STAPLER FOR MUCOSECTOMY

A head for a stapler used during a mucosectomy is disclosed that includes an external body, an internal body, an anvil, and a blade. The internal body includes a central hole into which a rod is slidingly inserted. One or more annular grooves are formed on a lateral surface of the rod, and are intended to receive a portion of mucosa which is included in a purse string suture as the mucosa is tied around the rod. By retracting the rod in the central hole of the internal body, the mucosa to be removed is carried into the internal body. 18-. (canceled)9. A surgical fastener applying apparatus , comprising:a head assembly including a body;an anvil rod configured and dimensioned for slidable insertion into the body of the head assembly; andan anvil attached to a distal end of the anvil rod, wherein the anvil rod includes three annular grooves formed in an outer surface thereof arranged in perpendicular relation to a longitudinal axis of the anvil rod, the grooves being spaced from one another along the longitudinal axis of the anvil rod such that a portion of the outer surface of the anvil rod is positioned between adjacent grooves, the grooves being arranged at varying distances from the anvil, and being configured and dimensioned to selectively receive a portion of mucosa to be tied around the anvil rod in a purse string suture such that varying amounts of mucosa can be drawn into the body of the head assembly during approximation of the head assembly and the anvil dependent upon the groove to which the mucosa is secured.10. The surgical fastener applying apparatus according to claim 9 , wherein one of the grooves is spaced 10 mm from the anvil claim 9 , one of the grooves is spaced 20 mm from the anvil claim 9 , and one of the grooves is spaced 30 mm from the anvil.11. The surgical fastener applying apparatus according to claim 9 , wherein each groove defines a depth between 0.5 mm and 3 mm.12. The surgical fastener applying apparatus according to claim 11 , wherein ...

Method and System for Recovering and Preparing Glacial Water

Methods and systems for grouping, recovering, and processing ice obtained from an ice source, i.e., a glacier, ice sheet, ice cap, etc., are described herein. In particular, the ice obtained from the ice source is separated and grouped according to common unique properties and processed as a beverage for consumption having the same unique properties.

ANOSCOPE FOR ANO-RECTAL DIAGNOSTIC AND SURGERY

A composite anoscope for ano-rectal diagnostic and surgery, wherein the anoscope () also comprises an internal component (), to be inserted therein, and a suitably shorter external component (), ending with a conic frustum mantle (), wherein the anoscope () is to be inserted. The three components () are all conic frustum shaped hollow bodies having circular cross-section. The internal component (), when inserted in the anoscope (), forms therewith a single body having a compact and smooth external surface and an ogival tip. The external component () is provided close to its mouth with slotted wings (), to be fixed to the perianal skin for securing the whole composite anoscope during the diagnostic and surgical operations. 17-. (canceled)8. A surgical device comprising:an anoscope including a plurality of distally extending protrusions; andan internal component adapted to be inserted into the anoscope, the internal component including a plurality of grooves corresponding in configuration and dimensions to the protrusions, whereby the protrusions are positionable within the grooves, such that the device defines a smooth external surface upon insertion of the internal component into the anoscope to a maximum extent permitted by the anoscope.9. The surgical device of claim 8 , wherein the internal component further includes a mantle claim 8 , the protrusions extending distally from the mantle.10. The surgical device of claim 8 , wherein the anoscope and the internal component each have a frustum conic configuration claim 8 , whereby the device defines an ogival distal tip upon insertion of the internal component into the anoscope to the maximum extent permitted by the anoscope.11. The surgical device of further comprising an external component claim 8 , the anoscope being configured and dimensioned for insertion into the external component.12. The surgical device of claim 8 , wherein the anoscope and the internal component include distalmost surfaces existing in a ...

BALANCING DEVICE, PARTICULARLY FOR TURBOCOMPRESSORS, AND CORRESPONDING METHOD

A balancing device, particularly for turbocompressors, comprising a base structure which supports elastically a supporting structure which has a flange for supporting a receptacle of a rotating element and a rotating element, wherein the rotating element can move with a rotary motion about its own rotation axis; actuation elements being adapted to actuate lever elements along a substantially radial direction; the lever elements being adapted to generate a force for fixing the receptacle of the rotating element to the supporting flange in a direction that is substantially parallel to the rotation axis. 1. A balancing device , particularly for turbocompressors , comprising a base structure which supports elastically a supporting structure which has a flange for supporting a receptacle of a rotating element and a rotating element , said rotating element being movable with a rotary motion about its own rotation axis , further comprising actuation means adapted to actuate lever means along a substantially radial direction , said lever means being adapted to generate a force for fixing said receptacle to said flange in a direction which is substantially parallel to said rotation axis.2. The balancing device according to claim 1 , wherein elastic elements are comprised between said actuation means and said lever means claim 1 , act in a substantially radial direction and are adapted to uncouple mechanically said actuation means from said lever means.3. The balancing device according to claim 2 , wherein in said lever means a power arm to which the force of said actuation means is applied claim 2 , in said substantially radial direction claim 2 , is longer than the resistance arm that generates the force for fixing in said direction which is substantially parallel to said rotation axis.4. The balancing device according to claim 1 , wherein said lever means are adapted to perform a translational movement in a radial direction and to rotate on a plane that passes through said ...

Lifting device, particularly for lifting wheels and the like, for wheel balancing and tire moving machines

A lifting device, particularly for lifting wheels of vehicles and the like, for wheel balancing and tire removing machines, comprising a scissor-like frame, which is interposed between at least two flat and mutually parallel elements for their mutual translational motion as a consequence of the action of motor means functionally associated with the scissor-like frame, the lifting device further comprising a cam-type profiled element, which can be engaged functionally with the motor for dynamic and static balancing between the thrust force generated by the motor and the contrast force of the scissor-like frame in addition to the weight of the object to be lifted, which is arranged on one of the two flat and parallel elements, in all the operating positions of the lifting device. 1. A lifting device , particularly for lifting wheels of vehicles and the like , for wheel balancing and tire removing machines , comprisinga scissor-like frame,at least two flat and mutually parallel elements comprising a lower base element and a resting surface element for supporting a weight thereon, said scissor-like frame being interposed between said at least two flat and mutually parallel elements,at least one pneumatic actuator functionally associated with said scissor-like frame, said pneumatic actuator comprising a cylinder and a movable piston which is movably arranged inside said cylinder,means for supplying compressed air to said cylinder of said pneumatic actuator,a first fixed cam profile,a second cam profile of said scissor-like frame,at least one bearing connected with said movable piston of said pneumatic actuator and arranged to slidably engage simultaneously said first fixed cam profile and said second cam profile for selective opening or closing of said scissor-like frame and for providing a mutual translational motion of said at least two flat and mutually parallel elements,said pneumatic actuator operating such that a pressure of air contained inside said cylinder of ...

Device For A Nurse Call System

The present invention relates to a device for a nurse call system, wherein the device comprises: a core nurse call functionality; and an embedded viewer adapted to provide access to at least one system external of the nurse call system in order to provide the device with additional functionality. The present invention also relates to a nurse call system and a corresponding method. 1. A device for a nurse call system , wherein the device comprises:a display;a core nurse call functionality configured to present a user interface for nurse call system operation at the display; andan embedded viewer adapted to provide access to at least one system external of the nurse call system in order to provide the device with additional functionality; a) access the at least one system via a network communicatively coupled to the nurse call system;', 'b) retrieve content from the at least one system; and', 'c) cause the content to be presented at the display., 'the embedded viewer being configured to2. A device according to claim 1 , wherein the core nurse call functionality has precedence over the embedded viewer.3. A device according to claim 1 , wherein the embedded viewer is restricted with respect to how much capacity of the device that the embedded viewer can use.4. A device according to claim 1 , wherein the embedded viewer in operation runs in a restricted environment.5. A device according to claim 1 , wherein the embedded viewer in operation is monitored through application performance management.6. A device according to claim 1 , wherein the display is configured to interchangeably show the user interface for nurse call system operation and the content retrieved by the embedded viewer.7. A device according to claim 6 , wherein the display is further configured to show a bar comprising navigational touch points allowing a user to switch between the user interface of the core nurse call functionality and the content retrieved by the embedded viewer.8. A device according to ...

STAPLER FOR MUCOSECTOMY

The head of a stapler for mucosectomy comprises an external goblet-shaped body () wherein an internal goblet-shaped body () is concentrically and slidingly located, at the edge of which a circular blade () is fixed. The internal goblet-shaped body () is provided with a central hole () wherein a rod () is slidingly inserted, at the end () of which an anvil () is fixed. One or more annular grooves (), which are parallel and suitably spaced one from the other, are formed on the lateral surface of the rod () perpendicularly to the axis thereof. Said grooves () are intended to receive a portion of mucosa (a) which is included in a purse string suture as the mucosa is tied around the rod (). By retracting the rod () in the central hole () of the stem (a) of the Internal goblet-shaped body () the mucosa to be removed is carried into the internal goblet-shaped body (). The anvil () and the circular blade () are moved closer one to the other, by suitable means, in order to cut the tissues when the stapler is in a closed position. 18-. (canceled)9. A surgical fastener applying apparatus , comprising:a compression device including first and second components;a head assembly supporting the second component of the compression device;a rod moveable through the head assembly, the rod supporting the first component and defining a plurality of grooves in an outer surface thereof, the plurality of grooves being axially spaced along the rod, the first and second components of the compression device configured to be coupled together to capture tissue therebetween, each of the grooves providing a fixing position for a purse-string suture on the rod to prevent sliding movement of the suture along the rod.10. The surgical fastener applying apparatus of claim 9 , wherein each of the plurality of grooves extends in perpendicular relation to a longitudinal axis of the rod.11. The surgical fastener applying apparatus of claim 9 , wherein each of the plurality of grooves is annular in ...

