Derivatives of benzosulphonamides as inhibitors of the enzyme cyclo-oxygenase II

Derivatives of benzosulphonamides as inhibitors of the enzyme cyclo-oxygenase II

PCT No. PCT/EP96/02954 Sec. 371 Date Sep. 3, 1998 Sec. 102(e) Date Sep. 3, 1998 PCT Filed Jul. 5, 1996 PCT Pub. No. WO97/03953 PCT Pub. Date Feb. 6, 1997Compounds of the formula (I) in which A is oxygen, sulphur or NH; B is a group of the formula (IIa) or (IIb); and the other variables have the meaning given in claim 1, may be used as inhibitors of the enzyme cyclooxygenase II

Compositions that mediate killing of hiv-infected cells

A method for directing a cytotoxic T cell to an HIV-I-infected cell, which comprises contacting the infected cell with a bispecific proteinaceous molecule comprising two binding domains, wherein the first binding domain comprises a CD4 domain or domains and the second binding domain comprises an anti-CD3 binding region.

Derivatives of benzosulphonamides as inhibitors of the enzyme cyclo-oxygenase ii

Compounds of the formula (I) in which A is oxygen, sulphur or NH; B is a group of the formula (IIa) or (IIb); and the other variables have the meaning given in claim 1, may be used as inhibitors of the enzyme cyclo-oxygenase II.

BENZOSULFONAMIDE DERIVATIVES AS ENZYME CYCLE-OXYGENASE II INHIBITORS

Pressure control apparatus for adjusting brake pressure in a vehicle

A pressure control apparatus for adjusting the brake pressure in a braking system of a vehicle comprises a reservoir in which a pressure fluid is stored, an outlet through which the pressure fluid is discharged, at least one brake cylinder of the braking system, inlet and outlet valves through which the pressure fluid is supplied to and discharged from the brake cylinder, and a digital controller which controls the opening and closing of the inlet and outlet valves to minimize the deviation between an actual value and a command variable. The digital controller comprises individual controllers associated with the inlet and outlet valves. The individual controllers operate in accordance with a changeable PIDD 2 control formula. The digital control further comprises a three-stage controller connected downstream of the individual controllers and adjustable low pass filters for the inlet and outlet valves. A pressure phase detector determines the current pressure phase to be set (i.e., increase, maintain or decrease) based on the command variable, and adjusts the operation of the individual controllers, the three-stage controller, and the low pass filters based on the current pressure phase.