generation

An autonomous item generation system implements a trained machine learning model configured to output fabrication instructions for generating an item and metadata describing the item, automatically and independent of user input. Fabrication instructions output by the machine learning model are transmitted to a fabrication device for generating the item. The autonomous item generation system generates a listing for the item based on the metadata output by the machine learning model and publishes the listing to a virtual marketplace. Analytics data describing feedback for the item listing is used to generate training data for the machine learning model. The training data is input to the machine learning model, which causes the machine learning model to refine at least one control parameter according to a loss function that penalizes negative differences between predicted and observed feedback data for the item. The machine learning model with the refined parameter(s) is then used by the autonomous item generation system to generate fabrication instructions and metadata for an additional item. 1. A method for autonomous item generation implemented by at least one computing device , the method comprising:generating, using at least one machine learning model, instructions for fabricating an item and metadata describing the item;fabricating the item by communicating the instructions for fabricating the item to a fabrication device;creating a listing for the item using the metadata;publishing the listing to a virtual marketplace and obtaining analytics data describing one or more interactions with the listing via the virtual marketplace;forming training data using the analytics data and modifying a parameter of the at least one machine learning model based on the training data; andgenerating, using the at least one machine learning model with the modified parameter, instructions for fabricating a different item.2. The method of claim 1 , wherein the method is performed ...

Technology for Preparation of Macromolecular Microspheres

Microspheres are produced by contacting an aqueous solution of a protein or other macromolecule with an organic solvent and a counterion, and chilling the solution. The microspheres are useful for preparing pharmaceuticals of defined dimensions. 1. Microparticles comprising a polypeptide comprising the amino acid of SEQ ID NO:17 prepared by a method comprising:a) adding a counterion selected from the group consisting of sodium citrate, sodium sulfate, calcium sulfate, potassium sulfate and magnesium sulfate to an aqueous solution comprising a polypeptide comprising the amino acid sequence of SEQ ID NO:17, whereby an aqueous composition is formed;b) adding isopropanol to the aqueous composition of (a) whereby a second aqueous composition is formed; andc) cooling the second aqueous composition of (b) at a rate of 0.1° C./min to 10° C./min to a temperature between 4° C. and −45° C., whereby a composition containing polypeptide microparticles comprising the polypeptide is formed.2. The microparticles of claim 1 , wherein the cooling rate is 0.5° C./min to 2° C./min.3. The microparticles of claim 1 , wherein the cooling rate is 0.5° C./min to 1° C./min.4. The microparticles of claim 1 , wherein the counterion is sodium citrate.5. The microparticles of claim 1 , wherein the counterion is magnesium sulfate.6. The microparticles of claim 1 , wherein the method of making further comprises cooling the composition containing polypeptide microparticles comprising the polypeptide to a temperature of between about −45° C. and about −80° C.7. The microparticles of claim 1 , wherein step c) comprises cooling the second aqueous composition of (b) to a temperature between 2° C. and −20° C. degrees.8. The microparticles of claim 1 , wherein step b) comprises adding isopropanol to about 10% v/v.9. The microparticles of claim 1 , wherein step b) comprises adding isopropanol to about 20% v/v.10. The microparticles of claim 1 , wherein wherein step b) comprises adding isopropanol to about ...

PAGE DISPLAY METHOD, APPARATUS AND TERMINAL

The embodiments of the disclosure provide a page display method and apparatus, belonging to the field of terminals. The method comprises monitoring the page browsing mode of a browser while running the browser; determining a changed page browsing mode, if the page browsing mode of the browser is changed; and displaying a tips button on the current page of the browser, if the changed page browsing mode is a specified mode. The apparatus comprises a monitoring module, a determining module, and a displaying module. Thereby, the tips-making process while switching modes is simplified. The tips button is displayed on a specific location to remind users, without breaking the continuous browsing via the browser, so that non-trace switch can be achieved when the browser changes its page browsing mode. 1. A page display method , comprising:monitoring a page browsing mode of a browser while running the browser;determining a changed page browsing mode, if the page browsing mode of the browser is changed;displaying a tips button on a current page of the browser, if the changed page browsing mode is a specified mode;displaying an information box including description information of the specified mode, when displaying the tips button on the current page of the browser; andhiding the information box, when receiving a click operation outside the information box or after the information box has been displayed for a predetermined period of time.2. The method of claim 1 , wherein claim 1 , the specified mode comprises a traceless browsing mode and a security browsing mode claim 1 , and the step of displaying a tips button on a current page of the browser comprises:displaying a traceless browsing mode related tips button on the current page of the browser, if the changed page browsing mode is the traceless browsing mode; anddisplaying a current page related tips button on the current page of the browser according to the current page of the browser and a browsing rule of the security ...

Technology for the Preparation of Microparticles

Microspheres are produced by contacting a solution of a macromolecule or small molecule in a solvent with an antisolvent and a counterion, and chilling the solution. The microspheres are useful for preparing pharmaceuticals, nutraceuticals, cosmetic products and the like of defined dimensions. 1a) adding a counterion to a solution containing the compound in a solvent;b) adding an antisolvent to the solution; andc) gradually cooling the solution to a temperature below about 25° C., whereby a composition containing microparticles comprising the compound is formed, wherein steps a), b) and c) are performed simultaneously, sequentially, intermittently, or in any order.. A method of making microparticles of a compound, comprising: This application is a continuation and claims priority to U.S. application Ser. No. 15/080,399, filed Mar. 24, 2016, which claims priority to U.S. application Ser. No. 14/742,612, filed Jun. 17, 2015, which claims priority to U.S. application Ser. No. 14/341,502, filed Jul. 25, 2014, which claims priority to U.S. application Ser. No. 13/874,424, filed Apr. 30, 2013, which claims priority to U.S. application Ser. No. 13/250,653, filed Sep. 30, 2011, which claims priority to U.S. application Ser. No. 12/179,520, filed Jul. 24, 2008, which claims priority to U.S. provisional application Ser. No. 60/961,872, entitled “TECHNOLOGY FOR THE PREPARATION OF MICROPARTICLES” to Fang et al. filed Jul. 24, 2007. This application also is related to International PCT Application No. (Attorney Dkt. No. 21865-005WO1/6505PC) filed on the same day herewith. Each of these applications is incorporated by reference herein in its entirety.This application is related to International PCT Application Serial No. (Attorney Docket No. 21865-004WO1/6504PC, filed Jan. 24, 2007), and to U.S. application Ser. No. 11/657,812, filed Jan. 24, 2007 (Attorney Docket No. 21865-004001/6504). This application also is related to published U.S. application Serial Nos. US20050004020 A1 ...

TOUCH PANEL AND MANUFACTURING METHOD THEREOF

A touch panel is formed by firstly forming a film layer on a first plate, and next, sequentially forming a buffer layer on the film layer, forming a sensing layer on the buffer layer, forming a second plate on the sensing layer. After the foregoing formation procedures, the first substrate layer is removed from the film layer. Next, a cover is attached to the film layer. In this way, the film layer is located between the cover and the buffer layer. Finally, the second substrate layer is removed from the sensing layer, so as to form a touch panel with the features of light weight, thin thickness and low costs. 1. A method for manufacturing a touch panel comprisingproviding a first plate;forming a film layer on said first plate;forming a buffer layer on said film layer, so said film layer being between said first plate and said buffer layer; said buffer layer comprising an inorganic material and an organic material;forming a sensing layer on said buffer layer; so said buffer layer being between said film layer and said sensing layer;forming a second plate on said sensing layer; so said sensing layer being between said buffer layer and said second plates;removing said first plate from said film layer;attaching a cover on said film layer by a binding layer, said binding layer being between said cover and said film layer; andremoving said second plate.2. The method for manufacturing a touch panel as set forth in claim 1 , further comprisingadding a first adhering layer on said first plate, so said first adhering layer being between said first plate and said film layer; andattaching said film layer to said first plate via a first adhering layer.3. The method for manufacturing claim 1 , a touch panel as set forth in claim 1 , further comprisingattaching said second plate to said sensing layer via a second adhering layer.4. The method for manufacturing a touch panel as set forth in claim 1 , further comprisingforming a protection layer on said sensing layer, so said sensing ...

TOUCH PANEL AND MANUFACTURING METHOD THEREOF

A touch panel is formed by firstly forming a film layer on a first plate, and next, sequentially forming a buffer layer on the film layer, forming a sensing layer on the buffer layer, forming a second plate on the sensing layer. After the foregoing formation procedures, the first plate is removed from the film layer. Next, a cover is attached to the film layer. In this way, the film layer is located between the cover and the buffer layer. Finally, the second plate is removed from the sensing layer, so as to form a touch panel with the features of light weight, thin thickness and low costs. 1. A touch panel , comprisinga cover;a binding layer;a film layer;a buffer layer;a sensing layer;said binding layer being between said cover and said film layer;said film layer being between said binding layer and said buffer layer;said buffer layer being between said film layer and said sensing layer; andsaid buffer layer comprising an inorganic material and an organic material.2. The touch panel as set forth in claim 1 , comprisingsaid film layer being formed with polyimide (PI).3. The touch panel as set forth in claim 1 , comprisingsaid film layer being formed with a material selected from the group consisting of polypropylene (PP), polystyrene (PS), acrylonitrile-butadiene-styrene (ABS), polyethylene terephthalate (PET), polyvinyl chloride (PVC), polycarbonate (PC), polyethylene (PE), polymethyl methacrylate (PMMA), polytetrafluoro ethylene (PTFE), cyclic olefin copolymer (COP) or a combination thereof.4. The touch panel as set forth in claim 1 , comprisingsaid film layer having, a thickness of 0.1 μm to 15 μm.5. The touch panel as set forth in claim 1 , comprisingsaid film layer having a thickness of 2 μm to 5 μm.6. The touch panel as set forth in claim 1 , comprisingsaid inorganic material comprising titanium oxide and silicon oxide.7. The touch panel as set forth in claim 1 , comprisingsaid inorganic material comprising zirconium oxide.8. The touch panel as set forth in ...

MAIN DRIVE DEVICE OF PLANOCENTRIC SET FOR THREE ARMED FORCES

A main drive device of a planocentric set for three armed forces, including inner ring, outer ring, rolling column between the inner and outer rings at a side closer to the inner ring, and rolling pin shaft pairs installed between the inner and outer rings at a side closer to the outer ring; the inner ring is installed on an eccentric shaft and rotates driven by the eccentric shaft; the eccentric shaft is driven by a prime mover; when the rolling column is in contact with the inner ring, it contacts one of the two neighboring rolling pin shaft pairs to transmit power to the rolling pin shaft pairs in clockwise and counter-clockwise rotation; the rolling pin shaft pair drives the outer ring to rotate; the outer ring drives a planet wheel spoke to rotate, to drive a planocentric set planet wheel, and implement drive of a planocentric set. 1. A main drive device of a planocentric set for three armed forces , installed on a bearing position of a planocentric set planet wheel , and directly transferring power of a prime mover to the planet wheel to drive the planet wheel to implement differential rotation , wherein the main drive device of a planocentric set mainly comprises an inner ring , an outer ring , a rolling column , and rolling pin shaft pairs; the inner ring is installed on an eccentric shaft and rotates driven by the eccentric shaft; the eccentric shaft is driven by the prime mover; the rolling column is installed between the inner ring and the outer ring and at a side closer to the inner ring; the rolling pin shaft pair is installed between the inner ring and the outer ring and at a side closer to the outer ring; when the rolling column is in contact with the inner ring to transfer the power , the rolling column is in contact with one of the two neighboring rolling pin shaft pairs to transmit the power to the rolling pin shaft pairs in clockwise rotation and counter-clockwise rotation; the rolling pin shaft pair drives the outer ring to rotate; the outer ring ...

