AERODYNAMIC DEVICE FOR MOTOR VEHICLE

PHARMACEUTICAL COMPOSITION ANTITHROMBOTIQUE

LIMP OF ARRANGEMENT TO MIX TO SPARE OF PLUNGING TYPE.

THERAPEUTIC USE OF IMIDAZOPYRIDINE DERIVATIVES

CELLULOSE BEADS EXFOLIATING AND COSMETIC USES THEREOF

La présente invention concerne des particules de cellulose ayant des propriétés d'exfoliation mesurables, leur utilisation dans le domaine cosmétique.

ELEMENT OF FILTRATION FOR WATER CARAFE

USE OF COMPOSE REDUCING the APOPTOSE

WATERPROOFING SYSTEM AND OF RETRACTABLE PROTECTION SPLIT Cold

USE OF A PYRAZOLE DERIVATIVE FOR THE PREPARATION OF MEDICAMENTS USEFUL IN THE PREVENTION OR TREATMENT OF RENAL DISEASES

TOGETHER Of ARTICULATION AND TOGETHER ARM HAS ARTICULATE COMPRISING AT LEAST SUCH a SET Of ARTICULATION

Cet ensemble d'articulation (1) d'au moins un bras mobile autour d'un bras fixe comporte : un corps d'articulation (2) comportant au moins une partie délimitée par une paroi externe semi-cylindrique (6a ; 6b), un perçage (11A ; 11B) pour la réception d'un axe de pivotement (12A ; 12B) et des zones en creux (8A ; 8B-9B) formées radialement sur ladite paroi semi-cylindrique ; et un embout (4A ; 4B) comportant des pattes (24a-24b ; 24'a-24'b ) comportant chacune un orifice (25a-25b ; 25'a-25'b) en regard dudit perçage (11A ; 11B) pour le passage dudit axe de pivotement (12A ; 12B), ledit embout (4A ; 4B) comportant également au moins un logement (27a ; 27b) recevant un élément de type ressort (29a-29b ; 29'a-29'b) monté pour repousser un organe de blocage dans une zone en creux (8A ; 8B-9B) correspondant à une position angulaire du bras mobile.

JOINT ASSEMBLY AND ARTICULATED ARM ASSEMBLY COMPRISING AT LEAST ONE SUCH JOINT ASSEMBLY

NEW DERIVATIVES Of INDOLOZINE-1,2,3 SUBSTITUEE, SELECTIVE INHIBITORS OF the B-FGF

AERODYNAMIC DEVICE FOR A MOTOR VEHICLE

USE INTO THERAPEUTIC OF DERIVED From IMIDAZOPYRIDINE

L'invention concerne l'utilisation de composés répondant à la formule (I) : dans laquelle - R2 et R3 forment ensemble, avec les atomes de carbone du noyau phényle auquel ils sont rattachés, un hétérocycle azoté à 6 chaînons répondant à l'une des formules (A), (B) ou (C) ci-dessous : dans lesquelles les traits ondulés représentent le noyau phényle auquel R2 et R3 sont rattachés, ou d'un de ses sels pharmaceutiquement acceptables pour la préparation d'un médicament pour le traitement du cancer de la vessie.

AUTONOMOUS LIGHTING SYSTEM FOR BICYCLE APPLYING A BRAKE DYNAMO

DERIVED From IMIDAZOPYRIDINE, THEIR METHOD OF PREPARATION AND THEIR APPLICATION INTO THERAPEUTIC

L'invention concerne des composés répondant à la formule (I) : dans laquelle - R2 et R3 forment ensemble, avec les atomes de carbone du noyau phényle auquel ils sont rattachés, un hétérocycle azoté à 6 chaînons répondant à l'une des formules (A), (B) ou (C) ci-dessous : dans lesquelles les traits ondulés représentent le noyau phényle auquel R2 et R3 sont rattachés.

DERIVED From INDOLIZINES, METHODS OF PREPARATION AND APPLICATION INTO THERAPEUTIC

L'invention concerne des composés répondant à la formule (I) : dans laquelle : - R3 et R4 forment ensemble, avec les atomes de carbone du noyau phényle auquel ils sont rattachés, un hétérocycle azoté à 6 chaînons répondant à l'une des formules (A), (B) ou (C) ci-dessous : dans lesquelles les traits ondulés représentent le noyau phényle auquel R3 et R4 sont rattachés.

USE Of AGONISTES OF RECEIVERS OPIOIDES DELTA IN the FIELD OF the COSMETIC AND the DERMOCOSMETIQUE

La présente invention concerne l'utilisation d'un ligand des ROD pour la stimulation de la pigmentation dans une composition cosmétique et l'utilisation de rubiscoline 6 ou de ses dérivés dans une composition cosmétique. The present invention relates to the use of an ROD ligand for the stimulation of pigmentation in a cosmetic composition and the use of rubiscoline 6 or its derivatives in a cosmetic composition.

FILTER FOR the PRODUCTION OF ICE CONCASSEE BY MEANS OF a MIXEUR PLUNGING AND DEVICE FOR the PRODCUTION OF ICE CONCASSEE PROVIDED With SUCH a FILTER

MOTOR VEHICLE EQUIPS With a HOOD OPTIMIZES

USE Of a DRIFT OF the PYRAZOLE, FOR the PREPARATION OF USEFUL DRUGS IN the PREVENTION AND the TREATMENT OF the METABOLIC SYNDROME

ABSORBER PLATE FOR AIR CONDITIONER

THE USE OF DELTA OPIOID RECEPTOR AGONISTS IN THE FIELD OF COSMETICS AND DERMOCOSMETIC

NEW DERIVATIVES Of INDOLIZINE 1,2,3,6,7,8 SUBSTITUEE, INHIBITORS OF the FGFS, LEURPROCEDE OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS the CONTAINER.

HEXADECASACCHARIDES BIOTINYLES, THEIR PREPARATION AND THEIR THERAPEUTIC USE

N- [...][...][...] DES CYLINDERS DES FGFs, THEIR PREPARATION AND THEIR APPLICATION EN [...]

Octasaccharides N-acyles activateurs des récepteurs des FGFs, répondant à la formule (I) : dans laquelle : - R1 représente un groupe O-alkyle éventuellement substitué par un ou plusieurs groupes aryles ou cycloalkyles, - R2 représente un groupe OSO3- ou hydroxyle, - R3 représente un groupe alkyle, cycloalkyle ou alkyl-cycloalkyle, et - R4 représente un disaccharide de formule (II), R6 représente un disaccharide de formule (III) et R8 représente un disaccharide de formule (IV), où R5, R7 et R9 représentent des groupes OSO3- ou hydroxyles : Leur préparation et leur application en thérapeutique.

VESSEL HAVING INSULATING BLOCKS CORNER EQUIPPED WITH SLOTS RELAXATION

L'invention concerne une cuve étanche et thermiquement isolante de stockage d'un fluide comprenant un arrangement d'angle (12) disposé à l'intersection entre le première et la deuxième parois (1, 2) et comportant : - un premier et un second blocs isolants (30, 31) respectivement retenus à la première et à la seconde parois (1, 2) de la structure porteuse et formant un coin de la barrière thermiquement isolante (5) ; et - une structure d'angle métallique (49, 50, 51) formant un coin de la membrane d'étanchéité (6) qui est soudée sur la pluralité des platines métalliques (38) du premier et du second blocs isolants (30, 31) ; chacun des premier et second blocs isolants (30, 31) étant associé à un panneau isolant (9) adjacent par l'intermédiaire d'un élément de pontage (44) ; chacun des premier et second blocs isolants (30, 31) présentant au moins une première et une deuxième fentes de relaxation (45, 48) s'étendant respectivement parallèlement et perpendiculairement à l'intersection entre ...

SYSTEM OF PROSTHESIS OF HIP

VESSEL HAVING INSULATING BLOCKS CORNER EQUIPPED WITH SLOTS RELAXATION

ANTI-CANCER DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION INTO THERAPEUTIC

BIFACIAL WHEEL, COMPRESSOR, A TURBINE, TURBOCHARGER AND ASSOCIATED PUMP

L'invention concerne une roue (1) de machine tournante pour un fluide, comportant un axe de roue (A), des pales (124) et un flasque (12) raccordé aux faces intrados (1241) des pales (124) par des congés intrados (1251), caractérisée en ce que le flasque (12) est évidé au niveau d'une portion périphérique d'une face intrados (1251) de sorte qu'un congé intrados (1251) est compris dans un cylindre caractéristique (B) d'axe de révolution l'axe de roue (A) et de diamètre égal aux deux tiers du diamètre d'un cylindre périphérique (C). La roue (1) comporte également des nervures (121) de renfort raccordées aux faces extrados (1242).

PROCESS AND Control system Of a HEAT PUMP REVERSIBLE HAS THERMOELECTRIC MODULES

L'invention concerne le contrôle d'une pompe à chaleur thermoélectrique réversible qui comprend des unités thermoélectriques (41, 42, 43, 44) avec plusieurs modules thermoélectriques (3) permettant de transférer de la chaleur entre deux circuits de la pompe. Il est prévu en particulier de : - fournir une pluralité de connexions de sortie (S1, S2, S3, S4) de l'alimentation électrique (10) des unités thermoélectriques ; - programmer au moins une consigne de température ; - délivrer, par des capteurs de température (31), des signaux représentatifs de températures caractéristiques des deux circuits ; - régler la tension délivrée au niveau de chacune des connexions de sortie, en commandant ladite alimentation électrique, un dispositif de commutation (20) étant configuré en fonction de la consigne de température et desdits signaux, la configuration du dispositif de commutation étant sélectionnée parmi une pluralité de configurations avec jusqu'à deux niveaux au moins de tension d'alimentation ...

DERIVED From IMIDAZOPYRIDINE, THEIR METHOD OF PREPARATION AND THEIR APPLICATION INTO THERAPEUTIC

USE OF DELTA OPIOID RECEPTOR AGONISTS IN COSMETICS AND DERMOCOSMETIC

La présente invention concerne l'utilisation d'un ligand des ROD pour la stimulation de la pigmentation dans une composition cosmétique et l'utilisation de rubiscoline 6 ou de ses dérivés dans une composition cosmétique.

BLEACH HYDROLYSIS OF CELLULOSE WITH SUBSTANTIALLY REDUCED USE OF CHLORINE

The present invention provides in a multistage process for fully bleaching a pulp, the improvement in which in the first stage of said bleaching process, the pulp is hydrolyzed with a strongly alkaline aqueous peroxide solution whereby a minimum of chlorine may be used in said process.

N- [...][...][...] DES CYLINDERS DES FGFs, THEIR PREPARATION AND THEIR APPLICATION EN [...]

DERIVED From INDOLIZINES, METHODS OF PREPARATION AND APPLICATION INTO THERAPEUTIC

[...]-STABILISED KNEE PROSTHESIS.

THE USE OF DELTA OPIOID RECEPTOR AGONISTS IN THE FIELD OF COSMETICS AND DERMOCOSMETIC

Absorption plate for air-conditioner of car, has temperature-homogenizing unit arranged along exchange grids for absorbing fluid flow, where plate is traversed by absorbing fluid flow flowing out along grids

Plaque d'absorption de climatiseur pour véhicule, traversée par un flux de fluide absorbant (10) s'écoulant le long d'au moins une surface d'échange (30), l'absorption exothermique d'un fluide réfrigérant se faisant au travers de ladite au moins une surface d'échange (30) par augmentation d'une concentration du fluide réfrigérant dans le fluide absorbant (10), caractérisée en ce que la plaque comporte le long de ladite au moins une surface d'échange (30) des moyens d'homogénéisation de la température du flux de fluide absorbant (10) ...

