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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 7. Отображено 7.
14-04-2010 дата публикации

Acyl thiourea compound containing pyrazinyl hydrazine and preparation method and application thereof

Номер: CN0101693696A
Автор: Fu Ying, Xiao Caiqin, Hu Xuemei, Wang Mingzhu, Zhang Huaiyuan
Принадлежит:

The invention provides an acyl thiourea compound containing pyrazinyl hydrazine, which is prepared by the following steps: firstly converting organic acid into acyl chloride; then reacting the acyl chloride with ammonium thiocyanate in a non-protonic solvent in the presence of a phase transfer catalyst to obtain acyl isorhodanic ester; and then reacting the acyl isorhodanic ester with the pyrazinyl hydrazine. The acyl thiourea compound is simultaneously provided with the functional groups of pyrazine and thiourea substances, has a certain drug effect on tuberculosis and diabetes, and can also play a certain regulating action on plant growth. Primary bioactivity tests show that the acyl thiourea compound plays a certain regulating action on the growth of dicotyledonous rapeseeds.

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Номер записи: 1
14-04-2010 дата публикации

Method for synthesizing 1,2-diphenylethylene compounds

Номер: CN0101693642A
Автор: Fu Ying, Hu Xuemei, Wang Mingzhu, Xiao Caiqin, Zhang Huaiyuan, Liu Yan, Huang Danfeng, Hu Yulai
Принадлежит:

The invention provides a new method for synthesizing 1,2-diphenylethylene compounds, which comprises the following steps: additively reacting aromatic aldehyde with a bisbenzyl zinc reagent in the molar ratio of 1:1-2.5:1 at the temperature of minus 80 DEG C to plus 80 DEG C for 2-16 hours in a non-protonic organic solvent under nitrogen protection by using Lewis acid as a catalyst, adding acid for quenching, and obtaining a target compound through separation. The invention adopts the bisbenzyl zinc reagent with higher reactive activity for replacing a benzyl zinc halide regent with lower reactive activity, thereby effectively increasing the reaction velocity and improving the reaction efficiency; the invention adopts the Lewis acid as the catalyst instead of a valuable transition metal complex catalyst, thereby lowering the synthetic cost and improving the yield of products.

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Номер записи: 2
29-08-2012 дата публикации

One-pot method for synthesizing N-methylnitrone compounds

Номер: CN0101514169B
Автор: CAIQIN XIAO, YING FU, XUEMEI HU, MINGZHU WANG, YANHUA LIU, HUAIYUAN ZHANG, JIAO LI, FEI PEI, XIAO CAIQIN, FU YING, HU XUEMEI, WANG MINGZHU, LIU YANHUA, ZHANG HUAIYUAN, LI JIAO, PEI FEI
Принадлежит:

The invention provides a one-pot method for synthesizing N-methylnitrone compounds, comprising the steps of: reducing nitromethane at first with a metal reducing agent, adding aromatic aldehyde directly into a reaction solution for heated reflux to obtain a target product having high yield. The invention uses the nitromethane and the aromatic aldehyde as raw materials, takes organometallic reagents such as zinc, tin and the like as the reducing agent, and employs a one-spot method for the heated reflux to directly synthesize the N-methylnitrone compounds. The method provided by the invention has the characteristics of less synthesis procedures, simple technique, easy operation, easily-available and inexpensive raw materials, mild reaction conditions, low synthesis cost, good product quality and high yield, as well as is an efficient and convenient method for synthesizing the N-methylnitrone compounds.

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Номер записи: 3
11-08-2023 дата публикации

Water quality high-pressure purification treatment equipment

Номер: CN116573742A
Автор: XIAO CAIQIN, FAN WENBO
Принадлежит:

The invention belongs to the technical field of purification equipment, and discloses water quality high-pressure purification treatment equipment which comprises a supporting frame, purification treatment equipment and a water inlet pipe, the purification treatment equipment is in bolted connection with the water inlet pipe, and the top of the purification treatment equipment is movably sleeved with a piston; blocking units are hinged to the upper and lower sides of one end, close to the water inlet pipe, of the inner cavity of the purification treatment equipment, and movable units are movably connected to the upper and lower sides of one end, close to the blocking units, of the inner cavity of the purification treatment equipment. Through cooperation of structures such as the moving unit and the rotating unit, the effect of pre-treating and purifying water quality during water taking is further achieved, the inner end of the water taking device can be matched with the bottom of the purification ...

