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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 40. Отображено 40.
27-12-2007 дата публикации

Method and apparatus for an air bearing surface to reduce contamination due to saturation water vapor pressure in a hard disk drive

Номер: US20070297092A1
Автор: Shuyu Zhang, Brian D. Strom, SungChang Lee, George Tyndall
Принадлежит: SAMSUNG ELECTRONICS CO., LTD.

A slider operating air bearing surface (ABS) to remove a front saturation water vapor pressure peak near a front bulwark and a bad flow pattern area the between front bulwark and a central island. The ABS implementing these operations. Alternatively, ABS includes a front bulwark channel in the front bulwark and a central fin between the front bulwark and the central island. Slider includes an embodiment of the ABS. Head gimbal assembly (HGA) includes the slider. Head stack assembly includes at least one HGA. Hard disk drive includes the head stack assembly. Manufacturing methods for the slider, the HGA, the head stack assembly, the hard disk drive, and these items as products of their manufacturing processes.

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Номер записи: 1
27-03-2008 дата публикации

Advanced air bearing and detection method for media glide testing at ultra-low flying height

Номер: US20080074116A1
Автор: Dougman Kim, Shuyu Zhang
Принадлежит: Samsung Electronics Co., Ltd.

A glide head assembly that can be used to certify disks of hard disk drives. The assembly includes a glide head that is coupled to a suspension arm. The assembly further has a contact sensor coupled to the head. The contact sensor includes a center plate and four beams. The beams are coupled to corresponding sensor elements. Contact between the head and the disk will cause the beams to deflect. The deflection of the beams is sensed by the sensor elements and processed to detect head/disk contact. The number, orientation and amplitude of the beams that are deflected can be processed to determine the pitch and roll angles of the glide head.

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Номер записи: 2
20-07-2010 дата публикации

Method and apparatus for an air bearing surface to reduce contamination due to saturation water vapor pressure in a hard disk drive

Номер: US0007760469B2
Автор: Shuyu Zhang, Brian D. Strom, SungChang Lee, George Tyndall, ZHANG SHUYU, STROM BRIAN D, LEE SUNGCHANG, TYNDALL GEORGE, STROM BRIAN D.
Принадлежит: Samsung Electronics Co., Ltd., SAMSUNG ELECTRONICS CO LTD, SAMSUNG ELECTRONICS CO., LTD.

A slider operating air bearing surface (ABS) to remove a front saturation water vapor pressure peak near a front bulwark and a bad flow pattern area the between front bulwark and a central island. The ABS implementing these operations. Alternatively, ABS includes a front bulwark channel in the front bulwark and a central fin between the front bulwark and the central island. Slider includes an embodiment of the ABS. Head gimbal assembly (HGA) includes the slider. Head stack assembly includes at least one HGA. Hard disk drive includes the head stack assembly. Manufacturing methods for the slider, the HGA, the head stack assembly, the hard disk drive, and these items as products of their manufacturing processes.

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Номер записи: 3
06-08-2009 дата публикации

Method and apparatus for an air bearing surface in a hard disk drive using at least one patterned disk surface

Номер: US20090195932A1
Автор: Shuyu Zhang
Принадлежит: SAMSUNG ELECTRONICS CO., LTD.

Estimating methods and apparatus are disclosed for the patterned flying height of an air bearing surface over a patterned surface from the flying height over a smooth surface minus a flying height delta based upon the patterned surface. A hard disk drive is disclosed including the air bearing surface over a rotating disk surface that at least partly includes a patterned surface. A slider with the air bearing surface is disclosed for use over the patterned disk surface. Also disclosed: a head gimbal assembly including the slider and a head stack assembly coupling through the head gimbal assembly to position the slider.

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Номер записи: 4
25-03-2008 дата публикации

Method and apparatus for improved starting and/or stopping in a contact start-stop (CSS) hard disk drive.

Номер: US0007349169B2
Автор: SungChang Lee, Brian D. Strom, Shuyu Zhang, George Tyndall, LEE SUNGCHANG, STROM BRIAN D, ZHANG SHUYU, TYNDALL GEORGE, STROM BRIAN D.
Принадлежит: Samsung Electronics Co., Ltd., SAMSUNG ELECTRONICS CO LTD, SAMSUNG ELECTRONICS CO., LTD.

CSS hard disk drive providing improved take-off and/or touchdown by asserting pitch actuation control signal stimulating a pitch actuator to flex a flexure finger, altering the pitch angle of slider coupling through flexure finger to pitch actuator. Method implemented by embedded circuit and/or embedded processor. Manufacturing embedded processor, embedded circuit, CSS hard disk drive, and these process products.

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Номер записи: 5
02-09-2008 дата публикации

Method and apparatus reducing flying height drop in a hard disk drive under humid conditions

Номер: US0007420760B2
Автор: Shuyu Zhang, Brian D. Strom, SungChang Lee, ZHANG SHUYU, STROM BRIAN D, LEE SUNGCHANG, STROM BRIAN D.
Принадлежит: Samsung Electronics Co., Ltd., SAMSUNG ELECTRONICS CO LTD, SAMSUNG ELECTRONICS CO., LTD.

