Dolomite wet process comprehensive utilization technique

The invention discloses a process of wet comprehensive utilization of dolomite, more specifically relates to a process for wet treatment of the dolomite to produce calcium and magnesium products, namely, the dolomite or incinerated dolomite powder is directly leached with sulfate acid to separate the calcium and the magnesium in the dolomite. The calcium precipitates in the form of calcium sulfate and the magnesium enters a solution in the form of magnesium sulfate; then magnesium hydroxide and calcium sulfate products are prepared from the magnesium solution after metathetical reaction and neutralization reaction. The intermediate product, calcium chloride, of the invention can be recycled, so the process is basically free of three-waste discharge and has notable environmental benefit; the invention, besides, significantly lowers the resource consumption and has obvious economic benefit.

Preparation technology for piperonal crystal

The invention belongs to the technical field of chemical crystallization, and particularly relates to a preparation technology for piperonal crystal. The preparation technology comprises the following specific processes: mixing a piperonal crude product with absolute ethyl alcohol in a ratio, and putting the mixture into a crystallizer; adding an appropriate crystal modifier, and heating for completely dissolving solid substances; carrying out temperature-control cooling crystallizing; adding piperonal seed crystal before inoculating the crystal, and cooling to a final temperature; and growing the grain, filtering, washing and drying to obtain a piperonal crystal product. According to the preparation technology provided by the invention, the wall sticking problem in a high-concentration crystallization process can be effectively avoided; the granularity of the prepared piperonal crystal product is greater than 1mm; the granularity distribution is uniform; the product is high in purity and ...

Preparation method of styliform nano calcium carbonate

The invention relates to a preparation method of an acicular nanometer calcium carbonate which does not use a refrigerator, mixes a certain quantity of quick lime with hot water in the proportion of 1:4-10 under the condition of higher temperature and higher concentration of the lime white which are filtered and removed the residue. Before carbonizing, the solution is adjusted to the needed concentration and the temperature, then is added with the crystal-directing agents, then is evenly stirred and then is placed into a carbonation reactor, reacting with the mixed air pumped containing CO2 15-40 percent is pumped. The reaction is stopped when the pH equals to 6.5-7. The reaction solution is prepared to obtain acicular nanometer calcium carbonate by dewatering, cleaning, drying, surface processing, grinding and sieving. The invention has the advantages of realizing an industrial production by adopting the industry bubbling shaped carbonization device as well as utilizing the crystal-directing ...

Method for preparing magnesium hydroxide with coproduction of calcium chloride

The invention relates to a method for preparing magnesium hydroxide with joint production of calcium chloride which is that magnesium chloride and lime milk are adopted as the raw material; solubility difference between reactant and product in the water are utilized; the process flow is reasonably arranged; double decomposition reaction is completed with the method of removing calcium agent; the content of calcium oxide in product magnesium hydroxide is less than 0.5 percent; utilization ratio of the magnesium reaches more than 95 percent. Compared with the magnesium hydroxide method, the invention has low production cost with calcium chloride as byproduct and also has high conversion rate of the magnesium compared with ammonia method, with no discharging of nitrogen wastewater with the ammonia and no air pollution. The invention realizes the zero discharge of the water by regularly recycling lavage fluid and the water with remarkable environmental and economic benefits.

Saponin class antifungal compounds Variegatuside F to I in stichopus variegatus

The invention relates to the technical field of the medicine and four novel saponin class antifungal compounds Variegatuside F, G, H and I separated and obtained from marine animal stichopus variegatus. The chemical structure general formula is shown in the right formula (I), wherein R1, R2, R3 and R4 group collocations of each compound are respectively shown in the right formula (II). An experiment indicates that the invention has obvious fungus-suppressing activity, thus the invention can be used for preparing antifungal medicine. The invention provides a novel leading compound for developing novel antifungal medicine.

Open loop steroid saponin compound with antibacterial activity in sinularia gyrosa

The invention relates to two open loop steroid saponin compounds, i.e. Sinularoside A and Sinularoside B with antibacterial activity, separated from sinularia gyrosa, belonging to the technical field of medicines. The compounds have the chemical structural formulas as the specification, wherein the R group is FORMULA. The in-vitro antibacterial test on the Sinularoside A and the Sinularoside B shows that the compounds have obvious effect for inhibiting fungus, bacteria and algae for test, thereby the two open loop steroid saponin compounds can be used for preparing antibacterial medicaments. The invention provides a new lead compound for developing new antibacterial medicaments and has great significance for developing ocean medicine biological resources in China.

