MULTIPLE-FIRING SUTURE FIXATION DEVICE AND METHODS FOR USING AND MANUFACTURING SAME

A multiple-firing clip device includes a hollow shaft defining a lateral opening communicating with an environment and a distal shaft portion between the lateral opening and a distal end opening. A shuttle longitudinally moves on the shaft and comprises a shuttle body defining a lumen surrounding the shaft, a snare, and a snare-extender slide defining a snare track to form a snare travel path in which the snare is disposed from the body and through the track and a portion of the body. The slide moves along a given extent defining a slide distance and a distal end and movement of the slide to the distal end shortens the snare travel path to extend the snare portion through the lateral opening, through the distal shaft portion, and distally out from a distal side of the body longer than the given extent to secure a suture with the snare. 1. A multiple-firing clip device , comprising:a plurality of suture fixation clips each having an internal hollow shaped to receive therein at least one suture;a hollow shaft having a distal fixation location, an exterior surface, a distal shaft end, and an interior; the plurality of the suture fixation clips stacked in the interior, defining a first clip, and configured to move along a longitudinal axis; the shaft defining a lateral opening proximal to the distal fixation location; the lateral opening communicating between the interior and an environment outside the exterior surface;a clip movement assembly within the interior of the shaft and configured to deliver the first clip to the distal fixation location by moving the first clip longitudinally from a first proximal position into the distal fixation location; and a shuttle body comprising a hollow, snare-guiding tube having a distal tube end;', 'a snare operatively connected to the shuttle body and having a distal snare portion; and', 'a snare-extender slide defining a snare track aligned with the snare-guiding tube to form a snare travel path; the snare being disposed within a ...

Spring cannulae

Disclosed herein are embodiments of spring cannulae, including one or more holes in the sidewall of the cannula. Some disclosed cannulae include a wire, helically wound to form coils, and at least one hole in the cannula that interrupts one or more of the coils. Some embodiments further include a fused region of the coils through which the hole passes. Some embodiments include a ring attached to ends of the interrupted coils, where the hole is surrounded by the ring. Some embodiments include a sheath that is attached to a radial surface of the interrupted coils, where the hole passes radially though the sheath.

MULTIPLE-FIRING SUTURE FIXATION DEVICE AND METHODS FOR USING AND MANUFACTURING SAME

A multiple-firing clip device includes a hollow shaft defining a lateral opening communicating with an environment and a distal shaft portion between the lateral opening and a distal end opening. A shuttle longitudinally moves on the shaft and comprises a shuttle body defining a lumen surrounding the shaft, a snare, and a snare-extender slide defining a snare track to form a snare travel path in which the snare is disposed from the body and through the track and a portion of the body. The slide moves along a given extent defining a slide distance and a distal end and movement of the slide to the distal end shortens the snare travel path to extend the snare portion through the lateral opening, through the distal shaft portion, and distally out from a distal side of the body longer than the given extent to secure a suture with the snare. 1. A multiple-firing clip device , comprising:a hollow shaft having a distal clip fixation location, an exterior surface, a distal shaft end, and an interior, the shaft defining a lateral opening proximal to the distal clip fixation location, the lateral opening communicating between the interior and an environment outside the exterior surface;a plurality of suture fixation clips each having an internal hollow shaped to receive therein at least one suture, the plurality of the suture fixation clips stacked in the interior, defining a first clip, and configured to move along a longitudinal axis;a clip movement assembly within the interior of the shaft and configured to deliver the first clip to the distal clip fixation location by moving the first clip longitudinally from a first proximal position into the distal clip fixation location; and a snare-movement body comprising a hollow, snare-guiding tube having a distal tube end;', 'a snare operatively connected to the snare-movement body and having a distal snare portion; and', 'an interior body defining a portion of a snare guide path aligned with the snare-guiding tube to form a snare ...

