Active Agent Delivery Devices and Methods for Using the Same

Active agent delivery devices are provided. Aspects of the devices include an active agent delivery component having an active agent delivery system; and an actuator component, where the active agent delivery component is release-ably engaged to the actuator component. The actuator component includes an active agent delivery system actuator. Either or both components may contain one or more elements of a pain mitigation system and/or a smart device system, e.g., an identifier and identifier reader. Also provided are methods of using the devices. 115-. (canceled)16. An active agent delivery device for delivering a therapeutic agent to a target tissue delivery site , the device comprising:(a) an active agent delivery component comprising an active agent delivery system comprising a needle; and (i) a body having a proximal end and a distal end;', '(ii) an active agent delivery system actuator configured to actuate the active agent delivery system; and', '(iii) a cooling system comprising a cold element configured to maintain a temperature of the target tissue ranging from about +5 to −80° C.;, '(b) an actuator component comprisingwherein the active agent delivery component is release-ably engaged to the distal end of the actuator component.17. The device according to claim 16 , wherein the cooling system is configured to mitigate pain at the target tissue delivery site.18. The device according to claim 16 , wherein the cooling system comprises a low-temperature substance.19. The device according to claim 16 , wherein the actuator component comprises a motor.20. The device according to claim 16 , wherein the device is configured to deliver a therapeutic agent.21. The device according to claim 20 , wherein the therapeutic agent is a VEGF antagonist.22. The device according to claim 20 , wherein the therapeutic agent is a complement inhibitor.23. The device according to claim 20 , wherein the therapeutic agent is delivered in a active agent composition.24. The device ...

Internally ridged heat transfer tube

Active agent delivery devices and methods for using the same

Active agent delivery devices are provided. Aspects of the devices include an active agent delivery component having an active agent delivery system; and an actuator component, where the active agent delivery component is release-ably engaged to the actuator component. The actuator component includes an active agent delivery system actuator. Either or both components may contain one or more elements of a pain mitigation system and/or a smart device system, e.g., an identifier and identifier reader. Also provided are methods of using the devices.

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