Single-chip-microcomputer-control-based storage battery power supply device

Disclosed in the utility model is a single-chip-microcomputer-control-based storage battery power supply device, which belongs to the storage battery power supply device field. The storage battery power supply device comprises a single-chip microcomputer control module that are connected to at least two battery groups respectively by a first voltage acquisition circuit and a second voltage acquisition circuit. The single-chip microcomputer control module is also connected with an output circuit connected to at least two battery groups. Besides, the single-chip microcomputer control module is also connected with an arc voltage acquisition circuit and a charging circuit; the charging circuit is respectively connected with at least two battery groups and a welding arc terminal. On the basis of the way of power supply by the storage battery, the peripheral unit of automatic dolly welding can be simplified; a special power line is not needed; and the application range of the welding dolly is ...

Airplane approach landing monitoring system

The invention provides an airplane approach landing monitoring system. The airplane approach landing monitoring system comprises an infrared sensor, a ground server, and display equipment. Compared with the prior art, according to the system, a standard landing route is constructed based on ingenious utilization of fixed and invariant glide track during approach landing of an airplane, the accurate approach landing monitoring system is constructed through the superposition of real-time images obtained through the infrared sensor during the landing process of the airplane, the real-time condition of a landing gear of the airplane can be monitored in the whole course, and the system is advantaged by more vivid observation images, convenient installation and implementation, simple structure, and low cost.

Saponins antineoplastic compound in Bohadschia argus Jaeger

Technology for producing active magnesium oxide

The invention relates to a technology for producing active magnesium oxide, comprising the following steps: adding a pre-pyrolysis device on the basis of the technology for producing active magnesium oxide by the traditional carbonization process; introducing dry tail gas obtained by drying light magnesium carbonate to the pre-pyrolysis device, carrying out direct heat exchange with heavy magnesium water, recovering heat in the tail gas, raising temperature of the heavy magnesium water from 10-30 DEG C to 40-55 DEG C and conveying heated heavy magnesium water to the pre-pyrolysis device for complete pyrolysis.In the invention, heat in the dry tail gas is recovered, temperature of heavy magnesium water is raised, primary energy consumption of unit product is lowered, magnesium carbonate dust carried in the dry tail gas is recovered, so that environmental pollution is reduced and multiple purposes are achieved.In addition, the economic and environmental benefits of the technology are remarkable ...

Storage battery power supply device controlled by single-chip microcomputer

The invention discloses a storage battery power supply device controlled by a single-chip microcomputer and belongs to the storage battery power supply device. The storage battery power supply device comprises a single-chip microcomputer control module which is connected with at least two battery packs through a first voltage collection circuit and a second voltage collection circuit; the single-chip microcomputer control module is also connected with an output circuit which is connected with the battery packs; the single-chip microcomputer control module is further connected with an arc voltage collection circuit and a charging circuit; the charging circuit is connected with the battery packs and a welding electric arc end. The peripherals of an automatic welding tractor are simplified in the storage battery power supply mode, a special power line is not needed, and the applicable range of the welding tractor is effectively widened; the arc voltage charging mode and the mode of self-charging ...

Preparation process of D-phenylglycine methyl ester hydrochloride crystals

The invention belongs to the technical field of the chemical industry, and in particular relates to a preparation process of D-phenylglycine methyl ester hydrochloride crystals. The preparation process comprises the following steps: sequentially adding methanol and D-phenylglycine into a reactor, stirring uniformly, and slowly adding sulfoxide chloride; controlling the temperature in the reactor below 55DEG C, and controlling the temperature in the reactor to be 55-65DEG C after adding sulfoxide chloride; performing reflux reaction, then performing vacuum azeotropic distillation, and finally performing temperature controlled cooling crystallization; and filtering, washing and drying to obtain a D-phenylglycine methyl ester hydrochloride crystal product. The preparation process provided by the invention is high in one-pass yield, the prepared product is high in purity, good in color grade and stable in quality, the preparation process is low in production cost, and the operation is easy ...

Saponins antineoplastic compound in Bohadschia argus Jaeger

The invention relates to medical technique, which in detail relates to a saponin antineoplastic compound Arguside B or Arguside C. The R1 in structure general formula represents OH or H, R2 represents CH3 or CH2OH, when R1 is OH and R2 is CH3, the compound is Arguside B; when R1 is H and R2 is CH2OH, the compound is Arguside C. The chemical structure and spatial configuration of said two compounds are determined through various modern spectral analysises, especially through analysis with multiple advanced nuclear magnetic resonance spectroscopy. It is tested that said two compounds are apparently inhibitive to seven cancers such as A- 549 lung cancer and MCF- 7 breast cancer. It can be used to prepare antineoplastic medicine. The invention provides leading compound for new antineoplastic medicine development, and is valuable for ocean biological resource utilization in China.