Gender specific synthetic nutritional compositions and nutritional systems comprising them

Gender specific synthetic nutritional compositions for infants up to 1 month of age, wherein the leucine and/or threonine and/or tyrosine content is adapted based on that found in HM produced for an infant of the same gender and age, and nutritional systems comprising them.

Gender specific synthetic nutritional compositions and nutritional systems comprising them

Gender specific synthetic nutritional compositions for infants up to 1 month of age wherein, the caseins content is adapted based on that found in HM produced for an infant of the same gender and age, and nutritional systems comprising them.

High resolution virtual wheel speed sensor

A method for producing high resolution virtual wheel speed sensor data includes simultaneously collecting wheel speed sensor (WSS) data from multiple wheel speed sensors each sensing rotation of one of multiple wheels of an automobile vehicle. A camera image is generated of a vehicle environment from at least one camera mounted in the automobile vehicle. An optical flow program is applied to discretize the camera image in pixels. Multiple distance intervals are overlayed onto the discretized camera image each representing a vehicle distance traveled defining a resolution of each of the multiple wheel speed sensors. A probability distribution function is created predicting a distance traveled for a next WSS output.

Methods of Inhibiting Neutrophil Recruitment to the Gingival Crevice

Methods of increasing proteins that reduce signals associated with neutrophil recruitment and reducing proteins that induce neutrophil recruitment within an individuals gingival crevice are disclosed. The methods comprise applying to the individuals oral cavity in an amount effective to increase proteins that reduce signals associated with neutrophil recruitment and reduce proteins that induce neutrophil recruitment within an individuals gingival crevice, an oral care composition comprising: zinc phosphate, stannous fluoride and optionally, an organic acid buffer system.

SPIRAL-WOUND PTFE GASKET AND METHODS OF MANUFACTURE

A method of manufacturing a spiral-wound PTFE gasket includes winding a laminated PTFE tape () around a shaft () that has an outer diameter that coincides with the gasket inner diameter to create a PTFE cylinder () having an outer diameter that coincides with the gasket outer diameter; sintering the PTFE cylinder (); and removing a radial segment of the PTFE cylinder () to form the gasket (), the radial segment having a thickness that coincides with the gasket thickness. 1. A method of manufacturing a gasket having a gasket thickness , a gasket inner diameter , and a gasket outer diameter , the method comprising:winding a laminated PTFE tape around a shaft that has an outer diameter that coincides with the gasket inner diameter to create a PTFE cylinder having an outer diameter that coincides with the gasket outer diameter;sintering the PTFE cylinder; andremoving a radial segment of the PTFE cylinder to form the gasket, the radial segment having a thickness that coincides with the gasket thickness.2. The method of claim 1 , further comprising drying the PTFE cylinder.3. The method of claim 1 , further comprising drying the laminated PTFE tape.4. The method of claim 1 , further comprising compressing the PTFE cylinder in a mold.5. The method of claim 1 , further comprising winding a polymer tape around the shaft.6. The method of claim 1 , further comprising stretching the laminated PTFE tape. The method of claim 1 , further comprising laminating a PTFE billet to form the laminated PTFE tape.8. The method of claim 1 , wherein the laminated PTFE tape is a monoaxially expanded laminated PTFE tape claim 1 , a biaxially expanded laminated PTFE tape claim 1 , or a multiaxially expanded laminated PTFE tape.9. The method of claim 1 , wherein the laminated PTFE tape includes a filler.10. The method of claim 9 , wherein the filler is a mineral filler.11. The method of claim 5 , wherein the polymer tape is an impermeable polymer tape.12. The method of claim 5 , wherein the ...

Semi-autonomous reversing of a follower vehicle

Systems and methods for reversing a semi-autonomous follower vehicle involve obtaining a speed of a leader vehicle in front of and unattached to the follower vehicle that is reversing. A method includes estimating a path of the leader vehicle and determining a path for the follower vehicle based on the path of the leader vehicle. A longitudinal movement of the follower vehicle is controlled based on the speed of the leader vehicle and a lateral movement of the follower vehicle is controlled based on the path for the follower vehicle.

STAPLER FOR MUCOSECTOMY

The head of a stapler for mucosectomy comprises an external goblet-shaped body () wherein an internal goblet-shaped body () is concentrically and slidingly located, at the edge of which a circular blade () is fixed. The internal goblet-shaped body () is provided with a central hole () wherein a rod () is slidingly inserted, at the end () of which an anvil (′) is fixed. One or more annular grooves (), which are parallel and suitably spaced one from the other, are formed on the lateral surface of the rod () perpendicularly to the axis thereof. Said grooves () are intended to receive a portion of mucosa () which is included in a purse string suture as the mucosa is tied around the rod (). By retracting the rod () in the central hole () of the stem () of the internal goblet-shaped body () the mucosa to be removed is carried into the internal goblet-shaped body (). The anvil (′) and the circular blade () are moved closer one to the other, by suitable means, in order to cut the tissues when the stapler is in a closed position. 18-. (canceled)9. A method of performing a surgical procedure , comprising:securing a flexible member to a section of target tissue;securing the flexible member to a groove formed in a portion of an anvil member;drawing the portion of the anvil member to which the flexible member is secured into a head assembly of a surgical fastener applying apparatus to draw a portion of the target tissue into the head assembly; andfiring the surgical fastener applying apparatus to secure one or more surgical fasteners to the target tissue.10. The method of claim 9 , wherein securing the flexible member includes securing the flexible member to a rod of the anvil member claim 9 , the groove being formed in the rod.11. The method of claim 10 , wherein securing the flexible member includes securing the flexible member directly to the rod.12. The method of claim 9 , further comprising inserting the anvil member into an opening in a patient.13. The method of claim 10 , ...

STAPLER FOR MUCOSECTOMY

The head of a stapler for mucosectomy comprises an external goblet-shaped body () wherein an internal goblet-shaped body () is concentrically and slidingly located, at the edge of which a circular blade () is fixed. The internal goblet-shaped body () is provided with a central hole () wherein a rod () is slidingly inserted, at the end () of which an anvil () is fixed. One or more annular grooves (), which are parallel and suitably spaced one from the other, are formed on the lateral surface of the rod () perpendicularly to the axis thereof. Said grooves () are intended to receive a portion of mucosa () which is included in a purse string suture as the mucosa is tied around the rod (). By retracting the rod () in the central hole () of the stem () of the Internal goblet-shaped body () the mucosa to be removed is carried into the internal goblet-shaped body (). The anvil () and the circular blade () are moved closer one to the other, by suitable means, in order to cut the tissues when the stapler is in a closed position. 1. A method of performing a surgical procedure , comprising:securing a suture to a section of target tissue;securing the suture to a rod of an anvil member of a surgical apparatus; anddrawing the anvil member into a head assembly of the surgical apparatus such that a first component supported about the rod is coupled to a second component arranged on the head assembly with a portion of the section of target tissue disposed between the first and second components.2. The method according to claim 1 , wherein securing the suture to the rod includes securing the suture to a groove formed along the rod.3. The method according to claim 2 , wherein securing the suture to the groove includes selecting the groove from a plurality of longitudinally spaced grooves formed along the rod based on the volume of tissue to be removed.4. The method according to claim 3 , wherein selecting the groove from the plurality of longitudinally spaced grooves includes selecting ...

Anoscope for Ano-Rectal Diagnostic and Surgery

A composite anoscope for ano-rectal diagnostic and surgery, wherein the anoscope ( 2 ) also comprises an internal component ( 1 ), to be inserted therein, and a suitably shorter external component ( 3 ), ending with a conic frustum mantle ( 18 ), wherein the anoscope ( 2 ) is to be inserted. The three components ( 1, 2, 3 ) are all conic frustum shaped hollow bodies having circular cross-section. The internal component ( 1 ), when inserted in the anoscope ( 2 ), forms therewith a single body having a compact and smooth external surface and an ogival tip. The external component ( 3 ) is provided close to its mouth with slotted wings ( 19, 20 ), to be fixed to the perianal skin for securing the whole composite anoscope during the diagnostic and surgical operations.

Axial fan

An axial fan comprises a hub and a plurality of blades extending from the hub; wherein each blade comprises a main blade portion and a secondary blade portion and the secondary blade portion has a leading edge adjacent to a leading edge of the main blade portion and forms a flap for the main blade portion; wherein a fluid passage is defined between the leading edge of the main blade portion and the leading edge of the secondary blade portion; wherein the main blade portion has a main chord and the secondary blade portion has a secondary chord; and wherein the main chord and the secondary chord form a relative attack angle comprised between 5° and 35°.