Behavior Prediction Method, Behavior Prediction Apparatus and Vehicle Control Apparatus

A behavior prediction apparatus specifies a first object that affects a behavior of a vehicle from objects present around the vehicle. The behavior prediction apparatus performs a prediction process of extracting a second object that affects a behavior of the first object among a plurality of objects present around the first object and predicting a behavior. The behavior prediction apparatus sets the extracted second object as a new first object, and performs a prediction process of extracting a new second object affecting the behavior of the new first object and predicting the behavior. The behavior prediction apparatus repeats the prediction process by a predetermined number of times. The behavior prediction apparatus predicts the behavior of the first object in the first prediction process based on the behavior of each of the second objects subjected to the prediction process. 1. A behavior prediction method for predicting a behavior of an object around a vehicle , the method comprising:detecting the object around the vehicle;specifying a first object that affects a behavior of the vehicle among the detected object;performing a prediction process that includes a process of extracting a second object that affects a behaviors of the first object among a plurality of objects present around the first object and predicting a behavior and a process of setting the extracted second object as a new first object, extracting a new second object that affects a behavior of the new first object and predicting a behavior;repeating the prediction process by a predetermined number of extraction times; andpredicting the behavior of the first object during the first prediction process based on the behaviors of the n (n: a natural number corresponding to the predetermined number of times) second objects subjected to the prediction process.2. The behavior prediction method according to claim 1 , whereina first area is set around the vehicle based on a traveling state of the vehicle ...

Driving Assistance Method and Driving Assistance Device

A driving assistance method includes: detecting a first other vehicle entering an intersection on a first route where a host vehicle is traveling from a second route; predicting whether or not the first other vehicle will stop in the intersection, and predicting a stop position of the first other vehicle; calculating a minimum distance of a first gap between a vehicle body of the first other vehicle and a surrounding object around the first other vehicle or between the vehicle body of the first other vehicle and a road edge of a travel lane of the first other vehicle when the first other vehicle stops at the predicted stop position; and predicting according to the calculated minimum distance whether or not a second other vehicle, which is a following vehicle behind the first other vehicle, may slip through the first gap from behind the first other vehicle. 1. A driving assistance method comprising:detecting a first other vehicle entering an intersection on a first route where a host vehicle is traveling from a second route different from the first route;predicting whether or not the first other vehicle will stop in the intersection, and predicting a stop position of the first other vehicle when the first other vehicle is predicted to stop in the intersection;calculating a minimum distance of a first gap between a vehicle body of the first other vehicle and a surrounding object around the first other vehicle or between the vehicle body of the first other vehicle and a road edge of a travel lane of the first other vehicle when the first other vehicle stops at the predicted stop position; andpredicting according to the calculated minimum distance whether or not a second other vehicle, which is a following vehicle behind the first other vehicle, may slip through the first gap from behind the first other vehicle.2. The driving assistance method according to claim 1 , wherein when a priority for the host vehicle to travel on a route to pass through the intersection is ...

SMART MEAL ORDERING METHOD AND DEVICE

A smart meal ordering method comprises: conducting body sensing of a diner by a body sensing hardware of a smart meal ordering device; outputting a meal ordering interface by a display screen of a smart meal ordering device in response to sensing that the diner has taken a seat, and obtaining information of one or more dishes selected by the diner on the meal ordering interface; and in response to sensing that the diner has left the seat, sending a total price of the dishes and identification information of the smart meal ordering device to a server. 1. A smart meal ordering method , comprising:conducting body sensing of a diner by a body sensing hardware of a smart meal ordering device;outputting a meal ordering interface by a display screen of a smart meal ordering device in response to sensing that the diner has taken a seat, and obtaining information of one or more dishes selected by the diner on the meal ordering interface; andin response to sensing that the diner has left the seat, sending a total price of the dishes and identification information of the smart meal ordering device to a server.2. The method according to claim 1 , wherein:a graphic code generated based on the identification information of the smart meal ordering device is attached to the smart meal ordering device; andthe graphic code is configured for scanning by a client device of the diner and for establishing by the client device or the server a bundling relationship between the identification information identified from the graphic code and an account of the diner.3. The method according to claim 1 , further comprising:collecting a facial image of the diner by a camera; anduploading the collected facial image and the identification information of the smart meal ordering device to the server, for the server to bundle the identification information with a payment account associated with the facial image.4. The method according to claim 1 , further comprising:obtaining user information of the ...

Method for extracting alpha-ketoglutarate and pyruvate simultaneously from microbial fermentation broth or enzymatic conversion solution

The present disclosure provides a method for extracting alpha-ketoglutarate and pyruvate simultaneously from microbial fermentation broth or enzyme transformation solution, which is related to the technical field of biological separation and extraction. The method comprises the following steps: centrifuging the microbial fermentation broth or enzymatic conversion solution containing α-KG and PA to remove the cells and other visible solids; removing the macromolecular impurities by ultrafiltration; evaporating and concentrating under reduced pressure conditions; extracting with the water-insoluble extraction after acidification; separating crude crystals of α-KG and crude liquid of PA by evaporation crystallization method (if concentration of PA is great higher than that of α-KG, crystallization separation should be conducted after distilling partial pure pyruvate); washing the crude crystal of α-KG with water-insoluble organic solvent as ethyl acetate or butyl acetate, drying and crushing to obtain qualified α-KG; distilling to gain qualified PA product applying high vacuum distillation (or molecular distillation). 1. A method for extracting alpha-ketoglutarate (α-KG) and pyruvate (PA) simultaneously ,wherein said method comprises:pretreating microbial fermentation broth or enzymatic conversion solution by separating microorganisms and other visible solids from the microbial fermentation broth or enzymatic conversion solution containing α-KG and pyruvate by a centrifugal process, and removing macromolecular impurities though a filtration process, and concentrating α-KG or pyruvate to a concentration of ≥120 g/L, and obtaining a pretreatment solution after crossing the basic ion exchange resin to remove high-valent cations;separating crude α-KG and crude pyruvate by acidifying the pretreatment solution to obtain a acidified solution, and extracting α-KG and pyruvate to obtain an extraction solution from the acidified solution using a water-insoluble extractive agent ...

Behavior Prediction Method and Behavior Prediction Device for Mobile Unit, and Vehicle

A behavior prediction method includes: determining a position of a host vehicle; determining a position of another vehicle in a second travel lane, the second travel lane being an opposite lane to a first travel lane in which the host vehicle travels; detecting an intersecting passage intersecting the second travel lane at a position ahead of the host vehicle; and determining whether or not the another vehicle is located within a predetermined range from an intersection position of the intersecting passage and the second travel lane to a point away from the intersection position by a predetermined distance in an opposite direction to a traveling direction of a vehicle in the second travel lane and the another vehicle is in either state of a stopped state and a decelerated state to predict that there is a probability that a mobile unit enters the first travel lane from the intersecting passage. 1. A behavior prediction method for a mobile unit comprising:determining a position of a host vehicle;determining a position of another vehicle in a second travel lane, the second travel lane being an opposite lane to a first travel lane in which the host vehicle travels;detecting an intersecting passage intersecting the second travel lane at a position ahead of the host vehicle and having an exit from which a vehicle comes out from the outside of the second travel lane, the exit facing the second travel lane;determining whether or not the another vehicle is located within a predetermined range from an intersection position of the intersecting passage and the second travel lane to a point away from the intersection position by a predetermined distance in an opposite direction to a traveling direction of a vehicle in the second travel lane and the another vehicle is in either state of a stopped state and a decelerated state; andwhen the another vehicle is located within the predetermined range and the another vehicle is in the either state of a stopped state and a decelerated ...

Method for Simultaneously Reducing Urethane and its Precursors Levels during Chinese Liquor Production Process

The present invention a method for simultaneously reducing urethane and its precursors levels during Chinese liquor production process, which relates to the field of fermented food production. The present invention is carried out through inoculating JP21 or combines with urease into the grains for fermentation. The content of EC and urea in the fermented grains after 5-day fermentation could reduce 30.16% and 50.05% respectively, With an addition of the during grains fermentation, EC and urea levels are successfully controlled, and at the same time aroma and tastes of Chinese liquor hasn't been affected. 1Bacillus amyloliquefaciensB. amyloliquefaciens. A method for reducing EC and its precursors levels , comprising inoculating 1˜9×10CFU/g () into grains for fermentation.2B. amyloliquefaciens. The method of claim 1 , wherein said is inoculated before grain fermentation begins.3B. amyloliquefaciens. The method of claim 1 , comprising inoculating 5˜10 mL of cell suspension/100 g grains into the grain fermentation.4B. amyloliquefaciensB. amyloliquefaciens. The method of claim 1 , wherein said is JP21 claim 1 , which is deposited in China Center for Type Culture Collection in Wuhan University claim 1 , Wuhan claim 1 , Hubei claim 1 , China on Sep. 19 claim 1 , 2016 with Accession No. CCTCC No: M 2016499.5B. amyloliquefaciens. The method of claim 4 , comprising obtaining the from inoculating into a LB medium and incubating at 37° C. for 24˜48 h.6B. amyloliquefaciens. The method of claim 1 , wherein said is inoculated into grains with urease before the grain fermentation begins.7Lactobacillus reuteri.. The method of claim 6 , wherein said urease is produced from8B. amyloliquefaciensB. amyloliquefaciensB. amyloliquefaciensB. amyloliquefaciens. The method of claim 1 , the method comprising the steps of: 1) collection: inoculating the into LB medium claim 1 , and incubating at 37° C. for 24˜48 h; centrifuging the resulting broth claim 1 , collecting stain precipitation and ...

Digital Image Suitability Determination to Generate AR/VR Digital Content

Techniques image suitability determination to generate augmented reality/virtual reality (AR/VR) digital content are described. A two-dimensional digital image is received. Using machine-learning, a determination as to whether an object captured by the two-dimensional digital image is suitable for generating AR/VR digital content for display in an AR/VR environment is made. If the object is suitable, an indication is provided and an option to view the object in an AR/VR environment is provided. If the object is not suitable, a suggestion indicating why the object as captured is not suitable and/or how to correct the capture of the object in a subsequent digital image such that it is suitable for generating AR/VR digital content.

Traveling Assistance Method of Traveling Assistance Device and Traveling Assistance Device

A traveling assistance method acquires driving characteristics of another vehicle around a host vehicle, determines whether the other vehicle is in an autonomous driving mode depending on the driving characteristics of the other vehicle, and detects an action of the other vehicle in accordance with the determination result of whether the other vehicle is in the autonomous driving mode. 1. A traveling assistance method of a traveling assistance device for detecting an action of another vehicle around a host vehicle to execute traveling assistance to the host vehicle based on the detected action of the other vehicle , the method comprising:acquiring a driving characteristic of the other vehicle;determining whether the other vehicle is in an autonomous driving mode depending on the driving characteristic;setting an intersecting area in which a traveling region of the host vehicle and a traveling region of the other vehicle intersect with each other; anddetecting the action of the other vehicle which enters the intersecting area in accordance with a result of determination of whether the other vehicle is in the autonomous driving mode.2. The traveling assistance method of the traveling assistance device according to claim 1 , further comprising:calculating a difference in reaching time between the host vehicle and the other vehicle traveling toward the intersecting area in which a traveling region of the host vehicle and a traveling region of the other vehicle intersect with each other; anddetecting the action of the other vehicle in accordance with the result of determination of whether the other vehicle is in the autonomous driving mode and the reaching time difference.3. The traveling assistance method of the traveling assistance device according to claim 2 , further comprising detecting a probability that the other vehicle enters the intersecting area prior to the host vehicle in accordance with the result of determination of whether the other vehicle is in the ...

Water level flow speed-increasing generating station, power station, water supply station, and offshore floating city

The present invention relates to the field of hydraulic machinery, and relates to, by using the law of motion conversion and Bernoulli's equation, a generating station formed with a water level speed-increasing water tunnel set on a special ship or offshore floating city increasing a natural flow velocity V1≦1 msec of a water source to a high speed of V2≧200 msec to propel a turbine, and drive a generator; a power station formed with the turbine driving various load machinery; and a water supply station formed with an outlet of the speed-increasing water tunnel being connected to a lift tube. Hence, the present invention can replace high dams of a small number, to convert planar flow dynamics of wide rivers, seas, and oceans into inexhaustible, cheap, clean, and sustainable energy, which is a major theme project of the third industrial revolution.

Automatic determination of radiation beam configurations for patient-specific radiation therapy planning

Systems and methods for efficient and automatic determination of radiation beam configurations for patient-specific radiation therapy planning are disclosed. According to an aspect, a method includes receiving data based on patient information and geometric characterization of one or more organs at risk proximate to a target volume of a patient. The method includes determining automatically one or more radiation treatment beam configuration sets. Further, the method includes presenting the determined one or more radiation beam configuration sets via a user interface.

