System and method for biphasic transdermal iontophoretic delivery of therapeutic agents

Various embodiments provide methods and systems for the biphasic iontophoretic transdermal delivery of therapeutic agents. An embodiment of a method for such delivery comprises positioning at least one electrode assembly in electrical communication with a patient's skin. The assembly includes a solution comprising a therapeutic agent which passively diffuses into the skin. A dose of agent is delivered from the assembly into the skin during a first period using a first current having a characteristic e.g., polarity and magnitude, to repel the agent out of the assembly. During a second period, a second current having a characteristic to attract the agent is used to retain the agent in the assembly such that delivery of agent into skin is minimized. A dose of agent may be delivered on demand by an input from the patient. Embodiments may be used for delivery of agents which cause adverse effects from unwanted passive diffusion.

System and method for biphasic transdermal iontophreotic delivery of therapeutic agents

Various embodiments provide methods and systems for the biphasic iontophoretic transdermal delivery of therapeutic agents. An embodiment of a method for such delivery comprises positioning at least one electrode assembly in electrical communication with a patient's skin. The assembly includes a solution comprising a therapeutic agent which passively diffuses into the skin. A dose of agent is delivered from the assembly into the skin during a first period using a first current having a characteristic e.g., polarity and magnitude, to repel the agent out of the assembly. During a second period, a second current having a characteristic to attract the agent is used to retain the agent in the assembly such that delivery of agent into skin is minimized. A dose of agent may be delivered on demand by an input from the patient. Embodiments may be used for delivery of agents which cause adverse effects from unwanted passive diffusion.

Novel tricyclic compounds

NOVEL TRICYCLIC COMPOUNDS Abstract N'N The invention provides compounds of Formula (I) and Formula (II), pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.

A rotary contact lens case

This invention discloses a rotary contact lens case, including a case body (10), and the case body (10) is provided with a rotating cavity (11); a rotating block (13) is rotatably arranged in the rotating cavity (11) by a spline shaft (50); a cavity (45) which opens leftwards is arranged in the rotating block (13); a second side of the rotating cavity (11) is provided with a closing device (200) which is used for closing the cavity (45); four of open cavities (14) which open outwards are uniformly distributed in an outer side of the cavity (45); open boxes (15) are slidably arranged in the open cavities (14); The invention is simple in structure and convenient to operate. The rotating block is rotated to make the required open boxes rotate to be opposite to the through cavity and the open boxes automatically opened, so that it is convenient to directly take out the contents inside the open boxes, and the device is small in size and convenient to carry. 1 11211 A 3 0 - 6 Figur -500 t -53 ...

5-HETEROARYL SUBSTITUTED INDAZOLES AS KINASE INHIBITORS

The present invention relates to compounds of formula (I) or pharmaceutic al acceptable salts, wherein A, R1, R2, R3 and m, are defined in the descrip tion. The present invention relates also to methods of making said compounds , and compositions containing said compounds which are useful for inhibiting kinases such as Glycogen Synthase kinase 3 (GSK-3), Rho kinase (ROCK), Janu s Kinases (JAK), AKT, PAK4, PLK, CK2, KDR, MK2, JNK1, aurora, pim 1 and nek 2.

METHOD AND SYSTEM FOR REMEDYING SENSOR MALFUNCTIONS DETECTED BY ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY

A method and system that enables a user to maintain a sensor in real time. The present invention involves performing a diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure to measure sensor impedance value in order to determine if the sensor is operating at an optimal level. If the sensor is not operating at an optimal level, the present invention may further involve performing a sensor remedial action. The sensor remedial action involves reversing the DC voltage being applied between the working electrode and the reference electrode. The reversed DC voltage may be coupled with an AC voltage to extend its reach.

AMINOPYRROLIDINES AS CHEMOKINE RECEPTOR ANTAGONISTS

The present invention is directed to novel aminopyrrolidines of formula ( I), pharmaceutically acceptable salts thereof, metabolites thereof, isomers thereof, stereoisomers thereof or pro-drugs thereof, wherein the variables a re as defined herein. The compounds of formula (I) are useful as chemokine r eceptor antagonists and as such would be useful in treating certain conditio ns and diseases, especially inflammatory conditions and diseases and prolife rative disorders and conditions, for example, cancers.

NOVEL TRICYCLIC COMPOUNDS

The invention provides a compound of Formula (I), pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.

ELECTRODEIONIZATION APPARATUS AND LOW SCALE POTENTIAL WATER TREATMENT

... ²Electrodeionisation devices having low scale potential as well water treatment ²methods ²using the device are disclosed. The device may have a variety of ²configurations such as a ²first depleting compartment disposed between the anode compartment and the ²cathode ²compartment, a concentrating compartment in ionic coummunication with the ²depleting ²compartment, a second depleting compartment in ionic communication with the ²concentrating compartment and a first barrier cell in ionic communication with ²and ²disposed between the first depleting compartment and at lest one of the anode ²compartment and the cathode compartment. The device may also have ²configuration ²directed to the layering of the anionic exchange resin beads and/or have at 1-²east one ²compartment that provides a dominating resistance resulting in a uniform ²current ²distribution throughout the apparatus. Temperature control may be provided. It ²is also ²possible to arrange for parallel liquid flow.² ...

TREATMENT OF PARAFFIN EMBEDDED TISSUE FOR GENE ANALYSIS

Rapid and easy preparation of a sample for a gene analysis or high-purity nucleic acid suitable for gene amplification especially, for example, by the PCR method is made possible by a process for treating a paraffin-embedded tissue sample to be used for a gene analysis, which comprises heating an aqueous suspension containing a surfactant having a protein-denaturational action and a deparaffinized tissue sample obtained from a paraffin-embedded tissue sample at 60.degree.C or higher, or the above-mentioned process which further comprises reacting the heat-treated aqueous solution with a protease, or the above-mentioned process which further comprises reacting the heat-treated aqueous solution with a protease, mixing the resulting reaction solution with a solution containing an organic compound having a protein-denaturational action other than the aforesaid surfactant, and precipitating nucleic acid from the resulting reaction solution by addition of an alcohol.

Anode material--lithium nickelate cobalt for lithium ion battery and preparation method thereof

The invention is a method of preparing lithium ion cell anode material-nickel cobalt acid lithium, and its characteristic: in the proportion of its formula, A-group matters: water-soluble lithium salt which is one of the lithium chloride, lithium sulphate, lithium nitrate and lithium acetate, water cobalt salt which is one of the cobalt chloride, cobalt sulphate, cobalt nitrate and cobalt acetate, and water nickel salt which is one of the nickel chloride, nickel sulphate, nickel nitrate and nickel acetate, the molar ratio of the three matters is 1.00-1.1 : 0.2-0.3 : 0.8-0.7; B-group matters: complexant is one of the oxalic acid, tartaric acid, citric acid, succinic acid, malonic acid, and maleic acid; the molar ratio of A to B is 1.0 : 0.6 -0.8; C-group polymers: gelatin, modified starch and polyvinyl alcohol. The beneficial effects: it can effectively reduce cost and the made LiNi1-yCoyO2 has the advantages of both LiCoO2 and LiNiO2, i.e. easy to synthesize, stable-property, high-specific ...

Bonding glue for sealing of pipelines

The invention relates to bonding glue for sealing of pipelines. The bonding glue for sealing of pipelines is made of the following raw materials in parts by weight: 8-16 parts of polybutadiene rubber, 3-8 parts of stearic acid, 5-10 parts of 35% chlorinated paraffin, 2-8 parts of white carbon black, 6-11 parts of chlorinated polyvinyl chloride resin, 5-7 parts of dichloromethane, 2-6 parts of silicon micropowder, 3-7 parts of iron oxide black, 5-9 parts of polyamide wax, 6-11 parts of vinyl trimethoxysilane, 2-4 parts of phosphoric acid, 3-6 parts of triethanolamine, 4-10 parts of acrylic emulsion, 2-6 parts of silicon carbide and 2-8 parts of surfactant. The bonding glue for sealing of pipelines disclosed by the invention has the advantages of excellently sealing pipelines and having good resistance against corrosion, acid and alkali.

Methods and devices for coding and decoding digital audio signals

The invention discloses methods for coding and decoding digital audio signals, belonging to the technical field of digital signal coding. The methods are characterized by decomposing MCLT (modulated complex lapped transform) and IMCLT (inverse modulated complex lapped transform) matrixes with the length of 2M into two MCLT and IMCLT matrixes with the length of M respectively to be rapidly calculated when the digital audio signals are coded or decoded, thus reducing the calculation complexity. Compared with the prior art, the methods have the advantages of low calculation complexity, good real-time performance and easiness in implementation. The invention also discloses devices for coding and decoding digital audio signals. The devices adopt the methods.

Side slope stock and soil nail draw testing arrangement

The utility model discloses a side slope stock and soil nail draw testing arrangement, include: the bottom plate, swing joint is served to bottom plate no. 1 has the loading board, swing joint has 1 at least fagging on the loading board, the one end swing joint of fagging on the loading board, the other end and bottom plate looks joint, be provided with the jack on the loading board, be provided with stock or soil nail on the jack, stock and soil nail and loading board are vertical position. In this way, the utility model discloses side slope stock and soil nail draw testing arrangement, the bearing capacity that can adjust the different angles various slopes of adaptation and angle detects, prevents eccentric state, and easy dismounting is small, and the testing result is accurate.

Solar lamp utensil of maintenance easy to assemble

The utility model discloses a solar lamp utensil of maintenance easy to assemble, its characterized in that: include: shell (1), lamps and lanterns (2) and set up in battery (3) in shell (1), the upper surface of polygon lamps and lanterns top cap (4) is provided with annular groove (9), is used for fixing the installation end of lamps and lanterns bracing piece (10) of shell (1) is provided with annular chimb (11), annular chimb (11) is put into annular groove (9) cover the back by a plurality of bolt fastenings by annular apron (12) again. The utility model provides a pair of solar lamp utensil of maintenance easy to assemble has realized the detachable installation of solar lamp utensil, and be convenient for installation and maintenance are maintained, long service life, and simple structure, it is with low costs.

Solar panel automatically cleaning formula solar lamp utensil

The utility model discloses a solar panel automatically cleaning formula solar lamp utensil, its characterized in that: include: shell (1), lamps and lanterns (2) and set up in battery (3) in shell (1), battery (3) with lamps and lanterns (2) ferroelectric phase even, battery (3) are still passed shell (1) links with solar panel (9) ferroelectric phase, solar panel (9) are located the top of shell (1) just is fixed in on shell (1), be provided with brush (10) and dog (11) on solar panel (9), the one end activity of brush (10) set up in the base middle part of solar panel (9), dog (11) set up in the base both ends of solar panel (9). The utility model provides a pair of solar panel automatically cleaning formula solar lamp utensil makes solar panel fully absorb light, has improved the use of solar energy efficiency greatly, has further realized energy saving and emission reduction.

Three-dimensional electrical sounding method

The invention provides a three-dimensional electrical sounding method which includes the following steps: (1) measuring electrode arrays are arranged in a ground to-be-measured area according to a rectangular or square measurement grid; (2) all non-polarizing electrodes of measurement lines are sequentially connected with binding posts of a control panel of a measurement way respectively; (3) the control panel of the measurement way is connected with multiple electrical prospecting apparatuses; (4) a current electrode set is arranged; (5) any current electrode is selected for electrification, and the apparent resistivity and the apparent polarizability of each measurement point are calculated; (6) current electrode couples in the step (5) are powered off and replaced by another set of current electrodes with different electrode distances, the control panel of the measurement way is adjusted, electrodes at the measurement points are sequentially connected with the multiple electrical prospecting ...

Coating rubber roller for high-grade automobile plate production line and manufacturing method thereof

The invention discloses a coating rubber roller for a high-grade automobile plate production line and a manufacturing method thereof, belonging to the field of rubber rollers and preparation methods thereof. The rubber for the rubber roller comprises the following components in percentage by weight: 50.7-58.1% of ethylene-propylene rubber, 29.1-38.1% of carbon black, 2.5-2.9% of naphthenic oil, 2.5-2.9% of ester oligomer, 2.5-2.9% of tackifier, 1.0-1.2% of flow promoter, 1.9-2.2% of vulcanizing agent DCP, 0.28-0.32% of sulfur, 0.18-0.20% of accelerator BZ and 0.18-0.20% of accelerator DPTT. The method comprises the following steps: compounding the rubber; winding and rubberizing; vulcanizing in a vulcanizer; and carrying out lathe grinding. In the rubber compounding process, the materials can be sufficiently dispersed and fused. the rubberizing grain color difference on the roller surface can be eliminated, the consistency of internal and external hardness of the rubber roller is high, ...

Double-layer stacking, vacuum packaging and opening sealing device and method

The invention discloses a double-layer stacking, vacuum packaging and opening sealing device and method. The device is provided with a vacuum chamber, wherein a first opening sealing heating strip and a second opening sealing heating strip are respectively arranged on the two sides of the vacuum chamber. The device further comprises a first layering unit and a second layering unit, wherein the first layering unit is used for placing a first to-be-packaged duck and enabling the first opening sealing heating strip to carry out opening sealing operation on the first to-be-packaged duck; the second layering unit is arranged on the first layering unit, and is used for placing a second to-be-packaged duck and enabling the second opening sealing heating strip to carry out opening sealing operation on the second to-be-packaged duck. The device has the advantages that on one aspect, heating opening sealing can be rapidly carried out respectively on the to-be-packaged ducks, food weight reduction ...

Textile type artificial blood vessel water permeability test equipment and its testing method

Rotary transformer initial position signal autocorrection method

The invention discloses a rotary transformer initial position signal autocorrection method, which realizes stator vector orientation through software, calculates the average value after multiple positions and multiple angles are tested. The method of the invention not only reduces the cost, but also improves the rotary transformer initial position signal autocorrection accuracy.

一种升频升压型步进电机的驱动方法

... 本发明涉及一种升频升压型步进电机的驱动方法，以克服目前升频升压控制所存在的问题，将电流控制技术与升频升压技术结合，以提高驱动器电压和电流的可控制性，从而提高驱动性能及可靠性。本方法首先将外部步进脉冲信号和方向信号转换成功率转换控制信号，将外部控步进脉冲信号的频率转换成电压信号，将由功率变换产生的电流进行检测，与电压信号进行比较及脉宽调制处理，产生电流控制信号，该信号与通电顺序控制信号共同放大合成，产生控制功率变换的信号，从而将直流电压调制成为能够控制电机的电压。本发明实现了闭环升频升压控制和升频升流控制，提高了电机控制的可靠性和灵活性。 ...

Improvement of 1,6-hexaaldehyde purity

Phase insulation structure of centralized coiling electric motor for compressor

The invention relates to an alternative insulting structure of a centralized winding motor used for a compressor; the alternative insulating structure includes a welding joint bushing and a slot wedge supporting the welding joint bushing. The welding joint bushing is formed by coiling insulating materials for one to six circles and one end is melt by ultrasonic; the mother plate of the slot wedgeis rectangle insulating paper which is folded into a V shape with two longer side wings and shorter folded ridge by three times. The invention has the advantage that the use of the insulating materials is reduced; the welding joint bushing plays the role of alternative insulation simultaneously when protecting the welding joint by being inserted into the slot; besides, the height of the end part of an educing side winding increased by binding the welding joint bushing in the existing insulating structure is reduced.

Automatic machining detection device for motor end cover

The utility model relates to an automatic machining detection device for a machine end cover and a using method thereof. Several production lines, each production line comprises a to-be-machined material warehouse, a truss manipulator, a first numerical control lathe, a second numerical control lathe, a three-coordinate detector, a machining center and a finished product material warehouse. A to-be-machined material bin is arranged at the right end of the truss manipulator. A finished product warehouse is arranged at the left end of the truss mechanical arm, the truss mechanical arm comprisesa truss and at least one picking unit, the truss is arranged between the to-be-machined warehouse and the finished product warehouse, and a first numerical control lathe, a second numerical control lathe, a three-coordinate detector and a machining center are sequentially arranged on one side of the truss in the direction from the to-be-machined warehouse to the finished product warehouse. The utility ...

Fresh-keeping method of fresh myrciaria cauliflora

The invention discloses a preservation method of fresh myrciaria cauliflora fruits, which comprises the following steps: (1) picking the myrciaria cauliflora fruits, flatly laying the myrciaria cauliflora fruits at room temperature, deleting field heat, and removing the fruits with mechanical injury and pest and disease damage; (2) adding 100-1000 [mu] L/L edible alcohol into a watch glass, putting the watch glass below a grid at the bottom of a closed container, putting the jaboticaba on the grid, and carrying out fumigation treatment with the fumigation amount controlled within 80% of the container; (3) the fumigation temperature is controlled to be 20-30 DEG C, and the fumigation time is controlled to be 1-7 h; (4) after fumigating, taking out and airing, and deleting the fumigant ethanol; and (5) storing at 0-4 DEG C. By using an alcohol fumigation and low-temperature combined fresh-keeping technology, the synthesis of ethylene, the breathing rate and the like of the jaboticaba fruits ...

Tunnel wind speed detection method and system based on TOF and computer equipment

The invention relates to the technical field of mine ventilation detection, in particular to a TOF (Time of Flight)-based roadway wind speed detection method, which comprises the following steps: S1, an ultrasonic anemograph is mounted on a rock wall in a roadway, the ultrasonic anemograph comprises four ultrasonic transducers, and in the four ultrasonic transducers, two pairs of ultrasonic transducers forming an angle of 180 degrees are positioned on the same horizontal plane, and the two pairs of ultrasonic transducers are positioned on the same horizontal plane; the vertical distances between the two pairs of ultrasonic transducers and the ground are equal; s2, respectively calculating the down-wind and up-wind time of each pair of ultrasonic transducers through a dual cross-correlation filtering method; and S3, calculating the wind speed component of the roadway based on an ultrasonic time difference method. According to the TOF-based roadway wind speed detection method provided by ...

Bridge detection device with safety protection mechanism

The invention provides a bridge detection device with a safety protection mechanism, and relates to the technical field of bridge detection, the bridge detection device comprises a supporting part, and the supporting part is carried on the side wall of a bridge and can move in the length direction of the side wall of the bridge; the adjusting arm is connected to the side wall of the supporting component and suitable for synchronously sliding along with the supporting component, and one end of the adjusting arm extends to the position below the bridge; and the driving part comprises a horizontal sliding seat fixedly connected to one end of the adjusting arm, the inner side wall of the horizontal sliding seat is slidably connected with a moving rod, and the inner side wall of the horizontal sliding seat is fixedly connected with a driving motor. Through the arrangement of the supporting part, the adjusting arm, the driving part and the detection part, the supporting part can move on guardrails ...

Novel thienopyrrole compounds

The invention provides a compound of Formula (I) pharmaceutically acceptable salts, prodrugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.

TEMPO-SPATIAL EVOLUTION TEST SYSTEM FOR ROCK BREAKING IN DEEP AND COMPLEX ENVIRONMENT

A tempo-spatial evolution test system for rock breaking in deep and complex environment includes an acoustic emission sensor assembly and an acoustic emission amplifier assembly that are arranged on a rock mechanics test system. A triaxial cavity coupling bracket is arranged on an outer wall of the triaxial cavity and between two sets of acoustic emission sensor assemblies. The triaxial cavity coupling bracket includes a plate-shaped bracket, two sickle-shaped brackets, and at least three bracket bolts, which can be tightly wrapped on the outer wall of the triaxial cavity. A lateral side of the plate-shaped bracket vertically fixes two guide columns. The acoustic emission amplifier assembly is arranged between the two guide columns and is located above the plate-shaped bracket, and the acoustic emission amplifier assembly is connected to the acoustic emission sensor assembly through a signal line.

METHODS AND DEVICES FOR FACILITATING EMERGENCY CALLS OVER WIRELESS COMMUNICATION SYSTEMS

One embodiment of the present disclosure relates to a method implemented by a first gateway node for processing an emergency call from an untrusted non-3GPP access network. The method comprises: receiving an emergency call request initiated from a terminal device over an untrusted non-3GPP based access network; detecting an event of the emergency call depending upon the emergency network access identifier included in the request message; selecting for the terminal device an emergency access point name that identifies an external network providing an emergency call service; and establishing for the terminal device an emergency call session with a second gateway node interfacing with the external network which is identified by the selected emergency access point name. According to an aspect of the present disclosure, there are provided corresponding methods and devices.

Power supply circuit, controlling method and lighting device driver

A power supply circuit, a controlling method and a lighting device driver are provided. The power supply circuit includes: a voltage convertor circuit, configured to be input an input voltage and output an output voltage and an output current, the voltage convertor circuit having a primary side and a secondary side, the primary side having at least one switch unit which controls the primary side to rectify the input voltage, the secondary side outputting the output voltage and the output current; a voltage control circuit, configured to generate a constant voltage feedback signal, according to a current in the voltage convertor circuit; a current control circuit, configured to generate a constant current feedback signal, according to a voltage in the voltage convertor circuit; a controller, configured to generate a controlling signal to control the switch unit, according to the constant voltage feedback signal or the constant current feedback signal; and a selecting circuit, configured ...

SYSTEM AND PROCEDURE FOR SENSORREKALIBRIERUNG

Method for sequencing nucleic acids

An anti-dropping glasses case

This invention discloses an anti-dropping glasses case, including an upper cover (11), a lower cover (12) arranged at a bottom of the upper cover (11), an upper cavity (81) arranged in the upper cover (11), an upper fixing mechanism (100) arranged in the upper cavity (81), a lower cavity (71) arranged in the lower cover (12) and a lower fixing mechanism (200) arranged in the lower cavity (71). The overall structure of the glasses case is more reasonable and ingenious, and the locking mechanism is arranged in the glasses case. So that the matching between the upper cover and the lower cover of the glasses case is ensured and the safety of the glasses case is improved. Moreover, the fixing mechanisms are configured to improve the protection degree of the glasses, therefore the glasses case has high values of application and popularization.

Primary carboxamides as BTK inhibitors

PRIMARY CARBOXAMIDES AS BTK INHIBITORS Abstract H2N O Formula (I) The invention provides carboxamide compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereo isomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions, including rheumatoid arthritis, juvenile rheumatoid arthritis, osteoarthritis, Crohn's disease, inflammatory bowel disease, ulcerative colitis, psoriatic arthritis, psoriasis, ankylosing spondylitis, interstitial cystitis, asthma, systemic lupus erythematosus, lupus nephritis, B cell chronic lymphocytic lymphoma, multiple sclerosis, chronic lymphocytic leukemia, small lymphocytic lymphoma, mantle cell lymphoma, B-cell non-Hodgkin's lymphoma, activated B-cell like diffuse large B-cell, lymphoma, multiple myeloma, diffuse large B-cell lymphoma, follicular lymphoma, hairy cell leukemia or Lymphoblastic lymphoma.

An anti-overflow contact lens case

This invention discloses an anti-overflow contact lens case, including a case body (11); a soaking cavity (26) is disposed in the case body (11) and is provided with a water exchange tube (56) connected to the exterior; a locking apparatus (901) located at a lower end of the soaking cavity (26) is disposed in the case body (11); accessing grooves (33), communicated with each other, are symmetrically disposed on front and rear inner walls of the case body (11); accessing apparatuses (902) are disposed in the accessing grooves (33); beams (37) are disposed in the soaking cavity (26); The invention has simple structure, protects care solution while moving contact lens horizontally and steadily, and prevents the overflow of the care solution. 27 2,6 252423 A \l 01 Figure 1 ...

NICOTIANA-SPECIFIC MOLECULAR MARKER FOR DISCRIMINATING TOBACCO FROM NON-TOBACCO AND APPLICATION THEREOF

The present invention belongs to the field of molecular biotechnology. More specifically, it relates to a Nicotiana-specific molecular marker for discriminating tobacco from non-tobacco and application thereof. The numbers of the Nicotiana-specific molecular marker comprise Ntsp027 and Ntsp151, and the nucleotide sequences of the PCR amplified products thereof are shown in SEQ ID No .1 and SEQ ID No .2, respectively. The application is to use the Nicotiana-specific molecular markers as described above to perform PCR amplification on the genomic DNA of the tobacco raw material involved to detect whether there is a specific nucleotide sequence of the PCR amplified product, and to accurately determine whether tobacco materials are present in the tobacco raw material involved. The Nicotiana-specific molecular marker of the present invention realizes the rapid and effective identification and detection of tobacco and non-tobacco, improves the scientificity, accuracy and authority of the identification ...

DESIGN, MANUFACTURE, AND USE OF PERSONALIZED CANCER VACCINES

Personalized cancer vaccines are created by predicting whether a first neoantigen or a second neoantigen of an individual cancer patient has a stronger binding affinity for a human leukocyte antigen (HLA) complex of the patient and creating a particle containing the neoantigen with the stronger predicted binding affinity. Such a predicting step includes artificial intelligence, statistical modeling, or a combination thereof. Such a particle is created by encapsulating the neoantigen with the stronger predicted binding affinity for the HLA complex of the patient in a material. Placing the antigen in a particular sized particle is referred to here as Size Exclusion Antigen Presentation Control, (SEAPAC) used in methods of treating the patient using such a personalized cancer vaccine.

READY-TO-DRINK MILK BEVERAGES WITH IMPROVED TEXTURE/MOUTHFEEL BY CONTROLLED PROTEIN AGGREGATION, AND METHOD OF MAKING THEREOF

The present invention relates to beverage products. In particular, the invention is concerned with a protein system induced by controlled aggregation of milk proteins which imparts outstanding sensory attributes on beverage product, in particular when containing low fat and/or low sugar. A method of producing such beverage and the products obtainable from the method are also part of the present invention.

ANTIMICROBIAL GEL FORMULATIONS

Disclosed herein are formulations comprising an N-halogenated or N,N- dihalogenated amine compound dispersed in a water-swellable polymer, wherein the compound is 90% stable for at least 30 days at about 250C. Also disclosed are methods of treating or preventing infections caused by a bacterial, a microbial, a sporal, a fungal or a viral activity using such formulations.