DEVICE AND METHOD FOR MEASURING THE CHARACTERISTIC ANGLES AND DIMENSIONS OF WHEELS, STEERING SYSTEM AND CHASSIS OF VEHICLES IN GENERAL

A device for measuring the characteristic angles and dimensions of wheels, steering system and chassis of vehicles in general, comprising a plurality of three-dimensional optical readers which are functionally connected to a computer and can be arranged peripherally to a vehicle whose dimensions and characteristic angles of wheels, steering system and chassis are to be measured in such a manner that each one frames at least one wheel of the vehicle for the three-dimensional acquisition of an image of the wheel, each three-dimensional optical reader being provided with at least one fixed target for the setting and calibration of the measurement device, at least one camera of each three-dimensional optical reader being arranged in such a manner as to frame clearly and directly at least one fixed target of another three-dimensional optical reader for the setting and calibration of the measurement device by three-dimensional acquisitions of the fixed targets. 115-. (canceled)16. A device for measuring characteristic angles and dimensions of wheels , steering system and chassis of vehicles in general , comprising a plurality of three-dimensional optical readers which are functionally connected to a computer and can be arranged peripherally to a vehicle whose dimensions and characteristic angles of wheels , steering system and chassis are to be measured in such a manner that each one frames at least one wheel of said vehicle for the three-dimensional acquisition of an image of said at least one wheel , each one of said three-dimensional optical readers being provided with at least one fixed target for the setting and calibration of said measurement device , wherein at least one camera of each one of said three-dimensional optical readers is arranged in such a manner as to frame directly at least one fixed target of another one of said three-dimensional optical readers for the setting and calibration of said measurement device by three-dimensional acquisitions of said ...

DOUBLE-SHOULDER, DOUBLE-RAIL SERRATED METAL GASKET

An isolation gasket that includes a metal core () defining an inner serrated annular section () that is radially spaced from an outer serrated annular section (); and an annular groove () formed between the inner and outer serrated annular sections; and a first material () accommodated in the annular groove (). In certain embodiments, a second material () is coupled to the inner serrated annular section (); and a third material () is coupled to the outer serrated annular section (). In one embodiment, the second material () has a first thickness () and the third material () has a second thickness () that is less than the first thickness (). In one embodiment, the metal core () defines a first inner diameter () and the second material defines a second inner diameter () that is less than the first inner diameter (). 1. An isolation gasket , comprising: an inner serrated annular section that is radially spaced from an outer serrated annular section; and', 'an annular groove formed between the inner and outer serrated annular sections;, 'a metal core defininga first material accommodated in the annular groove;a second material coupled to the inner serrated annular section; anda third material coupled to the outer serrated annular section;wherein the second material has a first thickness; andwherein the third material has a second thickness that is less than the first thickness.2. The isolation gasket of claim 1 , wherein the ratio of the first thickness to the second thickness is between about 4.0 and about 1.5.3. The isolation gasket of claim 1 , wherein the ratio of the first thickness to the second thickness is about 2.0.4. The isolation gasket of claim 1 ,wherein the second material forms a first annular ring and has an outer surface defining an outer diameter;wherein the third material forms a second annular ring having an inner surface that defines an inner diameter and an upper surface perpendicular to the inner surface; andwherein a shoulder is formed between ...

Anoscope for Ano-Rectal Diagnostic and Surgery

A composite anoscope for ano-rectal diagnostic and surgery, wherein the anoscope () also comprises an internal component (), to be inserted therein, and a suitably shorter external component (), ending with a conic frustum mantle (), wherein the anoscope () is to be inserted. The three components () are all conic frustum shaped hollow bodies having circular cross-section. The internal component (), when inserted in the anoscope (), forms therewith a single body having a compact and smooth external surface and an ogival tip. The external component () is provided close to its mouth with slotted wings (), to be fixed to the perianal skin for securing the whole composite anoscope during the diagnostic and surgical operations. 17-. (canceled)8. A method of performing a surgical procedure comprising:assembling a surgical device by inserting an internal component into an anoscope such that a plurality of grooves defined by the internal component receive a corresponding plurality of protrusions extending distally from a body of the anoscope, whereby the surgical device is provided with a smooth external surface; andinserting the surgical device into an internal worksite within a patient.9. The method of claim 8 , wherein inserting the surgical device into the internal worksite includes inserting the surgical device into the patient's anal canal.10. The method of claim 8 , wherein assembling the surgical device further includes inserting the internal component and the anoscope into an external component.11. The method of claim 10 , further including fixing the external component to the patient's tissue.12. The method of claim 11 , wherein fixing the external component to the patient's tissue includes suturing the external component to the patient's tissue.13. The method of claim 12 , wherein suturing the external component to the patient's tissue includes passing a suture through openings formed in wings extending radially outward from a body of the external component.14. ...

WHEEL BALANCING DEVICE

A wheel balancing device, comprising a rotation shaft on which a wheel can be mounted and elements for fixing the wheel to the rotation shaft and further comprising:

METHOD AND MACHINE FOR BALANCING A VEHICLE WHEEL

A method for balancing a vehicle wheel includes mounting a wheel to be balanced on a rotating shaft of a machine computerized for measuring imbalances, and selecting an optimum commercial balancing weight which, when positioned on a correction plane, minimizes residual imbalance on reference planes of the wheel where the balancing tolerance is considered. One compares the residual imbalance value at the reference planes with the prescribed balancing tolerance after subtracting a vector of the static imbalance generated by the optimum balancing weight. An indicator device is activated to indicate on the wheel the optimum axial position of a correction plane for a balancing weight where the residual imbalance at the reference planes is within tolerance. 1. A method for balancing a vehicle wheel , comprising the steps ofmounting a wheel to be balanced on a rotating shaft of a machine that comprises a computerized system for measuring imbalances, a system for measuring the distance and the diameter of the possible correction regions, an indicator device that is configured to indicate one or more correction positions on said wheel;determining the axial position of the correction plane where a static balancing weight is to be located so as to minimize the imbalance on the reference planes of the wheel, where the residual imbalance is to be measured;selecting an optimum commercial balancing weight which, when positioned on said correction plane, minimizes the residual imbalance on the reference planes where the balancing tolerance is considered;comparing the residual imbalance value at the reference planes with the prescribed balancing tolerance after subtracting the vector of the static imbalance generated by the optimum balancing weight obtained above;signaling to the operator the possibility to perform balancing with a single balancing weight if the residual imbalance at the reference planes is within tolerance;activating said indicator device in order to indicate on ...

Synthetic nutritional compositions tailored for infants of specific ages, and nutritional systems comprising them

Synthetic nutritional compositions tailored for infants of specific ages comprising cholesterol in concentrations reflecting those found in human milk produced for infants of the same specific ages, and nutritional systems comprising them.

PURINE DERIVATIVE FOR USE IN THE TREATMENT OR PREVENTION OF DISEASES CAUSED BY A NONSENSE MUTATION

The present disclosure relates to 2,6-diaminopurine (DAP) for use in the treatment of a disease caused by a nonsense mutation in a gene, leading to the premature insertion of a UGA stop codon. 1. A method of treating a disease due to a nonsense mutation in a gene leading to the premature introduction of a UGA stop codon , comprising administering to a subject in need thereof a therapeutically effective amount of 2 ,6-diaminopurine (DAP).2. The method according to claim 1 , wherein said disease is selected from among cystic fibrosis due to said nonsense mutation claim 1 , muscular dystrophies due to said nonsense mutation claim 1 , beta-thalassemia due to said nonsense mutation claim 1 , retinitis pigmentosa due to said nonsense mutation claim 1 , mucopolysaccharidosis due to said nonsense mutation claim 1 , spinal muscular atrophy due to said nonsense mutation.3. The method according to claim 1 , wherein said DAP is administered to a subject in combination with a compound having a readthrough activity selected from the group consisting of 6-amino-5-nitro-4-(α-D-ribofuranosylamino)-pyrimidine claim 1 , 6-amino-5-nitro-4-(β-D-ribofuranosylamino)-pyrimidine claim 1 , ataluren claim 1 , gentamicin claim 1 , geneticin claim 1 , paromomycin and paromomycin derivatives such as NB30; NB54; NB74; NB84 claim 1 , amikacin claim 1 , tobramycin claim 1 , pyramycine and pyramycine derivatives such as TC001; TC003; TC007; TC032 claim 1 , kanamycin and kanamycin derivatives such as JL022; JL023 claim 1 , amlexanox claim 1 , RTC 13 (Lavin claim 1 , 2013) claim 1 , RTC 14 (Lavin claim 1 , 2013) claim 1 , 3-(2-4E(1 claim 1 ,1 dimethyl propyl)-phenoxy-acetylamino)-benzoic acid claim 1 , 3-(2-(4-isopropyl-3-methyl-phenoxy)-acetylamino)-benzoic acid claim 1 , negamycin claim 1 , tylosin claim 1 , josamycine claim 1 , spiramycin claim 1 , and 3-(2-(4-tert-butyl-phenoxy)-acetylamino)-benzoic acid.4. A pharmaceutical composition comprising DAP and a pharmaceutically-acceptable excipient for ...