A slider with an intake heater near front edge heating air passing between air bearing surface and rotating disk surface to reduce change in flying height caused by water condensation. Method of operating the slider. Head gimbals assembly including slider. Head stack assembly including at least one HGA. Operating hard disk drive by receiving temperature and humidity reading to determine heater control and asserting heater control to stimulate intake heater to heat air. Embedded processor directing hard disk drive at least partly implementing operations. Embedded circuit including embedded processor. A hard disk drive including temperature, humidity sensors, embedded circuit and head stack assembly. Manufacturing methods for slider, head gimbals assembly, head stack assembly, embedded processor, embedded circuit and hard disk drive, and these items as products of their manufacturing processes.

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Номер записи: 6
27-03-2012 дата публикации

Air bearing surface method and apparatus optimizing flying height on demand efficiency during flying height on demand activity of slider in a hard disk drive

Номер: US0008144422B2
Автор: Shuyu Zhang, ZHANG SHUYU
Принадлежит: ZHANG SHUYU

A slider including air bearing surface with Flying height On-Demand (FOD) protrusion with method of controlling airflow to maximize FOD efficiency as ratio of change in vertical position to protrusion height. Slider including components controlling the air flow to maximize FOD efficiency and/or including specific components minimizing an air bearing pressure under a Flying height On Demand (FOD) operation away from a maximum air bearing pressure, placing a peak pressure off of an FOD area create by a FOD protrusion, and shrinking a high peak pressure area of the air bearing surface. Hard disk drive includes head stack assembly, which includes head gimbal assembly, which includes the slider. Manufacturing method for slider, head gimbal assembly, head stack assembly and hard disk drive, and these items as products of these processes.

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Номер записи: 7
21-05-2009 дата публикации

Self PSA adjustment using thermal adapter on suspension for improving takeoff in hot/wet environment

Номер: US20090128959A1
Автор: Shuyu Zhang, Zhong-Qing Gong
Принадлежит: Samsung Electronics Co., Ltd.

A suspension arm assembly for a hard disk drive that includes a suspension arm and a thermal adaptor. The thermal adaptor has a thermal coefficient of expansion that is different from the thermal coefficient of expansion of the suspension arm so that a pitch static angle is increased with an increase in temperature. The suspension arm assembly is attached to an actuator arm and coupled to a head of the disk drive. The head may be parked on a landing zone of a disk surface while the disk is stationary. When the disk is spun, an air bearing is formed between the disk surface and the head. If the drive is operating at an elevated temperature the static angle of the suspension arm will increase to increase the slider's pitch angle and air bearing flying height.

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Номер записи: 8
19-07-2007 дата публикации

Method and apparatus regulating saturation water vapor pressure in a hard disk drive

Номер: US20070165322A1
Автор: Brian D. Strom, Shuyu Zhang, SungChang Lee, George Tyndall
Принадлежит: SAMSUNG ELECTRONICS CO., LTD.

Method operating hard disk drive (HDD) by receiving temperature and pressure readings from sensors, determining condensation danger from reading and asserting heat-up control to stimulate a thermoelectric device to move heat from exterior to interior thermal zone of HDD. Apparatus implementing method including embedded circuit, embedded processor in embedded circuit, thermal controller, thermal processor in thermal controller, and HDD. Manufacturing methods for apparatus and apparatus as products of these processes.

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Номер записи: 9
05-01-2010 дата публикации

Slider having fast take-off fluid bearing surface

Номер: US0007643251B1
Автор: Shuyu Zhang, Francis Crimi, ZHANG SHUYU, CRIMI FRANCIS
Принадлежит: Seagate Technology LLC, SEAGATE TECHNOLOGY LLC

A disk drive for storing data includes a rotating storage disk and a slider positioned near the storage disk. The slider has a flying side and a read/write head. The flying side includes a leading bearing surface and a leading recessed surface positioned near a leading edge of the slider. The leading bearing surface can include a leading transverse section that is positioned within approximately 20 and 200 microns of the leading edge. The leading recessed surface is positioned between the leading transverse section and the leading edge. The leading bearing surface and the leading recessed surface cooperate to form a relatively high pressure area near the leading edge that facilitates a relatively rapid take-off of the slider away from the storage disk during start up of the disk drive.

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Номер записи: 10
12-10-2021 дата публикации

Soft neural electrode based on three-dimensional porous graphene foam material and use of three-dimensional porous graphene foam material to prepare bone defect filler

Номер: US0011145850B2
Автор: Judong Luo, Qi Zhang, Yuyou Qiu, Shuyu Zhang, Qin Song, Guangyu Tang, Jianping Cao, Hua Jiang, LUO JUDONG, ZHANG QI, QIU YUYOU, ZHANG SHUYU, SONG QIN, TANG GUANGYU, CAO JIANPING, JIANG HUA, Luo, Judong, Zhang, Qi, Qiu, Yuyou, Zhang, Shuyu, Song, Qin, Tang, Guangyu, Cao, Jianping, Jiang, Hua
Принадлежит: SOOCHOW UNIVERSITY, UNIV SOOCHOW

The invention provides a neural electrode, including a current generation device, a first and a second electrode. The current generation device is connected to the first and second electrodes through a conductive metal wire respectively. At least one of the first and second electrodes is a graphene electrode. The graphene electrode has soft texture and desirable stability to tolerate the repeated pressing and folding treatment, very high charge injection efficiency, and desirable in vivo stability, and is configured to electrically stimulate tissues and organs such as hearts and nerves to promote electrical stimulation and repair of neurons, to further promote regeneration of neural functions. The invention further provides use of a mineralized three-dimensional porous graphene foam material to prepare a bone defect filler. The bone defect filler has desirable biological compatibility, promotes cell proliferation, and accelerates and induces osteogenic differentiation of bone marrow mesenchymal stem cells.