Methods, Compounds, and Compositions For Treatment and Prophylaxis in the Respiratory Tract

The present invention provides a method of reducing the quantity of mucus in the respiratory tract of a subject with elevated levels of mucus in said respiratory tract. The method includes administering to the subject a compound or composition containing a therapeutically effective amount of a fusion protein comprising a sialidase or an active portion thereof and an anchoring domain. The therapeutically effective amount comprises an amount of the fusion protein that results in a reduction of the quantity of mucus in the respiratory tract after administration of the compound or composition when compared to the quantity of mucus present prior to administration of the compound or composition.

EVENT PROCESSING AND ALLOCATION

Techniques for processing events in a network community are described herein. The disclosed techniques include receiving an event from a user account, the event comprising at least one reason for submitting the event and at least one attribute of content associated with the event; determining whether the event is to be crowd discussed based on at least in part on the at least one reason and the at least one attribute of content; and assigning the event in the crowd discussion list to a zone based at least in part on the at least one attribute of content associated with the event. The event may be a report from the user account. The disclosed techniques further include determining whether the report is to be crowd adjudicated based at least in part on a report weigh value corresponding to the user account and determining whether to allocate any report in the crowd adjudication list to a review account based on a plurality of predetermined rules. 1. A computer-implemented method of processing events , comprising:receiving an event from a first user account, the event comprising information indicative of at least one reason for submitting the event and at least one attribute of content associated with the event;determining whether the event is to be crowd discussed based on at least in part on the information indicative of at least one reason and the at least one attribute of content, wherein the determining whether the event is to be crowd discussed further comprises determining a crowd discussion value of the event by weighing the at least one reason and the at least one attribute of content;in response to a determination that the event is to be crowd discussed, updating a crowd discussion list in an event pool and storing the event in the crowd discussion list; andin response to a determination that the event is not to be crowd discussed, updating a filter or block list in the event pool and storing the event in the crowd filter or block list.2. The computer- ...

IDENTIFICATION OF RULE VIOLATIONS IN A NETWORK COMMUNITY

Techniques for identifying rule violations in a network community are described herein. The disclosed techniques include receiving a report event from a first client computing device, wherein the report event is associated with content and a possible violation and the content comprises one or more comments relative to a plurality of video frames; identifying the content based on the possible violation; sending the content to a plurality of review users, wherein the content is presented and viewable via an interface by each review user; determining whether a voting instruction has been received from each review user during a predetermined period of time; recording a voting instruction from a first review user in a list of voting instructions in response to a determination that the voting instruction has been received during the predetermined period of time; and identifying the possible violation as a violation based on the list of voting instructions. 1. A computer-implemented method of identifying rule violations in a network community comprising a server computing device and a plurality of client computing devices , comprising:receiving, by the server computing device, a report event from a first client computing device among the plurality of client computing devices, wherein the report event is associate with content, a user, and a possible violation of at least one of a set of predefined rules, wherein the content comprises one or more comments relative to a plurality of video frames;identifying, by the server computing device, the content based on the possible violation of the at least one of a set of predefined rules;sending, by the server computing device, the report event and the content to a plurality of review users in the network community, wherein the plurality of review users have been authorized to review report events, wherein the content is presented and viewable via an interface on a display device by each of the plurality of review users, and ...

PERFORMANCE EVALUATION IN A NETWORK COMMUNITY

Techniques for evaluating performance of reviewing events in a network community are described herein. The disclosed techniques include authorizing a first user account to review the events in the network community for a first valid period; monitoring information associated with the first user account reviewing the events in the network community; generating data indicative of review behaviors associated with the first user account during at least a part of the first valid period based at least in part on the information and predetermined parameters of evaluating performance; determining values of a plurality of evaluation coefficients based on the generated data and predetermined rules; and determining a performance evaluation result for the first user account based on the generated data and the values of the plurality of evaluation coefficients. 1. A computer-implemented method for evaluating performance of reviewing events in a network community , comprising:authorizing, by a server, a first user account to review the events in the network community for a first valid period, wherein a first user account is among a plurality of user accounts in the network community;monitoring, by the server, information associated with the first user account reviewing the events in the network community;generating, by the server, data indicative of review behaviors associated with the first user account during at least a part of the first valid period based at least in part on the information and predetermined parameters of evaluating performance of reviewing events in the network community;determining, by the server, values of a plurality of evaluation coefficients based on the generated data and predetermined rules, wherein the predetermined rules comprise corresponding relationships between the generated data and the plurality of evaluation coefficients; anddetermining, by the server, a performance evaluation result for the first user account based on the generated data and ...

Event management and presentation

Techniques for managing and presenting violation events in a network community are described herein. The disclosed techniques include receiving a file containing information indicative of a violation by a user account in the network community who violates community guidelines and storing the file into a violation display pool in response to a determination that a corresponding violation score is greater than a predetermined threshold. The violation display pool comprises a plurality of violation events that each comprise information indicative of a source of a corresponding violation event, at least one attribute of content associated with the corresponding violation event, and information relating to content of the corresponding violation event. A storage server sends the plurality of violation events to a plurality of client computing devices for display via an interface.

FIXING DEVICE FOR WIG AND WIG

A wig includes hairs and the fixing device. The fixing device includes a first soft board, a second soft board and a third soft board. The wig further includes a fixing piece. The fixing piece is connected to the first soft board, and the first soft board is arranged between the fixing piece and the second soft board. The fixing piece includes a frame body, a positioning strip and multiple fastening portions. The positioning strip is connected to the frame body, and the fastening portions are fixedly connected to the frame body. The hairs of the wig are connected to the third soft board or the second soft board, the fixing device is fastened to real hairs of a user, the wig may be smoothly fixed to the real hairs by the user, and the user does not need to customize the wig, a consumption cost is reduced. 1. A fixing device for a wig , wherein the fixing device comprises a first soft board , a second soft board and a third soft board , the first soft board , the second soft board and the third soft board are successively connected;the fixing device further comprises a fixing piece, the fixing piece is connected to the first soft board, and the first soft board is arranged between the fixing piece and the third soft board;the fixing piece comprises a frame body, a positioning strip and multiple fastening portions, the positioning strip is connected to the frame body, and the fastening portions are detachably fixedly connected to the frame body; andthe fastening portion comprises a connecting portion, an abutting portion and a positioning portion, the abutting portion is connected with the connecting portion and the positioning portion, and the connecting portion is detachably fixedly connected to the frame body.2. The fixing device as claimed in claim 1 , wherein:the frame body comprises a first through hole, the frame body is connected to the first soft board through the first through hole.3. The fixing device as claimed in claim 2 , wherein:the frame body comprises ...

TOUCH PANEL AND MANUFACTURING METHOD THEREOF

A touch panel is formed by firstly forming a film layer on a first plate, and next, sequentially forming a buffer layer on the film layer, forming a sensing layer on the buffer layer, forming a second plate on the sensing layer. After the foregoing formation procedures, the first plate is removed from the film layer. Next, a cover is attached to the film layer. In this way, the film layer is located between the cover and the buffer layer. Finally, the second plate is removed from the sensing layer, so as to form a touch panel with the features of light weight, thin thickness and low costs. 1. A touch panel , comprisinga cover;a binding layer;a film layer;a buffer layer;a sensing layer;said binding layer being between said cover and said film layer;said film layer being between said binding layer and said buffer layer;said buffer layer being between said film layer and said sensing layer; andsaid buffer layer comprising an inorganic material and an organic material.2. The touch panel as set forth in claim 1 , comprisingsaid film layer being formed with polyimide (PI).3. The touch panel as set forth in claim 1 , comprisingsaid film layer being formed with a material selected from the group consisting of polypropylene (PP), polystyrene (PS), acrylonitrile-butadiene-styrene (ABS), polyethylene terephthalate (PET), polyvinyl chloride (PVC), polycarbonate (PC), polyethylene (PE), polymethyl methacrylate (PMMA), polytetrafluoro ethylene (PTFE), cyclic olefin copolymer (COP) or a combination thereof.4. The touch panel as set forth in claim 1 , comprisingsaid film layer having a thickness of 0.1 μm to 15 μm.5. The touch panel as set forth in claim 1 , comprisingsaid film layer having a thickness of 2 μm to 5 μm.6. The touch panel as set forth in claim 1 , comprisingsaid inorganic material comprising titanium oxide and silicon oxide.7. The touch panel as set forth in claim 1 , comprisingsaid inorganic material comprising zirconium oxide.8. The touch panel as set forth in ...

Action Prediction Method and Action Prediction Device of Traveling Assistance Device

An action prediction method for predicting an action of another vehicle around a host vehicle, acquires information on conditions of a road surface around the other vehicle, and predicts the action of the other vehicle in accordance with the information on the conditions of the road surface. 1. An action prediction method of a traveling assistance device for assisting a host vehicle in traveling in accordance with a predicted result of an action of another vehicle around the host vehicle , the method comprising:acquiring information of ruts on a road surface around the other vehicle; andpredicting the action of the other vehicle traveling along the ruts in accordance with the information of the ruts on the road surface.2. The action prediction method of the traveling assistance device according to claim 1 , further comprising:determining whether an object is present ahead of the other vehicle in a traveling direction; andpredicting the action of the other vehicle in accordance with the information of the ruts on the road surface and a determination result of a presence or absence of the object.3. (canceled)4. The action prediction method of the traveling assistance device according to claim 1 , wherein the other vehicle is stopping.5. (canceled)6. An action prediction device of a traveling assistance device comprising a controller for predicting an action of another vehicle around a host vehicle in accordance with a position of the other vehicle claim 1 ,the controller being configured to:acquire information of ruts on a road surface around the other vehicle; andpredict the action of the other vehicle traveling along the ruts in accordance with the information of the ruts on the road surface. The present invention relates to an action prediction method and an action prediction device of a traveling assistance device for assisting a host vehicle in traveling in accordance with prediction results of an action of another vehicle around the host vehicle.A vehicle ...

Novel Class of Therapeutic Protein Based Molecules

The present invention provides new compositions and methods for preventing and treating pathogen infection. In particular, the present invention provides compounds having an anchoring domain that anchors the compound to the surface of a target cell, and a therapeutic domain that can act extracellularly to prevent infection of a target cell by a pathogen, such as a virus. The present invention also comprises therapeutic compositions having sialidase activity, including protein-based compounds having sialidase catalytic domains. Compounds of the invention can be used for treating or preventing pathogen infection, and for treating and reducing allergic and inflammatory responses. The invention also provides compositions and methods for enhancing transduction of target cells by recombinant viruses. Such compositions and methods can be used in gene therapy. 1. A fusion protein , comprising at least one catalytic domain of a sialidase and at least one anchoring domain , wherein the catalytic domain sequence comprises:a) the sequence of amino acids extending from amino acid 274 to amino acid 681 of SEQ ID NO:12, inclusive and lacks the sequence that consists of the sequence extending from amino acid 1 to amino acid 273 and from amino acid 682 to amino acid 901 of SEQ ID NO:12;b) the sequence of amino acids extending from amino acid 290 to amino acid 666 of SEQ ID NO:12, inclusive and lacks the sequence that consists of the sequence extending from amino acid 1 to amino acid 289 and from amino acid 667 to amino acid 901 of SEQ ID NO:12; orc) the sequence of amino acids extending from amino acid 290 to amino acid 681 of SEQ ID NO:12, inclusive and lacks the sequence that consists of the sequence extending from amino acid 1 to amino acid 289 and from amino acid 682 to amino acid 901 of SEQ ID NO:12; and the anchoring domain comprises the GAG-binding domain of human platelet factor 4 (SEQ ID NO:2), the GAG-binding domain of human interleukin 8 (SEQ ID NO:3), the GAG-binding ...