Oral Care Compositions and Methods for Anti-Attachment Polymers and Coatings

Antimicrobial compositions and methods for depositing or coating the antimicrobial or antibacterial compositions on a substrate to prevent microbial adhesion are provided. The antimicrobial composition may include a cationic polymer having a poly-allylamine backbone. A portion of the poly-allylamine backbone may be functionalized with at least one of a guanidine functional group and a biguanide functional group.

BALANCING DEVICE, PARTICULARLY FOR TURBOCOMPRESSORS, AND CORRESPONDING METHOD

A balancing method, particularly for turbocompressors, performed with a balancing device having a base structure which elastically supports a supporting structure having a flange for supporting a receptacle of a rotating element and a rotating element. The balancing device further includes an actuator—adapted to actuate a lever along a substantially radial direction, the lever being adapted to generate a force for fixing the receptacle to the flange. The method includes the following steps: 1. A balancing method , particularly for turbocompressors , performed with a balancing device comprising a base structure which supports elastically a supporting structure which has a flange for supporting a receptacle of a rotating element and a rotating element , said rotating element being movable with a rotary motion about its own rotation axis , and further comprising actuation means adapted to actuate lever means along a substantially radial direction , said lever means being adapted to generate a force for fixing said receptacle to said flange in a direction which is substantially parallel to said rotation axis , the method comprising the steps of:accommodating said receptacle and said rotating element in said supporting structure;translating said lever means with said actuation means which operate along a substantially radial direction;rotating said lever means, by means of the operation of said actuation means, said lever means being adapted to generate a force for fixing said receptacle to said flange in a direction which is substantially parallel to said rotation axis.2. The method according to claim 1 , wherein elastic elements are comprised between said actuation means and said lever means claim 1 , act in a substantially radial direction and are adapted to uncouple mechanically said actuation means from said lever means.3. The method according to claim 2 , wherein in said lever means a power arm to which the force of said actuation means is applied claim 2 , in said ...

Array of age-tailored nutritional formulae with optimum mineral nutrient content

This invention relates to an age tailored nutrition system for infants. In particular, the invention relates to an array of infant formulae for providing an age-tailored nutrition system to an infant, comprising a first infant formula, a second infant formula and an optional third infant formula, wherein (a) said first infant formula being designed to meet the nutritional requirements of an infant from birth to two months, (b) said second infant formula being designed to meet the nutritional requirements of an infant from two months to six months, and (c) said optional third infant formula being designed to meet the nutritional requirements of an infant from six months to twelve months; wherein each of said first, second and third infant formulae comprises suitable amounts of mineral nutrients selected from the group consisting of calcium, iodine, phosphorus, potassium, sodium, copper and zinc, wherein the content of at least one of said mineral nutrients in the second infant formula is lower than in the first infant formula, and the content of said at least one mineral nutrient in the optional third infant formula is lower than in the second infant formula.

Fluid volume determination enhanced by assessment of vehicle operative state

A method of determining a volume of a fluid in a reservoir arranged in a vehicle includes assessing, via a controller, whether a first sensor operatively connected to the reservoir and configured to detect a predetermined level of the fluid in the reservoir has been triggered. The method also includes detecting, via a second sensor, a vehicle operative state indicative of inclination of a free surface of the fluid in the reservoir. The method additionally includes communicating, via the second sensor, the detected vehicle operative state to the electronic controller and determining a degree of inclination of the free surface of the fluid in response to the detected vehicle operative state. Furthermore, the method includes determining, via the controller, the volume of the fluid in the reservoir when the first sensor has been triggered in response to the determined degree of inclination of the free surface of the fluid.

STAPLER FOR MUCOSECTOMY

The head of a stapler for mucosectomy comprises an external goblet-shaped body () wherein an internal goblet-shaped body () is concentrically and slidingly located, at the edge of which a circular blade () is fixed. The internal goblet-shaped body () is provided with a central hole () wherein a rod () is slidingly inserted, at the end () of which an anvil () is fixed. One or more annular grooves (), which are parallel and suitably spaced one from the other, are formed on the lateral surface of the rod () perpendicularly to the axis thereof. Said grooves () are intended to receive a portion of mucosa () which is included in a purse string suture as the mucosa is tied around the rod (). By retracting the rod () in the central hole () of the stem () of the Internal goblet-shaped body (2) the mucosa to be removed is carried into the internal goblet-shaped body (). The anvil () and the circular blade () are moved closer one to the other, by suitable means, in order to cut the tissues when the stapler is in a closed position. 18-. (canceled)9. A method of performing a surgical procedure , comprising:securing a suture to a section of target tissue;securing the suture to a groove of a plurality of longitudinally spaced grooves formed along a rod of an anvil member;drawing the anvil member into a head assembly of a surgical fastener applying apparatus to draw a portion of the section of target tissue into the head assembly; andfiring the surgical fastener applying apparatus to couple a first component of a compression device supported on the anvil member with a second component of the compression device supported on the head assembly about the section of target tissue.10. The method of claim 9 , further comprising inserting the anvil member into an opening in a patient.11. The method of claim 10 , wherein securing the suture to a groove of a plurality of longitudinally spaced grooves includes selecting the groove from the plurality of longitudinally spaced grooves and ...

Gender specific synthetic nutritional compositions and nutritional systems comprising them

Gender specific synthetic nutritional compositions for infants up to 1 month of age contain a caseins content adapted based on that found in human milk produced for an infant of the same gender and age. The compositions can be used in a method of treating, protecting or mitigating sub-optimal growth and development of an infant up to 1 month of age.

Apparatus, System, and Method for Testing Biological Samples

A system for testing biological samples includes a frame having first and second sides and an aperture extending through the frame from the first side to the second side. First and second covers are attached to the first and second sides of the frame to form a well bounded by the frame, the first cover, and the second cover. An electromagnetic imaging device is used to image the biological sample through the first cover. A method is also conceived, wherein a first fluid is supplied to the well, the first fluid including live cells. A biofilm is grown from the live cells. A second fluid is supplied to the well and the biofilm is imaged using the electromagnetic imaging device.

steam reform process to reduce the tar content in syngas streams

PROCESSO DE REFORMA À VAPOR PARA A REDUÇÃO DO TEOR DE ALCATRÃO EM CORRENTES DE GÁS DE SÍNTESE A invenção ora descrita propõe processos de reforma a vapor em duas etapas, sendo a primeira etapa a passagem de uma corrente de gás de síntese, por um primeiro leito catalítico compreendendo um catalisador à base de titanatos de metais alcalinos e/ou de ferro, e uma segunda etapa compreendendo pelo menos um segundo leito catalítico contendo um catalisador metálico em suporte refratário, preferencialmente um catalisador tendo o NiO como fase metálica suportado em hexa-aluminato de bário. STEAM REFORM PROCESS FOR REDUCING THE TAR CONTENT IN SYNTHESIS GAS CHAINS The invention described here proposes steam reform processes in two stages, the first stage being the passage of a stream of synthesis gas through a first bed catalyst comprising a catalyst based on alkali metal and / or iron titanates, and a second step comprising at least a second catalytic bed containing a metal catalyst on refractory support, preferably a catalyst having NiO as the metal phase supported on hexa-aluminate barium.

Odour reduction for agents containing hypochlorite

Antimicrobial compositions for use in products for petroleum extraction, personal care, wound care and other applications

Compositions having antimicrobial activity contain surface functionalized particles comprising an inorganic copper salt which has low water solubility. These types of inorganic salts may also be introduced in porous particles to yield antimicrobial compositions. The compositions may optionally comprise additional antimicrobial agents, salts with high water solubility, organic acids, salts of organic acids and their esters. The compositions may be added to various fluids used in the petroleum extraction industry, or used as coatings on components used in this industry. These antimicrobial materials may be used for reducing both anaerobic and aerobic bacteria and are also useful for reducing corrosion of ferrous components caused by anaerobic bacteria. Although such compositions may be used for any antimicrobial application, and some of the other important uses of these compositions are in wound care, personal care and waste processing.

Liquid extractor assembly from a container

Human anti-cd27 antibodies, methods, and uses

أجسام مضادة آدمية موجهة مناعيا ضد <span dir="LTR">CD27</span> الآدمي يمكن أن تمنع إرتباط <span dir="LTR">CD27</span> مع الليجاند الخاص به <span dir="LTR">CD70</span> ويعادل النشاط البيولوجي لـ <span dir="LTR">CD27</span> بما يتضمن على سبيل المثال وليس الحصر الإشارة بداخل الخلية لـ <span dir="LTR">CD27</span>، تكاثر الخلايا <span dir="LTR">T</span> وتنشيط تكاثر وتمايز الخلايا <span dir="LTR">B</span>، وتكوين الخلايا المكونة لخلايا البلازما وتخفيف استجابات الجسم المضاد، وتنشيط خلايا الأورام عن طريق <span dir="LTR">CD70</span>، وإنتاج مركبات وسيطة قابلة للذوبان من الخلايا <span dir="LTR">T </span> و<span dir="LTR">B</span>. تفيد تلك الأجسام المضادة في تشخيص أو علاج الحالات و الأمراض التي ترتبط بنشاط <span dir="LTR">CD27</span>.