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Номер записи: 4
15-06-2011 дата публикации

Chalcone-containing acylthiourea compounds and preparation method and use thereof

Номер: CN0102093274A
Автор: YING FU, CAIQIN XIAO, YANSHOU YANG, YAOJUAN CHEN, KANGQING CAI, LIANG AN, FU YING, XIAO CAIQIN, YANG YANSHOU, CHEN YAOJUAN, CAI KANGQING, AN LIANG
Принадлежит:

The invention provides chalcone-containing acylthiourea compounds and a preparation method and use thereof and belongs to the technical field of chemical synthesis. The compounds are prepared by reacting acyl chloride with ammonium thiocyanate in the presence of a phase transfer catalyst in a protonic solvent to obtain acylisosulfocyante, reacting acylisosulfocyante with aminoacetophenone to obtain N-benzoyl-N'-acetylphenylthiourea, and performing condensation of N-benzoyl-N'-acetylphenylthiourea and aromatic aldehydes under an alkaline condition to obtain target compounds. The chalcone-containing acylthiourea compounds prepared by the invention have carbonyl, vinyl, acyl and thiourea functional groups and belong to bioactive materials having multiple functional groups. Initial bioactivity tests show that the materials have regulating effect on the growth of dicotyledonous rape seeds.

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Номер записи: 5
29-08-2023 дата публикации

Preparation method of subuprofen

Номер: CN116655587A
Автор: XIAO CAIQIN, FAN WENBO, LI ZHIJIE, ZHU LIJUN
Принадлежит:

The invention relates to a preparation method of subuprofen, which comprises the following steps: (1) in a nitrogen atmosphere, taking 2-thiophenecarboxaldehyde as a substrate, pivalaldehyde as an oxidant and a 4-vinyl phenyl zinc reagent as a nucleophilic reagent, carrying out addition oxidation reaction in an organic solvent I at room temperature to prepare heterocyclic aromatic ketone, adding an organic solvent II for extraction, filtering, washing and drying to obtain the subuprofen. Carrying out column chromatography separation to prepare an intermediate (thiophene-2-yl)-2-(4-vinyl phenyl) ketone; (2) adding a catalyst, an organic phosphine ligand, an organic solvent III and the intermediate (thiophene-2-yl)-2-(4-vinyl phenyl) ketone into a high-pressure reaction kettle to obtain a mixed solution; and adding an organic solvent III and a strong acid solution into the mixed solution at room temperature, introducing CO, carrying out a hydrocarbonylation reaction to obtain a crude subuprofen ...

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Номер записи: 6
26-08-2009 дата публикации

One-pot method for synthesizing N-methylnitrone compounds

Номер: CN0101514169A
Автор: FU YING, WANG MINGZHU, HU XUEMEI, LIU YANHUA, XIAO CAIQIN, ZHANG HUAIYUAN, LI JIAO, PEI FEI, YING FU, MINGZHU WANG, XUEMEI HU, YANHUA LIU, CAIQIN XIAO, HUAIYUAN ZHANG, JIAO LI, FEI PEI
Принадлежит:

The invention provides a one-pot method for synthesizing N-methylnitrone compounds, comprising the steps of: reducing nitromethane at first with a metal reducing agent, adding aromatic aldehyde directly into a reaction solution for heated reflux to obtain a target product having high yield. The invention uses the nitromethane and the aromatic aldehyde as raw materials, takes organometallic reagents such as zinc, tin and the like as the reducing agent, and employs a one-spot method for the heated reflux to directly synthesize the N-methylnitrone compounds. The method provided by the invention has the characteristics of less synthesis procedures, simple technique, easy operation, easily-available and inexpensive raw materials, mild reaction conditions, low synthesis cost, good product quality and high yield, as well as is an efficient and convenient method for synthesizing the N-methylnitrone compounds.

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Номер записи: 7