1500 MPa GRADE PRESS HARDENING STEEL BY MEDIUM THIN SLAB CASTING AND DIRECT ROLLING AND METHOD FOR PRODUCING THE SAME

A press hardening steel by a medium thin slab and having a tensile strength of 1500 MPa or more, includes following components by weight percent: C: 0.21%-0.25%, Si: 0.26%-0.30%, Mn: 1.0%-1.3%, P≤0.01%, S≤0.005%, Als: 0.015%-0.060%, Cr: 0.25%-0.30%, Ti: 0.026%-0.030% or Nb: 0.026%-0.030% or V: 0.026%-0.030% or a mixture of any two or more of the above in any proportion, B: 0.003%-0.004%, Mo: 0.17-0.19% and N≤0.005%. A method for producing the press hardening steel includes following steps: molten iron desulphurization; smelting and refining by an electric furnace or converter; continuous casting; descaling treatment before entering a soaking furnace; hating and soaking; high pressure water descaling before entering a rolling mill; hot rolling; cooling; coiling; austenitizing; die deforming and quenching. 1. A press hardening steel , produced by a medium and thin slab casting and direct rolling and having a tensile strength of 1500 MPa or more , the press hardening steel comprising following components by weight percent: C: 0.21%-0.25% , Si: 0.26%-0.30% , Mn: 1.0%-1.3% , P≤0.01% , S≤0.005% , Als: 0.015%-0.060% , Cr: 0.25%-0.30% , Ti: 0.026%-0.030% or Nb: 0.026%-0.030% or V: 0.026%-0.030% or a mixture of any two or more of the above in any proportion , B: 0.003%-0.004% , Mo: 0.17-0.19% , N≤0.005% , and a balance of Fe and inevitable impurities.2. A method for producing the press hardening steel according to claim 1 , the method comprising following steps:1) desulphurizing molten iron, and controlling S to be smaller or equal to 0.002%, an exposed surface of the molten iron after slagging off being not lower than 96%;2) performing conventional electric furnace or converter smelting, and conventional refining;3) performing continuous casting, and controlling a degree of superheat of tundish molten steel to be 15° C. to 30° C., a thickness of a slab to be 61 mm to 150 mm, and a casting speed to be 2.8 m/min to 5.5 m/min;4) performing descaling treatment before the slab ...

1900 MPa GRADE PRESS HARDENING STEEL BY THIN SLAB CASTING AND DIRECTLY ROLLING AND METHOD FOR PRODUCING THE SAME

A press hardening steel by a thin slab and having a tensile strength of 1900 MPa or more includes following components by weight: C: 0.31-0.40%, Si: 0.36-0.44%, Mn: 1.6-2.0%, P≤0.006%, S≤0.004%, Als: 0.015-0.060%, Cr: 0.36-0.49%, Ti: 0.036-0.045% or Nb: 0.036-0.045% or V: 0.036-0.045% or a mixture of any two or more of the above in any proportion, B: 0.004-0.005%, Mo: 0.26-0.35%, and N≤0.005%. A method for producing the press hardening steel includes following steps: molten iron desulphurization; smelting and refining by an electric furnace or converter; continuous casting; descaling treatment before entering a soaking furnace; heating and soaking; high pressure water descaling before entering a rolling mill; hot rolling; cooling; coiling; austenitizing; die deforming and quenching. 1. A press hardening steel , produced by a thin slab casting and direct rolling and having a tensile strength of 1900 MPa or more , the press hardening steel comprising following components by weight percent: C: 0.31-0.40% , Si: 0.36-0.44% , Mn: 1.6-2.0% , P≤0.006% , S≤0.004% , Als: 0.015-0.060% , Cr: 0.36-0.49% , Ti: 0.036-0.045% or Nb: 0.036-0.045% or V: 0.036-0.045% or a mixture of any two or more of the above in any proportion , B: 0.004-0.005% , Mo: 0.26-0.35% , and N≤0.005% , and a balance of Fe and inevitable impurities , wherein a quenched microstructure is a full lath martensite; and mechanical properties are that a yield strength greater than or equal to 1300 MPa , tensile strength greater than or equal to 1900 MPa , and elongation Agreater than or equal to 5%.2. A method for producing the press hardening steel according to claim 1 , the method comprising following steps:1) desulphurizing molten iron, and controlling S to be smaller or equal to 0.002%, an exposed surface of the molten iron after slagging off being not lower than 96%;2) performing conventional electric furnace or converter smelting, and conventional refining;3) performing continuous casting, and controlling a ...

SEARCH INFORMATION PROCESSING METHOD AND APPARATUS

Methods, systems, and apparatus, including computer programs encoded on computer storage media, for processing search information. One of the methods includes receiving search information from a user and sending the search information to a cloud server to cause the cloud server to perform search processing based on the search information. The method further includes pushing display information to the user on a display interface before the cloud server returns a result associated with the search processing. 1. A search information processing method , comprising:receiving search information from a user;sending the search information to a cloud server to cause the cloud server to perform search processing based on the search information; andbefore the cloud server returns a result associated with the search processing, pushing display information to the user on a display interface.2. The method of claim 1 , wherein the display information comprises at least one of the following:a picture, audio, a video, an animation, and text.3. The method of claim 1 , wherein the display information comprises:information satisfying a setting by the user; or information associated with the search information.4. The method of claim 3 , wherein the setting comprises:a setting on a display form of the display information; ora setting on information content of the display information.5. The method of claim 3 , wherein the information associated with the search information comprises:information associated with a type of the search information; orinformation associated with content of the search information.6. The method of claim 1 , wherein the pushing comprises:obtaining the display information from a preset local storage; andpushing the display information to the user.7. The method of claim 1 , wherein the pushing comprises:receiving the display information from the cloud server according to a setting by the user; andpushing the display information to the user.8. The method of claim 7 , ...

Vehicle Control Method and Vehicle Control Device

A vehicle control method includes: detecting a blocking object that is at a position at which the blocking object obstructs travel of the tracked vehicle in a traffic lane in which the tracked vehicle is traveling and that hides at least part of the traffic lane from the sensor, and an oncoming vehicle traveling in a direction toward the tracked vehicle in an oncoming lane opposite from the traffic lane; and slowing down the vehicle when the oncoming vehicle slows down. 1. A vehicle control method using a sensor detecting position information on an object around a vehicle and a control circuit controlling the vehicle according to a tracked vehicle detected based on the position information , the method comprising:detecting, by the control circuit, a blocking object that is at a position at which the blocking object obstructs travel of the tracked vehicle in a traffic lane in which the tracked vehicle is traveling and that hides at least part of the traffic lane from the sensor, and an oncoming vehicle traveling in a direction toward the tracked vehicle in an oncoming lane opposite from the traffic lane; andslowing down the vehicle by the control circuit when the oncoming vehicle slows down.2. The vehicle control method according to claim 1 , whereinthe control circuit estimates passing time until the tracked vehicle passes through an area hidden by the blocking object, based on speed of the oncoming vehicle and distance from the oncoming vehicle to the blocking object, andthe control circuit slows down the vehicle when the oncoming vehicle slows down and the passing time is shorter a specified threshold.3. The vehicle control method according to claim 1 , whereinthe control circuit estimates arrival time after the tracked vehicle passes by the blocking object until the tracked vehicle reaches a front of the vehicle, based on speed of the oncoming vehicle and distance from the front of the vehicle to the blocking object, andthe control circuit sets stop time for the ...

Technology for Preparation of Macromolecular Microspheres

Microspheres are produced by contacting an aqueous solution of a protein or other macromolecule with an organic solvent and a counterion, and chilling the solution. The microspheres are useful for preparing pharmaceuticals of defined dimensions.

HUMANIZED ANTIBODIES

Humanized antibodies that bind ICAM-1 are provided. Antibodies include those selected from: SEQ ID NO:1 and 3 (HumA); SEQ ID NO:5 and 7 (HumB); SEQ ID NO:9 and 11 (HumC); SEQ ID NO:13 and 15 (HumD); SEQ ID NO:17 and 19 (HumE); SEQ ID NO:21 and 23 (HumF); SEQ ID NO:25 and 27 (HumG); SEQ ID NO:29 and 31 (HumH); and SEQ ID NO:33 and 35 (HumI). Subsequences of the humanized antibodies capable of finding an ICAM-1 epitope are also provided. Methods of inhibiting pathogen infection (e.g., HRV) of a cell employing humanized antibodies capable of finding an ICAM-1 epitope are further provided. 1. An antibody that binds ICAM-1 comprising:{'sub': 'H', 'i) a Vregion having at least 60% sequence homology to SEQ ID NO: 9, or'}{'sub': 'L', 'ii) a Vregion having at least 60% sequence homology to SEQ ID NO: 11.'}2. The antibody or antibody subsequence of having a protective efficacy against pathogen infection greater than an antibody having mouse monoclonal antibody 1A6 variable domains.3. The antibody of having a binding affinity for ICAM-1 greater than an antibody having mouse monoclonal antibody 1A6 variable domains.4. The antibody of claim 2 , wherein said pathogen is human rhinovirus (HRV) claim 2 , coxackie A virus claim 2 , respiratory syncytial virus (RSV) or malaria.5. The antibody of claim 1 , wherein said antibody or antibody subsequence is linked to one or more identical or different antibodies to form a multimeric antibody complex.6. The antibody of claim 5 , wherein said multimeric complex is formed via a multimerization domain.7. The antibody of claim 6 , further comprising a linker between said t multimerization domain and said antibody.8. The antibody of claim 5 , wherein said multimeric complex is a homo- or hetero-dimer claim 5 , trimer claim 5 , tetramer or pentamer.9. The antibody of claim 1 , wherein said antibody or antibody subsequence has 1-10 amino acid substitutions.10. The antibody of claim 9 , wherein said substitutions are conservative substitutions.11 ...

Methods, Compounds, and Compositions For Treatment and Prophylaxis in the Respiratory Tract

The present invention provides a method of reducing the quantity of mucus in the respiratory tract of a subject with elevated levels of mucus in said respiratory tract. The method includes administering to the subject a compound or composition containing a therapeutically effective amount of a fusion protein comprising a sialidase or an active portion thereof and an anchoring domain. The therapeutically effective amount comprises an amount of the fusion protein that results in a reduction of the quantity of mucus in the respiratory tract after administration of the compound or composition when compared to the quantity of mucus present prior to administration of the compound or composition. 1. A method of reducing the quantity or level of mucus or preventing an increase in the quantity or level of mucus in a respiratory tract of a subject , the method comprising:administering to the subject a compound or composition comprising a therapeutically effective amount of a fusion protein, whereinthe fusion protein comprises at least one catalytic domain of a sialidase, wherein the catalytic domain of the sialidase comprises the sequence of amino acids extending from amino acid 274 to amino acid 666 of SEQ ID NO:12, inclusive, and at least one anchoring domain, wherein the anchoring domain is a glycosaminoglycan (GAG) binding domain of human amphiregulin comprising the amino acid sequence of SEQ ID NO:7; andthe therapeutically effective amount comprises an amount of the fusion protein that results in a reduction of the quantity of mucus in the respiratory tract after administration of the compound or composition when compared to the quantity of mucus present prior to administration of the compound or composition.2. The method of claim 1 , wherein the composition further comprises one or more additional compounds.3. The method of claim 2 , wherein the one or more additional compounds comprises MgSOor an analog thereof.4. The method of claim 2 , wherein the one or more ...

Object Detection Method and Object Detection Apparatus

An object detection method includes: acquiring three-dimensional data on an area around a host vehicle by use of a distance measurement sensor; based on map data on an area around a current position of the host vehicle, setting a planned travel area where the host vehicle is going to travel in the future; estimating crossing object existence areas where there currently exist objects which are likely to cross the host vehicle in the future in the set planned travel area; and detecting the object by use of the three dimensional data on insides of the estimated crossing object existence areas. 1. An object detection method for an object detection apparatus including a distance measurement sensor for acquiring three-dimensional data on an area around a host vehicle , and configured to detect an object by use of the three-dimensional data acquired by the distance measurement sensor , comprising:based on map data on an area around a current position of the host vehicle, extracting a vehicle traffic lane which the host vehicle is estimated to travel on a planned travel route from the current position of the host vehicle to a destination as a planned travel area,based on road structure information included in the map data, estimating road categories whose traveling directions point to the planned travel area as crossing object existence areas where there currently exist objects which are likely to cross the host vehicle in the future in the planned travel area,detecting the road categories around the current position of the host vehicle from the road structure information, extracting the crossing object existence areas by extracting the road categories which cross the planned travel area from the detected road categories, anddetecting the object by use of the three-dimensional data on insides of the crossing object existence areas.2. The object detection method according to claim 1 , wherein the planned travel area is set based on travel plan information of the host vehicle ...

Step Detection Device and Step Detection Method

A step detection device detects the distance and the direction to a road surface around a vehicle, using a distance sensor mounted on the vehicle, and sets a first step determination position and a second step determination position on the road surface. Then, the step detection device calculates the height changes of the road surfaces at the first step determination position and the second step determination position based on the distance and the direction to the road surface, and detects a step on the road surface based on one of the step determination positions, the gradient of the height change of the road surface at the one being larger.