Method and system for management of diabetes with a glucose monitor and infusion pump to provide feedback on bolus dosing

Described and illustrated is a system for management of diabetes that includes an infusion pump, glucose sensor and controller with a method programmed into the controller. The infusion pump is configured to deliver insulin to a subject. The system provides the user with the ability to understand the effects of bolus insulin dosing upon their glucose levels. Specifically, the system provides a message that must include: (a) the trend of the user's glucose; (b) the recommended bolus; and (c) the actual bolus.

Antibodies that bind to lysyl oxidase-like 2 (loxl2) and methods of use therefor.

La presente descripción proporciona agentes de enlace de polipéptidos de lisil oxidasa-tipo 2 (LOXL2), incluyendo por ejemplo, anticuerpos que se enlazan específicamente a un polipéptido LOXL2, y proporciona además composiciones que comprenden los mismos. Los agentes de enlace se pueden usar en diversos métodos de diagnóstico y tratamiento, los cuales se proporcionan también.

Combined day and night solar energy system

A solar heat wave energy system having a solar energy collector that collects energy from the sun to heat a boiler which in turn runs a steam turbine generator for generating electricity during the daytime. The system also has an assembly for generating electricity during the nighttime, which assembly includes a storage structure disposed between the solar collector and the boiler. This storage structure includes a plurality of separate storage stacks, each housed underground and including a plurality of heat conductive pipes interdigitally arranged with a plurality of plates constructed from twice-baked clay and arranged resting on a base formed from a similar clay as the plates. Solar energy is absorbed by the collector and transferred to the storage structure by means of suitable piping for storage in the twice-baked clay plates. When the stored heat is to be later used, as in the nighttime or on overcast days, a switching device uncouples the collector from the storage structure and couples the storage structure to the boiler.

Wet/dry steam condenser

WET/DRY STEAM CONDENSER ABSTRACT A wet/dry steam condenser in accordance with the present invention includes two spaced-apart, vertically aligned groups of heat pipes with each group having the lower, evaporator sections of their respective heat pipes exposed to the interior of an associated, longitudinally extending steam-receiving plenum. The upper, condensing section of each heat pipe is provided with fin structures and can be selectively cooled by a fan-induced air flow and/or deluge water supplied from either a flood water trough and/or a spray-head assembly.

Process and deoxyribonucleic acid for the production of tissue factor protein

FIELD EFFECT TRANSISTORS AND MATERIALS AND METHOD FOR THEIR MANUFACTURE

Virtual core management

A virtual core management system including one or more physical cores and one or more virtual cores. Each virtual core respectively includes a collection of logical states associated with execution of a corresponding program. The virtual core management system further includes one or more interrupt controllers configured to send one or more interrupt signals to interrupt execution of a corresponding program associated with at least one of the one or more virtual cores, and a virtual core management component configured to map the at least one virtual core to one of the one or more physical cores and route the one or more interrupt signals to the corresponding physical core.

Virtual core management

The present disclosure provides methods and systems adapted for use with a processor having one or more physical cores. The methods and systems include a virtual core management component adapted to map one or more virtual cores to at least one of the physical cores to enable execution of one or more programs by the at least one physical core. The one or more virtual cores include one or more logical states associated with the execution of the one or more programs. The methods and systems may include a memory component adapted to store the one or more virtual cores. The virtual core management component may be adapted to transfer the one or more virtual cores from the memory component to the at least one physical core.

Virtual core management

A virtual core management system including one or more physical cores, a virtual core including a collection of logical states associated with the execution of a program, and a virtual core management component configured to map the virtual core to one of the one or more physical cores based upon power management considerations.

Virtual core management

A virtual core management system including a physical core and a first virtual core including a collection of logical states associated with execution of a first program. The first virtual core is mapped to the physical core. The virtual core management system further includes a second virtual core including a collection of logical states associated with execution of a second program, and a virtual core management component configured to unmap the first virtual core from the physical core and map the second virtual core to the physical core in response to the virtual core management component detecting that the physical core is idle.

Virtual core management

A virtual core management system including a first physical core having a first utilization constraint, a second physical core having a second utilization constraint, and a virtual core including a collection of logical states associated with execution of a program. The virtual core management system further includes a utilization indicator configured to measure a utilization of the first physical core with respect to the first utilization constraint and measure a utilization of the second physical core with respect to the second utilization constraint, and a virtual core management component configured to map the virtual core to one of the first physical core and the second physical core based on at least one of the utilization of the first physical core and the utilization of the second physical core.

Virtual core remapping based on temperature

A virtual core management system including a first physical core and a second physical core, and a virtual core including a collection of logical states associated with execution of a program. The virtual core management system further includes a first temperature sensor configured to sense a temperature of the first physical core and a second temperature sensor configured to sense a temperature of the second physical core, and a virtual core management component configured to map the virtual core to one of the first physical core and the second physical core based on at least one of the temperature of the first physical core and the temperature of the second physical core.

Stapler for mucosectomy

The head of a stapler for mucosectomy comprises an external goblet-shaped body (1) wherein an internal goblet-shaped body (2) is concentrically and slidingly located, at the edge of which a circular blade (3) is fixed. The internal goblet-shaped body (2) is provided with a central hole (5) wherein a rod (6) is slidingly inserted, at the end (7) of which an anvil (8; 8') is fixed. One or more annular grooves (11), which are parallel and suitably spaced one from the other, are formed on the lateral surface of the rod (6) perpendicularly to the axis thereof. Said grooves (11) are intended to receive a portion of mucosa (9a) which is included in a purse string suture as the mucosa is tied around the rod (6). By retracting the rod (6) in the central hole (5) of the stem (2a) of the internal goblet-shaped body (2) the mucosa to be removed is carried into the internal goblet-shaped body (2). The anvil (8; 8') and the circular blade (3) are moved closer one to the other, by suitable means, in order to cut the tissues when the stapler is in a closed position.

Three stage medical instrument

A cartridge and an instrument which, together serve to mechanically suture and divide organic tubular structures, such as blood vessels. The cartridge houses a plurality of staples and operates in three stages. After the tubular structure is inserted between the jaws of the cartridge, the cartridge jaws close, a pair of pushers come forward and suture the organic structure in two spaced locations with a pair of surgical staples, and a blade comes forward and divides the tubular structure at a position intermediate the two staples. The staples are indexed and readied for discharge by means of a pair of leaf springs which act between a fixed rail assembly and a movable wrap assembly. The instrument is adapted to coact with the novel cartridge and depends upon the interaction of three springs to bring about the three-stage operation of the cartridge.

Carbon dioxide systems for hydraulic fracturing of hydrocarbon reservoirs

ABSTRACT "Carbon Dioxide Systems for Hydraulic Fracturing of Hydrocarbon Reservoirs" A method of fracturing a subterranean formation with a fracturing fluid comprising as a first phase, from 75% to 99.5% by weight of liquid carbon dioxide and, as a second phase, an organic liquid which is not miscible with liquid CO2 and a selected surfactant. The two-phase mixture or combination is prepared on the surface and injected, with or without added proppant, into the subterranean formation. The fluid demonstrates substantially improved viscosity over other known carbon dioxide-based fracture systems.

Serine threonine kinase receptor

The present invention relates, in general, to a novel serine threonine kinase receptor, ALK-7. In particular, the present invention relates to nucleic acid molecules coding for ALK-7; ALK-7 polypeptides; recombinant nucleic acid molecules; cells containing the recombinant nucleic acid molecules; antibodies having binding affinity specifically to ALK-7; hybridomas containing the antibodies; nucleic acid probes for the detection of ALK-7 nucleic acid; a method of detecting ALK-7 nucleic acid or polypeptide in a sample; and kits containing nucleic acid probes or antibodies. This invention further relates to bioassays using the nucleic acid sequence, receptor protein or antibodies of this invention to diagnose, assess, or prognose a mammal afflicted with neurodegenerative disease. Therapeutic uses for ALK-7 are also provided. This invention also relates to ligands, agonists, and antagonists of the ALK-7 receptor, and diagnostic and therapeutic uses thereof.

GLA monotherapy for use in cancer treatment

The present disclosure relates generally to compositions and methods for treating cancer with a glucopyranosyl lipid A (GLA) in the absence of antigen.

GLA monotherapy for use in cancer treatment

The present disclosure relates generally to compositions and methods for treating cancer with a glucopyranosyl lipid A (GLA) in the absence of antigen.

GLA monotherapy for use in cancer treatment

The present disclosure relates generally to compositions and methods for treating cancer with a glucopyranosyl lipid A (GLA) in the absence of antigen.

GLA monotherapy for use in cancer treatment

The present disclosure relates generally to compositions and methods for treating cancer with a glucopyranosyl lipid A (GLA) in the absence of antigen.

Hybridization and sequencing of nucleic acids

File access system

A system is shown wherein, provided with an appropriate file organization, a data file can be read from a disk master file, given the file name, by performing one seek and one read operation. The system employs hash coding to compress a data file name to a disk file address. The disk file is positioned into fixed length blocks where each hashed file address points to a block, the block being as large as one cylinder or as small as one sector. Each block is organized such that it includes a directory for the files contained in the block and also contains the data files. Each entry in the directory contains the data file name and the address of that data file in the block. The process of locating and reading a data file entails the hash coding of a file name to yield a block address, the moving of the read head to the disk area having the block address and the reading of the directory and the remainder of the block to read out the data file. In the directory reading, the data file names are compared in real time, as they are read from the disk, with the name of the desired data file. When a name match occurs, the address of the data file in the block and the address of the next file address are read and stored. As the disk rotates, the desired data file address just read is constantly compared with the active disk address. When a match occurs, the file has been located and is read out. The reading is terminated at the address of the beginning of the next file. If the file name is not found in the directory of the block indicated by the hash coding of the file''s name, then the file is not present therein.