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Номер записи: 11
04-04-2023 дата публикации

Variable dual-directional thermal compensator for arrayed waveguide grating (AWG) modules

Номер: US0011619780B2
Автор: Shuyu Zhang, Glenn Lee, Mike Chia Huang, Taizhong Huang
Принадлежит: Molex, LLC

A thermal compensator, for use in connection with arrayed waveguide grating (AWG) modules which are, in turn, utilized in conjunction with wavelength multiplexing and de-multiplexing within optical networks, is disclosed. The thermal compensator comprises a bow-shaped frame member, a central bar member, and a screw. The bow-shaped frame member is characterized by a higher or great coefficient of thermal expansion (CTE) than that of the central bar member such that the bow-shaped frame member can expand and elongate at a greater rate than can the central bar member under hot temperature conditions, however, under cold temperature conditions, the rate of contraction of the bow-shaped member is effectively retarded by the slower rate of contraction of the central bar member. The bow-shaped frame member is adapted to be attached to a movable section of an athermal arrayed waveguide grating (AAWG) module such that the expansion and contraction movements of the bow-shaped member influence the ...

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Номер записи: 12
18-05-2010 дата публикации

Method and apparatus intelligently adapting to environmental conditions inside and outside a hard disk drive

Номер: US0007719792B2
Автор: Brian D. Strom, SungChang Lee, Shuyu Zhang, STROM BRIAN D, LEE SUNGCHANG, ZHANG SHUYU, STROM BRIAN D.
Принадлежит: Samsung Electronics Co., Ltd., SAMSUNG ELECTRONICS CO LTD, SAMSUNG ELECTRONICS CO., LTD.

Hard disk drive (HDD) including humidity sensor measuring interior and second humidity sensor measuring exterior with door actuator controlling door for mass transfer between interior and exterior based upon determination of whether or not to transfer. HDD may further include and use temperature sensors for interior and/or exterior to further control door. An embedded circuit and processor at least partly implementing these operations. External cover including door and door actuator, possibly second sensors. Manufacturing methods and these items as their products.

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Номер записи: 13
08-12-2020 дата публикации

Transdermal peptide with nuclear localization ability and use thereof

Номер: US0010858408B2
Автор: Shuyu Zhang, Jianping Cao, Daojiang Yu, Wei Zhu, ZHANG SHUYU, CAO JIANPING, YU DAOJIANG, ZHU WEI, Zhang, Shuyu, Cao, Jianping, Yu, Daojiang, Zhu, Wei
Принадлежит: SOOCHOW UNIVERSITY, UNIV SOOCHOW

A transdermal peptide with a nuclear localization ability and having an amino acid sequence as shown in SEQ ID NO: 1 is disclosed. A fusion protein including a macromolecular protein with one end being linked to the transdermal peptide is also disclosed. The transdermal peptide can be used in the preparation of a medicament or a transdermal preparation for treating skin diseases. A medicament for treating a skin disease includes the transdermal peptide and a pharmaceutically acceptable excipient. The transdermal peptide enters the cells autonomously to locate in the nuclei, and can penetrate through the stratum corneum of the skin into cells in the dermis. The peptide is conveniently synthesized artificially and suitable for transdermal administration, and has a therapeutic potential via transdermal administration by carrying a drug for treating skin diseases.

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Номер записи: 14
20-10-2015 дата публикации

Air bearing area configuration for reducing flying height hump across a stroke

Номер: US0009165579B1
Автор: Shuyu Zhang, ZHANG SHUYU
Принадлежит: Western Digital (Fremont), LLC, WESTERN DIGITAL FREMONT LLC, WESTERN DIGITAL (FREMONT), LLC

A disk drive is provided having a dynamic flying height or touch down power profile that is substantially flat across its stroke along the radius of a recording medium. At least two air-channeling elements are provided in a slider of the disk drive, that with the read/write head, flies above a surface of the recording medium. At an inner diameter and an outer diameter of the recording medium, the at least two air-channeling elements direct incoming air flow to an air bearing space defined by a bottom surface of the slider and the surface of the recording medium, increasing the flying height of the slider/read/write head at the inner diameter and outer diameter of the recording medium, thereby negating the effect of a middle diameter flying height hump of the recording medium.

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Номер записи: 15
06-09-2007 дата публикации

Air bearing surface of a hard disk drive head

Номер: US20070206326A1
Автор: Shuyu Zhang
Принадлежит: Samsung Electronics Co., Ltd.

A head for a hard disk drive. The head includes an air bearing surface that has a central pad. The central pad contains the read/write transducers of the head. The air bearing surface has a particle obstruction pad adjacent to the central pad. The obstruction pad creates a mechanical barrier that prevents particles from flowing onto the central pad.

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Номер записи: 16
17-11-2015 дата публикации

Air bearing area configuration for contaminating particle removal

Номер: US0009190089B1
Автор: Shuyu Zhang, ZHANG SHUYU
Принадлежит: Western Digital (Fremont), LLC, WESTERN DIGITAL FREMONT LLC, WESTERN DIGITAL (FREMONT), LLC

A disk drive for redirecting contaminating particulate matter away from an area bearing of a slider element. At least two etched channels are provided in the slider element of the disk drive. The at least two etched channels direct incoming air flow to a leading edge of the slider element from the leading edge towards respective sides of the slider element. Particulate matter that may be progressing towards the air bearing are redirected by virtue of the incoming air flow to the leading edge and expelled from the air bearing via the at least two etched channels.