NOVEL TRICYCLIC COMPOUNDS

The invention provides compounds of Formula (I) and Formula (II), pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.

MODIFIED SENSOR CALIBRATION ALGORITHM

A method of calibrating glucose monitor data includes collecting the glucose monitor data over a period of time at predetermined intervals, obtaining reference glucose values from a reference source that temporally correspond with the glucose monitor data obtained at the predetermined intervals, calculating the calibration characteristics using the reference glucose values and corresponding glucose monitor data to regress the obtained glucose monitor data, and calibrating the obtained glucose monitor data using the calibration characteristics. In additional embodiments, calculation of the calibration characteristics includes linear regression and, in particular embodiments, least squares linear regression. Alternatively, calculation of the calibration characteristics includes non-linear regression. Data integrity may be verified and the data may be filtered. Further, calibration techniques may be modified during a fast rate of change in the patient's blood glucose level to increase sensor ...

REAL-TIME SELF-CALIBRATING SENSOR SYSTEM AND METHOD

Integrated blasting recorder and working method thereof

The present invention is suitable for the blasting monitoring technology field, and provides an integrated blasting recorder and a working method thereof. The integrated blasting recorder comprises a recorder host and a mobile terminal which are in wireless communication connection. The recorder host comprises a shell, and a three-shaft sensor, an acquisition circuit, a communication unit, a data processing unit, a memorizer and a power supply for supplying power to the recorder host are arranged in the shell. The mobile terminal is used to record the working parameter of the recorder host, check a blasting file in the recorder host and display the file with figures, and the recorder host is used to record the vibration data according to the working parameters, and generate the blasting file. The integrated blasting recorder of the present invention enables the sensor, the host and the power supply to be integrated together, is compact in size, is convenient to carry and simple to operate ...

Searching method and searching server

The embodiment of the invention provides a searching method and a searching server, wherein the method comprises the steps as follows: obtaining enterprise search terms submitted by user equipment; determining a preset function plug-in unit corresponding to a target keyword if the enterprise search terms correspond to the target keyword; showing the function plug-in unit in a set area of a search result page when the search result page shows a search result matched with the enterprise search terms. In the embodiment of the invention, a user can check information that he is interested in via the function plug-in unit showed in the search result page. The searching method and the searching server of the invention can be used for reducing further searching times after the user checks the search result matched with the enterprise search terms so as to simplify the operation of the user and improve search experience of the user.

Internet-of-things system of building electric device

The invention relates to an Internet-of-things system of a building electric device. The system comprises at least one building, wherein each building is provided with at least one data management computer, the data management computer utilizes the Ethernet to connect with the computers of a data management center; the data management computer is communicated with a mobile phone terminal through a wireless communication network and is connected with a remote control terminal through the wide area network; the inside of the building is provided with a plurality of room units, the inside of each room unit is provided with at least one environmental module, at least one room controller and at least one device wireless monitoring and controlling module; the inside of each room unit is provided with at least one building electric device, the building electric device is connected with the corresponding device wireless monitoring and controlling module; a group of sensors are integrated in the ...

Heat-resistant alloy for ultra-supercritical thermal power steam turbine sets

The invention relates to a heat-resistant alloy for ultra-supercritical thermal power steam turbine sets, belonging to the technical field of heat-resistant alloys. The heat-resistant alloy comprises the following chemical components in percentage by weight: 0.005-0.1% of C, 30-40% of Ni, 15-25% of Cr, 1.0-5.0% of Al+Ti, 0.01-2.0% of Nb, 0.001-0.2% of V, 0.001-0.004% of B, 0.001-0.02% of Ce, 0.01-1% of Cu, 0.01-0.3% of Si, 0.001-0.05% of Mn, 0.01%max of S, 0.01%max of P and the balance of Fe. The heat-resistant alloy can be used for long-term service heat-resistant components in a 650-700 DEG C parameter high-temperature combustible gas or steam corrosion environment. The cost is obviously lowered than that of the nickel-base alloy.

Processing method and processing system of novel component-based network protocol

The invention discloses a processing method and a processing system of a novel component-based network protocol, belonging to the technical field of computer network. The processing method comprises the following steps: firstly, establishing a component base and a component information base; then determining needed component transfer sequence according to a network service request by a component adapter of a source node, and sequentially transferring corresponding component structures to complete a packet header of a data packet needed by members and then sending the data packet; if a receiving node is an intermediate node, transmitting the data packet to a next hop node; if the receiving node is a target node, sequentially reading information inside the packet header of the received data packet by the component adapter, and transferring the matched components according to the information of the packet header to explain the information of the packet header so as to complete the network ...

Accurate testing method for gravity heat pipe non-condensable gas quantity

The invention belongs to the technical field of fluid loop ground tests, and particularly relates to a testing device for non-condensable gas quantity, in particular to an accurate testing method for gravity heat pipe non-condensable gas quantity. The testing method comprises the following steps: step A, vertically putting a gravity heat pipe in a vacuum chamber (1), wherein the upper part of a pipeline (15) of the gravity heat pipe is attached to a cold plate (9) inside the vacuum chamber (1); step B, after standing for a period of time, vacuumizing the vacuum chamber (1); step C, reducing the temperature of the gravity heat pipe to a set temperature through the cold plate, and meanwhile carrying out radiation heat transfer on the gravity heat pipe and the vacuum chamber (1); step D, when the temperature of the gravity heat pipe is balanced, collecting the temperature of a temperature measure point on the gravity heat pipe by an infrared thermometer (7), and calculating the non-condensable ...

Method for manufacturing thin film solar cell and thin film solar cell

The invention provides a method for manufacturing a thin film solar cell and the thin film solar cell. The method for manufacturing the thin film solar cell comprises the steps that a first electrode is formed on a substrate; an N type doping layer and an intrinsic semiconductor thin film are formed on the first electrode; ion injection is conducted on the intrinsic semiconductor thin film, and activation is conducted on the intrinsic semiconductor thin film subject to ion injection according to the excimer laser annealing (ELA) technology, so that a P type doping layer is formed on the upper layer of the intrinsic semiconductor thin film; a second electrode is formed on the P type doping layer. Due to the fact that the technological range can be accurately controlled through the ELA technology, only the portion, which is within the technological range and used for forming the P type doping layer, of a semiconductor thin film is heated rapidly, the temperature gradient is large, the substrate ...

Method for inversion of ocean surface wind direction through navigation radar images on basis of self-adaptation diminishing operator

The invention discloses a method for inversion of an ocean surface wind direction through navigation radar images on the basis of a self-adaptation diminishing operator. The method includes the following steps that N navigation radar images are collected to form a navigation radar image sequence; median filtering is carried out on the navigation radar images; azimuth normalization is carried out on the navigation radar images after median filtering, and the line number of the azimuth of each filtered navigation radar image is fixed; global low-pass filtering is carried out on the navigation radar images after azimuth normalization to obtain ocean surface static feature images containing wind streaks; according to the ocean surface static feature images, ocean surface wind direction inversion is carried out to obtain an ocean surface wind direction. A self-adaptation algorithm is designed, whether diminishing resolution and the size of the wind streaks are proper can be judged according ...

Bituminous mixture water stability unipolar test device

The utility model discloses a bituminous mixture water stability unipolar test device, including test container, rigidity depression bar, rigidity pressure disk and rubber suction cups, be provided with fixing device in the test container, the last test piece that is fixed with of fixing device, rigidity bar connection has servo mechanism, the vertical connection rigidity depression bar in rigidity pressure disk upper end, the vertical connection rubber suction cups of lower extreme, the vertical test piece that acts on of rubber suction cups. Utilizing rubber suction cups direct contact bituminous mixture test piece under the servo mechanism effect, truly simulating the motion state of moisture in bituminous mixture, the water stability that detects sum check bituminous mixture can, test device simple structure, the equipment is easy, and test conditions satisfies easily, test device is unipolar test device, and the atress is directly clear and definite, and the accuracy is higher.

Positive plate of high power lithium ionic cell and lithium ionic cell containing the same

The invention relates to the technical field of lithium ion batteries, in particular to a high-power lithium ion battery positive plate and a lithium ion battery thereof. The invention discloses a high-power lithium ion battery positive plate, which comprises a current collector and cathode material, wherein the cathode material comprises positive active substances, bonding agent and conductive agent, and is characterized in that the positive active substance is formed by layered lithium cobalt oxide and layered nickel cobalt lithium manganese oxide, and the proportion by weight of lithium cobalt oxide and nickel cobalt lithium manganese oxide is 1-7:1-9. The invention further provides a lithium ion battery which contains the positive plate. The invention solves the problems of bad heavy-current discharge and poor performance high circulation generated after layered nickel cobalt lithium manganese oxide material is used on a high-power lithium ion battery owing to the weaknesses existing ...

C 4 olefin desulfurization absorbent and production method and use thereof

The invention relates to an adsorbent for deep desulfurization of materials containing C4 olefin, a preparation method and application thereof. The adsorbent for desulfuriztion consists of reduced VIII transition metal, reduced IB transition metal and IIB transition metal oxide which activate sulfur-containing molecules, and adhesive taking alumina as a main component. The adsorbent can adsorb nearly all sulfur compounds in the materials containing C4 olefin to get the materials containing C4 olefin with sulfur content lower than 5ng/mu l.

Aquatic organism electronic specimen making table

The aquatic organism electronic specimen making table comprises a main body plate, a protective cover is hinged to the upper side of the main body plate, sealing strips are symmetrically distributed and fixedly installed on the outer wall of the side, close to the main body plate, of the protective cover, and an elastic buckle is fixedly installed in the center of the outer wall of the side, close to the main body plate, of the protective cover; a plurality of movable rods are symmetrically distributed and hinged to the top end of the inner wall of the protection cover, fixed ring frames are symmetrically distributed and fixedly installed in the center of the top end of the inner wall of the protection cover, a searchlight is hinged to the tail end of one movable rod, a magnifying lens is hinged to the tail end of the other movable rod, and a storage box is fixedly installed on one side of the upper surface of the main body plate. Spring sleeves are symmetrically distributed and fixedly ...

Full-automatic transfer printing equipment for curtain fabric

The invention discloses full-automatic transfer printing equipment for curtain fabric, and relates to the technical field of transfer printing equipment, the full-automatic transfer printing equipment comprises a main body mechanism, a fabric decontamination mechanism is slidably embedded in the inner surface wall of the main body mechanism, and an ink supply mechanism is fixedly mounted at the top of the main body mechanism. According to the curtain fabric transfer printing device, firstly, under rotation of the two transfer printing rollers, transfer printing treatment can be conducted on curtain fabric, an ink supply mechanism at the top can provide raw materials for the curtain fabric, and therefore continuous work of the curtain fabric is guaranteed, and after transfer printing is completed, patterns on the outer surface wall of the fabric have the high temperature condition, and the fabric cannot be damaged; when cloth passes through the bottom of the cooling mechanism, the cooling ...

Electric power metering equipment operation maintenance method and device, terminal and storage medium

The invention relates to the technical field of electric power metering, in particular to an electric power metering equipment operation maintenance method and device, a terminal and a storage medium, and the method comprises the steps: firstly obtaining a plurality of class attributes corresponding to a plurality of metering equipment; then, according to a plurality of metering databases corresponding to the plurality of metering devices, obtaining a plurality of aging feature sets corresponding to the plurality of metering devices; then, inputting the plurality of aging feature sets into a plurality of aging models respectively, and obtaining a plurality of aging estimated values corresponding to the plurality of metering devices; and finally, determining a maintenance target according to a threshold value and the plurality of aging estimation values. According to the embodiment of the invention, maintenance can be carried out before the metering equipment is aged to a certain degree, ...

Train, emergency power supply control method and system thereof and vehicle control unit

The invention discloses a train and an emergency power supply control method and system thereof. The method comprises the steps that battery real-time allowable discharging states sent by BMS of all carriages are obtained; when it is determined that any compartment does not allow battery discharging according to the real-time battery discharging allowing states sent by the BMS of all the compartments, the compartment is controlled to be subjected to high-voltage discharging; after it is determined that the carriage completes high-voltage electricity withdrawing, the carriage adjacent to the carriage is controlled to conduct auxiliary electricity withdrawing; after it is determined that the carriage adjacent to the carriage completes auxiliary power-off, the auxiliary load of the carriage is controlled, the auxiliary load of the carriage adjacent to the carriage is connected into a through loop, and an auxiliary power-on instruction is sent to the BMS of the carriage adjacent to the carriage ...

Independent heat dissipation energy-saving control method and device for engineering machinery

The invention discloses an independent heat dissipation energy-saving control method and device for engineering machinery. The method comprises the steps that the current temperature value of a controlled object in the engineering machinery is collected; and when the engineering machinery enters an idling operation state, comparing the acquired current temperature value with a set high-temperature critical value, if the acquired temperature value is greater than the set high-temperature critical value, not entering the independent heat dissipation idling control logic, otherwise, entering the independent heat dissipation idling control logic. According to the operation condition of the engineering machinery and the temperature value collected by the independent heat dissipation system, the heat dissipation control logic can be automatically adjusted, the heat dissipation power is effectively reduced, and fuel waste is avoided.

Three-phase relay protection tester protection device

The invention belongs to the technical field of nuclear power, and particularly relates to a three-phase relay protection tester protection device. The invention discloses. According to the invention, the bottom of a three-phase relay protection tester is fixedly connected with a base box, two sides of the top of the base box are fixedly provided with top plates through buffer mechanisms, the bottoms of the top plates are attached to the top of the three-phase relay protection tester, and one side of the three-phase relay protection tester is provided with a plurality of test power connection ports. According to the invention, when the handle is pulled to drive the top plate and the bottom three-phase relay protection tester to move and the base box generates vibration in the moving process, the base box can drive the peripheral buffer rods to move, the buffer rods can drive the top mounting plate to move, and the mounting plate can drive the bottom telescopic rod to extend. The telescopic ...

Portraying method, system and equipment and storage medium

The embodiment of the invention discloses a portraying method, system and device and a storage medium. The method comprises the steps of obtaining user data from various social networks or data platforms; dividing to form an explicit community and an implicit community according to different user data; and respectively portraying the explicit community and the implicit community based on user data in combination with different community portraying methods to form community portraits. According to the embodiment of the invention, real-time and comprehensive modeling is carried out on various community data, and a panoramic dynamic community portrait is constructed; on the other hand, data support is provided for applications such as semantic search, intelligent question and answer, a recommendation system, data visualization, big data analysis and decision making and the like; and on the other hand, accurate community discovery is guided by enriching community node semantic information, ...

Novel tricyclic compounds

The invention provides a compound of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.

Data caching method and storage medium

The data caching method and a storage medium includes acquiring, by receiving the request of caching service data sent by the UE, the network status data between an SBS corresponding to UE and the UE, the network status data between an MBS corresponding to the SBS and the UE, and the network status data between the UE and a data source of the service data. According to the types of the three pieces of network status data and the service data, three corresponding QoE values are acquired, and whether the cache is configured for the UE is determined according to the three QoE values. The quantification of the three QoE values is realized, and whether the cache is configured for the UE is determined according to the quantized QoE values, thereby achieving the effect of improving the quality of user experience.

System and method for biphasic transdermal iontophoretic delivery of therapeutic agents

Various embodiments provide methods and systems for the biphasic iontophoretic transdermal delivery of therapeutic agents. An embodiment of a method for such delivery comprises positioning at least one electrode assembly in electrical communication with a patient's skin. The assembly includes a solution comprising a therapeutic agent which passively diffuses into the skin. A dose of agent is delivered from the assembly into the skin during a first period using a first current having a characteristic e.g., polarity and magnitude, to repel the agent out of the assembly. During a second period, a second current having a characteristic to attract the agent is used to retain the agent in the assembly such that delivery of agent into skin is minimized. A dose of agent may be delivered on demand by an input from the patient. Embodiments may be used for delivery of agents which cause adverse effects from unwanted passive diffusion.

System and method for sensor recalibration

A system and method for calibrating a sensor. The method may include, without limitation, compiling an array of data relating to the sensor; adjusting a sensor parameter a first time based on data in the array; adjusting a curve representing the sensor output based on data in the array; and adjusting the sensor parameter a second time based on data in the array. The sensor may be an in vivo glucose sensor and the sensor parameter adjusted may be a current. The array may include historical as well as recent data, such as, for example, blood glucose readings and sensor electrode readings.

AUTOMATIC PERFORMANCE ANALYSIS AND ERROR CORRECTION

5-heteroaryl substituted indazoles as kinase inhibitors

A glasses case with a cleaning capability

This invention discloses a glasses case with a cleaning capability, including a base 40, a seating cavity 39 opening upward, a spin-drying device 901, a glasses cover 10, locking devices 902, a cleaning cavity 11 opening downward and a release device 903 of longitudinal symmetry. The present invention is simple in structure. The cleansing solution is sprayed at the time of cleaning to achieve high-efficiency cleaning; in addition, based on a principle of centrifugal force, the cleansing solution in the glasses frame is spin-dried and blown dry by an encircling blower, thus ensuring that the glasses are clean and clear before the next use.

TRICYCLIC COMPOUNDS

... ²The invention provides a compound of Formula (I)²pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, ²stereoisomers and ²isomers thereof wherein the variable are defined herein. The compounds of the ²invention are useful ²for treating immunological and oncological conditions.²(See above formula)² ...

METHOD AND SYSTEM FOR REMEDYING SENSOR MALFUNCTIONS DETECTED BY ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY

A method and system that enables a user to maintain a sensor in real time. The present invention involves performing a diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure to measure sensor impedance value in order to determine if the sensor is operating at an optimal level. If the sensor is not operating at an optimal level, the present invention may further involve performing a sensor remedial action. The sensor remedial action involves reversing the DC voltage being applied between the working electrode and the reference electrode. The reversed DC voltage may be coupled with an AC voltage to extend its reach.

SYSTEM AND METHOD FOR SENSOR RECALIBRATION

A system and method for calibrating a sensor. The method may include, without limitation, compiling an array of data relating to the sensor; adjusting a sensor parameter a first time based on data in the array; adjusting a curve representing the sensor output based on data in the array; and adjusting the sensor parameter a second time based on data in the array. The sensor may be an in vivo glucose sensor and the sensor parameter adjusted may be a current. The array may include historical as well as recent data, such as, for example, blood glucose readings and sensor electrode readings.

Acoustic surface wave gas sensor with three-dimensional nano structure

The invention relates to an acoustic surface wave gas sensor with a three-dimensional nano structure. The acoustic surface wave gas sensor comprises a piezoelectric substrate, an input interdigital electrode IDT 1 (interdigital transducer 1) and an output interdigital electrode IDT 2 which are arranged on the surface of the piezoelectric substrate and are mutually parallel, and a sensitive area, wherein the sensitive area is located between the interdigital electrode IDT 1 and the interdigital electrode IDT 2, a three-dimensional nano structure sensitive film is arranged on the sensitive area, and comprises a modified three-dimensional nano wire or nano pipe growing on the sensitive area, and a sensitive film applied to the surface of the sensitive area, and the sensitive film is attached to the outer surface of the three-dimensional nano wire or nano pipe. The gas sensor is high in integration degree, small in size, light in weight, low in cost, wide in application range, capable of working ...

Environment-friendly floor adhesive

The invention discloses an environment-friendly floor adhesive prepared from the following raw materials in parts by weight: 2.3-4.6 parts of dihydroxylpolymethylvinyl siloxane, 1.5-3 parts of sodium pentachlorophenate, 2-4 parts of almond oil, 2.3-5 parts of bentonite, 3-7 parts of potassium dihydrogen phosphate, 1.5-2.8 parts of fatty alcohol polyethyleneoxy phosphate ester and 3.2-5.8 parts of nano vermiculite. Compared with the existing product, the environment-friendly floor adhesive disclosed by the invention is long in service life, high in strength after being dried and incapable of shrinking or cracking, has sound absorption and noise reduction functions and also has the characteristics of fire resistance, breathability, temperature regulation and humidity regulation; and the environment-friendly floor adhesive is high in performance cost ratio, and the market sale price of the environment-friendly floor adhesive is reduced by 30% than that of any other material by which the same ...

Fingerstall type force touch interaction device and interaction method applied to mobile terminal

The invention discloses a fingerstall type force touch interaction device applied to a mobile terminal. The fingerstall type force touch interaction device comprises a fingerstall assembly and the mobile terminal, wherein an insulating film and an electrostatic film are adhered on the surface of a touch screen; the fingerstall assembly comprises a control module, a conductive rubber sleeve, a force transducer and a piezoelectric transmitter, and the force transducer is fixedly connected with the upper surface of the piezoelectric transmitter; the control module comprises a touch device control unit, a power supply, a wireless communication module, a first touch driver and a second touch driver, the wireless communication module is connected with a serial port of the touch device control unit, a voltage output port of the first touch driver is connected with the piezoelectric transmitter, and a voltage output port of the second touch driver is connected with the electrostatic film. The fingerstall ...

Multifunctional hat

The invention discloses a multifunctional hat which comprises a hat body and a water drinking device. The hat comprises glasses holes and a lens adjusting device. The lens adjusting device is a strip-shaped cube, a shaft is arranged in the cube, and the surface of the shaft is provided with a thread-shaped groove. After the shaft penetrates the inside of the cube, one end of the shaft is fixedly connected with a knob, and the other end of the shaft is connected with a protruded block arranged on the side of the hat and provided with a thread through threads. The water drinking device comprises a water storage device, a water guiding pipe and a water drinking port. The water storage device is connected and communicated with the water guiding pipe located below the water storage device, the water guiding pipe is connected and communicated with the water drinking port located below the water guiding pipe, and an air discharging knob is arranged on the side of the water storage device. Various ...

Finish-milling machining method for two outer-circle end faces of automobile spring hanging ring

The invention discloses a finish-milling machining method for two outer-circle end faces of an automobile spring hanging ring. The method mainly comprises the following steps: (1) firstly, selecting a milling machine, and firstly milling from the center to the edges of two sides until the outer-circle end faces appear; (2) secondly, setting the feed amount of each tooth to 0.06mm/Z, setting the actual milling speed to 41.5m/min, and setting the feed amount of a workbench to 128mm/min; (3) finally, acquiring the machining time for milling one end face through the length L of a cut layer, which is 80mm and is obtained through a blank size, cutter cut length which is 40mm, and the number of cutter feeding times, which is 1, thereby obtaining the machining time of the working procedure, which is 1.6min. The method has the beneficial effects that by the method, the accuracy of workpiece machining can be ensured, favorable effects on machining quality, productivity and product cost caused by ...

Hop to hop transmission method based on satellite network

The invention discloses a hop to hop transmission method based on a satellite network, which belongs to the technical field of communication. The method comprises the following steps: arraying all data packets to be sent to a next hop in an array to send the data packets to a target node by a source node or a middle node; carrying out sequence confirmation on the data packets sent from the same sending node and returning confirmation information to a sending node of a previous hop by the middle node or the target node; judging whether the sent data packets are successfully sent or not by the sending node according to the returned confirmation information; if a data packet is not successfully sent, renewedly routing the data packet, and if the node of the next hop is changed, transferring the data packet to a corresponding array and renewedly numbering and sending the data packet. The method increases the information interactions of chain states, buffer memory spaces, and the like between ...

Power scheduling mains side data platform based on triple frameworks

The utility model discloses a power scheduling mains side data platform based on triple frameworks, including the CPU controller that adopts redundant configuration, the CPU controller is worked and is stood and the communication of data acquisition device with cloud ware, light cloud ware, independent server, operator respectively, independent server and the dispatcher control center working of enel station both -way communication, cloud ware and the workstation one -way communication of province warp letter committee, light cloud ware and province electric power research institute workstation one -way communication, all there is data sharing between independent server and light cloud ware and the cloud ware, acquire data among the data acquisition device follow generating set of power plant. The utility model discloses improve system security nature greatly, satisfied the requirement of the high reliability of high -speed collection of data and anecdotes.

Crane moving safety monitoring and management system based on mobile network

The invention belongs to the technical field of crane safety monitoring and management and particularly relates to a crane moving safety monitoring and management system based on a mobile network. The system comprises an information acquiring and transmitting unit, a remote information maintenance and management unit and a remote moving monitoring and controlling management unit; the information acquiring and transmitting unit transmits the crane safety monitoring data to the remote information maintenance and management unit through a 3G mobile network; the remote information maintenance and management unit receives the safety monitoring data through the 3G mobile network and stores into a central server for maintenance and management; the remote moving monitoring and controlling management unit selects the position and displaying manner of a monitoring sensor through remote mobile monitoring and controlling terminal equipment. By the aid of the 3G mobile network, the data transmitting ...

Positioning system based on multi-directional polarized light navigation sensor and positioning method of positioning system

The invention discloses a positioning system based on a multi-directional polarized light navigation sensor. The positioning system comprises a fixed frame and an upper computer, wherein polarized light angle sensors for measuring the maximum polarization direction of incident light are installed on any two planes respectively, a level sensor and a direction sensor are installed on a datum plane of the fixed frame, and an astronomical calendar query module and a geomagnetic information query module are arranged in the upper computer. According to the system, a polarized light navigation technology and astronomical knowledge are combined, measured values of the level sensor, the polarized light angle sensor and the direction sensor on the fixed frame are obtained, geomagnetic declination data information is queried through the geomagnetic information query module in the upper computer, sun declination delta values at certain moments and true sun time differences on certain days are queried ...