Method and apparatus for navigation, text input and phone dialing

An apparatus and a method for entering information into an electronic device are provided. The apparatus ( 200 ) includes five text-input buttons ( 102 , etc) that can be activated by pressing or by touching. In one embodiment, the buttons are located on a disk ( 302 ). Text is entered by pressing or touching a single text-input button and then passing a finger or thumb over additional buttons in a prescribed order. The apparatus may be used in conjunction with additional input devices, such as an ‘accept’ or ‘OK’ button. Four navigation buttons ( 104 , etc) are also provided. In one embodiment, these are additional buttons. In a further embodiment, four of the five text-input buttons are selectable as navigation buttons. The selection may be achieved by rotation of the disk ( 302 ) on which the buttons are located. The apparatus may also include a rotatable wheel or roller ( 108 ) to permit scrolling through lists. The apparatus may be used to enter navigation (command), text or number information.

Method and apparatus for navigation, text input and phone dialing

An apparatus and a method for entering information into an electronic device are provided. The apparatus ( 200 ) includes five text-input buttons ( 102 , etc) that can be activated by pressing or by touching. In one embodiment, the buttons are located on a disk ( 302 ). Text is entered by pressing or touching a single text-input button and then passing a finger or thumb over additional buttons in a prescribed order. The apparatus may be used in conjunction with additional input devices, such as an ‘accept’ or ‘OK’ button. Four navigation buttons ( 104 , etc) are also provided. In one embodiment, these are additional buttons. In a further embodiment, four of the five text-input buttons are selectable as navigation buttons. The selection may be achieved by rotation of the disk ( 302 ) on which the buttons are located. The apparatus may also include a rotatable wheel or roller ( 108 ) to permit scrolling through lists. The apparatus may be used to enter navigation (command), text or number information.

Method and apparatus for controlling current in inductive loads such as large diameter coils

A method and apparatus for controlling electric current in loads that are essentially inductive, such that sparking and "ringing" current problems are reduced or eliminated. The circuit apparatus employs a pair of solid state switches (each of which switch may be an array of connected or parallel solid state switching devices such as transistors) and means for controlling those switches such that a power supply supplying two d.c. voltages (e.g. positive 150 volts d.c. and negative 150 volts d.c.) at low resistance may be connected across an essentially inductive load (e.g. a 6 gauge wire loop one hundred meters in diameter) alternatively and such that the first solid state switch is turned off and the second is turned on such that both are not on at the same time but the first turned on and the other on in less time than the inductive time constant (L/R) so that the load is essentially always presented with a low resistance path across its input. In this manner a steady AC current may be delivered to the load at a frequency desired. Shut-off problems are avoided by gradually shortening the period of switching to less than the time constant so that the maximum energy contained in the inductive load is reduced to approximately zero and dissipated in the inherent resistance. The invention circuit may be employed by adjusting the timing of switching to deliver a desired waveform (such as sinusoidal) to the load.

Controller for combustion equipment

(57)【要約】 （修正有） 【課題】 インターレースビデオ信号の帯域幅を維持し ながら、かつプログレッシブビデオ信号の垂直解像度を 保って、 後者の信号から前者の信号に変換する装置、 方法と前者の信号から後者の信号を回復する装置、方法 を提供する。 【解決手段】 プログレッシブ−インタレースビデオコ ンバータ１０は、プログレッシブビデオプレプロセッサ １０５およびコンバータ１１０を含む。後者は、ビデオ フレーム中の１本の走査線を、その前またはその後の走 査線に置き換える。プレプロセッサは、フレーム中の適 切な場所の１本または多数の走査線に所定値を割り当て 得る。各フレームは、少なくとも１本の冗長走査線を有 する。フレーム変更情報は、デジタルビデオストリーム の補助データ部に符号化される。インタレース−プログ レッシブビデオコンバータは、補助データプレプロセッ サと、帰納インタレース−プログレッシブコンバータ と、２つのデジタル標準コンバータとを含む。

Method for making a polyurea-polyurethane composite structure substantially free of volatile organic compounds

A method of making a polyurea—polyurethane composite structure that is substantially free from emission of volatile organic compounds is disclosed. The composite structure produced according to the method of the subject invention has a flexural modulus of at least 200,000 lb/in 2 . The composite structure includes first and second layers. A mold substrate is provided and a first-layer polyisocyanate component and a first-layer resin component are reacted and sprayed onto the mold substrate to form the first-layer. The first-layer polyisocyanate component includes an aliphatic polyisocyanate, and the first-layer resin component includes a polyamine thereby forming a polyurea show surface having a Shore D hardness of at least 65. After application of the first-layer, a second-layer polyisocyanate component and a second-layer resin component are reacted and sprayed behind the first-layer to form the second-layer of the composite structure. The second layer resin component more specifically includes a polyol having a theoretical functionality of at least three. The first and second layers of the composite are substantially free of VOCs.

Compositions and methods for antimicrobial metal nanoparticles

Embodiments of the invention are directed to a composition having antimicrobial activity comprising particles comprising at least one inorganic copper salt; and at least one functionalizing agent in contact with the particles, the functionalizing agent stabilizing the particle in a carrier such that an antimicrobially effective amount of ions are released into the environment of a microbe. The average size of the particles ranges from about 1000 nm to about 4 nm. Preferred copper salts include copper iodide, copper bromide and copper chloride. Preferred functionalizing agents include amino acids, thiols, hydrophilic polymers emulsions of hydrophobic polymers and surfactants.

Antimicrobial compositions comprising surface functionalized particles and uses thereof

Compositions having antimicrobial activity contain surface functionalized particles comprising a copper salt which has low water solubility. The compositions may be added to the articles of manufacture to provide antimicrobial properties. The articles of manufacture include liquid and solid products. These liquids or solids include dispersions, creams, gels, coatings and any thermoplastic or thermosetting, polymer components.

Method and system for recovering and preparing glacial water

Methods and systems for grouping, recovering, and processing ice obtained from an ice source, i.e., a glacier, ice sheet, ice cap, etc., are described herein. In particular, the ice obtained from the ice source is separated and grouped according to common unique properties and processed as a beverage for consumption having the same unique properties. Additionally, methods and systems for producing, trading, transporting, and storing commodities are disclosed. More specifically, methods and systems for producing, trading, transporting, and storing large quantities of water having specific characteristics are provided. Methods for transferring title and trading commodities in the form of water are disclosed.

Method for producing actinium-225

A method for producing Ac-225 is presented, wherein Ac-225 is produced by bombardment of Ra-226 with deuterons accelerated in a cyclotron. The deuterons preferably have an incident energy of between 15 and 22 MeV. The method, which allows production of Ac-225 at high yields and purity levels, is particularly interesting in view of Bi-213 generation.

Method for producing actinium-225

A method for producing Ac-225 is presented, wherein Ac-225 is produced by bombardment of Ra-226 with deuterons accelerated in a cyclotron. The deuterons preferably have an incident energy of between 15 and 22 MeV. The method, which allows production of Ac-225 at high yields and purity levels, is particularly interesting in view of Bi-213 generation.

Method for producing Actinium-225

A method for producing Ac-225 is presented, wherein Ac-225 is produced by bombardment of Ra-226 with deuterons accelerated in a cyclotron. The deuterons preferably have an incident energy of between 15 and 22 MeV. The method, which allows production of Ac-225 at high yields and purity levels, is particularly interesting in view of Bi-213 generation. <IMAGE>

Pendulum pump, in particular to feed oil under pressure to a final device

A pendulum pump to feed oil under pressure to a final device has an outer rotor (11) and an inner rotor (8) which are mounted to rotate around respective rotation axes (10, 12), and a plurality of dragging pendulums (13), which are interposed between the two rotors (8, 11), are rotationally coupled to one of the rotors (8, 11), and are slidingly coupled to respective guide recesses (15) obtained on the other rotor (8, 11); each guide recess (15) having a symmetry plane (P) which is tangent to a circumference (C) which is concentric with respect to the rotation axis (10, 12) of one of the rotors (8, 11).

Machine for manufacturing objects made of plastic material by means of thermoforming

Thermal forming of objects made from plastic material if performed by machine which has first, second and third sectors. The first sector includes structure for unrolling a coil of plastic sheet material. The second sector receives and transports the plastic sheet from the first sector and also heats the plastic sheet as it is moved through the second sector. In the third sector, there is a rotating die which has a plurality of die faces. Each of the die faces is an object form. A first stage of the rotating die receives the heated plastic sheet from the second sector and deforms the heated plastic sheet around the object form to create the object shape. A second stage of the third sector cools the deformed plastic and removes the object from the die faces.