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Номер записи: 17
27-12-2007 дата публикации

Method and apparatus for improved starting and/or stopping in a contact start-stop (CSS) hard disk drive

Номер: US20070297084A1
Автор: SungChang Lee, Brian D. Strom, Shuyu Zhang, George Tyndall
Принадлежит: SAMSUNG ELECTRONICS CO., LTD.

CSS hard disk drive providing improved take-off and/or touchdown by asserting pitch actuation control signal stimulating a pitch actuator to flex a flexure finger, altering the pitch angle of slider coupling through flexure finger to pitch actuator. Method implemented by embedded circuit and/or embedded processor. Manufacturing embedded processor, embedded circuit, CSS hard disk drive, and these process products.

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Номер записи: 18
01-03-2022 дата публикации

Transdermal peptide with nuclear localization ability and use thereof

Номер: US0011261222B2
Автор: Shuyu Zhang, Jianping Cao, Daojiang Yu, Wei Zhu
Принадлежит: SOOCHOW UNIVERSITY

A transdermal peptide with a nuclear localization ability and having an amino acid sequence as shown in SEQ ID NO: 1 is disclosed. A fusion protein including a macromolecular protein with one end being linked to the transdermal peptide is also disclosed. The transdermal peptide can be used in the preparation of a medicament or a transdermal preparation for treating skin diseases. A medicament for treating a skin disease includes the transdermal peptide and a pharmaceutically acceptable excipient. The transdermal peptide enters the cells autonomously to locate in the nuclei, and can penetrate through the stratum corneum of the skin into cells in the dermis. The peptide is conveniently synthesized artificially and suitable for transdermal administration, and has a therapeutic potential via transdermal administration by carrying a drug for treating skin diseases.

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Номер записи: 19
27-12-2007 дата публикации

Method and apparatus reducing flying height drop in a hard disk drive under humid conditions

Номер: US20070297085A1
Автор: Shuyu Zhang, Brian D. Strom, SungChang Lee
Принадлежит: SAMSUNG ELECTRONICS CO., LTD.

A slider with an intake heater near front edge heating air passing between air bearing surface and rotating disk surface to reduce change in flying height caused by water condensation. Method of operating the slider. Head gimbal assembly including slider. Head stack assembly including at least one HGA. Operating hard disk drive by receiving temperature and humidity reading to determine heater control and asserting heater control to stimulate intake heater to heat air. Embedded processor directing hard disk drive at least partly implementing operations. Embedded circuit including embedded processor. A hard disk drive including temperature, humidity sensors, embedded circuit and head stack assembly. Manufacturing methods for slider, head gimbal assembly, head stack assembly, embedded processor, embedded circuit and hard disk drive, and these items as products of their manufacturing processes.

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Номер записи: 20
27-06-2006 дата публикации

Composite head arm assembly with thermal control of gram load

Номер: US0007068470B1
Автор: Jafar Hadian, Tadashi Yogi, Shuyu Zhang, HADIAN JAFAR, YOGI TADASHI, ZHANG SHUYU
Принадлежит: Maxtor Corporation, MAXTOR CORP, MAXTOR CORPORATION

A disk drive includes a drive housing, a storage disk coupled to the drive housing and a head arm assembly coupled to the drive housing. The head arm assembly includes an adjuster and a slider coupled to the adjuster. As provided herein, the adjuster changes the gram load that is applied to the slider as the temperature near the adjuster changes. In one of the embodiments, the adjuster increases the gram load that is applied to the slider as the temperature near the adjuster decreases.

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Номер записи: 21
31-07-2008 дата публикации

Method and apparatus intelligently adapting to environmental conditions inside and outside a hard disk drive

Номер: US20080180835A1
Автор: Brian D. Strom, SungChang Lee, Shuyu Zhang
Принадлежит: SAMSUNG ELECTRONICS CO., LTD.

Hard disk drive (HDD) including humidity sensor measuring interior and second humidity sensor measuring exterior with door actuator controlling door for mass transfer between interior and exterior based upon determination of whether or not to transfer. HDD may further include and use temperature sensors for interior and/or exterior to further control door. An embedded circuit and processor at least partly implementing these operations. External cover including door and door actuator, possibly second sensors. Manufacturing methods and these items as their products.

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Номер записи: 22
22-05-2008 дата публикации

Air Bearing Surface Method and Apparatus Optimizing Flying Height On Demand Efficiency During Flying Height on Demand Activity of Slider in a Hard Disk Drive

Номер: US20080117550A1
Автор: Shuyu Zhang
Принадлежит: SAMSUNG ELECTRONICS CO LTD

A slider including air bearing surface with Flying height On-Demand (FOD) protrusion with method of controlling airflow to maximize FOD efficiency as ratio of change in vertical position to protrusion height. Slider including means for controlling the air flow to maximize FOD efficiency and/or including specific means for minimizing an air bearing pressure under a Flying height On Demand (FOD) operation away from a maximum air bearing pressure, means for placing a peak pressure off of an FOD area create by a FOD protrusion, and means for shrinking a high peak pressure area of the air bearing surface. Hard disk drive includes head stack assembly, which includes head gimbal assembly, which includes the slider. Manufacturing method for slider, head gimbal assembly, head stack assembly and hard disk drive, and these items as products of these processes.