Triterpene glycosides antifungal compounds of sea cucumber HolotoxinD-I and preparation method thereof

The invention relates to the technical field of medicines, particularly to six triterpene glycosides antifungal compounds HolotoxinD-I separated from a sea cucumber. The chemical structural formula is as follow. An in vitro anifungal experiment shows that the compounds have obvious inhibitory effect on Candida ablbicans SC5314, Cryptococcus neoformans BLS108, Candida tropicalis, Trichophyton rubrum, Mircrosporum gypeseum and fuming Aspergillus. The invention can provide leading compounds for developing novel antifungal drug, and has a significant value on exploiting and using marine medical resources in China.

Automatic switch-on and switch-off device of overhead line of electric locomotive

The invention relates to an automatic switch-on and switch-off device of an overhead line of an electric locomotive, by which the electric locomotive is automatically switched on when a pantograph touches a power supply overhead line and is automatically switched off when the pantograph leaves the power supply overhead line. The automatic switch-on and switch-off device comprises a voltage detection unit, a current detection unit, an overcurrent detection unit, a main switch, a control unit, a display alarm unit and a control power supply unit, wherein the current detection unit, the overcurrent detection unit and the main switch are connected in series in a direct current major loop; the voltage detection unit is connected between the direct current major loop and the ground; the output ends of an overvoltage detection unit, the current detection unit and the overcurrent detection unit are all connected with the input end of the control unit for program control; the output end of thecontrol ...

Method of producing magnesium hydroxide

The invention discloses a preparation method of magnesium hydroxide by using magnesium sulfate and lime milk as raw materials, and the invention has the concrete process that a magnesium sulfate solution with a certain concentration can be used to conduct the metathesis reaction with a calcium chloride solution to produce the magnesium chloride solution and calcium sulfate precipitation; the filter mass is washed and dried after the solid-liquid separation to generate calcium sulfate products; the filter liquid continues to counteract with lime milk with a certain concentration to produce thecalcium chloride solution and the magnesium hydroxide precipitation; and then the filter mass is washed, dried and crashed after the solid-liquid separation to generate magnesium hydroxide products; and then the filter liquid returns to the metathesis reaction for recycling. The invention with low producing cost remarkably improves environmental and economic benefits.

Reduced anthraquinone compound with antibacterial activity

Saponin class antifungal compounds Variegatuside F to I in stichopus variegatus

The invention relates to the technical field of the medicine and four novel saponin class antifungal compounds Variegatuside F, G, H and I separated and obtained from marine animal stichopus variegatus. The chemical structure general formula is shown in the right formula (I), wherein R1, R2, R3 and R4 group collocations of each compound are respectively shown in the right formula (II). An experiment indicates that the invention has obvious fungus-suppressing activity, thus the invention can be used for preparing antifungal medicine. The invention provides a novel leading compound for developing novel antifungal medicine.

Furanone compound Cytosporanone A having antibacterial activity

The invention relates to the technical field of medicine, in particular to furanone compound Cytosporanone A which is separated from plant endophytic fungi Cytospora sp. leavening, has antibacterial activity and has the systematic name of (R)-5-((S)-hydroxy (phenyl)-methyl) dihydrofuran-2 (3H)-one, and the furanone compound Cytosporanone A has the chemical structural formula as follows. The in vitro antibacterial experiment proves that the compound Cytosporanone A has obvious bacteriostatic effect for botrytis cinerea, septoria musiva leaf blight fungi and bacillus megaterium, thus being used for preparing antibacterial medicines. The invention provides a lead compound for developing new antibacterial medicines, and has important valve for developing endophytic fungi medical resources of China.

Phytolaccagenin derivative and preparation method and application thereof

The invention discloses a phytolaccagenin derivative and a preparation method and application thereof. The general formula of the derivative is shown in the specifications, wherein R is amino acid, polypeptide, piperazinyl, substituted piperazinyl or substituted amidogen. An active ester intermediate which is formed by phytolaccagenin under the action of a condensing agent reacts with amine or piperazine or N-substituted piperazine or protected amino acid of carboxyl or polypeptide, and the reaction product is separated and purified so as to obtain the phytolaccagenin derivative. The phytolaccagenin derivative, pharmaceutic salt and a medicinal composition of the phytolaccagenin derivative can be used for preparing an anti-inflammatory medicament.