Keyword search rank determining method and device

An embodiment of the invention provides a keyword search rank determining method and device. The method comprises steps as follows: determining to-be-searched keywords; searching the keywords in a search engine to obtain search results corresponding to the keywords, wherein the search results comprise multiple search result pages; recording encrypted URLs (uniform resource locators) of all the search result pages in the search results and corresponding search result ranks; determining decrypted URLs corresponding to the encrypted URLs of all the search result pages; according to the decrypted URLs of all the search results, determining at least one platform decrypted URL with domain name information of network platforms in the decrypted URLs; according to the corresponding relation between preset platform decrypted URLs and platform user information, determining target platform users corresponding to all platform decrypted URLs; feeding back search result ranks corresponding to the corresponding ...

Environment-friendly sludge dewatering conditioner and application thereof

The invention relates to an environment-friendly sludge dewatering conditioner and an application thereof. The environment-friendly sludge dewatering conditioner comprises the following components in parts by weight: 0.4-1.2 parts of chitosan, 1-5 parts of trivalent ferric salt, 1-12 parts of modified attapulgite and 0.025-0.1 part of surfactant. The environment-friendly sludge dewatering conditioner is used for sludge dewatering. An application method of the environment-friendly sludge dewatering conditioner comprises the following steps: adding the surfactant accounting for 0.025%-0.1% of the dry weight of the sludge to be treated to the sludge to be treated under the conditions of ordinary temperature and pressure, and rapidly stirring for at least three minutes; afterwards, adding the modified attapulgite powder accounting for 1%-12% of the dry weight of the sludge to be treated and the trivalent ferric salt accounting for 1%-5% of the dry weight of the sludge to be treated, and rapidly ...

Rotary transformer initial position signal autocorrection method

The invention discloses a rotary transformer initial position signal autocorrection method, which realizes stator vector orientation through software, calculates the average value after multiple positions and multiple angles are tested. The method of the invention not only reduces the cost, but also improves the rotary transformer initial position signal autocorrection accuracy.

Device for eliminating ozone based on microwaves

The utility model provides a device for eliminating ozone based on microwaves, which relates to the technical field of ozone treatment and comprises a reaction cavity, a microwave source, a feeding hole, a gas inlet, a mixing cavity, a stirrer, a lamp tube, a bracket, a catalyst and a gas outlet, wherein the microwave source is arranged at the top of the reaction cavity; a lamp tube in the reaction cavity is fixed on the bracket; the stirrer is arranged in the mixing cavity; ozone enters the reaction cavity from the gas inlet, and the treated gas is discharged from the gas outlet under the action of a reducing agent, a microwave source and a lamp tube. Ozone and ozone are treated based on the action of microwaves, a reducing agent and an electrodeless ultraviolet lamp, efficient decomposition of ozone is achieved, and the device is simple in structure, low in energy consumption and capable of running stably for a long time.

Electric railway detection rail car

The utility model provides an electric railway detection rail car. The electric railway detection rail car comprises a car body, a workbench and a seat, a workbench is arranged on the front side of the top of the vehicle body, and a seat is fixed to the middle of the top of the vehicle body through bolts. A lithium battery is arranged at the bottom of the seat and fixed to the top of the vehicle body through bolts. A trapezoidal frame-shaped supporting frame is fixed to the rear side of the top of the vehicle body through bolts, and a motor is arranged at the bottom of the supporting frame; the multifunctional tea table has the advantages that the cup groove used for containing a cup is formed, so that the cup is not prone to toppling over, the storage rack is arranged below the table top,the space utilization rate below the table top is increased, the storage rack can be rotationally stored, use is flexible, and practicability is high, and therefore the problems and defects of the multifunctional ...

Water plan index verification method, device and system, and storage medium

The invention provides a water use plan index verification method, device and system, and a storage medium, and relates to the field of information processing. The water consumption plan index verification method comprises the following steps: inquiring whether a corresponding industry water consumption quota standard or an industry water consumption quota standard is published in the industry to which a water consumption unit belongs; and under the condition that the industry to which the water consumption unit belongs publishes the corresponding industry water consumption limit standard or the industry water consumption quota standard, determining the water consumption plan index of the water consumption unit by using the industry water consumption limit standard or the industry water consumption quota standard.

SNP (Single Nucleotide Polymorphism) molecular marker related to fear behavior and/or separation anxiety behavior of dog and application of SNP molecular marker

The invention provides an SNP molecular marker related to fear behavior and/or separation anxiety behavior of dogs and application thereof, and belongs to the technical field of molecular biology, the SNP molecular marker comprises a first molecular marker and/or a second molecular marker; the nucleotide sequence of the first molecular marker is shown as SEQ ID NO: 1, and the 34th site is a polymorphic site and has A/G polymorphism; the nucleotide sequence of the second molecular marker is as shown in SEQ ID NO: 2, and the 282 < th > site is a polymorphic site and has C/T polymorphism. The SNP molecular marker provided by the invention can be used for identifying the degree of fear behavior and/or anxiety separation behavior of dogs or breeding dogs with low or high degree of fear behavior and/or anxiety separation behavior, so that the time for breeding dogs is shortened, and the dog behavior judgment cost is reduced.

Asymmetric Gemini surfactant as well as preparation method and application thereof

The invention is applicable to the field of petroleum recovery, and provides an asymmetric Gemini surfactant as well as a preparation method and application thereof.The asymmetric Gemini surfactant provided by the invention has a lower critical micelle concentration, can form a micelle aggregate at a low concentration, and has the potential of micelle flooding or microemulsion flooding; compared with a single-chain surfactant with the same carbon chain length, the surfactant has higher capability of reducing surface tension and oil-water interfacial tension. Under the alkali-free or alkaline condition, the oil-water interfacial tension can be reduced, the oil displacement efficiency can be improved, and the method has great application potential in the field of chemical displacement for improving the recovery efficiency; the asymmetric Gemini surfactant has three charge sites, is good in solubility, can be combined with various counter ions, is strong in salt resistance, does not generate ...

Test tool, system and corresponding method for evaluating closing performance of hard small cigarette box

The invention discloses a test tool, a system and a corresponding method for evaluating the closing performance of a hard small cigarette case, the test tool comprises a case cover opening and closing angle stabilizing assembly, a cigarette packet fixing assembly and an opening and closing angle/height measuring assembly, the case cover opening and closing angle stabilizing assembly is arranged on the back of a cigarette case and is a right-angle slope inclining outwards, and the cigarette packet fixing assembly is arranged on the right-angle slope; after the box cover of the cigarette box is opened, the top of the box cover is in contact with the inclined surface; the cigarette packet fixing assembly is of a U-shaped double-right-angle structure, wraps the bottom and the two opposite side faces of the cigarette case and is used for fixing the cigarette case. The opening and closing angle/height measuring assembly is used for measuring the angle of a slit on the side face of the box cover ...

Removable circular assembled prefabricated open caisson and construction method

According to the removable circular assembled prefabricated open caisson and the construction method, the removable circular assembled prefabricated open caisson comprises a prefabricated shaft, the prefabricated shaft is formed by annularly splicing a plurality of longitudinally-arranged supporting columns, each supporting column comprises an overlapping part and a blade foot part, the overlapping part is formed by vertically connecting, installing and fixing a plurality of overlapping splicing blocks, and the blade foot parts are installed and fixed at the lower end of the overlapping part; at least one longitudinally-through grouting hole is formed in the middle of each overlapping splicing block, flow guide holes are formed in the inner side wall and the outer side wall of each overlapping splicing block respectively, and the flow guide holes are communicated with the grouting holes. Ground splicing, sinking through the open caisson method and pulling-out after backfilling in the prefabricated ...

Kluyveromyces lactis with weight-losing and lipid-lowering functions and application of Kluyveromyces lactis

The invention discloses Kluyveromyces lactis with weight-losing and lipid-lowering functions and application of the Kluyveromyces lactis, and belongs to the technical field of microorganisms. The Kluyveromyces lactis JSA18 is preserved in the China General Microbiological Culture Collection Center (CGMCC), the preservation number is CGMCC No.26714, and the preservation date is February 27, 2023. Kluyveromyces lactis JSA18 is utilized and used for maintaining a mouse with high fat diet, then liver and serum samples are obtained, and the body weight change and the level of total cholesterol TC and triglyceride TG are detected so as to evaluate the influence of the yeast on obesity and blood fat. Experiments show that the Kluyveromyces lactis JSA18 has good tolerance to environmental stress of gastrointestinal tracts in vivo. Results show that the Kluyveromyces lactis JSA18 can effectively reduce hyperlipidemia and fat accumulation caused by obesity, and a new treatment approach is provided ...

LOW SCALE POTENTIAL WATER TREATMENT

An electrochemical treating device having low scale potential is disclosed. The device has a variety of configurations directed to the layering of the anionic exchange and cationic exchange. The treatment device can also comprise unevenly sized ion exchange resin beads and/or have at least one compartment that provides a dominating resistance that results in a uniform current distribution throughout the apparatus. © KIPO & WIPO 2009 ...

Novel tricyclic compounds

The invention provides compounds of Formula (I) and Formula (II) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.

Rotor for brushless electric machine and brushless electric machine

A rotor for a brushless electric machine, having: a rotor core; a rotor shaft, installed inside the rotor core; multiple U-shaped holes are formed in the rotor core, each of the U-shaped holes including a first magnet installation hole, a second magnet installation hole and a hardening material filling hole formed by a bottom space of the U-shaped hole. A groove structure is formed on the rotor core forming a first surface of the hardening material filling hole, with the width of a groove opening of the groove structure being smaller than the width of the bottom of the groove. The rotor for a brushless electric machine provided in the present invention has the advantages of low internal magnetic circuit losses and a stable mechanical structure.

Method for efficiently preparing ferrate based on nascent interfacial activity

A method for efficiently preparing ferrate based on nascent state interfacial activity. The method is as follows: (a) preparing nascent iron solution; (b) adding an oxidizing agent to the iron solution of step (a); (c) adding alkali solution or alkali particles to the mixed solution of step (b), mixing by stirring, and carrying out solid-liquid separation; (d) adding a stabilizing agent to the liquid separated out in step (c), and thus obtaining ferrate solution. The yield is 78-98%. The prepared ferrate solution is stable and can be stored for 3-15 days.

A Drop-Resistant Contact Lenses Case

This invention discloses a drop-resistant contact lenses case, including a base 11. An adsorption device 100 is disposed in the base 11, and a case body 24 is disposed on an upper side of the base 11. A damping device 102 is disposed in the case body 24. The adsorption device 100 comprises a slider cavity 12 with a downward opening. The invention is simple in structure and convenient to operate; the device can be avoided from being touched to drop by adsorbing the suckers and the first torsional springs to the plane; and when the device drops, the vibration during the dropping are weakened through the second torsional springs and the springs, and the lenses are avoided from being damaged. 28u 25- -24 23- Hx,66" 21 11 12 13 18 17 19290 14 16 15 100 Figure I ...

N-halogenated amino acids and N, N-dihalogenated amino acids in combination with hypohalous acids

Self-hybridizing multiple target nucleic acid probes and methods of use

System and method for the prevention of bacterial and fungal infections including urinary tract infections (UTI) using N-halogenated amino acids

Multi-Metallic bulk catalyst with layered structure and method for the preparation and use thereof

The invention discloses a multi-metallic bulk catalyst with layered structure, wherein the metals in the multi-metallic bulk catalyst is consisted of a Group VIII metal M, at least one metal Mwith the valence of +3 and at least two Group VIB metals M+M, wherein (the mole number of M+the mole number of M):(the mole number of M+the mole number of M) is from 1:9 to 9:1; the mole number of M:the mole number of Mis from 1:5 to 5:1; and the mole number of M:the mole number of Mis from 1:5 to 5:1. The invention also discloses the preparation method and use of the above catalyst. The invention is use for the hydrodesulfurization of diesel distillate including 4,6-dimethyldibenzothiophene, wherein the catalyst exhibits a extreme high hydrodesulfurization activity. Thus, the ultra-deep hydrodesulfurization is achieved and the cost of the bulk catalyst is reduced. 1. A multi-metallic bulk catalyst with layered structure , wherein the metals in the multi-metallic bulk catalyst is consisted of a Group VIII metal M , at least one metal Mwith the valence of +3 and at least two Group VIB metals M+M , wherein{'sub': I', 'II', 'III', 'IV, '(the mole number of M+the mole number of M):(the mole number of M+the mole number of M) is from 1:9 to 9:1;'}{'sub': I', 'II, 'the mole number of M: the mole number of Mis from 1:5 to 5:1; and'}{'sub': III', 'D, 'the mole number of M: the mole number of M/is from 1:5 to 5:1.'}2. The multi-metallic bulk catalyst according to wherein Mis selected from Cr claim 1 , Al or Co; Mis selected from Ni; and one of Mand Mis Mo and the other is W.3. The multi-metallic bulk catalyst according to wherein (the mole number of M+the mole number of M):(the mole number of M+the mole number of M) is from 1:3 to 3:1; the mole number of M:the mole number of Mis from 1:2 to 2:1; the mole number of M: the mole number of Mis from 1:2 to 2:1.4. A process for preparing the multi-metallic bulk catalyst according to claim 1 , comprising the steps of:1) heating a solution of ...

METHOD OF SELECTING AN OPTIMAL VIEWING ANGLE POSITION FOR A CAMERA

This invention relates to a method of selecting an optimal viewing angle position for a camera. A first quantitative score is determined for a first viewing angle position of the camera using pre-selected regions of interest as reference areas, the determining being performed in accordance to a pre-defined quantitative score rule. The angle position is adjusted from the first viewing angle position towards at least one second viewing angle position. For each at least one second viewing angle position a second quantitative score is determined in accordance to the pre-defined quantitative score rule, and finally a target viewing angle position is determined based on the determined quantitative scores. 1. A method of selecting an optimal viewing angle position for a camera , comprising:{'b': 205', '206', '101, 'determining a first quantitative score for a first viewing angle position of the camera using pre-selected regions of interest (, ) as reference areas (), the determining being performed in accordance to a pre-defined quantitative score rule,'}{'b': '103', 'adjusting the angle position from the first viewing angle position towards at least one second viewing angle position (),'}{'b': '105', 'determining for each at least one second viewing angle position a second quantitative score () in accordance to said pre-defined quantitative score rule, and'}{'b': '107', 'determining a target viewing angle position () based on the determined quantitative scores.'}2205206301. A method according to claim 1 , wherein the pre-defined quantitative score rule includes determining whether there is an overlap amongst the regions of interest ( claim 1 , ) for the first and the at least one second viewing angle positions such that the more the overlap is between the regions of interest the lower will the quantitative score be claim 1 , and the larger the distance () is between the regions of interest the larger will the quantitative score be.3. A method according to claim 2 , ...

Semi-continuity fiber prepreg material, manufacturing method thereof, and composite material made of semi-continuity fiber prepreg material

The invention provides a semi-continuity fiber prepreg material, a manufacturing method thereof, and a composite material made of the semi-continuity fiber prepreg material. The semi-continuity fiber prepreg material includes a plurality of intermittency notches and/or continuity notches formed on a fiber prepreg material along at least one direction to make the fiber prepreg material soft and suitable for molding.

Parallel web page processing

Methods and systems for parallel Web page processing are usable to parallelize Web page document parsing, Web page layout calculations, Web page style formatting, and Web page script engine processing. Such parallelized parsers may be used to enhance Web page processing and exploit multi-core and multi-processor computing device resources. The parallelized script engine may be used to enhance Web page processing when independent scripting events exist in the Web page document. Additionally, the parallelized layout calculations and style formatting may be used to further enhance Web page processing by allowing multi-core and multi-processor computing devices to take advantage of their parallel processing abilities.

STYLE AND LAYOUT CACHING OF WEB CONTENT

Methods and systems for style and/or layout caching of Web content are usable to build reusable style caching trees and cacheable layout calculations. Such style caching trees may be used to avoid recalculating style content of Web pages for document object model (DOM) elements that have not changed. Additionally, the cacheable layout calculations may be used to avoid recalculating the layout content of Web pages that are subsequently accessed. 1. A computer-implemented method comprising: receiving a Web page file;', 'parsing the Web page file to create a document object model (DOM) tree comprising DOM tree nodes;', 'constructing a style caching tree comprising structure information of the DOM tree;', 'storing the style caching tree in a memory;', 'constructing a render tree comprising render objects based at least in part on the structure information of the DOM tree;', 'performing a layout calculation for render objects; and', 'storing the layout calculation results in the memory., 'performed by one or more processors executing computer-readable instructions2. The computer-implemented method of claim 1 , wherein the structure information comprises a parent node and/or a child node for each node in the style caching tree.3. The computer-implemented method of claim 1 , wherein constructing the style caching tree comprises:recursively parsing the DOM tree until each DOM tree node is represented by a corresponding style caching tree node; andmerging one or more corresponding style caching tree nodes that share a same parent node and a same selector of a selected set of cascading style sheet (CSS) rule selector types into a single merged style caching tree node.4. The computer-implemented method of claim 3 , wherein the selected set of CSS rule selector types comprises selectors of the type: identifier claim 3 , class claim 3 , or tag name.5. The computer-implemented method of claim 3 , wherein each style caching tree node comprises a matched CSS rule list and a style ...

Real-time self-calibrating sensor system and method

A system and method for calibrating a sensor of a characteristic monitoring system in real time utilizes a self-calibration module for periodic determination of, and compensation for, the IR drop across unwanted resistances in a cell. A current-interrupt switch is used to open the self-calibration module circuit and either measure the IR drop using a high-frequency (MHz) ADC module, or estimate it through linear regression of acquired samples of the voltage across the sensor's working and reference electrodes (Vmeasured) over time. The IR drop is then subtracted from the closed-circuit value of Vmeasured to calculate the overpotential that exists in the cell (Vimportant). Vimportant may be further optimized by subtracting the value of the open-circuit voltage (Voc) across the sensor's working and reference electrodes. The values of Vmeasured and Vimportant are then controlled by respective first and second control units to compensate for the IR drop.

Nanonized Iron Compositions and Methods of Use Thereof

Embodiments of the invention provide nanonized iron compositions for treatment of iron deficiency such as iron deficiency anemia. Many embodiments provide nanonized iron compositions which are sized to minimize adverse reaction such as immune response, adverse GI reaction and allergic reaction to iron compound included in the composition. The nanonized iron compositions can be used in a variety of drug delivery forms, including an oral dosage form, a transdermal patch, in an intravenous solution or in a dialysate for treatment of a patient with chronic kidney disease (CKD). Embodiments of the invention also provide methods of using the nanonized iron compositions for the treatment of iron deficiency in a patient in need thereof including patients with iron deficiency anemia and CKD. 1. A composition comprising nanoparticles of an iron-containing compound for the treatment of iron deficiency in a patient , the nanoparticles having a particle size or particle size range which minimizes an adverse reaction of a patient to administration of the iron-containing compound to increase an iron store in the patient.2. (canceled)3. (canceled)4. (canceled)5. (canceled)6. (canceled)7. (canceled)8. (canceled)9. (canceled)10. (canceled)11. (canceled)12. (canceled)13. (canceled)14. (canceled)15. (canceled)16. (canceled)17. (canceled)18. (canceled)19. (canceled)20. (canceled)21. (canceled)22. (canceled)23. (canceled)24. (canceled)25. (canceled)26. (canceled)27. (canceled)28. (canceled)29. (canceled)30. (canceled)31. (canceled)32. (canceled)33. (canceled)34. (canceled)35. (canceled)36. (canceled)37. (canceled)38. (canceled)39. (canceled)40. (canceled)41. (canceled)42. (canceled)43. (canceled)44. (canceled)45. (canceled)46. (canceled)47. (canceled)48. (canceled)49. (canceled)50. (canceled)51. (canceled)52. (canceled)53. A kit for administering nanoparticles of an iron-containing compound to a patient for the treatment of iron deficiency , the kit comprising:{'claim-ref': {'@idref': ' ...

CHILD CAR SEAT

A child car seat includes a seat member and a head rest device. The head rest device includes a main body and a top protection structure. The main body is connected to a top of the seat member. The top protection structure is located above the main body for protecting a top of a head of a child seated on the seat member. 1. A child car seat , comprising:a seat member; and a main body connected to a top of the seat member; and', 'a top protection structure located above the main body for protecting a top of a head of a child seating on the seat member., 'a head rest device, comprising2. The child car seat of claim 1 , wherein the top protection structure protrudes forwardly from the main body claim 1 , so as to be located above the head of the child.3. The child car seat of claim 2 , further comprising:a lateral protection structure protruding forwardly from both sides of the main body, and the main body, the top protection structure and the lateral protection portion cooperatively forming a containing space for containing the head of the child.4. The child car seat of claim 3 , wherein the main body claim 3 , the top protection portion and the lateral protection portion are connected to one another claim 3 , so as to form the containing space.5. The child car seat of claim 3 , wherein the lateral protection structure and the top protection structure are integrally formed.6. The child car seat of claim 3 , wherein the top protection structure is connected to the lateral protection structure in a screwing claim 3 , wedging or tight fit manner.7. The child car seat of claim 3 , wherein the lateral protection structure and the top protection structure are made of shock absorption material claim 3 , respectively.8. The child car seat of claim 1 , wherein the head rest device is disposed on the seat member in a slidable manner.9. The child car seat of claim 8 , further comprising:a first sliding structure disposed on a side of the seat member; anda second sliding ...

System and Method for The Prevention of Bacterial and Fungal Infections Including Urinary Tract Infections (UTI) Using N-Halogenated Amino Acids

Disclosed is a system that prevents the development of infection and biofilm establishment in medical devices in general, and in particular Urinary Tract Infections (UTI), including Catheter-Associated Urinary Tract Infections (CAUTI). The system comprises a medical device (such as a catheter) and an antimicrobial composition containing an antimicrobial compound. A medical device delivers the composition both to the inside and/or outside portions of the device, as well as to the inside of the bladder itself and to the urethra. Reduction or elimination of the infection may be accomplished by irrigating the medical device, bathing the bladder, or irrigating the bladder with the composition. 172.-. (canceled)73. An aqueous antimicrobial composition for the treatment or prevention of a microbial infection in a patient , the composition comprising(a) an antimicrobially effective amount of at least one N-halogenated amino acid, an N-halogenated amino acid derivative or an N-halogenated amino acid source;(b) at least one halide salt selected from the group consisting of sodium chloride, sodium bromide, potassium chloride, potassium bromide, magnesium chloride, magnesium bromide and mixtures thereof; the halide salt concentration is from 0 to about 20 g/L of the aqueous composition;(c) a pH of about 2 to about 8; and(d) a constituent selected from the group consisting of calcium and magnesium chelating agents, biologically acceptable acids and/or salts thereof that are compatible with the antimicrobial composition, and mixtures thereof to maintain the pH at the range between about 2 and 8; and optionally(e) an antimicrobially effective amount of HOBr or HOCl, or a source or composition capable of releasing HOBr or HOCl.74. The composition of claim 73 , wherein the biologically acceptable acid is citric acid and the biologically acceptable salt is potassium citrate.75. The composition of claim 73 , wherein the chelating agent is malic acid or maltol claim 73 , and the ...

DEVELOPMENT AND EVALUATION OF NOVEL CHINESE MATERIA MEDICA PREPARATIONS

Nuclear receptor LXR is an important member of 49 nuclear receptors in human bodies and has irreplaceable regulatory effects on cholesterol and fat metabolisms. The regulation of the biological activity of LXR may have therapeutic effects to the conditions such as cardiovascular and cerebrovascular obstructions, non-insulin dependent hyperglycemia, immune function disorders, and central nerve functional degeneration. We have developed a group of novel Chinese materia medica preparations targeting nuclear receptor LXR by using a computer-simulated docking technology and a process for determining biological activities of human cells cultured ex vivo. The group of preparations are featured by simple ingredients, low costs, easy to prepare, etc. No significant adverse effects were found in initial acute toxicology analysis which was carried out using mice. 1. Use of ex-vivo cultured human cells in detecting the biological transcription activities of a nuclear receptor , liver X receptor (LXR) , so as to determine pharmacodynamic effects of Chinese materia medica preparations.2. A process for preparing derivatives of natural triterpenes extract with an aqueous solution comprising sodium hydroxide , ethanol , and hydrogen peroxide , so as to improve the pharmaceutical values of Chinese materia medica preparations.3. The process of claim 2 , wherein the content of sodium hydroxide in the aqueous solution is in the range of 1-20% claim 2 , the content of ethanol is in the range of 10-80% claim 2 , and the content of hydrogen peroxide is the range of 1-10%.4. The process of claim 3 , wherein the content of sodium hydroxide in the aqueous solution is 4% claim 3 , the content of ethanol is 50% claim 3 , and the content of hydrogen peroxide is 4%.5. The process of claim 1 , wherein the content of the triterpenes extract is consistent with the corresponding content of sodium hydroxide.6GynostemmaHedysari. The process of claim 5 , wherein the triterpenes compounds comprise Radix ...

REAL-TIME SELF-CALIBRATING SENSOR SYSTEM AND METHOD

A system and method for calibrating a sensor of a characteristic monitoring system in real time utilizes a self-calibration module for periodic determination of, and compensation for, the IR drop across unwanted resistances in a cell. A current-interrupt switch is used to open the self-calibration module circuit and either measure the IR drop using a high-frequency (MHz) ADC module, or estimate it through linear regression of acquired samples of the voltage across the sensor's working and reference electrodes (Vmeasured) over time. The IR drop is then subtracted from the closed-circuit value of Vmeasured to calculate the overpotential that exists in the cell (Vimportant). Vimportant may be further optimized by subtracting the value of the open-circuit voltage (Voc) across the sensor's working and reference electrodes. The values of Vmeasured and Vimportant are then controlled by respective first and second control units to compensate for the IR drop. 1. A system for calibrating a sensor of a characteristic monitoring system in real time by determining , and compensating for , an IR drop across unwanted resistances in a cell , said sensor including a counter electrode , a reference electrode , and a working electrode in communication with a user's blood or interstitial fluids to produce signals indicative of said characteristic , the system comprising:a first control unit having a potentiostat, said potentiostat including an operational amplifier connected in an electrical circuit to maintain substantial equality between the magnitude of a measured voltage across the sensor's working and reference electrodes and the magnitude of an applied voltage;a current-interrupt switch electrically connected between the operational amplifier's output and the sensor's counter electrode to provide a closed circuit when the switch is closed and an open circuit when the switch is opened; and ["wherein the second control unit estimates the magnitude of the IR drop through linear ...