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Номер записи: 23
03-05-2011 дата публикации

Controlled fly height slider with necked ABS

Номер: US0007936538B1
Автор: Shuyu Zhang, Francis Crimi, ZHANG SHUYU, CRIMI FRANCIS
Принадлежит: Seagate Technology LLC, SEAGATE TECHNOLOGY LLC

A slider that includes a necked ABS pad is disclosed. More specifically, the slider includes an ABS pad having a first ABS region and a second ABS region, where the second ABS region is disposed immediately in front of the first ABS region proceeding in the direction of a leading edge of the slider. A transducer and a thermal actuator each may be disposed within the first ABS region. The width of the second ABS region (a necked portion of the ABS pad) is less than a width of the first ABS region.

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Номер записи: 24
17-11-2015 дата публикации

Multi step lube blocking air bearing area configuration

Номер: US0009190090B1
Автор: Shuyu Zhang, Lanshi Zheng, ZHANG SHUYU, ZHENG LANSHI
Принадлежит: Western Digital (Fremont), LLC, WESTERN DIGITAL FREMONT LLC, WESTERN DIGITAL (FREMONT), LLC

A disk drive is provided having one or more structural air bearing surface (ABS) features that can block particulate matter, such as lube droplets that may enter the air bearing from the trailing edge or rearward portion of the slider. Moreover, such structural ABS features can influence air flow within or about the air bearing to prevent or at least reduce the accumulation of particles and/or droplets in one or more areas of the air bearing to reduce the reliability problems induced by particle contamination and lube pick-up.

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Номер записи: 25
02-01-2020 дата публикации

TRANSDERMAL PEPTIDE WITH NUCLEAR LOCALIZATION ABILITY AND USE THEREOF

Номер: US20200002389A1
Автор: CAO Jianping, YU Daojiang, ZHANG Shuyu, Zhu Wei
Принадлежит:

The invention relates to a transdermal peptide with a nuclear localization ability and having an amino acid sequence as shown in SEQ ID NO: 1. The invention provides a fusion protein with a nuclear localization ability, which comprises a macromolecular protein with one end being linked to the transdermal peptide. The invention also discloses the use of the transdermal peptide in the preparation of a medicament or a transdermal preparation for treating skin diseases. The invention further provides a medicament for treating a skin disease, comprising the transdermal peptide and a pharmaceutically acceptable excipient. The transdermal peptide enters the cells autonomously to locate in the nuclei, and can penetrate through the stratum corneum of the skin into cells in the dermis. The peptide is conveniently synthesized artificially and suitable for transdermal administration, and has a therapeutic potential via transdermal administration by carrying a drug for treating skin diseases. 1. A transdermal peptide with a nuclear localization ability , having an amino acid sequence as shown in SEQ ID NO: 1 , wherein the transdermal peptide enters the eukaryotic cells autonomously.2. The transdermal peptide according to claim 1 , wherein the transdermal peptide is further linked to fluorescein.3. The transdermal peptide according to claim 2 , wherein the fluorescein is fluorescein isothiocyanate claim 2 , rhodamine or carboxyfluorescein (FAM).4. The transdermal peptide according to claim 1 , wherein the eukaryotic cells are HaCaT cells claim 1 , WS1 cells claim 1 , TE-1 cells claim 1 , Eca-109 cells claim 1 , or HeLa cells.5. A fusion protein with a nuclear localization ability claim 1 , comprising a macromolecular protein claim 1 , one end of which is linked to the transdermal peptide according to .6. The fusion protein with a nuclear localization ability according to claim 5 , wherein the other end of the macromolecular protein is linked to a fluorescent protein.7. The fusion ...

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Номер записи: 26
25-02-2021 дата публикации

TRANSDERMAL PEPTIDE WITH NUCLEAR LOCALIZATION ABILITY AND USE THEREOF

Номер: US20210054035A1
Автор: CAO Jianping, YU Daojiang, ZHANG Shuyu, Zhu Wei
Принадлежит:

A transdermal peptide with a nuclear localization ability and having an amino acid sequence as shown in SEQ ID NO: 1 is disclosed. A fusion protein including a macromolecular protein with one end being linked to the transdermal peptide is also disclosed. The transdermal peptide can be used in the preparation of a medicament or a transdermal preparation for treating skin diseases. A medicament for treating a skin disease includes the transdermal peptide and a pharmaceutically acceptable excipient. The transdermal peptide enters the cells autonomously to locate in the nuclei, and can penetrate through the stratum corneum of the skin into cells in the dermis. The peptide is conveniently synthesized artificially and suitable for transdermal administration, and has a therapeutic potential via transdermal administration by carrying a drug for treating skin diseases. 1. (canceled)2. (canceled)3. (canceled)4. (canceled)5. A fusion protein with a nuclear localization ability , comprising a macromolecular protein , one end of which is linked to an isolated transdermal peptide with a nuclear localization ability , having an amino acid sequence as shown in SEQ ID NO: 1 and being linked to a fluorescein ,wherein the transdermal peptide enters the eukaryotic cells autonomously.6. The fusion protein with a nuclear localization ability according to claim 5 , wherein the other end of the macromolecular protein is linked to a fluorescent protein.7. The fusion protein with a nuclear localization ability according to claim 5 , wherein the macromolecular protein has a molecular weight of 10-50 KD.8. The fusion protein with a nuclear localization ability according to claim 5 , wherein the macromolecular protein has an amino acid sequence as shown in SEQ ID NO: 2 claim 5 , and the macromolecular protein is human superoxide dismutase.9. (canceled)10. (canceled) The present invention relates to the field of biological technology, and more particularly to a transdermal peptide with nuclear ...

