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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 121. Отображено 121.
31-07-2000 дата публикации

Methods of characterizing drug activities using consensus profiles

Номер: AU0002377000A
Принадлежит:

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01-08-2023 дата публикации

Operation vehicle control method and device, electronic equipment and storage medium

Номер: CN116520854A
Автор: HE YUDONG
Принадлежит:

The invention relates to an operation vehicle control method and device, electronic equipment and a storage medium. The method is applied to unmanned equipment, namely automatic driving equipment or an unmanned vehicle, and comprises the following steps: acquiring an initial operation destination of an operation vehicle, and calculating initial operation data of driving from a current position of the operation vehicle to the initial operation destination; determining a replacement work destination of the work vehicle, and calculating target operation data for driving from the current position of the work vehicle to the replacement work destination, the replacement work destination being a work destination obtained by changing the initial work destination; under the condition that it is determined that the initial operation destination is changed into the replacement operation destination based on the initial operation data and the target operation data, whether the replacement operation ...

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27-05-2015 дата публикации

Magnetic photo combination plate

Номер: CN104643751A
Автор: HE YUDONG
Принадлежит:

The invention relates to a magnetic photo combination plate which comprises at least four square metal covers. Every four adjacent metal covers are integrally connected into a whole through a connecting seat, cover faces of the metal covers can serve as hanging faces where photos can be hung, and the photos can be hung on the cover faces of the metal covers through magnetic parts. The adjacent metal covers can be in plug connection, so that a plurality of metal covers can be spliced together. Due to the fact that the metal covers can be expanded and spliced infinitely through connecting parts, combination plates of different sizes can be spliced according to requirements. For example, the magnetic photo combination plate can be used as a small photo frame where only 1 to 4 photos are hung, and a lot of photos can be hung on the magnetic photo combination plate at the same time to achieve a photo wall effect. Furthermore, the photos can be changed often and are convenient to hang and take ...

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12-05-2023 дата публикации

Preparation method of blade steel with high transverse-longitudinal impact ratio

Номер: CN116103582A
Принадлежит:

The invention discloses a preparation method of blade steel with a high transverse-longitudinal impact ratio. The preparation method comprises the steps that an electroslag ingot is heated and subjected to heat preservation; the heated steel ingot is subjected to fast forging cogging, and the fast forging cogging adopts two-time upsetting and two-time drawing; the steel ingot obtained after fast forging is subjected to precision forging forming; carrying out annealing heat treatment on the forge piece subjected to precision forging; the blade steel comprises the following components: 0.08%-0.17% of C, less than or equal to 0.3% of Si, 0.50%-0.90% of Mn, 11.0%-12.75% of Cr, 2.0%-3.0% of Ni, 1.50%-2.00% of Mo, 0.25%-0.40% of V, 0.01%-0.05% of N, less than or equal to 0.04% of Al and the balance of Fe and impurity elements. According to the method, the transverse and longitudinal impact ratio of the blade steel reaches 92% or above through control over chemical components, thermal deformation ...

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04-03-2015 дата публикации

Clock design method and clock device

Номер: CN0101621371B
Автор: HE YUDONG
Принадлежит:

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23-06-2023 дата публикации

Regulation and control method of wet desulphurization slurry anti-blinding wide-load regulation and control system

Номер: CN116272323A
Принадлежит:

The invention relates to a regulation and control method of a wet desulphurization slurry anti-blinding wide-load regulation and control system. At present, an opening degree control method of a slurry supply regulating valve of an existing slurry supply system is generally a proportional integral differential regulation method based on a pH value in an absorption tower, and the control method has a poor control effect on the concentration of sulfur dioxide in discharged flue gas. A regulation and control method of the wet desulphurization slurry anti-blinding wide-load regulation and control system comprises the following steps: calculating and establishing a slurry balance model through an absorption tower pH value change curvature and slurry supply amount recorded by the processor module, so that the replenished slurry amount is the same as the actually required slurry amount for absorbing sulfur dioxide; the method comprises the steps of slurry proportioning, real-time slurry pH value ...

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17-12-2014 дата публикации

High-efficiency desulfurized active coke analysis tower and analysis method

Номер: CN104209107A
Принадлежит:

The invention discloses a high-efficiency desulfurized active coke analysis tower and an analysis method. The analysis tower comprises a material feeding section, a preheating section, a first buffering section, an analysis section, a second buffering section, a cooling section and a material discharging section which are communicated with one another in sequence from top to bottom, wherein the preheating section, the analysis section and the cooling section are all of tube-shell type heat exchange structures; a cooling section gas inlet is formed in the lower part of the cooling section, and a cooling section gas outlet is formed in the upper part of the cooling section and is communicated with an analysis section gas inlet formed in the lower part of the analysis section; an analysis section gas outlet formed in the upper part of the analysis section is communicated with a preheating section gas inlet formed in the lower part of the preheating section; a preheating section gas outlet ...

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14-05-2008 дата публикации

Clock phase-locked method to extract synchronous clock of global positioning system and clock phase-locked loop

Номер: CN0101179371A
Автор: YUDONG HE, HE YUDONG
Принадлежит:

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05-05-2010 дата публикации

Heating process of low-temperature flue gas with wetting flue gas desulphurization

Номер: CN0101701717A
Принадлежит:

The invention relates to a heating process of low-temperature flue gas with wetting flue gas desulphurization; an adsorption tower is directly connected with a chimney by a pipeline, and a hot secondary air pipe of a boiler air preheater, which is used for heating low-temperature flue gas at the outlet of an absorption tower, is connected on the pipeline for connecting the absorption tower and the chimney. In the invention, GGH (Gas GasHeater) is removed to thoroughly solve the problems that the heating effect is poor, the desulphurization performance is unstable, availability factor is low and the operation is dis-economic owning to GGH scaling and blocking, so as to reduce the service-power consumption rate of a desulphurization system; in addition, the invention has flexible adjustability, can heat the low-temperature flue gas at the outlet of the absorption tower of the desulphurization device to the temperature needed by safe discharge by pumping secondary wind along with the change ...

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27-01-2010 дата публикации

System and method of automatic phase-locking tracking of clock synchronization

Номер: CN0100586057C
Автор: YUDONG HE, HE YUDONG
Принадлежит:

The invention relates to a system and method for locking phase and tracing the time synchronization, the said system includes: the receiver of clock source which is used to receive the second impulse signal and state data of clock source; control device for clock phase-lock which is connected with the receiver of clock source, read the state data of clock source and analyses it to choose a route to trace the second impulse signal, and the traced signal is output according to the need of user. Said method includes: a. receiving the second impulse signal from the clock source and state data; b. analyzing the state data of clock source, and according to the analyzed result choose the second impulse signal; c. tracing the second impulse signal by locking phase and output the signal according to need frequence of user. To solve the problem that caused by using the receiving unit of ''Dipper No. 1'' need to provide local parameters which is lack by hand; and at the same time, it solves the unreliable ...

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30-06-2005 дата публикации

Methods for characterizing tissue or organ condition or status

Номер: US2005143628A1
Принадлежит:

The invention provides methods for characterizing the condition or status of a tissue or organ in a multicellular organism, e.g., an animal, by combining a plurality of clinical measures are combined into a composite clinical score (CCS) and using such a CCS to represent the condition or status of the tissue or organ. The invention provides methods for predicting the condition or status of a tissue or organ in a multicellular organism, e.g., an animal, based on measurements of a set of cellular constituent markers, e.g., measured expression levels of a set of marker genes. The invention also provides methods for selecting the set of marker genes whose expression levels can be used in determining the CCS.

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27-09-2005 дата публикации

Methods for removing artifact from biological profiles

Номер: US0006950752B1

The invention provides methods for removing unwanted response components (i.e., “artifacts”) from a measured biological profile comprising measurements of a plurality of cellular constituents of a cell or organism in response to a perturbation. The methods involve subtracting from the measured biological profile one or more artifact patterns, each of which comprises measurements of changes in cellular constituents as a result of deviation of one or more experimental variables, such as cell culture density and temperature, hybridization temperature, as well as concentrations of total RNA and/or hybridization reagents, from desired values.

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17-02-2010 дата публикации

Grout mixing technology of desulphurization tower and subsidiary tower/grout tank and system

Номер: CN0101648111A
Принадлежит:

The invention relates to a grout mixing technology of a desulphurization tower and a subsidiary tower/grout tank and a system. The lower ends of a main tower and a subsidiary tower/grout tank outsidethe tower are communicated by a tilted communicating pipe, the main tower and the subsidiary tower adopt a grout circulation pump to transport spray grout alternately, or the grout tank outside the tower adopts the grout circulation pump to transport spray grout to the main tower. In the main tower and the subsidiary tower/grout tank outside the tower in the invention, the tilted communicating pipe adopted can effectively prevent grout from deposition or blockage in the communicating pipe, the alternate transportation of spray grout by a pump can effectively realize even mixing of the grout ofthe main tower and the subsidiary tower/grout tank outside the tower, and simultaneously the power consumption can be reduced by cancelling a grout exchange pump in a grout pool.

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18-07-2023 дата публикации

Construction method of reserved hole in cast-in-place floor plate

Номер: CN116446646A
Принадлежит:

The invention discloses a construction method of a reserved hole in a cast-in-place floor plate. The problems that a mold of an existing reserved hole cannot be repeatedly used, and the construction cost is high are solved. A stand column (1) is vertically arranged at the center of a reserved hole (22) in a floor plate pouring bottom formwork (23), a lower limiting pin hole (4) is formed in the lower portion of the stand column (1), the stand column above a cylindrical lower limiting step (2) is movably sleeved with a fourth lantern ring (11), the stand column above the fourth lantern ring (11) is movably sleeved with a lower compression spring (7), and the lower compression spring (7) is sleeved with a lower limiting pin hole (8). A third lantern ring (10) is movably sleeved on the upright post above the lower pressure spring; cantilever rods are radially arranged on the two lantern rings, lower arc-shaped vertical plates are hinged to the outer ends of the corresponding upper and lower ...

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10-03-2010 дата публикации

Method and device for switching clock integrated circuit boards

Номер: CN0101667905A
Автор: HE YUDONG, YUDONG HE
Принадлежит:

The invention discloses a method and a device for switching clock integrated circuit boards. The method comprises the following steps: a first clock integrated circuit board and a second clock integrated circuit board send heartbeat signals and working state information to each other through a communication interface between the integrated circuit boards; and the first clock integrated circuit board and the second clock integrated circuit board determine whether to initiate active-standby status switching according to the heartbeat signals, the active and standby statuses and the working stateinformation of the two clock integrated circuit boards, and send enabling signals to each other through a two-computer logical connection interface between the first clock integrated circuit board and the second clock integrated circuit board so that the active and standby statues of the first clock integrated circuit board and the second clock integrated circuit board are maintained to be mutually ...

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04-07-2023 дата публикации

SPMA protocol priority threshold and channel load window length design method

Номер: CN116390172A
Принадлежит:

The invention discloses an SPMA protocol priority threshold and channel load window length design method, and the method comprises the steps: independently setting a highest priority threshold, setting the rest priority thresholds to be the same, and setting the rest priority thresholds to be lower than the highest priority threshold; and respectively setting a channel load window of each priority service, the channel load windows of each priority service being different from each other, and the lower the service priority is, the longer the channel load window is. According to the method, the threshold and the window length are simple to set, only the physical layer channel load needs to be counted, backoff and overtime discarding services do not need to be counted through a network layer, channel resources can be saved, and the method is more reliable and easy to implement.

