03-07-2014 дата публикации
Номер: US20140186378A1
Принадлежит:
This invention relates to immunogenic compounds which serve as ligands for NKT (natural killer T) cells and to methods of use thereof in modulating immune responses. 140-. (canceled)42. The method according to claim 41 , wherein Rand X of the structure of formula (17) are saturated alkyl groups containing from 1 to 30 carbons.43. The method according to claim 42 , wherein Rand X of the structure of formula (17) are saturated alkyl groups containing from 5 to 25 carbons.44. The method according to claim 43 , wherein Rof the structure of formula (17) is H.46. The method according to claim 43 , wherein Rof the structure of formula (17) is halogen.48. The method according to claim 43 , wherein Rof the structure of formula (17) is alkoxy.50. The method according to claim 43 , wherein Rof the structure of formula (17) is CF.52. The method according to claim 43 , wherein Rof the structure of formula (17) is phenyl.55. The method according to claim 54 , wherein Rand X are saturated alkyl groups containing from 1 to 30 carbons.56. The method according to claim 55 , wherein Rand X are substituted alkyl groups containing from 2 to 10 carbons.57. The method according to claim 56 , wherein Ris H. This Application is a continuation of U.S. patent application Ser. No. 13/420,738, filed Mar. 15, 2012, now U.S. Pat. No. 8,586,051, issued Nov. 19, 2013, which is a continuation of U.S. patent application Ser. No. 12/958,996, filed Dec. 2, 2010, now U.S. Pat. No. 8,163,290, issued Apr. 24, 2012, which is a continuation of U.S. patent application Ser. No. 11/735,313, filed Apr. 13, 2007, now U.S. Pat. No. 7,923,013, issued Apr. 12, 2011, which is a continuation-in-part of U.S. patent application Ser. No. 11/317,900, filed Dec. 27, 2005, now U.S. Pat. No. 7,534,434, issued May 19, 2009, which claims the benefit of U.S. Provisional Patent Application Ser. No. 60/639,408, filed Dec. 28, 2004, each of which is incorporated by reference herein in its entirety.This invention was made in whole ...
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