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Номер записи: 27
05-05-2022 дата публикации

New and improved variable dual-directional thermal compensator for arrayed waveguide grating (awg) modules

Номер: US20220137291A1
Автор: Glenn Lee, Mike Chia HUANG, Shuyu Zhang, Taizhong Huang
Принадлежит: MOLEX LLC

A thermal compensator, for use in connection with arrayed waveguide grating (AWG) modules which are, in turn, utilized in conjunction with wavelength multiplexing and de-multiplexing within optical networks, is disclosed. The thermal compensator comprises a bow-shaped frame member, a central bar member, and a screw. The bow-shaped frame member is characterized by a higher or great coefficient of thermal expansion (CTE) than that of the central bar member such that the bow-shaped frame member can expand and elongate at a greater rate than can the central bar member under hot temperature conditions, however, under cold temperature conditions, the rate of contraction of the bow-shaped member is effectively retarded by the slower rate of contraction of the central bar member. The bow-shaped frame member is adapted to be attached to a movable section of an athermal arrayed waveguide grating (AAWG) module such that the expansion and contraction movements of the bow-shaped member influence the movement of a movable section of the athermal arrayed waveguide grating (AAWG) module in order to maintain the proper focus of the athermal arrayed waveguide grating (AAWG) module across disparate temperature conditions within which the athermal arrayed waveguide grating (AAWG) module is designed to operate.

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Номер записи: 28
11-06-2020 дата публикации

SOFT NEURAL ELECTRODE BASED ON THREE-DIMENSIONAL POROUS GRAPHENE FOAM MATERIAL AND USE OF THREE-DIMENSIONAL POROUS GRAPHENE FOAM MATERIAL TO PREPARE BONE DEFECT FILLER

Номер: US20200185703A1
Автор: CAO Jianping, JIANG Hua, LUO Judong, QIU Yuyou, SONG Qin, TANG Guangyu, ZHANG Qi, ZHANG Shuyu
Принадлежит:

The invention provides a neural electrode, including a current generation device, a first and a second electrode. The current generation device is connected to the first and second electrodes through a conductive metal wire respectively. At least one of the first and second electrodes is a graphene electrode. The graphene electrode has soft texture and desirable stability to tolerate the repeated pressing and folding treatment, very high charge injection efficiency, and desirable in vivo stability, and is configured to electrically stimulate tissues and organs such as hearts and nerves to promote electrical stimulation and repair of neurons, to further promote regeneration of neural functions. The invention further provides use of a mineralized three-dimensional porous graphene foam material to prepare a bone defect filler. The bone defect filler has desirable biological compatibility, promotes cell proliferation, and accelerates and induces osteogenic differentiation of bone marrow mesenchymal stem cells. 1. A neural electrode based on a three-dimensional porous graphene foam material , comprising a current generation device , a first electrode and a second electrode , the current generation device being connected to the first electrode and the second electrode through a conductive metal wire respectively , wherein at least one of the first electrode and the second electrode is a three-dimensional porous graphene electrode.2. The neural electrode based on a three-dimensional porous graphene foam material as claimed in claim 1 , wherein an insulating protective sleeve is disposed outside the conductive metal wire.3. The neural electrode based on a three-dimensional porous graphene foam material as claimed in claim 2 , wherein the protective sleeve is made of silica gel or polyurethane.4. The neural electrode based on a three-dimensional porous graphene foam material as claimed in claim 1 , wherein the conductive metal wire is a silver wire or a copper wire.5. The ...

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Номер записи: 29
03-02-2022 дата публикации

New and improved variable dual-directional thermal compensator for arrayed waveguide grating (awg) modules

Номер: WO2022024022A1
Автор: Glenn Lee, Mike C. HUANG, Senming Gong, Shuyu Zhang, Taizhong Huang
Принадлежит: Molex, LLC

A thermal compensator, for use in connection with arrayed waveguide grating (AWG) modules which are, in turn, utilized in conjunction with wavelength multiplexing and de-multiplexing within optical networks, is disclosed. The thermal compensator comprises a bow-shaped frame member and a central bar member. The bow-shaped frame member is characterized by a higher coefficient of thermal expansion than that of the central bar member such that the bow-shaped frame member can expand and contract at variable rates compared to that of the central bar member under certain temperature conditions. The bow-shaped frame member is adapted to be attached to a movable section of an athermal arrayed waveguide grating (AAWG) module such that the expansion and contraction movements of the bow-shaped member influence the movement of a movable section of the AAWG module in order to maintain the proper focus of the AAWG module across disparate temperature conditions.