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25-01-2012 дата публикации

Magnetic clothes hanger and clothes airing tool used with same

Номер: CN0202122439U
Автор: YUDONG HE, HE YUDONG
Принадлежит: YUDONG HE, HE YUDONG

The utility model relates to a magnetic clothes hanger protected from sliding and being blown off and a clothes airing tool used with same. The magnetic clothes hanger is mainly characterized in that a magnet is mounted on a hook of the clothes hanger, and iron plates are accordingly distributed at intervals on a clothes airing rope or a clothes airing rod. Therefore, when the magnetic clothes hanger is used, the magnetic on the clothes hanger and the iron plates on the clothes airing rope or the clothes airing rod can be conveniently attracted together, and hangers are effectively prevented from getting together by sliding or being blown off.

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07-08-2008 дата публикации

Classification of Breast Cancer Patients Using a Combination of Clinical Criteria and Informative Genesets

Номер: US2008187909A1
Принадлежит:

The present invention provides prognostic methods for conditions such as cancer, for example, breast cancer, comprising classifying an individual by a plurality of phenotypic, genotypic or clinical characteristics of the condition into a plurality of patient subsets, and analyzing the pattern of expression of prognosis-informative genes identified for that subset in a sample from the individual. The present invention also provides methods for constructing such patient subsets and of identifying prognosis-informative genesets for such subsets. The invention further provides methods of assigning a therapeutic regimen to an individual, microarrays useful for performing prognosis, kits comprising these microarrays, and computer systems and programs for implementing the methods of the invention.

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11-03-2015 дата публикации

Measuring method for pseudo code delay of spread spectrum signal with high dynamic range and low signal-to-noise ratio

Номер: CN104407323A
Принадлежит:

The invention discloses a measuring method for pseudo code delay of a spread spectrum signal with high dynamic range and low signal-to-noise ratio. A spread spectrum receiver is used for performing ADC (Analog to Digital Converter) sampling on an intermediate frequency analog signal; the intermediate frequency analog signal is subjected to digital downconversion to obtain a baseband complex signal r(k)=I(k)+jQ(k); the baseband complex signal is simultaneously outputted to a pseudo code capturing unit, a carrier and pseudo code closed-loop tracking unit and a pseudo code time delay open-loop estimation unit; the carrier and pseudo code closed-loop tracking unit is used for tracking carrier frequency and pseudo code phase according to the captured doppler frequency and pseudo code phase information; a pseudo code time delay measuring pulse is used for outputting the doppler frequency and the pseudo code phase information to the pseudo code time delay open-loop estimation unit and outputting ...

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29-10-2020 дата публикации

AUTOMOBILE WHEEL HUB SHAPING DEVICE

Номер: US20200338627A1
Принадлежит:

The present disclosure discloses an automobile wheel hub shaping device. The automobile wheel hub shaping device includes a clamping part for clamping a wheel hub to be shaped, a first driving mechanism for driving the clamping part to rotate, a shaping roller for shaping the wheel hub to be shaped, and a rack; all the clamping part, the first driving mechanism and the shaping roller are mounted to the rack, the shaping roller is located above the clamping part and is capable of rotating relative to the clamping part; and the clamping part is equipped with a fixing part for fixing the wheel hub to be shaped. 1. An automobile wheel hub shaping device , comprising a clamping part for clamping a wheel hub to be shaped , a first driving mechanism for driving the clamping part to rotate , a shaping roller for shaping the wheel hub to be shaped , and a rack; all of the clamping part , the first driving mechanism and the shaping roller being mounted to the rack , the shaping roller being located above the clamping part , and the shaping roller being capable of moving relative to the clamping part; and the clamping part being equipped with a fixing part for fixing the wheel hub to be shaped.2. The automobile wheel hub shaping device of claim 1 , wherein the clamping part comprises a locating shaft matched with an axle hole of the wheel hub to be shaped and a supporting disc matched with an inner cavity of the wheel hub to be shaped claim 1 , the locating shaft and the supporting disc are fixed together claim 1 , and the axes of the locating shaft and the supporting disc are superposed; and the clamping part is capable of rotating relative to the rack by taking an axis of the supporting disc as an axis.3. The automobile wheel hub shaping device of claim 2 , wherein the clamping part further comprises a locking ring for locking the wheel hub to be shaped claim 2 , an inner wall of the locking ring is provided with internal thread claim 2 , and the locating shaft is provided ...

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07-04-2023 дата публикации

Static mixer and static mixer set

Номер: CN115920686A
Принадлежит:

The invention discloses a static mixer and a static mixer group, the static mixer comprises a frame, an anti-drag plate and blades, the cross section of the frame is rectangular, and the frame is provided with an air inlet and an air outlet; the resistance reduction plates are connected into the frame, the plate surfaces of the resistance reduction plates are parallel to the axis direction of the frame, the multiple resistance reduction plates are connected into the frame, and a plurality of channels are defined by the multiple resistance reduction plates and the frame; the multiple blades correspond to the multiple channels in a one-to-one mode, the blades are located in the corresponding channels, the included angle between the windward side of each blade and the plate face of the corresponding anti-drag plate is an obtuse angle, the blades are connected with the anti-drag plates and the frame, and the multiple blades are distributed in the circumferential direction of the central axis ...

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06-03-2018 дата публикации

Diagnosis and prognosis of breast cancer patients

Номер: US0009909185B2

The present invention relates to genetic markers whose expression is correlated with breast cancer. Specifically, the invention provides sets of markers whose expression patterns can be used to differentiate clinical conditions associated with breast cancer, such as the presence or absence of the estrogen receptor ESR1, and BRCA1 and sporadic tumors, and to provide information on the likelihood of tumor distant metastases within five years of initial diagnosis. The invention relates to methods of using these markers to distinguish these conditions. The invention also relates to kits containing ready-to-use microarrays and computer software for data analysis using the statistical methods disclosed herein.

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05-10-2004 дата публикации

Methods of characterizing drug activities using consensus profiles

Номер: US0006801859B1

The present invention provides methods for enhanced detection of biological response profiles. In particular, the methods of this invention allow for the detection of biological response patterns, such as gene expression patterns, in response to different drug treatments. The methods of the invention also allow the determination of a “consensus profile” which describes a particular class or type of biological response. In certain embodiments the consensus profile may describe the biological response of a particular group or class of drugs. In other embodiments, the consensus profile may describe an “ideal” biological response such as one associated with a desired therapeutic effect. The methods of the present invention also allow for the comparison of different biological responses. Thus, the methods of the invention may be used, e.g., to identify and/or study new drugs.

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27-08-2001 дата публикации

METHODS FOR USING CO-REGULATED GENESETS TO ENHANCE DETECTION AND CLASSIFICATION OF GENE EXPRESSION PATTERNS

Номер: KR20010081098A
Принадлежит:

The present invention provides methods for enhanced detection of biological response patterns. In one embodiment of the invention, genes are grouped into basis genesets according to the co-regulation of their expression. Expression of individual genes within a geneset is indicated with a single gene expression value for the geneset by a projection process. The expression values of genesets, rather than the expression of individual genes, are then used as the basis for comparison and detection of biological response with greatly enhanced sensitivity. In another embodiment of the invention, biological responses are grouped according to the similarity of their biological profile. The methods of the invention have many useful applications, particularly in the fields of drug development and discovery. For example, the methods of the invention may be used to compare biological responses with greatly enhanced sensitivity. The biological responses that may be compared according to these methods ...

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30-01-2007 дата публикации

Methods of assigning treatment to breast cancer patients

Номер: US0007171311B2

The present invention relates to genetic markers whose expression is correlated with breast cancer. Specifically, the invention provides sets of markers whose expression patterns can be used to differentiate clinical conditions associated with breast cancer, such as the presence or absence of the estrogen receptor ESR1, and BRCA1 and sporadic tumors, and to provide information on the likelihood of tumor distant metastases within five years of initial diagnosis. The invention relates to methods of using these markers to distinguish these conditions. The invention also provides methods of classifying and treating patients based on prognosis. The invention also relates to kits containing ready-to-use microarrays and computer software for data analysis using the diagnostic, prognostic and statistical methods disclosed herein.

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02-01-2013 дата публикации

Method and circuit for eliminating two-shipper control circuit dithering

Номер: CN0101465670B
Принадлежит:

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08-03-2017 дата публикации

Large -scale automatic feeding equipment that mixes machine

Номер: CN0205995394U

The utility model provides a large -scale automatic feeding equipment that mixes machine belongs to the machining field, and it includes base, elevating platform and mount table, installs elevating system between base and the elevating platform, and the mount table sets up the one side of keeping away from the base in the elevating platform, and rotates with the elevating platform and be connected, and the spacing groove that is used for placing the feed bin is offered in the one side of keeping away from the base to the mount table, and the lateral wall of mount table is provided with two at least transfer arms, and the transfer arm is articulated mutually with the lateral wall of mount table. This kind of large -scale automatic feeding equipment that mixes machine, the manual work cost has been saved to the convenient quick -witted material loading of large -scale mixture of giving, improves material loading efficiency, reduction in production cost, and the simple structure of this kind ...

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26-09-2007 дата публикации

Body nursing health care nutritious yellow rice wine

Номер: CN0101041801A
Автор: HE YUDONG, YUDONG HE
Принадлежит:

The invention discloses a hygienic and nutritious yellow rice wine, which is characterized by the following: allocating with mass percent at 99.49-72% based wine of yellow rice wine, 0.01-18% low polyxylose and 0.5 -10% bee honey; producing the yellow rice wine. This invention organic merges super strong isomaltose hypgather of low polyxylose and bee honey and nutrition of yellow rice wine, which is fit for consumer conception of modern people.

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18-06-2009 дата публикации

Diagnosis and prognosis of breast cancer patients

Номер: US2009157326A1
Принадлежит:

The present invention relates to genetic markers whose expression is correlated with breast cancer. Specifically, the invention provides sets of markers whose expression patterns can be used to differentiate clinical conditions associated with breast cancer, such as the presence or absence of the estrogen receptor ESR1, and BRCA1 and sporadic tumors, and to provide information on the likelihood of tumor distant metastases within five years of initial diagnosis. The invention relates to methods of using these markers to distinguish these conditions. The invention also relates to kits containing ready-to-use microarrays and computer software for data analysis using the statistical methods disclosed herein.

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13-08-2009 дата публикации

METHODS FOR USING CO-REGULATED GENESETS TO ENHANCE DETECTION AND CLASSIFICATION OF GENE EXPRESSION PATTERNS

Номер: US2009204333A1
Принадлежит:

The present invention provides methods for enhanced detection of biological response patterns. In one embodiment of the invention, genes are grouped into basis genesets according to the co-regulation of their expression. Expression of individual genes within a geneset is indicated with a single gene expression value for the geneset by a projection process. The expression values of genesets, rather than the expression of individual genes, are then used as the basis for comparison and detection of biological response with greatly enhanced sensitivity. In another embodiment of the invention, biological responses are grouped according to the similarity of their biological profile. The methods of the invention have many useful applications, particularly in the fields of drug development and discovery. For example, the methods of the invention may be used to compare biological responses with greatly enhanced sensitivity. The biological responses that may be compared according to these methods ...