PROCESS FOR THE TOTAL REMOVAL OF ASPARTIC ACID AND GLUTAMIC ACID FROM PROTEIN HYDROLYSATES AND MIXTURES OF AMINO ACIDS WITH THE CONSECUTIVE OBTAINING OF MIXTURES OF AMINO ACIDS OF HIGH NUTRITIONAL VALUE

PROCEDE POUR L'ELIMINATION TOTALE OU PARTIELLE DES ACIDES ASPARTIQUE ET GLUTAMIQUE A PARTIR D'HYDROLYSATS PROTEIQUES OU DE MELANGES D'AMINOACIDES OBTENUS PAR DIVERS TRAITEMENTS, CARACTERISE EN CE QU'IL CONSISTE A FAIRE ADSORBER UNE SOLUTION D'AMINOACIDES SUR UNE RESINE ECHANGEUSE D'IONS DE TYPE ANIONIQUE PUIS A EFFECTUER L'ELUTION. CE PROCEDE PERMET LA PREPARATION DE FORMULATIONS D'AMINOACIDES ADAPTEES A L'UTILISATION EN NUTRITION CLINIQUE.

PROCESS FOR THE TOTAL REMOVAL OF ASPARTIC ACID AND GLUTAMIC ACID FROM PROTEIN HYDROLYSATES AND MIXTURES OF AMINO ACIDS WITH THE CONSECUTIVE OBTAINMENT OF MIXTURES OF HIGH NUTRITION AMINO ACIDS

DEVICE FOR COLLECTING AND SEPARATING PARTICLES AND MICROORGANISMS IN AMBIENT AIR

COUPLING PIECE BETWEEN METAL CABLES WINDOWS AND METAL WIRE ROPE WHEELS

Pièce d'accouplement (1) entre des chemins en métal et des chemins en treillis métallique, comprenant une section (2) à profil en L, ayant une surface horizontale (4) et une surface verticale (5), ladite surface verticale présentant des orifices forés (6). La pièce d'accouplement (1) comprend également une section en porte-à-faux (3) supplémentaire s'étendant depuis la surface verticale (5), ladite section (3) supplémentaire comportant plusieurs fentes (8) découpées sur elle qui forment des pattes (9, 10). Au moins une patte (9) située sur la section en porte-à-faux (3) a une orientation verticale et au moins une des pattes (10) situées sur la section en porte-à-faux (3) a une orientation horizontale. Coupling piece (1) between metal paths and wire mesh paths, comprising an L-section section (2) having a horizontal surface (4) and a vertical surface (5), said vertical surface having drilled orifices (6). The coupling part (1) also comprises an additional cantilever section (3) extending from the vertical surface (5), said additional section (3) having a plurality of slits (8) cut thereon which form legs (9, 10). At least one lug (9) on the cantilever section (3) has a vertical orientation and at least one of the lugs (10) on the cantilever section (3) has a horizontal orientation .

Specific co-aggregation inhibition by arginine

Methods of selectively inhibiting co-aggregation of commensal and pathogenic bacteria in a population of bacteria that comprises commensal and pathogenic bacteria, such as in an individual's oral cavity are disclosed. Methods of reducing biofilm in an individual's oral cavity are disclosed. Methods of inhibiting biofilm formation in a population of bacteria that comprises commensal and pathogenic bacteria are disclosed. Methods of identifying a compound or composition that enhances the selective inhibition of co-aggregation of commensal and pathogenic bacteria by arginine or an arginine oligomer are also disclosed. Methods of identifying a compound or composition that enhances the selective inhibition of biofilm formation of commensal and pathogenic bacteria by arginine or an arginine oligomer are disclosed.

DEVICE FOR THE CONTINUOUS COLLECTION AND COMPACTION OF GARBAGE

Ce dispositif comprend un ensemble transversal de plaques de compactage 1 monté sur un même arbre transversal 2 monté à l'intérieur d'un godet de chargement postérieur 4 muni d'un fond bombé 5, ce godet étant articulé de manière à pouvoir pivoter et étant placé sur des ressorts à boudin 7, le pivotement du godet ayant lieu quand l'excès de détritus compactés empêche la rotation des plaques de compactage 1, le godet étant poussé à son tour et faisant pression sur les ressorts 7, ce qui entraîne le pivotement du godet et libère les détritus obstructifs. Une plaque longitudinale articulée 9 de compactage est fixée dans une glissière horizontale 10, cette plaque articulée étant actionnée par un piston 11 et agissant dans la benne de collecte de résidus, grâce à quoi on obtient une collecte et un compactage continus d'ordures. This device comprises a transverse assembly of compacting plates 1 mounted on the same transverse shaft 2 mounted inside a rear loading bucket 4 provided with a domed bottom 5, this bucket being articulated so as to be able to pivot and being placed on coil springs 7, the pivoting of the bucket taking place when the excess of compacted debris prevents the rotation of the compacting plates 1, the bucket being pushed in turn and putting pressure on the springs 7, which causes the pivoting of the bucket and releases clogging debris. A longitudinal articulated compacting plate 9 is fixed in a horizontal slide 10, this articulated plate being actuated by a piston 11 and acting in the refuse collection bucket, whereby a continuous collection and compaction of refuse is obtained.

Disc for recording sounds

IMPROVED CONNECTION FOR JOINING CHUPS AND / OR CABLES

Raccord amélioré (1) pour la jonction de goulottes et/ou de chemins de câbles, qui comprend une base (3) et plusieurs surfaces latérales (4) ayant des parois verticales qui s'élèvent depuis la base (3), qui délimitent au moins deux ouvertures latérales et qui présentent deux protubérances (5) à l'emplacement desdites ouvertures. Les protubérances (5) comprennent au moins une patte formée sur celles-ci. Improved connector (1) for joining trunking and / or cable trays, which comprises a base (3) and a plurality of side surfaces (4) having vertical walls which rise from the base (3), which delimit at minus two lateral openings and which have two protuberances (5) at the location of said openings. The protuberances (5) comprise at least one tab formed thereon.

Improvements in switches

Gender specific synthetic nutritional compositions and nutritional systems comprising them

PROCESS FOR GLUING ON THE FIRST OF A SEMI-FINISHED SHOE PRODUCT THE SIDES OF THE ASSOCIATED UPPER, AND MACHINE FOR IMPLEMENTING SAME

ELECTROLYTIC INSTALLATION, PARTICULARLY FOR PAINTING A BODY OF A MOTOR VEHICLE BY CATAPHORESIS.

Machine for centrifugal casting of hollow bodies

Thermal regulation device for cooling electrical energy storage devices.

Titre : Dispositif de régulation thermique pour le refroidissement d’organes de stockage d’énergie électrique. L’invention a pour objet principal un dispositif de régulation thermique (4) pour le refroidissement d’organes de stockage d’énergie électrique (2), le dispositif de régulation thermique (4) comportant un tube (6) configuré pour être au contact des organes de stockage d’énergie électrique et comportant au moins un canal de circulation (8) de fluide caloporteur, une boîte de collecte (10) disposée à une extrémité du tube (6) et comportant des chambres de collecte (26) communiquant fluidiquement avec l’au moins un canal de circulation (8) du tube (6), et au moins deux manchons de raccordement (18, 18a, 18b) disposés de part et d’autre de la boîte de collecte (10) et configurés pour communiquer avec la même chambre de collecte (26), les manchons de raccordement (18, 18a, 18b) présentant des formes distinctes l’un par rapport à l’autre. Figure pour l’abrégé : Figure 2 Title: Thermal control device for cooling electrical energy storage devices. The main object of the invention is a thermal regulation device (4) for cooling electrical energy storage devices (2), the thermal regulation device (4) comprising a tube (6) configured to be in contact electrical energy storage devices and comprising at least one coolant fluid circulation channel (8), a collection box (10) arranged at one end of the tube (6) and comprising collection chambers (26) communicating fluidly with the at least one circulation channel (8) of the tube (6), and at least two connection sleeves (18, 18a, 18b) arranged on either side of the collection box (10) and configured to communicate with the same collection chamber (26), the connection sleeves (18, 18a, 18b) having distinct shapes relative to each other. Figure for abstract: Figure 2

Thermal control device for electronic system

La présente invention concerne un dispositif de régulation thermique (1) pour système électronique comprenant un caisson (2) configuré pour accueillir des composants électriques et/ou électroniques (4), ce caisson (2) présentant une paroi de fond (21) et des parois latérales (22) opposées deux à deux définissant un logement interne (3) apte à recevoir les composants électriques et/ou électroniques (4), les faces externes (220) de ces parois latérales (22) étant définies comme celles étant opposées au logement interne (3), ce caisson (2) comportant au moins un élément d’alimentation en fluide de régulation thermique (5) et au moins un élément d’évacuation de fluide de régulation thermique (6). Selon l’invention, cet élément d’alimentation (5) et cet élément d’évacuation (6) sont disposés sur les parois latérales (22) à des distances différentes de la paroi de fond (21). Figure de l’abrégé : Figure 1 The present invention relates to a thermal regulation device (1) for an electronic system comprising a casing (2) configured to accommodate electrical and/or electronic components (4), this casing (2) having a bottom wall (21) and side walls (22) opposite two by two defining an internal housing (3) capable of receiving the electrical and/or electronic components (4), the outer faces (220) of these side walls (22) being defined as those being opposite the internal housing (3), this box (2) comprising at least one thermal regulation fluid supply element (5) and at least one thermal regulation fluid discharge element (6). According to the invention, this supply element (5) and this evacuation element (6) are arranged on the side walls (22) at different distances from the bottom wall (21). Abstract Figure: Figure 1

High-temperature reactor associated with a plasma generation zone, in particular a mixed electricity-fuel burner

In a reactor such as that of the main patent, the plasma is generated in a reducing medium in order to minimise the formation of nitrogen oxides and the erosion of the electrodes 25, which receive an additional protection against oxidation by injection of a part of the fuel as plasma-generating gas G in their neighbourhood. The configuration of the chamber 20 is such that an acceleration of the fuel is performed by a converging cone 21a and then a stabilisation of the flame by a diverging cone 21b into which air is injected. Application as electrical burner.