NEW DERIVATIVES OF BENZENE, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL LESCOMPOSITIONS THE CONTAINER

NEW POLYSACCHARIDES HAS ACTIVITY ANTITHROMBOTIQUE INCLUDING/UNDERSTANDING AT LEAST COVALENT UNELIAISON WITH THE BIOTINE OR A DRIFT OF THE BIOTINE

MAGNETIC IMMUNODIAGNOSTIC METHOD FOR THE DEMONSTRATION OF ANTIGEN/ANTIBODY COMPLEX, IN PARTICULAR BLOOD GROUP

INSULATING MATERIALS USED AS INSULATING OR SEALING LAYERS FOR ROOFS

Filling device for bottles

HERSTELLUNG BIOLOGISCH ABBAUBARER, EINEN BIOLOGISCH AKTIVEN STOFF ENTHALTENDER, MIKROPARTIKEL

Bildverwendungssoftware die eine Liste von durch den Benutzer auswählbaren Aufgaben bereitstellt

Machine for inserting geo-plastic beneath track

NIGELLA EXTRACTS FOR THE TREATMENT OF SYMPTOMS CONNECTED TO IMPAIRED OR IMBALANCED NEUROTRANSMISSION

The present invention relates to the use of sp. extracts and their volatile components for the treatment of symptoms connected to impaired neurotransmission in animals including humans as well as to dietary supplements, food and feed or nutraceutical compositions containing such extracts or their volatile components. 1Nigella. An oral dietary or nutraceutical composition comprising a lipophilic sp. seed extract in a effective amount for the treatment of symptoms connected to impaired or reduced neurotransmission in an animal.2Nigella. The composition of wherein the sp. seed extract is obtained by an extraction method selected from the group consisting of: liquid carbon dioxide under supercritical conditions claim 1 , steam distillation/hydrodistillation yielding essential oils claim 1 , ethanol extraction claim 1 , ethyl acetate extraction claim 1 , methyl-tert.-butylether claim 1 , methanol claim 1 , propane claim 1 , butane claim 1 , acetone and nitro oxide.3. A dietary composition comprising a composition according to claim 1 , selected from the group consisting of: fortified food claim 1 , spicy cereal bars claim 1 , bakery items claim 1 , cookies claim 1 , dietary supplements claim 1 , non-alcoholic drinks claim 1 , soft drinks claim 1 , sport drinks claim 1 , vegetable juices claim 1 , teas claim 1 , liquid food claim 1 , and soups.4Nigella sativa.. A composition according to which is from5Nigella. Use of a lipophilic sp. seed extract according to for the manufacture of a composition for the treatment of a disorder connected to impaired neurotransmission in healthy people or animals.6. Use according to claim 5 , wherein the composition is a mood/vitality improver claim 5 , a stress reliever claim 5 , a condition improver claim 5 , a reducer of anxiety claim 5 , a reducer of tension claim 5 , a reducer of unhappiness/discontentedness claim 5 , a reducer of irritability claim 5 , a reducer of dysphoria claim 5 , a reducer of obsessive-compulsive behaviour claim ...

SCIENCE, TECHNOLOGY, ENGINEERING AND MATHEMATICS BASED CYBER SECURITY EDUCATION SYSTEM

According to one aspect, a science, technology, engineering and mathematics (STEM) based cyber security education system is provided. A training component, a knowledge component, and a collaborative component are interfaced to a distance learning component to form a STEM-based cyber security education system interface on an educational content server. The educational content server is coupled to a content database configured to access STEM-based cyber security educational content associated with one or more of: the training component, the knowledge component, and the collaborative component. Asynchronous delivery of the STEM-based cyber security educational content is provided to an end user computer in response to a user request. An interactive session is established between one or more experts and the end user computer to provide synchronous delivery of STEM-based cyber security materials. 1. A method for providing a science , technology , engineering and mathematics (STEM) based cyber security education system , the method comprising:interfacing a training component, a knowledge component, and a collaborative component to a distance learning component to form a STEM-based cyber security education system interface on an educational content server;coupling the educational content server to a content database configured to access STEM-based cyber security educational content associated with one or more of: the training component, the knowledge component, and the collaborative component;providing asynchronous delivery of the STEM-based cyber security educational content to an end user computer in response to a user request; andestablishing an interactive session between one or more experts and the end user computer to provide synchronous delivery of STEM-based cyber security materials.2. The method of claim 1 , wherein the training component comprises one or more of: on-line simulations claim 1 , self-study web based training modules claim 1 , audio/video conference ...

PHYTASE IN READY-TO-DRINK SOFT DRINKS

The present invention relates to an acidic ready to drink beverage having a water activity greater than 0.95, a pH value lower than 6, and enriched with an active phytase enzyme. 1. Ready to drink phytate free and alcohol free soft drink having a water activity greater than 0.95 , a pH value lower than 6 , a protein content below 3 wt.-% , and enriched with 10 to 50000 FTU/litre phytase enzyme.2. A ready to drink phytate free and alcohol free soft drink according to claim 1 , characterized in that the pH is comprised between 2.5 and 5.5.3. A ready to drink phytate free and alcohol free soft drink according to any of the or claim 1 , characterized in that the pH is comprised between 3 and 5.5.43. A ready to drink phytate free and alcohol free soft drink according to any of the to claims 1 , characterized in that it contains 0.5 to 4 g/l citric acid.54. A ready to drink phytate free and alcohol free soft drink according to any of the to claims 1 , characterized in that it is enriched with 50 to 20000 FTU per litre.65. A ready to drink phytate free and alcohol free soft drink according to any of the to claims 1 , characterized in that the fat content is lower than 1 wt.-%.76Aspergillus.. A ready to drink phytate free and alcohol free soft drink according to any of the to claims 1 , characterized in that the phytase is of microbial origin and is preferably from the fungus87. A ready to drink phytate free and alcohol free soft drink according to any of the to claims 1 , characterized in that it is aseptically filled claims 1 , pasteurized or carbonated.98. A ready to drink phytate free and alcohol free soft drink according to any of the to claims 1 , characterized in that it is further enriched with nutrients claims 1 , further enzymes claims 1 , flavoring agents claims 1 , or mixtures thereof.109. A ready to drink phytate free and alcohol free soft drink according to any of the to claims 1 , characterized in that the phytase activity is at least 50% of the initial ...

USES OF AGONISTS OF DELTA OPIOID RECEPTOR IN COSMETIC AND DERMOCOSMETIC FIELD

The present invention relates to the use of a DOR ligand for stimulating pigmentation in a cosmetic composition and to the use of rubiscolin-6 or its derivatives in a cosmetic composition. 1. A cosmetic method for stimulating pigmentation of skin or hair , comprising applying to human skin and/or hair a composition comprising an agonist of δ opioid receptor.2. The method of claim 1 , wherein the agonist of δ opioid receptor is selective for delta opioid receptor claim 1 , and preferably selected from the group consisting of BU-48 claim 1 , SNC-80 claim 1 , C-8813 claim 1 , DPI-287 claim 1 , DPI-221 claim 1 , TAN-67 claim 1 , BW373U86 claim 1 , SIOM claim 1 , RWJ-394 claim 1 ,674 claim 1 , rubiscolin-6 and its derivatives having an activity of agonist of δ opioid receptor claim 1 , deltorphin and its derivatives having an activity of agonist of δ opioid receptor claim 1 , DPDPE claim 1 , DSLET claim 1 , JOM-13 claim 1 , DSTBULET claim 1 , BUBU claim 1 , and BUBUC.3. The method of claim 2 , wherein the agonist of δ opioid receptor is a peptide selected from rubiscolin-6 and its derivatives having an activity of agonist of δ opioid receptor.5. The method of claim 4 , wherein the agonist of δ opioid receptor is a peptide selected from the group consisting of or a peptide having an activity of agonist of δ opioid receptor and comprising a sequence selected in the group consisting of YPLDLF (SEQ ID No 1) claim 4 , YPIDLF (SEQ ID No 7) claim 4 , YPMDLF (SEQ ID No 8) claim 4 , YPLDIF (SEQ ID No 9) claim 4 , YPLDLL (SEQ ID No 10) claim 4 , YPLDLI (SEQ ID No 11) claim 4 , YPLDLM (SEQ ID No 12) claim 4 , YPLDLV (SEQ ID No 13) claim 4 , YPLDLA (SEQ ID No 14) claim 4 , YPIDLV (SEQ ID No 15) claim 4 , YPMDLV (SEQ ID No 16) claim 4 , YPLDIV (SEQ ID No 17) claim 4 , YPIDIV (SEQ ID No 18) claim 4 , YPMDIV (SEQ ID No 19) claim 4 , YPIDLV (SEQ ID No 20) claim 4 , YPIDMV (SEQ ID No 21) claim 4 , YPIDII (SEQ ID No 22) claim 4 , YPMDII (SEQ ID No 23) claim 4 , YPMDL (SEQ ID No 24) claim ...

SURFCRAFT FIN ASSEMBLY

A surfcraft fin assembly includes a generally rectangular open mounting box recessed into the underside of surfcraft and having lugs projecting internally at the front and rear of its open edge to retain a notch in the leading edge of the base of the fin and a flexible hook in the rear edge of the base of the fin which flexes allowing insertion into and removal from the mounting box. 1. A surfcraft fin assembly comprising a generally rectangular open mounting box anda fin with a base;the base having a notch in one end and a flexible portion at the other end,the mounting box being adapted to be recessed into the underside of a surfcraft and having two long side edges and short front and rear edges, said front and rear edge having lugs projecting internally to retain the fin in the box by engaging the notch in the base and the flexible portion of the base which flexes to allow insertion into and removal from the mounting box.2. The surfcraft fin assembly of wherein the flexible portion is biased away from the fin such that during insertion it flexes towards the fin to allow insertion and once pressed past the lug springs away from the fin and under the lug to retain the fin in the mounting box.3. The surfcraft fin assembly of further comprising a lever which can be used to prise the flexible portion of the fin base away from the lug to remove the fin from the mounting box.4. The surfcraft fin assembly of wherein the fin base has a leading edge with a notch and a rear edge with a flexible portion.5. The surfcraft fin assembly of wherein the fin base has a leading edge with a flexible portion and a rear edge with a notch.6. The surfcraft fin assembly of wherein the flexible portion is a flexible hook.7. The surfcraft fin assembly of wherein the lugs are integrally formed with the box.8. The surfcraft fin assembly of in which the lugs are removably fastened to the box and are designed to snap off when the fin encounters an obstacle thus releasing the fin.9. The surfcraft ...

