Information sharing method, apparatus, and computer device

Load characteristic classification and synthesis method based on frequency domain indexes

The invention discloses a load characteristic classification and synthesis method based on frequency domain indexes. Firstly, electrical transformer districts to be classified are obtained form a monitoring control and data acquisition system, data are preprocessed, normalization processing is conducted the data, the data are represented through per unit values, an average is obtained according to the data in one or more weeks, and a typical daily load curve is obtained; then, based on a defined frequency domain index description system, an appointed clustering method is adopted for obtaining electrical transformer district types similar to frequency domain characteristic parameters, and finally typical load curves of classified users and frequency domain index description sets of the typical load curves are obtained. Compared with traditional load classification and synthesis methods, the load characteristic classification and synthesis method has the advantages that the number of data ...

Breeding method for shortening float periods of urechis unicinctus larvae

The invention discloses a breeding method for shortening float periods of urechis unicinctus larvae. The breeding method particularly includes feeding isochrysis 3011 to the urechis unicinctus larvae from the third day to the seventh day after the urechis unicinctus larvae are fertilized, and keeping the temperatures at 15.5-16 DEG C; keeping the water temperatures at 16.5-17 DEG C from the seventh day to the twelfth day; keeping the water temperatures at 17.5-18 DEG C from the thirteenth day to nineteenth day and changing 1/2 volumes of water twice on a daily basis; feeding feed four times on a daily basis from the seventh day to nineteenth day. The isochrysis 3011 is initial feed, and the feeding quantities of the initial feed is 40ml/m<3>d. Formulas and usage quantities of the feed in different procedures from the seventh day to nineteenth day are different from one another. The breeding method has the advantages that the metamorphosis and settlement time of the urechis unicinctus larvae ...

Wheat seed coating agent

The invention relates to a wheat seed coating agent. The wheat seed coating agent comprises sodium hexametaphosphate, phoxim, guar gum, polyurea, copper hydroxide, empenthrin, kasugamycin, modified starch, gibberellin, agar, forchlorfenuron and micro-element fertilizer. The wheat seed coating agent has a low price. The bactericide and pesticide in the coating agent can effectively prevent insert eating and mildewing. Gibberellin in the coating agent can promote seed germination. The micro-element fertilizer in the coating agent provides trace elements for wheat seed germination. The wheat seed coating agent greatly improves a seed survival rate.

Dynamic control method for playing point in live broadcast of streaming media data

The invention provides a dynamic control method for a playing point in live broadcast of streaming media data. The position of a local playing point of a client can be dynamically controlled; when streaming media of the client are played not fluently, the set time of the local playing point of the client is stopped so as to wait for enough data accumulation in a buffer area, therefore the demand of continuous playing of the client is met; meanwhile, the playing condition of the client is monitored, and when disfluent playing occurs again, a data acquisition server is switched; when data in the buffer area satisfy the continuous playing of the client, the local playing point of the client is switched into a real-time playing point of the server, or else the current playing point of the client is kept to go on playing the streaming media data. Through the technical scheme proposed by the invention, the condition that disfluent playing occurs continuously when the streaming media are played ...

Anti-stain dustproof printing adhesive and preparation method thereof

The invention discloses an anti-stain dustproof printing adhesive which is prepared from the following raw materials in parts by weight: 2-3 parts of sodium hydrogen carbonate, 1-2 parts of dispersing agent MF, 6-8 parts of polyvinyl alcohol, 2-3 parts of itaconic acid, 14-16 parts of trimethylolpropane trimethacrylate, 40-45 parts of bisphenol A epoxy acrylate, 10-12 parts of tripropylene glycol diacrylate, 12-14 parts of propylene carbonate, 4-5 parts of silica sol, 5-7 parts of methylacrylic acid, 9-12 parts of isooctyl methacrylate, 1-2 parts of ammonium persulfate, 4-5 parts of auxiliaries and 70-75 parts of water. By being added with the silica sol, the adhesive disclosed by the invention has an excellent dustproof anti-stain effect as well as the characteristics of high transparency, hot water resistance, weather resistance, drug resistance, softness, good toughness and high fastness; the application range of the adhesive disclosed by the invention is wide, and the advantage of good ...

Sending terminal, receiving terminal directly realizing spread-spectrum ultra-wideband and method thereof

The invention relates to a sending terminal for implementing DS-UWB. The invention comprises: an encoder for decoding data frames to send, a spread spectrum modulator capable of performing PN sequence spectrum spreading and BPSK modulating to the data outputted by the decoder, a waveshaper capable of performing wave shaping to the data outputted by the spread spectrum modulator to get digital baseband waveshape, a digital-to-analog converter capable of performing digital-to-analog conversion to the digital baseband waveshape outputted by the waveshaper to get simulative baseband waveshape, a low pass filter capable of performing low pass filtering to the simulative baseband waveshape outputted by the digital-to-analog converter; an up-converter capable of performing up conversion to the simulative baseband waveshape outputted by the low pass filter, and an RF signal emission processor capable of performing emission processing to the signal outputted by the up-converter. The sending terminal ...

Raw material screening device for mechanical parts

The invention discloses a raw material screening device for mechanical parts, and relates to the technical field of raw material screening, the raw material screening device comprises a bottom frame, vibration springs and a screening barrel, the screening barrel is connected to the bottom frame through the vibration springs, a discharging channel is connected to the side wall of the screening barrel, and a vibrator is further installed on the side face of the screening barrel; a screen is connected into the screening barrel, a discharging assembly used for storing and discharging materials is arranged on the lower side of the screen, a feeding assembly used for feeding materials upwards is arranged below the discharging assembly, and an impurity removing assembly used for removing impurities of screened materials is installed between the feeding assembly and the discharging assembly. A driving mechanism used for driving the feeding assembly to move up and down is installed at the bottom ...

Visible light infrared image fusion method based on least square filtering

The invention relates to a visible light infrared image fusion method based on least square filtering, belongs to the technical field of image processing, and solves the problems that in an image fused by an existing visible light infrared image fusion method, detail parts with obvious contrast but low pixel intensity are lost, and the edge of the image is blurred. The invention discloses a visible light infrared image fusion method based on least square filtering. The method comprises the following steps of solving a detail layer image of a visible light grayscale image after least square filtering; obtaining a detail layer average value for the visible light least square detail layer and the fusion result detail layer; and fusing the average values of the background layer and the detail layer of the fusion result to obtain a final fusion result image. According to the method, detail information with obvious contrast and low pixel intensity value in an image area is reserved; according ...

Forward-installed mold structure for ejection demolding of cold runner

The invention relates to a forward-installed mold structure for ejection demolding of a cold runner, and belongs to the technical field of injection molds, the forward-installed mold structure comprises an injection mold, the injection mold comprises a male mold core and a female mold core, a straight ejection block used for ejecting a product is arranged on the male mold core, an inverted buckle groove is formed in the straight ejection block, and the cold runner is jointly defined by the straight ejection block, the inverted buckle groove and the male mold core; and the ejection mechanism comprises a material pushing piece arranged in the straight ejection block and an elastic piece used for driving the material pushing piece to move towards the reversing groove, one part of the end, away from the elastic piece, of the material pushing piece abuts against the male die core, and the other part of the end, away from the elastic piece, of the material pushing piece makes contact with the ...

Lofting method, device and equipment and storage medium

The invention discloses a lofting method, device and equipment and a storage medium. The lofting method comprises the steps that an image shot by lofting equipment and current position information of the lofting equipment are obtained, and the image comprises depth information of the lofting equipment and the ground; according to the image and the current position information, geographic projection information of the ground is determined, the geographic projection information is used for indicating three-dimensional position information of the ground, and the three-dimensional position information comprises height information; according to the geographical projection information and the position information of the target lofting point, determining whether a ground transformation point needs to be used; when it is determined that the ground transformation point needs to be used, path information between the current position information of the lofting equipment and the position information ...

Precursors for lithium transition metal oxide cathode materials for rechargeable batteries

CHEMILUMINESCENCE IMMUNOASSAY KIT FOR ADIPONECTIN, AND PREPARATION METHOD AND USE THEREOF

Provided are a chemiluminescence immunoassay kit for adiponectin, and a preparation method and a use thereof. The chemiluminescence immunoassay kit for adiponectin comprises: a solid carrier coated with an adiponectin monoclonal antibody; and an adiponectin monoclonal antibody marked with a chemiluminescence marker.

Huperzine A preparations for eyes and application thereof

The invention relates to Huperzine A preparations for eyes and application thereof. The Huperzine A preparations for the eyes can be applied to preparing medicaments for preventing and treating glaucoma, increase of intraocular pressure and eye problems concomitant with retinal ganglion cell injury; and the preparations for the eyes are Huperzine A eye drops and a Huperzine A in-situ-gel for eyes. The invention has the advantages that: the Huperzine A eye drops and the Huperzine A in-situ-gel for eyes are successfully developed, and the two formulations are convenient for ophthalmic patients to use. The Huperzine A in-situ-gel for eyes is liquid with good fluidity in vitro; when the Huperzine A in-situ-gel is dropped into eyes, the formulation is easily controlled accurately and the use is convenient; and after the Huperzine A in-situ-gel is dropped into eyes, the Huperzine A in-situ-gel can be uniformly spread to form a gel, stays in the eyes for a long time, is not easily lost to be absorbed ...

Welding gun of ultra narrow gap and welding method

The invention discloses a welding gun of ultra narrow gap. The two plate-type conductive mouths of the welding gun are both provided with cambered grooves, and the welding wire 3 is clamped between the cambered grooves of the two plate-type conductive mouths. A bearing (16) is arranged on an electrode connection block (17). The bearing (16) is arranged on a rotation shaft fixed on an insulation board (19). The electrode connection block (17) can rotate relative to the insulation board (19) about the axis of the bearing (16). A regulation spring (18) is arranged on the electrode connection block (17). One end of the regulation spring is arranged on the upper part of the electrode connection block (2). The insulation board on one side of the plate-type conductive mouth (4) is provided with a solder addition pipe (5). The insulation board on the other side of the plate-type conductive mouth (15) is provided with a solder collection pipe (14). The nearby parts of the solder addition pipe (5 ...

Anti-plugging method and device of constructed wetland

The invention discloses an anti-plugging device of a constructed wetland. The anti-plugging device is characterized by comprising a water collection area substrate and a wetland substrate which are distributed in a vertical current constructed wetland from down to up, wherein wetland plants are grown on the wetland substrate; a pneumatic tube is installed in the wetland substrate; the horizontal section of the wetland substrate faces downwardly and provided with an aeration branch pipe in parallel; the end head of the aeration branch pipe is provided with an aeration head, and the aeration head is located in the middle of the wetland in a vertical direction; one end of the pneumatic tube extending out of the wetland substrate is connected with a gas pump and provided with a valve; and the water collection area substrate is made of gravel, and the wetland substrate is made of coarse sand. The air passes through the pneumatic tube by the gas pump and then is output from the aeration branch ...

Method for cultivating gastrodiaelata via artificial cut logs

The invention relates to a gastrodiaelata planting technology, and particularly relates to a method for cultivating gastrodiaelata via artificial cut logs. The method comprises the following steps: selecting broad-leaf branches and sawing into cut logs, sterilizing the cut logs at a temperature of 120-125DEG C, binding 20 cut logs into a bundle after cooling and putting the bundle in a sealing bag, putting the bound cut logs in a culture room of 25DEG C, scattering armillaria strains and humus in the clearances among the cut logs, culturing the armillaria in the culture room of 25DEG C for 45-50 days, taking the cut logs out of the sealing bag and putting in a sandy soil pit, sowing gastrodiaelata seeds in the clearances of bacteria sticks, covering a layer of humus on the gastrodiaelata seeds, sowing a layer of sandy soil on the humus, and watering until the soil moisture is 55-58%. According to the method for cultivating gastrodiaelata via artificial cut logs, the gastrodiaelata cultivation ...