Technology for the Preparation of Microparticles

Microspheres are produced by contacting a solution of a macromolecule or small molecule in a solvent with an antisolvent and a counterion, and chilling the solution. The microspheres are useful for preparing pharmaceuticals, nutraceuticals, cosmetic products and the like of defined dimensions. 1a) adding a counterion to a solution containing the compound in a solvent;b) adding an antisolvent to the solution; andc) gradually cooling the solution to a temperature below about 25° C., whereby a composition containing microparticles comprising the compound is formed, wherein steps a), b) and c) are performed simultaneously, sequentially, intermittently, or in any order.. A method of making microparticles of a compound, comprising: This application is a continuation and claims priority to U.S. application Ser. No. 14/742,612, filed Jun. 17, 2015, which claims prioritiy to U.S. application Ser. No. 14/341,502, filed Jul. 25, 2014, which claims priority to U.S. application Ser. No. 13/874,424, filed Apr. 30, 2013, which claims priority to U.S. application Ser. No. 13/250,653, filed Sep. 30, 2011, which claims priority to U.S. application Ser. No. 12/179,520, filed Jul. 24, 2008, which claims priority to U.S. provisional application Ser. No. 60/961,872, entitled “TECHNOLOGY FOR THE PREPARATION OF MICROPARTICLES” to Fang et al. filed Jul. 24, 2007. This application also is related to International PCT Application No. (Attorney Dkt. No. 21865-005WO1/6505PC) filed on the same day herewith. Each of these applications is incorporated by reference herein in its entirety.This application is related to International PCT Application Serial No. (Attorney Docket No. 21865-004WO1/6504PC, filed Jan. 24, 2007), and to U.S. application Ser. No. 11/657,812, filed Jan. 24, 2007 (Attorney Docket No. 21865-004001/6504). This application also is related to published U.S. applications Serial Nos. US20050004020 A1 and US20050112751 A1. Each of these applications is incorporated by reference ...

Tuning optoelectronic transceivers in optical network

A method of tuning optoelectronic transceivers in an optical network may include powering on an optoelectronic transceiver, setting the channel wavelength of the optoelectronic transceiver, transmitting a request command from the optoelectronic transceiver through the optical network to another optoelectronic transceiver; and waiting to receive a second request command from the another optoelectronic transceiver.

Bidirectional optical communication with minimal guard band

A module, system and method adjusts a tunable filter to have an adjustable frequency response based on one of an outbound optical signal on a transmit channel and an inbound optical signal on a receive channel. The tunable filter is in an optical path of the outbound optical signal and in an optical path of the inbound optical signal. The transmit and the receive channels are configured as part of a channel plan of a bidirectional (bi-di) dense wavelength division multiplexing (DWDM) system.

Novel Class of Therapeutic Protein Based Molecules

The present invention provides new compositions and methods for preventing and treating pathogen infection. In particular, the present invention provides compounds having an anchoring domain that anchors the compound to the surface of a target cell, and a therapeutic domain that can act extracellularly to prevent infection of a target cell by a pathogen, such as a virus. The present invention also comprises therapeutic compositions having sialidase activity, including protein-based compounds having sialidase catalytic domains. Compounds of the invention can be used for treating or preventing pathogen infection, and for treating and reducing allergic and inflammatory responses. The invention also provides compositions and methods for enhancing transduction of target cells by recombinant viruses. Such compositions and methods can be used in gene therapy.

FOUR-DIMENSIONAL IMAGING METHOD FOR STRUCTURAL DAMAGE BASED ON TIME-INVARIANT CHARACTERISTIC SIGNAL

The present disclosure provides a four-dimensional imaging method for structural damage based on a time-invariant characteristic signal. The method first uses a probability statistical modeling method to describe the uncertainty distribution of the amplitude of each sampling point in the signal in the healthy state and the damaged state of the structure, respectively. Then the degree of difference between the two distributions at each point is measured to suppress the influence of the time-varying factor, highlight the influence of damage, and construct a time-invariant characteristic signal. Finally, the time-invariant characteristic signal of the pitch-catch channel is fused by using the guided wave imaging method to further enhance the influence of damage. Based on this, four-dimensional imaging is performed to achieve reliable and accurate location of structural damage. The present disclosure solves the problem that the conventional method is difficult to perform reliable damage diagnosis under time-varying service conditions. 1. A four-dimensional imaging method for structural damage based on a time-invariant characteristic signal , comprising:constructing a time-invariant characteristic signal: describing an uncertainty distribution of an amplitude of each sampling point in a guided wave signal under an influence of a time-varying factor by using a probabilistic statistical modeling method, updating a model and quantifying a migration degree of the model during a monitoring process, so as to suppress an influence of the time-varying factor and highlight an influence of damage, obtaining a time-invariant description of the amplitude of each sampling point, and smooth filtering the time-invariant description of the amplitude of all of the sampling points based on a continuous complex wavelet transform to construct the time-invariant characteristic signal; andfour-dimensional imaging damage: fusing a time-invariant characteristic signal of each pitch-catch ...

Object Tracking Method and Object Tracking Device

An object tracking device tracks objects in a time series using an object detection sensor for detecting objects around a host vehicle. When a plurality of objects are detected, the object tracking device sorts the objects into groups in accordance with a degree of influence of the positions of the objects on the movement of the host vehicle. The object tracking device tracks each of the groups as a single object in a time series. 1. An object tracking method of tracking objects in a time series using a sensor for detecting the objects around a host vehicle , the method comprising:when a plurality of objects are detected, sorting the objects into groups in accordance with a degree of influence of positional relationship between the host vehicle and the objects on a movement of the host vehicle; andtracking each of the groups as a single object in a time series.2. The object tracking method according to claim 1 , wherein claim 1 , as the degree of influence of the positional relationship between the host vehicle and the objects on the movement of the host vehicle is smaller claim 1 , the objects located in a wider region are sorted into a single group.3. The object tracking method according to claim 2 , wherein claim 2 , as the positions of the objects are farther from a traveling route of the host vehicle claim 2 , the degree of influence on the movement of the host vehicle is determined to be smaller.4. The object tracking method according to claim 2 , wherein claim 2 , as the positions of the objects are farther from the host vehicle claim 2 , the degree of influence on the movement of the host vehicle is determined to be smaller.5. The object tracking method according to claim 1 , wherein claim 1 , when the plurality of objects are detected claim 1 , the objects are sorted into groups in accordance with the degree of influence of the positional relationship between the host vehicle and the objects on the movement of the host vehicle and a moving amount of the ...

Object Tracking Method and Object Tracking Apparatus

In a case where multiple objects detected by an object detector enter a hidden area calculated by a hidden area calculator, a positional relationship estimator estimates a positional relationship between the multiple objects in the hidden area based on: information about each of the multiple objects; and lanes and routes into which each of the multiple objects may change their courses, and which are calculated by a route calculator. When the objects come out of the hidden area, an identification number assigner determines identification information about each object based on the positional relationship estimated by the positional relationship estimator. 1. An object tracking method for an object tracking apparatus which includes a sensor for detecting an object around a moving body , and a controller for tracking the object based on a result of detecting the object , the object tracking method comprising:in a case where a plurality of the objects enter a hidden area within a detection range of the sensor, estimating a positional relationship between the plurality of the objects in the hidden area; andwhen the objects come out of the hidden area, determining identification information about each object based on the estimated positional relationship.2. The object tracking method according to claim 1 , wherein in a case where the positional relationship between the plurality of the objects in the hidden area can be estimated claim 1 , the identification information determined for each object before the object enters the hidden area continues being assigned to the object when the object comes out of the hidden area.3. The object tracking method according to claim 1 , wherein in a case where the positional relationship between the plurality of the objects in the hidden area cannot be estimated claim 1 , each object is assigned new identification information when the object comes out of the hidden area.4. The object tracking method according to claim 3 , wherein in a case ...

ECOTIN VARIANTS

Ecotin variants and their use in treating viral hemorrhagic fever are described. Described herein are methods for treating systemic inflammatory response syndrome or viral hemorrahagic fever by administering an ecotin polypeptide. Described herein is a polypeptide comprising the amino acid sequence of any of SEQ ID NOs: 2-9 and 11-18. Also described: is a polypeptide comprising the amino acid sequence of any of SEQ ID NO: 11-18 preceded by a methionine; a polypeptide comprising the amino acid sequence of any of SEQ ID NO: 11 -18 with up to 5 single amino acid changes or deletions provided that the polypeptide does not comprise the amino acid sequence of SEQ ID NO: 10. 1. A polypeptide comprising the amino acid sequence of any of SEQ ID NOs: 2-9 and 11-18.2. A polypeptide comprising the amino acid sequence of any of SEQ ID NO:11-18 preceded by a methionine.3. A pharmaceutical composition comprising a polypeptide of and a pharmaceutically acceptable carrier or excipient.4. A method for treating a patient infected with a microorganism that causes viral hemorrhagic fever claim 3 , the method comprising administering the pharmaceutical composition of .5. The method of wherein the patient is infected with a virus from a family selected from the group consisting of: Filoviridae claim 4 , Bunyaviridae claim 4 , Flaviviridae claim 4 , and Arenaviridae.6. The method of wherein the patient is infected with a virus selected from Ebola virus (EBOV) claim 5 , Marburg Virus (MARV) claim 5 , Rift Valley Fever virus (RVFV) claim 5 , Hantaviruses claim 5 , and Dengue virus.7. A polypeptide comprising the amino acid sequence of any of SEQ ID NO:2-9 and 11-18 with up to 5 single amino acid changes or deletions provided that the polypeptide does not comprise the amino acid sequence of SEQ ID NO:1 or 108. The polypeptide of having up to 3 single amino acid changes provided that the polypeptide does not comprise the amino acid sequence of SEQ ID NO:1 or 109. The polypeptide of having up ...

Digital Image Suitability Determination to Generate AR/VR Digital Content

Techniques image suitability determination to generate augmented reality/virtual reality (AR/VR) digital content are described. A two-dimensional digital image is received. Using machine-learning, a determination as to whether an object captured by the two-dimensional digital image is suitable for generating AR/VR digital content for display in an AR/VR environment is made. If the object is suitable, an indication is provided and an option to view the object in an AR/VR environment is provided. If the object is not suitable, a suggestion indicating why the object as captured is not suitable and/or how to correct the capture of the object in a subsequent digital image such that it is suitable for generating AR/VR digital content. 1. A method implemented by a computing device , the method comprising:receiving, by the computing device, a two-dimensional digital image;generating, by the computing device, a suggestion indicating why an object captured by the two-dimensional digital image is not suitable for generating augmented reality/virtual reality (AR/VR) digital content for display in an AR/VR environment, the generating performed using a machine-learning model;autocorrecting, by the computing device, a subsequent two-dimensional digital image based on the suggestion; andoutputting, by the computing device, the autocorrected subsequent two-dimensional digital image.2. The method as described in claim 1 , further comprising outputting the suggestion for display in a user interface claim 1 , the suggestion indicating that the two-dimensional digital image is not suitable for generating augmented reality/virtual reality (AR/VR) digital content.3. The method as described in claim 2 , wherein the suggestion includes an option that is user selectable to initiate the autocorrecting of the subsequent two-dimensional digital image.4. The method as described in claim 1 , wherein the autocorrecting is performed automatically and without user intervention as part of capturing ...

Method for Reducing the Precursor of Ethyl Carbamate in Soy Sauce

The present invention provides a method for reducing EC precursor, citrulline, in soy sauce by inoculating BBE R23 during soy sauce fermentation. Compared to the control, citrulline and EC in soy sauce prepared with BBE R23 is decreased by 86% and 50%, respectively. Addition of 10CFU/mL BBE R23 also increases volatile flavoring compounds and free fatty acids concentration in the soy sauce product. The present invention provides a method of making soy sauce that not only reduces accumulation of EC precursor citrulline but also improves soy sauce flavor. 1Tetragenococcus halophilusT. halophilus. A method for reducing a precursor of ethyl carbamate in a soy sauce product , comprising artificially inoculating () during soy sauce fermentation.2. The method of claim 1 , wherein said precursor of ethyl carbamate is citrulline.3T. halophilusTetragenococcus halophilus. The method of claim 1 , wherein said is BBE R23 which was conserved in China Center for Type Culture Collection on Oct. 20 claim 1 , 2013 with an accession No. of CCTCC NO: M 2013480.4T. halophilus. The method of claim 1 , wherein said is inoculated into the soy sauce fermentation when koji is mixed with salted water.5T. halophilus. The method of claim 1 , the inoculation amount of is 10˜10CFU/mL.6T. halophilus. The method of claim 4 , the inoculation amount of is 10˜10CFU/mL.7T. halophilus. The method of claim 1 , the inoculation amount of is 10CFU/mL.8T. halophilus. The method of claim 4 , the inoculation amount of is 10CFU/mL.9. The method of claim 1 , further comprising the steps for preparation of koji:1), soaking defatted soybean and parched wheat in water for 8 hours, and sterilizing at 121° C. for 8 minutes;{'i': 'Aspergillus oryzae', '2), mixing the soaked soybean, parched wheat, bran and flour according to a mass ratio of (15-25):(10-20):1:1, and inoculating the mixture with spore to obtain a preliminary koji; and'}3) fermenting until the color of the preliminary koji turned light green to obtain a ...