METHOD OF MARKETING OREGANO CAPSULES CONTAINING THYMOQUINONE

This invention relates to a method of marketing capsule formulations for pharmaceutical, nutraceuticals or food supplements which contain oregano oil containing thymoquinone (THQ) as an active ingredient at a concentration of least 2 weight % and which can be stored at room temperature. The capsules have a hydroxypropylmethylcellulose (HPMC) shell and may contain carvacrol (CRV) as an additional active ingredient, either in synthetic form, or as part of a plant extract. Optionally, the capsules may contain a viscosity agent. The method includes the steps of advising a potential consumer of the benefits of THQ, and optionally CRV and providing a kit containing these capsules. 1. A method of marketing a capsule comprising: a) shell selected from the group consisting of: hydroxypropylmethylcellulose (HPMC), pullulan, and gelatin;', 'b) a fill composition comprising an oregano extract comprising at least 2 weight % thymoquinone (THQ),', 'c) a diluent selected from the group consisting of: middle chain triglycerides, glycerol, edible vegetable waxes; plant oils, and mixtures thereof; and', 'd) a viscosity increasing agent, with the proviso that the viscosity increasing agent is not phosphaditylcholine, and with the further proviso that when the shell is pullulan or gelatin, then the viscosity increasing agent comprises neither phosphatidylcholine nor lecithin; and, 'providing a kit, wherein the kit comprises a plurality of capsules in a capsule container, wherein each capsule comprisesproviding informational material which comprises informs a potential consumer about the benefits of a capsule containing oregano extract comprising thymoquinone.2. A method according to wherein the capsules contain from 2-8 weight % thymoquinone.3. A method according to wherein the plaint oil diluent is selected from the group consisting of olive oil claim 1 , palm oils claim 1 , sunflower oils claim 1 , maize/corn oil claim 1 , soybean oil claim 1 , sesame oil claim 1 , and rice bran oil.4 ...

Protective Covers for Sports Equipment Handles

This present invention relates to a protective cover for use with a handle on a piece of sports equipment, such as a baseball bat, to protect the handle from the elements (e.g., rain, sleet, snow) and/or physical damage. The protective cover preferably includes a contoured interior with an integrated memory foam that provides a convenient location to place a pair of cleats or other accessory, a hook and loop fastener positioned on the exterior surface to attach additional accessories, and a patch or other surface upon which useful information may be recorded and displayed.

Novel coating system (ii)

The present patent application relates to a novel coating system for coating solid particles, which comprise PUFAs (and/or salts thereof), wherein the coating comprises at least one protein hydrolysate. Furthermore it relates to compositions coated with such a coating system and the use of such compositions in the production of food, feed, dietary supplements and/or pharmaceutical products.

NOVEL COATING SYSTEM (I)

The present patent application relates to a novel coating system for coating solid particles, which comprise PUFAs (and/or salts thereof), wherein the coating comprises at least one cyclodextrin. Furthermore it relates to compositions coated with such a coating system and the use of such compositions in the production of food, feed, dietary supplements and/or pharmaceutical products. 1. A coating system comprisingat least 10 wt-%, based on the total weight of the coating system, of cyclodextrin.2. A coated composition comprising(a) a core, which is a sold formulation comprises at least one PUFA (and/or salts thereof) and{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, '(b) a coating system according to .'}3. The coated composition according to claim 2 , comprising(a) 70 to 99.5 wt-%, based on the total weight of the composition, of core and(b) 0.5 to 30 wt-%, based on the total weight of the composition, of coating system.4. Process of production of a coated composition according claim 2 , wherein(i) the cores (which comprise PUFA (and/or salts thereof)) are produced by beadlet process, spray drying or spray-granulation in a first step;(ii) these cores (solid particles) are coating in a second step by a solution, dispersion or slurry of the coating material (cyclodextrin), and(iii) afterwards the coated particles are dried.5. Use of the coated particles according to in food products claim 2 , feed products claim 2 , dietary supplements and/or pharmaceutical products.6. Food products claim 2 , feed products claim 2 , dietary supplements and/or pharmaceutical products claim 2 , comprising at least one coated composition according to . The present patent application relates to a novel coating system for coating solid particles, which comprise PUFAs (and/or salts thereof), wherein the coating comprises at least one cyclodextrin. Furthermore it relates to compositions coated with such a coating system and the use of such compositions in the production of food, feed, ...

Solid particles

The present patent application relates to solid particles comprising vitamin A and/or its derivatives, which are more stable when compressed into tablets.

PURGE COMPOSITION AND METHOD OF CLEANING

The invention relates to a purge composition comprising a polymer formulation which is tacky and suitable to cross-link and/or cure to become less tacky, at least 50% of solids of the polymer formulation comprising a polysiloxane, polyurethane, acrylate resin, epoxy resin, melamine resin, formaldehyde resin, or a mixture of two or more of any of these; and a curing catalyst suitable to cure the polymer formulation, wherein the composition is suitable to cross-link and/or cure at within 0.1 to 120 minutes at a temperature in a range of from 0 to 450° C. within a device into which the composition is injected. The invention also relates to a method of cleaning a material processing device. 1. A purge composition , comprising:a polymer formulation which is tacky and suitable to cross-link and/or cure to become less tacky, at least 50% of solids of the polymer formulation comprising a polysiloxane, polyurethane, acrylate resin, epoxy resin, melamine resin, formaldehyde resin, or a mixture of two or more of any of these; anda curing catalyst suitable to cure the polymer formulation,wherein the composition is suitable to cross-link and/or cure at within 0.1 to 120 minutes at a temperature in a range of from 0 to 450° C. within a device into which the composition is injected.2. The composition of claim 1 , wherein the polymer formulation is thermosetting.3. The composition of claim 1 , wherein the polymer formulation comprises a polysiloxane with a Min a range of from 15 to 45 kDa and a polydispersity index in the range of from 3 to 4.5.4. The composition of claim 1 , wherein the polymer formulation comprises a polysiloxane with a Min a range of from 15 to 45 kDa and a polydispersity index in the range of from 1.8 to 3.5. The composition of claim 1 , wherein the polymer formulation comprises a first component which cures at a temperature in a range of from 15 to 30° C. within 10 minutes.6. The composition of claim 1 , wherein the polymer formulation comprises a second ...

System and method for facilitating intranasal guidance

A sphenocath including a sheath assembly including a sheath hub with a sheath tube extending therefrom with a passage extending from a proximal end of the sheath hub to a distal end of the sheath tube; a catheter assembly including a catheter hub with a catheter tube extending therefrom with a passage extending from a proximal end of the catheter hub to a distal end of the catheter tube; wherein the catheter assembly passes through the sheath assembly with a portion of the catheter hub engaging a portion of the sheath hub to limit relative rotation between the hubs while permitting relative axial movement such that in an initial non-extended position the distal end of the catheter tube is proximate to the distal end of the sheath tube. A system further including a guidewire is also provided. A method of inserting the catheter tube is also provided.

CAPSULES CONTAINING THYMOQUINONE

This invention relates to stable capsule formulations for pharmaceutical, nutraceuticals or food supplements which contain thymoquinone (THQ) as an active ingredient, and which can be stored at room temperature without significant loss of THQ during the shelf life of the capsules. The preferred capsules have a hydroxypropylmethylcellulose (HPMC) shell and may contain carvacrol as an additional active ingredient, either in synthetic form, or as part of a plant extract. Optionally, the capsules may contain a viscosity agent. 1. A capsule comprising:a) shell selected from the group consisting of: hydroxypropylmethylcellulose (HPMC), pullulan, and gelatin;b) a fill composition comprising at least 2 weight % thymoquinone (THQ), preferably from 2-8 weight % thymoquinone;c) a diluent selected from the group consisting of: middle chain triglycerides, glycerol, edible vegetable waxes; plant oils (for example: olive oil, palm oils, sunflower oils, maize/corn oil, soybean oil, sesame oil, or rice bran oil), and mixtures thereof; andd) a viscosity increasing agent, with the proviso that the viscosity increasing agent is not phosphaditylcholine, and with the further proviso that when the shell is pullulan or gelatin, then the viscosity increasing agent comprises neither phosphatidylcholine nor lecithin.2. A capsule according to wherein the THQ is stable at room temperature.3. A capsule according to wherein THQ is present in a plant extract.4. A capsule according to wherein the THQ is present in an oregano extract.5. A capsule according to wherein the fill composition further comprises carvacrol (CRV).6. A capsule according to wherein the CRV is at least 30 weight-% of carvacrol claim 5 , preferably at least 50 weight-% of carvacrol claim 5 , more preferably at least 60 weight-% of carvacrol claim 5 , and most preferably least 65 weight-% of carvacrol.7. A capsule according to wherein the shell is HPMC.8. A capsule according to wherein the diluent is middle chain triglycerides.9. ...

Universal solenoid driver

A device may include a driver integrated circuit (IC) comprising a first control unit and a second control unit, a first solenoid that is electrically coupled to the first control unit, a second solenoid that is electrically coupled to the second control unit; at least one sensor, a clock that synchronizes a microcontroller and the driver IC, and a peripheral bus that communicatively couples the first control unit, the second control unit. The microcontroller and the driver IC form an outer control loop that actuates the first solenoid and the second solenoid, and the first control unit, the second control unit, and the at least one sensor form an inner control loop that controls the first solenoid and the second solenoid.

PROCESS FOR THE PRODUCTION OF COMPRESSED TABLETS

The present patent application relates a process for the production of compressed tablets using specific coated particles, wherein the coating (system) comprises at least one wax and/or at least one fat. Furthermore it relates to compressed (compacted) tablets and as well as to specific coated particles. 1. A compressed tablet comprising:(a) 0.1-40 wt. %, based on the total weight of the compressed tablet, of a compressed powder composition comprising coated particles, and(b) 60-99.9 wt. %, based on the total weight of the compressed tablet, of at least one additional ingredient, excipient and/or auxiliary agent selected from the group consisting of fillers, acidity regulators, anti-adherents, dyes, flavours and sweeteners, wherein (i) 40 wt. %-95 wt. % based on the total weight of the coated particle, of a core comprising at least one active ingredient, and', '(ii) 5 wt. %-60 wt. %, based on the total weight of the coated particle, of a coating system present as a coating on the core, wherein the coating system comprises at least one wax and/or at least one fat., 'the coated particles comprise2. The compressed tablet according to claim 1 , whereinthe core comprises at least one active ingredient selected from the group consisting of vitamins A, D, E, and K, and whereinthe coating system comprises at least one wax and/or at least one fat selected from the group consisting of glycerine monostearate, carnauba wax, candelilla wax, sugarcane wax, palmitic acid, stearic acid, at least partially hydrogenated cottonseed oil, at least partially hydrogenated palm oil and at least partially hydrogenated rapeseed oil.3. The compressed tablet according to claim 1 , wherein the compressed powder composition is compressed with a pressure of at least 5 kN.4. The compressed tablet according to claim 3 , wherein the compressed powder composition is compressed with a pressure of 5 kN-40 kN.5. The compressed tablet according to claim 1 , wherein the compressed tablet comprising the ...

METHOD FOR OPERATING A DEVICE FOR ADDITIVE MANUFACTURE OF A THREE-DIMENSIONAL OBJECT

A method for operating a manufacturing device for the additive manufacture of a three-dimensional object, by the layered application and selective solidification of a building material in a building area lying in a working surface, includes directing, by a first scanning unit of the manufacturing device, a detection region of a first sensor unit onto at least one first partial region of a test body region without the first scanning unit directing a beam onto the test body region. The first sensor unit is assigned to the first scanning unit. The method further includes irradiating at least part of the test body region with a beam directed onto the test body region by a second scanning unit of the manufacturing device and evaluating measurement signals detected by the first sensor unit. 1. A method for operating a manufacturing device for the additive manufacture of a three-dimensional object by the layered application and selective solidification of a building material in a building area lying in a working surface , the method comprising:directing, by a first scanning unit of the manufacturing device, a detection region of a first sensor unit onto at least one first partial region of a test body region without the first scanning unit directing a beam onto the test body region, the first sensor unit being assigned to the first scanning unit,irradiating at least part of the test body region with a beam directed onto the test body region by a second scanning unit of the manufacturing device, andevaluating measurement signals detected by the first sensor unit,wherein the first and second scanning units of the manufacturing device are designed and arranged to direct a beam of a respective first or second beam source controlled by the respective first or second scanning unit onto different target points on the building area, andwherein the first scanning unit is configured to direct the detection region of the first sensor unit to a target point of the first scanning unit. ...