Application of Esculentoside A in preparing drugs for controlling hepatic fibrosis or cirrhosis

The invention which belongs to the technical field of medicine relates to a new use of Esculentoside A in preparing drugs for controlling hepatic fibrosis or cirrhosis. Pharmacological experiments show that: Esculentoside A allows the generation of collagen in hepatic tissues to be substantially inhibited, the fibrosis degree to be reduced and the control effect on hepatic fibrosis and cirrhosis to be fine, so Esculentoside A can be used to prepare the drugs for controlling hepatic fibrosis or cirrhosis. The invention provides a new drug resource for controlling hepatic fibrosis or cirrhosis.

Saponin antimycotic compounds in holothuria scabra jaeger and preparation method thereof

The invention relates to medicine technical field, in particular to two saponin antimycotics compounds as scabraside A and scabraside B, which molecular formulas are represented as C54H85O26SNa and C54H85O27SNa, separated from sea cucumber. The chemical structure and spatial configuration of the compounds are assured by kinds of modern spectrographic analysis, particularly by kinds of advanced two-dimension nuclear magnetic resonance spectroscopy. The compounds can effectively restrain various bacterial strains as candida albicans and aspergillus fumigatus by external antimycotics test. The inventive compounds can be used to prepare antimycotics drug. The invention provides lead compound for preparing new antimycotics drug, with significant value for developing and utilizing sea medical biological resource.

Brushless motor welding oscillator based on single chip microcomputer control and control method thereof

The invention discloses a brushless motor welding oscillator based on the single chip microcomputer control and a control method thereof and belongs to welding oscillators. The oscillator comprises a single chip microcomputer and a motor drive circuit; the single chip microcomputer is connected to an oscillating speed determination circuit, an oscillating angle determination circuit and an oscillating staying time determination circuit; the motor drive circuit is connected to the single chip microcomputer; the single chip microcomputer is further connected to a positioning sensor which is used for acquiring the current operation speed and direction of a brushless motor; the single chip microcomputer controls the operation speed, direction and staying time of the brushless motor according to the determined oscillation speed, oscillation angle and oscillation staying time through the motor drive circuit. The rotor position signal of the brushless motor serves as the oscillation angle signal ...

Dead weight breaks away from style automatic weld dolly magnetism adsorption equipment

The utility model discloses a dead weight breaks away from style automatic weld dolly magnetism adsorption equipment, category automatic weld dolly supporting devices, the device all is equipped with the movable mounting parts including magnet subassembly and magnetic switch subassembly, the both ends of magnet subassembly, and the one end swing joint of movable mounting parts and promotion handle is passed through to the wherein one end of magnet subassembly, and the other end that promotes the handle also is equipped with the movable mounting parts, the magnet subassembly includes the two magnet, also is equipped with between the two magnet at a distance from the magnet, and the two magnet is installing in the lower part of yoke of opposite polarity. Through promoting handle and magnet subassembly swing joint, the promotion handle can will be prized from the welding base metal with the magnet subassembly that promotes handle swing joint through the principle of lever, and operate and ...

Method of producing magnesium hydroxide

Application of 1,2-O-stearyl glyceraldehyde in preparing antibacterial agents

The invention relates to the technical field of medicine, in particular to novel application of a compound 1,2-O-stearyl glyceraldehyde in preparing antibacterial agents. Proved by in vitro anti-bacteria tests, the 1,2-O-stearyl glyceraldehyde has obvious inhibiting effect on anthersmut, and the inhibiting effect of the 1,2-O-stearyl glyceraldehyde is even stronger than that of penicillin or streptomycin which is a positive control medicine, thus the 1,2-O-stearyl glyceraldehyde can be used for preparing the antibacterial agents. The invention provides a lead compound for developing novel antibacterial agents and has important significance for developing and utilizing Chinese ocean medicinal resources.

Refining method of cis-3-(2, 5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro [4.5] dec-3-ene-2-ketone

The invention relates to the technical field of pesticide synthesis, in particular to a refining method of cis-3-(2, 5-dimethylphenyl)-4-hydroxy-8-methoxyl-1-azaspiro [4.5] dec-3-ene-2-ketone, and belongs to the technical field of pesticide synthesis. The preparation method comprises the following steps: mixing a cis-3-(2, 5-dimethylphenyl)-4-hydroxy-8-methoxyl-1-azaspiro [4.5] dec-3-ene-2-one crude product with methanol according to a certain ratio, heating and dissolving, adjusting the pH value to 2-3, adding water at a controlled rate, stirring and growing crystals for a period of time, cooling at a controlled rate, stirring and growing crystals for a period of time, filtering, and drying to obtain the cis-3-(2, 5-dimethylphenyl)-4-hydroxy-8-methoxyl-1-azaspiro [4.5] dec-3-ene-2-one. Carrying out suction filtration and drying to obtain a refined product of cis-3-(2, 5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro [4.5] dec-3-ene-2-ketone, namely the cis-3-(2, 5-dimethylphenyl)-4-hydroxy ...