1,4-DIHYDRO-NAPHTHYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION AND USE THEREOF

Disclosed are 1,4-dihydro-naphthyridine derivatives and pharmaceutical composition and uses thereof. The 1,4-dihydro-naphthyridine derivatives are a compound capable of inhibiting acetylcholinesterase activity and preventing extracellular calcium from flowing into a cell via a calcium channel, i.e., having a dual-activity, which are of potential importance as a pharmaceutical and can be used to prepare the drugs for treating cardiovascular diseases, cerebrovascular diseases and dementia. 2. The compound or pharmaceutically acceptable salts thereof according to claim 1 , characterized in that:{'sub': 1', '8', '3', '8', '2', '8', '2', '8', '2', '1', '8', '3', '8', '2', '8', '2', '8', '2', '6', '1', '8', '3', '8', '2', '8', '2', '8', '4', '5, 'wherein R is selected from the group consisting of aryl and heteroaryl, and said aryl or heteroaryl is optionally substituted at any position on the ring by halogen atom, amino, nitro, cyano, trihaloalkyl, acyl, alkoxyl, aryl, heteroaryl, heteroalicyclic group, C-Calkyl, C-Ccycloalkyl, C-Calkenyl or C-Calkynyl, wherein the substituents on any two optional positions can be combined to form aliphatic ring, heterocyclic ring, aromatic ring or heteroaromatic ring, and optional —CH— on said C-Calkyl, C-Ccycloalkyl, C-Calkenyl or C-Calkynyl can be replaced by one or two or more of —O—, —S—, —SO—, —C(O)— or/and —NR—, and said C-Calkyl, C-Ccycloalkyl, C-Calkenyl or C-Calkynyl can be substituted at optional position by one or two or more of halogen atom, cyano, amino, hydroxyl and —NRR;'}{'sub': '7', 'X is selected from the group consisting of —O— and —NR—;'}{'sub': 4', '5', '1', '8', '3', '8', '4', '5, 'Rand Rare independently selected from the group consisting of hydrogen, aryl, heteroaryl, C-Calkyl, C-Ccycloalkyl, or Rand Rare combined to form a heteroalicyclic group;'}{'sub': 6', '1', '8', '3', '8, 'Ris selected from the group consisting of hydrogen, aryl, heteroaryl, C-Calkyl and C-Ccycloalkyl;'}{'sub': 7', '1', '8', '3', '8, 'Ris ...

Bidirectional communication module

In an example, a communication module includes an optical transmitter, an optical receiver, and a periodical filter. The optical transmitter is configured to emit an outbound optical signal. The optical receiver is configured to receive an inbound optical signal. A first frequency of the outbound optical signal is offset from a second frequency of the inbound optical signal by an amount less than a channel spacing of a multiplexer/demultiplexer implemented in an optical communication system that includes the communication module. The periodical filter is positioned in optical paths of both the outbound optical signal and the inbound optical signal and has a transmission spectrum with periodic transmission peaks and troughs. The first frequency of the outbound optical signal may be aligned to one of the transmission peaks and the second frequency of the inbound optical signal may be aligned to one of the transmission troughs, or vice versa.

TECHNOLOGY FOR PREPARATION OF MACROMOLECULAR MICROSPHERES

Microspheres are produced by contacting an aqueous solution of a protein or other macromolecule with an organic solvent and a counterion, and chilling the solution. The microspheres are useful for preparing pharmaceuticals of defined dimensions. 1. A method of making a protein-based composition , comprising:a) adding a counterion to a solution containing the protein in an aqueous solvent;b) adding an organic solvent to the solution; andc) gradually cooling the solution to a temperature below about 25° C., whereby a composition containing microparticles comprising the protein is formed, wherein steps a), b) and c) are performed simultaneously, sequentially, intermittently, or in any order.2141.-. (canceled) This application is a continuation of U.S. application Ser. No. 14/148,543, filed Jan. 6, 2014, which is a continuation of U.S. application Ser. No. 13/289,644, filed Nov. 4, 2011, which is a continuation of U.S. application Ser. No. 12/633,773, filed Dec. 8, 2009, which is a continuation of U.S. application Ser. No. 11/657,812, filed Jan. 24, 2007, which claims priority to U.S. Provisional Application No. 60/762,002, filed Jan. 24, 2006, all of which are hereby incorporated by reference in its entirety.This application also is related to International PCT application application Serial No. (Attorney Docket No. 21865-004WO1/6504PC, filed Jan. 24, 2007). This application also is related to published U.S. applications Serial Nos. US20050004020 A1 and US20050112751 A1. Each of these applications is incorporated by reference in its entirety.The administration of proteins to animals, including humans, in nutritional supplements or as therapeutics has been known for some time. Proteins for therapeutic or nutritional administration generally are available either as (1) concentrates or powders that are administered directly or are reconstituted in a liquid of choice prior to use; or (2) liquid formulations.The preparation and delivery of therapeutic proteins of interest ...

MULTI-PROFILE TRACKING IDENTIFICATION OF A MOBILE USER

Embodiments are directed towards employing multiple profiles to track identification of users across multiple domains. Multiple application-domain profiles and multiple web-domain profiles may each include a statistical identifier. A profile enrichment store may be generated from the application-domain profiles and web-domain profiles, where each entry in the profile enrichment store may be based on statistical identifiers. The profile enrichment store may be utilized to determine categories associated with a statistical identifier for a request from a client device. A targeted advertisement may be determined based on the determined category and may be provided to the client device. A client caching identifier may be used in a mobile web domain, in combination with the statistical identifier, to track mobile web users. If a request is associated with a profile that includes an affirmative opt-out flag, categories in the profile enrichment store for a corresponding statistical identifier may be cleaned up. 1. A method for tracking user profiles over a network , wherein at least one network device enables actions to be performed , comprising:providing a plurality of application domain profiles and a plurality of web domain profiles, wherein each of the application domain profiles and each of the web domain profiles includes at least a statistical identifier, and wherein the plurality of application domain profiles are not provided by a web browser;generating, by the at least one network device, a profile enrichment store from the plurality of application domain profiles and the plurality of web domain profiles based on at least the associated statistical identifiers for each profile, wherein each entry in the profile enrichment store includes a different statistical identifier that non-uniquely identifies each of a plurality of client devices and each entry includes at least one category associated with at least one of the plurality of application domain profiles or ...

CLIENT CACHING IDENTIFICATION TRACKING

Embodiments are directed towards employing multiple profiles to track identification of users across multiple domains. Multiple application-domain profiles and multiple web-domain profiles may each include a statistical identifier. A profile enrichment store may be generated from the application-domain profiles and web-domain profiles, where each entry in the profile enrichment store may be based on statistical identifiers. The profile enrichment store may be utilized to determine categories associated with a statistical identifier for a request from a client device. A targeted advertisement may be determined based on the determined category and may be provided to the client device. A client caching identifier may be used in a mobile web domain, in combination with the statistical identifier, to track mobile web users. If a request is associated with a profile that includes an affirmative opt-out flag, categories in the profile enrichment store for a corresponding statistical identifier may be cleaned up. 1. A method for tracking user profiles over a network , wherein at least one network device enables actions to be performed , comprising:receiving a content request from a client device;determining, by the at least one network device, a statistical identifier associated with the client device,if the content request fails to include a previously provided client caching identifier, generating a new client caching identifier for the client device, wherein the client device caches the new generated client caching identifier;generating a profile identifier using the client caching identifier and the statistical identifier, wherein the profile identifier is associated with no fewer than a predetermined number of client devices, the predetermined number of client devices based at least in part on a predetermined constraint set by an advertising industry standard or a regulatory standard;storing a profile for the client device based on the generated profile identifier; ...

TOUCH PANEL AND DIRECT PATTERNING METHOD THEREOF

The direct patterning method includes: providing a substrate having a display area and a peripheral area, which a peripheral circuit having a bonding pad is disposed on the peripheral area; sequentially disposing a metal nanowire layer, a pre-cured film layer and a negative-type photosensitive layer thereon; performing a photolithography step; and curing the pre-cured film layer. The photolithography step includes exposing the negative-type photosensitive layer to define a removal region and a reserved region; and removing the negative-type photosensitive layer, the pre-cured film layer and the metal nanowire layer in the removal region by using a developer, such that a touch sensing electrode is fabricated in the display area and the bonding pad is exposed. 1. A direct patterning method for forming a touch panel , comprising:providing a substrate having a display area and a peripheral area, wherein a peripheral circuit is disposed in the peripheral area, and the peripheral circuit comprises a bonding pad;disposing a metal nanowire layer in the display area and the peripheral area, wherein the metal nanowire layer comprises a plurality of metal nanowires;pre-curing a material as a pre-cured film layer on the metal nanowire layer;disposing a negative-type photosensitive layer on the pre-cured film layer; exposing the negative-type photosensitive layer to define a removal region and a reserved region; and', 'removing the negative-type photosensitive layer, the pre-cured film layer and the metal nanowire layer in the removal region by using a developer solution, such that a touch sensing electrode electrically connected to the peripheral circuit is fabricated on the display area, and the bonding pad in the peripheral area is exposed, wherein the touch sensing electrode comprises the pre-cured film layer and the metal nanowire layer, and wherein the pre-cured film layer and the metal nanowire layer in the reserved region are covered by the negative-type photosensitive ...

Inter-Vehicle Distance Estimation Method and Inter-Vehicle Distance Estimation Device

An inter-vehicle distance estimation method includes: estimating a screened area screened by an obstacle from a sensor and two unscreened areas sandwiching the screened area; and, based on speeds of two tracked vehicles traveling in a same traffic lane respectively within the two unscreened areas, estimating the inter-vehicle distances from the two tracked vehicles to a tracked vehicle traveling in the same traffic lane within the screened area. 1. An inter-vehicle distance estimation method using a sensor that detects positional information of objects around a vehicle , and a processing circuit that estimates inter-vehicle distances between a plurality of tracked vehicles detected based on the positional information , comprising:causing the processing circuit to estimate a screened area screened by an obstacle from the sensor and two unscreened areas sandwiching the screened area; andcausing the processing circuit to, based on speeds of two of the tracked vehicles traveling in a same traffic lane respectively within the two unscreened areas, estimate the inter-vehicle distances from the two tracked vehicles to one of the tracked vehicles traveling in the same traffic lane within the screened area.2. The inter-vehicle distance estimation method according to claim 1 , further comprising:causing the processing circuit to estimate a speed of the tracked vehicle traveling in the same traffic lane within the screened area; andcausing the processing circuit to estimate the inter-vehicle distances based on the estimated speed of the tracked vehicle.3. The inter-vehicle distance estimation method according to claim 1 , further comprising:causing the processing circuit to estimate, in map data, a travel area in which the plurality of tracked vehicles travel; andcausing the processing circuit to estimate the two unscreened areas within the travel area.4. The inter-vehicle distance estimation method according to claim 1 , further comprising:causing the sensor to detect at ...

METHOD AND APPARATUS FOR VISUALIZATION OF PUBLIC WELFARE ACTIVITIES

A method for implementing visualization of public welfare activities includes: displaying to a target user a map of a geographic region for carrying out a public welfare activity in response to the target user's selection, wherein the map comprises a first geographic location associated with a first icon indicating that the public welfare activity has been carried out at the first geographic location and a second geographic location associated with a second icon indicating that the public welfare activity is able to be carried out at the second geographic location; when a relationship exists between the target user and a public welfare activity participant user that has carried out the public welfare activity on the map, displaying on the map user information of the public welfare activity participant user; updating the second icon to be a first icon in response to the target user's selection on the second icon. 1. A method for implementing visualization of public welfare activities , implementable by a computer , comprising:displaying to a target user multiple geographic regions where a public welfare activity is able to be carried out;in response to a selection operation of the target user on one of the multiple geographic regions, determining the selected geographic region as a target geographic region for carrying out the public welfare activity;displaying to the target user a map of the target geographic region, wherein the map comprises a first geographic location associated with a first icon indicating that the public welfare activity has been carried out at the first geographic location and a second geographic location associated with a second icon indicating that the public welfare activity is able to be carried out at the second geographic location;determining user information of a public welfare activity participant user that has carried out the public welfare activity on the map;determining, based on the user information, whether a relationship exists ...