PROCESS FOR THE PRODUCTION OF COMPRESSED TABLETS

The present patent application relates a process for the production of compressed tablets using specific coated particles, wherein the coating (system) comprises at least one wax and/or at least one fat. Furthermore it relates to compressed (compacted) tablets and as well as to specific coated particles. 1. Process for the production of compressed tablets , wherein coated particles comprising(i) 40 wt-%-95 wt-%, based on the total weight of the coated particle, of a core, comprising at least one active ingredient and(ii) 5 wt-%-60 wt-%, based on the total weight of the coated particle, of a coating system, and said coating system comprises at least one wax and/or at least one fat, are compressed with a pressure of a least 5 kN.2. Process according to wherein a pressure of 5-40 kN is applied.3. Process according to or claim 1 , wherein the coating system comprises at least one wax and/or fat claim 1 , which has a dropping point of from 30 to 85° C. claim 1 , preferably 40 to 70° C.4. Process according to claim 1 , wherein the coating system comprises at least one wax and/or at least one fat chosen from the group consisting of glycerine monostearate claim 1 , carnauba wax claim 1 , candelilla wax claim 1 , sugarcane wax claim 1 , palmitic acid claim 1 , stearic acid claim 1 , (fully) hydrogenated cottonseed oil claim 1 , (fully) hydrogenated palm oil claim 1 , and (fully) hydrogenated rapeseed oil.5. Process according to claim 1 , wherein the coated particle comprises 50 wt-%-90 wt-% claim 1 , based on the total weight of the coated particle claim 1 , of core and 10 wt-%-50 wt-% claim 1 , based on the total weight of the coated particle claim 1 , of coating system.6. Process according to claim 1 , wherein the core comprises at least one active ingredient chosen form the group consisting of vitamins claim 1 , carotenoids claim 1 , minerals and plant extracts.7. Process according to claim 6 , wherein the core comprises at least one active ingredient chosen form the ...

NOVEL COATING SYSTEM

The present patent application relates to a novel coating system, wherein the coating comprises Carnauba wax and at least one polysorbate. Furthermore it relates to compositions coated with such a coating system and the use of such compositions in the production of tablets. 2. Coating system according to claim 1 , comprising 5-45 wt-% claim 1 , based on the total weight of the coating system claim 1 , of at least one compound of formula (I).3. Coating system according to claim 1 , comprising 5-40 wt-% claim 1 , based on the total weight of the coating system claim 1 , of at least one compound of formula (I).4. Coating system according to claim 1 , comprising 5-30 wt-% claim 1 , based on the total weight of the coating system claim 1 , of at least one compound of formula (I).5. Coating system according to claim 1 , comprising 5-20 wt-% claim 1 , based on the total weight of the coating system claim 1 , of at least one compound of formula (I).6. Coating system according to claim 1 , comprising 55-95 wt-% claim 1 , based on the total weight of the coating system claim 1 , of Carnauba wax.7. Coating system according to claim 1 , comprising 60-95 wt-% claim 1 , based on the total weight of the coating system claim 1 , of Carnauba wax.8. Coating system according to claim 1 , comprising 70-95 wt-% claim 1 , based on the total weight of the coating system claim 1 , of Carnauba wax.9. Coating system according to claim 1 , comprising 80-95 wt-% claim 1 , based on the total weight of the coating system claim 1 , of Carnauba wax.10. Coating system according to claim 1 , wherein the compound of formula (I) is chosen from the group consisting of polysorbate 20 claim 1 , polysorbate 60 and polysorbate 80.11. A particle coated with a coating system according to .12. Coated particle according to claim 11 , wherein the coated particle consists of 40-95 wt-% claim 11 , based on the total of the coated particle claim 11 , of core and 5-60 wt-% claim 11 , based on the total weight of ...

Process of production of a formulation comprising physiologically active inorganic metal salts

This invention relates to a process for producing solid formulations. These solid formulations comprise physiologically active inorganic metal salts, which are known for being bad-tasting. These new solid formulation are neutral in taste. Furthermore the present invention relate to these solid formulations as well as to their use in the production of food, feed, nutritional supplement and personal care products.

SYSTEM WITH OIL FILLING DEVICE FOR A TRANSMISSION

A system includes an oil filling device for a transmission, the transmission having a recess. The oil filling device includes a slotted bushing which is provided with an axially uninterrupted recess through which a cone unit projects, the cone unit having an external thread onto which a nut is screwed, on the side of the slotted bushing facing away from the transmission. The cone unit includes a region that widens in the direction of the transmission, and/or a cone region which presses the slotted bushing against the transmission, in particular in the axial region covered by the recess. 115-. (canceled)16. An oil filling device for a transmission having a recess , comprising:a cone unit;a slotted bushing including an axially uninterrupted recess through which the cone unit projects; anda nut screwed onto an external thread of the cone unit, the external thread located on a side a side of the slotted bushing facing away from the transmission;wherein the cone unit includes a region that widens in a direction of the transmission and/or a conical region that presses the slotted bushing against the transmission and/or an axial region covered by the recess of the transmission;wherein the cone unit is axially displaceable as a function of a rotary position of the nut, the slotted bushing adapted to press against the recess of the transmission by the cone unit; andwherein the cone unit includes a conical bushing and a threaded sleeve firmly connected to the conical bushing or is arranged as one piece.17. The oil filling device according to claim 16 , wherein the slotted bushing includes slots set apart from one another in a circumferential direction and cover an axial region that overlaps with the axial region covered by the recess of the transmission or that encompasses the axial region covered by the recess of the transmission claim 16 , the slots being set apart from one another at regular intervals in the circumferential direction.18. The oil filling device according to ...

VITAMIN FORMULATION

The present patent application relates to solid particles comprising at least one fatsoluble vitamin, which are more stable when compressed into tablets. 1. Solid particles comprising(i) at least 20 wt-%, based on the total weight of the solid particles, of least one fat soluble vitamin,(ii) at least one emulsifier, and(iii) at least one non-reducing sugar.2. Solid particles according to comprising5-55 weight-% (wt-%), based on the total weight of the solid particle, of at least one non-reducing sugar (preferably trehalose).3. Solid particles according to comprising10-50 weight-% (wt-%), based on the total weight of the solid particle, of at least one non-reducing sugar.4. Solid particles according to claim 1 , wherein the fat soluble vitamin is chosen from the group of vitamin A and its derivatives (such as vitamin A acetate or vitamin A palmitate).5. Solid particles according to comprising 20-75 wt-% claim 1 , based on the total weight of the solid particle claim 1 , of at least one fat-soluble vitamin.6. Solid particles according to comprising 25-70 wt-% claim 1 , based on the total weight of the solid particle claim 1 , of at least one fat-soluble vitamin.7. Solid particles according to comprising 20-70 wt-% claim 1 , based on the total weight of the solid particles claim 1 , of at least one emulsifier.8. Solid particles according to claim 1 , wherein the at least emulsifier is chosen from the group consisting of modified (food) starches claim 1 , ascorbyl palmitate claim 1 , pectin claim 1 , alginate claim 1 , carrageenan claim 1 , furcellaran claim 1 , dextrin derivatives claim 1 , celluloses and cellulose derivatives (e.g. cellulose acetate claim 1 , methyl cellulose claim 1 , hydroxypropyl methyl cellulose) claim 1 , lignosulfonate claim 1 , polysaccharide gums (such as gum acacia (=gum arabic) claim 1 , modified gum acacia claim 1 , TIC gum claim 1 , flaxseed gum claim 1 , ghatti gum claim 1 , tamarind gum and arabinogalactan) claim 1 , gelatine (bovine ...

PROCESS OF PRODUCTION OF A FORMULATION COMPRISING THERAPEUTICALLY ACTIVE OR NUTRITIOUS PLANT EXTRACTS

This invention relates to a process for producing solid formulations. These solid formulations comprise therapeutically active or nutritious plant extracts, which are known for being bad-tasting. These new solid formulation are neutral in taste. Furthermore the present invention relate to these solid formulations as well as to their use in the production of food, feed, nutritional supplement and personal care products. 1. Process for the production of a solid formulation comprising(i) 20-40, weight-% (wt-%), based on the total weight of the solid formulation, of least one therapeutically active or nutritious plant extract, and(ii) 60-80 wt-%, based on the total weight of the solid formulation, of at least one lipophilic material, wherein(a) the lipophilic material is added in its liquid state and(b) at least one therapeutically active or nutritious plant extract is suspended the molten lipophilic material, and(c) the suspension is atomized into a spray tower, where the air has such a temperature that the lipophilic material solidifies.2. The process according to claim 1 , wherein the therapeutically active or nutritious plant extract is an Acerola plant extract.3. The process according to claim 1 , wherein the lipophilic material are waxes and fats having a drop point of from 30 to 90° C. claim 1 , preferably 40 to 80° C.4. The process according to claim 1 , wherein the lipophilic material are waxes and fats chosen from the group consisting of glycerine monostearate claim 1 , carnauba wax claim 1 , candelilla wax claim 1 , palmitic acid claim 1 , stearic acid hydrogenated cottonseed oil and hydrogenated rapeseed oil.5. The process according to claim 1 , wherein the lipophilic material is glycerol monostearate.6. The process according to claim 1 , wherein 20-35 wt-% claim 1 , based on the total weight of the solid formulation claim 1 , of least one therapeutically active or nutritious plant extract is used.7. The process according to claim 1 , wherein 65-80 wt-% ...

PROCESS FOR PRODUCING COATED PARTICLES

The present patent application relates to coated particles. These coated particles show improved properties when used in compressed tablets. 2. Process according to claim 1 , wherein the cores are introduced into the top spraying device at room temperature.3. Process according to claim 1 , wherein the inlet temperature kept at a constant temperature.4. Process according to claim 3 , wherein the inlet temperature kept at a constant temperature of 30-60° C.5. Process according to claim 1 , wherein the spraying rate for the molten coating layer compound is kept constant.6. Process according to claim 5 , wherein the spraying rate is 2 g·minup to 8 g·min.7. Process according to claim 1 , wherein an atomizing air pressure of 1 bar and an atomizing air temperature of 100 to 120° C. is used for the entire process.8. Process according to claim 1 , wherein the coating system of the coated particles comprises at least one wax and/or at least one fat claim 1 , which has a dropping point of from 30 to 85° C. claim 1 , preferably 40 to 70° C.9. Process according to claim 1 , wherein the coating system of the coated particles comprises at least one wax and/or at least one fat chosen from the group consisting of glycerine monostearate claim 1 , carnauba wax claim 1 , candelilla wax claim 1 , sugarcane wax claim 1 , palmitic acid claim 1 , stearic acid claim 1 , (fully) hydrogenated cottonseed oil claim 1 , (fully) hydrogenated palm oil and (fully) hydrogenated rapeseed oil.10. Process according to claim 9 , wherein the coating system of the coated particles comprises at least one wax and/or at least one fat chosen from the group consisting of carnauba wax claim 9 , candelilla wax claim 9 , sugarcane wax and (fully) hydrogenated palm oil.11. Process according to claim 1 , wherein the coating system of the coated particles comprises 50 wt-%-90 wt-% claim 1 , based on the total weight of the coated particles claim 1 , of a core and 10 wt-%-50 wt-% claim 1 , based on the total weight ...