Cytospolides with anti-tumor and antibacterial activity

The invention relates to the technical field of medicines, in particular to 16 cytospolides A-P which are separated from a plant endophytic fungus cytospora sp. fermentation product and have anti-tumor and antibacterial activity. The in-vitro anti-tumor test proves that the cytospolides A-P have the effect of obviously inhibiting HCT116 (human colon cancer cells), A549 (human lung cancer cells), QGY-7703 (human liver cancer cells), A375 (human melanoma cells), and U937 (human leukemia cells) tumor cell strains; and the in-vitro antibacterial test proves that the cytospolides A-P have the effect of obviously inhibiting microbotryum violaceum, septoria tritici, Escherichia coli and bacillus megaterium. Therefore, the cytospolides A-P can be used for preparing anti-tumor or antibacterial medicines, are novel lead compounds for developing the anti-tumor and antibacterial medicines, and have great significance for developing and utilizing plant endophyte resources.

Brushless motor welding wig -wag based on single chip microcomputer control

The utility model discloses a brushless motor welding wig -wag based on single chip microcomputer control belongs to a welding wig -wag, including singlechip motor -drive circuit, the singlechip inserts swing speed given circuit, the preset circuit of swing angle, the preset circuit of swing dwell time respectively, and motor -drive circuit also inserts the singlechip, the singlechip also inserts position sensor for obtain current brushless motor's functioning speed and orientation by position sensor, pass through motor -drive circuit according to swing speed, the swing angle and swing dwell time set for, control brushless motor's functioning speed, orientation and dwell time by the singlechip. The rotor position sigual who uses brushless motor has not only simplified swing position sensor and has more improved swing angel position control precision as wig -wag swing angle signal, function in the accuracy of wig -wag under unbalanced load time can be realized to the swing control flow of ...

Reduction anthraquinone compound with antibacterial activity

The invention relates to the technical field of medicaments. Three reduction anthraquinone antifungal compounds, namely Coniothranthraquinone one to three, are separated from plant endophytic fungi and have the chemical structural formulas shown in the specification. An in vitro anti-bacteria test shows that: the Coniothranthraquinone one has a remarkable inhibiting effect on anther smut and bacillus megaterium; and the Coniothranthraquinone two and the Coniothranthraquinone three have a remarkable inhibiting effect on botrytis cinerea. The invention provides a new lead compound for developing antibacterial medicaments, and has very important significance on protecting endangered medical plants.

High purity magnesium hydrate preparation method

The invention relates to a method for preparing high-purity magnesium hydroxide. Magnesium chloride and lime milk are taken as raw materials, and the process flow is reasonably arranged according to the difference in solubility of reactants and products in water, thus metathetical reaction is fully carried out. Refining reaction is carried out under the action of an extra physical field to remove a little calcium hydroxide from the magnesium hydroxide and realize the high-efficiency separation of calcium and magnesium, thus the high-purity magnesium hydroxide product is obtained. The content of the magnesium hydroxide in the product is more than 98.5%, the content of calcium oxide is less than 0.2%, and the utilization rate of the magnesium is up to 95%. Compared with sodium hydroxide method, the method has lower cost; compared with ammonia process, the method has higher magnesium conversion rate, no ammoniacal nitrogen wastewater discharge and no air pollution; compared with conventional ...

Application of 1,2-O-stearyl glyceraldehyde in preparing antibacterial agents

The invention relates to the technical field of medicine, in particular to novel application of a compound 1,2-O-stearyl glyceraldehyde in preparing antibacterial agents. Proved by in vitro anti-bacteria tests, the 1,2-O-stearyl glyceraldehyde has obvious inhibiting effect on anthersmut, and the inhibiting effect of the 1,2-O-stearyl glyceraldehyde is even stronger than that of penicillin or streptomycin which is a positive control medicine, thus the 1,2-O-stearyl glyceraldehyde can be used for preparing the antibacterial agents. The invention provides a lead compound for developing novel antibacterial agents and has important significance for developing and utilizing Chinese ocean medicinal resources.