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Номер записи: 30
15-04-2021 дата публикации

Ball retainer and angular contact ball bearing

Номер: AU2021100609A4
Автор: Haibo YANG, Hongbao ZHAO, Mingrui LI, Shuyu Zhang, Xingmin Liu, Zhengmin Wang
Принадлежит: Shandong Bote Bearing Co ltd

The present disclosure provides a ball retainer and an angular contact ball bearing. The ball retainer comprises a plurality of block-shaped isolation blocks, ball pockets are arranged on the end faces of two sides of each block-shaped isolation 5 block, the surface of each ball pocket is used for making contact with a bearing ball, the linear distance between any two points on any cross section of each block-shaped isolation block is smaller than the diameter of the corresponding bearing ball, and one block-shaped isolation block is arranged between every two adjacent bearing balls, so that the service lives of the bearing balls are prolonged, and the weight and the 10 starting torque of the bearing are reduced. The angular contact ball bearing comprises a bearing inner ring, bearing balls, a bearing outer ring and the ball retainer, a ball slide way is arranged between the bearing inner ring and the bearing outer ring, the ball retainer is used for separating the bearing balls and preventing the bearing balls from falling off, the number of the bearing balls is multiple, the number of the bearing 15 balls is the same as that of the block-shaped isolation blocks, each bearing ball can slide in the ball slide way, and the ball retainer does not affect the arrangement of the bearing inner ring and the bearing outer ring, so that the contact angle of the bearing can be increased. i/l FIG1 3 6 5 7 FIG2

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Номер записи: 31
03-09-2020 дата публикации

New and improved variable dual-directional thermal compensator for arrayed waveguide grating (awg) modules

Номер: WO2020176089A1
Автор: Glenn Lee, Michael Huang, Shuyu Zhang, Taizhong Huang
Принадлежит: Molex, LLC

A thermal compensator, for use in connection with arrayed waveguide grating (AWG) modules which are, in turn, utilized in conjunction with wavelength multiplexing and de-multiplexing within optical networks, is disclosed. The thermal compensator comprises a bow-shaped frame member, a central bar member, and a screw. The bow-shaped frame member is characterized by a higher or great coefficient of thermal expansion (CTE) than that of the central bar member such that the bow-shaped frame member can expand and elongate at a greater rate than can the central bar member under hot temperature conditions, however, under cold temperature conditions, the rate of contraction of the bow-shaped member is effectively retarded by the slower rate of contraction of the central bar member. The bow-shaped frame member is adapted to be attached to a movable section of an athermal arrayed waveguide grating (AAWG) module such that the expansion and contraction movements of the bow-shaped member influence the movement of a movable section of the athermal arrayed waveguide grating (AAWG) module in order to maintain the proper focus of the athermal arrayed waveguide grating (AAWG) module across disparate temperature conditions within which the athermal arrayed waveguide grating (AAWG) module is designed to operate.

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Номер записи: 32
28-09-2023 дата публикации

New and improved variable dual-directional thermal compensator for arrayed waveguide grating (awg) modules

Номер: US20230305227A1
Автор: Glenn Lee, Mike C. HUANG, Senming Gong, Shuyu Zhang, Taizhong Huang
Принадлежит: MOLEX LLC

A thermal compensator, for use in connection with arrayed waveguide grating (AWG) modules which are, in turn, utilized in conjunction with wavelength multiplexing and de-multiplexing within optical networks, is disclosed. The thermal compensator comprises a bow-shaped frame member and a central bar member. The bow-shaped frame member is characterized by a higher coefficient of thermal expansion than that of the central bar member such that the bow-shaped frame member can expand and contract at variable rates compared to that of the central bar member under certain temperature conditions. The bow-shaped frame member is adapted to be attached to a movable section of an athermal arrayed waveguide grating (AAWG) module such that the expansion and contraction movements of the bow-shaped member influence the movement of a movable section of the AAWG module in order to maintain the proper focus of the AAWG module across disparate temperature conditions.

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Номер записи: 33
05-01-2022 дата публикации

New and improved variable dual-directional thermal compensator for arrayed waveguide grating (awg) modules

Номер: EP3931610A1
Автор: Glenn Lee, Mike Huang, Shuyu Zhang, Taizhong Huang
Принадлежит: MOLEX LLC

A thermal compensator, for use in connection with arrayed waveguide grating (AWG) modules which are, in turn, utilized in conjunction with wavelength multiplexing and de-multiplexing within optical networks, is disclosed. The thermal compensator comprises a bow-shaped frame member, a central bar member, and a screw. The bow-shaped frame member is characterized by a higher or great coefficient of thermal expansion (CTE) than that of the central bar member such that the bow-shaped frame member can expand and elongate at a greater rate than can the central bar member under hot temperature conditions, however, under cold temperature conditions, the rate of contraction of the bow-shaped member is effectively retarded by the slower rate of contraction of the central bar member. The bow-shaped frame member is adapted to be attached to a movable section of an athermal arrayed waveguide grating (AAWG) module such that the expansion and contraction movements of the bow-shaped member influence the movement of a movable section of the athermal arrayed waveguide grating (AAWG) module in order to maintain the proper focus of the athermal arrayed waveguide grating (AAWG) module across disparate temperature conditions within which the athermal arrayed waveguide grating (AAWG) module is designed to operate.

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Номер записи: 34
16-11-2023 дата публикации

Arrayed waveguide grating device

Номер: WO2023218406A1
Автор: Senming Gong, Shuyu Zhang, Taizhong Huang, Zhanqiao ZENG
Принадлежит: Molex, LLC

[0044] An arrayed waveguide grating device comprises a substrate, an arrayed waveguide grating chip, and a pivoting member. The substrate comprises a first plate portion and a second plate portion which are separated; the first plate portion and the second plate portion are made of the same material; the arrayed waveguide grating chip comprises an input planar waveguide; the input planar waveguide comprises a first part disposed at the first plate portion of the substrate and a second part disposed at the second plate portion of the substrate; and the pivoting member is made of a material different from that of the substrate and connects the first plate portion and the second plate portion of the substrate, so that the first plate portion and the second plate portion are movable relative to each other.