Buffer solutions for suspensions used in chemical-mechanical polishing

The present invention relates to buffer systems in the form of solutions or salts for preparing suspensions which can be used for chemomechanical polishing. In particular, these buffer systems can be used for preparing suspensions having a high pH of 9.5-13 which are used for the chemomechanical polishing of Si and metal surfaces of semiconductors, known as wafers.

Buffer solutions for suspensions used in chemical-mechanical polishing

Control system for power train control

Embodiments of the present disclosure relate to methods, system, and devices for synchronizing angular position information between a first and a second semiconductor chip used for engine management in an automobile is described. In accordance with one embodiment, a system for synchronizing angular position information between a first and a second semiconductor chip comprises the first and the second semiconductor chip and a digital real-time communication link connecting the first and the second semiconductor chip. The second semiconductor chip comprise a master angle estimation circuit, which is configured to estimate an angular position of the engine based on at least one angular position sensor signal. The first semiconductor chip comprises a slave angle estimation circuit, which is configured to estimate an angular position of the engine based on information concerning angular position received form the master angle estimation circuit via the communication link.

BUFFER SOLUTIONS FOR SUSPENSIONS, APPLICABLE FOR CHEMICAL-MECHANICAL POLISHING

Metylen-4-azasteroider.

Pivoting dilator

A dilator ( 100 ) for expanding a vessel incision to assist insertion of a catheter thereinto and having a distal end ( 104 ) and a proximal end ( 106 ). The dilator has two portions ( 110,210 ) that are assembled together at a hinge ( 112,212 ) permitting angled-apart proximal ends ( 122,222 ) of the two portions at the proximal end ( 106 ) to be squeezed together about the hinge which slightly spreads apart the respective distal ends ( 114,214 ) of the two portions to enlarge the incision into the vessel. A spring ( 150 ) biases apart the proximal ends of the two portions to maintain the two distal ends ( 114,214 ) together until pried apart as desired to dilate the vessel incision.

Pivoting dilator

A dilator ( 100 ) for expanding a vessel incision to assist insertion of a catheter thereinto and having a distal end ( 104 ) and a proximal end ( 106 ). The dilator has two portions ( 110,210 ) that are assembled together at a hinge ( 112,212 ) permitting angled-apart proximal ends ( 122,222 ) of the two portions at the proximal end ( 106 ) to be squeezed together about the hinge which slightly spreads apart the respective distal ends ( 114,214 ) of the two portions to enlarge the incision into the vessel. A spring ( 150 ) biases apart the proximal ends of the two portions to maintain the two distal ends ( 114,214 ) together until pried apart as desired to dilate the vessel incision.

Luer cleaner

A luer cleaner including a generally hollow body having an open first end, a closed second end, and a longitudinal axis extending therethrough between the first end and the second end. The first end is sized to receive therein a luer connector proximal end and includes a plurality of bristles extending generally toward the longitudinal axis sufficiently to engage the outer surfaces of the luer proximal end disposed therein. The second end comprises a compressible reservoir containing a fluid, wherein, when the second end is compressed, the fluid is transmitted from the reservoir toward the first end through passageways to wet the luer proximal end. A method for cleaning luer connectors is also disclosed.

Buffer solutions for suspensions used in chemical-mechanical polishing

The present invention relates to buffer systems in the form of solutions or the salts thereof for the production of suspensions that can be used in chemical-mechanical polishing. Said buffer systems can be particularly used in the production of suspensions with a high pH value ranging from 9,5 to 13. Said suspensions can be used for chemical-mechanical polishing of silicium and metal surfaces of semiconductors, i.e. wafers.

Venous access port assembly with radiopaque indicia

A venous access port assembly (10) having a housing base (28) with a discharge port (16), a septum (14) and a cap (48). An interior reservoir (22) is defined by a well (30) in the housing base and a bottom (62) of the septum, and a passageway (20) extends from the reservoir through the discharge port (16). The housing base (28) is provided with radiopaque markings (60) on the bottom wall (44) thereof, including radiopaque indicia (70) that identify an attribute of the assembly (10) after its implantation and clearly appear on an X-ray of the patient in a manner informing the radiologist or technologist and the medical practitioner of that particular attribute.

Venous reservoir with molded indications and / or radiopacas

Un conjunto de reservorio venoso (72, 74) para su implantación en un paciente, que comprende: una carcasa que tiene una base (28), que define una pared inferior de al menos un depósito, teniendo adicionalmente la carcasa un orificio de descarga (16) que se extiende desde el al menos un depósito, y teniendo la base una brida (36) adyacente al al menos un depósito, extendiéndose la brida hacia fuera desde la base alrededor de un perímetro del al menos un depósito, e incluyendo indicaciones moldeadas en la misma que indican una característica del conjunto; y un diafragma penetrable por aguja, que se comunica con la carcasa; caracterizado por que la brida comprende un material metálico y las indicaciones están formadas por huecos practicados en la brida, por ejemplo recortados o perforados en la brida, de modo que las indicaciones sean visibles por examen de rayos X cuando el conjunto esté implantado subcutáneamente en un paciente. A venous reservoir assembly (72, 74) for implantation in a patient, comprising: a housing having a base (28) defining a bottom wall of at least one reservoir, the housing further having a discharge port ( 16) extending from the at least one reservoir, and the base having a flange (36) adjacent to the at least one reservoir, the flange extending outwardly from the base around a perimeter of the at least one reservoir, and including molded indicia in the same that indicate a characteristic of the set; and a needle penetrable diaphragm, which communicates with the housing; characterized in that the flange comprises a metallic material and the indicia are formed by recesses made in the flange, for example cut out or perforated in the flange, so that the indicia are visible by X-ray examination when the assembly is implanted subcutaneously in a patient.

Radial-axial ring rolling mill for rolling a ring

Minimising mist formation of flowing test gas - by relaxing pressure in cooled filter cavity with immediate absorption of evolved moisture

Compositions For Enternal Application Of Microorganisms

The present invention describes a process for the manufacture of a solid composition comprising a microorganism, which process comprises a first step of blending and/or compacting the microorganism with a salt of a medium or long-chain fatty acid to prepare a powderous mixture or compacted granulate, and a second step of providing said powderous mixture or compacted granulate with a coating. The microorganisms are preferably probiotics. The invention also relates to the solid composition obtained by said process and to its use in food.

Elastic fixing device for fixing a housing to an internal combustion engine with vibration decoupling.

PNEUMATIC SPRING

Relative spin speed traction control

An apparatus for providing relative spin speed traction control on a railway vehicle. Such apparatus includes a wheel spin detection device connected to receive a plurality of input signals; one of such input signals being an externally generated axle rate signal which represents an acceleration/deceleration rate of a particular wheel/axle set being monitored with respect to wheel slippage. This device generates a spin speed selection output signal and a respective axle's wheel spin detection signal. A wheel spin correction device connected to receive as input signals; a power/brake signal which represents when such vehicle is either in a braking mode or not, a spin speed selection output signal and the respective axle's wheel spin detection signal. This device determines the appropriate output force command signal selected from remove, hold and apply and also generates an output signal indicating a spin correction being in progress or not in progress for a respective axle. A wheel spin axle force command signal generating unit connected to receive a power/brake signal, an output force command signal and a signal indicative of spin correction, for generating a re-application jerk limiting output signal and communicating this signal to respective truck 1 and truck 2 propulsion control units. A speed normalization unit connected to receive raw axle speed signals, a power/brake signal, axle rate signals and an output signal representative of car level spin for generating an output signal representative of normalized axle speed.

PNEUMATIC SHOCK ABSORBER

AMORTISSEUR PNEUMATIQUE POUR SUPPORTER UN CORPS EN VIBRATION SUR UNE FONDATION, COMPRENANT UN COUSSIN PNEUMATIQUE AVEC UNE ENCEINTE INTERIEURE VARIABLE 13, QUI EST RACCORDE A UN RESERVOIR A GAZ SOUS PRESSION PAR UNE CONDUITE 2 COMPORTANT AU MOINS UNE VANNE D'ENTREE DE GAZ 11 ET UNE VANNE DE SORTIE DE GAZ 1, COMPRENANT CHACUNE UN SIEGE DE VANNE ET UN ELEMENT DE REGLAGE APPLIQUE ELASTIQUEMENT, AU MOINS UN PISTON DE REGLAGE 3 SOUMIS, SUR SA FACE ANTERIEURE, A LA PRESSION DE L'ENCEINTE INTERIEURE 13 ETANT PREVU POUR ASSURER L'OUVERTURE D'AU MAXIMUM L'UNE DES DEUX VANNES, 1, 11, CE PISTON 3 POUVANT COULISSER DANS UN BOITIER 19 DANS LA MEME DIRECTION QUE LES ELEMENTS DE REGLAGE, LE SIEGE DE LA VANNE D'ENTREE DE GAZ 11 ETANT CONSTITUE PAR LE BOITIER 19, LES ELEMENTS DE REGLAGE DE LA VANNE D'ENTREE DE GAZ 11 ET DE LA VANNE DE SORTIE DE GAZ 1 ETANT RELIES ENTRE EUX, LE SIEGE DE LA VANNE DE SORTIE DE GAZ 1 ETANT CONSTITUE PAR LA FACE ANTERIEURE DU PISTON DE REGLAGE 3, LA CONDUITE CORRESPONDANTE DE MISE A L'AIR PASSANT A TRAVERS LE PISTON DE REGLAGE 3, POUR DEBOUCHER DANS L'ATMOSPHERE ET LE PISTON DE REGLAGE 3 ETANT APPUYE, PAR SA FACE POSTERIEURE, SUR UN RESSORT A PRESSION 14. PNEUMATIC SHOCK ABSORBER FOR SUPPORTING A VIBRATION BODY ON A FOUNDATION, INCLUDING A PNEUMATIC CUSHION WITH A VARIABLE INTERIOR ENCLOSURE 13, WHICH IS CONNECTED TO A PRESSURIZED GAS TANK BY A DUCT 2 WITH AT LEAST ONE VALVE 11 AND GAS INLET GAS OUTLET VALVE 1, EACH INCLUDING A VALVE SEAT AND AN ELASTICALLY APPLIED ADJUSTING ELEMENT, AT LEAST ONE ADJUSTING PISTON 3 SUBJECT, ON ITS ANTERIOR FACE, TO THE PRESSURE OF THE INTERNAL ENCLOSURE 13, PROVIDED FOR TO ENSURE THE OPENING AT MAXIMUM ONE OF THE TWO VALVES, 1, 11, THIS PISTON 3 CAN SLIDE IN A BOX 19 IN THE SAME DIRECTION AS THE ADJUSTING ELEMENTS, THE SEAT OF THE GAS INLET VALVE 11 BEING CONSTITUTED BY THE BOX 19, THE ADJUSTING ELEMENTS OF THE GAS INLET VALVE 11 AND OF THE GAS OUTLET VALVE 1 BEING CONNECTED WITH THEM, ...