Composite preparations for preventing and treating type II diabetes

The invention belongs to the medical field and the chemical field of microelement and relates to a compound preparation for preventing and curing II type diabetes. The invention uses chromium, manganese, cooper and zinc microelements as the active ingredients for preparing the compound preparation, with subsidiary capable of being added according to the need so as to further prepare a medicine or various health-care products. The preparation enables the blood sugar to quickly enter the cells so as to eliminate the blockage of the blood sugar in the veins, thus eliminating the risks of high blood sugar content and complications. The preparation can adjust the blood sugar content in two directions so as to prevent hypoglycemia. The use of the preparation together with curing medicine can effectively reduce the sugar content and better and delay the development of various complications. The preparation is not obvious in side effect, simple and convenient in production and environment protective ...

Web page dynamic updating method, system and apparatus

The present invention relates to the communication field and provides a dynamic update method of web pages and a system and equipment. The method comprises following procedures: A. according to a request sent out by a client, a server processes stored paper data and feedbacks a message comprising a processing result; B. after the client receives the message, the client carries out corresponding operation on a node tree structure of the stored page data according to the processing result of page data by the server; C. according to the node tree structure, the client updates the local stored page data and uses the total updated page data to draw a web page to display on a user interface. The invention uses the node tree structure to store the requested page data through the client; when thepage data is processed by the server, the node tree structure is used to update the local page data synchronously to ensure the consistency of data between the server and the client.

Power supply uninterruptible operation generator with embedded matched integrated equipment

The invention discloses a power supply uninterrupted operation power generator embedded with matched integrated equipment, which comprises a power generator, a control box is arranged at the end part of the power generator, the control box is embedded into the power generator, a cabinet door is arranged at the position, corresponding to the control box, of the side wall of the power generator, and the cabinet door is rotationally connected with the power generator. The control box is internally provided with an integrated control device, the integrated control device comprises a nuclear phase mechanism, a detection control mechanism, an operation mechanism, a display mechanism and a connection mechanism, through the above technical scheme, the control box is embedded in the generator, and the nuclear phase mechanism, the detection control mechanism, the operation mechanism, the display mechanism and the connection mechanism are installed in the control box. And integrated control equipment ...

Hot runner glue feeding device for plastic product injection molding

The invention relates to a hot runner glue feeding device for plastic product injection molding, and belongs to the technical field of injection molds. Comprising a hot nozzle, the hot nozzle comprises a hollow hot nozzle body, the periphery of the hot nozzle body is surrounded by a heating ring for heating the hot nozzle body, the interior of the hot nozzle body is connected with a hollow heat conduction pipe, and an outlet of the heat conduction pipe extends towards the outlet direction of the hot nozzle body; the temperature controller comprises a cooling water jacket surrounding the periphery of the hot nozzle, a heat conduction insert surrounds the periphery of the cooling water jacket, and a temperature control cavity for controlling the temperature of an outlet of the hot nozzle is formed between the cooling water jacket and the heat conduction insert. According to the hot runner glue feeding device, when cold materials are generated on the surface of a product at the front end of ...

Infrared imaging single-lens optical system

The invention provides an infrared imaging single-lens optical system. The system comprises an outer ring lens and an inner ring lens, the outer ring lens is arranged on the outer side of the inner ring lens in a sleeving manner; object light enters the front surface of the outer ring lens, enters the rear surface of the outer ring lens after being transmitted by the front surface of the outer ring lens, is reflected to the front surface of the inner ring lens through the rear surface of the outer ring lens, and is reflected to the rear surface of the inner ring lens through the front surface of the inner ring lens. And finally, after being transmitted by the rear surface of the inner ring lens, the light is imaged on an image plane. The technical problems that in the prior art, a reflective/catadioptric long-wave infrared optical system is difficult to athermalize, a supporting structure is complex, batch production is not facilitated, the production cost is high, the installation and ...

Automatic blanking equipment for mobile phone middle frame

The invention aims to provide the mobile phone middle frame automatic discharging equipment which is full-automatic in operation, high in working efficiency and capable of completing classified discharging. The device comprises a cabinet, and an empty tray feeding mechanism, a qualified product discharging mechanism, a defective product discharging mechanism, a tray transferring mechanism, a material taking manipulator and a product conveying mechanism which are arranged on the cabinet. The invention relates to the technical field of automatic production.

Information screening method and device and computer equipment

The invention relates to an information screening method and device, computer equipment, a storage medium and a computer program product. The information screening method comprises the following steps: acquiring to-be-screened information contained in a website corresponding to a target website; according to a pre-stored website identifier, extracting a to-be-identified website contained in a website corresponding to the target website from the to-be-screened information; according to a preset keyword form, determining an identification result of preset type information in to-be-identified information contained in a website corresponding to the to-be-identified website; and screening the websites to be recognized according to the recognition result. Through the setting, waste of manpower and material resources caused by manual screening of irrelevant websites is avoided, the monitored websites better meet user requirements, the processor can automatically update and expand the websites ...

AMIDOPYRAZOLE INHIBITORS OF INTERLEUKIN RECEPTOR-ASSOCIATED KINASES

This invention relates to amidopyrazole compounds that are inhibitors of Interleukin receptor-associated kinases, in particular IRAK-4, and are useful in the treatment of cellular proliferative diseases, for example, cancer, hyperplasia, restenosis, cardiac hypertrophy, immune disorders and inflammation. 2. The compound of wherein Ris aryl claim 1 , wherein said aryl group is optionally substituted with one or two substituents selected from the group consisting of halo claim 1 , cyano claim 1 , R claim 1 , Ccycloalkyl claim 1 , Caminoalkyl claim 1 , Chydroxyalkyl claim 1 , OR claim 1 , NRR claim 1 , NRCOR claim 1 , NRSOR claim 1 , SONRR claim 1 , and CONRR claim 1 , or a pharmaceutically acceptable salt thereof.3. The compound of wherein Ris aryl claim 2 , wherein said aryl group is optionally substituted with Ror OR claim 2 , or a pharmaceutically acceptable salt thereof.4. The compound of wherein Ris phenyl claim 3 , wherein said phenyl group is optionally substituted with Ror OR claim 3 , or a pharmaceutically acceptable salt thereof.5. The compound of wherein Ris heteroaryl claim 1 , wherein said heteroaryl claim 1 , group is optionally substituted with one or two substituents selected from the group consisting of halo claim 1 , cyano claim 1 , oxo claim 1 , hydroxyl claim 1 , imino claim 1 , hydroxyimino claim 1 , R claim 1 , OR claim 1 , O(Ccycloalkyl) claim 1 , (C═O)OR claim 1 , SOR claim 1 , SOR claim 1 , NRR claim 1 , SONRRand NRSOR claim 1 , or a pharmaceutically acceptable salt thereof.6. The compound of wherein Ris heteroaryl claim 1 , wherein said heteroaryl claim 1 , group is optionally substituted with one or two substituents selected from the group consisting of halo claim 1 , cyano claim 1 , oxo claim 1 , hydroxyl claim 1 , imino claim 1 , hydroxyimino claim 1 , R claim 1 , OR claim 1 , O(Ccycloalkyl) claim 1 , (C═O)OR claim 1 , SOR claim 1 , SOR claim 1 , NRR claim 1 , SONRRand NRSOR claim 1 , or a pharmaceutically acceptable salt thereof.7. The ...

POLYCYCLIC INDAZOLE DERIVATIVES AND THEIR USE AS ERK INHIBITORS FOR THE TREATMENT OF CANCER

Disclosed are the ERK inhibitors of formula 1.0: (Chemical formula should be inserted here as it appears on abstract in paper form) and the pharmaceutically acceptable salts, esters and solvates thereof. Q is a piperidine or piperazine ring that can have a bridge or a fused ring. The piperidine ring can have a double bond in the ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1Ø ...

A adjust formula solar charging lighting device for sextant scale

The utility model relates to an adjust formula solar charging lighting device for sextant scale, include the disk body, disk body lower extreme fixedly connected with surface has the sliding bracket of graduation apparatus, and pilot hole and lower pilot hole have been offered to the disk body surface, goes up the pilot hole and is T type structure with lower pilot hole cross section, and the disk body back is provided with the handle of conveniently handling the sextant. The utility model discloses an adjust formula solar charging lighting device for sextant scale passes through adjusting bolt and the adjustment handle of hinged joint mechanism in the angle and the position at the disk body back, makes things convenient for the more effectual conversion electric energy of solar charging board at the handle back, and the convenient detachable lighting device who gives the scale surface charges, promotes lighting device's duration greatly, makes things convenient for ocean navigation operation ...

Novel sapphire vacuum system

The utility model relates to a novel sapphire vacuum system is aimed at providing in the sapphire crystal growth furnace field. Among this vacuum system: main oven chamber connects to first baffle valve through main vacuum line, and first baffle valve is taken out pipeline, second baffle valve, second owner through first owner in proper order and is taken out pipeline, bellows joint to vortex sheet pump, and first owner takes out the pipeline and still loops through first roughing pipe, vacuum electromagnetism needle valve, second roughing pipe and connect to the second owner and take out the pipeline, the exit end of first baffle valve meets with the diffusion pump entry end, and the exit end of diffusion pump connects to the second owner through diffusion pump branch road, third baffle valve and takes out the pipeline. The utility model discloses a three routes the bleed switching and the control in route, can prevent a large amount of dust material along with in the air current gets ...

Preparation method of traditional Chinese medicine for treating acute lymphadenitis

A method for preparing a traditional Chinese drug for treating acute lymphadenitis belongs to the technical field of the traditional Chinese medicine preparation method. Anti-infective drugs such as (1) penicillin are used for treating the acute lymphadenitis, which easily causes allergic reaction, especially anaphylactic shock, and the life can be endangered in the absence of timely emergency treatment; the technical proposal of the method is as follows: Chinese violet, root of muskroot-like semiaquilegia, forsythia fruit, sargentgloryvine, ampelopsis root, paris rhizome, Chinese lobelia, discolor cinquefoil herb, herb of commom canscora, Japanese cayratia herb, root of Japanese raspberry, honeysuckle flower, dandelion, isatis leaf, isatis root, patrinia, herb of heartleaf houttuynia, wintercherry fruit, globethistle root, cyrtomium rhizome, purslane, barberry root, beggarticks and yellow wine are taken out and soaked in water, and then decocted by mild fire to obtain liquid medicine, ...

Crucian feed

The invention relates to a crucian feed. The crucian feed comprises the following components: ants, cattle bone meal, egg yolk, calcium gluconate, magnesium stearate, folium isatidis, sticktight, sealwort, herba lysimachiae, bran and maggot powder. The crucian feed provided by the invention is prepared from high-protein raw materials; meanwhile, the feed is rich in mineral components, such as calcium and magnesium, so that required minerals are provided for the growth of crucian; the growth of crucian is promoted; moreover, the ants and the maggots are rich in protein content and have complete types of amino acids, so that the crucian feed facilitates the growth of the crucian.

High-voltage pulse power supply capable of keeping current constant at short circuit

The invention provides a high-voltage pulse power supply capable of keeping current constant at a short circuit. The high-voltage pulse power supply consists of a voltage reducing and current limiting circuit, a main loop direct-current power supply, a pulse unit direct-current power supply, a pulse generator, a high-voltage packet, a field effect tube, an insulation porcelain connector, an anodeof a plasma generator and a grounded cathode. In the high-voltage pulse power supply, the voltage reducing and current limiting circuit having a short-circuit current limiting function is arranged atan AC220V power input end and feedback circuits capable of executing negative feedback steps are arranged in a main loop and a pulse unit respectively, so the limitless high-voltage short circuit of the output end is allowed, and a short-circuit current value at the high-voltage short circuit is used as a constant current sustainable by devices in the system.

