24-07-2013 дата публикации
Номер: CN103214540A
Принадлежит:
The invention relates to a sodium fusidate crystal and a preparation method thereof. The X-ray powder diffraction spectrum characteristic peaks of the sodium fusidate crystal newly provided by the invention, represented by 2theta+/-0.2 degrees, are at 6.960, 7.117, 8.180, 8.355, 11.895, 14.460, 15.176, 16.389, 16.574, 24.837, 28.967 and 36.344. The preparation method comprises the following steps of: 1) dissolving fusidic acid in a low alcohol solution to obtain a sodium fusidate solution; 2) feeding an ethyl acetate solution into the sodium fusidate solution to crystallize sodium fusidate, and collecting a solid phase; and 3) drying the solid phase, thus obtaining a sodium fusidate crystal. The sodium fusidate crystal provided by the invention has the advantages of being glittering and translucent in appearance, uniform in granule, stable in crystal form, favorable for sub-package and storage, and the like. The method provided by the invention has the advantages that the prepared sodium ...
Подробнее