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05-11-2008 дата публикации

Phase discriminator, phase demodulation method and phase-locked loop

Номер: CN0101299609A
Автор: HE YUDONG, YUDONG HE
Принадлежит:

The invention discloses a phase discriminator for receiving the reference clock signal and the local pulse clock signal, including a frequency division module for performing the two divided-frequency to the received reference clock signal and outputting the two divided-frequency signal; a time delay module, for delaying the two divided-frequency signal and outputting the time delay signal, wherein the delay time is a local pulse clock period; a phase discrimination module for receiving the two divided-frequency signal and the time delay signal using the local pulse clock signal as the count clock, counting the local pulse clock signal in the time slot of the high level pulse width or the low level pulse width and starting counting again. The invention also discloses a phase discrimination method and a locking ring. The phase discriminator and the phase discrimination method have no specific requirement on the input signal frequency, directly judge the correctness of the phase discrimination ...

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29-04-2009 дата публикации

Time clock phase locking loop controlling method and apparatus

Номер: CN0101420294A
Автор: HE YUDONG, YUDONG HE
Принадлежит:

The present invention provides a clock phase-locked loop control method and a device thereof. The device comprises a phase reference clock source for outputting phase reference clock signals with a predetermined phase; a phase discriminator for discriminating phases of the clock signals output by the clock driver and the phase reference clock signals; a processor for outputting control parameters according to a frequency phase discrimination value output by the frequency phase discriminator and a phase discrimination value output by the phase discriminator; a local clock control source for outputting clock signals having the same frequency with clock signals output by the frequency reference clock source and having the same phase with the phase reference clock signals according to control parameters, thus, the phase of output clock signals can be controlled under the condition that the frequency of clock signals output by the local clock control source is the same as that of the clock signals ...

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18-06-2009 дата публикации

DIAGNOSIS AND PROGNOSIS OF BREAST CANCER PATIENTS

Номер: JP2009131262A
Принадлежит:

PROBLEM TO BE SOLVED: To provide genetic markers whose expression is correlated with breast cancer, specifically, sets of markers whose expression patterns can be used to differentiate clinical conditions associated with breast cancer, such as the presence or absence of the estrogen receptor ESR1, and BRCA1 and sporadic tumors, and to provide information on the likelihood of tumor distant metastases within five years of initial diagnosis. SOLUTION: The invention relates to methods of using these markers to distinguish these conditions. The invention also relates to kits containing ready-to-use microarrays and computer software for data analysis using the statistical methods disclosed herein. COPYRIGHT: (C)2009,JPO&INPIT ...

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25-03-2015 дата публикации

Mist eliminator plate form combination with variable gas flow rates

Номер: CN104436875A
Принадлежит:

The invention discloses a mist eliminator plate form combination with variable gas flow rates. The mist eliminator plate form combination comprises a plurality of mist eliminator plates which are parallelly distributed at equal intervals, wherein each mist eliminator plate comprises an accelerating section, a decelerating section, a turning section and an outlet section sequentially; accelerating sections of two adjacent mist eliminator plates form an accelerating channel, decelerating sections of two adjacent mist eliminator plates form a decelerating channel, turning sections of two adjacent mist eliminator plates form a turning channel, and outlet sections of two adjacent mist eliminator plates form an outlet channel; and the accelerating channel, the decelerating channel, the turning channel and the outlet channel of the two adjacent mist eliminator plates are communicated sequentially, the area of the cross section of the accelerating channel is reduced gradually in the air flow flowing ...

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10-06-2015 дата публикации

Elastic mobile phone rack

Номер: CN104702745A
Автор: HE YUDONG
Принадлежит:

The invention discloses an elastic mobile phone rack. The elastic mobile phone rack comprises a rack body for erecting a mobile phone, a coiling spring, and a first connecting seat for connecting the rack body to the coiling spring; the outer end of the coiling spring is the free end which can be freely coiled under the force of the spring; the coiling spring can be elastically clamped to an article to be fixed by the mobile phone rack through the free end; the first connecting seat is movably connected with the coiling spring by an adjusting manner, thus the first connecting seat can be fixed to a proper part of the coiling spring as the free end of the coiling spring coils. According to the elastic mobile phone rack, the coiling spring can be directly clamped to the article (such as back of a chair, a table top, various wall surfaces, and all places suitable for clamping) to be fixed by the mobile phone rack under the elasticity effect, thus a mobile phone can be used for reading, watching ...

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04-06-2014 дата публикации

Novel downstream tower-countercurrent tower series-connected flue gas desulphurization apparatus

Номер: CN103831006A
Принадлежит:

A novel downstream tower-countercurrent tower series-connected flue gas desulphurization apparatus comprises a first-grade downstream absorbing tower and a second-grade countercurrent absorbing tower, and a connecting flue communicating the first-grade downstream absorbing tower with the second-grade countercurrent absorbing tower; the first-grade downstream absorbing tower comprises a first-grade downstream absorbing tower inlet disposed at the upper part; a first-grade absorbing tower slurry pool disposed at the lower part of the first-grade downstream absorbing tower; a first-grade absorbing tower slurry supplying pump and a first-stage absorbing tower circulating pump which are connected with the first-grade absorbing tower slurry pool; a first-grade absorbing tower spraying layer which is disposed at the upper part of the first-grade downstream absorbing tower and is connected with the first-stage absorbing tower circulating pump through a first-stage absorbing tower circulating pump ...

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01-06-2011 дата публикации

Medicine for treating chronic gastritis

Номер: CN0101190245B
Автор: HE YUDONG, YUDONG HE
Принадлежит:

The invention relates to the field of Chinese traditional medicine technology, in particular to a medicine used for treating chronic gastritis. The invention aims at overcoming the problems of poor treatment effect and easy recurrence existing in the prior art by providing the medicine used for treating chronic gastritis. The technical proposal of the invention for overcoming the problems existing in the prior art is that: the medicine used for treating chronic gastritis is characterized in that the active ingredient thereof consists of brucea javanica oil and seabuckthorn oil and the proportion by weight is that: the brucea javanica oil : the seabuckthorn oil equals to 1: 1 to 8. The medicine includes various preparation forms such as soft capsules, oral emulsion, capsules, granules, tablets, injection, etc.

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27-04-2021 дата публикации

Wheel hub molding and casting die and preparation process thereof

Номер: US0010987726B2

A wheel hub molding and casting die includes: a casting die shell, a supporting bottom plate, a limiting bottom plate, a lifting module, a module supporting plate, a lower die, an upper die and removable plates. The supporting bottom plate is mounted on the lower surface of the casting die shell. The limiting bottom plate is arranged below the supporting bottom plate. The module supporting plate is movably arranged in a molding cavity. The lifting module is connected between the bottom of the molding cavity and the module supporting plate. The lower die and the upper die are closed to form a pouring cavity. Annular slots are formed in the outer side wall of the upper die. Removable plate slots are formed in the upper surface of the casting die shell.

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06-01-2010 дата публикации

Clock design method and clock device

Номер: CN0101621371A
Автор: HE YUDONG, YUDONG HE
Принадлежит:

The invention discloses a clock design method, which comprises the following steps that: one path or a plurality of paths of clock source signals are input to two clock phase locking plate cards; each of the clock phase locking plate cards outputs a path of active/backup signals which are connected to a clock driving plate card, each clock phase locking plate card provides a path of clock signals for each clock driving plate card, the two clock phase locking plate cards provide the clock signals to each other, and the two clock phase locking plate cards are connected through a double-computer mutual control wire; and each clock driving plate card distributes the clock signals to the equipment which needs clocks. The invention also discloses a clock device and a method for controlling a clock system. The technical scheme provided by the invention can provide reliable clock signals for the communication equipment. The clock design method provided by the invention has a clear structure and ...

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07-10-2015 дата публикации

Arc double hook way defroster

Номер: CN0204684797U
Принадлежит:

The utility model discloses an arc double hook way defroster, by a plurality of even spacing distribution's defroster blades, the defroster blade is by the entrance, defogging section and export section are constituteed, the both ends of defogging section are connected with entrance and export section respectively, the both sides face of defogging section is equipped with main hook board and auxiliary hook board respectively, an access road has been constituteed to the entrance of two adjacent defroster blades, a defogging passageway has been constituteed to the defogging section of two adjacent defroster blades, an exit channel has been constituteed to the export section of two adjacent defroster blades, and access road, the consecutive expert of defogging passageway and exit channel, the defogging in -process, the air current passes through earlier the auxiliary hook board again behind the main hook board. The utility model has the characteristics of comprehensive desorption to liquid ...

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31-03-2010 дата публикации

Device and method for realizing clock synchronization

Номер: CN0101686120A
Автор: HE YUDONG, YUDONG HE
Принадлежит:

The invention relates to a device and a method for realizing clock synchronization. The device comprises an Ethernet interface, a phase-locked loop unit and a clock generation unit, wherein the phase-locked loop unit comprises a logic control circuit, a microprocessor, a digital-to-analogue converter and a voltage controlled oscillator or a direct digital frequency synthesizer. The method comprises the following steps: extracting clock signals; performing phase-locked loop processing on the clock signals; synthesizing local clock signals of which frequencies are regulated into at least two paths of clock signals at the same phase and different frequencies, wherein one path of clock signals is transmitted to the Ethernet interface, while the other at least one path of clock signals is transmitted to Ethernet; and dividing the clock signals received by the Ethernet interface into two paths, wherein one path of clock signals is used as a personal working clock, while the other path of clock ...

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01-08-2007 дата публикации

System and method of automatic phase-locking tracking clock synchronization

Номер: CN0101009544A
Автор: HE YUDONG, YUDONG HE
Принадлежит:

The invention relates to a system and method for locking phase and tracing the time synchronization, the said system includes: the receiver of clock source which is used to receive the second impulse signal and state data of clock source; control device for clock phase-lock which is connected with the receiver of clock source, read the state data of clock source and analyses it to choose a route to trace the second impulse signal, and the traced signal is output according to the need of user. Said method includes: a. receiving the second impulse signal from the clock source and state data; b. analyzing the state data of clock source, and according to the analyzed result choose the second impulse signal; c. tracing the second impulse signal by locking phase and output the signal according to need frequence of user. To solve the problem that caused by using the receiving unit of ''Dipper No. 1'' need to provide local parameters which is lack by hand; and at the same time, it solves the unreliable ...

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20-07-2021 дата публикации

Spraying tooling of motor vehicle wheel hub

Номер: US0011065637B2

A spraying tooling of a motor vehicle wheel hub is provided. The spraying tooling includes an assembly line, multiple wheel hub bases each capable of moving on the assembly line, multiple driving mechanisms each capable of driving a wheel hub base to rotate at a preset position on the assembly line, multiple triggering components each capable of triggering a driving mechanism to operate, multiple maintaining components each capable of maintaining a preset time for a triggering component, and a control component; the wheel hub base includes a sliding seat capable of moving on the assembly line and a tray capable of rotating along with rotation of the driving mechanism, and the tray is rotatably mounted on the sliding seat; and all of the driving mechanisms and the triggering components are electrically connected to the control component.