Water controller by taking municipal alternating current as test signal

The invention relates to a water controller by taking municipal alternating current as a test signal. The water controller consists of a water storage container and a control circuit; a high-water level electrode, a low-water level electrode and a sampling electrode are arranged in the water storage container; the control circuit controls a load by water level control signals sent by the electrodes; when the low-water level electrode or the high-water level electrode is submerged in water, a switch is switched on; when the low-water level electrode or the high-water level electrode is not submerged in water, the switch is switched off; when the water level is lower than the low-water level electrode, the test signal is disconnected, and the load is started; when the water level raises to be higher than the high-water level electrode, the test signal is connected with water through the high-water level electrode, and the load stops; when the water level descends to be between the high-water ...

Broadband beam switching method and device, electronic equipment and storage medium

The invention provides a broadband beam switching method and device, an electronic device and a storage medium, and the method comprises the steps: transmitting a registration request to a plurality of satellites capable of providing a narrowband communication service through a narrowband beam through a terminal device, and building a narrowband communication connection; the terminal equipment determines a target area which is about to enter and needs to switch broadband beams; the terminal equipment determines a target satellite for switching the broadband beam after entering the target area according to the communication parameters; and when entering the target area, the terminal equipment sends a request for switching the broadband beam to the target satellite through the narrowband beam. The target satellite is not searched through a gateway station, decentralization operation of broadband beams is realized, and the beam switching efficiency is improved.

Power distribution line ice coating live-line removing device and method

The invention discloses a power distribution line icing live-line removing device which comprises a rack and a walking mechanism arranged on the rack, the rack is further provided with a line clamping mechanism and a knocking deicing mechanism, the line clamping mechanism is provided with a deicing cutter, and when the line clamping mechanism clamps a line, the knocking deicing mechanism is arranged on the line clamping mechanism. The distance between the deicing cutter and the line is smaller than the distance between the knocking deicing mechanism and the line. The invention further discloses a clearing method of the power distribution line icing electrified clearing device, and the clearing method comprises the following steps: S1, line feeding: the rack is placed on a line through the walking mechanism, and then the line clamping mechanism clamps the line; and S2, deicing: the walking mechanism is started to drive the line clamping mechanism and the knocking deicing mechanism to move ...

Surface enhancement method for 3Cr13 propeller shaft

The invention discloses a method for enhancing the surface of a 3Cr13 propeller shaft. The method comprises the following steps: 1) carrying out cleaning pretreatment on the surface of the 3Cr13 propeller shaft; (2) powder raw materials of all elements of the CoCrFeNiMox alloy are prepared, and x ranges from 0.1 to 1; (3) drying the powder; and (4) the powder is conveyed to a laser cladding head through a powder feeder, and meanwhile, the powder of the cladding head is melted through laser under the protective atmosphere to cover the surface of the 3Cr13 propeller shaft. The hardness of the prepared CoCrNiFeMo high-entropy alloy coating is 2.17 times that of quenched and tempered 3Cr13 of a propeller shaft material, the tensile strength of the CoCrNiFeMo high-entropy alloy coating is improved by 6% compared with that of 3Cr13, the frictional wear performance of the CoCrNiFeMo high-entropy alloy coating is improved by 37.5% compared with that of 3Cr13, the corrosion resistance of the CoCrNiFeMo ...

Doped and coated lithium transition metal oxide cathode materials for batteries in automotive applications

Visualization of graphical representations of log files

A computer-implemented method includes receiving one or more log files. Each of the one or more log files includes one or more logs. The computer-implemented method further includes extracting one or more event records from said one or more logs. The computer-implemented method further includes, for each event record of the one or more event records, determining one or more attributes and one or more dimensions based on the event record, respectively. The computer-implemented method further includes grouping the one or more event records into one or more attribute groups. The computer-implemented method further includes ordering the one or more event records of each of the one or more attribute groups by the one or more dimensions. The computer-implemented method further includes generating one or more graphical representations of the one or more attribute groups. A corresponding computer system and computer program product are also disclosed.

Generating a regulated signal from another regulated signal

An embodiment of a method includes generating a regulated output signal from a regulated intermediate signal in response to a reference signal and the regulated output signal, and generating the regulated intermediate signal from an input signal in response to the regulated output signal and the regulated intermediate signal. By generating one regulated signal (e.g., a regulated output voltage) from another regulated signal (e.g., a regulated intermediate voltage), the magnitude of the ripple component of the one regulated signal may be reduced. Furthermore, by generating the regulated intermediate signal in response to the regulated output signal, the efficiency of the regulation may be increased.

System and method for evaluating performance and evolution ability of network address and identification schemes

In a method, formal descriptions of network address and identification schemes are received. Then validity and completeness of the formal descriptions are verified. The network address and identification schemes are scheduled into a final description after the validity and completeness of the formal descriptions are verified. The final description is resolved into an applicable network address. Then the applicable network address and identification scheme is applied to a test network and the test network runs. The running performance of the test network is measured. The measurements are analyzed and sent to evaluating performance and evolution ability of the network address and identification schemes.

Coagulant capable of improving coupling and sedimentation of fogdrops and dust particles

The invention discloses a coagulant capable of improving the coupling and sedimentation of fogdrops and dust particles, which comprises the following components in percentage by mass: 0.01%-0.10% of fatty alcohol-polyoxyethylene ethers, 0.01-0.10% of cocamidopropyl betaine, 0.01-0.10% of sodium alcohol ether sulphate, 0.10-1.10% of a starch-acrylate grafted copolymer, and the balance of water. An adsorption effect is achieved among hydrophobic groups and dust particles, so that the contact ability of water with the dust particles is increased; dust particles are brought to water, and then fully wetted and settled, so that the efficiency that fogdrops coagulate dust is increased, in such a way, the efficiencies of coupling, coagulation and sedimentation of fogdrops and dust particles can be effectively improved, the wettable seepage velocity of water to dust particles is accelerated, the sedimentation time of dust particles is reduced, and the problem that dust is difficultly condensed and ...

Two wheel drive steel -cable drawing mechanism

The utility model provides a two wheel drive steel -cable drawing mechanism, include frame, first bend wheel, second bend wheel, third bend wheel, motor, action wheel, follow driving wheel and drive chain, action wheel and follow driving wheel pass through waist - round hole and install in the frame, the bend wheel is just fixed in the frame at action wheel and driven round of top for at least three setting, the motor is connected to the action wheel through drive chain, wire rope passes first bend wheel in proper order, keeps the tensioning state from driving wheel, second bend wheel, action wheel, third bend wheel and wire rope. The utility model discloses with wire rope come and go take up the bend wheel with the action wheel, from between the driving wheel, adjust the action wheel, can adjust wire rope's tensile force, the satisfied not traction force requirement of equidimension from the distance between the driving wheel.

Mounting plate assembly for monocrystalline silicon growth furnace

The invention relates to the field of monocrystalline silicon growth furnaces and aims at providing a mounting plate assembly for a monocrystalline silicon growth furnace. The mounting plate assembly for the monocrystalline silicon growth furnace comprises a connector bolt, a mounting plate and switch assemblies, wherein the switch assemblies comprise a switch assembly A and a switch assembly B; the switch assembly A is used for controlling a secondary furnace chamber and a furnace lid of the monocrystalline silicon growth furnace to move or not; the switch assembly B is used for controlling the secondary furnace chamber to move independently or move together with the furnace lid; by matching of the connector bolt and the mounting plate, the secondary furnace chamber and the furnace lid of the monocrystalline silicon growth furnace can be connected or disconnected. The mounting plate assembly can be used for conveniently and safely taking monocrystalline silicon at any time in the middle ...

Automatic combustion control method and automatic combustion control system for incinerator

The invention provides an automatic combustion control method and an automatic combustion control system for an incinerator. The automatic combustion control method includes controlling starting and stopping of a feeding grate and an incinerating grate on the basis of the temperature of a hearth or the flow of steam in the incinerator; controlling movement of the feeding grate and the incinerating grate on the basis of the flow of the steam in the incinerator and the internal infrared temperature of the incinerator; controlling the air volumes of various regions of a bottom of the incinerator on the basis of the content of oxygen in the incinerator. The automatic combustion control system comprises a grate control module, an air system control module and a combustor control module. The automatic combustion control method and the automatic combustion control system have the advantages that integral garbage feeding procedures and integral garbage combustion procedures can be automatically ...

Picture live transmission method and device in instant communication

The invention discloses a picture real-time transmission method of instant communication and a relative device, for resolving the problems of prior art which has bad picture clearness or can not see whole picture. The invention decodes picture at picture sender, codes picture via multiple resolutions, and transmits the picture via flow media and network to a picture receiver, the picture receiverreceives and decodes the picture, and displays the decoded picture to user, therefore, user can see clearer picture. The picture sender comprises a decoder, a coder, and a sender. The picture receiver comprises a receive unit, a buffer, a timer, a decoder, and a display unit.

Motion estimating method for video data compression

Wireless sensor network antenna characteristic test system

The utility model discloses a wireless sensor network antenna characteristic test system, including center test node and a plurality of terminal test node, characterized in that: center test node by the base, be fixed in aluminium pole on the base, set up in the antenna of aluminium peak of the staff end, order about aluminium pole pivoted step motor and first circuit part is constituteed, antenna on the center test node includes at least one omnidirectional antenna and a plurality of directional aerial, directional aerial on the node is tested according to main lobe direction evenly distributed in the center. The utility model discloses a wireless sensor network antenna characteristic test system can carry out the automatic measure to a plurality of antennas simultaneously, need not artificial intervention in single measuring period, and the test system is measured and is saved measured data the radio signal intensity by the test antenna according to the test method of design to be equipped ...

Half automatic weld assembly line of small -bore straight tube and sleeve pipe

The utility model relates to a half automatic weld assembly line of small -bore straight tube and sleeve pipe, it includes first bed -jig (1), second bed -jig (2), straight tube driving roller device (3), sleeve tube transmission roller device (5) and half automatic welder (6) its characterized in that, straight tube driving roller device (3) sets up between first bed -jig (1) and second bed -jig (2), sleeve tube transmission roller device (5) sets up in the place ahead of straight tube driving roller device (3), half automatic welder (6) set up in the place ahead of sleeve tube transmission roller device (5). The utility model discloses half automatic weld assembly line of small -bore straight tube and sleeve pipe has the overheadhoist of reduction frequency of utilization, improves production efficiency's advantage.

Thermal management system and vehicle

The invention belongs to the technical field of vehicle thermal management, and particularly relates to a thermal management system and a vehicle. The thermal management system comprises a first cooling device; the first cooling device comprises a first radiator, a first cooling pipeline provided with a first cooling assembly and a second cooling pipeline provided with a second cooling assembly. The first radiator comprises a first radiating body and a second radiating body; an outlet of the first heat dissipation body is communicated with an inlet of the second heat dissipation body, the heat management system comprises a first cooling loop and a second cooling loop, and in the first cooling loop, cooling liquid flows through the first heat dissipation body, the second heat dissipation body and the first cooling pipeline and then flows to the second cooling pipeline; in the second cooling loop, cooling liquid flows through the first heat dissipation body and then flows to the second cooling ...

Belt conveyor with deviation rectifying function and conveying belt deviation rectifying method

The invention discloses a belt conveyor with a deviation rectifying function and a conveying belt deviation rectifying method, and relates to the field of conveyors. The belt conveyor comprises a deviation rectifying support, a deviation rectifying mechanism, a carrier roller, a conveying belt, a plurality of deviation measuring mechanisms and an electric control mechanism; the deviation rectifying mechanism is installed on the deviation rectifying support and comprises a self-aligning swing frame, a rotating power assembly and a cross shaft assembly. The swing frame center of the self-aligning swing frame is connected to the deviation rectifying support through a cross shaft assembly, and the carrier roller is installed at the top of the self-aligning swing frame; the rotary power assembly is arranged below the aligning swing frame and is connected with the aligning swing frame; the deviation measuring mechanism is arranged on the side of the deviation correcting bracket or right above ...