Novel Tricyclic Compounds

The invention provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.

SYSTEM AND METHOD FOR BIPHASIC TRANSDERMAL IONTOPHREOTIC DELIVERY OF THERAPEUTIC AGENTS

Various embodiments provide methods and systems for the biphasic iontophoretic transdermal delivery of therapeutic agents. An embodiment of a method for such delivery comprises positioning at least one electrode assembly in electrical communication with a patient's skin. The assembly includes a solution comprising a therapeutic agent which passively diffuses into the skin. A dose of agent is delivered from the assembly into the skin during a first period using a first current having a characteristic e.g., polarity and magnitude, to repel the agent out of the assembly. During a second period, a second current having a characteristic to attract the agent is used to retain the agent in the assembly such that delivery of agent into skin is minimized. A dose of agent may be delivered on demand by an input from the patient. Embodiments may be used for delivery of agents which cause adverse effects from unwanted passive diffusion. 1. A method for transdermal delivery of a therapeutic agent to a patient by iontophoresis , the method comprising:positioning at least one electrode assembly in electrical communication with the skin of the patient, the at least one electrode assembly including a skin contacting layer and a solution comprising the therapeutic agent, wherein the therapeutic agent passively diffuses into the skin without application of an external force;delivering a dose of therapeutic agent from the at least one electrode assembly into the skin during a first period using a first current having a polarity and magnitude to repel the therapeutic agent out of the electrode assembly;retaining the therapeutic agent in the at least one electrode assembly during a second period using a second current having a polarity and magnitude to retain the therapeutic agent in the electrode assembly such that delivery of the therapeutic agent into the skin during the second period is minimized, wherein the first period comprises a delivery period and the second period comprises a ...

Novel tricyclic compounds

The invention provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.

LOW SCALE POTENTIAL WATER TREATMENT

An electrochemical treating device having low scale potential is disclosed. The device has a variety of configurations directed to the layering of the anionic exchange and cationic exchange. The treatment device can also comprise unevenly sized ion exchange resin beads and/or have at least one compartment that provides a dominating resistance that results in a uniform current distribution throughout the apparatus. 164-. (canceled)65. An electrodeionization apparatus comprising:a depleting compartment having a first depleting layer of a first ion exchange media and a second depleting layer of a second ion exchange media positioned above the first depleting layer to form a depleting layer interface at a first level; anda concentrating compartment in ionic communication with and adjacent the depleting compartment and defined by an anion selective membrane and a cation selective membrane, the concentrating compartment having a first concentrating layer of a third ion exchange media and a second concentrating layer of a fourth ion exchange media positioned above the first concentrating layer to form a concentrating layer interface at a second level that is different from the first level.66. The apparatus of claim 65 , wherein the first ion exchange media is a mixture of anion exchange media and cation exchange media.67. The apparatus of claim 66 , wherein the second ion exchange media is anion exchange media.68. The apparatus of claim 67 , wherein the third ion exchange media is a mixture of anion exchange media and cation exchange media.69. The apparatus of claim 68 , wherein the fourth ion exchange media is anion exchange media.70. The apparatus of claim 67 , wherein the first concentrating layer of the third ion exchange media includes a first zone comprised of cation exchange media that is separated from the anion selective membrane by a second zone comprised of anion exchange media.71. The apparatus of claim 70 , wherein the fourth ion exchange media is anion ...

NOVEL TRICYCLIC COMPOUNDS

The invention provides compounds of Formula (I) and Formula (II) 3. The compound of wherein Ris -A-D-E-G and D is an optionally substituted (C-C)alkylene claim 1 , optionally substituted (C-C)cycloalkylene claim 1 , optionally substituted bridged (C-C)cycloalkenylene claim 1 , optionally substituted (C-C)bridged heterocyclylene or optionally substituted (C-C)heterocyclylene.4. The compound of wherein D is optionally substituted (C-C)alkylene claim 3 , optionally substituted (C-C)cycloalkylene claim 3 , optionally substituted bicyclo[2.2.2]octany-1-yl claim 3 , optionally substituted 2 claim 3 ,5-diazabicyclo[2.2.1]heptane claim 3 , optionally substituted 2 claim 3 ,6-diazabicyclo[3.2.1]octane claim 3 , optionally substituted octahydropyrrolo[3 claim 3 ,4-c]pyrrole claim 3 , optionally substituted octahydropyrrolo[3 claim 3 ,2-b]pyridine claim 3 , optionally substituted 1 claim 3 ,4-diazepane claim 3 , optionally substituted cubane claim 3 , optionally substituted 1 claim 3 ,4-dioxane-spiro[4.4]nonane claim 3 , optionally substituted 2 claim 3 ,5-diazaspiro[3.5]nonane claim 3 , optionally substituted piperidine claim 3 , optionally substituted piperazine claim 3 , optionally substituted pyrrolidine claim 3 , optionally substituted tetrahydrofuran or optionally substituted tetrahydropyran.6. The compound of wherein Ris -A-D-E-G and G is hydrogen claim 1 , deuterium claim 1 , —N(R)(R) claim 1 , halogen claim 1 , —OR claim 1 , —S(O)R claim 1 , —CN claim 1 , —C(O)N(R)(R) claim 1 , —N(R)C(O)R claim 1 , —CF claim 1 , —S(O)N(R)(R) claim 1 , an optionally substituted —(C-C)alkyl claim 1 , an optionally substituted —(C-C)cycloalkyl claim 1 , an optionally substituted —(C-C)heteroaryl claim 1 , an optionally substituted —(C-C) heterocyclyl claim 1 , or an optionally substituted —(C-C)aryl;{'sup': a', 'b', 'a', 'b', 'a', 'b, 'sub': 2', '10', '1', '10, 'wherein in a moiety containing —N(R)(R), the nitrogen, Rand Rmay form a ring such that —N(R)(R) represents an optionally ...

SILICA CRUCIBLE AND METHOD FOR FABRICATING THE SAME

A silica crucible and a fabricating method thereof are provided. The silica crucible includes a vitreous silica body having an inner surface and an outer surface, the inner surface of the vitreous silica body defining a cavity adapted for containing a molten material or a powder material; and a first coating layer formed on the inner surface of the vitreous silica body. The first coating layer is formed by pyrolysing a composite of aluminum, magnesium, calcium, titanium, zirconium, radium, chromium, selenium, barium, yttrium, cerium, hafnium, tantalum, tin or silicon under a predetermined temperature. The first coating layer substantially includes of a nonhomogeneous material, and an interface is defined by the homogeneous material and the nonhomogeneous material between the vitreous silica body and the coating layer. The first coating layer has strong adhesion capability and guarantees the coating layer will not be easily peeled off or removed. 1. A silica crucible , comprising:a vitreous silica body having an inner surface and an outer surface, the inner surface of the vitreous silica body defining a cavity adapted for containing at least one of a molten material or a powder material; anda first coating layer formed on the inner surface of the vitreous silica body;wherein the first coating layer is formed by pyrolysing a composite of at least one of aluminum, magnesium, calcium, titanium, zirconium, radium, chromium, selenium, barium, yttrium, cerium, hafnium, tantalum, tin or silicon under a predetermined temperature; andwherein the first coating layer substantially comprises a nonhomogeneous material, and an interface is defined by a homogeneous material and the nonhomogeneous material between the vitreous silica body and the coating layer.2. The silica crucible of claim 1 , wherein when forming the first coating layer claim 1 , the predetermined temperature of the vitreous silica body is maintained between about 650° C. and about 1600° C.3. The silica crucible ...

TEMPORALLY CONSISTENT DEPTH ESTIMATION FROM BINOCULAR VIDEOS

The present invention relates to method and apparatus for temporally-consistent depth estimation. Such a depth estimation preserve both object boundary as well as temporal consistency using techniques of segmentation and pixel trajectory. 1. A method for generating temporally-consistent depth map by one or more processors receiving a sequence of images , comprising:receiving one first pair of images in the sequence of images of time instance t and at least one second pair of images in the sequence of images from other time instances t+i wherein each pair of images being different views of the same scene;generating a segmentation map of a third image by clustering a plurality of pixels in the image into a plurality of image regions, wherein the third image being one of the first pair of images;generating a long-range pixel trajectory of the third image by identifying a correspondence between each pixel in the third image and each pixel in one of the second pair of images;generating a temporally-consistent edge map of the third image by determining the probability of each pixel in the third image being an object boundary using the segmentation map and the long-range pixel trajectory;generating an edge-refined depth map for the first pair of images using the temporally-consistent edge map such that probability of each pixel in the third image being a depth discontinuity is determined based on probability of the pixel being on an object boundary; andgenerating a temporally-consistent depth map for the first pair of images from the edge-refined depth map using the long-range pixel trajectory to adjust depth of each pixel in the third image according to optical flow of the pixel in at least one image in the sequence of images at other time instances.2. The method of claim 1 , further comprising:concatenating a plurality of short-range optical flow maps for the generation of the long-range pixel trajectory.3. The method of claim 2 , further comprising:processing the ...

APPARATUS, SYSTEM, AND METHOD FOR TEMPORAL DOMAIN HOLE FILLING BASED ON BACKGROUND MODELING FOR VIEW SYNTHESIS

Embodiments of apparatuses, systems, and methods for a temporal hole filling are described. Specifically, an embodiment of the present invention may include a depth-based hole filling process that includes a background modeling technique (SGM). Beneficially, in such an embodiment, holes in the synthesized view may be filled effectively and efficiently. 1. A method for temporal domain hole filling based on background modeling for view synthesis comprising:receiving texture information associated with a plurality of pixels in a video frame;receiving depth information associated with the plurality of pixels in the video frame;determining whether an update to a background model associated with the video frame is required in response to the texture information and the depth information associated with each of the plurality of pixels in the video frame; andupdating the background model in response to the texture information and the depth information.2. The method of claim 1 , further comprising initiating a new background model in response to a determination that a background model does not exist for a pixel in the plurality of pixels.3. The method of claim 1 , wherein information from the background model for each of the plurality of pixels in the video frame is used to fill holes caused by a disocclusion of the video frame.4. The method of claim 1 , wherein updating the background model comprises refining a pixel in the background model in response to the texture information and the depth information.5. The method of claim 1 , further comprising storing the pixel in a buffer in response to a determination that a difference in depth between the current pixel and a corresponding pixel in the background model exceeds a threshold value.6. The method of claim 1 , wherein updating the background model comprises replacing the background model with a new background model in response to a determination that a difference between the current pixel and a corresponding pixel in the ...

Method for Efficiently Preparing Ferrate Based on Nascent Interfacial Activity

A method for efficiently preparing ferrate based on nascent state interfacial activity. The method is as follows: (a) preparing nascent iron solution; (b) adding an oxidizing agent to the iron solution of step (a); (c) adding alkali solution or alkali particles to the mixed solution of step (b), mixing by stirring, and carrying out solid-liquid separation; (d) adding a stabilizing agent to the liquid separated out in step (c), and thus obtaining ferrate solution. The yield is 78-98%. The prepared ferrate solution is stable and can be stored for 3-15 days. 1: A high efficiency preparation method for ferrate based on activity in nascent state interface , characterized in that , the high efficiency preparation method for ferrate based on activity in nascent state interface comprises the steps of:(a) adding iron salt to a first alkaline solution with a pH of 5˜9 for hydrolysis and producing an iron solution in nascent state with an equivalent concentration of iron of 0.0001˜1 mol/L;(b) measuring and obtaining 5˜100 mL of the iron solution in nascent state obtained from step (a), adding oxidizing agent based on a molar ratio of the iron in nascent state and the oxidizing agent at 1:0.1˜20, and allowing to mix to obtain a mixture;(c) under the condition of 5° C.˜60° C., adding 5˜100 mL the second alkaline solution with a concentration of 0.1˜16 mol/L or adding 0.2˜70 g alkaline granules to the mixture obtained from the step (b); stirring and mixing for 0.1˜30 min; allowing the solution to turn purplish black color completely and then process solid-liquid separation by centrifugation or filtration to obtain a liquid; and(d) adding stabilizing agent based on a molar ratio of the equivalent concentration of iron in the liquid obtained from the step (c) and the stabilizing agent of 1:0.1˜10 to obtain a ferrate solution.2: The high efficiency preparation method for ferrate based on activity in nascent state interface according to claim 1 , characterized in that claim 1 , in ...

PRIMARY CARBOXAMIDES AS BTK INHIBITORS

The invention provides compounds of Formula (I) 2. The compound according to claim 1 , wherein Y is CRand Rof Y is H claim 1 , optionally substituted ethenyl claim 1 , optionally substituted ethyl claim 1 , optionally substituted methyl claim 1 , optionally substituted 2 claim 1 ,3-dihydrobenzofuranyl claim 1 , optionally substituted 1 claim 1 ,4-dioxanyl claim 1 , optionally substituted 3 claim 1 ,4-dihydro-2H-benzo[b.][1 claim 1 ,4]oxazinyl claim 1 , optionally substituted 6 claim 1 ,7-dihydro-4H-pyrazolo[5 claim 1 ,1-c][1 claim 1 ,4]oxazinyl claim 1 , optionally substituted chromanyl claim 1 , optionally substituted cyclohexenyl claim 1 , optionally substituted cyclopropyl claim 1 , optionally substituted tetrahydrofuranyl claim 1 , optionally substituted isochromanyl claim 1 , optionally substituted 1 claim 1 ,2 claim 1 ,3 claim 1 ,4-tetrahydro-isoquinolinyl claim 1 , optionally substituted isoxazolyl claim 1 , optionally substituted morpholinyl claim 1 , optionally substituted oxetanyl claim 1 , optionally substituted phenyl claim 1 , optionally substituted piperidinyl claim 1 , optionally substituted piperazinyl claim 1 , optionally substituted 3 claim 1 ,6-dihydro-2H-pyranyl claim 1 , optionally substituted pyrano[4 claim 1 ,3-b]pyridinyl claim 1 , optionally substituted pyrazolyl claim 1 , optionally substituted pyridinyl claim 1 , optionally substituted 3H-pyridin-1-one claim 1 , optionally substituted 1 claim 1 ,2 claim 1 ,3 claim 1 ,6-tetrahydropyridinyl claim 1 , optionally substituted pyrimidinyl claim 1 , optionally substituted pyrrolidinyl claim 1 , optionally substituted 2 claim 1 ,5-dihydropyrrolyl claim 1 , optionally substituted tetrahydropyranyl or optionally substituted tetrahydro-2H-thiopyranyl.3. The compound according to wherein Ris H or Ris optionally substituted by one or more substituents independently selected from the group consisting of CN claim 2 , OH claim 2 , ═O claim 2 , halogen claim 2 , (C-C)alkyl claim 2 , (C-C)alkoxy claim 2 , — ...

GENERATING WEBSITES AND BUSINESS DOCUMENTS FROM SEED INPUT

A method for generating a website includes obtaining a seed input associated with an entity. The seed input may include one or more keywords, such as a business name. Obtaining the seed input may include receiving the seed input from the user, or the seed input may be obtained without input from the user. The method further includes retrieving, using at least one of the seed input and the identification of the entity, content relevant to the entity from one or more data stores. The method may include generating an online store from product information within the retrieved content. The method may include identifying data elements from the retrieved content to be included in business documents, and generating the business documents. 1. A method , comprising:obtaining, by a server computer communicatively coupled to an electronic network, a seed input, the seed input comprising one or more URLs;accessing, by the server computer, a website at one of the URLs;identifying, by the server computer, one or more target data elements within the website;presenting, by the server computer, the one or more target data elements to a user for approval; andgenerating, by the server computer, one or more business document templates containing the target data elements.2. The method of claim 1 , wherein identifying the one or more target data elements within the website comprises:attempting to identify a builder of the website, the builder using a known identifier for one or more of the target data elements; andupon determining the identity of the builder, using the known identifier to locate the target data element and extract the target data element.3. The method of claim 1 , wherein identifying the one or more target data elements within the website comprises:parsing each cascading style sheet (CSS) for the website to obtain a background image URL for each background image referenced in the CSSs; andevaluating each of the background image URLs for the presence of one or more ...

COMMUNICATIONS CONTROL METHOD, COMMUNICATIONS TERMINAL, AND STORAGE MEDIUM

This application discloses a communications control method and a communications terminal, so as to implement a change between a point-to-point chat and a group chat among multiple persons, and a user may set a chat identity of the user by using a character. The communications control method provided in this application includes: controlling, by a communications terminal, a first character to move on a character layer, and displaying, on a communications display interface of the communications terminal, different characters on the character layer with the movement of the first character, the first character being displayed on the communications display interface of the communications terminal, the character layer including: the first character and at least one character other than the first character, and the first character being a user object that represents a user when the user chats using the communications terminal; obtaining, by the communications terminal, chat content entered by the user into the communications terminal; and displaying, by the communications terminal, the chat content on the communications display interface as an identity of the first character. 1. A communications control method performed at a first communications terminal having one or more processors and memory storing one or more programs to be executed by the one or more processors , wherein the first communications terminal is one of a group of communications terminals communicatively coupled to one another in support of a group chat among users of the group of communications terminals , the method comprising:displaying a graphical user interface corresponding to the group chat, the graphical user interface including a first set of characters, each character representing a user of a respective communications terminal;detecting a first message from a user of the first communications terminal through the graphical user interface;in response to the first message, transmitting the first ...

THERAPEUTIC TARGETING OF SET1B/COMPASS PATHWAY FOR TREATING CANCERS

Disclosed are methods for treating Set1/COMPASS-associated cancers characterized by expression of Set1B/COMPASS. The methods typically include administering a therapeutic amount of an inhibitor of the Set1B/COMPASS pathway and/or an agonist for a target that is negatively regulated by the Set1B/COMPASS pathway. 1. A method for treating a cancer characterized by expression of Set1B/COMPASS in a subject in need thereof , the method comprising administering to the subject a therapeutic amount of an inhibitor of Set1B/COMPASS and/or administering an agonist of a target that is negatively regulated by Set1B/COMPASS.2. The method of claim 1 , wherein the cancer is breast cancer.3. The method of claim 1 , wherein the cancer is ER-negative breast cancer.4. The method of claim 1 , wherein the cancer is HERB2-negative breast cancer.5. The method of claim 1 , wherein the cancer is PR-negative breast cancer.6. The method of claim 1 , wherein the cancer is triple negative breast cancer (TNBC).7. The method of comprising administering to the subject an agonist of the of adiponectin receptor 1.9. The method of comprising administering to the subject a therapeutic agents selected from the group consisting of a peptide mimetic of adiponectin claim 1 , matairesinol claim 1 , arctiin claim 1 , (−)-arctigenin claim 1 , gramine claim 1 , and 6-C-beta-D-glcypyranosyl-(2S claim 1 ,3S)-(+)-5 claim 1 ,7 claim 1 ,3′ claim 1 ,4′-tetrahydroxydihydroflavonol (GTDF).10. The method of comprising administering to the subject RNA interference (RNAi) therapy and inhibiting expression of Set1B/COMPASS.11. A method comprising identifying a cancer subject that has one or more mutations in a gene of the Set1/COMPASS pathway and/or identifying a cancer subject that is overexpressing Set1/COMPASS claim 1 , and administering to the subject a therapeutic amount of an inhibitor of Set1B/COMPASS and/or administering an agonist of a target that is negatively regulated by Set1B/COMPASS.12. The method of claim ...

TRANSFER APPARATUS AND LASER ANNEALING APPARATUS

A transfer apparatus includes a supporting member, a free electron excitation device and a detection device; the free electrons excitation device is configured to excite semiconductor material of an object to be transferred to generate free electrons, and the detection device is configured to detect whether material of a surface of the transferred object in contact with the support surface of the supporting member is conductive under excitation by the free electron excitation device. A laser annealing apparatus comprising the transfer apparatus is further provided. 1. A transfer apparatus , comprising:a supporting member,a free electron excitation device, configured to excite a semiconductor material of an transferred object to generate free electrons; anda detection device, configured to detect whether a surface of the transferred object in contact with a support surface of the supporting member becomes conductive or not.2. The transfer apparatus according to claim 1 , wherein the free electron excitation device is a heat excitation device claim 1 , a light excitation device claim 1 , or an electromagnetic field excitation device.3. The transfer apparatus according to claim 2 , wherein the electromagnetic field excitation device comprises an electromagnet attached to the supporting member.4. The transfer apparatus according to claim 3 , wherein the electromagnetic field excitation device further comprises a power supply device claim 3 , the electromagnet comprises a coil that comprises two terminals claim 3 , and the power supply is connected with the two terminals of the coil of the electromagnet and is configured to supply power to the coil.5. The transfer apparatus according to claim 3 , wherein the detection device comprises:at least two electrodes, which are attached to the support surface of the supporting member and are configured to be in contact with a surface of the transferred object in operation;a voltage source, which is connected with the at least two ...

Photodetectors based on interband transition in quantum wells

The present application relates to a photodetector based on interband transition in quantum wells. The photodetector may include a first semiconductor layer having a first conduction type; a second semiconductor layer having a second conduction type different from the first conduction type; and a photon absorption layer arranged between the first semiconductor layer and the second semiconductor layer, the photon absorption layer including at least one quantum well layer and barrier layers arranged on both sides of each quantum well layer. The present application utilizes the modulating effect of a semiconductor PN junction on a photoelectric conversion process associated with quantum wells to significantly increase a current output of the photodetector based on the quantum well material.

RADIOPROTECTIVE NANODRUG FOR SMALL INTESTINE AND PREPARATION METHOD THEREOF

The present invention relates to a method for constructing a nanodrug with adhesion in small intestine, including activating a basic amino acid with a small molecular catalyst, adding a polysaccharide solution and reacting to obtain an amphiphilic polymer; then adding a drug solution and mixing uniformly, to obtain drug-loaded nanoparticles including a hydrophilic portion that is the basic amino acid and a hydrophobic portion that is the polysaccharide and drug, wherein the drug has radioprotective effect or can inhibit ionizing radiation-induced cell death; and adding the drug-loaded nanoparticles to a dopamine solution to obtain a nanodrug including the basic amino acid and polydopamine on the surface after the reaction. The present invention provides an oral nanodrug with adhesion in intestinal tract, and the nanodrug has good biocompatibility, adhesion in small intestine and mucus barrier penetration ability, and can withstand the acid and alkali environment in the gastrointestinal tract. 1. A method for preparing a nanodrug for small intestine , comprising the following steps:(1) activating a hydrophilic basic amino acid with a small-molecule catalyst in an acidic buffer solution, then adding a polysaccharide solution, mixing uniformly and reacting at pH 4.5-5.5 and 20-30° C. to obtain an amphiphilic high-molecular polymer; then adding a drug solution and mixing uniformly, to obtain drug-loaded nanoparticles comprising a hydrophilic portion that is the basic amino acid and a hydrophobic portion that is the polysaccharide and drug, wherein the drug has radiation protection effect or has the effect of inhibiting ionizing radiation-induced cell death, and the drug is positively charged in agastricacid environment; and(2) adding the drug-loaded nanoparticles obtained in Step (1) to a dopamine solution, and reacting at pH 8.0-10.0 and 25-50° C., to obtain a nanodrug having a surface modified with polydopamine after the reaction is complete.2. The preparation method ...

VACUUM ADSORBING WORKBENCH AND VACUUM ADSORBING DEVICE

A vacuum adsorbing workbench and a vacuum adsorbing device are provided. The vacuum adsorbing workbench includes a workbench body, a first suction tube and an occluder. The workbench body is provided with multiple suction holes. Each suction hole is in communication with the first suction tube. The occluder is able to be connected with the first suction tube cooperatively to cut off communication between each suction hole and the first suction tube. 1. A vacuum adsorbing workbench , comprising a workbench body , a first suction tube and an occluder , wherein the workbench body is provided with a plurality of suction holes; andwherein each of the plurality of suction holes is in communication with the first suction tube, and the occluder is configured to be connected with the first suction tube cooperatively to cut off communication between each of the plurality of suction holes and the first suction tube.2. The vacuum adsorbing workbench according to claim 1 , wherein the plurality of suction holes is arranged in an array claim 1 , the suction holes in a same row are in communication with each other via the first suction tube claim 1 , and the suction holes in different rows are not in communication with each other;wherein a quantity of the first suction tube and a quantity of the occluder are both plural, each of the quantity of the plurality of the first suction tubes and the quantity of the plurality of the occluders is the same as a quantity of rows of the suction holes, and each of the first suction tubes is in communication with a corresponding row of suction holes and is not in communication with the suction holes in other rows; andwherein the plurality of occluders is configured to be cooperatively connected with the plurality of first suction tubes respectively.3. The vacuum adsorbing workbench according to claim 2 , wherein each of the plurality of first suction tubes is provided with a plurality of air inlets at a tube wall of the first suction tube claim ...