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04-04-2023 дата публикации

Natural plant essential oil mosquito repellent and preparation method thereof

Номер: CN115886042A
Принадлежит:

The invention belongs to the technical field of pesticides, and particularly relates to a natural plant essential oil mosquito repellent and a preparation method thereof. The invention provides a natural plant essential oil mosquito repellent. The natural plant essential oil mosquito repellent comprises the following components in parts by mass: 1-10 parts of citionella oil, 1-20 parts of clove oil, 1-10 parts of artemisia apiacea oil, 10-60 parts of menthol, 10-20 parts of a surfactant, 1-10 parts of an effect prolonging agent and 300-450 parts of alcohol. In the invention, the mosquito repellent is prepared by taking the plant essential oil as a raw material, has no toxic or side effect and stimulation effect on a human body, and has no pollution to the environment; the repellent effect generated by the medicinal plant essential oil can prevent mosquito bites, so that the spread of entomophilous diseases is reduced, and the compound of various plant essential oils has excellent mosquito ...

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25-04-2012 дата публикации

Method and device for switching clock integrated circuit boards

Номер: CN0101667905B
Автор: HE YUDONG, YUDONG HE
Принадлежит:

The invention discloses a method and a device for switching clock integrated circuit boards. The method comprises the following steps: a first clock integrated circuit board and a second clock integrated circuit board send heartbeat signals and working state information to each other through a communication interface between the integrated circuit boards; and the first clock integrated circuit board and the second clock integrated circuit board determine whether to initiate active-standby status switching according to the heartbeat signals, the active and standby statuses and the working state information of the two clock integrated circuit boards, and send enabling signals to each other through a two-computer logical connection interface between the first clock integrated circuit board and the second clock integrated circuit board so that the active and standby statues of the first clock integrated circuit board and the second clock integrated circuit board are maintained to be mutually ...

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17-08-2005 дата публикации

Clock signal detection method and apparatus in electronic devices

Номер: CN0001655454A
Принадлежит:

This invention provides an electron device clock testing method, which comprises the following steps: determining the said CPU interval terminal signals and inputting the tested clock signal into the interval end of the said CPU; triggering the said tested clock signals for testing according to the interval signal. The invention provides an electron clock test device, which comprises clock input module, triggering module and clock signal test module. íí ...

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07-04-2010 дата публикации

Clock phase-locked method to extract synchronous clock of global positioning system and clock phase-locked loop

Номер: CN0101179371B
Автор: YUDONG HE, HE YUDONG
Принадлежит:

The invention discloses a synchronous clock phase-locking method for extracting synchronous clock of global positioning system. The invention is used for capturing test signals from global positioningsystem module with a output frequency ranging of 500Hz to 1MHz, capturing compared clock signals synchronous with the local clock signals, detecting phase of the test signals and the compared clock signals, and adjusting the frequency of local clock signal according to the phase detection results so that the compared clock signals are synchronous with the test signals. By adopting the method, theclock phase-locking ring disclosed by the invention can quickly lock the synchronous clock of the global positioning system. The invention adopts the high-frequency clock signals as the reference clock, thereby reducing the difficulty in designing the frequency division circuit, shortening the phase-locking time of the clock phase-locking ring and saving a large quantity of hardware resources.

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14-08-2018 дата публикации

Picture display board

Номер: USD825659S
Автор: HE YUDONG, He, Yudong
Принадлежит: HE YUDONG, He Yudong

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22-10-2020 дата публикации

WHEEL HUB MOLDING AND CASTING DIE AND PREPARATION PROCESS THEREOF

Номер: US20200331056A1
Принадлежит:

The present disclosure relates to a wheel hub molding and casting die and a preparation process thereof. The die includes: a casting die shell, a supporting bottom plate, a limiting bottom plate, a lifting module, a module supporting plate, a lower die, an upper die and removable plates. The supporting bottom plate is mounted on the lower surface of the casting die shell. The limiting bottom plate is arranged below the supporting bottom plate. The module supporting plate is movably arranged in a molding cavity. The lifting module is connected between the bottom of the molding cavity and the module supporting plate. The lower die and the upper die are closed to form a pouring cavity. Annular slots are formed in the outer side wall of the upper die. Removable plate slots are formed in the upper surface of the casting die shell. 1. A wheel hub molding and casting die , comprising: a casting die shell , a supporting bottom plate , a limiting bottom plate , a lifting module , a module supporting plate , a lower die , an upper die and removable plates , whereinthe supporting bottom plate is tightly mounted on the lower surface of the casting die shell;the limiting bottom plate is arranged below the supporting bottom plate, and is used to support and limit the casting die shell and the supporting bottom plate;a molding cavity is formed in the middle part of the upper surface of the casting die shell; the lower end of the lifting module is mounted at the middle position of the bottom of the molding cavity; the upper end of the lifting module is mounted at the middle part of the lower surface of the module supporting plate; the module supporting plate is movably arranged in the molding cavity; and the lifting module is used to push the module supporting plate to move;both the lower die and the upper die are of detachable structures; the lower die is mounted at the middle part of the upper surface of the module supporting plate; the upper die is arranged on the outer side of ...

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04-06-2008 дата публикации

Application of brucea javanica oil in preparing medicine for treating chronic gastritis and atrophic gastritis diseases

Номер: CN0101190244A
Автор: HE YUDONG, YUDONG HE
Принадлежит:

The invention relates to the medicine technical field, in particular to an application of brucea oil in preparing the drugs for treating chronic gastritis and atrophic gastritis. Brucea oil is widely applied as an anticancer drug and the safty for oral administration can be proved, so the invention is safe and reliable.The brucea of the quassia has wide source and so the cost is low; through the experiment, the brucea oil performs very well, the treatment effect is ideal and patients can be cured by taking according to the course of treatment without recurrence easily.

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31-01-2012 дата публикации

Methods for diagnosis and/or prognosis of colon cancer

Номер: US0008105777B1

The present invention relates to genetic markers whose expression is correlated with colon cancer. In one aspect, the invention provides sets of markers whose expression can be used for classifying colon cancer patients into different prognostic categories. In another aspect, the invention provides kits containing marker sets for determining prognosis of colon cancer. In another aspect, the invention provides methods of classifying cancer patients with regard to prognosis.

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20-05-2009 дата публикации

Solid cleaning agent and preparation thereof

Номер: CN0101434892A
Автор: HE YUDONG, YUDONG HE
Принадлежит:

The invention discloses a solid cleaning agent and a prepration method thereof, the solid cleaning agent consists of the following components by mass percentage: 12 precent-18 percent of stearic acid, 5 percent-8 percent of monoglyceride, 3 percent-5 percent of TX-10 active agent, 3 percent-5 percent of AE0-9 active agent, 5 percent-8 percent of 6501 active agent, 1 percent-3 percent of triethanolamine, 1 percent-3 percent of ethylene glycol butyl ether, 2 percent-4 percent of JFC penetrant, 1 percent-3 percent of caustic soda, 0.1 percent-0.5 percent of methyl paraben, 0.1 percent-0.5 percent of ethyl paraben and the balance of water. The invention has the advantages that raw materials are easy to be obtained, the production cost is low, and leather or metal surface after cleaning has good light perception without residual impurities.

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08-07-2015 дата публикации

Flue gas desulfurization absorption system

Номер: CN104759199A
Принадлежит:

The invention discloses a flue gas desulfurization absorption system which comprises a desulfurization absorption column, a plurality of flues and a draft fan. A gas outlet is arranged on the top of the desulfurization absorption column. A plurality of flue gas inlets are arranged on the middle part of a side surface of the desulfurization absorption column. The outlet of the draft fan is communicated with the inlets of the flues. The outlets of the flues are respectively communicated with the flue gas inlets on the desulfurization absorption column. An adjusting-type baffle is arranged on each flue. The system can effectively solve a problem of non-uniform distribution of the flue gas in the desulfurization absorption column, is high in desulfurization efficiency and can solve a problem of solid deposition in a slurry material at the inlet of the flue gas inlets on the desulfurization absorption column.

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07-04-2009 дата публикации

Diagnosis and prognosis of breast cancer patients

Номер: US0007514209B2

The present invention relates to genetic markers whose expression is correlated with breast cancer. Specifically, the invention provides sets of markers whose expression patterns can be used to differentiate clinical conditions associated with breast cancer, such as the presence or absence of the estrogen receptor ESR1, and BRCA1 and sporadic tumors, and to provide information on the likelihood of tumor distant metastases within five years of initial diagnosis. The invention relates to methods of using these markers to distinguish these conditions. The invention also relates to kits containing ready-to-use microarrays and computer software for data analysis using the statistical methods disclosed herein.

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13-09-2011 дата публикации

Classification of breast cancer patients using a combination of clinical criteria and informative genesets

Номер: US0008019552B2

The present invention provides prognostic methods for conditions such as cancer, for example, breast cancer, comprising classifying an individual by a plurality of phenotypic, genotypic or clinical characteristics of the condition into a plurality of patient subsets, and analyzing the pattern of expression of prognosis-informative genes identified for that subset in a sample from the individual. The present invention also provides methods for constructing such patient subsets and of identifying prognosis-informative genesets for such subsets. The invention further provides methods of assigning a therapeutic regimen to an individual, microarrays useful for performing prognosis, kits comprising these microarrays, and computer systems and programs for implementing the methods of the invention.

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02-12-1998 дата публикации

Reversing controlling device of concrete conveying pump

Номер: CN0002299167Y
Автор: HE YUDONG, YUDONG HE

The utility model relates to a reversing controlling device of a concrete conveying pump, belonging to the field of the engineering building machine. A minitype piston cylinder with double actions, double bars, and equal area on both ends and a back valve with the throttling action is parallelly connected with a main concrete pumping cylinder via two oil tubes < 11 >. A non-contact proximity switch < 1 > is arranged on the assembly via an installing plate < 2 >. The material sucking character, volume efficiency, pumpability of the concrete pump can be improved. The shock of a system, temperature rise, and power consumption can be reduced. The service life and operational reliability of the proximity switch < 1 > can be improved.

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23-12-2015 дата публикации

Wet flue gas desulfurization system of gas / steam -operating atomizing disperse type

Номер: CN0204891593U
Принадлежит:

The utility model discloses a wet flue gas desulfurization system of gas / steam -operating atomizing disperse type, including desulfurization absorption tower, oxidation fan, slurry circulating pump and be arranged in carrying compressed air or the pipeline of the vapours of drawing forth from drawing gas of thermodynamic system, be equipped with the thick liquid pond in proper order from going in the desulfurization absorption tower, hold the liquid layer and a plurality of layer sprays the layer, the top on desulfurization absorption tower is equipped with the exhanst gas outlet, the side on desulfurization absorption tower is equipped with the flue gas entry, and the flue gas entry is located and holds between liquid layer and the thick liquid pond, the air outlet of oxidation fan is linked together with the thick liquid pond, the thick liquid pond is linked together through slurry circulating pump and the atomizing nozzle that each layer sprayed in the layer, the atomizing nozzle that ...