SUTURE CLIPS, DEPLOYMENT DEVICES THEREFOR, AND METHODS OF USE

A device for deploying a suture clip onto a suture can include a proximal handle portion that includes an actuation mechanism. The device can also include an outer shaft defining an inner lumen. A crimping assembly can be at least partially disposed within a distal end of the outer shaft. The crimping assembly can include a plurality of crimping members configured to receive and radially compress a suture clip. The actuating mechanism can be configured to move the plurality of crimping members radially inwardly from a first position, where the crimping members are configured to receive a suture clip, to a second position where the plurality of crimping members are configured to radially compress the suture clip, causing the suture clip to plastically deform and become secured around one or more sutures. 1. A device for deploying a suture clip onto a suture , comprising:a proximal handle portion comprising an actuation mechanism;an outer shaft defining an inner lumen; anda crimping assembly disposed at least partially within a distal end of the outer shaft, the crimping assembly comprising a plurality of crimping members configured to receive and radially compress a suture clip;wherein the actuation mechanism is configured to move the plurality of crimping members radially inwardly from a first position where the crimping members are configured to receive the suture clip to a second position where the plurality of crimping members are configured to radially compress the suture clip, causing the suture clip to plastically deform.2. The device of claim 1 , further comprising an inner shaft disposed at least partially within the inner lumen of claim 1 , and axially moveable relative to claim 1 , the outer shaft.3. The device of claim 2 , wherein the actuation mechanism is configured to move the inner shaft axially claim 2 , proximally or distally claim 2 , relative to the outer shaft.4. The device of claim 1 , wherein the plurality of crimping members are articulated.5. ...

Suturing devices for heart valve surgery

Disclosed are devices and methods for delivering several sutures accurately and simultaneously around the perimeter of an annular prosthetic device (prosthetic heart valve, annuloplasty ring, etc.) to secure the prosthetic device within a native heart valve region. Devices can comprise a proximal handle portion including an actuator and a distal suturing portion including several curved and straight needles arrayed around the shaft axis. The straight needles and the curved needles are configured to simultaneously guide a plurality of sutures through the native tissue and through the annular prosthetic device. The actuator can cause the straight needles to move axially relative to the curved needles and can also cause the curved needles to rotate, such that the motions are coordinated to simultaneously place all the sutures.

DELIVERY SYSTEMS FOR PROSTHETIC HEART VALVE

Described herein are systems and methods from delivering prosthetic devices, such as prosthetic heart valves, through the body and into the heart for implantation therein. The prosthetic devices delivered with the delivery systems disclosed herein are, for example, radially expandable from a radially compressed state mounted on the delivery system to a radially expanded state for implantation using an inflatable balloon of the delivery system. Exemplary delivery routes through the body and into the heart include transfemoral routes, transapical routes, and transaortic routes, among others. 1. A delivery device for implantation of a prosthetic heart valve within a heart , the prosthetic heart valve being radially expandable from a radially compressed state to a radially expanded state , the delivery device comprising:a catheter;an inflatable balloon position at a distal portion of the catheter; anda proximal stop and a distal stop coupled to the catheter and configured to limit longitudinal movement of the prosthetic heart valve relative to the balloon while the prosthetic heart valve is mounted over the balloon in the radially compressed state between the proximal stop and the distal stop;wherein the proximal stop and the distal stop are at least partially positioned within the balloon and configured to be positioned adjacent a respective end of the prosthetic heart valve when the prosthetic heart valve is radially compressed between the proximal and distal stops; andwherein the proximal and distal stops each comprise at least one passageway that allows balloon inflation fluid to flow radially inwardly or radially outwardly through the proximal and distal stops.2. The delivery device of claim 1 , wherein the passageways of the proximal and distal stops allow the proximal and distal stops to be radially compressed to a smaller diameter.3. The delivery device of claim 1 , wherein the at least one passageway comprises at least one longitudinally extending slot in each ...

Suture clip deployment devices

Disclosed herein are suture clip delivery devices that can be loaded with several flat, disk-shaped suture clips and can deploy the suture clips one after another onto respective sutures without reloading the device with additional suture clips. An exemplary device includes a handle portion with an actuation mechanism that is coupled to a shaft portion that holds and deploys the suture clips. The shaft portion includes a mandrel on which the suture clips are mounted and a retainer that restricts the suture clips from moving proximally when the actuation mechanism pulls the mandrel proximally, which causes a distal-most suture clip to slide off the mandrel and be deployed onto one or more suture. The mandrel and remaining suture clips can them move distally to prepare to deploy the next suture clip.