Briarane type diterpenoid compounds with anti-tumor and antibacterial activities and application thereof

The invention relates to the technical field of medicines, discloses 53 novel Briarane type diterpenoid compounds with anti-tumor and antibacterial activities, i.e. gemmacolides G-Z and gemmacolides ZI-ZXXXIII, which are obtained through the separation of marine animal gorgonian Dichotella gemmacea, and also discloses two known compounds, i.e., Juncin O and Junceellolide C. Experiments of anti-tumor and antibacterial activities in vitro show that the compounds disclosed by the invention have obvious inhibiting effects on multiple tumor cells such as A549 (human lung cancer cells), U251 ( human brain glioma cells) and MG63 (human bone sarcoma cells) and the like and has obvious bacteriostatic activity on anther smut fungus, septoria musiva septoria tritici, escherichia coli and enormous bacillus and the like; and therefore, the compounds can be used for preparing anti-tumor or antibacterial medicines. The invention has the advantages of providing a leading compound for the research of new ...

Automatic switch-on and switch-off device of overhead line of electric locomotive

The invention relates to an automatic switch-on and switch-off device of an overhead line of an electric locomotive, by which the electric locomotive is automatically switched on when a pantograph touches a power supply overhead line and is automatically switched off when the pantograph leaves the power supply overhead line. The automatic switch-on and switch-off device comprises a voltage detection unit, a current detection unit, an overcurrent detection unit, a main switch, a control unit, a display alarm unit and a control power supply unit, wherein the current detection unit, the overcurrent detection unit and the main switch are connected in series in a direct current major loop; the voltage detection unit is connected between the direct current major loop and the ground; the output ends of an overvoltage detection unit, the current detection unit and the overcurrent detection unit are all connected with the input end of the control unit for program control; the output end of the control ...

Diterpenoid compounds having anti-tumor activity and application of diterpenoid compounds

The invention relates to diterpenoid compounds having anti-tumor activity and application of the diterpenoid compounds. Nine novel Briarane-type diterpenoid compounds Gemmacolides AS-BA having anti-tumor activity are separated from a marine animal dichotella gemmacea and in-vitro anti-tumor activity experiments confirm that the nine compounds have inhibiting effects on five cancer cells, namely, A549 (human lung cancer cells), HCT116 (human colon cancer cells), QGY-7703 (human liver cancer cells), U937 (human leukemia cells) and MG63 (human osteosarcoma cells) and thus the diterpenoid compounds can be used for preparation of anti-tumor drugs. The diterpenoid compounds provide leading compounds for development of novel anticancer drugs and are conducive to the development and application of marine medicinal resources.

Process for removing calcium from magnesite

The invention relates to a process for removing calcium from magnesite. The process is characterized by finally reducing the content of calcium oxide below 1.5% through magnesite calcination, slaking, calcium removal, filtration, washing, drying and other treatment procedures. The process has the following beneficial effects: the magnesium hydroxide product which is obtained after removing calcium and has content of calcium oxide being lower than 1.5% can be directly applied to the fields such as flame retardants, oil additives, water treatment neutralizers and the like; other high value-added magnesium-containing materials such as industrial magnesium oxide, electrician magnesium oxide, fused magnesium oxide, light magnesium carbonate and the like can be further processed and produced; and compared with the existing processes for removing calcium from magnesite, the process has the advantages of short flow, low cost, flexible product scheme, thorough calcium removal and the like.

Application of perylenequinone compound Hypocrellin B or Hypocrellin C in preparation of antifungal medicines

The invention belongs to the technical field of medicines and relates to application of perylenequinone compound Hypocrellin B or Hypocrellin C in the preparation of antifungal medicines. The perylenequinone compound Hypocrellin B or the perylenequinone compound Hypocrellin C chemical structure is respectively shown as below. An in-vitro antifungal test indicates that the compound Hypocrellin B and the Hypocrellin C both have strong antifungal activity, thereby being used for preparing the antifungal medicines. The invention provides a lead compound for developing new antifungal medicines.

Preparation method of styliform nano calcium carbonate

The invention relates to a preparation method of an acicular nanometer calcium carbonate which does not use a refrigerator, mixes a certain quantity of quick lime with hot water in the proportion of 1:4-10 under the condition of higher temperature and higher concentration of the lime white which are filtered and removed the residue. Before carbonizing, the solution is adjusted to the needed concentration and the temperature, then is added with the crystal-directing agents, then is evenly stirred and then is placed into a carbonation reactor, reacting with the mixed air pumped containing CO2 15-40 percent is pumped. The reaction is stopped when the pH equals to 6.5-7. The reaction solution is prepared to obtain acicular nanometer calcium carbonate by dewatering, cleaning, drying, surface processing, grinding and sieving. The invention has the advantages of realizing an industrial production by adopting the industry bubbling shaped carbonization device as well as utilizing the crystal-directing ...