Precursors for lithium transition metal oxide cathode materials for rechargeable batteries

Compounds that are ERK inhibitors

Disclosed are the ERK inhibitors of formula 1.0: and the pharmaceutically acceptable salts, esters and solvates thereof. Q is a piperidine or piperazine ring that can have a bridge or a fused ring. The piperidine ring can have a double bond in the ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.

Chemiluminescence Detector and Detection Method Thereof

The disclosure provides a chemiluminescence detector. The chemiluminescence detector includes a reagent storage device, configured to store a reagent; a reaction device, configured to support a plurality of support reaction containers and perform a sample adding operation, a reagent adding operation and an incubating operation, the reaction device including a reaction outer disc mechanism configured to support the reaction containers and perform the reagent adding operation and an uniform mixing operation and a reaction inner disc mechanism configured to support the reaction containers and perform the incubating operation; a reagent storage device, a separate injection device, a cleaning device and a measuring device are arranged around an outer periphery side of the reaction outer disc mechanism. In this way, the operations on the reaction outer disc mechanism and the reaction inner disc mechanism is able to be performed simultaneously and are not interfered, so the detection speed of ...

Intelligenter Ultraschallstapel und Verfahren zum Steuern eines Ultraschallsystems, das einen intelligenten Ultraschallstapel aufweist

Ein Ultraschallsystem hat einen Ultraschallstapel, der durch eine Stromversorgung angeregt wird. Der Ultraschallstapel hat eine Vielzahl von Komponenten, umfassend einen Ultraschallkonverter, einen Verstärker und eine Ultraschall-Sonotrode. Ein Verfahren zum Steuern des Ultraschallsystems mit der Stromversorgung umfasst, nachdem eine der Komponenten des Ultraschallstapels durch eine Ersatzkomponente ersetzt wurde, Eingeben eines Amplitudenparameters der Ersatzkomponente in die Stromversorgung, Bestimmen mit der Stromversorgung einer Amplitude eines AC-Anregersignals, bei welchem der Ultraschallkonverter anzuregen ist, basierend auf Amplitudenparametern der Komponenten umfassend die Amplitudenparameter jeder Ersatzkomponente. Die Stromversorgung setzt dann die Amplitude des AC-Anregersignals auf diese bestimmte Amplitude.

A performance-based representation for support of multiple decisions

Spiral tube detection probe propulsion apparatus

The invention belongs to the technical fields of spiral tubes and nondestructive detection propulsion apparatuses of heterotypic tubes thereof, and concretely relates to a spiral tube detection probe propulsion apparatus. The propulsion apparatus is composed of an air compressor, a reversing valve, a pushing and pulling device, a pneumatic propulsion device, a forward pulling conduit, a reverse pulling conduit, a probe and a cylinder, wherein the air compressor is connected with the reversing valve; the pneumatic propulsion device is used for storing a gas, and forward or backward pulls the probe when a preset critical pressure is reached; when the probe moves forward in a spiral tube, the air compressor inflates the pneumatic propulsion device to provide forward power, and when the preset critical pressure is reached, the probe is pushed to forward move, and a pinch roller and a probe disc synchronously rotate to uniform release the probe; and when the probe passes through the entire spiral ...

Chinese character scanning, recognising and inputting system

The invention relates to a computerized Chinese character scanning recognition input system. Said system uses the "soft thesaures " to integrate characters, words, sentences, self-defined phrases andprinting form and handwriting scanning recognition input measures into an organic whole, adopts the recognition processing method which not only can effectively use charater form structure characteristic information, but also can fully use syntactic information to make real-time processing of scanned data, and possesses very strong self-learning and self-adaptive capability, and can implement recognition processing of international 6763 characters (including regular script, Song typeface, imitation Song typeface, boldface type and various handwriting characters) and 682 non-character marks, and its recognition speed is more than 20 characters/sec. and scanning recognition correct rate is up to 85-99%.

Method for preparing Chinese medicine for treating hyperlipemia

The invention relates to a preparation method of a Chinese medicinal preparation for treating hyperlipidemia, and belongs to the technology field of Chinese medicine preparation methods. The currently used blood lipid reducing medicines for treating hyperlipidemia are easy to cause adverse reactions. For example, etofibrate may induce upper abdominal fullness, pruritus, and so on. The preparation is prepared from processed Cyperus rotundus, Aucklandia lappa, Lindera aggregata, Citrus reticulata, Citrus reticulata, Fructus Aurantii Immaturus, Magnolia officinalis, Fructus Amomi, Fructus Amomi Rotundus, Radix Et Rhizoma Nardostachyos, Cortex Citri, Salvia miltiorrhiza, Ligusticum chuanxiong, Semen Persicae, Carthamus tinctorius flower, Lycopus lucidus, Radix Curcumae, Curcuma longa, Corydalis yanhusuo, Trogopterus xanthipes dung, Olibanum, Myrrha, Dalbergia odorifera, Astragalus membranaceus, Atractylodes macrocephala, Rhizoma Polygonati, Gossypium herbaceum root, Herba Bidentis Tripartitae ...

Thermo-crosslinked product thin film of fluorine-containing polyolefin and preparation method thereof

The invention relates to a fluorine-containing polyolefin, a thermo-crosslinked product thin film of the fluorine-containing polyolefin and a preparation method thereof. The thermo-crosslinked product thin film is prepared through following steps: (1) chemically synthesizing the fluorine-containing polyolefin; (2) preparing a product through a coupling reaction between the fluorine-containing polyolefin and a Grignard reagent. The product can be firstly subjected to film building and then is used for forming the thermo-crosslinked product thin film of the fluorine-containing polyolefin, which is uniform in thickness, through crosslinking under a heating condition, wherein the thin film has following advantages: (1) the thin film has a high dielectric constant reaching about 4.2, which is higher than that of majority of linear polymer dielectric materials; (2) the thin film is low in dielectric loss being about 0.5%, which approximates that (0.018%) of biaxially oriented polypropylene; ( ...

Wireless monitoring management system

A wireless monitoring management system is provided. A PC client and a mobile phone client are connected with a terminal through a server. The terminal is connected with a sensor and peripheral equipment. The PC client and the mobile phone client receive alarm information sent by the terminal through a wireless network and transmit a control signal to the terminal. The wireless monitoring management system is an internet-of-thing terminal device which works based on a GSM/CDMA network, and receives messages or multimedia messages sent by the terminal through a mobile phone or a mail box so as to obtain on-site alarm information; the wireless monitoring management system is convenient to install, easy to operate, and strong in expansibility; the system is capable of carrying out remote monitoring through the mobile phone and a computer; the system supports various alarming ways, such as messages, multimedia messages, mails, and telephone calls and the like; and motion detection technology ...

Method and system for recommending network information

The invention provides a method and a system for recommending network information. The method comprises steps as follows: obtaining an attribute collection of network information within a designated time scale; performing an attribute value weighted approach on the attribute collection so as to obtain overall attribute value of the network information within the designated time scale; and recommending the network information with the overall attribute value not less than a designated attribute threshold value through a friend link. The method and system for recommending the network information can improve the precision in recommending the designated network information.

Underground disease object identification method based on neural network

The invention discloses an underground disease object identification method based on a neural network, and particularly relates to the technical field of the neural network, and the method comprises the following steps: carrying out the image collection of a ground disease, collecting the waveform image data of an underground disease through a radar, carrying out the matching of the waveform image of the ground disease and the waveform image of the underground disease, and carrying out the recognition of a target object. The method comprises the following steps: randomly selecting a part of samples as sample training data, calculating a reflection coefficient according to a formula, judging the existence of a void layer according to the reflection coefficient, calculating the depth of an underground reflector according to the formula, calculating the wave velocity of electromagnetic waves according to the formula, establishing an identification item of a disease body, and carrying out batch ...

Operating platform for welding outer frame steel column

The operating platform comprises a bottom frame, a handrail frame and a supporting plate, the middle of the bottom frame is provided with a column via hole for the outer frame steel column to penetrate through, the handrail frame is fixedly arranged at the edge position of the bottom frame in a surrounding mode, and the supporting plate is fixedly connected to the upper surface of the bottom frame. The bottom frame is fixedly connected with at least two first lifting lugs, the first lifting lugs are arranged close to the column via holes, and the first lifting lugs are detachably connected with the outer frame steel columns. The operation platform for welding the outer frame steel column is convenient to mount and dismount, the mounting time for mounting the operation platform and the outer frame steel column is shortened, the mounting risk is reduced, the mounting procedure is simplified, and vertical movement and repeated use of the operation platform are facilitated.

PRECURSOR FOR LITHIUM TRANSITION METAL OXIDE CATHODE MATERIAL FOR RECHARGEABLE BATTERY

The present invention discloses a microparticle precursor compound for preparing a lithium transition metal oxide powder which is for being used as a cathode active material in a lithium ion battery, the precursor having general formula, Ni_xMn_yCo_zA_aO_v(OH)_w, wherein 0.15 < v < 0.30, v+w = 2, 0.30 <= x <= 0.75, 0.10 <= y <= 0.40, and 0.10 <= z <= 0.40, A is a dopant satisfying a <= 0.05, x+y+z+a = 1, the precursor is formed of a crystal structure having an XRD pattern having a twin peak at 2θ = 38±0.5°, the twin peak includes a left peak having a peak intensity of I_L and a right peak having a peak intensity of I_R and has a peak intensity ratio R = I_R/I_L (R > 0.7), and the XRD pattern is an XRD pattern which is free from a peak belonging to a spinel, an oxyhydroxide compound or both thereof. COPYRIGHT KIPO 2018 ...

Measuring chamber, working method of measuring chamber, chemiluminescence measurement method of measuring chamber and chemiluminescence detector

The present disclosure relates to a measuring chamber, a working method of the measuring chamber, a chemiluminescence measurement method of the measuring chamber and a chemiluminescence detector. The measuring chamber includes a dark chamber, a first substrate nozzle, a photomultiplier detection component, a waste liquor adsorption needle component, a reaction cup turntable and a plurality of reaction cup processing stations; the reaction cup turntable is provided in the measuring chamber rotationally; and the plurality of reaction cup processing stations are sealed in a mutually light-isolated manner. When the instrument works, reaction cups in the reaction cup turntable are moved in the dark chamber; and after the reaction cups are moved to corresponding processing stations for processing the reaction cups, the plurality of different processing stations for processing, the reaction cups may simultaneously process the reaction cups moved to the corresponding reaction cup processing stations ...

Compounds that are ERK inhibitors

Disclosed are the ERK inhibitors of formula 1.0: and the pharmaceutically acceptable salts, and solvates thereof. Q is a tetrahydopyridinyl ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.

Compounds that are ERK inhibitors

Polycyclic indazole derivatives and their use as ERK inhibitors for the treatment of cancer

Method for preparing polypeptide by beer sediment

The invention discloses a method for preparing polypeptide by beer sediment. The method comprises the following steps: drying, pulverizing and sieving wet beer sediment to obtain beer sediment; adding extractant to the beer sediment and stirring the mixture at room temperature, filtering, deslagging and centrifuging the mixture to obtain protein extracting solution; adjusting pH value to 4.0-5.0 for precipitation; removing supernatant, carrying out vacuum freeze drying to obtain crude polypeptide; adding disodium hydrogen phosphate-citric acid buffer solution to the beer sediment crude protein, adjusting pH value of the mixture to 6.5-8.5; adding Alcalase alkaline protein enzyme, heating to 45-65 DEG C, carrying out hydrolysis for 1-5h while the mixture is stirred; afterwards killing enzyme in boiling water and centrifuging the mixture; taking centrifuged supernatant for gel column analysis and respectively collecting peaks and then carrying out concentration and freeze drying to obtain ...