SUTURE CLIPS, DEPLOYMENT DEVICES THEREFOR, AND METHODS OF USE

A device for deploying a suture clip onto a suture can include a proximal handle portion that includes an actuation mechanism. The device can also include an outer shaft defining an inner lumen. A crimping assembly can be at least partially disposed within a distal end of the outer shaft. The crimping assembly can include a plurality of crimping members configured to receive and radially compress a suture clip. The actuating mechanism can be configured to move the plurality of crimping members radially inwardly from a first position, where the crimping members are configured to receive a suture clip, to a second position where the plurality of crimping members are configured to radially compress the suture clip, causing the suture clip to plastically deform and become secured around one or more sutures. 1. A device for deploying a suture clip onto a suture , comprising:a proximal handle portion comprising an actuator;an outer shaft defining an inner lumen;an inner shaft at least partially disposed within the inner lumen of the outer shaft and axially moveable relative to the outer shaft; anda crimping assembly disposed at least partially within a distal end of the outer shaft, the crimping assembly comprising a plurality of opposed crimping members pivotably coupled to the inner shaft and configured to receive and radially compress a suture clip, wherein a given crimping member of the plurality of opposed crimping members defines a distal jaw portion, distal jaw portions of the plurality of opposed crimping members configured to receive and radially compress the suture clip and being at least partially disposed within the inner lumen of the distal end of the outer shaft;wherein the actuator is configured to axially move the inner shaft relative to the outer shaft such that the plurality of opposed crimping members move radially inwardly from a first position where the plurality of opposed crimping members are configured to receive the suture clip to a second ...

Suture clip deployment devices

Disclosed herein are suture clip delivery devices that can be loaded with several flat, disk-shaped suture clips and can deploy the suture clips one after another onto respective sutures without reloading the device with additional suture clips. An exemplary device includes a handle portion with an actuation mechanism that is coupled to a shaft portion that holds and deploys the suture clips. The shaft portion includes a mandrel on which the suture clips are mounted and a retainer that restricts the suture clips from moving proximally when the actuation mechanism pulls the mandrel proximally, which causes a distal-most suture clip to slide off the mandrel and be deployed onto one or more suture. The mandrel and remaining suture clips can them move distally to prepare to deploy the next suture clip.

Suture clip deployment device

Disclosed herein are suture clip delivery devices that can be loaded with several flat, disk-shaped suture clips and can deploy the suture clips one after another onto respective sutures without reloading the device with additional suture clips. An exemplary device includes a handle portion with an actuation mechanism that is coupled to a shaft portion that holds and deploys the suture clips. The shaft portion includes a mandrel on which the suture clips are mounted and a retainer that restricts the suture clips from moving proximally when the actuation mechanism pulls the mandrel proximally, which causes a distal-most suture clip to slide off the mandrel and be deployed onto one or more suture. The mandrel and remaining suture clips can them move distally to prepare to deploy the next suture clip.

Spring cannulae

Disclosed herein are embodiments of spring cannulae, including one or more holes in the sidewall of the cannula. Some disclosed cannulae include a wire, helically wound to form coils, and at least one hole in the cannula that interrupts one or more of the coils. Some embodiments further include a fused region of the coils through which the hole passes. Some embodiments include a ring attached to ends of the interrupted coils, where the hole is surrounded by the ring. Some embodiments include a sheath that is attached to a radial surface of the interrupted coils, where the hole passes radially though the sheath.

Suturing devices for heart valve surgery

Disclosed are devices and methods for delivering several sutures accurately and simultaneously around the perimeter of an annular prosthetic device (prosthetic heart valve, annuloplasty ring, etc.) to secure the prosthetic device within a native heart valve region. Devices can comprise a proximal handle portion including an actuator and a distal suturing portion including several curved and straight needles arrayed around the shaft axis. The straight needles and the curved needles are configured to simultaneously guide a plurality of sutures through the native tissue and through the annular prosthetic device. The actuator can cause the straight needles to move axially relative to the curved needles and can also cause the curved needles to rotate, such that the motions are coordinated to simultaneously place all the sutures.