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04-06-2008 дата публикации

Medicine for treating chronic gastritis

Номер: CN0101190245A
Автор: HE YUDONG, YUDONG HE
Принадлежит:

The invention relates to the field of Chinese traditional medicine technology, in particular to a medicine used for treating chronic gastritis. The invention aims at overcoming the problems of poor treatment effect and easy recurrence existing in the prior art by providing the medicine used for treating chronic gastritis. The technical proposal of the invention for overcoming the problems existing in the prior art is that: the medicine used for treating chronic gastritis is characterized in that the active ingredient thereof consists of brucea javanica oil and seabuckthorn oil and the proportion by weight is that: the brucea javanica oil : the seabuckthorn oil equals to 1: 1 to 8. The medicine includes various preparation forms such as soft capsules, oral emulsion, capsules, granules, tablets, injection, etc.

Подробнее
24-09-2009 дата публикации

Prognosis of breast cancer patients

Номер: US2009239214A1
Принадлежит:

The present invention relates to sets of genetic markers whose expression is correlated with prognosis of breast cancer in individuals having breast cancer. Specifically, the invention provides sets of markers whose expression patterns can be used to differentiate individuals having a good prognosis, e.g., no reoccurrence or metastasis within five years of initial diagnosis, and individuals having a poor prognosis, e.g., reoccurrence or metastasis within five years of initial diagnosis. The invention relates to methods of prognosis using these markers. The invention also relates to microarrays containing probes to these markers, and to kits containing ready-to-use microarrays and computer software for data analysis using the prognostic and statistical methods disclosed herein.

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01-04-2015 дата публикации

High-dynamic weak-compounding code spread spectrum signal fast capturing method

Номер: CN104485976A
Принадлежит:

The invention discloses a high-dynamic weak-compounding code spread spectrum signal fast capturing method, and relates to the technical field of wireless test control communication. Medium-frequency analog signals are subjected to ADC (analog to digital converter) sampling to obtain digital signals, the digital signals are sent into multiple frequency channel processing units, each frequency channel processing unit adopts an FFT (fast Fourier transform) algorithm based on coherent accumulation for traversing inner codes and outer codes to obtain relevant results, finally, relevant results of all frequency channel processing units are detected and judged, and code phase and Doppler frequency information are obtained. The high-dynamic weak-compounding code spread spectrum signal fast capturing method has the advantages that the pseudo code fast capturing and carrier wave estimation in complicated channel environment can be realized, according to the M*M compounding features of the composite ...

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25-07-2012 дата публикации

Device and method for realizing clock synchronization

Номер: CN0101686120B
Автор: YUDONG HE, HE YUDONG
Принадлежит:

The invention relates to a device and a method for realizing clock synchronization. The device comprises an Ethernet interface, a phase-locked loop unit and a clock generation unit, wherein the phase-locked loop unit comprises a logic control circuit, a microprocessor, a digital-to-analogue converter and a voltage controlled oscillator or a direct digital frequency synthesizer. The method comprises the following steps: extracting clock signals; performing phase-locked loop processing on the clock signals; synthesizing local clock signals of which frequencies are regulated into at least two paths of clock signals at the same phase and different frequencies, wherein one path of clock signals is transmitted to the Ethernet interface, while the other at least one path of clock signals is transmitted to Ethernet; and dividing the clock signals received by the Ethernet interface into two paths, wherein one path of clock signals is used as a personal working clock, while the other path of clock ...

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23-05-2023 дата публикации

Electroslag mixing method for inhibiting burning loss of boron element in boron-containing and nitrogen-containing heat-resistant steel

Номер: CN116144937A
Принадлежит:

The invention discloses an electroslag mixing method for inhibiting burning loss of boron in boron-containing and nitrogen-containing heat-resistant steel, which comprises the following steps: adding electroslag mixed slag into a heat-resistant steel ingot, the electroslag mixed slag comprising boron nitride and carbon powder; the protective atmosphere is adopted for electroslag remelting, the filling ratio d is equal to (0.6-0.8) D, and D is the diameter of a crystallizer; and the melting speed of the electroslag is controlled to be 7-11 kg/min. According to the method, electroslag remelting voltage, current and melting speed setting is optimized according to the steel grade characteristics, the steel billet specification and the filling ratio. The melting speed is properly reduced for large-size and large-packing-ratio steel billets, so that composition segregation is inhibited. According to burning loss of the B element, full-flow process optimization is carried out, the B receiving ...

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01-08-2023 дата публикации

Positioning method for embedded foundation bolt of steel structure stand column

Номер: CN116517310A
Принадлежит:

The invention discloses a positioning method for an embedded foundation bolt of a steel structure stand column. The problem that the positioning precision is low when the foundation bolt is embedded on a cast-in-place concrete foundation is solved. Comprising a concrete foundation pit (7) and a rectangular frame (1) made of flat steel plates, and a steel bar net rack (10) is arranged in the concrete foundation pit; foundation bolt penetrating through holes (3) are formed in the four top corners of the rectangular frame (1), embedded foundation bolts (2) are connected in the foundation bolt penetrating through holes (3) in a penetrating mode, lower locking nuts (5) are connected to the embedded foundation bolts (2) below the rectangular frame (1) in a threaded mode, and upper locking nuts (4) are connected to the embedded foundation bolts above the rectangular frame in a threaded mode. The rectangular frame is horizontally arranged right above a steel bar net rack (10), and the lower locking ...

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30-06-2023 дата публикации

Novel blade steel 2Cr12Ni4Mo3VNbN thermal deformation method

Номер: CN116351996A
Принадлежит:

The invention discloses a novel blade steel 2Cr12Ni4Mo3VNbN thermal deformation method, which is characterized in that the heating temperature, the heating rate, the thermal deformation variable in the thermal deformation process and the subsequent heat treatment process control technology are adopted for smelted blade steel to refine grains, the grain size of the obtained blade steel 2Cr12Ni4Mo3VNbN after thermal deformation is controlled to be 7-8 grade, and the grain size is controlled to be 7-8 grade. The comprehensive mechanical property of the steel subjected to thermal treatment after deformation completely meets the technical requirements of high strength and high impact toughness, so that the problems that the steel cracks due to an improper thermal deformation process or the tensile property does not meet the technical requirements of users due to too thick grains are solved; technical support is provided for localization of the steel, the technical bottleneck problem of the steel ...

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14-04-2023 дата публикации

Concentration system and method for advanced treatment of desulfurization wastewater

Номер: CN115959734A
Принадлежит:

The invention discloses a concentration system and method for advanced treatment of desulfurization wastewater, a lime emulsification box is arranged in an inner cavity of a lime slurry box, a desulfurization wastewater interlayer is formed between the outer wall of the lime emulsification box and the inner wall of the lime slurry box, and the upper parts of the desulfurization wastewater interlayer and the lime emulsification box are provided with a water vapor collecting pipeline for collecting water vapor; an outlet of the water vapor collecting pipeline is connected with a heat inlet of the desulfurization wastewater inlet heat exchanger; an outlet of the desulfurization wastewater inlet system is connected with a cold inlet of the desulfurization wastewater inlet heat exchanger; a cold outlet of the desulfurization wastewater inlet heat exchanger is communicated with the desulfurization wastewater interlayer; an outlet of the lime powder supply system is connected to the lime emulsification ...

Подробнее
04-01-2011 дата публикации

Diagnosis and prognosis of breast cancer patients

Номер: US0007863001B2

The present invention relates to genetic markers whose expression is correlated with breast cancer. Specifically, the invention provides sets of markers whose expression patterns can be used to differentiate clinical conditions associated with breast cancer, such as the presence or absence of the estrogen receptor ESR1, and BRCA1 and sporadic tumors, and to provide information on the likelihood of tumor distant metastases within five years of initial diagnosis. The invention relates to methods of using these markers to distinguish these conditions. The invention also relates to kits containing ready-to-use microarrays and computer software for data analysis using the statistical methods disclosed herein.

Подробнее
06-10-2009 дата публикации

Methods for using co-regulated genesets to enhance detection and classification of gene expression patterns

Номер: US0007599799B2

The present invention provides methods for enhanced detection of biological response patterns. In one embodiment of the invention, genes are grouped into basis genesets according to the co-regulation of their expression. Expression of individual genes within a geneset is indicated with a single gene expression value for the geneset by a projection process. The expression values of genesets, rather than the expression of individual genes, are then used as the basis for comparison and detection of biological response with greatly enhanced sensitivity. In another embodiment of the invention, biological responses are grouped according to the similarity of their biological profile. The methods of the invention have many useful applications, particularly in the fields of drug development and discovery. For example, the methods of the invention may be used to compare biological responses with greatly enhanced sensitivity. The biological responses that may be compared according to these methods ...

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08-12-2011 дата публикации

DIAGNOSIS AND PROGNOSIS OF BREAST CANCER PATIENTS

Номер: US20110301048A1

The present invention relates to genetic markers whose expression is correlated with breast cancer. Specifically, the invention provides sets of markers whose expression patterns can be used to differentiate clinical conditions associated with breast cancer, such as the presence or absence of the estrogen receptor ESR1, and BRCA1 and sporadic tumors, and to provide information on the likelihood of tumor distant metastases within five years of initial diagnosis. The invention relates to methods of using these markers to distinguish these conditions. The invention also relates to kits containing ready-to-use microarrays and computer software for data analysis using the statistical methods disclosed herein.

Подробнее
07-07-2023 дата публикации

Positioning method of positioning mechanism for reserved steel sleeve on cast-in-place floor plate of high-rise building

Номер: CN116397904A
Принадлежит:

The invention discloses a positioning method of a positioning mechanism for a reserved steel sleeve on a cast-in-place floor plate of a high-rise building, and solves the problem of how to develop a steel sleeve accurate positioning mechanism to determine the central position of each floor plate hole by using the same positioning datum line and realize accurate positioning of reserved holes between floors. Belongs to the technical field of formworks in civil engineering, and comprises a poured basement floor bottom plate (1) and a first floor plate pouring bottom formwork (6), a datum point (2) perpendicular to the central axis of a drainage pipe is arranged on the basement floor bottom plate (1), and a central positioning through hole (7) of a first embedded steel sleeve is formed in the first floor plate pouring bottom formwork (6). The same vertical infrared ray is adopted as a reference and penetrates through the hollow bolts arranged on the floor formworks to position the steel sleeves ...

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07-04-2023 дата публикации

Desulfurized gypsum vacuum dehydration system and working method thereof

Номер: CN115925293A
Принадлежит:

The invention discloses a desulfurized gypsum vacuum dehydration system and a working method thereof, a gypsum slurry outlet of a gypsum cyclone is connected with a gypsum cyclone underflow pipeline, and the gypsum cyclone underflow pipeline is divided into two paths which are respectively connected with gypsum slurry inlets of a disc dehydrator and a vacuum belt dehydrator; a gypsum slurry inlet of the gypsum cyclone is connected with a gypsum slurry discharge pipeline, a first online flowmeter is arranged on the gypsum slurry discharge pipeline, and a gypsum discharge pump is further arranged on the gypsum slurry discharge pipeline; an overflow liquid outlet of the gypsum cyclone is provided with a second online flowmeter, an underflow pipeline of the gypsum cyclone is provided with a first online densimeter, and the first branch and the second branch are respectively provided with a first control valve and a second control valve; and the on-line flow meter, the on-line densitometer, ...

