16-04-2015 дата публикации
Номер: US20150105458A1
Принадлежит:
Preparation and application of line leaf flower lactone A in the multiple sclerosis, having a structure of 2. The pharmaceutical composition according to claim 1 , further comprising a pharmaceutically acceptable carrier claim 1 ,{'i': 'inula', 'wherein the line leaf flower lactone A is a sole active ingredient in the composition.'}3. The pharmaceutical composition according to claim 2 , wherein the pharmaceutical composition is in a form of tablets claim 2 , dispersible tablets claim 2 , mouth collapse tablets claim 2 , retard tablets claim 2 , capsule claim 2 , soft capsule claim 2 , dropping pill claim 2 , granules claim 2 , injection claim 2 , powder injection claim 2 , or aerosol.4. A method for treating multiple sclerosis according to claim 1 , comprising{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'administering a therapeutically effective amount of the pharmaceutical composition of in a subject in need of treatment for multiple sclerosis.'}5. The method for treating multiple sclerosis according to claim 4 , wherein the pharmaceutical composition is administered by intraperitoneal injection or intragastric administration. The subject application is a continuation of PCT international application PCT/CN2012/001411 filed on Oct. 22, 2012, which in turn claims priority on Chinese patent applications CN 201210208157.4 filed on Jun. 21, 2012. The contents and subject matter of the PCT and Chinese priority applications are incorporated herein by reference.The present invention relates to Chinese traditional medicine flowers, specifically, the preparation of lactone A from flowers and its application in the preparation of medicine for treating multiple sclerosis.Since it was first proposed in 1868 by the French doctor Charcot, multiple sclerosis (MS) has been a disease that is still extremely difficult to treat in the world. It is a chronic autoimmune disease that causes myelin destroyed in the brain, spinal cord, and optic nerve fiber layer, at last, affects ...
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