GLUCOCORTICOID RECEPTOR AGONIST AND IMMUNOCONJUGATES THEREOF

Provided herein are glucocorticoid receptor agonist immunoconjugates, glucocorticoid receptor agonists, and methods of using the same. 3. The antibody drug conjugate of claim 2 , wherein n is 1 claim 2 , 2 claim 2 , 3 claim 2 , 4 claim 2 , 5 claim 2 , 6 claim 2 , 7 claim 2 , 8 claim 2 , 9 claim 2 , or 10.4. The antibody drug conjugate of claim 2 , wherein n is 4.5. The antibody drug conjugate of claim 2 , wherein n is 2.6. A pharmaceutical composition comprising the antibody drug conjugate of and a pharmaceutically acceptable carrier.7. A method of treating a condition selected from rheumatoid arthritis claim 4 , ankylosing spondylitis claim 4 , psoriatic arthritis claim 4 , plaque psoriasis claim 4 , ulcerative colitis claim 4 , adult Crohn's disease claim 4 , pediatric Crohn's disease claim 4 , uveitis claim 4 , hidradenitis suppurativa claim 4 , and juvenile idiopathic arthritis in a subject claim 4 , comprising administering an effective amount of the antibody drug conjugate of to the subject.8. A kit comprising:{'claim-ref': [{'@idref': 'CLM-00004', 'claim 4'}, {'@idref': 'CLM-00006', 'claim 6'}], '(a) a container comprising the antibody drug conjugate of or the pharmaceutical composition of ; and'}(b) a label or package insert on or associated with the one or more containers, wherein the label or package insert indicates that the antibody drug conjugate or pharmaceutical composition is used for treating a condition selected from rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, plaque psoriasis, ulcerative colitis, adult Crohn's disease, pediatric Crohn's disease, uveitis, hidradenitis suppurativa, and juvenile idiopathic arthritis.9. A method of delivering a glucocorticoid receptor agonist to a TNFα-expressing cell claim 4 , comprising the step of contacting the cell with the antibody drug conjugate of . This application claims priority to U.S. Provisional Application No. 62/593,776, filed Dec. 1, 2017 and U.S. Provisional Application No. 62/ ...

Estimation of NOx Generation in A Commercial Pulverized Coal Burner using a Dynamic Chemical Reactor Network Model

NOx generation in a coal burning furnace is estimating using a chemical reactor network model. The model is constructed with ideal chemical reactor modules, an input matrix and a tunable parameter matrix defining split ratios and flow rates among the ideal chemical reactor modules. Values in the tunable parameter matrix are learned by first measuring actual furnace outputs of the coal burning furnace for a known set of actual furnace inputs, and then applying the chemical reactor network, including an initially populated tunable parameter matrix, to a populated input matrix representing the known set of actual furnace inputs. The actual furnace outputs are compared with the output matrix, and the tunable parameter matrix is adjusted based on the comparison. 1. A method for estimating NOx generation in a coal burning furnace , comprising:measuring actual furnace outputs of the coal burning furnace, including NOx generation, for a known set of actual furnace inputs; a plurality of ideal reactor modules;', 'an input matrix defining chemical reactor network inputs; and', 'a tunable parameter matrix defining split ratios and flow rates among the plurality of ideal reactor modules;, 'constructing a chemical reactor network comprisingapplying the chemical reactor network, including an initially populated tunable parameter matrix, to a populated input matrix representing the known set of actual furnace inputs, to create an output matrix including an estimate of NOx generation;making a comparison of the actual furnace outputs with the output matrix;based on the comparison, creating an adjusted tunable parameter matrix.2. The method of claim 1 , wherein the chemical reactor network inputs include concentrations of compositions in coal.3. The method of claim 1 , wherein the chemical reactor network inputs include input air temperature and flow rate.4. The method of claim 1 , wherein the output matrix further includes volumetric flow rate and temperature.5. The method of claim ...

AFFINITY CHROMATOGRAPHY WASH BUFFER

A wash buffer comprising greater than 0 mM and less than about 500 mM arginine, greater than 0 mM and less than about 250 mM guanidine, greater than 0 mM and less than about 250 mM sodium chloride, and greater than 0 mM and less than about 50 mM of an anionic surfactant, or greater than 0% and less than about 0.25% w/v of a non-ionic surfactant. When used during affinity chromatography purification of a protein of interest, such as an antibody, the wash buffer significantly reduces the level of host cell proteins from the preparation. Following affinity chromatography with the wash buffer, the protein of interest may be further purified using membrane chromatography. 1. An affinity chromatography wash solution , comprising water , a basic amino acid , and guanidine.2. The wash solution according to claim 1 , wherein the basic amino acid is arginine.314-. (canceled)15. The wash solution of claim 1 , wherein the solution further comprises an anionic surfactant.1619-. (canceled)20. The wash solution of claim 1 , wherein the anionic surfactant comprises sodium octanoate.21. The wash solution of claim 1 , wherein the solution further comprises sodium chloride.2226-. (canceled)27. The wash solution of claim 1 , wherein the solution comprises a pH of about 7.5.28. A composition claim 1 , comprising an aqueous carrier claim 1 , a recombinantly-expressed or hybridoma-expressed antibody that specifically binds to:(a) TNF-like ligand 1A (TL1a), and a level of host cell proteins from about 50 ppm to about 500 ppm of the composition,(b) calcitonin gene-related peptide (CGRP), and a level of host cell proteins at a level of from about 400 ppm to about 800 ppm of the composition, or(c) CD38, and a level of host cell proteins at a level of from about 50 ppm to about 500 ppm of the composition.2933-. (canceled)34. The composition of claim 28 , wherein the antibody comprises:(a) a VH comprising the amino acid sequence of SEQ ID NO: 5 and a VL comprising the amino acid sequence of SEQ ...

TOUCH DISPLAY PANEL AND MANUFACTURING METHOD THEREOF

Disclosed are a touch display panel and a manufacturing method thereof, the touch display panel includes an array substrate and an opposed substrate disposed oppositely; a set of first electrode lines parallel to each other disposed on the array substrate or the opposed substrate; a set of second electrode lines parallel to each other disposed on the array substrate or the opposed substrate and arranged to cross the first electrode lines. The first electrode lines and the second electrode lines have no electrical connection therebetween, and the array substrate or the opposed substrate comprises a black matrix; the first electrode lines and/or the second electrode lines correspond to positions of the black matrix and the first electrode lines and/or the second electrode lines corresponding to positions of the black matrix are metal electrode lines. 1. A touch display panel , comprising:an array substrate and an opposed substrate disposed oppositely to each other;a set of first electrode lines parallel to each other disposed on the array substrate or the opposed substrate; anda set of second electrode lines parallel to each other disposed on the array substrate or the opposed substrate and arranged to cross the first electrode lines;wherein the first electrode lines and the second electrode lines have no electrical connection therebetween, and the array substrate or the opposed substrate comprises a black matrix; the first electrode lines and/or the second electrode lines correspond to positions of the black matrix, and the first electrode lines and/or the second electrode lines corresponding to the positions of the black matrix are metal electrode lines.2. The touch display panel of claim 1 , wherein the first electrode lines and the second electrode lines both correspond to the positions of the black matrix;the first electrode lines and the second electrode lines both are metal electrode lines.3. The touch display panel of claim 1 , wherein the first electrode ...

SALT-ISOLATED RAIN GARDEN STRUCTURE

The present invention belongs to the technical field of landscape garden engineering, and specifically discloses a salt-isolated rain garden structure. The salt-isolated rain garden structure includes a depression surrounded by side slopes, where a 10 cm thick drainage layer, a 10-30 cm thick filler layer, a 5 cm thick transition layer, a 20-30 cm thick planting layer, a 0.2-0.5 cm thick mulch layer and a 15-20 cm thick ponding layer are stacked in order from the bottom of the depression to up; a salt barrier is disposed between the planting layer and the transition layer and/or between the drainage layer and a saline layer; a vertical overflow pipe and a horizontal drainage pipe are disposed at the bottom of the depression; the overflow pipe and drainage pipe are connected; the salt barrier is filled with river sand, zeolite or ceramsite and is 10-20 cm in thickness. 1. A salt-isolated rain garden structure , comprising a depression surrounded by side slopes , wherein a 10 cm thick drainage layer , a 10-30 cm thick filler layer , a 5 cm thick transition layer , a 20-30 cm thick planting layer , a 0.2-0.5 cm thick mulch layer and a 15-20 cm thick ponding layer are stacked in order from the bottom of the depression to up; a salt barrier is disposed between the planting layer and the transition layer and/or between the drainage layer and a saline layer; a vertical overflow pipe and a horizontal drainage pipe are disposed at the bottom of the depression; the overflow pipe and drainage pipe are connected; the salt barrier is filled with river sand , zeolite or ceramsite and is 10-20 cm in thickness.2. The salt-isolated rain garden structure according to claim 1 , wherein the particle size of the river sand is 0.25-0.35 mm; the particle size of the zeolite is 2-4 mm; and the particle size of the ceramsite is 10-25 mm.3. The salt-isolated rain garden structure according to claim 1 , wherein the drainage layer is filled with gravel with a diameter of 10-20 mm.4. The salt- ...

SYSTEM AND METHODS FOR MONITORING DEFECATION, URINATION, NEAR-BODY TEMPERATURE, BODY POSTURE AND BODY MOVEMENTS IN YOUNG CHILDREN, PATIENTS AND ELDERLIES

Remotely detecting the presence of urine or feces in a diaper of an infant or adult using a disposable sensor placed inside the diaper, in conjunction with a permanent device that is capable of wirelessly transmitting data to a mobile device or base station is disclosed. The permanent device can also be capable of measuring temperature and body movements. This additional information can be used in conjunction with the detection of urine or feces to identify patterns. 1. A system for detecting waste material comprising:one or more sensors configured to change one or more parameters in the presence of the waste material, anda first device communicatively coupled to the one or more sensors and configured for receiving first data from the one or more sensors associated with the change in the one or more parameters and transmitting second data associated with the first data;wherein the second data is indicative of detected waste material.2. The system of claim 1 , wherein the one or more sensors comprise at least two layers claim 1 , with a plurality of electrodes formed on one of the at least two layers.3. The system of claim 1 , wherein the one or more sensors comprise at least two layers claim 1 , with a plurality of electrodes formed on different ones of the at least two layers and staggered so as to not rest upon each other.4. The system of claim 1 , wherein the one or more sensors include a plurality of electrodes formed with apertures to allow liquid or other substances to pass through.5. The system of claim 1 , wherein the first device includes at least one of a motion sensing mechanism and a temperature sensing mechanism claim 1 , and the second data includes at least one of motion data and temperature data.6. A system of claim 5 , further comprising a second device for receiving the second data from the first device and generating a notification based on the second data.7. The system of claim 6 , wherein at least one of the first and second devices includes at ...

Method for preparing high-valence iron salt

A method for preparing high-valence iron salt; the present invention relates to a method for preparing a ferrate compound, for solving the technical problems of the complex operating process, the low yield, and the low purity of ferrate products after purification in existing methods for preparing potassium ferrate. The preparation method comprises: 1. weighing solid potassium hydroxide; 2. adding the solid potassium hydroxide to a sodium hypochlorite solution to obtain a hypochlorite solution; 3. adding iron salt to the hypochlorite solution to obtain a potassium ferrate solution; 4. adding the potassium ferrate solution to a cooled potassium hydroxide solution to obtain a solid-liquid mixture; 5. filtering the solid-liquid mixture of step 4; and 6. rinsing the solid-phase substance. The present invention has safe operation, is simple, quick, energy-saving, and easy to control, is suitable for immediate use, and the obtained product can be stored stably; the ferrate yield of the present method is 60-95% and the purity of the produced potassium ferrate solid is over 95%.

PROCESS MODEL REPAIRING METHOD BASED ON STRUCTURE REPLACEMENT

The present disclosure provides a process model repairing method based on structure replacement. Firstly, two ordering relationship sets of an event log and a model are obtained by re-defining ordering relationships between activities, and a deviation set recording differences between the event log and the model is obtained; next, the model is repaired according to the deviation set. A selective structure or a sequential structure is changed into a concurrent structure according to the given event log in the present disclosure. The repaired model indicated by a logical Petri net is capable of accurately reflecting a logical relationship between activities. The method of the present disclosure and other model repairing methods are compared through simulation experiments. Experimental results show that a process model repaired by the method of the present disclosure has higher precision, correctly reflects an actual business process, and improves an execution efficiency of the business process, and the model indicated by the logical Petri net has better simplicity. 1at step I, obtaining two ordering relationship sets of an event log and a model by re-defining ordering relationships between activities, and obtaining a deviation set recording differences between the event log and the model,wherein a business process changes along with a change of an actual situation; at this time, it is required to perform conformance checking for an original process model and an event log generated by an actual business process;when the process model is not conformant with the event log, a deviation is discovered;a method of collecting all deviations between an event log and a process model based on an extended ordering relationship is proposed below;to accurately identify some relationships between activities in the event log, the following concepts are proposed:defining the extended ordering relationship:{'img': [{'@id': 'CUSTOM-CHARACTER-00018', '@he': '3.22mm', '@wi': '3.22mm', '@ ...

System and method for image reconstruction

The present disclosure relates to a system and method for generating an image. At least one processor, when executing instructions, may perform one or more of the following operations. When raw data relating to an object is retrieved, an image may be generated based thereon. A first voxel of the image is identified based a first geometric parameter relating to the first voxel; a second voxel of the image is identified based on a second geometric parameter relating to the second voxel; the image is reconstructed using an iterative reconstruction process, during which the calculation relating to the first voxel is based on the first number of sub-voxels, and the calculation relating to the second voxel is based on the second voxel.

Medical Image Segmentation Based on Mixed Context CNN Model

An image volume formed by plural anatomical images each having plural image slices of different imaging modalities is segmented by a 2D convolutional neural network (CNN). An individual anatomical image is preprocessed to form a mixed-context image by incorporating selected image slices from two adjacent anatomical images without any estimated image slice. The 2D CNN utilizes side information on multi-modal context and 3D spatial context to enhance segmentation accuracy while avoiding segmentation performance degradation due to artifacts in the estimated image slice. The 2D CNN is realized by a BASKET-NET model having plural levels from a highest level to a lowest level. The number of channels in most multi-channel feature maps of a level decreases monotonically from the highest level to the lowest level, allowing the highest level to be rich in low-level feature details for assisting finer segmentation of the individual anatomical image. 1. A computer-implemented method for segmenting an image volume formed by a plurality of anatomical images imaged at a sequence of successive locations of a body part , an individual anatomical image being a multi-channel image comprising a plurality of image slices imaged at a same location under a plurality of preselected imaging modalities , the method comprising:generating a plurality of mixed-context images from the plurality of anatomical images, wherein an individual mixed-context image generated for a considered location in the location sequence other than two terminal locations thereof is a multi-channel image comprising the plurality of image slices of a corresponding anatomical image imaged at the considered location, a first set of one or more image slices imaged at a first location, and a second set of one or more image slices imaged at a second location, and wherein the first and second locations are immediately before and immediately after the considered location in the location sequence, respectively, avoiding the ...

TRANSPORTERS OF OIL SENSORS FOR DOWNHOLE HYDROCARBON DETECTION

Various embodiments of the present disclosure pertain to nanocomposites for detecting hydrocarbons in a geological structure. In some embodiments, the nanocomposites include: a core particle; a polymer associated with the core particle; a sulfur-based moiety associated with the polymer; and a releasable probe molecule associated with the core particle, where the releasable probe molecule is releasable from the core particle upon exposure to hydrocarbons. Additional embodiments of the present disclosure pertain to methods of detecting hydrocarbons in a geological structure by utilizing the nanocomposites of the present disclosure. 1. A nanocomposite suitable for detecting hydrocarbons in a geological structure , wherein the nanocomposite comprises:a core particle;a polymer associated with the core particle;a sulfur-based moiety associated with the polymer; anda releasable probe molecule associated with the core particle,wherein the releasable probe molecule is releasable from the core particle upon exposure to hydrocarbons, wherein the releasable probe molecule is triheptylamine (“THA”).2. The nanocomposite of claim 1 , wherein the core particle is selected from the group consisting of carbon black claim 1 , functionalized carbon black claim 1 , oxidized carbon black claim 1 , carboxyl functionalized carbon black claim 1 , carbon nanotubes claim 1 , functionalized carbon nanotubes claim 1 , graphenes claim 1 , graphene oxides claim 1 , graphene nanoribbons claim 1 , graphene oxide nanoribbons claim 1 , metal nanoparticles claim 1 , silica nanoparticles claim 1 , silicon nanoparticles claim 1 , silicon oxide nanoparticles claim 1 , silicon nanoparticles bearing a surface oxide claim 1 , and combinations thereof.3. (canceled)4. (canceled)5. (canceled)6. (canceled)7. (canceled)8. (canceled)9. (canceled)10. (canceled)11. (canceled)12. (canceled)13. (canceled)14. (canceled)15. The nanocomposite of claim 1 , wherein the sulfur-based moiety is a sulfate moiety with the ...

CATION EXCHANGE CHROMATOGRAPHY WASH BUFFER

A wash buffer comprising a surfactant for use in affinity and cation exchange chromatography to purify proteins of interest from protein aggregates and to remove and/or inactivate viruses. When used during affinity or cation exchange chromatography for the purification of a protein of interest, such as an antibody, the wash buffer significantly improves viral clearance from the preparation, while also reducing the levels of host cell proteins and protein aggregates. Following affinity or cation exchange chromatography with the wash buffer, the protein of interest may be further purified using other chromatography and filtration operations. 1. A method of purifying a protein of interest bound to a cation exchange (CEX) chromatography support comprising applying a wash solution comprising one or more surfactants to the CEX chromatography support.2. (canceled)3. The method of claim 1 , comprising loading a mixture comprising a protein of interest and one or more contaminant proteins claim 1 , aggregates claim 1 , and/or viruses onto the CEX chromatography support before applying the wash solution comprising one or more surfactants to the CEX chromatography support claim 1 , and then eluting the protein of interest from the support claim 1 , thereby forming a purified eluate of the protein of interest.4. A method for purifying a protein of interest claim 1 , comprising loading a mixture comprising a protein of interest and one or more contaminant proteins claim 1 , aggregates claim 1 , and/or viruses onto a CEX chromatography support claim 1 , washing the support with an aqueous wash solution comprising one or more surfactants to elute the one or more contaminant proteins claim 1 , aggregates claim 1 , and/or viruses from the support claim 1 , and then eluting the protein of interest from the support claim 1 , thereby forming a purified eluate of the protein of interest.5. The method of claim 3 , wherein one or more surfactants comprises Lauryldimethylamine N-oxide ( ...

CURABLE THERMOSETTING RESIN COMPOSITION

The present invention relates to a curable thermosetting resin composition including a multicomponent copolymer of monomers represented by general formulas (I), (II), (III) and (IV), an epoxy resin, a curing agent, etc. In the present invention, the phosphorus element is creatively introduced into a ternary or quaternary copolymer that is capable of undergoing a cross-linking reaction with an epoxy resin, and the ternary or quaternary copolymer is mixed with the epoxy resin and the like to form a composition meeting all the requirements that the cured product has a high glass transition temperature, a low dielectric constant and dielectric loss factor, and a certain flame resistance. The multicomponent copolymer is prepared through two methods, in which one method includes direct copolymerization of corresponding monomers and the other method includes initial copolymerization with a hydroxyl-containing monomer and the following esterification with phosphoric acid. 2. The curable thermosetting resin composition according to claim 1 , wherein in the multicomponent copolymer claim 1 , the structural unit (I) accounts for 0.1-60 wt % of the copolymer claim 1 , a molar ratio of the structural unit (II) to the structural unit (III) is 1:1-20:1 claim 1 , and the structural unit (IV) accounts for 0-60 wt % of the copolymer.3. The curable thermosetting resin composition according to claim 1 , wherein the multicomponent copolymer is curable together with the epoxy resin.4. The curable thermosetting resin composition according to claim 1 , wherein the weight ratio of the multicomponent copolymer to the epoxy resin in the composition is 5-100:100.5. The curable thermosetting resin composition according to claim 1 , wherein the cured product of the curable thermosetting resin composition has a glass transition temperature of at least 120° C. claim 1 , and at a frequency of 1 GHZ or higher claim 1 , the curable thermosetting resin composition has a dielectric constant of 3.1 or ...

PRIMERS, METHODS AND KITS FOR DETECTING KILLER-CELL IMMUNOGLOBULIN-LIKE RECEPTOR ALLELES

Embodiments of the present invention describe primer pairs, methods and kits for identifying and/or detecting killer-cell immunoglobulin-like receptor (KIR) alleles. The present primer sets include one or more primer pairs that can produce amplicons specific for an individual KIR allele and that are less than 1000 bp in size. Additionally, the primer sets can target intra-exon and/or extracellular domains of KIR alleles for amplification. 1. A primer set for identifying a killer-cellimmunoglobulin-like receptor (KIR) allele, comprising:a first primer pair that comprises a first primer and second primer capable of producing an amplicon that is less than or 1000 bases in length from an intra-exon portion of a nucleic acid that encodes for an extracellular portion of a KIR.2. The primer set of claim 1 , further comprising:one or more additional primer pairs that comprise a first primer and second primer capable of producing an amplicon that is less than or 1000 bases in length from an intra-exon portion of a nucleic acid that encodes for an extracellular portion of one or more additional KIRs.3. The primer set of wherein the primer set comprises primer pairs that are capable of identifying all presently known KIRs.4. The primer set of wherein a majority of the primer pairs comprise primers that are capable of producing an amplicon that is less than or 1000 bases in length from an intra-exon portion of a nucleic acid that encodes for an extracellular portion of the KIR.5. A primer set for identifying all of the presently known KIR alleles comprising:a plurality of primer pairs that are capable of identifying all presently known KIR alleles, wherein a majority of the primer pairs are capable of producing an amplicon that is less than or 1000 bases in length from a nucleic acid that encodes a KIR.6. The primer set of wherein one or more of the primer pairs of the majority of the primer pairs are capable of producing an amplicon that is less than or 1000 bases in length ...

BONDING DEVICE FOR CHIP ON FILM AND DISPLAY PANEL AND BONDING METHOD FOR THE SAME

The embodiments of the present disclosure provide a bonding device for a chip on film and a display panel and a bonding method for the same. The bonding device includes: a bearing stage having a horizontal bearing surface for supporting at least one row of display panels, wherein one row of the at least one row of display panels has a row of first bonding regions; a grasping unit disposed above the bearing stage and configured to grasp at least a partial area of the entire chip on film so that a row of second bonding regions of the entire chip on film is horizontally located above the one row of display panels; and a bonding unit configured to bond the row of second bonding regions which has been aligned with the row of first bonding regions to the row of first bonding regions. 1. A bonding device for a chip on film and a display panel , comprising:a bearing stage having a horizontal bearing surface for supporting at least one row of display panels, wherein one row of the at least one row of display panels has a row of first bonding regions;a grasping unit disposed above the bearing stage and configured to grasp at least a partial area of the entire chip on film so that a row of second bonding regions of the entire chip on film is horizontally located above the one row of the display panels; anda bonding unit configured to bond the row of second bonding regions which has been aligned with the row of first bonding regions, to the row of first bonding regions.2. The bonding device according to claim 1 , further comprising a driving unit configured to enable the grasping unit and the bearing stage to move with respect to each other so that the row of second bonding regions is aligned with the row of first bonding regions.3. The bonding device according to claim 2 , further comprising a controller connected to the driving unit in a signal transmittable manner.4. The bonding device according to claim 3 , further comprising a detection unit connected to the controller in ...

Acquiring cervical images

The invention provides a system ( 100 ) for acquiring cervical images which comprises an image acquisition subsystem ( 120 ) for acquiring cervical images ( 122 ) of a cervical region of a patient during a colposcopy procedure, and a display subsystem ( 160 ) for displaying the cervical images on a display ( 060 ) by providing image data ( 162 ) of the cervical images to the display. According to the invention, the image acquisition subsystem ( 120 ) is arranged for, when operating in an interval mode, acquiring the cervical images ( 122 ) at predetermined time intervals to obtain a time-series of cervical images showing changes in the cervical region over time, and reporting a progress of said acquiring to the display subsystem. Moreover, the display subsystem ( 160 ) is arranged for establishing a progress indicator ( 400 - 416 ) on the display by generating indicator data ( 164 ) and providing the indicator data to the display ( 060 ), the progress indicator providing visual feedback on the progress of said acquiring to a user. Accordingly, the user is provided with visual feedback on a status of the acquiring of the cervical images. In particular, the progress indicator avoids that the user experiences a loss of control or confusion.

THERAPEUTIC TARGETING OF THE BAP1 COMPLEX IN CANCER

Disclosed are methods for methods, compounds, and compositions for treating cancers characterized by therapeutic targeting of the BAP1 histone H2A deubiquitinase (DUB) complex, otherwise referred to herein as the BAP1 complex. In particular, the methods, compounds, and compositions disclosed herein relate to the use of therapeutic agents that inhibit the biological activity of the BAP1 complex for treating cancers such as myeloid neoplasms. 1. A method for treating cancer in a subject in need thereof , the method comprising administering to the subject a therapeutic amount of a therapeutic agent that inhibits the biological activity of the BAP1 histone H2A deubiquitinase (DUB) complex (BAP1 complex).2. The method of claim 1 , wherein the cancer is a myeloid neoplasm.3. The method of claim 1 , wherein the cancer is selected from the group consisting of acute myeloid leukemia (AML) claim 1 , myelodysplastic syndrome (MDS) claim 1 , myeloproliferative neoplasm (MPN) claim 1 , chronic myelomonocytic leukemia (CMML) claim 1 , and chronic myeloid leukemia (CML).4. The method of claim 1 , wherein the subject has a mutation in the ASXL1 gene.5. The method of claim 1 , wherein the subject has a mutation in the ASXL1 gene that results in a truncated ASXL1 protein. This application claims the benefit of priority under 35 U.S.C. § 119(e) to U.S. Provisional Application 62/875,434, filed on Jul. 17, 2019, the content of which is incorporated herein by reference in its entirety.This invention was made with government support under CA197569 awarded by the National Institutes of Health. The government has certain rights in the invention.The content of the ASCII text file of the sequence listing named “702581_01800_ST25.txt” which is 1.94 kb in size was created on Nov. 10, 2020 and electronically submitted via EFS-Web herewith the application is incorporated herein by reference in its entirety.The field of the invention relates to methods for treating cancers. In particular, the ...