Overflowing rain sewage on-site elimination stepped ecological sewage control structure

The invention discloses an overflowing rain sewage on-site elimination stepped ecological sewage control structure, which is a shore type structure and is provided with a cascade ecological treatment and purification system. In the overflowing rain sewage on-site elimination stepped ecological sewage control structure, connecting structures are built by using water permeable bricks in a certain proportion; and a water uniform distribution supporting layer, biological interception and absorption packing, biological filtering packing, a vegetable substrate layer and a triangular-notch weir are arranged between an overflowing rain sewage incoming place and an outgoing place. The structure of the invention overcome the drawbacks of large floor area, high medicament consumption and high energy cost and the like of the conventional overflowing rain sewage on-site treatment facilities. The structure of the invention is simple, low in construction cost, free from operating power and convenient ...

Control system and method for incinerator grate burn-out

The invention provides a control system and method for incinerator grate burn-out. The control system comprises a rubbish data detection module and a burn-out section control module, wherein the rubbish data detection module is used for detecting rubbish related data of an incinerator grate; the burn-out section control module is used for adjusting related parameters of a burn-out section of the incinerator grate on the basis of the rubbish related data so that the slag burning decrement rate can be minimized. By the adoption of the control system and method, control over minimization of the slag burning decrement rate can be achieved, and the labor intensity of an operator can be relieved.

Web page dynamic updating method, system and apparatus

The present invention relates to the communication field and provides a dynamic update method of web pages and a system and equipment. The method comprises following procedures: A. according to a request sent out by a client, a server processes stored paper data and feedbacks a message comprising a processing result; B. after the client receives the message, the client carries out corresponding operation on a node tree structure of the stored page data according to the processing result of page data by the server; C. according to the node tree structure, the client updates the local stored page data and uses the total updated page data to draw a web page to display on a user interface. The invention uses the node tree structure to store the requested page data through the client; when the page data is processed by the server, the node tree structure is used to update the local page data synchronously to ensure the consistency of data between the server and the client.

Colloidal gold test paper card for detecting enrofloxacin medicament residue

The invention provides a colloidal gold immunologic test paper card for detecting enrofloxacin drugs, comprising a reaction film, a sample pad, a conjugate releasing pad, a water absorbing pad and a back lining, wherein the reaction film is provided with a test zone coated with the enrofloxacin drugs, namely carrier protein conjugates and a quality control zone coated with sheep-anti-mouse IgG; and the conjugate releasing pad is coated with a monoclonal antibody of the enrofloxacin drugs, namely a colloidal gold label. The invention also provides a method for applying the test paper card to detect the enrofloxacin drugs, including the following steps of sample preliminary treatment, detection by using the test paper card and detected result analysis. The test paper card can be used for detecting the residual quantity of the enrofloxacin drugs in animal foods, such as pork, pork liver, chicken, chicken liver, serum, fishes and shrimps, has the advantages of simple operation, high sensitivity ...

System and method for information download of the embedded system device

The system in an embedded system to download data comprises: a download server storing data for different embedded system and providing WEB service, a communication device to connect former two devices and download/transfer data. Besides, there is a type identification unit for embedded system device, a format conversion unit to converse device data into corresponding format, and an ID unit.

Method for enhancement of raw water biological pretreatment biological membrane enrichment and operating performance stability

The invention provides a method for enhancement of raw water biological pretreatment biological membrane enrichment and operating performance stability. The method is characterized in that a raw water biological pretreatment process is started under the condition that inoculation of contaminated raw water is performed, an inner circulating operating mode of inflow of raw water is adopted and an appropriate amount of nutrient elements are added, at the same time, diatomite is added as an auxiliary carrier to form biological diatomite, and furthermore, functional microbes are retained, so as to enable the biological pretreatment process to be efficient and stable in operating performance. The method has the advantages that an inner circulating continuous water feeding mode is adopted, and a relatively stable biological pretreatment process start environment is provided, therefore, mixing of low-concentration nutrient medium is facilitated, and an appropriate hydrodynamic shear force is provided ...

Electrodeless radio frequency plasma bulb

The utility model discloses an electrodeless radio frequency plasma bulb, have closed cavity's foam in including, foam internal cavity both ends terminal surface sets up to the prominent structure in cavity inside, is provided with luminescent substance in the foam internal cavity, and it has noble gas still to fill in the foam internal cavity. The utility model discloses prolonged the life -span of bulb greatly, the grading efficiency of lamps and lanterns is very high to improve the luminous efficacy of whole lamps and lanterns greatly, can carry out reasonable regulation to color rendering index, light efficiency and colour temperature on a large scale, simple structure, small, power is big, and is with low costs, the mass production of being convenient for.

Water sale management system of internet of things

A water sale management system of an internet of things comprises a server set of at least one server, a disk array, a terminal supervisor, network POS (point-of-sale) machines, prepayment water meters and charging cards, wherein the disk array is used for storing information and the terminal supervisor is used for communicating with a center of a tap water company. The server set is communicated with the disk array and a firewall in both ways and connected with the terminal supervisor and the network POS machines distributed at various network points in via signals, the prepayment water meters serving as user terminal equipment are mounted on water mains in houses of users, and the charging cards correspond to the prepayment water meters one by one. The water sale management system has the advantages that automatic payment, visiting charging by swiping cards and multi-channel payment are realized, and an intelligentialized application level of the tap water company is improved.

Small automatic multi-stage oil-containing waste water treating device

The invention relates to an oil separating device for treating small-scale oil-containing waste water, in particular to a small automatic multi-stage oil-containing waste water treating device, which consists of a water inlet pipe, a fine screen, a granule removing area, a gravity oil-removing area, an oil collecting pipe, an absorption area, a PLC water level automatic control device, an oil-separating felt drawer, an activated-charcoal column and a drain pipe, wherein the water inlet pipe is arranged at the top end of the granule removing area; the fine screen is arranged between the granule removing area and the water inlet pipe and is slightly higher than the lowest water level; the granule removing area is communicated with the gravity oil-removing area; the oil collecting pipe and the PLC water level automatic control device are arranged at the upper end of the gravity oil-removing area, and the oil collecting pipe is as high as or slightly higher than the highest water level; the ...

Vehicle door limiter structure without gear limiting

The invention relates to the technical field of limiters, in particular to a gear-limiting-free vehicle door limiter structure which comprises a vehicle body and a vehicle door rotationally installed on the vehicle body and further comprises a limiting assembly. The limiting assembly comprises a support, a rotating arm, a fixed seat and a damping component, the support is fixedly connected with the vehicle body, the rotating arm is rotationally installed on the support, the damping component is arranged on the rotating arm, the fixed seat is fixedly connected with the vehicle door, and the fixed seat is connected with the rotating arm through the damping component. When the vehicle door is opened, the vehicle door drives the fixing base to move, damping is provided for movement of the fixing base through the damping component, then certain damping force needs to be overcome when the vehicle door is opened, the vehicle door can be parked at any angle through the damping force, and the requirement ...

Metal matrix graphene composite material and preparation method and application thereof

The invention discloses a metal matrix graphene composite material and a preparation method and application thereof. Graphene powder is subjected to electric explosion operation through an electric explosion method, generated graphene aerosol is directly released into a graphene aerosol chamber filled with argon, the graphene aerosol with the required concentration suspended in an argon medium is obtained, a circulating fan and a motor are started before the aerosol is agglomerated, and the graphene aerosol with the required concentration is agglomerated. The graphene aerosol is mixed with metal particle powder after passing through a filter screen, and interception capture, inertial deposition and diffusion deposition effects are generated in the mixing process, so that graphene is stably adsorbed on the surfaces of metal particles, and the metal matrix graphene composite material is obtained. The content of the graphene sheets uniformly dispersed on the metal matrix in the composite material ...

Method for assembling and adjusting device provided with array optical system

The invention relates to an installation and adjustment method for a device provided with an array optical system, belongs to the technical field of optical system device installation and adjustment methods, and solves the problem that the installation and adjustment process of an existing optical system device is complex. The invention discloses an assembling and adjusting method of a device provided with an array optical system. The device provided with the array optical system comprises the array optical system and an assembling frame suitable for the array optical system. The installation and adjustment method of the device provided with the array optical system comprises the following specific steps: S1, fixing the image rotation lens structural member on the supporting flange plate; s2, one end of a connecting supporting rod is fixedly connected with the supporting flange plate; s3, the other end of the connecting support rod is in contact connection with the imaging primary mirror ...

Compounds that are ERK inhibitors

Photocatalytic film distillation printing and dyeing wastewater treatment and recovery system and technology

The invention discloses a photocatalytic film distillation printing and dyeing wastewater treatment and recovery system and technology. The treatment and recovery technology comprises the following steps: putting printing and dyeing wastewater into an aeration zone of a photocatalytic degradation reaction tank for aeration, and conducting electrodeless ultraviolet catalytic reaction on the aerated wastewater I; after reaction, pumping wastewater into a film distillation biological reaction tank for aeration, conducting desalination on the aerated wastewater II through a distillation film component, carrying out circulating cooling, repeated aeration and desalination through a first circulating pump and a condenser, and discharging qualified water through a clean water basin. The system and the technology have the advantages that the COD removing rate for wastewater reaches 99% or higher, the decolourization ratio and the desalination rate reach 99 percent or higher, highly purification ...

Vacuum testing protector

The invention relates to the technical field of single crystal furnace testing equipment and aims at providing a vacuum testing protector. The vacuum testing protector comprises a touch switch and a metal corrugated tube, wherein the touch switch is connected with an open circuit control circuit or a controller of a single crystal furnace; one side of the metal corrugated tube is arranged in a pressure testing opening of an auxiliary vacuum system; the auxiliary vacuum system is communicated with a furnace chamber of the single crystal furnace; the other side of the metal corrugated tube is contacted and communicated with the tough switch; the following conditions can be guaranteed: when the pressure in the single crystal furnace is in a normal state, the end surface of the metal corrugated tube contacts with the touch switch to trigger the touch switch; when the pressure in the single crystal furnace is in a negative pressure state, the metal corrugated tube is compressed, so that the ...

Hand terminal system

A hand terminal system comprises development unit utilizing cross-platform language to develop application program used in hand terminal and hand terminal utilizing virtual machine to interpret said application program to be code being able to be executed by machine for realizing preset function of said application program.

Supply circuit of telephone expenses payment mechanism

The utility model discloses a supply circuit of telephone expenses payment mechanism, including the tertiary filtering structure of series connection, first order filtering structure includes first inductance and first electric capacity, and second level filtering structure includes that triode, first fortune are put puts with second fortune, and third level filtering structure includes third electric capacity and fourth electric capacity. The utility model discloses the not enough of prior art can be improved, circuit structure has been simplified.

Wing wallboard fatigue test spare

The utility model discloses a wing wallboard fatigue test spare belongs to the experimental field of aircraft fatigue strength. Including examination section (1), changeover portion (2) and centre gripping section (3), centre gripping section (3) is connected through changeover portion (2) respectively in the both ends of examination section (1), the thickness of changeover portion (2) is from the orientation chamfered thickened of examination section (1) to centre gripping section (3) extension, (1) the central trompil of examination section forms examination district (11), trompil between the examination district (11) and changeover portion (2) forms both ends depressed area (12), and examination section (1) both sides are inwards sunken, form both sides depressed area (13). The utility model discloses the mode that fatigue test spare adopted smooth transition of fillet and the even chamfered transitional face of thickness to combine has avoided the testpieces to destroy in advance in ...