Thermal regulation device for cooling electrical energy storage devices.

Titre : Dispositif de régulation thermique pour le refroidissement d’organes de stockage d’énergie électrique. L’invention a pour objet principal un dispositif de régulation thermique (4) pour le refroidissement d’organes de stockage d’énergie électrique (2), le dispositif de régulation thermique (4) comportant un tube (6) configuré pour être au contact des organes de stockage d’énergie électrique et comportant au moins un canal de circulation (8) de fluide caloporteur, une boîte de collecte (10) disposée à une extrémité du tube (6) et comportant des chambres de collecte (26) communiquant fluidiquement avec l’au moins un canal de circulation (8) du tube (6), et au moins deux manchons de raccordement (18, 18a, 18b) disposés de part et d’autre de la boîte de collecte (10) et configurés pour communiquer avec la même chambre de collecte (26), les manchons de raccordement (18, 18a, 18b) présentant des formes distinctes l’un par rapport à l’autre. Figure pour l’abrégé : Figure 2 Title: Thermal control device for cooling electrical energy storage devices. The main object of the invention is a thermal regulation device (4) for cooling electrical energy storage devices (2), the thermal regulation device (4) comprising a tube (6) configured to be in contact electrical energy storage devices and comprising at least one coolant fluid circulation channel (8), a collection box (10) arranged at one end of the tube (6) and comprising collection chambers (26) communicating fluidly with the at least one circulation channel (8) of the tube (6), and at least two connection sleeves (18, 18a, 18b) arranged on either side of the collection box (10) and configured to communicate with the same collection chamber (26), the connection sleeves (18, 18a, 18b) having distinct shapes relative to each other. Figure for abstract: Figure 2

Plastics exterior handle for motor vehicle door - has direct handle to door steel fixing eliminating rubber joint and retained by screws

The handle has a central grip (10) and two end bases (22,23), fixed direct to the car by screws (13,14). The bases have lipped profiles to give a better fixing to the door and greater stability to the handle. The handle also has a plastics push button (11) to operate the door lock, with a key barrel incorporated in the push button. The push button slides in the housing (24) in the base (23), pushes against a return spring (15), and works a rod (14) which, in turn, operates the door lock.

Improvements to suitcases or other baggage to facilitate transport

CABLES IN WIRE THREAD OF COUPLEABLE YARNS AND METHOD FOR JOINING SECTIONS OF SAID PLATE

Un plateau de câbles en treillis de fils pouvant être accouplé (1) est constitué de plusieurs fils métalliques longitudinaux (2, 2') et transversaux (3, 3', 3") réunis, les fils transversaux (3, 3', 3") ayant une forme de U, de manière à former une surface de base et deux surfaces latérales. L'une des extrémités longitudinales (A) comprend au moins deux fils transversaux (3 en U, des extrémités d'au moins deux fils latéraux longitudinaux (2') et des extrémités de fils longitudinaux (2) de la base. L'extrémité longitudinalement opposée (B) comprend au moins deux fils transversaux (3') en U, des extrémités d'au moins deux fils latéraux longitudinaux (2 et des extrémités de fils longitudinaux (2) de la base. Les deux derniers fils transversaux (3') d'une extrémité (A) sont mutuellement séparés de la même distance que celle entre les deux derniers fils transversaux (3") de l'extrémité opposée (B). A mating wire mesh tray (1) consists of a plurality of longitudinal (2, 2 ') and cross (3, 3', 3 ") metal wires joined together, the transverse wires (3, 3 ', 3 ") having a U shape, so as to form a base surface and two side surfaces. One of the longitudinal ends (A) comprises at least two transverse wires (3 in U, ends of at least two longitudinal lateral wires (2 ') and ends of longitudinal wires (2) of the base. longitudinally opposite (B) comprises at least two U-shaped transverse wires (3 '), ends of at least two longitudinal lateral wires (2) and longitudinal wire ends (2) of the base, and the last two transverse wires (3). ') at one end (A) are mutually separated by the same distance as between the last two transverse wires (3 ") of the opposite end (B).

Clutch mechanism, in particular for a motor vehicle.

A clutch mechanism comprising a cover (11), a pressure plate (13) and two diaphragms (14A, 14B) therebetween each having a peripheral portion (15A, 15B) forming a Belleville washer engaging the cover (11) and bearing on the pressure plate (13), as well as a central portion (17A, 17B) divided into radial projections (18A, 18B) by slots. Said peripheral portions (15A, 15B) of the two diaphragms (14A, 14B) are substantially axially spaced apart and have, in absolute values, different geometrical characteristics such that the characteristic curve of the assembly preferably does not dip. Said mechanism is particularly useful as a clutch mechanism for motor vehicles.

HIGH TEMPERATURE REACTOR ASSOCIATED WITH A PLASMAGENESIS AREA, IN PARTICULAR A MIXED ELECTRICITY-FUEL BURNER

Compositions and methods for antimicrobial metal nanoparticles

Embodiments of the invention are directed to a composition having antimicrobial activity comprising particles comprising at least one inorganic copper salt; and at least one functionalizing agent in contact with the particles, the functionalizing agent stabilizing the particle in a carrier such that an antimicrobially effective amount of ions are released into the environment of a microbe. The average size of the particles ranges from about 1000 nm to about 4 nm. Preferred copper salts include copper iodide, copper bromide and copper chloride. Preferred functionalizing agents include amino acids, thiols, hydrophilic polymers, emulsions of hydrophobic polymers and surfactants.

Gender specific synthetic nutritional compositions and nutritional systems comprising them

Gender specific synthetic nutritional compositions for infants 4 to 8 months of age, 1 to 2 months of age, or up to 1 month of age wherein, the concentration of methionine is adapted based on that found in HM produced for an infant of the same gender and age, and nutritional systems comprising them.

Compression device for anastomosis of hollow organs

SUPPORT FOR PORTABLE TRAYS

A plastic bottle for hot filling

A plastic bottle for hot filling, of the type including a circumferential lateral wall (10), which is incorporated at its lower part to a bottom portion (F) and at its upper part to a neck portion (G) of said bottle, and comprising a plurality of grooves (20), incorporated along the lateral wall (10) and disposed slightly inclined in relation to the longitudinal axis of the bottle and spacedl y in relation to said bottom portion (F) and neck portion (G). said grooves (20) being substantially parallel and spaced from each other by panels (11) of said lateral wall (10), said grooves (20) having a wall thickness, which is symmetrical in relation to the respective longitudinal planes of symmetry and which is dimensioned so that said grooves provide a vertical reinforcement, absorb homogeneously and make imperceptible the circumferential thermal and mechanical contractions of the bottle after cooling.

Ultrasonic system and method for detecting a biofilm on a tooth

An ultrasonic system may include: an oral care device including: a head; a plurality of teeth cleaning elements extending from a first side of the head; and an ultrasound module including an ultrasound transceiver positioned in the head, the ultrasound transceiver configured to produce an ultrasound signal on the first side of the head and to generate a detection signal from a reflected ultrasound signal; and a processing module operably coupled to the ultrasound module to receive the detection signal; wherein the processing module includes a programmable processor configured to process the detection signal non-linearly with respect to time by first identifying a first reflection representing a surface of a tooth and then determining whether a second reflection peak is present in the detection signal at a time prior to the first reflection peak, the second reflection peak representing a biofilm on the surface of the tooth.

Device for applying liquid adhesive to a surface, particularly in the footwear manufacture

E' descritto un dispositivo comprendente almeno un ugello (20) dispensatore d'adesivo liquido, mezzi di supporto e d'azionamento (22-27) atti a spostare l'ugello (20) lungo un percorso prefissato (30s, 30d) e mezzi (36) d'adduzione d'adesivo liquido all'ugello. Per applicare l'adesivo in diverse direzioni senza ricorrere ad organi per la rotazione dell'ugello, l'ugello (20) presenta almeno due fori (33, 34) d'efflusso dell'adesivo diversamente orientati e mezzi (32, 37, 41) per attivare o disattivare selettivamente l'efflusso stesso attraverso i fori. Nella forma d'esecuzione descritta tali mezzi comprendono un organo di distribuzione (32) scorrevole all'interno dell'ugello (20) per mettere in comunicazione selettivamente i mezzi (36) d'adduzione dell'adesivo con l'uno o con l'altro dei fori (33, 34) d'efflusso dell'ugello (20).