ESTIMATION OF PERIPHERAL VASCULAR RESISTANCE USING A MINIATURE PIEZOELECTRIC SENSOR

A wearable assembly has a pulse plethysmography (PPG) sensor and a piezoelectric pressure sensor and is attachable to a patient's finger or other area corresponding to a peripheralvascular region, and further includes a signal processor configured to monitor blood flow dependent measurements and pressure measurements over time, comparing these measurements to determine properties of the vascular region, such as vascular resistance of a blood vessel, vascular radius of the blood vessel, vascular stiffness of the vascular region, blood pressure, and/or cardiac vascular power. The signal processor may apply a hysteresis comparison of the sensor outputs, e.g., using an elliptical model, and in some examples may apply an extended Kalman filter for optimizing output of the vascular region properties. 1. An apparatus comprising: a piezoelectric pressure sensor configured to measure pressure data of the peripheral vascular region, wherein the piezoelectric sensor comprises a piezoelectric electrode structure positioned to measure the pressure data in response to movement of a blood vessel in the peripheral vascular region, and', 'a pulse-oximetry sensor positioned to collect photoplethysmograph derived blood flow data of the blood vessel; and, 'a wearable sensor assembly configured to be attached to a subject at a peripheral vascular region, the wearable sensor assembly comprising receive the pressure data from the piezoelectric pressure sensor,', 'analyze the pressure data and output a pressure value,', 'analyze the collected photoplethysmograph derived blood flow and output a photoplethysmograph blood flow value, using a blood flow model,', 'compare the photoplethysmograph blood flow value with the pressure value, using a hysteresis comparison, and', 'in response to the comparison, extract an indicator of peripheral vascular resistance of the blood vessel, wherein the indicator of peripheral vascular resistance indicates vascular health and condition of the subject., 'a ...

NOVEL TRICYCLIC COMPOUNDS

The invention provides compounds of Formula (I) and Formula (II) 2. The compound of wherein Ris -A-D-E-G and A is a bond claim 1 , optionally substituted (C-C)alkylene claim 1 , optionally substituted (C-C)cycloalkylene or optionally substituted (C-C)heterocyclylene.3. The compound of wherein Ris -A-D-E-G and D is an optionally substituted (C-C)alkylene claim 1 , optionally substituted (C-C)cycloalkylene claim 1 , optionally substituted bridged (C-C)cycloalkenylene claim 1 , optionally substituted (C-C) bridged heterocyclylene or optionally substituted (C-C)heterocyclylene.4. The compound of wherein D is optionally substituted (C-C)alkylene claim 3 , optionally substituted (C-C)cycloalkylene claim 3 , optionally substituted bicyclo[2.2.2]octany-1-yl claim 3 , optionally substituted 2 claim 3 ,5-diazabicyclo[2.2.1]heptane claim 3 , optionally substituted 2 claim 3 ,6-diazabicyclo[3.2.1]octane claim 3 , optionally substituted octahydropyrrolo[3 claim 3 ,4-c]pyrrole claim 3 , optionally substituted octahydropyrrolo[3 claim 3 ,2-b]pyridine claim 3 , optionally substituted 1 claim 3 ,4-diazepane claim 3 , optionally substituted cubane claim 3 , optionally substituted 1 claim 3 ,4-dioxane-spiro[4.4]nonane claim 3 , optionally substituted 2 claim 3 ,5-diazaspiro[3.5]nonane claim 3 , optionally substituted piperidine claim 3 , optionally substituted piperazine claim 3 , optionally substituted pyrrolidine claim 3 , optionally substituted tetrahydrofuran or optionally substituted tetrahydropyran.6. The compound of wherein Ris -A-D-E-G and G is hydrogen claim 1 , deuterium claim 1 , —N(R)(R) claim 1 , halogen claim 1 , —OR claim 1 , —S(O)R claim 1 , —CN claim 1 , —C(O)N(R)(R) claim 1 , —N(R)C(O)R claim 1 , —CF claim 1 , —S(O)N(R)(R) claim 1 , an optionally substituted —(C-C)alkyl claim 1 , an optionally substituted —(C-C)cycloalkyl claim 1 , an optionally substituted —(C-C)heteroaryl claim 1 , an optionally substituted —(C-C) heterocyclyl claim 1 , or an optionally substituted ...

3D BRAIDED COMPOSITED TUBES WITH THROAT SECTIONS AND MANUFACTURE METHOD THEREOF

A manufacture method of a three dimensional (3D) braided composite tube with a throat section includes: providing an assembled mandrel comprising an upper mandrel and a lower mandrel, and braiding an 3D braided inner layer on the upper mandrel; winding fiber yarns to form a fiber yarn layer over the 3D braided inner layer; tightening the 3D braided inner layer to the assembled mandrel by an appropriate tension force when winding; and infiltrating resin and increasing temperature to cure the resin for obtaining a composite tube with a narrower throat section. The present invention takes advantage of winding fiber yarn outer layer to keep the radius of the throat of the 3D braided inner layer to meet design requirement. Additionally, the hoop strength of the throat section is increased so that the metal shell can be made thinner to reduce the weight of the rocket nozzle. 1. A three dimensional (3D) braided composite tube with a throat section , comprising:a 3D braided inner layer; anda fiber yarn outer layer, wound over the 3D braided inner layer;wherein the throat section is located at the middle portion of the 3D braided composite tube.2. The 3D braided composite tube of claim 1 , wherein the 3D braided composite tube with a throat section further comprises:a convergent section, coupled to one end of the throat section; anda divergent section, couple to the other end of the throat section.3. The 3D braided composite tube of claim 1 , wherein the convergent section allows the 3D braided composite tube to converge toward the throat section claim 1 , and the divergent section allows the throat section diverge toward the 3D braided composite tube.4. The 3D braided composite tube of claim 1 , wherein the 3D braided inner layer has a pre-tension force.5. The 3D braided composite tube of claim 1 , wherein the fiber yarn outer layer has a pre-tension force.6. The 3D braided composite tube of claim 1 , wherein the material of the 3D braided inner layer comprises carbon fiber ...

MOBILE NETWORKING METHOD AND SYSTEM FOR MINIMIZING INTERFERENCE

The invention provides a mobile networking method and system for minimizing interference. The mobile networking method comprises the following steps: unmanned aerial vehicles establish connection and communication with ground base stations through a wireless relay method; connection and communication between the unmanned aerial vehicles are established through a wireless self-networking method; multiple unmanned aerial vehicles cooperate to form a cellular network to provide wireless network services for users; the unmanned aerial vehicles receive a received signal strength indicator fed back by user equipment and measure the angle of arrival of a signal beam from the user equipment; the main lobe of a signal is made to aim at the direction of arrival of service users and the null is made to aim at the direction of arrival of interference signals through a mobile interference alignment method and a beam forming method, and thus the optimal hovering position is searched out. The invention has the following beneficial effects: interference between adjacent cells is reduced through the mobility of the unmanned aerial vehicle sub-base stations, and existing wireless network equipment is mainly adopted and no professional equipment is needed, so that the method and system have extremely high universality. 1. A mobile networking method for minimizing interference , comprising the following steps:S1: unmanned aerial vehicles establish connection and communication with ground base stations through a wireless relay method;S2: connection and communication between the unmanned aerial vehicles are established through a wireless self-networking method;53: multiple unmanned aerial vehicles cooperate to form a cellular network to provide wireless network services for users;S4: the unmanned aerial vehicles receive a received signal strength indicator fed back by user equipment and measure the angle of arrival of a signal beam from the user equipment;S5: the unmanned aerial vehicles ...

INDOOR POSITIONING METHOD AND SYSTEM BASED ON WIRELESS RECEIVER AND CAMERA

The invention provides an indoor positioning method and system based on a wireless receiver and a camera, belonging to the field of positioning technology. The method in the invention comprises the following steps: a wireless receiver detects a query WIFI signal transmitted by a target device and extracts a MAC address and CSI of the target device from a query WIFI signal; a server captures the MAC address and the CSI of the target device from the wireless receiver, calculates an incident angle of the target device and the wireless receiver and sends a photographing instruction to a camera which photographs an image and uploads the image to the server; the server obtains the distance between the wireless receiver and the target device through the image pixels, and calculates the position information of the target device according to the coordinates of the wireless receiver. The invention realizes the accurate positioning of the target device by using only a wireless receiver and a camera, so that the cost can be controlled and a real-time calculation can be ensured; the combination of the two beneficial effects can help achieve good positioning results. 1. An indoor positioning method based on a wireless receiver and a camera , comprising the following steps:{'b': '1', 'S: the wireless receiver detects a query WIFI signal transmitted by a target device;'}{'b': '2', 'S: the wireless receiver extracts a media access control (MAC) address and channel state information (CSI) used for identifying the target device from a query WIFI signal, and uploads the CSI to a server;'}{'b': '3', 'S: the server calculates an incident angle of the target device and the wireless receiver according to the CSI uploaded by the wireless receiver, and at the same time sends a photographing instruction to the camera which photographs an image and uploads the image to the server;'}{'b': '4', 'S: the server obtains a distance between the wireless receiver and the target device through the ...

WATERPROOF AND ELECTRICITY-INSULATING SUPPORT STRUCTURE FOR SOLAR PANELS

A waterproof and electricity-insulating support structure for solar panels includes a base frame having a top portion with two side portions disposed at two sides of the top portion. Each of the side portions connects with a bottom portion to be fixed on a steel frame forming a roof. A fastening member is fixed to the top portion of the base frame to form an assembling space for solar panels therebetween. A plurality of rubber strips for waterproofing and insulating from electricity are disposed between the side portions and the solar panels and between the fastening member and the solar panels. 1. A waterproof and electricity-insulating support structure for solar panels comprising:a base frame having a top portion with two side portions disposed at two sides of the top portion, each of the side portions connected with a bottom portion to be fixed on a steel frame forming a roof;a fastening member being fixed to the top portion of the base frame to form an assembling space for solar panels therebetween; anda plurality of rubber strips for waterproofing and insulating from electricity disposed between the side portions and the solar panels and between the fastening member and the solar panels.2. The waterproof and electricity-insulating support structure of claim 1 , wherein each of the side portions of the base frame comprises a first vertical section and a second vertical section not taller than the first vertical section claim 1 , a horizontal section connects the first vertical section and the second vertical section claim 1 , each of the first vertical section and the horizontal section couples with one said rubber strip.3. The waterproof and electricity-insulating support structure of claim 2 , wherein a groove for draining and ventilating is disposed at a junction of the horizontal section and the first vertical section. The present invention relates to a support frame, and more particularly to a support frame for assembling solar panels.Solar panels generate ...

METHOD FOR INDOOR LOCALIZATION USING NOMADIC ACCESS POINTS

A method for indoor localization using nomadic access points, comprising the following steps: a target object transmits a modulated signal over wireless channels to nearby access points, wherein the access points include both static access points and nomadic access points; the access points measure channel state information via the signal from the target object, after that, the static access points export the channel state information to a server, the nomadic wireless access point report the channel state information along with their coordinates of the current sites to the server; and based on the channel state information, the server determines the target object's relative proximity to two arbitrary access points, then based on the result of the relative proximity determination and the coordinates, the server estimates a feasible region for the target object with a space partition-based algorithm. 1. A method for indoor localization using nomadic access points , comprising the following steps:a target object transmitting a modulated signal over wireless channels to nearby access points, wherein the access points comprise both static access points and nomadic access points;the access points measuring channel state information via the modulated signal from the target object, after that, the static access points exporting the channel state information to a server, the nomadic access points reporting the channel state information along with current coordinates of the nomadic access points to the server; andbased on the channel state information, the server determining the target object's relative proximity to two arbitrary access points, then based on a result of the relative proximity determination and coordinates of both the static access points and the nomadic access points, the server estimating a feasible region for the target object by using a space partition-based algorithm.2. The method as claimed in claim 1 , wherein after the step of the server estimating the ...

PHOTOCATALYST MATERIAL AND METHOD FOR FABRICATING THE SAME

The disclosure provides a photocatalyst material and a method for fabricating the same. The photocatalyst material includes a zinc oxide material doped with metal, wherein the zinc oxide material has a lattice structure including a plurality of defects. A part of the defects are filled with a metal, 1. A photocatalyst material , comprising:a zinc oxide material doped with metal, wherein the zinc oxide material has a lattice structure comprising a plurality of defects, and a part of the defects are filled with a metal.2. The photocatalyst material as claimed in claim 1 , wherein the lattice strut ure is constructed by zinc atoms and oxygen atoms.3. The photocatalyst material as claimed in claim 1 , wherein the defects comprise zinc vacancy claim 1 , oxygen vacancy claim 1 , or a combination thereof.4. The photocatalyst material as claimed in claim 1 , wherein the metal filled into the defect is a single metallic atom.5. The photocatalyst material as claimed in claim 1 , wherein the metal filled into the defect contains a plurality of metallic atoms.6. The photocatalyst material as claimed in claim 1 , wherein the metal is Ag claim 1 , Cu claim 1 , Au claim 1 , Ni claim 1 , Co claim 1 , Fe claim 1 , Pd claim 1 , Pt claim 1 , Rh claim 1 , Ru claim 1 , or a combination thereof.7. The photocatalyst material as claimed in claim 1 , wherein the defects filled with the metal has a percentage of 5% to 99% claim 1 , based on the total defects of the lattice structure.8. The photocatalyst material as claimed in claim 1 , wherein the defects filled with the metal has a percentage of 40% to 93% claim 1 , based on the total defects of the lattice structure.9. The photocatalyst material as claimed in claim 2 , wherein the ratio between atoms of the metal and the zinc atoms of the zinc oxide material is between 0.00003 and 0.2.10. The photocatalyst material as claimed in claim 2 , wherein the ratio between atoms of the metal and the zinc atoms of the zinc oxide material is between ...

Projection Module and Terminal

A projection module and a terminal are provided. The projection module includes a base, a housing, a first light source, a second light source and an optical element. The housing is disposed on the base, and defines an accommodating cavity together with the base. The first light source is disposed on the base and arranged in the accommodating cavity. The second light source is disposed on the base and arranged in the accommodating cavity. The optical element is disposed on the housing and includes a diffraction area and a diffusion area. The first light source aligns with the diffraction area, the second light source aligns with the diffusion area, the diffraction area is configured to diffract light passing through the diffraction area, and the diffusion area is configured to diffuse light passing through the diffusion area. 1. A projection module , comprising:a base;a housing disposed on the base and defining an accommodating cavity together with the base;a first light source disposed on the base and arranged in the accommodating cavity;a second light source disposed on the base and arranged in the accommodating cavity; andan optical element disposed on the housing and comprising a diffraction area and a diffusion area, the first light source aligning with the diffraction area, the second light source aligning with the diffusion area, the diffraction area being configured to diffract light passing through the diffraction area, and the diffusion area being configured to diffuse light passing through the diffusion area.2. The projection module according to claim 1 , further comprising a spacer configured to divide the accommodating cavity into a first cavity and a second cavity claim 1 , the first light source being arranged in the first cavity claim 1 , and the second light source being arranged in the second cavity.3. The projection module according to claim 2 , wherein the spacer has one end abutting against the base claim 2 , and the other end abutting against ...

Platform-independent method and system for electronically engaging customers

Techniques for electronically engaging customers across all different platforms are disclosed. Based on unique device identifiers captured together with interactions by users with one or more applications provided by a business, a message prepared in a first format is automatically converted to a corresponding message in a second format according to what the devices the user have been interacting with can support. Depending on implementation, the message may be a response by the business to an inquiry from a user or a promotion by the business to be distributed to a group of selected users maintained by the business. The interactions include activities a user has had with one or more of the applications provided by the business and provide the statistical or actual data for the business to determine the group of users to receive the message. 1. A method for providing platform-independent customer engagement , the method comprising:determining a group of users by a server to receive a message, the message including data portions in text and multimedia prepared in a first format;retrieving at least some data capturing interactions by the users with a plurality of applications provided by a business entity, wherein the data is stored in a store coupled with the server was previously captured over a period of time from devices respectively associated with the users, the data pertains to respective activities by the users with at least one of the applications running on the devices; determining from the data what type of a device the each of the users has used; and', 'determining which one of the applications the each of the users has interacted;, 'deriving from the data a communication channel for each of the users, wherein said deriving from the data a communication channel for each of the users comprisesconverting the message per the communication channel to a second format supported by one of the applications used by the each of the users when the first format is not ...

SYSTEM AND METHOD FOR BIPHASIC TRANSDERMAL IONTOPHORETIC DELIVERY OF THERAPEUTIC AGENTS

Various embodiments provide methods and systems for the biphasic iontophoretic transdermal delivery of therapeutic agents. An embodiment of a method for such delivery comprises positioning at least one electrode assembly in electrical communication with a patient's skin. The assembly includes a solution comprising a therapeutic agent which passively diffuses into the skin. A dose of agent is delivered from the assembly into the skin during a first period using a first current having a characteristic e.g., polarity and magnitude, to repel the agent out of the assembly. During a second period, a second current having a characteristic to attract the agent is used to retain the agent in the assembly such that delivery of agent into skin is minimized. A dose of agent may be delivered on demand by an input from the patient. Embodiments may be used for delivery of agents which cause adverse effects from unwanted passive diffusion. 1a patch for iontophoretic transdermal delivery of the therapeutic agent, the patch having a tissue contacting side, a non-tissue contacting side, a therapeutic agent reservoir and a first and second electrode, at least one of the electrodes electrically coupled to the therapeutic agent reservoir;a current source coupled to the patch and electrically coupled to the first and second electrode; anda controller coupled to the patch for controlling the iontophoretic transdermal delivery of the therapeutic agent; the controller configured to deliver a dose of therapeutic agent from the patch into the skin during a first period using a first current having a polarity and magnitude to repel the therapeutic agent out of the patch; and retain the therapeutic agent in the patch during a second period using a second current having a polarity and magnitude to retain the therapeutic agent in the patch such that delivery of the therapeutic agent into the skin during the second period is minimized, wherein the first period comprises a delivery period and the ...

CAMERA MODULE, CONTROL METHOD, AND ELECTRONIC DEVICE

Provided are a camera module, a control method, and an electronic device. The camera module includes protective glass, a light-emitting component, and a light-receiving component. The protective glass is configured to shield and protect the light-emitting component and the light-receiving component. The protective glass includes a glass substrate and a glass groove. The glass groove is made on a glass surface of the glass substrate. 1. A camera module , comprising:protective glass:a light-emitting component: anda light-receiving component, wherein the protective glass is configured to shield and protect the light-emitting component and the light-receiving component, the protective glass comprises a glass substrate and a glass groove, and the glass groove is made on a glass surface of the glass substrate.2. The camera module according to claim 1 , wherein the glass substrate is configured to:refract a laser signal emitted by the light-emitting component, perform N reflections of the laser signal inside the glass substrate, and transmit a first reflected light signal formed after an N-th reflection to the glass groove, wherein N is a positive integer; andwherein the glass groove is configured to perform an (N+1)-th reflection of the first reflected light signal to control the first reflected light signal not to enter the light-receiving component, wherein a direction of a path along which the first reflected light signal propagates after the (N+1)-th reflection is opposite to a direction of a path along which the first reflected light signal propagates after the N-th reflection.3. The camera module according to claim 2 , wherein when the laser signal is emitted at a maximum emission angle claim 2 , N is equal to 1.4. The camera module according to claim 2 , wherein the glass surface comprises an upper glass surface and a lower glass surface; andwherein the glass substrate is configured to: refract the laser signal via the lower glass surface to form refracted light, ...

COMPACT THREE-WAY DOHERTY AMPLIFIER MODULE

Embodiments of a method and a device are disclosed. In an embodiment, a Doherty amplifier module includes a substrate including a mounting surface, and further includes a first amplifier die, a second amplifier die, and a third amplifier die on the mounting surface. The first amplifier die is configured to amplify a first radio frequency (RF) signal along a first signal path, the second amplifier die is configured to amplify a second RF signal along a second signal path, and the third amplifier die is configured to amplify a third RF signal along a third signal path. A side of the first amplifier die including a first output terminal faces a side of the second amplifier die including a second output terminal. The second signal path is parallel to the first signal path, and the third signal path is orthogonal to the first and second signal paths. 1. A Doherty amplifier module comprising:a substrate including a mounting surface;a first amplifier die on the mounting surface, the first amplifier die comprising a first input terminal proximate to a first side of the first amplifier die and a first output terminal proximate to a second side of the first amplifier die, the first amplifier die configured to amplify a first radio frequency (RF) signal along a first signal path to produce a first amplified RF signal at the first output terminal, the first signal path extending from the first side of the first amplifier die to the second side of the first amplifier die;a second amplifier die on the mounting surface, the second amplifier die comprising a second input terminal proximate to a first side of the second amplifier die and a second output terminal proximate to a second side of the second amplifier die, the second amplifier die configured to amplify a second RF signal along a second signal path to produce a second amplified RF signal at the second output terminal, the second signal path extending from the first side of the second amplifier die to the second side of the ...

BICMOS CURRENT REFERENCE CIRCUIT

A BiCMOS current reference circuit includes a reference core, a startup circuit, and a reference current output circuit. The reference core contains a current mirror, a positive temperature coefficient current generator, and a negative temperature coefficient current generator. The current mirror generates matching branch current. The positive and negative temperature coefficient currents were added in certain proportion to generate a reference current with zero temperature coefficient at room temperature. The startup circuit starts the reference core at power-on. The reference current output circuit proportionably outputs reference current generated by the reference core. Compared with the conventional voltage reference, the circuit uses current conveying technique, so it won't be affected by DC voltage drops of power supply network, and it features low transmission loss, good matching, excellent temperature stability, small chip size and auto-startup at power-on. It's preferably suitable for applications where A/D and D/A converters require accurate reference signals. 1. A Bipolar Complementary Metal Oxide Semiconductor (BiCMOS) current reference circuit , comprising a startup circuit , a reference core circuit , and a reference current output circuit , wherein:the startup circuit, for starting the reference core circuit at power on;the reference core circuit, for generating reference current with zero temperature coefficient at room temperature by canceling positive temperature coefficient current with negative temperature coefficient current; andthe reference current output circuit, for proportionably outputting reference current generated by the reference core circuit.2. The BiCMOS current reference circuit of claim 1 , wherein the reference core circuit comprises a first reference core transistor claim 1 , a second reference core transistor claim 1 , a third reference core transistor claim 1 , a fourth reference core transistor claim 1 , a fifth reference core ...

Vr motion control method, multi-dimensional motion platform and thrust universal spherical plain bearing

A system for virtual reality (VR) motion control includes a multi-dimensional motion platform and a thrust universal spherical plain bearing. The VR motion control method includes: setting parameters; calibrating a device; obtaining parameters; receiving a head-mounted display device tracking packet and/or an action control packet; determining whether a real-time angle difference is greater than a set dead zone angle; and calculating a difference between a current angle of a head-mounted display device and a current status of the multi-dimensional motion platform, and feeding the difference into an action control system of the multi-dimensional motion platform, to eliminate the difference. The multi-dimensional motion platform uses single-point bearing or single-point lifting bearing and lever traction-type transmission, thereby realizing functions of swinging and rotating in all directions. The thrust universal spherical plain bearing integrates a common thrust universal spherical plain bearing with a plane thrust bearing.

BAND-GAP REFERENCE CIRCUIT BASED ON TEMPERATURE COMPENSATION

A band-gap reference circuit includes a proportioned current generating circuit, a startup circuit, a current mirror circuit, a high-order temperature compensation generating circuit and a reference generating circuit. The proportioned current generating circuit is configured to generate a current in direct proportion to the absolute temperature. The startup circuit is configured to start up the proportioned current generating circuit when the startup circuit is power on. The current mirror circuit is configured to reproduce a current which is the same as the current in direct proportion to the absolute temperature. The high-order temperature compensation generating circuit is configured to generate a compensation current of high-order temperature coefficient. The reference generating circuit is configured to add the voltage which is generated by the proportioned current generating circuit to a voltage of negative temperature coefficient according to a certain proportion, and output a reference voltage of zero temperature coefficient. 1. A band-gap reference circuit based on temperature compensation , the circuit comprising:a proportioned current generating circuit configured to generate a current in direct proportion to the absolute temperature;a startup circuit configured to start up the proportioned current generating circuit when the startup circuit is power on;a current mirror circuit configured to reproduce a current which is the same as the current in direct proportion to the absolute temperature;a high-order temperature compensation generating circuit configured to generate a compensation current of high-order temperature coefficient; anda reference generating circuit configured to add the voltage which is generated by the proportioned current generating circuit to a voltage of negative temperature coefficient according to a certain proportion, and output a reference voltage of zero temperature coefficient.2. The band-gap reference circuit based on ...

Device for film thickness measurement and method for film thickness measurement

The embodiments of the invention disclose a device for film thickness measurement and a method for film thickness measurement. The device comprises a planar indenter, a collecting unit and a processing unit. The planar indenter comprises a base plate and a piezoelectric film layer. The collecting unit comprises a plurality of collecting circuits evenly distributed above the piezoelectric film layer and spaced from each other. The collecting circuits are used for collecting current signals generated when the piezoelectric film layer deforms at positions corresponding to the collecting circuits. The processing unit is used for calculating a film thickness of the film sample to be measured based on the current signals collected by each of the collecting circuits.