DELIVERY SYSTEMS FOR PROSTHETIC HEART VALVE

Described herein are systems and methods from delivering prosthetic devices, such as prosthetic heart valves, through the body and into the heart for implantation therein. The prosthetic devices delivered with the delivery systems disclosed herein are, for example, radially expandable from a radially compressed state mounted on the delivery system to a radially expanded state for implantation using an inflatable balloon of the delivery system. Exemplary delivery routes through the body and into the heart include transfemoral routes, transapical routes, and transaortic routes, among others. 1. A delivery device for implantation of a prosthetic heart valve within a heart , the prosthetic heart valve being radially expandable from a radially compressed state to a radially expanded state , the delivery device comprising:a catheter;an inflatable balloon positioned adjacent a distal portion of the catheter;an inner shaft positioned within the balloon;a mounting member positioned around the inner shaft and within the balloon; anda distal stop at least partially positioned within the balloon and at least partially positioned around both the inner shaft and the mounting member, the distal stop configured to be positioned adjacent a distal end of the prosthetic heart valve when the prosthetic heart valve is mounted over the balloon and the mounting member in a radially compressed state;wherein there is a fluid pathway between an outer surface of the inner shaft and an inner surface of the mounting member that allows balloon inflation fluid to flow longitudinally through the prosthetic heart valve when the prosthetic heart valve is mounted over the balloon and the mounting member in the radially compressed state.2. The delivery device of claim 1 , wherein the mounting member comprises at least one opening proximal to the distal stop that allows balloon inflation fluid to flow radially through the mounting member.3. The delivery device of claim 2 , wherein the at least one ...

DELIVERY SYSTEMS FOR PROSTHETIC HEART VALVE

Described herein are systems and methods from delivering prosthetic devices, such as prosthetic heart valves, through the body and into the heart for implantation therein. The prosthetic devices delivered with the delivery systems disclosed herein are, for example, radially expandable from a radially compressed state mounted on the delivery system to a radially expanded state for implantation using an inflatable balloon of the delivery system. Exemplary delivery routes through the body and into the heart include transfemoral routes, transapical routes, and transaortic routes, among others. 1. A delivery device for implantation of a prosthetic heart valve within a heart , the prosthetic heart valve being radially expandable from a radially compressed state to a radially expanded state , the delivery device comprising:a catheter;an inflatable balloon positioned at a distal portion of the catheter; anda proximal stop and a distal stop at least partially positioned within the balloon and configured to be positioned adjacent respective ends of the prosthetic heart valve when the prosthetic heart valve is mounted over the balloon in a radially compressed state between the proximal and distal stops, such that the proximal and distal stops limit longitudinal movement of the prosthetic heart valve relative to the balloon; andwherein the proximal and distal stops each comprise at least one passageway that allows balloon inflation fluid to flow through the proximal and distal stops.2. The delivery device of claim 1 , wherein the at least one passageway comprises at least one longitudinally extending slot.3. The delivery device of claim 1 , wherein the at least one passageway allows the proximal and distal stops to be radially compressed to a smaller diameter.4. The delivery device of claim 1 , wherein at least one of the proximal and distal stops comprises at least three longitudinal slots that allow the stop to be radially compressed to a smaller diameter when the prosthetic ...

Controlled suture tensioning

A tensioning device (200) includes an elongate plunger (220), a plunger track housing (210) configured to receive the plunger therein at least in part, an elongate tube (205) configured to be coupled to the plunger track housing, and an actuator (230) configured to cause axial translation of at least a portion of the plunger within the plunger track housing.

Catheter clamping device

A clamping device (400) for a shaft of a catheter includes a first member (402) rotatably coupled to a second member (401). The first member (402) has an annular element (426) defining a central lumen (408), the outer surface of the annular element (426) having a non-circular cross-sectional profile, and the second member (401) defines a bore into which the annular element (426) extends, the bore having a non-circular cross-sectional profile. The device (400) can move between a release state wherein the central lumen (408) has a first diameter, and a clamped state wherein the central lumen (408) has a second diameter less than the first diameter.

Suture clips, deployment devices therefor, and methods of use

A device for deploying a suture clip onto a suture can include a proximal handle portion that includes an actuation mechanism. The device can also include an outer shaft defining an inner lumen. A crimping assembly can be at least partially disposed within a distal end of the outer shaft. The crimping assembly can include a plurality of crimping members configured to receive and radially compress a suture clip. The actuating mechanism can be configured to move the plurality of crimping members radially inwardly from a first position, where the crimping members are configured to receive a suture clip, to a second position where the plurality of crimping members are configured to radially compress the suture clip, causing the suture clip to plastically deform and become secured around one or more sutures.