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16-07-2014 дата публикации

Controllable steam generation device

Номер: CN103925586A
Принадлежит:

A controllable steam generation device comprises a mini-type water feed pump, a steam generation pipe, a heating device and a steam bearing device. The mini-type water feed pump is provided with silicone pipes of different specifications in a matched mode; one end of each silicone pipe is connected with a pure water storage tank; the other end of each silicone pipe is connected with the steam generation pipe; the steam generation pipe is a stainless steel coiled pipe; the heated part is arranged in the heating device, fed water is completely evaporated by being heated, and produced steam enters a mixing tank and is fed into a steam utilization device through the steam bearing device; a steam pipeline, a steam bearing pipeline and the mixing tank are respectively provided with a heat tracing device. The controllable steam generation device has the advantages of being convenient to install, easy to operate, controllable in flow and temperature and the like, meets the supply requirement of ...

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24-06-2015 дата публикации

Efficient dual-circular turn-back absorption tower

Номер: CN104722192A
Принадлежит:

The invention discloses an efficient dual-circular turn-back absorption tower. The absorption tower comprises a primary circular reaction region and a secondary circular reaction region, wherein the primary circular reaction region comprises an absorption tower inlet, a primary circular reaction region pulp pond, a primary circular reaction region pulp supply pump connected with the primary circular reaction region pulp pond, and a primary circular reaction region circulating pump; a primary circular reaction region spraying layer arranged at the upper part of the primary circular reaction region is connected with the primary circular reaction region circulating pump; the secondary circular reaction region comprises an absorption tower outlet, a secondary circular reaction region pump pond, a secondary circular reaction region pulp supply pump connected with the secondary circular reaction region pulp pond, and a secondary circular reaction region circulating pump, a secondary circular ...

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24-12-2020 дата публикации

SPRAYING TOOLING OF MOTOR VEHICLE WHEEL HUB

Номер: US20200398298A1
Принадлежит:

A spraying tooling of a motor vehicle wheel hub is provided. The spraying tooling includes an assembly line, multiple wheel hub bases each capable of moving on the assembly line, multiple driving mechanisms each capable of driving a wheel hub base to rotate at a preset position on the assembly line, multiple triggering components each capable of triggering a driving mechanism to operate, multiple maintaining components each capable of maintaining a preset time for a triggering component, and a control component; the wheel hub base includes a sliding seat capable of moving on the assembly line and a tray capable of rotating along with rotation of the driving mechanism, and the tray is rotatably mounted on the sliding seat; and all of the driving mechanisms and the triggering components are electrically connected to the control component. 1. Spraying tooling of a motor vehicle wheel hub , the spraying tooling comprising an assembly line , a plurality of wheel hub bases each capable of moving on the assembly line , a plurality of driving mechanisms each capable of driving a wheel hub base to rotate at a preset position on the assembly line , a plurality of triggering components each capable of triggering a driving mechanism to operate , a plurality of maintaining components each capable of maintaining a preset time for a triggering component , and a control component; wherein the wheel hub base comprises a sliding seat capable of moving on the assembly line and a tray capable of rotating along with rotation of the driving mechanism , and the tray is rotatably mounted on the sliding seat; and all of the driving mechanisms and the triggering components are electrically connected to the control component.2. The spraying tooling of the motor vehicle wheel hub according to claim 1 , wherein a bottom of the tray comprises a rotating shaft claim 1 , an end of the rotating shaft is fixed to a bottom of the tray claim 1 , another end of the rotating shaft is rotatably mounted ...

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24-06-2009 дата публикации

Method and circuit for eliminating two-shipper control circuit dithering

Номер: CN0101465670A
Принадлежит:

The invention provides a method of eliminating jitter of dual computer control circuit and a jitter elimination circuit. the jitter elimination circuit comprises a jitter judgment unit and a first signal output unit; wherein, the jitter judgment unit is used for judging if the state indication signal of a circuit board has jitter according to the dual computer switching signal and the state indication signal of the circuit board, and outputting a jitter elimination control signal; the first signal output unit is used for selecting the state indication signal of the circuit board or a forced signal of a forced circuit board in primary state to be used as the first signal output according to the jitter elimination control signal output by the jitter judgment unit; the first signal is used for determine the primary and spare states of the circuit board again. Based on the circuit and method in the invention, the jitter of the state indication signal of a primary circuit board can be eliminated ...

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22-10-2002 дата публикации

Methods for using-co-regulated genesets to enhance detection and classification of gene expression patterns

Номер: US0006468476B1

The present invention provides methods for enhanced detection of biological response patterns. In one embodiment of the invention, genes are grouped into basis genesets according to the co-regulation of their expression. Expression of individual genes within a geneset is indicated with a single gene expression value for the geneset by a projection process. The expression values of genesets, rather than the expression of individual genes, are then used as the basis for comparison and detection of biological response with greatly enhanced sensitivity. In another embodiment of the invention, biological responses are grouped according to the similarity of their biological profile. The methods of the invention have many useful applications, particularly in the fields of drug development and discovery. For example, the methods of the invention may be used to compare biological responses with greatly enhanced sensitivity. The biological responses that may be compared according to these methods include responses to single perturbations, such as a biological response to a mutation or temperature change, as well as graded perturbations such as titration with a particular drug. The methods are also useful to identify cellular constituents, particularly genes, associated with a particular type of biological response. Further, the methods may also be used to identify perturbations, such as novel drugs or mutations, which effect one or more particular genesets. The methods may still further be used to remove experimental artifacts in biological response data.

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25-10-2018 дата публикации

DIAGNOSIS AND PROGNOSIS OF BREAST CANCER PATIENTS

Номер: US20180305768A1

The present invention relates to genetic markers whose expression is correlated with breast cancer. Specifically, the invention provides sets of markers whose expression patterns can be used to differentiate clinical conditions associated with breast cancer, such as the presence or absence of the estrogen receptor ESR1, and BRCA1 and sporadic tumors, and to provide information on the likelihood of tumor distant metastases within five years of initial diagnosis. The invention relates to methods of using these markers to distinguish these conditions. The invention also relates to kits containing ready-to-use microarrays and computer software for data analysis using the statistical methods disclosed herein.

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15-06-2011 дата публикации

Time clock phase locking loop controlling method and apparatus

Номер: CN0101420294B
Автор: HE YUDONG, YUDONG HE
Принадлежит:

The present invention provides a clock phase-locked loop control method and a device thereof. The device comprises a phase reference clock source for outputting phase reference clock signals with a predetermined phase; a phase discriminator for discriminating phases of the clock signals output by the clock driver and the phase reference clock signals; a processor for outputting control parametersaccording to a frequency phase discrimination value output by the frequency phase discriminator and a phase discrimination value output by the phase discriminator; a local clock control source for outputting clock signals having the same frequency with clock signals output by the frequency reference clock source and having the same phase with the phase reference clock signals according to controlparameters, thus, the phase of output clock signals can be controlled under the condition that the frequency of clock signals output by the local clock control source is the same as that of the clocksignals ...

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15-10-2014 дата публикации

Synergistic removal system and method for realizing ultra-low emission of multiple pollutants of smoke of thermal power plant

Номер: CN104100964A
Принадлежит:

The invention discloses a synergistic removal system and method for realizing ultra-low emission of multiple pollutants of smoke of a thermal power plant. By the aid of a synergistic dust-removal system consisting of a smoke cooler, an efficient dust remover, an efficient wet desulphurization system and a wet type electric dust remover, the total particulate matter emission in a chimney can be controlled within 5 mg/m<3>. By the aid of a synergistic mercury-removal system consisting of a selective catalytic reduction denitration system, the efficient dust remover, the efficient wet desulphurization system and the wet type electric dust remover, the emission concentration of mercury in the smoke at the chimney can be lower than 6 mu g/m<3>. By the aid of an efficient denitration system consisting of a low-nitrogen burner, a selective non-catalytic reduction denitration system and the selective catalytic reduction denitration system, the NOx concentration can be controlled within 50 mg/m< ...

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08-09-2010 дата публикации

Phase discriminator, phase demodulation method and phase-locked loop

Номер: CN0101299609B
Автор: HE YUDONG, YUDONG HE
Принадлежит:

The invention discloses a phase discriminator for receiving the reference clock signal and the local pulse clock signal, including a frequency division module for performing the two divided-frequency to the received reference clock signal and outputting the two divided-frequency signal; a time delay module, for delaying the two divided-frequency signal and outputting the time delay signal, wherein the delay time is a local pulse clock period; a phase discrimination module for receiving the two divided-frequency signal and the time delay signal using the local pulse clock signal as the count clock, counting the local pulse clock signal in the time slot of the high level pulse width or the low level pulse width and starting counting again. The invention also discloses a phase discriminationmethod and a locking ring. The phase discriminator and the phase discrimination method have no specific requirement on the input signal frequency, directly judge the correctness of the phase discrimination ...

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27-05-2015 дата публикации

Magnetic photo combination board

Номер: CN104643750A
Автор: HE YUDONG
Принадлежит:

The invention relates to a magnetic photo combination board. The magnetic photo combination board comprises a bottom board, wherein a plurality of bumps are distributed on the front face of the bottom board; a plurality of metal covers which can be attracted with magnets can be arranged on the bottom boards through the bumps on the bottom board one by one; the adjacent metal covers are spliced together to form an entire body; the cover face of each metal cover forms a hanging and sticking face capable of hanging and sticking a photo; the photos to be hung and stuck to the cover faces of the metal covers by magnetic pieces; the adjacent metal covers can be mutually plugged, so that the metal covers are spliced together to form the entire body. The photo combination board is formed by the bottom board and the metal covers, so that the photos can be hung or stuck to the combination board in an ordered or random manner through the magnets attracted on the metal covers; therefore, one combination ...

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02-05-2023 дата публикации

Sulfur trioxide measuring device and method

Номер: CN116046991A
Принадлежит:

The invention discloses a sulfur trioxide measuring device and method.The sulfur trioxide measuring device comprises a box suitable for introducing an ice-water mixture, two sampling devices, a supporting plate and an adjusting assembly, two mounting holes are formed in the top wall of the box, and the two sampling devices are inserted into the box through the two mounting holes respectively; the two sampling devices are communicated with each other, one of the two sampling devices is suitable for collecting sulfur trioxide gas for the first time, the other sampling device is suitable for collecting sulfur trioxide gas for the second time, the supporting plate is arranged in the box body and connected with the two sampling devices, and the adjusting assembly is connected with the box body and the supporting plate so as to adjust the position height of the supporting plate relative to the box body. The sulfur trioxide measuring device provided by the invention has the advantage of strong ...

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10-06-2015 дата публикации

Magnetic photo combined board

Номер: CN104687901A
Автор: HE YUDONG
Принадлежит:

The invention discloses a magnetic photo combined board. The magnetic photo combined board is characterized by comprising a plurality of metal covers, support parts and magnetic parts, each metal cover is provided with a cover surface, the front side of the cover surface forms a put-up side used for putting up photos, the photos are put up on the cover surface through the magnetic parts, and the support parts are supported on the back of the metal covers. Each metal cover and the support parts are detachably connected via first connecting structures to form frame units, and the adjacent frame units are detachably connected and combined via second connecting structures. The photos can be orderly or randomly put up on the combined board via the magnets attracted to the metal covers, and the combined boards can be combined in different sizes according to the amount of the photos and can be made into the size small only enough to arrange one to four photos as a small photo frame or big enough ...