METHOD FOR INCREASING THE LIKELIHOOD TO INDUCE BEHAVIOR CHANGE IN A LIFESTYLE MANAGEMENT PROGRAM

A method and corresponding system for increasing the likelihood of inducing behavior change in a lifestyle management program for a user includes sensing at least one behavior parameter of a user; identifying at least one intention-behavior gap based on the sensing of the behavior parameter; via application of a genetic algorithm generating a quantified profile of the intention-behavior gap; via a user interface, suggesting at least one action to accept or reject; and varying the quantified profile based on the action accepted or rejected by the user. The user interface may include a smart phone that includes at least one sensor for sensing location and activity of a user of the user interface, or a dedicated device that communicates with a sensor for sensing a behavior parameter, or the sensor is disposed on the body of the user or on a garment worn by the user. 1. A method performed by one or more computing resources , comprising:providing a quantified intention-behavior gap profile for a user that influences a gap between an intention to perform a behavior and actual performance of the behavior, a size of the gap based on a plurality of mediating factors, the plurality of mediating factors based on properties of the user, a defined action, and a context in which the defined action is to be performed;monitoring a current level of performance of the user;accessing a performance goal for the user and a calendar comprising a planned behavior changing action and a context associated with the planned behavior changing action;comparing the current level of performance of the user, a performance level of the planned behavior changing performance, and the performance goal;determining if the user will reach the performance goal based on the comparison; and providing a first suggested action to be planned, the first suggested action based on combining a first set of action properties, a first set of context properties, and a first set of mediating factors that reduce the ...

Fagopyrum Nutraceutical Compositions

nutraceuticals and methods of their use are provided. The disclosed nutraceuticals are useful to improve or increase liver function and to treat liver diseases, especially those caused by viral hepatitis. In some embodiments, the nutraceuticals also contain supplementary botanical extracts to confer additional health benefits. 1Fagopyrum dibotyo. A nutraceutical composition comprising an amount of extract effective to inhibit viruses that affect the liver.2Fagopyrum dibotyo. The composition of comprising 0.1 mg to 10 g of extract claim 1 , and optionally an excipient.3. The composition of claim 1 , further comprising 0.001% to 50% of 5 claim 1 ,7 claim 1 ,3′ claim 1 ,4′-tetrahydroxyflavan-3-ol C-Cdimers.4. The composition of claim 1 , further comprising 0.001% to about 50% of derivatives of 5 claim 1 ,7 claim 1 ,3′ claim 1 ,4′-tetrahydroxyflavan-3-ol C-Cdimers.5. The composition of further comprising other herbal compounds claim 1 , extracts claim 1 , or molecules.6Semen cassiaeSpica prunellaePlantago depressaTaraxacum mongolicumThlaspi arvenseArtemisia capillaris. The composition of claim 5 , wherein the herbal compounds or extracts are selected from the group consisting of green tea extract claim 5 , milk thistle extract claim 5 , extract claim 5 , extract claim 5 , Wild. claim 5 , Hand-Mazz. claim 5 , radix claim 5 , forsythia claim 5 , Linn claim 5 , Thunb claim 5 , Tai zi shen claim 5 , poria claim 5 , or a combination thereof.7. The composition of claim 1 , further comprising a second therapeutic selected from the group consisting of an anti-inflammatory medication claim 1 , a diuretic claim 1 , an anti-cancer medication claim 1 , or combinations thereof.8. The composition of claim 1 , wherein the composition is formulated for oral administration.9. A method of inhibiting viral hepatitis in a subject in need thereof comprising administering to the subject an effective amount of the nutraceutical composition of .10. The method of wherein the subject in need ...

METHOD FOR PRODUCING SHAPED GRAPHENE SHEETS

Disclosed is a method of producing shaped graphene sheets, and the method includes the steps of providing an initial material of an artificial oriented graphite, performing a shaping process of the initial material of the artificial oriented graphite to produce a composite material, and carrying out an electrochemical process of the composite material to obtain the shaped graphene sheets, so as to achieve the mass production of high-quality shaped graphene sheets with a low cost. 1. A method of producing shaped graphene sheets , comprising the steps of:(A) providing an initial material of an artificial oriented graphite, and performing a shaping process of the initial material of the artificial oriented graphite to obtain a laminated material;(B) using an electrochemical method to process the laminated material, wherein the electrochemical method includes an electrolyte solution;(C) filtering the electrolyte solution to obtain a shaped graphene sheet.2. The method of producing shaped graphene sheets according to claim 1 , wherein the shaping process is a process selected from the collection of squeezing claim 1 , extrusion claim 1 , injection claim 1 , spinning claim 1 , snagging claim 1 , mold pressing claim 1 , spray coating claim 1 , coating claim 1 , scraping and hot pressing process.3. The method of producing shaped graphene sheets according to claim 1 , wherein the initial material of the artificial oriented graphite is one selected from the collection of carbon fibers with a radial crystal orientation of graphite claim 1 , a radial graphite fiber claim 1 , a parallel oriented carbon fiber claim 1 , a parallel oriented graphite fiber claim 1 , a parallel oriented fiber lump claim 1 , a parallel oriented fiber graphite sheet claim 1 , and a coaxially parallel oriented graphite nanocrystal material.4. The method of producing shaped graphene sheets according to claim 3 , wherein the coaxially parallel oriented graphite nanocrystal material is one selected from ...

Method for Relieving Vaulted Expansion of Cement-Stabilized Base Layer Through Precut Seams

The present invention discloses a method for relieving vaulted expansion of a cement-stabilized base layer through precut seams. The method firstly establishes an RBFN model according to a large number of observation results of a vaulted expansion amount of the cement-stabilized base layer under different conditions (such as temperature and a stress release structure) in Xinjiang and similar regions; and on such a basis, the vaulted expansion amount of the cement-stabilized base layer to be designed is predicted. When the vaulted expansion amount is greater than a control requirement, the RBFN model is configured to design a reasonable width and a reasonable interval of the precut wide expansion seams to ensure that the vaulted expansion amount of the cement-stabilized base layer is less than a control value. Based on the design of the RBFN model, the present invention provides a corresponding construction method for the precut wide expansion seams. The present invention can predict the vaulted expansion of the cement-stabilized base layer without precut seams according to existing data. 1. A method for relieving vaulted expansion of a cement-stabilized base layer through precut seams , comprising the following steps:{'sub': k', 'k', 'k', 'k, 'figref': {'@idref': 'DRAWINGS', 'FIG. 1'}, '1) training a radial basis function network (RBFN) model, that is, establishing a mapping relationship between vaulted expansion amounts of the cement-stabilized base layer and different conditions through automatic adjustment of model parameters according to known vaulted expansion amounts of the cement-stabilized base layer under different temperatures and stress release structural conditions in a known region; wherein the training of the RBFN model refers to the automatic adjustment of RBFN model parameters wand caccording to a large number of vaulted expansion amounts of the cement-stabilized base layer under different conditions in the region, wand care a parameter weight ...

Non-Invasive, Continuous, Accurate and Cuff-Less Measurement of Blood Pressure and Other Cardiovascular Variables by Pulse Wave Acquisition and Analysis Using Non-Invasive Sensors

A method for noninvasively measuring hemodynamic variables of a person includes physically configuring a sensor to measure the pulse of a person. The sensor generates a pulse waveform indicative of the pulse of the person. A processor obtains the pulse waveform from the sensor and the processor determines a reflection coefficient and reflection delay between an incident and a reflected wave, from which the processor determines the hemodynamic variables of the person from the reflection coefficient and the reflection delay.

Systems and methods for image depth map generation

Systems and methods which provide generation of image depth maps which more accurately represent the local depth discontinuity within images through use of image global depth maps adapted based upon image global motion and/or localized depth analysis utilizing relative relationships of attributes across depth discontinuities in the image are disclosed. Embodiments utilize a full global depth map which is larger than or equal to the image being converted in order to accommodate image global motion, in generating an image global depth map. In operation according to embodiments, an image global depth map is identified within the full global depth map, such as based upon global motion within the image. Localized depth analysis, using pixel attribute relative relationships, is applied with respect to the image global depth map according to embodiments to generate an image depth map which more accurately reflects the local depth discontinuities within the image.

SYSTEM AND METHOD FOR DELEGATION OF PERMISSIONS TO A THIRD PARTY

A system and method for delegating permissions to a third party are presented. A request to access a first computing resource of a computer server is received from a first user. The first user is prompted to supply a first authentication credential for access to the first computing resource of the computer server and the first authentication credential is received from the first user. After the first authentication credential is received, a request to access a second computing resource of the computer server is received from the first user. An authentication database is accessed to identify a second user associated with the second computing resource, and a request for a second authentication credential is transmitted to a second user. The second authentication credential is received from the second user. When the second authentication credential is received from the second user, the first user is given access to the second computing resource. 1. A method , comprising:authenticating, by a computer server configured to communicate via a communications network, a website developer;after authenticating, by the computer server, the website developer, receiving from the website developer a request to access a computing resource of the computer server;providing the website developer temporary access to the computing resource, the temporary access to the computing expiring after a period of time;identifying, by the computer server, a user, wherein the computing resource is registered to the user;transmitting, by the computer server, to the user a request for an authentication credential granting the website developer access to the computing resource; andupon receiving, by the computer server, the authentication credential, providing the website developer permanent access to the computing resource.2. The method of claim 1 , wherein the request for the authentication credential is transmitted to the user using a short message service message.3. The method of claim 1 , wherein ...

Control Method for Electronic Device, Electronic Device and Computer Readable Storage Medium

A control method for an electronic device and an electronic device are provided. The electronic device includes an infrared emitter, an infrared sensor, and a visible light sensor. The control method includes: acquiring an original pixel position of a zero-level region on the infrared sensor; acquiring a human eye pixel position of a human eye region on the visible light sensor; determining whether a human eye enters the zero-level region according to the original pixel position and the human eye pixel position; and triggering a protection mechanism of the infrared emitter when the human eye enters the zero-level region.

METHOD FOR AUTOMATICALLY EXITING TRIAL RUN, DEVICE, AND SYSTEM

A method for automatically exiting trial run, a device, and a system are described. In a manner in which a packet that is sent by a first device running a network protocol client to a second device running a network protocol server and that is used to request trial run carries a condition set used to indicate the second device to exit trial run, the second device can automatically determine, in a process of performing trial run, whether the condition set is met, and automatically exit trial run when the condition set is met. This reduces a problem that in the trial run process of the second device, operation and maintenance personnel need to repeatedly confirm whether the second device needs to exit trial run, and a processing process is relatively complex. 1. A method for automatically exiting a trial run , comprising:obtaining, by a first device running a network protocol client, a condition set, wherein the condition set comprises at least one condition, and the at least one condition is a condition used to indicate a second device running a network protocol server to exit trial run;generating, by the first device, a first packet that is used to request the trial run, wherein the first packet carries the condition set; andsending, by the first device, the first packet to the second device.2. The method according to claim 1 , whereinthe at least one condition comprises a parameter and a value range of the parameter; orthe at least one condition comprises notification information, and the notification information comprises alarm information or event information.3. The method according to claim 1 , whereinthe condition set comprises a condition used to indicate a command of an action and a condition used to indicate an execution result of the action.4. The method according to claim 1 , wherein the first packet is one of a network configuration protocol NETCONF packet claim 1 , a remote login network protocol Telnet packet claim 1 , or a secure shell SSH protocol ...

ROCK SPECIMEN AND METHOD FOR TESTING DIRECT TENSILE STRENGTH OF THE SAME

A rock specimen, including a rock body having the shape of a cylinder or a regular square prism. The rock body includes: an upper end face, a first circular groove, a first cylinder, a first circular body, a lower end face, a second circular groove, a second cylinder, and a second circular body. The first circular groove is disposed on the upper end face of the rock body and has a circle center coinciding with the center of the upper end face of the rock body. The second circular groove is disposed on the lower end face of the rock body and has a circle center coinciding with the center of the lower end face of the rock body. The outer diameter of the first circular groove is smaller than the inner diameter of the second circular groove, and the first circular groove and the second circular groove are staggered. 2. The rock specimen of claim 1 , whereinthe diameter of the first cylinder is between ¼ and ⅓ of a diameter of the rock body having the shape of the cylinder or a side length of the rock body having the shape of the regular square prism; andthe diameter of the second cylinder is between 1.5 and 2 folds of the diameter of the first cylinder.3. The rock specimen of claim 1 , wherein a width of the first circular groove is between 2 and 10 mm; a width of the second circular groove is between 2 and 10 mm; a depth of the first circular groove is between ½ and ⅘ of a height of the rock body; and a depth of the second circular groove is between ⅔ and ⅘ of a height of the rock body.4. The rock specimen of claim 2 , wherein a width of the first circular groove is between 2 and 10 mm; a width of the second circular groove is between 2 and 10 mm; a depth of the first circular groove is between ½ and ⅘ of a height of the rock body; and a depth of the second circular groove is between ⅔ and ⅘ of a height of the rock body.5. The rock specimen of claim 3 , wherein the width of the first circular groove is between 3 and 5 mm; the width of the second circular groove is ...

Rock specimen and method for testing pure shear of the same

A rock specimen, including a rock body. The rock body includes: an upper part, an upper end face, a first circular groove, a first cylinder, a first circular body, a lower part, a lower end face, a second circular groove, a second cylinder, and a second circular body. The first circular groove is disposed on the upper end face of the rock body and has a circle center coinciding with a center of the upper end face. A method for testing pure shear of the rock specimen, includes: 1) disposing the rock specimen on a test bench of a rock mechanics testing system, allowing the end face of the second circular body to contact the test bench; and 2) operating the rock mechanics testing system, loading a pressure on the rock specimen via the end face of the first cylinder and the end face of the second circular body.

Gelable System Containing Ether Compounds, Preparation Method Therefor and Use Thereof

A gelable system is formed by mixing lithium salts and small-molecule ether compounds such as cyclic ether compounds or straight-chain ether compounds, optionally added with inorganic nanoparticles, additives, other solvents and/or electrolytes; a gel system or solid system is formed by interaction between them (such as the formation of new complexes or self-assembly, etc.), and by ring-opening polymerization or polycondensation of the small-molecule cyclic ether compounds, or by addition-fragmentation chain transfer polymerization of the small-molecule straight-chain ether compounds, etc. The gel system or solid system not only has better safety in use than common gel systems or solid systems, but also better adjustability of strength. The strength of the formed gel can be improved from the source by changing composition and type of raw materials. The improvement in the strength enables the gel system to be expanded into the solid system, thereby further extending the application range of the gel system.

SELECTING CONTENT WITH AN EXTERNAL LINK FOR PRESENTATION BASED ON USER INTERACTION WITH EXTERNAL CONTENT

An online system receives posts that include links to various external pages and presents those posts to users of the online system. When the online system determines an opportunity to present a post to a particular viewing user of the online system, the online system determines a quality metric and an associated value score for the post. The quality metric is determined as a likelihood that the viewing user will view the external page for less than a threshold time period, and is used to adjust the associated value score. The online system compares the value score of the post to the value scores of other posts and selects one or more of the compared posts for presentation to the viewing user of the online system. 1. A method comprising:accessing a post from a posting user of an online system, the post comprising a link to an external page that is outside the online system;determining an opportunity to present content to a viewing user of the online system;determining one or more attributes of the external page;determining a likelihood of the viewing user viewing the external page for less than a threshold time period based on the attributes of the external page determining a quality metric of the post for the viewing user based on the attributes of the determined likelihood of the viewing user viewing the external page for less than the threshold time period, where the quality metric decreases with a higher determined likelihood of the viewing user viewing the external page for less than the threshold time period;computing a value score presenting the post to the viewing user, the value score adjusted upward by the quality metric;ranking the post by its value score along with a plurality of other posts;selecting, based on the ranking, one or more of: the post and the plurality of other posts; andsending the selected posts for presentation to the viewing user.2. The method of claim 1 , wherein the determined quality metric of the post is a binary classifier based on ...

REDUCING SIGNALING LOAD CAUSED BY CHANGE OF TERMINAL LOCATION

A mobility management node and a method in a mobility management node for reducing signalling caused by changes of location of a radio terminal, which mobility management node is configured to be operatively comprised by a wireless communication system and to operatively manage the mobility of the radio terminal and to operatively communicate with a gateway node acting as an interface between the system and an external network. The method comprises obtaining initial position information; obtaining boundary information indicating a boundary area wherein at least one of a policy or a charging rule is to be applied for the radio terminal; obtaining current position information; determining whether the radio terminal is inside or outside the boundary area; providing mobility information when the radio terminal is outside the boundary area and not providing mobility information to the gateway node when the radio terminal is inside the boundary area. 116-. (canceled)17. A method in a mobility management node for reducing signalling caused by changes of location of a radio terminal , which mobility management node is configured to be operatively comprised by a wireless communication system and to operatively manage the mobility of the radio terminal and to operatively communicate with a gateway node acting as an interface between the system and an external network , wherein the method comprises:obtaining boundary information, which boundary information indicates a boundary area wherein at least one of a policy or a charging rule is to be applied for the radio terminal;obtaining current position information indicating the current position of the radio terminal;determining whether the radio terminal is inside or outside the boundary area based on the boundary information and the current position information; andsending a message comprising mobility information to the gateway node indicating the current position of the radio terminal when the radio terminal is outside the ...

Baseline Wander Compensation

A data recovery circuit provides compensation for baseline wander exhibited by a data signal. An adaptive equalizer generates a recovered data signal from a data input. A level shifter and low-pass filter provide a compensation signal as a function of the recovered data signal. An adaptation engine adjusts the level of the compensation signal to compensate for baseline wander. The adaptive equalizer generates the recovered data signal as a function of the data input and the compensation signal, thereby providing accurate recovery of the data signal. 1. A circuit comprising:an AC-coupling network configured to receive a data input signal and output a high-pass filtered data signal;an adaptive equalizer configured to output a recovered data signal;a level shifter configured to output a level-shifted signal as a function of the recovered data signal;a low-pass filter configured to output a low-pass filtered signal as a function of the level-shifted signal, the low-pass filtered signal corresponding to a low-frequency component of the data input signal, the adaptive equalizer generating the recovered data signal as a function of the low-pass filtered signal and the high-pass filtered data signal; andan adaptation engine configured to control a gain setting of the level shifter to adjust an amplitude of the level-shifted signal as a function of the recovered data signal.2. A circuit comprising:an AC-coupling network configured to receive a data input signal and output a high-pass filtered data signal;an adaptive equalizer configured to output a recovered data signal;a level shifter configured to output a level-shifted signal as a function of the recovered data signal;a low-pass filter configured to output a low-pass filtered signal as a function of the level-shifted signal, the low-pass filtered signal corresponding to a low-frequency component of the data input signal, the adaptive equalizer generating the recovered data signal as a function of the low-pass filtered ...

TOUCHPAD APPARATUS

A touchpad apparatus includes a housing, a movable member, and a touchpad substrate. The housing includes a first stepped portion provided with a plurality of steps. The steps gradually ascend along a rotation direction around an axis. The movable member is disposed on the housing and is configured to rotate relative to the housing around the axis. The movable member includes a first support portion selectively pressing against one of the plurality of steps. The touchpad substrate is configured to press against one end of the movable member away from the housing. By adjusting a distance between the movable member and the touchpad substrate, a pressing stroke of the touchpad is adjusted, so that a touch force is changed. 1. A touchpad apparatus , comprising:a housing including a first stepped portion provided with a plurality of steps, wherein the plurality of steps gradually ascend along a rotation direction around an axis;a movable member disposed on the housing and configured to rotate relative to the housing around the axis, the movable member including a first support portion, the first support portion selectively pressing against one of the plurality of steps; anda touchpad substrate configured to press against one end of the movable member away from the housing.2. The touchpad apparatus of claim 1 , wherein the housing further comprises a plurality of limiting grooves arranged around the axis claim 1 , and the movable member further comprises a limiting post selectively engaged with one of the plurality of limiting grooves.3. The touchpad apparatus of claim 2 , wherein each of the plurality of limiting grooves is provided with an opening having two opposite inclined surfaces claim 2 , a width between the two inclined surfaces gradually increases towards the touchpad substrate claim 2 , and the plurality of inclined surfaces of the plurality of openings are arranged around the axis.4. The touchpad apparatus of claim 1 , wherein the housing further comprises a ...

SYSTEMS AND METHODS FOR DETERMINING CUSTOMER LIFETIME VALUE

Systems and methods including one or more processors and one or more non-transitory storage devices storing computing instructions configured to run on the one or more processors and perform acts of storing, for each respective customer of one or more customers, respective customer information in a customer database; predicting, using a machine learning lifetime value (LTV) update model, a respective LTV for each respective customer of the one or more customers; determining an online advertisement for each respective customer of the one or more customers using the respective LTV, as predicted, for each respective customer of the one or more customers; and coordinating displaying the online advertisement for at least a portion of the one or more customers. Other embodiments are disclosed herein. 1. A system comprising:one or more processors; and storing, for each respective customer of one or more customers, respective customer information in a customer database;', 'predicting, using a machine learning lifetime value (LTV) update model, a respective LTV for each respective customer of the one or more customers;', 'determining an online advertisement for each respective customer of the one or more customers using the respective LTV, as predicted, for each respective customer of the one or more customers; and', 'coordinating displaying the online advertisement for at least a portion of the one or more customers., 'one or more non-transitory storage devices storing computing instructions configured to run on the one or more processors and perform2. The system of claim 1 , wherein the machine learning LTV update model comprises a two-stage machine learning LTV update model.3. The system of claim 1 , wherein determining the online advertisement for each respective customer of the one or more customers comprises:applying one or more LTV decay functions to the respective LTV, as predicted, for each respective customer of at least a portion of the one or more customers to ...

LOW SCALE POTENTIAL WATER TREATMENT

An electrochemical treating device having low scale potential is disclosed. The device has a variety of configurations directed to the layering of the anionic exchange and cationic exchange. The treatment device can also comprise unevenly sized ion exchange resin beads and/or have at least one compartment that provides a dominating resistance that results in a uniform current distribution throughout the apparatus. 139-. (canceled)40. An electrodeionization apparatus comprising:a depleting compartment at least partially defined by a cation selective membrane and an anion selective membrane; anda concentrating compartment at least partially defined by the anion selective membrane and containing a first layer of anion exchange media and a second layer of media disposed downstream of the first layer, the second layer comprising anion exchange media and cation exchange media.41. The electrodeionization apparatus of claim 40 , wherein the second layer comprises a first zone comprising cation exchange media that is substantially separated from the anion selective membrane by a second zone comprising anion exchange media.42. The electrodeionization apparatus of claim 40 , wherein the second layer is disposed downstream of the first layer.4351-. (canceled)52. A method of treating water comprising:introducing water to be treated into a depleting compartment of an electrodeionization device, the depleting compartment having at least one layer of ion exchange media; andpromoting transport of at least a portion of anionic species from the water introduced into the depleting compartment from a first layer of ion exchange media into a first concentrating compartment to produce water having a first intermediate quality, the first concentrating compartment defined at least partially by an anion selective membrane and a cation selective membrane, the first concentrating compartment containing at least partially a first zone comprising cation exchange media that is substantially ...

NEW PATTERN AND METHOD OF VIRTUAL REALITY SYSTEM BASED ON MOBILE DEVICES

A new pattern and method of a virtual reality system based on mobile devices, which may allow a player to design a virtual scene structure in a physical space and allow quick generation of corresponding 3D virtual scenes by a mobile phone; real rotation of the head of the player is captured by an acceleration sensor in the mobile phone by means of a head-mounted virtual reality device to provide the player with immersive experience; and real postures of the player are tracked and identified by a motion sensing device to realize player's mobile input control on and natural interaction with the virtual scenes. The system only needs a certain physical space and simple virtual reality device to realize the immersive experience of a user, and provides both a single-player mode and a multi-player mode, wherein the multi-player mode includes a collaborative mode and a versus mode. 1. A new pattern of a virtual reality system based on mobile devices , comprising a design pattern and a game pattern , wherein the design pattern comprises a scene design module , a correction module and a modeling module; the game pattern comprises a stereoscopic display module , a tracking module , a first interactive module and a second interactive module , whereinthe scene design module is configured to design corresponding scenes in a real space according to game types;the correction module is configured to photograph a scene structure in the real space to obtain a plan view of the designed scene structure, and perform image correction on the plan view to obtain a standard plan view;the modeling module is configured to obtain features of the scene structure as modeling information of three-dimensional scenes and send the features to clients of players to complete building of virtual scenes;the stereoscopic display module is configured to display images corresponding to left and right eyes on split screens of the client of each player, respectively, project the images into the eyes by means ...

Blockchain-based file handling

Blockchain-based file handling is provided by receiving a data file from a user device, storing the data file to local storage of the blockchain peer, generating a file identifier of the data file, providing the file identifier to the user device, storing the file identifier to a synchronized ledger of the blockchain network, where the synchronized ledger tracks access to the data file, and distributing data of the data file to one or more other blockchain peers of the blockchain network.

ANTI-CD40 ANTIBODY DRUG CONJUGATES

Provided herein are anti-CD40 antibody drug conjugates comprising a radical of Formula (I), wherein R, R, and Rare as defined herein. Further provided are anti-CD40 antibody drug conjugates of Formula (II), wherein Z, R, AA1, AA2, AA3, m, p, q, n, w, R, R, and Rare as defined herein. Further provided are pharmaceutical compositions and kits thereof, and methods of using same. 3. The antibody drug conjugate of claim 1 , wherein Ris hydrogen and Ris hydrogen.4. The antibody drug conjugate of claim 1 , wherein Ris fluoro and Ris hydrogen.5. The antibody drug conjugate of claim 1 , wherein Ris fluoro and Ris fluoro.6. The antibody drug conjugate of claim 1 , wherein Ris —P(═O)(OH).7. The antibody drug conjugate of claim 1 , wherein Ris hydrogen.8. The antibody drug conjugate of claim 1 , wherein -AA1-(AA2)-(AA3)- is selected from the group consisting of -Gly-Glu-; -Ala-Ala-; -Glu-Ala-Ala-; -Gly-Lys-; -Glu-; -Glu-Ser-Lys-; and -Gly-Ser-Lys-.912.-. (canceled)13. The antibody drug conjugate of claim 2 , wherein:m is 0 or 1;p is 1; andR is a bond14. The antibody drug conjugate of claim 2 , wherein R is a bond claim 2 , p is 1 claim 2 , m is 0 claim 2 , w is 0 claim 2 , and q is 0.15. The antibody drug conjugate of claim 2 , wherein R is a bond claim 2 , p is 1 claim 2 , m is 0 claim 2 , w is 0 claim 2 , and q is 1.1617.-. (canceled)18. The antibody drug conjugate of claim 1 , selected from the group consisting of compounds listed in Table 5 claim 1 , wherein n is 1 claim 1 , 2 claim 1 , 3 claim 1 , 4 claim 1 , 5 claim 1 , 6 claim 1 , 7 claim 1 , 8 claim 1 , 9 claim 1 , or 10.19. (canceled)20. The antibody drug conjugate of claim 1 , selected from the group consisting of compounds listed in Table 6A claim 1 , wherein n is 1 claim 1 , 2 claim 1 , 3 claim 1 , 4 claim 1 , 5 claim 1 , 6 claim 1 , 7 claim 1 , 8 claim 1 , 9 claim 1 , or 10.21. (canceled)22. The antibody drug conjugate of claim 1 , selected from the group consisting of compounds listed in Table 6B claim 1 , wherein ...