Catheter clamping device

A clamping device (400) for a shaft of a catheter includes a first member (402) rotatably coupled to a second member (401). The first member (402) has an annular element (426) defining a central lumen (408), the outer surface of the annular element (426) having a non-circular cross-sectional profile, and the second member (401) defines a bore into which the annular element (426) extends, the bore having a non-circular cross-sectional profile. The device (400) can move between a release state wherein the central lumen (408) has a first diameter, and a clamped state wherein the central lumen (408) has a second diameter less than the first diameter.

Suture clips, deployment devices therefor, and methods of use

Catheter clamping device

A clamping device for a shaft of a catheter can include a first member rotatably coupled to a second member. The first member can have an annular element defining a central lumen, the outer surface of the annular element having a non-circular cross-sectional profile, and the second member can define a bore into which the annular element extends, the bore having a non-circular cross-sectional profile. The device can move between a release state wherein the central lumen has a first diameter, and a clamped state wherein the central lumen has a second diameter less than the first diameter. When the clamping device is in the clamped state, the clamping device can engage an outer surface of a catheter shaft and when the clamping device is in the release state, the clamping device can be moved along a length of the catheter shaft.

Catheter clamping device

A clamping device for a catheter shaft can include a first member having a first indicator surface and defining a first inner bore having a non-circular cross-sectional profile, and a second member having a second indicator surface, and an extending annular element defining a second inner bore, the annular element received within the first inner bore and comprising an outer surface having a non-circular cross-sectional profile. The clamping device can be movable between a release state in which the second inner bore has a first diameter, and a clamped state in which the second inner bore has a second diameter less than the first diameter.

Delivery systems for prosthetic heart valve

Described herein are systems and methods from delivering prosthetic devices, such as prosthetic heart valves, through the body and into the heart for implantation therein. The prosthetic devices delivered with the delivery systems disclosed herein are, for example, radially expandable from a radially compressed state mounted on the delivery system to a radially expanded state for implantation using an inflatable balloon of the delivery system. Exemplary delivery routes through the body and into the heart include transfemoral routes, transapical routes, and transaortic routes, among others.

Suturing devices for heart valve surgery

Disclosed are devices and methods for delivering several sutures accurately and simultaneously around the perimeter of an annular prosthetic device (prosthetic heart valve, annuloplasty ring, etc.) to secure the prosthetic device within a native heart valve region. Devices can comprise a proximal handle portion including an actuator and a distal suturing portion including several curved and straight needles arrayed around the shaft axis. The straight needles and the curved needles are configured to simultaneously guide a plurality of sutures through the native tissue and through the annular prosthetic device. The actuator can cause the straight needles to move axially relative to the curved needles and can also cause the curved needles to rotate, such that the motions are coordinated to simultaneously place all the sutures.

Suturing devices for heart valve surgery

Disclosed are devices and methods for delivering several sutures accurately and simultaneously around the perimeter of an annular prosthetic device (prosthetic heart valve, annuloplasty ring, etc. ) to secure the prosthetic device within a native heart valve region. Devices can comprise a proximal handle portion including an actuator and a distal suturing portion including several curved and straight needles arrayed around the shaft axis. The straight needles and the curved needles are configured to simultaneously guide a plurality of sutures through the native tissue and through the annular prosthetic device. The actuator can cause the straight needles to move axially relative to the curved needles and can also cause the curved needles to rotate, such that the motions are coordinated to simultaneously place all the sutures.

Suturing devices for heart valve surgery

Disclosed are devices and methods for delivering several sutures accurately and simultaneously around the perimeter of an annular prosthetic device (prosthetic heart valve, annuloplasty ring, etc. ) to secure the prosthetic device within a native heart valve region. Devices can comprise a proximal handle portion including an actuator and a distal suturing portion including several curved and straight needles arrayed around the shaft axis. The straight needles and the curved needles are configured to simultaneously guide a plurality of sutures through the native tissue and through the annular prosthetic device. The actuator can cause the straight needles to move axially relative to the curved needles and can also cause the curved needles to rotate, such that the motions are coordinated to simultaneously place all the sutures.