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08-08-2023 дата публикации

Laundry detergent for infants and preparation method thereof

Номер: CN116554969A
Принадлежит:

The invention relates to the technical field of laundry detergents, in particular to the field of IPC C11D1, and more specifically relates to a laundry detergent for infants and a preparation method thereof. The shampoo is prepared from the following components: 10 to 20 parts of coconut oil derivative, 5 to 10 parts of plant extract, 0.5 to 2 parts of biological enzyme, 1 to 4 parts of softening factor, 2 to 4 parts of lemon essence, 2 to 4 parts of plant-derived surfactant, 1 to 3 parts of thickening agent, 1 to 2 parts of softening and moistening agent, 1 to 2 parts of macromolecular builder, 0.01 to 0.07 part of preservative and 60 to 100 parts of deionized water. The biological enzyme comprises alkaline protease and alkaline lipase, the weight ratio of the alkaline protease to the alkaline lipase is 1: (0.3-0.6), and the cleaning capacity and the antibacterial performance of the laundry detergent can be further improved.

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09-05-2013 дата публикации

DIAGNOSIS AND PROGNOSIS OF BREAST CANCER PATIENTS

Номер: US20130116145A1
Принадлежит:

The present invention relates to genetic markers whose expression is correlated with breast cancer. Specifically, the invention provides sets of markers whose expression patterns can be used to differentiate clinical conditions associated with breast cancer, such as the presence or absence of the estrogen receptor ESR1, and BRCA1 and sporadic tumors, and to provide information on the likelihood of tumor distant metastases within five years of initial diagnosis. The invention relates to methods of using these markers to distinguish these conditions. The invention also relates to kits containing ready-to-use microarrays and computer software for data analysis using the statistical methods disclosed herein. 160-. (canceled)61. A positionally-addressable array of polynucleotides bound to a support comprising: at least five (5) different means for distinguishing a breast cancer patient with a good prognosis from a breast cancer patient with a poor prognosis.62. The positionally-addressable array of claim 61 , wherein each of the five means for distinguishing a breast cancer patient with a good prognosis from a breast cancer patient with a poor prognosis is a nucleic acid molecule selected from the group consisting of SEQ ID NO:1 claim 61 , SEQ ID NO:37 claim 61 , SEQ ID NO:55 claim 61 , SEQ ID NO:58 claim 61 , SEQ ID NO:62; SEQ ID NO:75 claim 61 , SEQ ID NO:88 claim 61 , SEQ ID NO:120 claim 61 , SEQ ID NO 121 claim 61 , SEQ ID NO:124 claim 61 , SEQ ID NO:137 claim 61 , SEQ ID NO:169 claim 61 , SEQ ID NO:173 claim 61 , SEQ ID NO: 177 claim 61 , SEQ ID NO:183 claim 61 , SEQ ID NO:189 claim 61 , SEQ ID NO: 196 claim 61 , SEQ ID NO:219 claim 61 , SEQ ID NO:257 claim 61 , SEQ ID NO:259 claim 61 , SEQ ID NO:270 claim 61 , SEQ ID NO:271 claim 61 , SEQ ID NO:272 claim 61 , SEQ ID NO:306 claim 61 , SEQ ID NO:307 claim 61 , SEQ ID NO:315 claim 61 , SEQ ID NO:326 claim 61 , SEQ ID NO:327 claim 61 , SEQ ID NO:336 claim 61 , SEQ ID NO:353S SEQ ID NO:357 claim 61 , SEQ ID NO:390 claim ...

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25-06-2001 дата публикации

Methods of using co-regulated gene sets to enhance detection and classification of gene expression patterns

Номер: NO20012036L
Принадлежит: Rosetta Inpharmatics Inc

Den foreliggende oppfinnelse tilveiebringer metoder for forsterket deteksjon av biologiske responsmønstre. l en utførelsesform av oppfinnelsen grupperes gener til basisgensett i samsvar med ko-reguleringen av deres ekspresjon. Ekspresjon av individuelle gener innenfor et gensett indikeres med en enkelt genekspresjonsverdi for gensettet ved hjelp av en projeksjonsprosess. Ekspresjonsverdiene av gensett, snarere enn ekspresjonen av enkeltgener, anvender så som basis for sammenligning og deteksjon av biologisk respons med meget forsterket sensitivitet. I en ytterligere utførelsesform av oppfinnelsen grupperes biologiske responser i samsvar med similariteten av deres biologiske profil. Metodene ifølge oppfinnelsen har mange nyttige anvendelser, spesielt innenfor områdene med legemiddelutvikling og legemiddeloppdagelse. F.eks. kan metodene ifølge oppfinnelsen anvendes for å sammenligne biologiske responser med meget forsterket sensitivitet. De biologiske responser som kan sammenlignes ved hjelp av disse metoder inkluderer responser til enkle perturbasjoner, som f.eks. en biologisk respons til en mutasjon eller temperaturendring, såvel som graderte perturbasjoner som f.eks. titrasjon med et spesielt legemiddel. Metodene er også nyttige for å identifisere cellulære bestanddeler, særlig gener, assosiert med en spesiell type av biologisk respons. Videre kan metodene også anvendes for å identifisere perturbasjoner, som f.eks. nye legemidler eller mutasjoner, som påvirker ett eller flere spesielle gensett. Metodene kan ytterligere anvendes for å fjerne forsøksartefakter i biologiske responsdata.

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02-06-2005 дата публикации

Diagnosis and prognosis of breast cancer patients

Номер: WO2004065545A3

The present invention relates to genetic markers whose expression is correlated with breast cancer. Specifically, the invention provides sets of markers whose expression patterns can be used to differentiate clinical conditions associated with breast cancer, such as the presence or absence of the estrogen receptor ESR1, and BRCA1 and sporadic tumors, and to provide information on the likelihood of tumor distant metastases within five years of initial diagnosis. The invention relates to methods of using these markers to distinguish these conditions. The invention also provides methods of classifying and treating patients based on prognosis. The invention also relates to kits containing ready-to-use microarrays and computer software for data analysis using the diagnostic, prognostic and statistical methods disclosed herein.

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26-01-2006 дата публикации

Classification of breast cancer patients using a combination of clinical criteria and informative genesets

Номер: WO2005086891A9

The present invention provides prognostic methods for conditions such as cancer, for example, breast cancer, comprising classifying an individual by a plurality of phenotypic, genotypic or clinical characteristics of the condition into a plurality of patient subsets, and analyzing the pattern of expression of prognosis-informative genes identified for that subset in a sample from the individual. The present invention also provides methods for constructing such patient subsets and of identifying prognosis-informative genesets for such subsets. The invention further provides methods of assigning a therapeutic regimen to an individual, microarrays useful for performing prognosis, kits comprising these microarrays, and computer systems and programs for implementing the methods of the invention.

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05-08-2004 дата публикации

Diagnosis and prognosis of breast cancer patients

Номер: CA2513642A1
Принадлежит: Individual

The present invention relates to genetic markers whose expression is correlated with breast cancer. Specifically, the invention provides sets of markers whose expression patterns can be used to differentiate clinical conditions associated with breast cancer, such as the presence or absence of the estrogen receptor ESR1, and BRCA1 and sporadic tumors, and to provide information on the likelihood of tumor distant metastases within five years of initial diagnosis. The invention relates to methods of using these markers to distinguish these conditions. The invention also provides methods of classifying and treating patients based on prognosis. The invention also relates to kits containing ready-to-use microarrays and computer software for data analysis using the diagnostic, prognostic and statistical methods disclosed herein.

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06-07-2000 дата публикации

Methods of characterizing drug activities using consensus profiles

Номер: CA2356648A1
Принадлежит: Individual

The present invention provides methods for enhanced detection of biological response profiles. In particular, the methods of this invention allow for the detection of biological response patterns, such as gene expression patterns, in response to different drug treatments. The methods of the invention also allow the determination of a "consensus profile" which describes a particular class or type of biological response. In certain embodiments the consensus profile may describe the biological response of a particular group or class of drugs. In other embodiments, the consensus profile may describe an "ideal" biological response such as one associated with a desired therapeutic effect. The methods of the present invention also allow for the comparison of different biological responses. Thus, the methods of the invention may be used, e.g., to identify and/or study new drugs.

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18-06-2009 дата публикации

Diagnosis and prognosis of breast cancer patients

Номер: US20090157326A1

The present invention relates to genetic markers whose expression is correlated with breast cancer. Specifically, the invention provides sets of markers whose expression patterns can be used to differentiate clinical conditions associated with breast cancer, such as the presence or absence of the estrogen receptor ESR1, and BRCA1 and sporadic tumors, and to provide information on the likelihood of tumor distant metastases within five years of initial diagnosis. The invention relates to methods of using these markers to distinguish these conditions. The invention also relates to kits containing ready-to-use microarrays and computer software for data analysis using the statistical methods disclosed herein.

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09-03-2006 дата публикации

Classification of breast cancer patients using a combination of clinical criteria and informative genesets

Номер: WO2005086891A3

The present invention provides prognostic methods for conditions such as cancer, for example, breast cancer, comprising classifying an individual by a plurality of phenotypic, genotypic or clinical characteristics of the condition into a plurality of patient subsets, and analyzing the pattern of expression of prognosis-informative genes identified for that subset in a sample from the individual. The present invention also provides methods for constructing such patient subsets and of identifying prognosis-informative genesets for such subsets. The invention further provides methods of assigning a therapeutic regimen to an individual, microarrays useful for performing prognosis, kits comprising these microarrays, and computer systems and programs for implementing the methods of the invention.

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09-02-2006 дата публикации

Prognosis of breast cancer patients

Номер: CA2575557A1
Принадлежит: Individual

The present invention relates to sets of genetic markers whose expression is correlated with prognosis of breast cancer in individuals having breast cancer. Specifically, the invention provides sets of markers whose expression patterns can be used to differentiate individuals having a good prognosis, e.g., no reoccurrence or metastasis within five years of initial diagnosis, and individuals having a poor prognosis, e.g., reoccurrence or metastasis within five years of initial diagnosis. The invention relates to methods of prognosis using these markers. The invention also relates to microarrays containing probes to these markers, and to kits containing ready-to-use microarrays and computer software for data analysis using the prognostic and statistical methods disclosed herein.

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04-11-2021 дата публикации

Determining mortality risk of subjects with viral infections

Номер: WO2021222537A1
Принадлежит: Inflammatix, Inc.

Systems, methods, compositions, apparatuses, and kits for determining the 30-day mortality risk of subjects with viral infections, and for determining effective triage strategies for such subjects, are provided herein. The disclosed methods and compositions involve biomarkers identified from the application of a machine learning workflow to viral mortality training data. The biomarkers allow the calculation of a score that can be used to determine the likelihood of 30-day survival in the subjects.

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12-12-2023 дата публикации

Automobile wheel hub shaping device

Номер: US11839912B2
Автор: Libo LIU, Yudong He
Принадлежит: CITIC Dicastal Co Ltd

The present disclosure discloses an automobile wheel hub shaping device. The automobile wheel hub shaping device includes a clamping part for clamping a wheel hub to be shaped, a first driving mechanism for driving the clamping part to rotate, a shaping roller for shaping the wheel hub to be shaped, and a rack; all the clamping part, the first driving mechanism and the shaping roller are mounted to the rack, the shaping roller is located above the clamping part and is capable of rotating relative to the clamping part; and the clamping part is equipped with a fixing part for fixing the wheel hub to be shaped.