Methods, Compounds, and Compositions For Treatment and Prophylaxis in the Respiratory Tract

The present invention provides a method of reducing the quantity of mucus in the respiratory tract of a subject with elevated levels of mucus in said respiratory tract. The method includes administering to the subject a compound or composition containing a therapeutically effective amount of a fusion protein comprising a sialidase or an active portion thereof and an anchoring domain. The therapeutically effective amount comprises an amount of the fusion protein that results in a reduction of the quantity of mucus in the respiratory tract after administration of the compound or composition when compared to the quantity of mucus present prior to administration of the compound or composition. 1administering to the subject a compound or composition comprising a therapeutically effective amount of a fusion protein, whereinthe fusion protein comprises at least one catalytic domain of a sialidase, wherein the catalytic domain of the sialidase comprises the sequence of amino acids extending from amino acid 274 to amino acid 666 of SEQ ID NO:12, inclusive, and at least one anchoring domain, wherein the anchoring domain is a glycosaminoglycan (GAG) binding domain of human amphiregulin comprising the amino acid sequence of SEQ ID NO:7; andthe therapeutically effective amount comprises an amount of the fusion protein that results in a reduction of the quantity of mucus in the respiratory tract after administration of the compound or composition when compared to the quantity of mucus present prior to administration of the compound or composition.. A method of reducing the quantity or level of mucus or preventing an increase in the quantity or level of mucus in a respiratory tract of a subject, the method comprising: This application claims the benefit of U.S. patent application Ser. No. 15/865,217, filed on Jan. 8, 2018, which claims the benefit of U.S. patent application Ser. No. 15/136,751, filed on Apr. 22, 2016, which claims the benefit of U.S. patent application Ser. No. 14 ...

Method And Server For Updating Service Information

A method and server updates service information. A service information update request may be received from a mobile terminal device. The service information update request may include a user Identity (ID) of a user. Characteristic information of the user may be determined according to the user ID. Service information may be determined according to the characteristic information of the user and information relating to an area, at which the mobile terminal device may be located. The service information may be sent to the mobile terminal device. 1. A method for updating service information , comprising:receiving a service information update request from a mobile terminal device; wherein the service information update request comprises: a user Identity (ID) of a user;determining characteristic information of the user according to the user ID;determining service information of the user according to the characteristic information of the user and information relating to an area, at which the mobile terminal device is located; andsending the service information to the mobile terminal device.2. The method according to claim 1 , wherein the service information update request comprises: a traffic information request;wherein determining the characteristic information of the user according to the user ID comprises:searching for a user characteristic table recording a corresponding relationship between the user ID and a traffic characteristic according to the user ID; anddetermining the traffic characteristic of the user corresponding to the user ID.3. The method according to claim 2 , wherein determining the service information of the user according to the characteristic information of the user and the information relating to the area claim 2 , at which the mobile terminal device is located comprises:determining traffic plans between the mobile terminal device and a destination according to the traffic characteristic of the user and a traffic database of the area, at which the ...

METHOD FOR EXTRACTING STILBENE COMPOUNDS

A method for extracting stilbene compounds comprises the following steps: grinding a medicinal material rich in stilbene compounds such as ; extracting the medicinal material with a herbal flash extractor for one to four times, 5-20 minutes each time; filtering and combining filtrate and concentrating the filtrate to dryness; the proportion of the medicinal material to a solvent being 1 g: 10 ml-1 g:15 ml. 1. A method for extracting stilbenoid compounds , comprising: using a medicinal material rich in stilbenoid compounds as a raw material , extracting with a flash extractor , filtering , combining the filtrate and concentrating to dryness.2. The method according to claim 1 , comprising: using a medicinal material rich in stilbenoid compounds as a raw material claim 1 , adding a solvent after pulverizing the medicinal material claim 1 , extracting one to four times with a flash extractor for 5-20 minutes each time claim 1 , filtering claim 1 , combining the filtrate and concentrating to dryness.3Rheum lhasaenseRheum hotaoenseRheum australeRheum likiangense. The method according to claim 1 , wherein the medicinal material rich in stilbenoid compounds is one of A. J. Li et P. K. Hsiao claim 1 , C. Y Cheng et Kao claim 1 , D. Don and Sam. claim 1 , or a mixture thereof.4. The method according to claim 2 , wherein the solvent is water claim 2 , methanol claim 2 , ethanol claim 2 , acetone or a mixed solvent thereof in any ratio.5. The method according to claim 2 , wherein the solvent is methanol claim 2 , ethanol or acetone.6. The method according to claim 2 , wherein the temperature of the solvent is 20° C. to 40° C.7. The method according to claim 1 , wherein the extracting is performed one to three times.8. The method according to claim 1 , wherein the extracting is performed for 5-10 minutes each time.9. The method according to claim 2 , wherein the weight-to-volume ratio of the medicinal material to the solvent is 1:10 to 1:15.10. An extract rich in stilbenoid ...

TOUCH PANEL AND MANUFACTURING METHOD THEREFOR

A manufacturing method for a touch panel includes defining a removing area of a photo-sensitive conductive layer and a photo-sensitive layer by an exposure process. On a display area, the photo-sensitive layer and a metal nanowire layer in the removing area are removed by a developer solution so as to form a touch sensing electrode on the display area. On a peripheral area, the photo-sensitive conductive layer, the photo-sensitive layer, and the metal nanowire layer in the removing area are removed by the developer solution so as to form a peripheral trace on the peripheral area. The touch sensing electrode and the peripheral trace are electrically connected with each other. 1. A manufacturing method for a touch panel , comprising:providing a substrate, wherein the substrate comprises a display area and a peripheral area;forming a photo-sensitive conductive layer on the peripheral area;forming a metal nanowire layer on the display area and the peripheral area, wherein the metal nanowire layer comprises metal nanowires, and a part of the metal nanowire layer covers the photo-sensitive conductive layer;forming a photo-sensitive layer on the metal nanowire layer; and exposing the photo-sensitive layer and the photo-sensitive conductive layer to define a first removing area and a second removing area; and', 'removing the photo-sensitive layer and the metal nanowire layer in the first removing area by a developer solution so as to form a touch sensing electrode on the display area and simultaneously removing the photo-sensitive conductive layer, the photo-sensitive layer, and the metal nanowire layer in the second removing area by the developer solution so as to form a peripheral conductive trace on the peripheral area, wherein the touch sensing electrode is electrically connected with the peripheral conductive trace, and the touch sensing electrode at least comprises the metal nanowires., 'performing a patterning process comprising2. The manufacturing method of claim 1 ...

Traveling Assistance Method and Traveling Assistance Device

A traveling assistance method detects another vehicle and objects around a host vehicle, sets a blind spot area from the other vehicle, specifies an object present in the blind spot area among the detected objects, and predicts an action that the other vehicle takes in accordance with the specified object. 1. A traveling assistance method for predicting an action of another vehicle around a host vehicle to assist the host vehicle in traveling according to a predicted result , the method comprising:detecting the other vehicle and objects around the host vehicle;setting a blind spot area which is a blind spot from the other vehicle;specifying an object present in the blind spot area among the detected objects; andpredicting an action that the other vehicle takes in accordance with the specified object.2. The traveling assistance method according to claim 1 , further comprising predicting the action of the other vehicle in accordance with a behavior of the object present in the blind spot area.3. The traveling assistance method according to claim 1 , further comprising setting the blind spot area only in a region with a probability that the other vehicle is to travel to claim 1 , in accordance with a position of the other vehicle claim 1 , a traveling direction of the other vehicle claim 1 , and a road structure around the other vehicle.4. The traveling assistance method according to claim 1 , further comprising predicting the action that the other vehicle takes when there is an object present in the blind spot area that the other vehicle fails to recognize.5. The traveling assistance method according to claim 4 , further comprising:predicting a probability of action that the other vehicle takes when the other vehicle fails to recognize the object present in the blind spot area, in accordance with a road structure around the host vehicle; andcomparing a behavior of the other vehicle with the probability of action so as to predict the action of the other vehicle.6. The ...

Technology for the Preparation of Microparticles

Microspheres are produced by contacting a solution of a macromolecule or small molecule in a solvent with an antisolvent and a counterion, and chilling the solution. The microspheres are useful for preparing pharmaceuticals, nutraceuticals, cosmetic products and the like of defined dimensions.

Vehicle Behavior Prediction Method and Vehicle Behavior Prediction Apparatus

A vehicle behavior prediction apparatus includes: an object detection unit that detects the position of a target vehicle around a host vehicle; and a controller that acquires road structure around the position of the target vehicle including at least a traffic lane. The controller acquires a traffic rule for the road structure and predicts a route on which the target vehicle will travel, based on the acquired traffic rule.

Novel Class of Therapeutic Protein Based Molecules

The present invention provides new compositions and methods for preventing and treating pathogen infection. In particular, the present invention provides compounds having an anchoring domain that anchors the compound to the surface of a target cell, and a therapeutic domain that can act extracellularly to prevent infection of a target cell by a pathogen, such as a virus. The present invention also comprises therapeutic compositions having sialidase activity, including protein-based compounds having sialidase catalytic domains. Compounds of the invention can be used for treating or preventing pathogen infection, and for treating and reducing allergic and inflammatory responses. The invention also provides compositions and methods for enhancing transduction of target cells by recombinant viruses. Such compositions and methods can be used in gene therapy.

Object Detecting Method and Object Detecting Device

Multiple objects detected by multiple sensors are subjected to a determination as to whether or not the objects are identical to each other. If there is an object in the multiple objects, of which object position becomes undetectable after the point when the multiple objects detected by the multiple sensors are determined to be the identical object, a determination is made as to whether or not the continuously detected object is an object identical to the object in a previous processing based on a predicted range calculated from a previously detected object position of the object becoming undetectable, and on a range of presence estimated from an object position of the continuously detected object. 1. An object detecting method using an object detecting device provided with a plurality of sensors mounted on a moving body and configured to detect a position of an object around the moving body , and an object detecting circuit configured to detect an object by determining whether or not a plurality of objects detected by the plurality of sensors respectively are identical to each other , the method comprising:when ranges of presence estimated from object positions of the plurality of objects overlap each other, thereby the plurality of objects detected by the plurality of sensors respectively are determined to be the identical object, then an object position detected by a second sensor of the plurality of sensors is determined as an object position in a previous processing, the object position detected by the second sensor becomes undetectable and a first sensor of the plurality of sensors detects an object continuously later, causing the object detecting circuit to determine that the continuously detected object by the first sensor is an object identical to the object detected in a previous processing when a predicted range in a current processing calculated from the previously detected object position by the second sensor overlaps a range of presence estimated from ...

Multicopper Oxidase Mutant with Improved Salt Tolerance

The present disclosure provides a multicopper oxidase mutant with improved salt tolerance. Threonine at site 317 of wild-type multicopper oxidase WT was mutated to asparagine, leucine at site 386 was mutated to tyrosine, and serine at site 427 was mutated to glutamic acid by site-directed mutagenesis to obtain a mutant T317N-L386Y-S427E. Compared with WT, the tolerance of T317N-L386Y-S427E to 6%, 9%, 12%, 15% and 18% NaCl (W/V) is improved. 1Bacillus amyloliquefaciens. A multicopper oxidase mutant , wherein threonine at site 317 of a multicopper oxidase of is mutated to asparagine , leucine at site 386 is mutated to tyrosine , and serine at site 427 is mutated to glutamic acid.2. The multicopper oxidase mutant according to claim 1 , wherein an amino acid sequence of the multicopper oxidase mutant is set forth in SEQ ID NO: 1.3. A gene encoding the multicopper oxidase mutant according to claim 2 , wherein a nucleotide sequence is set forth in SEQ ID NO: 2.4. A cell or vector carrying the gene according to .5Escherichia coliSaccharomycesBacillus subtilisEscherichia coliSaccharomycesBacillus subtilis. A genetically engineered bacterium expressing the gene according to claim 3 , wherein or or or an eukaryotic cell other than the claim 3 , the and the is used as a host claim 3 , and the gene is expressed by a vector or the gene is integrated into a genome of the host to be expressed.6Escherichia coliEscherichia coli. A recombinant recombinantly expressing the multicopper oxidase mutant according to claim 1 , wherein BL21 is used as a host and a pET series plasmid is used as an expression vector.7Escherichia coliEscherichia coli. A method for producing a multicopper oxidase by applying the recombinant according to claim 6 , comprising: inoculating the recombinant into a medium to be cultured and inducing cells to produce the multicopper oxidase; collecting thallus cells; disrupting the cells; and obtaining the multicopper oxidase from a cell disrupting solution.8. A ...