Suturing devices for heart valve surgery

Disclosed are devices and methods for delivering several sutures accurately and simultaneously around the perimeter of an annular prosthetic device (prosthetic heart valve, annuloplasty ring, etc.) to secure the prosthetic device within a native heart valve region. Devices can comprise a proximal handle portion including an actuator and a distal suturing portion including several curved and straight needles arrayed around the shaft axis. The straight needles and the curved needles are configured to simultaneously guide a plurality of sutures through the native tissue and through the annular prosthetic device. The actuator can cause the straight needles to move axially relative to the curved needles and can also cause the curved needles to rotate, such that the motions are coordinated to simultaneously place all the sutures.

Suturing devices for heart valve surgery

Disclosed are devices and methods for delivering several sutures accurately and simultaneously around the perimeter of an annular prosthetic device (prosthetic heart valve, annuloplasty ring, etc.) to secure the prosthetic device within a native heart valve region. Devices can comprise a proximal handle portion including an actuator and a distal suturing portion including several curved and straight needles arrayed around the shaft axis. The straight needles and the curved needles are configured to simultaneously guide a plurality of sutures through the native tissue and through the annular prosthetic device. The actuator can cause the straight needles to move axially relative to the curved needles and can also cause the curved needles to rotate, such that the motions are coordinated to simultaneously place all the sutures.

Spring cannulae

Disclosed herein are embodiments of spring cannulae, including one or more holes in the sidewall of the cannula. Some disclosed cannulae include a wire, helically wound to form coils, and at least one hole in the cannula that interrupts one or more of the coils. Some embodiments further include a fused region of the coils through which the hole passes. Some embodiments include a ring attached to ends of the interrupted coils, where the hole is surrounded by the ring. Some embodiments include a sheath that is attached to a radial surface of the interrupted coils, where the hole passes radially though the sheath.

Delivery systems for prosthetic heart valve

Described herein are systems and methods from delivering prosthetic devices, such as prosthetic heart valves, through the body and into the heart for implantation therein. The prosthetic devices delivered with the delivery systems disclosed herein are, for example, radially expandable from a radially compressed state mounted on the delivery system to a radially expanded state for implantation using an inflatable balloon of the delivery system. Exemplary delivery routes through the body and into the heart include transfemoral routes, transapical routes, and transaortic routes, among others.

Catheter clamping device

A clamping device for a catheter shaft can include a first member having a first indicator surface and defining a first inner bore having a non-circular cross-sectional profile, and a second member having a second indicator surface, and an extending annular element defining a second inner bore, the annular element received within the first inner bore and comprising an outer surface having a non-circular cross-sectional profile. The clamping device can be movable between a release state in which the second inner bore has a first diameter, and a clamped state in which the second inner bore has a second diameter less than the first diameter.

Trigger-based tissue anchor deployment

A medical instrument includes a handle, a suture lock associated with the handle, the suture lock being configured to fix a position of a portion of a suture line relative to a portion of the handle when the suture lock is in a locked configuration, and a manually-actuatable actuator associated with the handle and configured to cause the suture lock to transition from the locked position to an unlocked position.

Suture clips and deployment devices therefor

Suture clip deployment device

Disclosed herein are suture clip delivery devices that can be loaded with several flat, disk-shaped suture clips and can deploy the suture clips one after another onto respective sutures without reloading the device with additional suture clips. An exemplary device includes a handle portion with an actuation mechanism that is coupled to a shaft portion that holds and deploys the suture clips. The shaft portion includes a mandrel on which the suture clips are mounted and a retainer that restricts the suture clips from moving proximally when the actuation mechanism pulls the mandrel proximally, which causes a distal-most suture clip to slide off the mandrel and be deployed onto one or more suture. The mandrel and remaining suture clips can them move distally to prepare to deploy the next suture clip.

Suture clip deployment device

Disclosed herein are suture clip delivery devices that can be loaded with several flat, disk-shaped suture clips and can deploy the suture clips one after another onto respective sutures without reloading the device with additional suture clips. An exemplary device includes a handle portion with an actuation mechanism that is coupled to a shaft portion that holds and deploys the suture clips. The shaft portion includes a mandrel on which the suture clips are mounted and a retainer that restricts the suture clips from moving proximally when the actuation mechanism pulls the mandrel proximally, which causes a distal-most suture clip to slide off the mandrel and be deployed onto one or more suture. The mandrel and remaining suture clips can them move distally to prepare to deploy the next suture clip.