Controlling drug delivery transitions

Devices, systems, and techniques for transitioning between different drug delivery sources or different drug concentrations may account for diffusion and mixing of drug within the fluid. In one example, a method may include determining a flow rate for a fluid to be delivered to a patient via a drug pump and a catheter in fluid communication with a reservoir of the drug pump. The fluid includes a drug. The method also includes determining a concentration profile of the drug delivered via the catheter, wherein the concentration profile identifies a volume of delivered fluid needed to achieve a target transition dose of the drug. The method further includes determining, by a processor and based on the flow rate and the concentration profile, an initial delivery period required to achieve the target transition dose by delivering the fluid at the flow rate.

DISPLAY SUBSTRATE, FABRICATING METHOD THEREOF AND DISPLAY DEVICE

The present disclosure provides a display substrate, a fabricating method thereof, and a display device. The method includes forming a light shielding layer on a surface of a base substrate, and forming a plurality of thin film transistors on a side of the light shielding layer away from the base substrate. Forming a plurality of thin film transistors on a side of the light shielding layer away from the base substrate includes forming a semiconductor layer at a position where an active layer is to be formed in each of the plurality of thin film transistors, generating heat using the light shielding layer, and utilizing the heat to crystallize the semiconductor layer. 1. A method for fabricating a display substrate , comprising:forming a light shielding layer on a surface of a base substrate; andforming a plurality of thin film transistors on a side of the light shielding layer away from the base substrate,wherein forming the plurality of thin film transistors on the side of the light shielding layer away from the base substrate comprises:forming a semiconductor layer at a position where an active layer is to be formed in each of the plurality of thin film transistors;generating heat using the light shielding layer; andutilizing the heat to crystallize the semiconductor layer.2. The method according to claim 1 ,wherein a material of the light shielding layer comprises a conductive material, andwherein generating heat using the light shielding layer comprises energizing the light shielding layer.3. The method according to claim 2 ,wherein the light shielding layer comprises a plurality of sub-light shielding layers disposed at intervals,wherein the plurality of thin film transistors comprises a plurality of thin film transistor groups,wherein an orthographic projection of each of the plurality of sub-light shielding layers on the base substrate covers an orthographic projection of active layers in a corresponding thin film transistor group on the base substrate, ...

MULTI-TERMINATION SCHEME INTERFACE

In an embodiment, a method includes programming a control signal that specifies a target resistance and a target voltage in a circuit. The method further includes sending the control signal to at least one transistor configured to control a current flow in the circuit. The method further includes providing, as an output, a signal with the target voltage and target resistance. 1. A method comprising:programming a plurality of control signals that specify a target resistance and a target voltage in a circuit;generating a plurality of gate signals, the plurality of gate signals based on the plurality of control signals;sending the plurality of gate signals to at least one transistor configured to control a current flow in the circuit; andproviding, as an output, a signal with the target voltage and target resistance.2. The method of claim 1 , whereinthe at least one transistor includes a first transistor, a second transistor, and a third transistor;the first transistor is coupled to allow current to flow between a voltage source and a first resistor;the second transistor is coupled to allow current to flow between ground and a second resistor;the third transistor is coupled to allow current to flow between ground and a third resistor;the first resistor, the second resistor, and the third resistor are further coupled with a printed circuit board (PCB) trace, the PCB trace receiving a transmission from a driver;a product of a second resistance of the second resistor and a third resistance of the third resistor divided by a sum of the second resistance and the third resistance produces the target resistance;the second resistance divided by the sum of the first resistance and the second resistance times a voltage of the voltage source is the target voltage.3. The method of claim 2 , wherein:a first control signal, configured to be in a first state, coupled to a gate of the first transistor is configured to allow current to flow through the first transistor;a second control ...

PHOTOELECTRIC SENSOR AND PHOTOELECTRIC TOUCH PANEL

A photoelectric sensor, comprising: a first thin film transistor (T) for converting a photo signal into an electrical signal; a second thin film transistor (T) for performing an integration operation on the electrical signal; a third thin film transistor (T) for reading the electrical signal; and a first capacitor (C) for storing an energy of the electrical signal, wherein a drain electrode of the first thin film transistor (T) is connected to one end of the first capacitor (C) and a source electrode of the third thin film transistor (T); a source electrode of the first thin film transistor (T) is connected to a drain electrode of the second thin film transistor (T); a gate electrode of the first thin film transistor (T) is supplied with a bias signal; wherein a gate electrode of the second thin film transistor (T) is supplied with an integration signal; a source electrode of the second thin film transistor (T) is connected to a high level end of a power source; the other end of the first capacitor (C) is connected to a low level end of the power source; and wherein a gate electrode of the third thin film transistor (T) is supplied with a scan signal; a drain electrode of the third thin film transistor (T) is configured to output the read electrical signal. 1. A photoelectric sensor , comprising:{'b': '1', 'a first thin film transistor (T) for converting a photo signal into an electrical signal;'}{'b': '2', 'a second thin film transistor (T) for performing an integration operation on the electrical signal;'}{'b': '3', 'a third thin film transistor (T) for reading the electrical signal; and'}{'b': '1', 'a first capacitor (C) for storing an energy of the electrical signal,'}{'b': 1', '1', '3', '1', '2', '1, 'wherein a drain electrode of the first thin film transistor (T) is connected to one end of the first capacitor (C) and a source electrode of the third thin film transistor (T); a source electrode of the first thin film transistor (T) is connected to a drain ...

Electronic Commerce Platform and Transaction Method Using the Same

An electronic commerce platform is communicatively connected to a plurality of electronic devices each of which including a carrier. The electronic commerce platform includes a commodity managing module and a server. The commodity managing module is configured to receive at least a commodity information having a commodity characteristic and to transmit the commodity information to the server. The server includes a shopping interface producer and a match module. The shopping interface producer is configured to produce a shopping interface based on the commodity information. The match module is configured to transmit the commodity information to a matched carrier. The electronic device is configured to be communicatively connected to the shopping interface when a user clicks the commodity information shown on the carrier. 1. An electronic commerce platform communicatively connected to at least an electronic device , the electronic device including a carrier , the electronic commerce platform including:a commodity managing module configured to receive at least one commodity information having a commodity characteristic thereof and transmit the at least one commodity information to a server, and the server including:a shopping interface producer configured to produce a shopping interface based on the commodity information; anda match module configured to transmit the commodity information to a matched carrier based on the commodity characteristic of the commodity information;wherein the electronic device is configured to be communicatively connected to the shopping interface when a user clicks the commodity information shown on the carrier.2. The electronic commerce platform of claim 1 , wherein the carrier further comprises a shop window module configured to receive the commodity information.3. The electronic commerce platform of claim 1 , wherein the electronic device is a smart phone claim 1 , a tablet claim 1 , a notebook or a desk-top computer.4. The electronic ...

COMPOSITIONS AND METHODS FOR THE TREATMENT OF VprBP-RELATED CANCERS

This disclosure provides methods and compositions to inhibit or suppress tumor growth or to treat cancer by inhibiting VprBP kinase activity. Also provided are methods of determining the effectiveness of the methods and compositions to inhibit or suppress tumor growth or to treat cancer by inhibiting VprBP kinase activity, methods for detecting a cancer, and methods for screening potential agents that inhibit VprBP kinase activity. 1. A method for on or more of:a. inhibiting the growth of a cancer cell;b. activating tumor suppressor function in a cell comprising functional tumor suppressor genes; andc. inhibiting H2AT120P in a cell comprising functional H2AT120P,{'claim-ref': [{'@idref': 'CLM-00003', 'claim 3'}, {'@idref': 'CLM-00004', '4'}], 'comprising contacting the cell with an effective amount of an agent that inhibits VprBP kinase activity in the cell, wherein the agent is the composition of or .'}2. A method for inhibiting the growth of a cancer cell in a patient or treating cancer in a patient , comprising administering to the patient in need thereof an effective amount of the composition of or .3. A composition comprising a carrier and a VprBR kinase-specific RNAi.4. The composition of claim 3 , wherein VprBR kinase-specific RNAi is selected from the group of reference polynucleotides of consisting of VprBP shRNA1 (SEQ ID NO: 1: 5′-CGAGAAACTGAGTCAAATGAA-3′) claim 3 , VprBP shRNA2 (SEQ ID NO: 2: 5′-AATCACAGAGTATCTTAGA-3′) and Bub1 shRNA (SEQ ID NO: 3:5′-CGAGGTTAATCCAGCACGTAT-3′) claim 3 , or an equivalent thereof claim 3 , wherein an equivalent of each thereof claim 3 , wherein an equivalent thereof comprises a polynucleotide that has at least 80% sequence identity to the reference polynucleotide and inhibits VprBP kinase activity or a polynucleotide that hybridizes under conditions of high stringency to the reference polynucleotide or its complement claim 3 , wherein conditions of high stringency comprise hybridization reaction at about 60° C. in about 1× ...

INDUCED COMMON ANTIBODY RESPONSE

A method of inducing a generalized immune response, includes administering to a subject an immunologically effective amount of one or more isolated immunogenic peptides comprising an amino acid sequence of SEQ. ID NOs: 1-46, thereby inducing a generalized immune response to infection by a pathogen in a subject. A prophylactic or therapeutic composition for inducing a generalized immune response, includes an immunologically effective amount of one or more isolated immunogenic peptides comprising an amino acid sequence of SEQ. ID NOs: 1-46. A method of distinguishing a subject infected with a pathogen from an uninfected subject, includes detecting an antibody in the subject that selectively binds one or more isolated immunogenic peptides comprising an amino acid sequence of SEQ. ID NOs: 1-46, wherein the presence of the antibody indicates that the subject is infected with the pathogen. A general method to discover broadly protective components for a vaccine is also disclosed. 1. A method of inducing a generalized immune response to infection by a pathogen in a subject , comprising:selecting a subject for treatment that has, or is at risk for developing, an infection by a pathogen;administering to a subject a immunologically effective amount of one or more isolated immunogenic peptides or nucleic acid encoding the one or more isolated immunogenic peptides wherein the one or more isolated immunogenic peptides comprises an amino acid sequence set forth as SEQ. ID NO: 1, SEQ. ID NO: 2, SEQ. ID NO: 3, SEQ. ID NO: 4, SEQ. ID NO: 5, SEQ. ID NO: 6, SEQ. ID NO: 7, SEQ. ID NO: 8, SEQ. ID NO: 9, SEQ. ID NO: 10, SEQ. ID NO: 11, SEQ. ID NO: 12, SEQ. ID NO: 13, SEQ. ID NO: 14, SEQ. ID NO: 15, SEQ. ID NO: 16, SEQ. ID NO: 17, SEQ. ID NO: 18, SEQ. ID NO: 19, SEQ. ID NO: 20, SEQ. ID NO: 21, SEQ. ID NO: 22, SEQ. ID NO: 23, SEQ. ID NO: 24, SEQ. ID NO: 25, SEQ. ID NO: 26, SEQ. ID NO: 27, SEQ. ID NO: 28, SEQ. ID NO: 29, SEQ. ID NO: 30, SEQ. ID NO: 31, SEQ. ID NO: 32, SEQ. ID NO: 33, SEQ. ...

AUXILIARY SENSING METHOD AND SYSTEM BASED ON SENSORY SUBSTITUTION

An auxiliary sensing method and system based on sensory substitution includes: establishing a discrete horizontal plane included angle and a normal vector included angle in three-dimensional space as well as response functions corresponding to different discrete distances, and establishing an acoustic coding library of an object; obtaining a surrounding environmental video; obtaining object information and category of current environment; establishing a three-dimensional sound field of the object according to the image information, the object information and the three-dimensional coordinate information obtained in combination with the acoustic coding library of the object; and adjusting, for objects of different categories, the three-dimensional sound field of each object according to movement information and variations of images, and playing the three-dimensional sound field of each object in real time. 1. An auxiliary sensing method based on a sensory substitution , comprising:step S1: establishing a discrete horizontal plane included angle and a normal vector included angle in a three-dimensional space and response functions corresponding to different discrete distances, and establishing an acoustic coding library of an object;step S2: obtaining a surrounding environmental video in real time by using a visual input unit;step S3: obtaining object information and a category of a current environment by performing an object detection on each frame of a visual image based on the surrounding environmental video, and calculating a three-dimensional coordinate position of each object from the visual input unit through each frame of visual image information;step S4: establishing a three-dimensional sound field of the object according to the visual image information, the object information and the three-dimensional coordinate position obtained in combination with the acoustic coding library of the object; andstep S5: adjusting, for objects of different categories, the ...

Update method, system, end node and electronic device

An updating method including: acquiring, by an active update node, update information from a server; and acquiring or receiving, by a passive update node, the update information from the active update node through a local network. By using the update method and system, end node and electronic device provided in the present disclosure, an active update node of a plurality of end nodes in the same local network acquires update information from a server, and a passive update node acquires the update information from the active update node, thereby reducing the number of end nodes acquiring the update information from the server, and reducing the burden of the cloud.

Antimicrobial Gel Formulations

Disclosed herein are formulations comprising an N-halogenated or N,N-dihalogenated amine compound dispersed in a water-swellable polymer, wherein the compound is 90% stable for at least 30 days at about 25° C. Also disclosed are methods of treating or preventing infections caused by a bacterial, a microbial, a sporal, a fungal or a viral activity using such formulations.

ROTATION ANGLE MEASURING SYSTEM AND MACHINING SYSTEM COMPRISING THE SAME

A rotation angle measuring device includes a light source for generating a first light beam with a first polarization direction and a second light beam with a second polarization direction; a first beam splitter for splitting the first light beam and the second light beam to generate a third light beam and a fourth light beam; an image sensor for sensing a first interference pattern generated by the first and second light beams passing through a first displacement measurement module, and sensing a second interference pattern generated by the third and fourth light beams passing through a second displacement measurement module; and a processing unit for calculating two displacement values at two different positions on a measured object according to the first and second interference patterns, in order to further calculate a rotation angle of the rotation angle measuring device relative to the measured object along a first axis. 1. A rotation angle measuring device , comprising:a light source configured to generate a first light beam with a first polarization direction and a second light beam with a second polarization direction;a first beam splitter configured to split the first and second light beams to generate a third light beam with the first polarization direction and a fourth light beam with the second polarization direction;a first displacement measuring module configured to allow the first and second light beams to pass through a first side of the first displacement measuring module and to be further reflected to pass through a second side of the first displacement measuring module, wherein the first light beam is reflected by a first measuring surface of a measured object, and the second light beam is reflected inside the first displacement measuring module;a second displacement measuring module configured to allow the third and fourth light beam to pass through a first side of the second displacement measuring module and to be further reflected to pass ...

NETWORK MANAGEMENT METHOD AND APPARATUS

Embodiments of the present disclosure can provide network management methods and apparatuses, The method can comprise connecting by a first terminal device to a network through a connection mode; and acquiring management configuration information corresponding to the network system. 19-. (canceled)10. A network management method comprising:connecting by a first terminal device to a network system through a connection mode; andacquiring management configuration information corresponding to the network system.11. The method of claim 10 , wherein connecting claim 10 , by the first terminal device claim 10 , to the network system through the connection mode comprises:identifying, by the first terminal device, a second terminal device by scanning through the connection mode, to establish a connection to the second terminal device; andconnecting to the network system corresponding to the second terminal device.12. The method of claim 10 , further comprising:prior to connecting to the network system, sending, by the first terminal device, authentication information to a server that is connected to the second terminal device for authentication.13. (canceled)14. The method of claim 12 , wherein sending claim 12 , by the first terminal device claim 12 , authentication information to the server for authentication comprises:determining device information of the first terminal device according to encryption information, wherein the encryption information comprises at least one of a certificate or a key; andsending the device information of the first terminal device to the server for authentication via the second terminal device connected with the server.15. The method of claim 10 , further comprising:sending, by the first terminal device, a data request to a server for subscribing to service information according to the data request.16. The method of claim 10 , wherein data between the first terminal device and the server is transferred through a gateway device.17. The method of ...

Method for Efficiently Preparing Ferrate Based on Nascent Interfacial Activity

A method for efficiently preparing ferrate based on nascent state interfacial activity. The method is as follows: (a) preparing nascent iron solution; (b) adding an oxidizing agent to the iron solution of step (a); (c) adding alkali solution or alkali particles to the mixed solution of step (b), mixing by stirring, and carrying out solid-liquid separation; (d) adding a stabilizing agent to the liquid separated out in step (c), and thus obtaining ferrate solution. The yield is 78-98%. The prepared ferrate solution is stable and can be stored for 3-15 days. 1. A high efficiency preparation method for ferrate based on activity in nascent state interface , characterized in that , the high efficiency preparation method for ferrate based on activity in nascent state interface comprises the steps of:(a) adding solid iron salt to a first alkaline solution with a pH of 5˜9 for hydrolysis and producing an iron solution in nascent state with an equivalent concentration of iron of 0.0001˜1 mol/L;(b) measuring and obtaining 5˜100 mL of the iron solution in nascent state from step (a), adding an oxidizing agent based on a molar ratio of the iron in nascent state and the oxidizing agent at 1:0.1˜20 and mixing the oxidizing agent with the iron solution in nascent state to obtain a mixture;(c) under the condition of 5° C.˜60° C., adding 5˜100 mL second alkaline solution or 0.2˜70 g alkaline granules to the mixture from the step (b), wherein the second alkaline solution has a concentration of 0.1˜16 mol/L; then stirring and mixing for 0.1˜30 min to form an intermediate solution; allowing the intermediate solution to turn purplish black color completely and then process solid-liquid separation by centrifugation or filtration to obtain a liquid; and(d) adding stabilizing agent based on a molar ratio of the equivalent concentration of iron in the liquid from the step (c) and the stabilizing agent of 1:0.1˜10 to obtain a ferrate solution.2. The high efficiency preparation method for ...

PRIMARY CARBOXAMIDES AS BTK INHIBITORS

The invention provides compounds of Formula (I) 2. The compound according to claim 1 , wherein Y is CR′ and R′ of Y is H claim 1 , optionally substituted ethenyl claim 1 , optionally substituted ethyl claim 1 , optionally substituted methyl claim 1 , optionally substituted 2 claim 1 ,3-dihydrobenzofuranyl claim 1 , optionally substituted 1 claim 1 ,4-dioxanyl claim 1 , optionally substituted 3 claim 1 ,4-dihydro-2H-benzo[b][1 claim 1 ,4]oxazinyl claim 1 , optionally substituted 6 claim 1 ,7-dihydro-4H-pyrazolo[5 claim 1 ,1-c][1 claim 1 ,4]oxazinyl claim 1 , optionally substituted chromanyl claim 1 , optionally substituted cyclohexenyl claim 1 , optionally substituted cyclopropyl claim 1 , optionally substituted tetrahydrofuranyl claim 1 , optionally substituted isochromanyl claim 1 , optionally substituted 1 claim 1 ,2 claim 1 ,3 claim 1 ,4-tetrahydro-isoquinolinyl claim 1 , optionally substituted isoxazolyl claim 1 , optionally substituted morpholinyl claim 1 , optionally substituted oxetanyl claim 1 , optionally substituted phenyl claim 1 , optionally substituted piperidinyl claim 1 , optionally substituted piperazinyl claim 1 , optionally substituted 3 claim 1 ,6-dihydro-2H-pyranyl claim 1 , optionally substituted pyrano[4 claim 1 ,3-b]pyridinyl claim 1 , optionally substituted pyrazolyl claim 1 , optionally substituted pyridinyl claim 1 , optionally substituted 3H-pyridin-1-one claim 1 , optionally substituted 1 claim 1 ,2 claim 1 ,3 claim 1 ,6-tetrahydropyridinyl claim 1 , optionally substituted pyrimidinyl claim 1 , optionally substituted pyrrolidinyl claim 1 , optionally substituted 2 claim 1 ,5-dihydropyrrolyl claim 1 , optionally substituted tetrahydropyranyl or optionally substituted tetrahydro-2H-thiopyranyl.3. The compound according to wherein R′ is H or R′ is optionally substituted by one or more substituents independently selected from the group consisting of CN claim 2 , OH claim 2 , ═O claim 2 , halogen claim 2 , (C-C)alkyl claim 2 , (C-C)alkoxy ...

THREE-DIMENSIONAL POLYMERIC STRAND NETTING, DIES, AND METHODS OF MAKING THE SAME

Method and extrusion die () for producing a three-dimensional polymeric strand netting, wherein a plurality of the polymeric strands () are periodically joined together in a regular pattern at bond regions throughout the array, wherein a majority of the polymeric strands () are periodically bonded to at least two (three, four, five, six, or more) adjacent polymeric strands, and wherein no polymeric strands are continuously bonded to a polymeric strand. Three-dimensional polymeric strand netting described herein have a variety of uses, including wound care, tapes, filtration, absorbent articles, pest control articles, geotextile applications, water/vapor management in clothing, reinforcement for nonwoven articles, self bulking articles, floor coverings, grip supports, athletic articles, and pattern coated adhesives. 1. A three-dimensional polymeric strand netting , wherein a plurality of the polymeric strands are periodically joined together in a regular pattern at bond regions throughout the netting , wherein at least some of the polymeric strands are periodically bonded to at least three adjacent polymeric strands , and wherein no polymeric strands are continuously bonded to another polymeric strand.2. The three-dimensional polymeric strand netting of claim 1 , wherein the three-dimensional network of polymeric strands has a thickness up to 750 micrometers.3. The three-dimensional polymeric strand netting of having a basis weight in a range from 5 g/mto 400 g/mor a range from 0.5 g/mto 40 g/m.4. The three-dimensional polymeric strand netting of further comprising third strands disposed between at least some of the alternating first and second strands.5. The three-dimensional polymeric strand netting of claim 1 , wherein at least a plurality of the polymeric strands have a core of a first polymeric material and a sheath of a second claim 1 , different polymeric material.6. The three-dimensional polymeric strand netting of claim 1 , wherein at least some of strands ...

NETTING, ARRAYS, AND DIES, AND METHODS OF MAKING THE SAME

Nettings and arrays comprising polymeric strands, including dies () and methods to make the same. Nettings and arrays of polymeric strands () described herein have a variety of uses, including wound care, tapes, filtration, absorbent articles, pest control articles, geotextile applications, water/vapor management in clothing, reinforcement for non-woven articles, self bulking articles, floor coverings, grip supports, athletic articles, and pattern-coated adhesives. 1. A netting comprising an array of polymeric strands periodically joined together at bond regions throughout the array , but do not substantially cross over each other , wherein the netting has a thickness up to 750 micrometers.2. An article comprising two nettings of with a ribbon region disposed there between.3. An article comprising the netting of disposed between two ribbon regions.4. A method of making the netting of claim 1 , the method comprising one of Method I or Method II:Method Iproviding an extrusion die comprising a plurality of shims positioned adjacent to one another, the shims together defining a cavity, the extrusion die having a plurality of first dispensing orifices in fluid communication with the cavity and a plurality of second dispensing orifices in fluid communication with the cavity, such that the first and second dispensing orifices are alternated; anddispensing first polymeric strands from the first dispensing orifices at a first strand speed while simultaneously dispensing second polymeric strands from the second dispensing orifices at a second strand speed, wherein the first strand speed is at least 2 times the second strand speed to provide the netting; orMethod IIproviding an extrusion die comprising a plurality of shims positioned adjacent to one another, the shims together defining a first cavity and a second cavity, the extrusion die having a plurality of first dispensing orifices in fluid communication with the first cavity and having a plurality of second dispensing ...

SYSTEM AND METHOD FOR IMAGE RECONSTRUCTION

The present disclosure relates to a system, method and storage medium for generating an image. At least one processor, when executing instructions, may perform one or more of the following operations. When raw data is received, a plurality of iterations may be implemented. During each iteration, a first voxel value relating to a first voxel in an image is calculated; at least a portion of a second voxel may be continuously changed with respect to at least a portion of the first voxel value; the image may be transformed to a projection domain to generate an estimated projection based on the first voxel value and the second voxel value; a projection error may be obtained based on the estimated projection and the raw data; and the image may be corrected or updated based on the projection error. 1. A method comprising:receiving raw data relating to a subject; calculating a first voxel value relating to a first voxel and a second voxel value relating to a second voxel at each successive iteration based on an image obtained from a prior iteration, wherein at least a portion of the second voxel value is continuous with respect to at least a portion of the first voxel value;', 'transforming the image to a projection domain to generate an estimated projection based on the first voxel value and the second voxel value;', 'generating a projection error based on the estimated projection and the raw data; and', 'generating an image based on the projection error to be used in a next iteration; and, 'during each of a plurality of iterations,'}obtaining, based on the plurality of iterations, a reconstructed image.2. The method of claim 1 , wherein the second voxel adjoins the first voxel.3. The method of claim 1 , wherein the first voxel value relating to at least a portion of the first voxel comprises a distribution according to a first function.4. The method of claim 3 , wherein the first function is a linear function.5. The method of claim 3 , wherein the second voxel value ...