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11-01-2024 дата публикации

Methods for diagnosing myocardial infarction

Номер: WO2023192004A3
Принадлежит: Inflammatix, Inc.

Systems, methods, compositions, apparatuses, and kits for determining whether a subject is undergoing myocardial infarction (MI) using biological samples obtained from the subject, are provided herein. The disclosed methods and compositions involve biomarkers identified from the transcriptomic data of biological samples from subjects with MI. The biomarkers allow the calculation of a composite biomarker value that can be used to determine whether the subject is undergoing MI.

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14-02-2024 дата публикации

Methods of diagnosis of respiratory viral infections

Номер: EP4320262A1
Принадлежит: Inflammatix Inc

Systems, methods, compositions, apparatuses, and kits for determining the viral infection status of subjects using respiratory samples, and for determining effective triage strategies for such subjects, are provided herein. The disclosed methods and compositions involve biomarkers identified from the application of a machine learning workflow to viral training data from respiratory samples. The biomarkers allow the calculation of a score that can be used to determine the viral infection status of the subjects.

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05-10-2023 дата публикации

Methods for diagnosing myocardial infarction

Номер: WO2023192004A2
Принадлежит: Inflammatix, Inc.

Systems, methods, compositions, apparatuses, and kits for determining whether a subject is undergoing myocardial infarction (MI) using biological samples obtained from the subject, are provided herein. The disclosed methods and compositions involve biomarkers identified from the transcriptomic data of biological samples from subjects with MI. The biomarkers allow the calculation of a composite biomarker value that can be used to determine whether the subject is undergoing MI.

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08-03-2023 дата публикации

Determining mortality risk of subjects with viral infections

Номер: EP4143343A1
Принадлежит: Inflammatix Inc

Systems, methods, compositions, apparatuses, and kits for determining the 30-day mortality risk of subjects with viral infections, and for determining effective triage strategies for such subjects, are provided herein. The disclosed methods and compositions involve biomarkers identified from the application of a machine learning workflow to viral mortality training data. The biomarkers allow the calculation of a score that can be used to determine the likelihood of 30-day survival in the subjects.

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04-11-2021 дата публикации

Determining mortality risk of subjects with viral infections

Номер: CA3177170A1
Принадлежит: Inflammatix Inc

Systems, methods, compositions, apparatuses, and kits for determining the 30-day mortality risk of subjects with viral infections, and for determining effective triage strategies for such subjects, are provided herein. The disclosed methods and compositions involve biomarkers identified from the application of a machine learning workflow to viral mortality training data. The biomarkers allow the calculation of a score that can be used to determine the likelihood of 30-day survival in the subjects.

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17-11-2022 дата публикации

Determining mortality risk of subjects with viral infections

Номер: AU2021264555A1
Принадлежит: Inflammatix Inc

Systems, methods, compositions, apparatuses, and kits for determining the 30-day mortality risk of subjects with viral infections, and for determining effective triage strategies for such subjects, are provided herein. The disclosed methods and compositions involve biomarkers identified from the application of a machine learning workflow to viral mortality training data. The biomarkers allow the calculation of a score that can be used to determine the likelihood of 30-day survival in the subjects.

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28-10-2020 дата публикации

Wheel hub molding and casting die and preparation process thereof

Номер: EP3730229A1
Автор: Libo LIU, Yudong He
Принадлежит: CITIC Dicastal Co Ltd

The present disclosure relates to a wheel hub molding and casting die and a preparation process thereof. The die includes: a casting die shell, a supporting bottom plate, a limiting bottom plate, a lifting module, a module supporting plate, a lower die, an upper die and removable plates. The supporting bottom plate is mounted on the lower surface of the casting die shell. The limiting bottom plate is arranged below the supporting bottom plate. A molding cavity is formed in the upper surface of the casting die shell. The module supporting plate is movably arranged in the molding cavity. The lifting module is connected between the bottom of the molding cavity and the module supporting plate. The lower die is mounted on the upper surface of the module supporting plate. The upper die is arranged on the outer side of the lower die in a sleeving manner. The lower die and the upper die are closed to form a pouring cavity. Pouring holes are formed in the upper surface of the upper die. Annular slots are formed in the outer side wall of the upper die. Removable plate slots are formed in the upper surface of the casting die shell. The removable plates are arranged on the removable plate slots in a movably limited manner. The removable plates are fitted with the annular slots. The present disclosure can conveniently and quickly take down the upper die from a molded wheel hub and ensure that the upper die does not scrape the molded wheel hub when being taken down from the molded wheel hub. (Fig. 1)

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23-11-2023 дата публикации

Determining mortality risk of subjects with viral infections

Номер: US20230374589A1
Принадлежит: Inflammatix Inc

Systems, methods, compositions, apparatuses, and kits for determining the 30-day mortality risk of subjects with viral infections, and for determining effective triage strategies for such subjects, are provided herein. The disclosed methods and compositions involve biomarkers identified from the application of a machine learning workflow to viral mortality training data. The biomarkers allow the calculation of a score that can be used to determine the likelihood of 30-day survival in the subjects.

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28-10-2020 дата публикации

Matrice de moulage et de coulée pour moyeu de roue et son procédé de préparation

Номер: MA47527A
Автор: Libo LIU, Yudong He
Принадлежит: CITIC Dicastal Co Ltd

Подробнее
29-04-2022 дата публикации

Dispositif de positionement pour un moyeu de roue

Номер: MA47523B1
Автор: Libo LIU, Yudong He
Принадлежит: CITIC Dicastal Co Ltd

L'invention concerne le domaine technique de l'usinage de pièces automobiles, en particulier un dispositif de positionnement d'outil de moyeu de roue. Le dispositif comprend un châssis de machine, un mécanisme d'entraînement, une pompe à air, une pluralité d'éléments de serrage et des ensembles de recul. Chaque élément de serrage comprend un déflecteur, des rainures de stockage et des coussins d'air. Les rainures de stockage sont formées dans l'une des surfaces latérales des déflecteurs, les coussins gonflables sont disposés dans les rainures de stockage et reliés à la pompe à air, et les coussins gonflables font saillie des surfaces latérales des déflecteurs après avoir été gonflés et déployés. Chaque ensemble de recul comprend un bloc de connexion, une tige coulissante, un élément élastique et deux blocs de coussinets ; les deux extrémités de chaque tige coulissante sont chacune connectées au bloc de coussinets correspondant ; les blocs de coussinets sont entraînés par le mécanisme d'entraînement pour se déplacer dans la direction radiale du châssis de la machine ; les blocs de connexion sont disposés de manière coulissante sur les tiges coulissantes en mode manchon ; les éléments élastiques sont disposés sur les tiges coulissantes en mode manchon ; et les extrémités inférieures des déflecteurs sont connectées aux blocs de connexion. Selon le dispositif de fixation de l'outil de positionnement du moyeu de roue, grâce au contact souple entre les coussins gonflables et le moyeu de roue, on évite d'endommager le moyeu de roue en raison d'une contrainte élevée dans le processus de positionnement, le dispositif de fixation peut être appliqué au positionnement du moyeu de roue fait d'un matériau souple en alliage d'aluminium, et les processus de serrage et de démontage sont pratiques.

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29-12-2021 дата публикации

Wheel hub tool positioning fixture

Номер: EP3715046B1
Автор: Libo LIU, Yudong He
Принадлежит: CITIC Dicastal Co Ltd

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04-07-2024 дата публикации

Methods of diagnosis of respiratory viral infections

Номер: US20240218468A1
Принадлежит: Inflammatix Inc

Systems, methods, compositions, apparatuses, and kits for determining the viral infection status of subjects using respiratory samples, and for determining effective triage strategies for such subjects, are provided herein. The disclosed methods and compositions involve biomarkers identified from the application of a machine learning workflow to viral training data from respiratory samples. The biomarkers allow the calculation of a score that can be used to determine the viral infection status of the subjects.

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15-08-2024 дата публикации

Unmanned vehicle scheduling platform, unmanned vehicle, scheduling method and storage medium

Номер: AU2022481274A1
Автор: Yudong He
Принадлежит: Beijing Eacon Technology Co Ltd

Disclosed in the present application are an unmanned vehicle scheduling platform, an unmanned vehicle, a scheduling method and a storage medium, belonging to the technical field of autonomous driving. The scheduling platform determining, within a working area, n excavators, m waste dumps, and at least two unmanned vehicles requiring to execute working tasks cyclically, at least one of n and m being greater than or equal to 2; setting for each unmanned vehicle priority information of the n excavators and/or of the m waste dumps, so as to obtain a cyclic scheduling task list containing the priority information; and sending the cyclic scheduling task list to the unmanned vehicles, so as to enable the unmanned vehicles not to depend on scheduling of the scheduling platform during cyclic execution of the working tasks, and selecting an excavator and/or a waste dump in real time on the basis of the priority information and communication data acquired by means of communication among vehicles, so as to execute the working tasks, the communication data representing the number of unmanned vehicles assigned to each excavator or each waste dump at a current moment. The present application improves the cooperative working efficiency of the unmanned vehicles in the working area.

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03-04-2020 дата публикации

一种用于铝合金轮毂的钻孔工装

Номер: CN210232297U
Принадлежит: CITIC Dicastal Co Ltd

本实用新型公开了一种用于铝合金轮毂的钻孔工装,所述工装包括放置工件的工作台和在所述工作台上方、相对所述工作台上下移动的钻夹头;所述工作台上包括工件装夹座,所述工件装夹座包括至少两个以相同圆心径向分布的夹紧块和给所述夹紧块提供夹紧力的弹性部件;所述夹紧块的内壁设有夹紧所述工件的夹紧面,所述夹紧块的外壁连接所述弹性部件。本实用新型的用于铝合金轮毂的钻孔工装,使装夹效率更高,进而提高加工效率,降低加工成本。

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03-10-2024 дата публикации

A baseline gene expression-based prognostic for anti-inf alpha therapy response ni patients with inflammatory bowel disease

Номер: US20240327918A1
Принадлежит: Inflammatix Inc

Systems, methods, compositions, apparatuses, and kits for determining the responsiveness of subjects with inflammatory bowel disease (IBD) to anti-TNF alpha therapy using biological samples obtained from the subjects, are provided herein. The disclosed methods and compositions involve biomarkers identified from the application of a machine learning workflow to TNF alpha response training data from biological samples. The biomarkers allow the calculation of a score that can be used to determine the TNF alpha responder status of the subjects.

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10-10-2024 дата публикации

Methods for diagnosing myocardial infarction

Номер: AU2023243976A1
Принадлежит: Inflammatix Inc

Systems, methods, compositions, apparatuses, and kits for determining whether a subject is undergoing myocardial infarction (MI) using biological samples obtained from the subject, are provided herein. The disclosed methods and compositions involve biomarkers identified from the transcriptomic data of biological samples from subjects with MI. The biomarkers allow the calculation of a composite biomarker value that can be used to determine whether the subject is undergoing MI.

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09-10-2024 дата публикации

Determining mortality risk of subjects with viral infections

Номер: EP4143343A4
Принадлежит: Inflammatix Inc

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