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Номер записи: 35
19-06-2023 дата публикации

Use of interferon alpha-inducible protein 6 (ifi6) and medicine

Номер: NL2029972B1
Автор: Jia Huimin, Jiang Sheng, LIU Pengfei, ZHANG Shuyu
Принадлежит: China Nat Nuclear Corporation 416 Hospital, Univ Sichuan

The present disclosure provides use of an interferon alpha-inducible protein 6 (IFI6) and a medicine, specifically use of an IFI6 in a medicine for prevention and/or treatment of a skin cell radiation injury, and a medicine containing the IFI6. Specifically, the present disclosure is achieved by constructing an overeXpression strategy of the IFI6. The overeXpression of the IFI6 has a preventive and therapeutic effect on the skin cell radiation injury of human, and can enhance anti-apoptosis and cell proliferation abilities after radiation. An IFI6 overeXpression lentivirus or a medicine containing the IFI6 overeXpression lentivirus can be used for prevention and treatment of the human skin radiation injury. The lentivirus or the medicine has important significance and value in treatment of nuclear and radiation accidents and nuclear emergencies, and in reducing skin radiation injury of tumor radiotherapy patients.

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Номер записи: 36
18-01-2024 дата публикации

Use of compound in preparation of medicament for prophylaxis and treatment of inflammatory tissue damage

Номер: US20240016806A1
Автор: Fenghao Geng, Jianhui Chen, Shuyu Zhang, Xiaoqian Li
Принадлежит: Nuclear Industry 416 Hospital, West China Second University Hospital of Sichuan University

The present disclosure relates to use of a compound in preparation of a medicament for prophylaxis and treatment of inflammatory tissue damage. The present disclosure provides use of a compound in preparation of a medicament for prophylaxis and treatment of tissue damage, and the compound has a structure represented by formula I. The compound having the structure represented by formula I provided by the present disclosure can inhibit transcriptional activity of interferon regulatory factor 1 (IRF1), have prophylactic and therapeutic effects on tissue damage, enhance cell proliferation ability after tissue cell injury, and repair injured tissues. The compound having the structure represented by formula I provided by the present disclosure has important significance and application value in the preparation of the medicament for prophylaxis and treatment of tissue damage, particularly in the preparation of a medicament for inflammatory injuries of skin tissues induced by radiation and/or oxidation.

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Номер записи: 37
24-01-2024 дата публикации

Use of compound in preparation of medicament for prophylaxis and treatment of inflammatory tissue damage

Номер: GB2620809A
Автор: Chen Jianhui, Geng Fenghao, LI Xiaoqian, ZHANG Shuyu
Принадлежит: West China Second Univ Hospital Sichuan Univ, West China Second University Hospital of Sichuan University

(I) A medicament for the prophylaxis and treatment of inflammatory tissue damage, wherein the medicament comprises a compound of formula (I) and pharmaceutical excipients, is provided. Preferably the tissue damage is caused by excessive inflammatory response activated by interferon regulatory factor 1 (IRF1). Preferably the tissue damage is skin tissue damage, particularly ionizing radiation-induced skin injury, oxidative skin injury, virus-induced skin injury or ionizing radiation-induced lung tissue injury. The medicament may be in the form of an injection, an ointment, or an aerosol. The compound of formula I can inhibit transcriptional activity of interferon regulatory factor 1 (IRF1).

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Номер записи: 38
04-07-2024 дата публикации

Ceramic powered steel shot magnetic sweeper apparatus

Номер: US20240216927A1
Автор: Brian Weber, Shuyue ZHANG
Принадлежит: Bluestreak Equipment Inc

A continuous discharge ceramic powered steel shot magnetic sweeper apparatus is disclosed. The magnetic sweeper apparatus consists of at least one handle, a frame, support wheel(s), a frontal debris bin, drive wheels, a finned tube housing a ceramic magnetic assembly. The ceramic magnetic assembly comprises a sealed magnetic drum and rotating non-ferrous finned tubes. The magnet is continuously cleaned off as the magnetic sweeper apparatus is pushed forward. Magnetic debris accumulates on the magnet assembly and is deposited in the frontal debris bin. The magnetic sweeper apparatus design utilizes field differences created by the magnet position and angle to achieve the automatic pick-up and drop-off of debris at different locations of the drum. Furthermore, the apparatus aims to solve this high-cost rare earth magnet problem by using lower cost ceramic magnets as an alternative.

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Номер записи: 39
04-07-2024 дата публикации

Magnetic vertical axis rotary clean off attachment apparatus

Номер: US20240215793A1
Автор: Brian Weber, Shuyue ZHANG
Принадлежит: Bluestreak Equipment Inc

A continuous discharge magnetic sweeper apparatus with a vertical axis rotary clean off attachment. The main magnetic sweeper consists of a handle, a back wheel, a frontal debris bin, a drive wheel and a finned drum housing a magnetic assembly. Magnetic debris is attracted by magnet assembly, accumulates on the finned drum and is deposited in the frontal debris bin. The vertical axis rotary clean off attachment connects to the magnetic sweeper and consists of a main frame body, a mounting feature, a support wheel, a rotary cap and a finned driving wheel. The finned driving wheel is a hollow finned wheel driven by contact with a wall, assisting the magnetic field to move shot from the wall side into the main sweeper's range to be picked up by the main sweeper apparatus.

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Номер записи: 40