MEDICAMENT BASED ON A COMBINATION OF AN AROMATASE INHIBITOR AND AN ANTI-ANDROGEN, USEFUL FOR THE TREATMENT AND PREVENTION OF PROSTATE HYPERPLASIA

A combination of an aromatase-inhibitor and an antiandrogen in a weight ratio of aromatase-inhibitor to antiandrogen of 20:1 to 1:1 is useful in a method of prophylaxis and/or of treatment by therapy of prostatic hyperplasia. The aromatase-inhibitor is, for example, testolactone and the antiandrogen is, for example, cyproterone acetate.

MULTI-PATH DISCRIMINATOR MODULE FOR A NAVIGATION SYSTEM

The invention concerns a multipath discriminator module for a communication and/or navigation system using distributed spectrum modulation, comprising an input for receiving navigation signals, a sampler for supplying sampling signals at a frequency twice the apparent frequency fc of the code of said signals, and a sub-module for calculating an error signal ek from said sampled signals and a locally generated distribution code C/K/L. The invention is characterised in that the sub-module uses the calculation of the real part of a ratio of two correlation values early relative to the real phase value, said values being derived from a correlation between the received signal and a locally generated reference code signal.

PNEUMATIC SPRING

L'INVENTION CONCERNE UN RESSORT PNEUMATIQUE. CE RESSORT COMPREND UN SOUFFLET FLEXIBLE 3 COMPORTANT UN COMPARTIMENT INTERIEUR REMPLI D'AIR QUI, AU BESOIN, PEUT ETRE RACCORDE, PAR UNE SOUPAPE DE REGLAGE 4, A UN RESERVOIR DE GAZ COMPRIME 17 OU A L'ATMOSPHERE. LA SOUPAPE DE REGLAGE EST ACTIONNEE PAR UN PISTON DE REGLAGE 5 QUI EST SOLLICITE, SUR SA FACE AVANT, PAR LA PRESSION INTERNE DU SOUFFLET FLEXIBLE ET, SUR SA FACE ARRIERE, PAR UN COUSSIN DE GAZ A PRESSION VARIABLE CONTENU DANS UNE CHAMBRE A PRESSION 6, CE PISTON ASSURANT UNE COMPENSATION DES FLUCTUATIONS DE PRESSION SURVENANT DANS LE SOUFFLET FLEXIBLE SOUS L'EFFET DES OSCILLATIONS, PAR UNE ALIMENTATION SUPPLEMENTAIRE OU PAR L'EXPULSION D'AIR PRECOMPRIME. LE RESSORT PNEUMATIQUE DE L'INVENTION EST UTILISE POUR SOUTENIR UN CORPS OSCILLANT SUR UNE SEMELLE. THE INVENTION RELATES TO A PNEUMATIC SPRING. THIS SPRING INCLUDES A FLEXIBLE BELLOWS 3 INCLUDING AN INTERIOR COMPARTMENT FILLED WITH AIR WHICH, IF NECESSARY, CAN BE CONNECTED, BY AN ADJUSTING VALVE 4, TO A COMPRESSED GAS TANK 17 OR TO THE ATMOSPHERE. THE ADJUSTING VALVE IS ACTUATED BY AN ADJUSTING PISTON 5, ON ITS FRONT SIDE, BY THE INTERNAL PRESSURE OF THE FLEXIBLE BELLOWS AND, ON ITS REAR SIDE, BY A VARIABLE PRESSURE GAS CUSHION CONTAINED IN A PRESSURE CHAMBER 6 , THIS PISTON ENSURES COMPENSATION FOR THE PRESSURE FLUCTUATIONS OCCURRING IN THE FLEXIBLE BELLOWS DUE TO OSCILLATION, BY AN ADDITIONAL SUPPLY OR BY THE EXHAUST OF PRECompressed air. THE PNEUMATIC SPRING OF THE INVENTION IS USED TO SUPPORT AN OSCILLATING BODY ON A SOLE.

PNEUMATIC SHOCK ABSORBER

Huber needle assembly with safety capture device.

Un montaje de aguja Huber con dispositivo de captura de seguridad incluye al menos un cuerpo, una aguja y un brazo movible. El brazo movible es pivotable con relación al cuerpo e incluye una cubierta de captura en un extremo distal del mismo. La cubierta de captura es cilíndrica, incluye una pared lateral perimetral que tiene una cara exterior y una cara interior y tiene extremo proximal abierto. La cubierta de captura incluye una ranura a través de la pared lateral perimetral, que proporciona acceso en una cámara interna definida por la pared lateral perimetral. La ranura se extiende longitudinalmente sobre al menos una porción de la longitud de la cubierta de captura y al menos una porción de la ranura tiene un ancho menor que el diámetro exterior de la aguja para capturar una punta de la aguja en la misma cuando el brazo movible pivotea a una posición de captura de seguridad.

Shaft straightening and hardening machine

Beschrieben wird eine Wellenricht- und -härtemaschine mit einer Aufnahme für ein wellenförmiges Werkstück, welche um eine zur Achse des Werkstückes im wesentlichen parallele Achse drehbar gelagert ist, mit einem gesteuerten Drehantrieb für die Aufnahme und einem Kühlmittelbad, welches die Aufnahme auf einem Teil ihres Drehweges durchläuft, sowie mit wenigstens einem an einer vorgegebenen Stelle der Länge des Werkstückes angeordneten Richtmittel, welches das Werkstück radial beaufschlagt und zum Be- und Entladen des Werkstückes von diesem abschwenkbar ist. Für eine Verbesserung dieser Maschinenart ist vorgesehen, daß die Aufnahme mehrere parallele Richtwellen aufweist, zwischen welche das Werkstück einfügbar und aus denen entnehmbar ist, wobei jede Richtwelle an ihren Stirnseiten in je einem Lagerbock gehalten und eine der Richtwellen radial abschwenkbar ist, und wobei die Richtwellen radial vorstehende Profilierungen als Richtmittel aufweisen. A shaft straightening and hardening machine is described with a receptacle for a wave-shaped workpiece, which is rotatably mounted about an axis substantially parallel to the axis of the workpiece, with a controlled rotary drive for the receptacle and a coolant bath, which takes the receptacle over part of its rotation path passes, as well as with at least one straightening means arranged at a predetermined point on the length of the workpiece, which acts radially on the workpiece and can be pivoted away from the workpiece for loading and unloading. To improve this type of machine, it is provided that the receptacle has a plurality of parallel straightening shafts, between which the workpiece can be inserted and removed, from which each straightening shaft is held on its end faces in a bearing block and one of the straightening shafts can be pivoted radially, and the straightening shafts have radially projecting profiles as a straightening means.

Catheter

The invention relates to a catheter for the flow of fluids, consisting of a plastic tube with at least one distal connection piece. Such catheters are used, for example, for connecting, to the body of the patient, the metering unit of an infusion apparatus which can be carried on the human body. According to the invention, the plastic tube (1, 101, 201) is enclosed by a further tube (3, 103, 203) as protection against buckling. In a first embodiment of the invention, only that area of the plastic tube (1) directed towards the connection piece (2) is enclosed by the further tube (3). In further embodiments of the invention, the outer tube (103) extends over the length of the whole of the inner catheter tube (101), or the outer tube (203) is longer than the inner catheter tube (101). <IMAGE>

Elastic bearing with top and support bearing esp. for motors

The spring body (5, 2) pressure-loaded by the bearing's static initial load is in two parts and consists of an annular, elastomeric spring element (14, 2) and a series connected stack (15. 2) of at least two plate springs. The end side (16) of the spring element (14, 2, 14, 1) facing the stack of plate springs has a reinforcement (17) partly enclosing the periphery of the stack of plate springs in the direction of the oscillations introduced. The reinforcement restricting the relative deflection movements of the support bodies (8) and housing (9) is in the form of a bumper (18). the reinforcement is in the form of a pot-shaped sheet metal ring stuck to the adjacent spring element.

Universal wheel slip force control logic

A method in part enables a wheel slip control system that controls slip on a per axle basis to control slip on a per truck basis. The wheel slip control system issues on a per axle basis an axle reduction signal indicative of a percentage by which to reduce the braking force that would normally be applied to one wheel/axle combination on a truck of a rail vehicle. The method includes the step of converting the axle reduction signals issued on a per axle basis to a truck reduction priority signal indicative of a percentage by which to reduce the braking force on a per truck basis. For rail vehicles featuring dynamic braking equipment another step involves commanding the dynamic braking equipment to reduce the dynamic braking force being applied to the wheel/axle combinations of the truck in response to the percentage carried by the truck reduction priority signal. Still another step involves commanding the friction braking equipment to apply an appropriate amount of friction braking force to the wheel/axle combinations of the truck so as to resolve the slip experienced thereby. The appropriate amount of friction braking force represents the sum of the total braking force sought to be applied to the wheel/axle combinations of the truck less first a product of the total braking force and the percentage carried by the truck reduction priority signal and less second the dynamic braking force being applied to the wheel/axle combinations of the truck.

Pivoting dilator

A dilator (100) for expanding a vessel incision to assist insertion of a catheter thereinto and having a distal end (104) and a proximal end (106). The dilator has two portions (110, 210) that are assembled together at a hinge (1 12, 212) permitting angled-apart proximal ends (122, 222) of the two portions at the proximal end (106) to be squeezed together about the hinge which slightly spreads apart the respective distal ends (114, 214) of the two portions to enlarge the incision into the vessel. A spring (150) biases apart the proximal ends of the two portions to maintain the two distal ends (114, 214) together until pried apart as desired to dilate the vessel incision.

Coaxial sharpened catheter

Un catéter coaxial que comprende: a) un primer lumen que se extiende a lo largo de un eje, en el que el primer lumen tiene un primer extremo distal abierto y un primer extremo proximal; b) un segundo lumen que se extiende a lo largo del eje, en el que el segundo lumen está dispuesto generalmente dentro del primer lumen, y en el que el segundo lumen incluye un segundo extremo distal que se extiende distalmente del primer extremo distal; y c) al menos un espaciador dispuesto entre el primer lumen y el segundo lumen en el extremo distal del primer lumen. A coaxial catheter comprising: a) a first lumen that extends along an axis, in which the first lumen has a first open distal end and a first proximal end; b) a second lumen that extends along the axis, in which the second lumen is generally disposed within the first lumen, and in which the second lumen includes a second distal end that extends distally from the first distal end; and c) at least one spacer arranged between the first lumen and the second lumen at the distal end of the first lumen.

Combined picture and writing desk - has base to accommodate typewriter and raised rear wall for clock

PROCEDURE FOR FRAMSTAELLNING AV 6-METHYL-3,4-DIHYDRO-1,2,3-OXATIAZIN-4-ON-2,2-DIOXIDE OCH RENING AV DENSAMMA.

Catheter infusion port

A port ( 100 ) for a catheter assembly ( 200 ), including a body ( 102 ) and a cover ( 150 ) and having a distal discharge port ( 116 ) for connection to an implanted catheter assembly. Within the body is a longitudinal U-shaped channel ( 120 ) extending to a proximal body wall ( 104 ) from the distal body wall ( 106 ) along a longitudinal axis parallel to the axis of the discharge port ( 116 ). The channel has a rounded bottom ( 122 ) and is also rounded at the channel ends ( 126,124 ) at the distal and proximal body walls. The cover ( 150 ) provides for penetration by a syringe needle and seals upon needle withdrawal, with the cover having an inside surface ( 152 ) concave and rounded between the distal and proximal ends and also longitudinally, being generally smoothed into the channel sides and ends. The port has no inner sharp edges or corners and eliminates blood clotting and unwanted growth sites.