Driving Assistance Method and Driving Assistance Device

A driving assistance method detects a behavior of a moving object causing a blind spot area around a host vehicle, predicts a probability of action that the moving object takes when an obstacle is present in the blind spot area, according to a road structure around the host vehicle, and compares the behavior of the moving object with the probability of action that the moving object takes, so as to predict an action of the moving object. 1. A driving assistance method for predicting an action of a moving object around a host vehicle to control the host vehicle according to the predicted action of the moving object , the method comprising:detecting a behavior of the moving object causing a blind spot area around the host vehicle;predicting a probability of action that the moving object takes when an obstacle which cannot be detected by the host vehicle is present in the blind spot area, according to a road structure around the host vehicle; andcomparing the behavior with the probability of action so as to predict the action of the moving object.2. The driving assistance method according to claim 1 , further comprising:generating a route of the host vehicle based on the predicted action of the moving object; andcontrolling the host vehicle in accordance with the route of the host vehicle.3. The driving assistance method according to claim 1 , further comprising:comparing the behavior with the probability of action so as to predict a course of the moving object.4. The driving assistance method according to claim 2 , further comprising:detecting a change in relative distance of the moving object to the host vehicle; andgenerating the route of the host vehicle based on the change in the relative distance.5. The driving assistance method according to claim 4 , further comprising:detecting acceleration or deceleration of the moving object as the change in the relative distance; andgenerating the route of the host vehicle based on the acceleration or the deceleration.6. The ...

Vehicle Travel Assist Method and Vehicle Travel Assist Device

A vehicle travel assist method includes detecting a surrounding object different from another vehicle A and traveling on a road toward a target intersection. The method also includes assisting the travel of the host vehicle S based on the predicted course of the surrounding object instead of the predicted course of the other vehicle A in a case where the other vehicle A is following the surrounding object. 1. A vehicle travel assist method performed by a vehicle travel assist device that assists travel of a host vehicle based on predicted courses of another vehicle traveling on a road toward an intersection and a surrounding object different from the other vehicle , comprising:detecting the surrounding object traveling on the road toward the intersection;predicting a predicted course of the other vehicle that is a direction in which the other vehicle is going to travel at the intersection based on whether the other vehicle is following the surrounding object; andassisting the travel of the host vehicle based on the predicted course of the other vehicle and the predicted course of the surrounding object.2. The vehicle travel assist method according to claim 1 , whereinin a case where the other vehicle is not following the surrounding object, the vehicle travel assist device predicts that the other vehicle will not turn, at the intersection, to a direction toward the surrounding object side from the center of the road in the width direction.3. The vehicle travel assist method according to claim 1 , whereinin a case where the other vehicle overtook the surrounding object at a constant speed in a section having a length to the intersection that is larger than a specified threshold, the vehicle travel assist device predicts that the other vehicle will not turn, at the intersection, to a direction toward the surrounding object side from the center of the road in the width direction.4. The vehicle travel assist method according to claim 1 , whereinin a case where the other ...

Vehicle-Behavior Prediction Method and Vehicle-Behavior Prediction Device

A vehicle-behavior prediction device includes: a priority determination section that determines the priority of a host vehicle and a vehicle concerned when the host vehicle and the vehicle concerned pass through a road section; and a vehicle control section that sets the time from when the vehicle concerned stops to when the host vehicle starts action to avoid the vehicle concerned to be shorter in a case where the priority of the host vehicle is low than in a case where the priority of the host vehicle is high. 1. A vehicle-behavior prediction method comprising:for a road section in which it is difficult for a host vehicle and a vehicle concerned to pass by each other,determining the priority of the host vehicle and the vehicle concerned when the host vehicle and the vehicle concerned pass through the road section; andsetting the time from when the vehicle concerned stops to when the host vehicle starts action to avoid the vehicle concerned to be shorter in a case where the priority of the host vehicle is low than in a case where the priority of the host vehicle is high.2. The vehicle-behavior prediction method according to claim 1 , whereinthe priority is determined based on an attribute of the vehicle concerned.3. The vehicle-behavior prediction method according to claim 1 , whereinthe priority is determined based on information on the surroundings of the vehicle concerned or the host vehicle.4. The vehicle-behavior prediction method according to claim 3 , whereinthe priority is determined by weighing an attribute of the vehicle concerned and the information on the surroundings of the vehicle concerned or the host vehicle.5. The vehicle-behavior prediction method according to claim 3 , whereinthe information on the surroundings of the vehicle concerned is a road structure around the vehicle concerned.6. The vehicle-behavior prediction method according to claim 5 , whereinin a case where the road structure behind the vehicle concerned is a gradient road, it is ...

TOUCH PANEL

A touch panel includes a substrate having a display area and a peripheral area. A peripheral circuit is disposed in the peripheral area. The peripheral circuit comprises at least one bonding pad made of a metal layer. A plurality of touch sensing electrodes is disposed in the display area. The plurality of touch sensing electrodes is made of a metal nanowire layer, a film layer disposed on the metal nanowire layer, and a negative-type photosensitive layer disposed on the film layer. The plurality of touch sensing electrodes is electrically connected to the peripheral circuit. 1. A touch panel , comprising:a substrate having a display area and a peripheral area;a peripheral circuit disposed in the peripheral area, wherein the peripheral circuit comprises at least one bonding pad made of a metal layer; anda plurality of touch sensing electrodes in the display area, wherein the plurality of touch sensing electrodes is made of a metal nanowire layer, a film layer disposed on the metal nanowire layer, and a negative-type photosensitive layer disposed on the film layer, wherein the plurality of touch sensing electrodes is electrically connected to the peripheral circuit.2. The touch panel of claim 1 , wherein the metal nanowire layer comprises a plurality of metal nanowires embedded in the film layer.3. The touch panel of claim 1 , wherein a photosensitivity of the negative-type photosensitive layer is greater than a photosensitivity of the film layer.4. The touch panel of claim 1 , wherein a thickness of the film layer ranges from about 200 nm to 400 nm.5. The touch panel of claim 1 , wherein the metal nanowire layer and the peripheral circuit form a connection structure at an interface of the display area and the peripheral area.6. The touch panel of claim 1 , wherein-the metal nanowire layer protrudes from the display area to the peripheral area claim 1 , such that one end of the metal nanowire layer climbs on and contacts the peripheral circuit.7. The touch panel of ...

OPTICAL ASSEMBLY AND VEHICLE LAMP

An optical assembly and a vehicle lamp are described. The optical assembly has a main exit direction, and includes a light source, a first light guide element and a second light guide element which are arranged in a superposed fashion in the main exit direction. The light source is allocated to the first light guide element, and the first light guide element has a first light in-coupling region and a first light out-coupling surface, the second light guide element has a second light in-coupling surface and a second light out-coupling surface, with the first light out-coupling surface facing the second light in-coupling surface. A light distribution structure is provided on at least a partial segment of at least one of the first light out-coupling surface and the second light in-coupling surface. The vehicle lamp includes the optical assembly described above. 1. An optical assembly , including a main exit direction , the optical assembly comprising:a light source;a first light guide element;a second light guide element, with the first light guide element and the second light guide element arranged in a superposed fashion in the main exit direction, with the light source allocated to the first light guide element, with the first light guide element including a first light in-coupling region and a first light out-coupling surface, the second light guide element including a second light in-coupling surface and a second light out-coupling surface, the first light out-coupling surface facing the second light in-coupling surface; andwherein a light distribution structure is provided on at least a partial segment of at least one of the first light out-coupling surface and the second light in-coupling surface.2. The optical assembly according to claim 1 , wherein the first light guide element is a light guide rod claim 1 , the second light guide element is a light guide block claim 1 , and a length running direction of the first light guide element corresponds to a length ...

Humanized antibodies

Humanized antibodies that bind ICAM-1 are provided. Antibodies include those selected from: SEQ ID NO:1 and 3 (HumA); SEQ ID NO:5 and 7 (HumB); SEQ ID NO:9 and 11 (HumC); SEQ ID NO:13 and 15 (HumD); SEQ ID NO:17 and 19 (HumE); SEQ ID NO:21 and 23 (HumF); SEQ ID NO:25 and 27 (HumG); SEQ ID NO:29 and 31 (HumH); and SEQ ID NO:33 and 35 (HumI). Subsequences of the humanized antibodies capable of binding an ICAM-1 epitope are also provided. Methods of inhibiting pathogen infection (e.g., HRV) of a cell employing humanized antibodies capable of binding an ICAM-1 epitope are further provided.

Multimeric proteins and methods of making and using same

Method for extracting alpha-ketoglutarate and pyruvate simultaneously from microbial fermentation broth or enzymatic conversion solution

The present disclosure provides a method for extracting alpha-ketoglutarate and pyruvate simultaneously from microbial fermentation broth or enzyme transformation solution, which is related to the technical field of biological separation and extraction. The method comprises the following steps: centrifuging the microbial fermentation broth or enzymatic conversion solution containing α-KG and PA to remove the cells and other visible solids; removing the macromolecular impurities by ultrafiltration; evaporating and concentrating under reduced pressure conditions; extracting with the water-insoluble extraction after acidification; separating crude crystals of α-KG and crude liquid of PA by evaporation crystallization method (if concentration of PA is great higher than that of α-KG, crystallization separation should be conducted after distilling partial pure pyruvate); washing the crude crystal of α-KG with water-insoluble organic solvent as ethyl acetate or butyl acetate, drying and crushing to obtain qualified α-KG; distilling to gain qualified PA product applying high vacuum distillation (or molecular distillation).

Electrophoretic display system

An electrophoretic display system includes an electrophoretic display panel, a timing controller, a data driver, and a gate driver. The data driver includes a first serial-to-parallel converter and a data converter. The first serial-to-parallel converter receives a plurality of first series data and converts the first series data into a plurality of second series data. The quantity of the second series data is more than the quantity of the first series data. The data converter receives the second series data and is electrically connected to the electrophoretic display panel. Besides, the data converter converts the second series data into display voltages, and the quantity of the display voltages is more than the quantity of the second series data. The gate driver is electrically connected to the electrophoretic display panel and the timing controller and controlled by the timing controller to provide gate driving voltages to the electrophoretic display panel.

Call transfer with multiple application servers in session initiation protocol-based network

Call transfer techniques between multiple application servers in a SIP-based network or other type of communication network are disclosed. In accordance with one example technique of the invention, it is assumed that a first call is established between a first user device and a second user device via a first server, and the second user device, wishing to initiate a call transfer to a third user device, establishes a second call between itself and the third user device via a second server. Thus, the technique includes the following steps. Upon the first server receiving a call transfer request from the second user device such that the first user device and the third user device can communicate, it is determined whether the first server has information that matches the second call. Upon determining that the first server does not have information matching the second call, a message is sent from the first server to the second server so as to obtain information from the third device such that the first user device and the third user device can communicate via the first server. The message sent from the first server to the second server indicates that the call transfer request was referred by the second user device.

Methods and systems for detection of prostate cancer by DNA methylation analysis

The present disclosure provides methods and systems directed to detection of prostate cancer. A method for processing or analyzing DNA molecules from a biological sample of a subject may comprise processing (a) providing a first set of DNA fragments derived from a first portion of the DNA molecules upon subjecting the first portion to CpG site fragmentation conditions; (b) providing a second set of DNA fragments derived from a second portion of the DNA molecules, the second portion not subjected to fragmentation conditions; (c) for a genomic region, processing the first and the second sets of DNA fragments or derivatives thereof to yield first and second quantitative measures of DNA methylation; and (d) processing the first quantitative measure with the second quantitative measure to yield a third quantitative measure of DNA methylation at the genomic region, thereby generating a methylation profile of the DNA molecules at the genomic region.