Situation switching detection method and its detection system

Being suitable to image process domain, the invention discloses method and system for detecting scene switch. The method includes following steps: (1) carrying out motion estimation for previous frame and current frame, filtering out candidate frames for scene switch; (2) carrying out comparison of histogram between previous frame and candidate frames of current scene switch, and filtering out the scene switch frame from candidate frames of scene switch. Using filtering detection in two stages based on motion estimation and comparison of histogram. The invention through combined measurement of degree of similarity carries out determinant degree of similarity of images. The invention raises reliability for detecting scene switch, and efficiency of compressing codes, reduces misjudgment, soas to reach requirement on video transmission under low bit rate.

Membrane electric capacity deionization system

The utility model provides a membrane electric capacity deionization system, include: water installations for introduce the demineralizer with stoste, the demineralizer for carry out desalination to stoste, water -collection device is including valve and header tank, monitoring device for the conductivity and the control business turn over water of monitoring water carry out desalination and regenerative process, including conductivity meter and the control unit. The demineralizer comprises box and the at least a set of electrode unit of placing in the box, is equipped with water inlet, a topat the bottom half and is equipped with at least one delivery port, and the electrode unit is from top to bottom personally experienced sth. Part of the body for the mass flow body, activated carbon fiber electrode, cloudy cation exchange membrane, insulating diaphragm, cloudy cation exchange membrane, activated carbon fiber electrode and mass flow in proper order. This membrane electric capacitydeionization ...

Infrared temperature measuring device for high-strength microwave high-humidity environment

The invention provides an infrared temperature measuring device for a high-strength microwave high-humidity environment. The infrared temperature measuring device comprises an infrared temperature measuring thermal imager, a metal sleeve, a gas conveying pipeline and a gas generating device, the infrared temperature measurement thermal imager and the gas conveying pipeline are both arranged in the metal sleeve; a first end of the gas conveying pipeline faces a lens of the infrared temperature measurement thermal imager, and a second end of the gas conveying pipeline is connected with the gas generating device; the gas generation device is used for generating dry gas, and the dry gas is transmitted to a lens of the infrared temperature measurement thermal imager through the gas transmission pipeline. The technical problem that an infrared temperature measuring device in the prior art cannot work normally in a high-strength microwave high-humidity extreme environment can be solved.

Crystal protection device and crystal girdling equipment

The invention provides a crystal protection device and crystal girdling equipment, belongs to the technical field of crystal girdling processing, and solves the problem of low crystal edge skin fixing efficiency in the prior art. The clamping device comprises a mounting disc and at least two clamping mechanisms, and the clamping mechanisms are circumferentially distributed on the mounting disc and connected with the mounting disc so as to jointly clamp the outer circle of a to-be-clamped piece. Wherein the clamping mechanism can stretch out and draw back in the thickness direction of the to-be-clamped piece, the clamping mechanism is provided with a clamping station on the stretching-out and drawing-back path, and the clamping station can be dynamically adjusted relative to the movement of the to-be-clamped piece. According to the crystal protection device, the resin plate outer circle/crystal edge skin can be fixed while girdling is conducted, the process of manual gluing and fixing is ...

TCP bypass interdiction method and device

A TCP bypass interdiction method and device are provided. The method comprises: a DPI device between a client terminal and a service terminal acquiring a MSS negotiation value on the basis of a TCP handshake packet; when a suspicious packet is monitored, the DIP device constructing an RST packet according to the suspicious packet and the MSS negotiation value. The RST packet comprises a source direction RST packet and target direction RST packets. The receiving terminal of the source direction RST packet is the same with the transmitting terminal of the suspicious packet. The receiving terminals of the target direction RST packets are the same with the receiving terminal of the suspicious packet. SEQ values of the target direction RST packets are sequentially increased by at least one MSS negotiation value. The method comprises the DPI device transmitting the RST packet to the client terminal and the service terminal respectively.

Measuring Chamber, Working Method of Measuring Chamber, Chemiluminescence Measurement Method of Measuring Chamber and Chemiluminescence Detector

The present disclosure relates to a measuring chamber, a working method of the measuring chamber, a chemiluminescence measurement method of the measuring chamber and a chemiluminescence detector. The measuring chamber includes a dark chamber, a first substrate nozzle, a photomultiplier detection component, a waste liquor adsorption needle component, a reaction cup turntable and a plurality of reaction cup processing stations; the reaction cup turntable is provided in the measuring chamber rotationally; and the plurality of reaction cup processing stations are sealed in a mutually light-isolated manner. When the instrument works, reaction cups in the reaction cup turntable are moved in the dark chamber; and after the reaction cups are moved to corresponding processing stations for processing the reaction cups, the plurality of different processing stations for processing, the reaction cups may simultaneously process the reaction cups moved to the corresponding reaction cup processing stations ...

Dust suppressing and removing device for fully mechanized coal mining face

The invention discloses a dust suppressing and removing device for a fully mechanized coal mining face. The technical thought of performing dust prevention and control from the source is adopted; a group of air curtain nozzles for jetting air current is arranged behind two cutting parts of a coal mining machine and close to a control part of the coal mining machine respectively, thereby forming air walls wrapping fog fields formed by spray dedusting equipment inside and outside the coal mining machine respectively on two drums of the coal mining machine; a bracket spray dedusting device and a bracket dust absorbing and purifying device are arranged on each bracket respectively in order to effectively precipitate or absorb a large amount of dust falling from both sides and the front of the brackets and dust overflowing from a control-dedusting system of the coal mining machine in a precipitating or absorbing bracket-moving process. Compared with the prior art, the dust suppressing and removing ...

Pneumatic signal device

The utility model relates to a signal field specifically is a pneumatic signal device in the pit, including two sets of above the same signal liaison organizations of structure, every group signal liaison organization includes that one end communicates the inflator on air supply in the pit, the flexible slip in inside piston and the spring stationary blade of inflator, be fixed in spring stationary blade one side and support the reset spring of tight fit with the piston, be fixed in the catch bar that spring stationary blade opposite side just stretches out another terminal surface of inflator, be fixed in the hammer that strikes of catch bar tip, and with strike the hammer matched with bell body, it has the exhaust hole to be located to open on the inflator between piston and the spring stationary blade, install the control switch of control air supply on the air inlet of inflator, the inflator air inlet department of every group signal liaison organization is linked together through the ...

Changeable surge damping valve of cracking pressure

The utility model discloses a changeable surge damping valve of cracking pressure, including the work end housing body, the pressure source end housing body, sealing rubber circle, core bar, inclined plane rubber buffer, relief valve and gas cylinder. The work end housing body links firmly with the pressure source end housing body, and the other end of the pressure source end housing body links firmly with the relief valve, and the relief valve links firmly with the gas cylinder, and the core bar is located the internal one end of pressure source end housing and is equipped with the sealing rubber circle, and the core bar setting is equipped with the inclined plane rubber buffer in the internal one end of work end housing. The principle that adopts utilizes the external pressure that safe valve plug stem receives to equal interior pressure, and pressure is born in the deformation of certain component of this kind of relief valve independence, does not have the problem of metal fatigue, ...

Reaction cup loading device and full-automatic chemiluminescence immunoassay device

The invention discloses a reaction cup loading device and a full-automatic chemiluminescence immunoassay device. The reaction cup loading device comprises a transmission mechanism and a push mechanism, wherein the transmission mechanism comprises a bottom plate and a first horizontal transmission mechanism on the bottom plate; the push mechanism comprises a bracket component, a second horizontal transmission mechanism on the bracket component, a push rod connected with the second horizontal transmission mechanism and a guide control module; the guide control module comprises an initial end at a cup-push trip destination of the push rod, a terminating end at a cup-push trip starting point of the push rod, and a return rail which is arranged between the initial end and the terminating end and bypasses a cup-push trip; the distance between the initial end and the terminating end is more than a cup position and less than two cup positions. By the reaction cup loading device and the full-automatic ...

Port operation and production management system

A port operation and production management system includes a basic data management system, a production management system and a statistical query system, and all systems are connected through a network with a port production and operation management platform. According to the port operation and production management system of the invention, the system is used to realize comprehensive information management of production in a port, and to provide an efficient, standard, and scalable information platform for enterprise information management; a structure of the system uses a platform with a universal standard, advanced development technology and scalable data interface, so as to highlight the usability and versatility while ensuring safety; the scalability and stability of the system is taken full consideration into; the production efficiency of the port production management is improved; and a lot of labor cost is saved.

Process special for cutting steel pipe column profile and machining equipment

The invention discloses a special process method and processing equipment for cutting a profile in an assembly process during manufacturing of a steel pipe column of a residential steel structure. The special process method and the processing equipment comprise cutting objects and forms, means and equipment, processes and processes, basic process parameters and the like. According to the cutting object and form, required grooves, holes, marking lines or characters are sequentially cut or marked on the steel pipe column profile body according to the component deepening design machining drawing; cutting means and equipment adopt a plasma cutting torch, a power supply of the plasma cutting torch, a robot and a matched mechanism; the cutting process is completed through reasonable and efficient cutting procedures, technological parameters and program control. The special process method, the equipment frame and the function which are high in pertinence are provided for cutting machining of a ...

Goods shelf with high pressure resistance and lifting function

The invention relates to the technical field of goods shelves, and discloses a goods shelf high in pressure resistance and having a lifting function, the goods shelf comprises a bottom shell, a transmission mechanism is arranged in the bottom shell, and the top of the bottom shell communicates with four stand columns distributed in a rectangular array; the interiors of the four stand columns are rotationally connected with lead screws, one ends of the lead screws extend into the bottom shell, the bottoms of the four lead screws are fixedly connected with double-belt wheels, and belts are in transmission connection among the four double-belt wheels. The goods shelf with the high pressure resistance and the lifting function has the advantages of being convenient to use and the like, and solves the problems that most of existing goods shelves are formed by mutually fixedly connecting and assembling stand columns, cross beams and shelf plates, articles are placed on the shelf plates, and due ...

Intelligent micro-grid experiment system

The invention discloses an intelligent micro-grid experiment system. Comprising a computer, an RSCAD software platform, a central controller, an RTDS system, a wind power generation unit, a VME controller, a DC chopper I, a single-phase grid-connected inverter I, a photovoltaic power generation unit, a DC chopper II, a single-phase grid-connected inverter II, an energy storage battery, an energy storage converter, a load, a communication control node I, a communication control node II, a communication control node III and a micro-grid node system. The invention discloses a load unit and a micro-grid energy management system. The system has the advantages that an EtherCAT communication mode is used for communicating with a computer, compared with an existing micro-grid communication technology, an EtherCAT bus has great advantages in the aspects of topological flexibility, linear structure, construction cost, cycle time and the like, and the real-time performance and reliability of micro-grid ...

CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS

Chemical entities which are triterpenoid derivatives, pharmaceutical compositions and methods of treatment of inflammatory, neurodegenerative, neoplastic and autoimmune diseases are described. 2. At least one chemical entity of wherein Ris chosen from hydrogen and optionally substituted alkyl.3. At least one chemical entity of wherein Ris chosen from hydrogen and lower alkyl.4. At least one chemical entity of wherein Ris chosen from optionally substituted acyl.5. At least one chemical entity of wherein Ris chosen from —COCHand —COCHCH.6. At least one chemical entity of wherein Ris chosen from —P(—O)(OR)(OR) claim 1 , and —C(R)(R)OP(—O)(OR)(OR) claim 1 , where R claim 1 , R claim 1 , R claim 1 , and Rare independently chosen from hydrogen claim 1 , optionally substituted alkyl claim 1 , optionally substituted cycloalkyl claim 1 , optionally substituted heterocycloalkyl.7. At least one chemical entity of wherein Ris chosen from —POH.8. At least one chemical entity of wherein Ris chosen from —CHOPOH.9. At least one chemical entity of wherein Ris chosen from optionally substituted aminocarbonyl.10. At least one chemical entity of wherein Ris chosen from —CONHand —CONHCH.11. At least one chemical entity of wherein Ris chosen from optionally substituted acyl and optionally substituted lower alkyl.12. At least one chemical entity of wherein Ris chosen from hydrogen and optionally substituted lower alkyl.13. At least one chemical entity of wherein Ris chosen from optionally substituted aminocarbonyl.14. At least one chemical entity of wherein Ris chosen from optionally substituted alkoxycarbonyl.15. At least one chemical entity of wherein Ris chosen from optionally substituted sulfonyl.16. At least one chemical entity of wherein Ris chosen from hydrogen and optionally substituted lower alkyl.17. At least one chemical entity of wherein Rand Rare joined together with any intervening atoms to form an optionally substituted 5- to 8-membered heterocycloalkyl ring.19. A ...

COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR

Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases. 5. The method of in which the compound is administered orally.6. The method of in which the compound is formulated into a tablet.7. The method of in which the compound has a 5-substituent selected from 4-chlorophenyl or chloro.8. The method of in which the compound has a 6-substituent selected from fluoro or hydrogen.9. The method of in which the 3-substituent is a propane-1-sulfonamido group.10. The method of in which the compound is administered at a dose ranging from about 0.01 and 50 mg/kg.11. The method of in which the compound is administered at a dose ranging from about 0.1 and 20 mg/kg.12. The method of in which the compound is administered in multiple doses. This application is a continuation of U.S. application Ser. No. 12/906,980 filed Oct. 18, 2010, which is a divisional of U.S. application Ser. No. 11/473,347 filed Jun. 21, 2006, now issued as U.S. Pat. No. 7,836,288, which claims the benefit under 35 U.S.C. §119(e) of U.S. Provisional Application No. 60/692,960, filed Jun. 22, 2005, and U.S. Provisional Application No. 60/731,528, filed Oct. 28, 2005, which are incorporated herein by reference in their entireties and for all purposes.The present invention relates to kinases and compounds which modulate kinases, and uses therefor. Particular embodiments contemplate disease indications which are amenable to treatment by modulation of kinase activity by the compounds of the present invention.The information provided herein is intended solely to assist the understanding of the reader. None of the information provided nor references cited is admitted to be prior art to the present invention. Each of the references cited herein is incorporated in its entirety.Receptor protein kinases regulate key signal transduction cascades that control or are involved in the control of a ...

Inhibitors of Polo-Like Kinase

The present invention provides compounds having a structure according to Formula (I): 2. The compound of claim 1 , wherein A is a member selected from pyrrolidinyl claim 1 , piperidinyl claim 1 , morpholinyl claim 1 , thiomorpholinyl claim 1 , N-alkyl-piperazinyl claim 1 , oxazolidinyl claim 1 , thiazolidinyl claim 1 , pyridyl claim 1 , pyrimidinyl claim 1 , pyridazinyl claim 1 , pyrazinyl claim 1 , triazinyl claim 1 , pyrrolyl claim 1 , imidazolyl claim 1 , pyrazolyl claim 1 , thiazolyl claim 1 , isothiazolyl claim 1 , oxazolyl claim 1 , isoxazolyl claim 1 , thiadiazolyl claim 1 , triazolyl and tetrazolyl claim 1 , wherein A is substituted or unsubstituted.3. The compound of claim 2 , wherein A is a substituted or unsubstituted ring selected from the group consisting of pyridyl claim 2 , pyrazolyl and imidazolyl.4. The compound of claim 3 , wherein A is a substituted or unsubstituted ring selected from the group consisting of pyridin-3-yl claim 3 , pyridin-4-yl claim 3 , pyrazol-4-yl and imidazol-1-yl.9. A pharmaceutical composition comprising a compound according to and a pharmaceutically acceptable carrier.10. A method of treating a neurodegenerative disease comprising administering to a mammalian subject in need thereof a pharmaceutically effective amount of a compound according to or a composition according to .11. The method of claim 10 , wherein the disease is an alpha-synucleinopathy.12. The method of claim 11 , wherein the disease is a member selected from the group consisting of Parkinson's disease claim 11 , Parkinson disease with dementia claim 11 , PD at risk syndrome claim 11 , dementia with Lewy bodies claim 11 , diffuse Lewy body disease claim 11 , Lewy body dementia claim 11 , cortical Lewy body disease claim 11 , senile dementia of Lewy type claim 11 , Lewy body variant of Alzheimer's disease claim 11 , diffuse Lewy body type of Alzheimer's disease claim 11 , combined Parkinson's disease and Alzheimer's disease claim 11 , multiple system atrophy ...

PROTEIN HYDROLYSATE, POLYPEPTIDE SOLUTION AND POLYPEPTIDE, PREPARATION METHOD AND USE THEREOF

The present invention provides methods for the preparation of protein hydrolysate, peptide solution and peptide from BSG. The wet BSG or BSG powder is dispersed in extract solution to prepare the crude BSG protein or the crude BSG protein solution. Preparing the crude BSG protein solution using the crude BSG protein and adjusting the pH to 6.5˜8.5, or adjusting the pH of the crude BSG protein solution to 6.5˜8.5. Then the solution is hydrolyzed with protease at 45° C. to 65° C. for 1 h to 5 h in a water bath shaker to prepare BSG protein hydrolysate. The protein hydrolysate is heated to inactivate the protease and centrifuged to obtain the peptide solution. The peptide solution is separated by gel filtration and each peak is collected and pooled together to obtain the peptide. The protein hydrolysate, peptide solution and peptide in the present invention are all prepared from BSG which is a natural product and available at low cost throughout the year. There is no harmful material used in the production process. The results of in vitro experiment suggest that BSG peptide prepared by this method shows a significantly hypoglycemic effect. 1. A method for the preparation of a peptide solution from BSG , which comprises the following steps:(1) the wet BSG or BSG powder is dispersed in extract solution to prepare crude BSG protein or crude BSG protein solution;(2) preparing the crude BSG protein solution by the crude BSG protein prepared in step (1) into and adjusting the pH to 6.5˜8.5, or adjusting the pH of the crude BSG protein solution prepared in step (1) to 6.5˜8.5., then the solution is hydrolyzed with protease at 45° C. to 65° C. for 1 h to 5 h in a water bath shaker to prepare BSG protein hydrolysate; and(3) inactivating the proteases in the BSG protein hydrolysate prepared in step (2), then centrifugate the hydrolysate to obtain the peptide solution.2. The method according to claim 1 , wherein the crude BSG protein solution described in step (2) is prepared by ...

METHOD, SYSTEM AND SERVER FOR MANAGING FRIENDS' FEED IN NETWORK

Embodiments of the present invention provide a method, system and server for managing the friends' feeds in the network. Specifically, the method includes: receiving a friends' feeds viewing instruction; obtaining friends' feeds corresponding to a viewing user identity comprised in the friends' feeds viewing instruction, and determining friend intimacy degrees corresponding to the viewing user identity; sorting the obtained friends' feeds according to the friend intimacy degrees and one or multiple update properties comprised in the obtained friends' feeds, and outputting the sorted friends' feeds. It can be seen that the scheme provided by embodiments of the present invention can satisfy the requirements that the user pay different attentions to different friends. 1. A method for managing friends' feeds in a network , comprising:receiving a friends' feeds viewing instruction;obtaining friends' feeds corresponding to a viewing user identity comprised in the friends' feeds viewing instruction, and determining friend intimacy degrees corresponding to the viewing user identity;sorting the obtained friends' feeds according to the friend intimacy degrees and one or multiple update properties comprised in the obtained friends' feeds, and outputting the sorted friends' feeds.2. The method of claim 1 , wherein sorting the obtained friends' feeds according to the friend intimacy degrees and one or multiple update properties comprised in the obtained friends' feeds comprises:weighting a property value of the one or multiple update properties comprised in the obtained friends' feeds, and sorting the friends' feeds according to the friend intimacy degrees and weighted property value.3. The method of claim 1 , wherein determining the friend intimacy degrees corresponding to the viewing user identity comprises:obtaining interaction information of corresponding friends from a friends circle database according to the viewing user identity;computing a friend intimacy degree ...

CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS

Chemical entities that are arctigenin derivatives, pharmaceutical compositions and methods of treatment of cancer are described. 2. At least one chemical entity of wherein Ris chosen from hydrogen claim 1 , optionally substituted alkyl claim 1 , optionally substituted cycloalkyl claim 1 , and optionally substituted heterocycloalkyl.3. At least one chemical entity of wherein Ris chosen from optionally substituted alkyl claim 1 , optionally substituted cycloalkyl claim 1 , and optionally substituted heterocycloalkyl.4. At least one chemical entity of wherein Rand Rare independently chosen from optionally substituted alkyl.5. At least one chemical entity of wherein Rand Rare joined together to form an optionally substituted 4- to 8-membered heterocycloalkyl ring.6. At least one chemical entity chosen from4-(((3R,4R)-4-(3,4-dimethoxybenzyl)-2-oxotetrahydrofuran-3-yl)methyl)-2-methoxyphenyl dimethylcarbamate,4-(((3R,4R)-4-(3,4-dimethoxybenzyl)-2-oxotetrahydrofuran-3-yl)methyl)-2-methoxyphenyl piperidine-1-carboxylate,4-(((3R,4R)-4-(3,4-dimethoxybenzyl)-2-oxotetrahydrofuran-3-yl)methyl)-2-methoxyphenyl morpholine-4-carboxylate,4-(((3R,4R)-4-(3,4-dimethoxybenzyl)-2-oxotetrahydrofuran-3-yl)methyl)-2-methoxyphenyl piperazine-1-carboxylate,4-(((3R,4R)-4-(3,4-dimethoxybenzyl)-2-oxotetrahydrofuran-3-yl)methyl)-2-methoxyphenyl pyrrolidine-1-carboxylate,4-(((3R,4R)-4-(3,4-dimethoxybenzyl)-2-oxotetrahydrofuran-3-yl)methyl)-2-methoxyphenyl (2-hydroxyethyl)(methyl)carbamate,(S)-4-(((3R,4R)-4-(3,4-dimethoxybenzyl)-2-oxotetrahydrofuran-3-yl)methyl)-2-methoxyphenyl 3-hydroxypyrrolidine-1-carboxylate,(S)-4-(((3R,4R)-4-(3,4-dimethoxybenzyl)-2-oxotetrahydrofuran-3-yl)methyl)-2-methoxyphenyl 3-aminopyrrolidine-1-carboxylate,4-(((3R,4R)-4-(3,4-dimethoxybenzyl)-2-oxotetrahydrofuran-3-yl)methyl)-2-methoxyphenyl (2-methoxyethyl)(methyl)carbamate,(R)-4-(((3R,4R)-4-(3,4-dimethoxybenzyl)-2-oxotetrahydrofuran-3-yl)methyl)-2-methoxyphenyl 3-hydroxypyrrolidine-1-carboxylate,4-(((3R,4R)-4-(3,4- ...