Tube transfer device in a tube filling machine and method for its control

Eine Tuben-Umsetzvorrichtung in einer Tubenfüllmaschine weist einen 1. Förderer, mit dem die Tuben in Form eines Tuben-Gebindes einen Zwischenlagerplatz zuführbar sind, und eine Umsetzvorrichtung auf, mit der die Tuben von dem Zwischenlagerplatz auf einen weiterführenden 2. Förderer ablegbar sind. Die Umsetzvorrichtung weist einen Roboter mit schwenkbaren Armen und einer Greifvorrichtung zum Ergreifen einer oder mehrerer Tuben auf. Dabei ist vorgesehen, dass der Roboter ein kollaborativer Roboter (Cobot) ist und dass eine Sensorvorrichtung vorgesehen ist, mittels der ein den Cobot enthaltende Raum hinsichtlich der Anwesenheit eines Lebewesens überwachbar ist. Wenn die Sensorvorrichtung in dem überwachten Raum ein Lebewesen feststellt, wird die Arbeitsgeschwindigkeit der Tuben-Umsetzvorrichtung auf einen Wert >0 Tuben/min verringert, jedoch nicht abgeschaltet. A tube transfer device in a tube filling machine has a first conveyor, with which the tubes in the form of a tube container an intermediate storage space can be fed, and a transfer device with which the tubes can be stored from the intermediate storage space on a secondary second conveyor. The transfer device comprises a robot with pivotable arms and a gripping device for gripping one or more tubes. It is provided that the robot is a collaborative robot (Cobot) and that a sensor device is provided, by means of which a space containing the cobot can be monitored with regard to the presence of a living being. When the sensor device detects a subject in the monitored room, the operating speed of the tube translator is reduced to a value> 0 tubes / min, but not turned off.

Using delta opioid receptor agonists in the field of cosmetics and dermocosmetics.

La présente invention concerne l’utilisation d’un ligand des ROD pour la stimulation de la pigmentation dans une composition cosmétique et l’utilisation de rubiscoline 6 ou de ses dérivés dans une composition cosmétique. The present invention relates to the use of an ROD ligand for the stimulation of pigmentation in a cosmetic composition and the use of rubiscoline 6 or its derivatives in a cosmetic composition.

Method for Expanding a Vessel

A cutting balloon catheter assembly ( 100 ) including a dual lumen catheter ( 130 ) having a distal end ( 134 ), an inflation/deflation lumen ( 138 ) and a second or guidewire lumen ( 136 ). The assembly further includes an inflatable balloon ( 110 ) having an interior cavity ( 116 ) and an expandable covering ( 120 ) disposed about the balloon wherein the covering has an array of cutting edges. In the assembly, the balloon ( 110 ) is fixedly connected to the distal end ( 134 ) of the catheter and the interior cavity ( 116 ) of the balloon ( 110 ) is in fluid communication with the first lumen ( 138 ) of the catheter ( 130 ). A method of removing obstructions ( 149 ) from vessel walls ( 154 ) using the present invention is also disclosed wherein the cutting edges abrade the stenoses, plaque or lesions along the vessel walls, when the catheter assembly is reciprocally moved longitudinally or rotationally after inflation of the balloon.

Venous access port assembly with radiopaque indicia

A venous access port assembly ( 10 ) having a housing base ( 28 ) with a discharge port ( 16 ), a septum ( 14 ) and a cap ( 48 ). An interior reservoir ( 22 ) is defined by a well ( 30 ) in the housing base and a bottom ( 62 ) of the septum, and a passageway ( 20 ) extends from the reservoir through the discharge port ( 16 ). The housing base ( 28 ) is provided with radiopaque markings ( 60 ) on the bottom wall ( 44 ) thereof, including radiopaque indicia ( 70 ) that identify an attribute of the assembly ( 10 ) after its implantation and clearly appear on an X-ray of the patient in a manner informing the radiologist or technologist and the medical practitioner of that particular attribute.

Air pressure spring

A gas pressure spring for the mutual support of two oscillating elements moving relative to one another, in which first and second auxiliary means (1, 2), which are controlled by sensors (9, 10) and effect the blowing off of excess pressure gas from the gas pressure spring or the feeding of additional pressure gas into the gas pressure spring (11) by the actuation of valves (3, 4, 5) are provided. In order to avoid mutual impairment of functioning, the first auxiliary means (1) is only effective in the case of pressure changes at a frequency above a threshold value and the second auxiliary means (2) is only effective in the case of changes in the relative association of the two elements (7, 8) at a frequency below the threshold value. <IMAGE>

Gastric inflation band with integrated infusion catheter

An inflatable gastric band incorporates a fluid channel within an outer surface of the band and an inflatable bladder on a stomach-faeing side of the band. The gastric band attaches to a double lumen catheter, whieh com-municates with a dual infusion port. One lumen communicates with the fluid channel and one port, while the other lumen communicates with the inflatable bladder and a second port. Injection of fluid into one chamber of the infu-sion port expands inflatable bladder, allowing adjustment to the diameter of the stoma. Injection of drugs or therapeutic agents into the second chamber al-lows the infusion of drugs or agents directly into the abdominal cavity of a gas-tric band recipient. The inflatable bladder can be eontinuous or segmented. A segmented bladder reduces pinching and/or folding of the inner surface of the gastric band during expansion/contraction, thereby lessening stomach pinch-ing and/or irritation.

Luer cleaner

A luer cleaner (100) including a generally hollow body (112) having an open first end (104), a closed second end (106), and a longitudinal axis extending therethrough between the first end and the second end. The first end (104) is sized to receive therein a luer connector (190) proximal end and includes a plurality of bristles (134) extending generally toward the longitudinal axis sufficiently to engage the outer surfaces of the luer proximal end disposed therein. The second end comprises a compressible reservoir (166) containing a fluid (168), wherein, when the second end is compressed, the fluid is transmitted from the reservoir toward the first end through passageways to wet the luer proximal end. A method for cleaning luer connectors is also disclosed.

METHOD OF PREPARING NON-TOXIC SALTS OF 6-METHYL-3,4-DIHYDRO-1,2,3-OXATHIAZIN-4-ON-2,2-DIOXIDE

Magnet cuff for vascular catheters and bloodlines

A catheter having a catheter body having a proximal end and a distal end and a proximal portion fixedly connected to the proximal end is disclosed. A magnet is disposed around the catheter body distally of the proximal portion.

Splittable multiple catheter assembly

A multiple catheter assembly including a first catheter constructed from a first material and having a first proximal end region, a first distal end region terminating in a first distal tip, and an outer surface defining at least a first lumen extending longitudinally therethrough between a first distal and a first proximal opening. The first proximal end region is integrally connected to an extension tube constructed from a second material. A second catheter is constructed from the first material and having a second proximal end region, a second distal end region terminating in a second distal tip, and a second outer surface defining at least a second lumen extending longitudinally therethrough between a second distal and a second proximal opening. The second proximal end region is integrally connected to an extension tube constructed from the second material. The first lumen and the second lumen are independent from each other for facilitating simultaneous flow in opposite directions. The outer surfaces of the first and second catheters are releasably joined for allowing the first and second distal tips to be at least partially longitudinally split from each other.

Releasably locking dilator and sheath assembly

A releasably locking dilator and sheath assembly (10, 200, 300) and methods for releasing the dilator (12) from and longitudinally splitting the sheath (14). The assembly includes a dilator having a dilator hub (20) and a sheath having a sheath hub (40, 240). The sheath hub has a valve (260, 360) and two opposing winged tabs (42), each tab having a perpendicular portion (44) and an angled portion (46), as well as having a female locking portion (53). The dilator hub has a male locking portion (30) designed to engage the female locking portion of the sheath hub. The dilator is released from the sheath by rotating the dilator 90° in relation to the sheath and pulling the dilator out of the sheath. The sheath is longitudinally split by creating a couple on each of the winged tabs (42) thereby forcing the sheath and the sheath hub to split longitudinally.

Venous access port assembly with radiopaque indicia

A venous access port assembly (10) having a housing base (28) with a discharge port (16), a septum (14) and a cap (48). An interior reservoir (22) is defined by a well (30) in the housing base and a bottom (62) of the septum, and a passageway (20) extends from the reservoir through the discharge port (16). The housing base (28) is provided with radiopaque markings (60) on the bottom wall (44) thereof, including radiopaque indicia (70) that identify an attribute of the assembly (10) after its implantation and clearly appear on an X-ray of the patient in a manner informing the radiologist or technologist and the medical practitioner of that particular attribute.

APPLICATION OF THE COMBINATION OF AN AROMATAS INHIBITOR WITH AN ANTI-DRUG AGENT FOR PROPHYLAX AND THERAPY OF PROSTATE HYPERAPLASIA

PROCEDURE FOR THE PREPARATION OF 6-METHYL-3,4-DIHYDRO-1,2,3-OCSATIAZIN-4-ON-2,2-DIOXYDIC AND ITS PURIFICATION.

METHOD FOR PRODUCING 6-METHYL-3,4-DIHYDRO-1,2,3-OXATHIAZINE-4-ON-2,2-DIOXIDE

Stable carotenoid emulsions suitable for parenteral administration

A stable oil-in-water emulsion suitable for parenteral administration, containing less than 10% by weight lecithin, consisting of an aqueous phase and of an oil phase which is very finely dispersed by means of a physiologically tolerated emulsifier and which contains at least one carotenoid and is based on a physiologically tolerated oil or fat and comprises as emulsifier polyoxyethylene/polyoxypropylene block polymers and/or lecithin, and wherein the carotenoid is present in the oil phase in a concentration above the saturation solubility of the carotenoid in the oil or fat at room temperature.

Magnet cuff for vascular catheters and bloodlines

A catheter (100) having a catheter body (102) having a proximal end (106) and a distal end (104) and a proximal portion fixedly connected to the proximal end. A magnet (120,220,320) is disposed around the catheter body (112) distally of the proximal portion and may be contained within a hub (208, 308).

Cooling system for wound electrolytic capacitor

ABSTRACT OF THE DISCLOSURE A cooling system for an electrical wound electrolyte capacitor wherein the capacitor winding 4 is mounted in a metallic cylindrical-shape housing 5 and the winding 4 has electric foils 7 and 9 which project from both ends with one of the foils being in thermic contact with the floor of the housing 6 and the other foil 9 being in thermal contact with a metallic plate 16. The heat bridges thus formed by faster and greater heat removal for high alternating currents because the temperature within the capacitor is reduced by the two separate bridges.

Finely dispersed carotenoid and retinoid suspensions and their preparation

Finely dispersed carotenoid or retinoid suspensions are prepared by dissolving the carotenoid or retinoid is a volatile, water-miscible organic solvent at 50°C-250°C, where appropriate under elevated pressure, within less than 10 sec and immediately thereafter mixing the solution with an aqueous medium at from 0 to 90°C, wherein the mixing with the aqueous medium takes place in the absence of a protective colloid and in the presence of at least one physiologically tolerated emulsifier.