Furanone compound Cytosporanone A having antibacterial activity

The invention relates to the technical field of medicine, in particular to furanone compound Cytosporanone A which is separated from plant endophytic fungi Cytospora sp. leavening, has antibacterial activity and has the systematic name of (R)-5-((S)-hydroxy (phenyl)-methyl) dihydrofuran-2 (3H)-one, and the furanone compound Cytosporanone A has the chemical structural formula as follows. The in vitro antibacterial experiment proves that the compound Cytosporanone A has obvious bacteriostatic effect for botrytis cinerea, septoria musiva leaf blight fungi and bacillus megaterium, thus being used for preparing antibacterial medicines. The invention provides a lead compound for developing new antibacterial medicines, and has important valve for developing endophytic fungi medical resources of China.

Saponin antimycotic compounds in holothuria scabra jaeger and preparation method thereof

The invention relates to medicine technical field, in particular to two saponin antimycotics compounds as scabraside A and scabraside B, which molecular formulas are represented as C54H85O26SNa and C54H85O27SNa separated from sea cucumber. The chemical structure and spatial configuration of the compounds are assured by kinds of modern spectrographic analysis, particularly by kinds of advanced two-dimension nuclear magnetic resonance spectroscopy. The compounds can effectively restrain various bacterial strains as candida albicans and aspergillus fumigatus by external antimycotics test. The inventive compounds can be used to prepare antimycotics drug. The invention provides lead compound for preparing new antimycotics drug, with significant value for developing and utilizing sea medical biological resource.

Use of saponins compound echinoside A in sea pumpkin in preparing tumor topoisomerase ó� inhibitor

The invention relates to an application of a saponin compound echinoside A extracted from sea cucumber in preparing tumor topoismerase II inhibitors, belonging to the technical field of pharmaceuticals. The compound echinoside A has a molecular formula of C54H87O26SNa, and the chemical structure and the spatial configuration of the compound are determined through analysis of multiple modern spectra including advanced two-dimensional nuclear magnetic resonance spectra. In vitro tests indicate that the compound has distinct inhibitory effect on tumor topoismerase II (Topo II), and is an effective Topo II inhibitor. The invention provides a lead compound for developing Topo II inhibitors, and is important for developing and unitizing Chinese ocean medicinal biological resources.

二色桌片参中新的抗肿瘤化合物Intercedenside B

... 本发明涉及医药技术领域，具体为一种从二色桌片参中分离的抗癌化合物Intercedenside B，分子式C#-[55]H#-[84]O#-[28]S#-[2]Na#-[2]。经多种现代光谱分析，特别是应用多种先进的二维核磁共振谱的综合解析，确定了该化合物的化学结构及立体构型。体外抗肿瘤试验表明，该化合物对IA-9卵巢癌和A-549人肺癌等10种肿瘤细胞株有明显的抑制作用。本发明可为研制新的抗肿瘤药物提供先导化合物，对开发利用中国的海洋药用生物资源具有重要价值。 ...

Triterpene glycosides antifungal compounds of sea cucumber HolotoxinD-I and preparation method thereof

The invention relates to the technical field of medicines, particularly to six triterpene glycosides antifungal compounds HolotoxinD-I separated from a sea cucumber. The chemical structural formula isas follows on the right. An in vitro anifungal experiment shows that the compounds have obvious inhibitory effect on Candida ablbicans SC5314, Cryptococcus neoformans BLS108, Candida tropicalis, Trichophyton rubrum, Mircrosporum gypeseum and fuming Aspergillus. The invention can provide leading compounds for developing novel antifungal drug, and has a significant value on exploiting and using marine medical resources in China.

Novel anti-tumor compound Intercedenside B from picolour zhuopianshen

A kind of anticancer compound Intercedenside B whose molecular formula is C55H84O28S2Na2 separated from mensa maria intercedens is disclosed in the invention, which is belong to medicine technology field. After modern multi-spectrum and in particular many advanced 2D NMR synthesis analysis, chemistry structure and tridimensional structure of the compound are confirmed as a new compound. The antiknub test in vitro indicates that the compound has obvious restraint effect to IA-9 ovary cancer and A-549 human lung cancer etc. 10 kinds of human knub cell strain. The invention provides forerunner compound for new antiknub medicine preparation, and has important value for exploitation and usage of Chinese ocean biology resource as medicine.

Open loop steroid saponin compound with antibacterial activity in sinularia gyrosa

The invention relates to two open loop steroid saponin compounds, i.e. Sinularoside A and Sinularoside B with antibacterial activity, separated from sinularia gyrosa, belonging to the technical field of medicines. The compounds have the chemical structural formulas as the specification, wherein the R group is FORMULA. The in-vitro antibacterial test on the Sinularoside A and the Sinularoside B shows that the compounds have obvious effect for inhibiting fungus, bacteria and algae for test, thereby the two open loop steroid saponin compounds can be used for preparing antibacterial medicaments. The invention provides a new lead compound for developing new antibacterial medicaments and has great significance for developing ocean medicine biological resources in China.

Polyhydroxy steroid compounds and purpose thereof

The invention relates to the technical field of medicine. The invention provides a class of polyhydroxy steroid compounds which are separated from three corals (Muriceopsis flavida, Sarcophyton sp., and Anthogorgia sp.) collected from Hainan and have antibacterial and anti-microalgae activity, and the chemical structure formula of the polyhydroxy steroid compounds is as shown in the following picture. In vitro antibacterial tests show that the compounds, which contains Muristeroids A-G, Sarcsteroids A-F, Anthsteroids A-B, cholesteric-5alpha, 6beta-diol-3beta-acetic acid ester, cholesteric-5alpha-methoxy-3beta, 6beta-diol, (22E)-22-alkene-cholesteric-3beta, 5alpha, 6beta-triol, 24(28)-alkene-ergosta-3beta, 5alpha, 6beta-triol, cholesteric-3beta, 5alpha, 6beta-triol, cholesteric-1beta, 3beta, 5alpha and 6beta-tetrol, have an obvious effect of inhibiting fungi, bacteria and algae, and can be used for preparing antibacterial and anti-microalgae medicaments. The polyhydroxy steroid compounds ...

Application of esculentoside A in preparing medicament for preventing or treating pulmonary fibrosis

The invention relates to the technical field of medicine, in particular to Phytolacca acinsa, the time-honored traditional Chinese medicine. The main active component of Esculentoside is Esculentoside A, EsA), which is a favorable COX-II (cyclooxygenase-2) inhibitor having good effects on inhabiting inflammatory response. The invention aims to provide the novel application of EsA in the preparation of medicine for preventing or treating pulmonary fibrosis. According to pharmacological tests, the EsA of the invention can obviously resist forming the fibrosis of lung tissues, therefore, the invention is applicable in preventing and treating the related diseases and has a good prospect of medicine application.

Esculentoside A, EsA as well as preparation method and application thereof

The invention discloses an Esculentoside A, EsA as well as a preparation method and application thereof. The general formula of the Esculentoside A, EsA is shown in the specification, wherein R is amino acid, polypeptide, piperazine base, substituted piperazine bases or substituted amido. An active ester intermediate formed by the Esculentoside A, EsA under the action of a condensation agent reacts with amine or piperazine or substituted piperazine or amino acid with the protected carboxyl or polypeptide; and the Esculentoside A, EsA is obtained by separation and purification. The Esculentoside A, EsA, as well as pharmaceutical salt and medical composite thereof can be used for preparing inflammatory medicaments.

Dolomite wet process comprehensive utilization technique

The invention discloses a process of wet comprehensive utilization of dolomite, more specifically relates to a process for wet treatment of the dolomite to produce calcium and magnesium products, namely, the dolomite or incinerated dolomite powder is directly leached with sulfate acid to separate the calcium and the magnesium in the dolomite. The calcium precipitates in the form of calcium sulfateand the magnesium enters a solution in the form of magnesium sulfate; then magnesium hydroxide and calcium sulfate products are prepared from the magnesium solution after metathetical reaction and neutralization reaction. The intermediate product, calcium chloride, of the invention can be recycled, so the process is basically free of three-waste discharge and has notable environmental benefit; the invention, besides, significantly lowers the resource consumption and has obvious economic benefit.

Application of esculentoside A in preparing medicament for preventing or treating pulmonary fibrosis

The invention relates to the technical field of medicine, in particular to Phytolacca acinsa, the time-honored traditional Chinese medicine. The main active component of Esculentoside is Esculentoside A, EsA), which is a favorable COX-II (cyclooxygenase-2) inhibitor having good effects on inhabiting inflammatory response. The invention aims to provide the novel application of EsA in the preparation of medicine for preventing or treating pulmonary fibrosis. According to pharmacological tests, the EsA of the invention can obviously resist forming the fibrosis of lung tissues, therefore, the invention is applicable in preventing and treating the related diseases and has a good prospect of medicine application.