Smart resolution valve pressure control

The Smart Resolution Valve Pressure Control System allows any pressure control system using valve state pulsing to modify airflow at an optimum and consistent range of operation thereby enhancing control accuracy and increasing the useable cycle life of any valve combination used.

Cutting balloon catheter assembly

A cutting balloon catheter assembly (100) including a dual lumen catheter (130) having a distal end (134), an inflation/deflation lumen (138) and a second or guidewire lumen (136). The assembly further includes an inflatable balloon (110) having an interior cavity (116) and an expandable covering (120) disposed about the balloon wherein the covering has an array of cutting edges. In the assembly, the balloon (110) is fixedly connected to the distal end (134) of the catheter and the interior cavity (116) of the balloon (110) is in fluid communication with the first lumen (138) of the catheter (130). A method of removing obstructions (149) from vessel walls (154) using the present invention is also disclosed wherein the cutting edges abrade the stenoses, plaque or lesions along the vessel walls, when the catheter assembly is reciprocally moved longitudinally or rotationally after inflation of the balloon.

17alpha-fluoro-17beta-hydroximinomethyl steroids, a method for production thereof and pharmaceutical compositions comprising said compounds

Valve control system

System for facilitating intranasal guidance

A sphenocath (300) including a sheath assembly (340) including a sheath hub with a sheath tube extending therefrom with a passage extending from a proximal end of the sheath hub to a distal end of the sheath tube; a catheter assembly (310) including a catheter hub with a catheter tube extending therefrom with a passage extending from a proximal end of the catheter hub to a distal end of the catheter tube; wherein the catheter assembly passes through the sheath assembly with a portion of the catheter hub engaging a portion of the sheath hub to limit relative rotation between the hubs while permitting relative axial movement such that in an initial non-extended position the distal end of the catheter tube is proximate to the distal end of the sheath tube. A system further including a guidewire is also provided.

Method of implanting a multi-lumen catheter

A catheter tunneling device ( 100 ) including a tunneler ( 110 ) including a proximal tip ( 112 ), a distal end ( 114 ), and an elongated body ( 118 ) extending between the proximal tip and the distal end. The device further includes an adapter ( 120 ) including a generally elongated body ( 122 ) having a distal end ( 126 ) and a proximal end ( 124 ) and a longitudinal axis ( 128 ) extending therethrough between the distal end and the proximal end. The proximal end ( 124 ) of the adapter ( 120 ) is connected to the distal end ( 114 ) of the tunneler ( 110 ). The distal end ( 126 ) of the adapter ( 120 ) comprises a connector for connecting a plurality of catheter lumens ( 200,202 ) thereto. A method of subcutaneously tunneling a catheter under a patient's skin using the tunneling device is also disclosed.

Huber needle with safety tube

A Huber needle assembly includes a needle, a safety tube substantially around at least a portion of the needle, and a skin plate at one end of the safety tube. The safety tube is adapted to irretractably extend over the needle.

Compositions for enteral application of microorganisms

The present invention describes a process for the manufacture of a solid composition comprising a microorganism, which process comprises a first step of blending and/or compacting the microorganism with a salt of a medium or long-chain fatty acid to prepare a powderous mixture or compacted granulate, and a second step of providing said powderous mixture or compacted granulate with a coating. The microorganisms are preferably probiotics. The invention also relates to the solid composition obtained by said process and to its use in food.

PNEUMATIC SHOCK ABSORBER

Fluid channel, power semiconductor module and method for fabricating a power semiconductor module

A fluid channel for a power semiconductor module includes a die carrier configured to carry a plurality of semiconductor dies on a first side, a plurality of cooling elements arranged on a second side of the die carrier opposite the first side, and a channel wall arranged opposite the second side of the die carrier and forming a cavity. The cooling elements are arranged in the cavity. The cooling elements are attached to the die carrier at attachment points. A majority of the attachment points are positioned vertically in alignment with positions of the semiconductor dies.

Tube filling machine with a tube body transfer device and method for transferring tube bodies

Eine Tubenfüllmaschine besitzt einen Tubenkörper-Übergabevorrichtung, die einen Schacht mit zumindest einer Seitenwand und einem Schachtboden aufweist. In dem Schacht sind eine Vielzahl von Tubenkörpern unter Bildung eines auf dem Schachtboden aufliegenden Tubenkörperstapels in horizontaler Ausrichtung parallel nebeneinander und übereinanderliegend aufnehmbar. Im unteren Bereich des Schachtes ist eine Transportvorrichtung angeordnet, mittels der die Tubenkörper durch eine Auslassöffnung der Seitenwand aus dem Schacht heraustransportierbar sind. Die Transportvorrichtung und die Auslassöffnung sind derart ausgebildet, dass mittels der Transportvorrichtung mehrere Tubenkörper einer unteren Lage des Tubenkörperstapels gleichzeitig an eine Fördervorrichtung übergebbar sind, die neben dem Schacht angeordnet ist.

Locking guidewire straightener

A guidewire straightener assembly ( 50,200,300,400 ) including a guidewire tube ( 56,250,450 ) with a tubular passage therethrough having a first diameter and a distal end, optionally including a collar ( 58,260,462 ) having a second diameter larger than the first diameter. The assembly also includes a guidewire straightener ( 10,210,410 ) having a distal end ( 12,212,412 ), a proximal end ( 14,214,414 ) having an exterior surface with a diameter sized to fit within the guidewire tube, and a longitudinal passageway ( 18,218,418 ) therethrough sized to accept the guidewire ( 52,202,402 ). The proximal end of the guidewire straightener further includes a biasing member ( 20,220,420 ) with at least one finger ( 26,216,416 ) therealong. The assembly further includes a guidewire ( 52,202,402 ) disposed within the tubular passage and the longitudinal passageway( 18,218,418 ). When the guidewire straightener ( 10,210,410 ) is disposed within the guidewire tube in a first position with its biasing member in the tubular passage, the at least one finger ( 26,216,416 ) is biased by the tubular passage into frictional engagement with the guidewire; when disposed in a second position, the at least one finger is disposed away from frictional engagement with the guidewire.

Huber needle with safety tube

A Huber needle assembly includes a needle, a safety tube substantially around at least a portion of the needle, and a skin plate at one end of the safety tube. The safety tube is adapted to irretractably extend over the needle.

Induction tract for internal combustion engine

The induction tract (1) has two separate pipes discharging into an inlet passage (16) in the cylinder head, approaching the inlet valve (19). The first inlet pipe (3) is elongated, with a straight middle portion (9) with a large number of perforations (14) which may be covered by a sliding sleeve (11). The sleeve may cover the end of the short second pipe when the perforations are covered. The inlet ends of the pipes are bellmouthed. Movement of the sleeve changes the effective length of the induction tract.

Cold water-dispersible compositions of fat-soluble active substances

Partially decomposed soy protein is used as protecting colloid for fat-soluble active substances.

Luer with integrated clamp

Provided here is a tubing connector having a body that has a first end, having a first opening and a second end having a second opening. A passageway extends through the body between the first opening and the second opening. A side opening including a first side wall, and opposing second side wall and a latch catch disposed between the first and second side walls extends from the passageway through the body. The body also has a cannula extending into the passageway from the first end toward the second end. The side opening is disposed between the cannula and the second end. The connector also has a clamping member, having a first clamping end that is hingedly connected to the body and a second clamping end that is adapted to releasably engage the latch catch. A clamp portion is disposed between the first clamping end and the second clamping end.

Phytase in ready-to-drink soft drinks

The present invention relates to an acidic ready to drink beverage having a water activity greater than 0.95, a pH value lower than 6, and enriched with an active phytase enzyme.

Process for the preparation of 6-methyl-3,4-dihydro-1, 2,3-oxathiazin-4-one 2,2-dioxide and for the purification thereof

Abstract of the disclosure: Process for ?he preparation of the non-toxic salts of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-dioxide The non-toxic salts of 6-methyl-3,4-dihydro-1,2,3-oxa-thiazin-4-one 2,2-dioxide are prepared by cyclizing aceto-acetamide-N-sulfonic acid or its salts with an at least approximately equimolar amount of SO3 in the presence of a water-immiscible, inert organic solvent and, if appropriate, also an inert inorganic solvent, hydrolyzing the 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-di-oxide obtained in the form of the SO3-adduct after the cyclization reaction, in the event that the amount of SO3 employed is more than equimolar, purifying the organic phase (which has separated out) by extraction with a small volume of water or dilute aqueous sulfuric acid, prefer-ably only with water, and isolating, by neutralization with bases, the non-toxic salts of the 6-methyl-3,4-di-hydro-1,2,3-oxathiazin-4-one 2,2-diox;de from the organic phase thus purified. The said salts are obtained in this process in an extremely pure form; they are valuable synthetic sweetening agents. The potassium salt is known as acesulfam (K).

Rice-based food compositions and processes for their preparation.

Catheter tunneler and adapter

A catheter tunneling device is disclosed. The device includes a proximal portion including a proximal tip, a distal end, and an elongated body extending between the proximal tip and the distal end. The device further includes a distal portion including a generally elongated body having a distal end and a proximal end and a longitudinal axis extending therethrough between the distal end and the proximal end. The proximal end of the distal portion is connected to the distal end of the proximal portion. The distal end of the distal portion comprises a connection means for connecting a plurality of catheter lumens thereto. A method of subcutaneously tunneling a catheter under a patient's skin using the tunneling device is also disclosed.

Science, technology, engineering and mathematics based cyber security education system

According to one aspect, a science, technology, engineering and mathematics (STEM) based cyber security education system is provided. A training component, a knowledge component, and a collaborative component are interfaced to a distance learning component to form a STEM-based cyber security education system interface on an educational content server. The educational content server is coupled to a content database configured to access STEM-based cyber security educational content associated with one or more of: the training component, the knowledge component, and the collaborative component. Asynchronous delivery of the STEM-based cyber security educational content is provided to an end user computer in response to a user request. An interactive session is established between one or more experts and the end user computer to provide synchronous delivery of STEM-based cyber security materials.

Fluid flow control in bakeries - uses level sensor in supply tanks to maintain constant level and control outflow through base valve

Plant extract and pufa combinations

The present invention relates to the combination of a plant extract, such as oregano extract and a polyunsaturated fatty acid or a derivative (such as an ethyl ester “PUFA EE”) which is stable under strorage conditions.

PROCESS FOR OBTAINING NON-TOXIC SALTS FROM 6-METHYL-3,4-DIHYDRO-1,2,3-OXATIAZIN-4-ONA 2,2-DIOXIDE

HUBER SAFETY NEEDLE

Un montaje de aguja de seguridad Huber incluye un cuerpo configurado para recibir una aguja. El cuerpo incluye además una porción superior que tiene una primera porción de fijación acoplada con la misma, una porción inferior que tiene una segunda porción de fijación acoplada con la misma y un mecanismo de articulación. La aguja tiene una punta de aguja configurada para ser recibida en el cuerpo. El mecanismo de articulación es configurado para la transición, en forma operativa del cuerpo entre una configuración cerrada y una configuración abierta. La configuración cerrada permite que al menos una porción de la aguja, que incluye la punta de aguja, se extienda por debajo de la superficie inferior de la porción inferior del cuerpo. La configuración abierta permite que la punta de aguja sea recibida, en forma segura, dentro de la porción inferior, de manera que no se extienda por debajo de la superficie inferior de la porción inferior.