Certain Chemical Entities, Compositions, and Methods

Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of using these chemical entities, e.g., for treatment of cancer are described. 1. The compound or pharmaceutically acceptable salt of claim 18 ,{'sub': 10', '7', '8', '6, 'provided that when Ris fluoro, then Ris not hydrogen, or Ris not hydrogen, or Ris not hydrogen, lower alkyl or halo.'}2. The compound or pharmaceutically acceptable salt of claim 1 , wherein Ris hydrogen claim 1 , cyano claim 1 , halo claim 1 , hydroxy claim 1 , carboxy claim 1 , optionally substituted alkoxy claim 1 , optionally substituted aryloxy claim 1 , optionally substituted alkoxycarbonyl claim 1 , optionally substituted alkyl claim 1 , optionally substituted aryloxy claim 1 , optionally substituted aryl claim 1 , optionally substituted heteroaryl claim 1 , optionally substituted heterocycloalkyl claim 1 , optionally substituted amino claim 1 , optionally substituted acyl claim 1 , optionally substituted alkoxycarbonyl claim 1 , optionally substituted aminocarbonyl claim 1 , optionally substituted aminosulfonyl claim 1 , optionally substituted carbamimidoyl claim 1 , or optionally substituted alkynyl.3. The compound or pharmaceutically acceptable salt of claim 2 , wherein Ris hydrogen claim 2 , cyano claim 2 , optionally substituted alkoxy claim 2 , optionally substituted aryloxy claim 2 , optionally substituted amino claim 2 , optionally substituted alkyl claim 2 , optionally substituted aryl claim 2 , optionally substituted heterocycloalkyl claim 2 , or optionally substituted heteroaryl.4. The compound or pharmaceutically acceptable salt of claim 3 , wherein Ris optionally substituted aryl claim 3 , optionally substituted heterocycloalkyl claim 3 , or optionally substituted heteroaryl.5. The compound or pharmaceutically acceptable salt of claim 4 , wherein Ris optionally substituted morpholinyl claim 4 , optionally substituted piperazinyl claim 4 , optionally substituted imidazolyl claim 4 , optionally ...

NOVEL HETEROCYCLIC COMPOUNDS AS ERK INHBITORS

The present invention provides a compound of the Formula I: (Formular I should be inserted here) or a pharmaceutically acceptable salt, solvate or ester thereof, wherein R, R1, R2 and R3 are as defined herein. The compounds are ERK inhibitors. Also disclosed are pharmaceutical compositions comprising the above compounds and methods of treating cancer using the same. 2. The compound of claim 1 , wherein R is H.4. The compound of wherein Ris selected from the group consisting of: phenyl claim 1 , pyridyl claim 1 , methylpyridyl claim 1 , methylindazolyl claim 1 , methylbenzothiazolyl claim 1 , pyridazinyl claim 1 , dihydropyran claim 1 , dioxidodihydrothiopyran claim 1 , dioxidotetrahydrothiopyran claim 1 , imidazolyl claim 1 , teterahydropyran claim 1 , benzofuranyl claim 1 , indazolyl claim 1 , pyridazinyl claim 1 , indazolyl claim 1 , imidazopyridly claim 1 , benzooxazolyl claim 1 , benzothiadiazolyl claim 1 , benzooxadiazolyl claim 1 , benzothiazolyl claim 1 , pyridine-one claim 1 , triazolopyridinyl claim 1 , dihydrobenzoimidazolyl claim 1 , benzohydrofuranyl; and wherein said Ris optionally substituted with 1 or more substitutents independently selected from the group consisting of: ═O claim 1 , —OH claim 1 , alkyl claim 1 , cycloalkyl claim 1 , haloalkyl claim 1 , alkoxy claim 1 , halo claim 1 , —NH—C(═O)-alkyl claim 1 , —S(═O)—N(alkyl)—C(═O)-alkyl claim 1 , cyano claim 1 , —S(═O)-alkyl claim 1 , —NH claim 1 , and —OC(═O)alkyl.5. The compound of claim 1 , wherein said Ris alkyl claim 1 , which is unsubstituted or substituted with at least one aryl.7. The compound of claim 6 , wherein:(a) n is 1; or(b) n is 1 and m is 0, 1 or 2; or{'sup': 3', '3', '3, 'sub': 3', '3, '(c) n is 1, m is 1 or 2, and Ris selected from the group consisting of halo, haloalkyl, —OSi(alkyl), hydroxyl, alkyl, cycloalkyl, alkoxy, aryl, —C(═O)OH, —C(═O)—O-alkyl, —C(═O)N(alkyl), —C(═O)NH-alkyl; or wherein two Rgroups together with the carbon atom to which both Rgroups are attached form —C(═O ...

Deburring machine

A deburring machine for removing burrs from workpieces includes a framework, a deburring mechanism and a transport mechanism. The deburring mechanism mounted on the framework, includes deburring units positioned on the framework. The transport mechanism is positioned on the framework adjacent to the deburring units. The transport mechanism includes a base, multi-station rotating plate and a first driver. The base is positioned on the framework. The multi-station rotating plate is rotatably positioned on the base. The first driver is positioned on the framework and connects with the base. The first driver is capable of driving the multi-station rotating plate to transport the workpieces to the plurality of deburring units, the plurality of deburring units are capable of removing the burrs of the workpieces.

METHOD AND SYSTEM FOR DISPLAYING ACTIVITIES OF FRIENDS AND COMPUTER STORAGE MEDIUM THEREFOR

Method and system for displaying activities of friends. The method includes, generating activity information from the activities of friends according to the friend relationship chain; classifying the activity information according to the preset classification rule to obtain the corresponding classification collection; acquiring the screening condition, extracting activity information that meets the screening condition from the classification collection, and displaying the activity information extracted. According to the method and system, through the classification and screening of activity information, the activities of friends which meet screening conditions entered by a user can be obtained and displayed. Using this method and the system, a large amount of information can be quickly screened and all the friends' effective activities can be provided to the user allowing user to achieve personalized browsing. 1. A method for displaying activities of friends , comprisinggenerating activity information from the activities of friends according to a friend relationship chain;classifying the activity information according to a preset classification rule to obtain a corresponding classification collection; andacquiring a screening condition to extract activity information that meets the screening condition from the classification collection, and displaying the activity information extracted.2. The method of claim 1 , wherein the classifying of the activity information according to the preset classification rule to obtain the corresponding classification collection comprises:extracting an attribute associated with the classification rule from the activity information, according to the preset classification rule; andclassifying the activity information according to the attributes to form the classification collection.3. The method of claim 2 , wherein the classification rule comprises at least one of an information attribute claim 2 , a friend attribute claim 2 , and a ...

INFORMATION PROVIDING METHOD AND SYSTEM

Embodiments of the present invention disclose an information providing method and system. The method includes: receiving data collected through a control module; collecting a user identification and operation information corresponding to the user identification in the data; associating and storing the user identification and the operation information corresponding to the user identification; and providing information for a user according to operation information corresponding to user identifications on a social relationship chain of the user. The system includes an interface module, a collecting module, a storing module and an information providing module. By the embodiments, the information related to the operation information of contacts is provided for the user. Since the social relationship chain is utilized, the possibility that the user is interested in the information related to the operation information of contacts is greater, and thus targeted information may be provided for the user. 1. An information providing method , comprising:receiving data collected through a control module;collecting a user identification and operation information corresponding to the user identification in the data;associating and storing the user identification and the operation information corresponding to the user identification; andproviding information for a user according to operation information corresponding to user identifications on a social relationship chain of the user.2. The information providing method of claim 1 , before storing the user identification and the operation information corresponding to the user identification claim 1 , further comprising: processing the user identification and the operation information corresponding to the user identification claim 1 , wherein the processing comprises at least one of:filtering out operation information based on a predefined condition, sorting the operation information, and classifying the operation information.3. The ...

INDAZOLE DERIVATIVES USEFUL AS ERK INHIBITORS

The present invention provides a compound of the Formula I: Formula I or a pharmaceutically acceptable salt, solvate or ester thereof, wherein R, R1, R2, R3, R4, X, m and n are as defined herein. The compounds are ERK inhibitors. Also disclosed are pharmaceutical compositions comprising the above compounds and methods of treating cancer using the same. 2. The compound of wherein Ris heterocyclyl which is pyridyl.3. The compound of claim 1 , wherein Ris —C(═O)—NRRwherein Ris H and Ris alkyl.4. The compound of claim 3 , wherein said Ralkyl is unsubstituted or substituted with an aryl substituent.5. The compound of claim 1 , wherein Ris H.6. The compound of claim 1 , wherein m is 0.7. The compound of claim 1 , wherein m is 1 claim 1 , and Ris selected from the group consisting of alkyl claim 1 , aryl claim 1 , hydroxyl claim 1 , and —S-alkyl; wherein said Ralkyl is hydroxymethyl and said Raryl is phenyl.8. The compound of claim 1 , wherein m is 2 claim 1 , and the two Rgroups together with the carbon atom to which both are attached form —C(═O)—.10. The compound of claim 1 , wherein Ris alkyl claim 1 , which is unsubstituted or substituted with at least one substituent selected from the group consisting of aryl and heteroaryl.11. The compound of claim 10 , wherein said Ris alkyl which is substituted with a heteroaryl selected from the group consisting of pyridyl claim 10 , thiazolyl claim 10 , and thiophenyl.12. The compound of claim 1 , selected from the group consisting of:N-[3-[6-(1-METHYLETHOXY)-3-PYRIDINYL]-1H-INDAZOL-5-YL]-4-(PHENYLMETHYL)-2-MORPHOLINECARBOXAMIDE;N-[3-[6-(1-METHYLETHOXY)-3-PYRIDINYL]-1H-INDAZOL-5-YL]-2-MORPHOLINECARBOXAMIDE;N-[3-(4-PYRIDINYL)-1H-INDAZOL-5-YL]-4-(4-THIAZOLYLMETHYL)-2-MORPHOLINECARBOXAMIDE;N-[3-(4-PYRIDINYL)-1H-INDAZOL-5-YL]-4-(3-THIENYLMETHYL)-2-MORPHOLINECARBOXAMIDE;4-[(2-FLUOROPHENYL)METHYL]-N-[3-(4-PYRIDINYL)-1H-INDAZOL-5-YL]-2-MORPHOLINECARBOXAMIDE;N-[3-(4-PYRIDINYL)-1H-INDAZOL-5-YL]-4-(2-PYRIDINYLMETHYL)-2- ...

FUSED PYRAZOLE DERIVATIVES AS NOVEL ERK INHIBITORS

Disclosed are the ERK inhibitors of Formula (I): (Formula (I)) and the pharmaceutically acceptable salts thereof. All substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of Formula (I). 3. The compound of wherein Ris heteroaryl claim 1 , wherein said heteroaryl group is unsubstituted or substituted by one to three Rgroups claim 1 , or alternatively two Rcan optionally be taken together with the carbon atoms to which they are attached to form a five- or six-membered cycloalkyl claim 1 , cycloalkenyl claim 1 , heterocyclyl claim 1 , heterocyclenyl claim 1 , arl or heteroaryl.8. A pharmaceutical composition comprising at least one compound of and a pharmaceutically acceptable carrier.9. A method of treating or preventing cancer in a mammal in need of such treatment that is comprised of administering to said mammal a therapeutically effective amount of a compound of .10. A method of treating cancer or preventing cancer in accordance with wherein the cancer is selected from cancers of the brain claim 9 , genitourinary tract claim 9 , lymphatic system claim 9 , stomach claim 9 , larynx and lung.11. A method of treating or preventing cancer in accordance with wherein the cancer is selected from histiocytic lymphoma claim 10 , lung adenocarcinoma claim 10 , small cell lung cancers claim 10 , pancreatic cancer claim 10 , liver cancer claim 10 , gastric cancer claim 10 , colon cancer claim 10 , multiple myeloma claim 10 , gliobastomas and breast carcinoma.12. A method of using the compound according to for the preparation of a medicament useful in treating or preventing cancer in a mammal in need of such treatment.13. A method of using the compound according to for the preparation of a medicament useful in inhibiting ERK in a mammal in need of such treatment.14. A method of using the compound according to for the preparation of a medicament useful in preventing or modulating metastasis of cancer in a mammal in need of such ...

INHIBITORS OF POLO-LIKE KINASE

The present invention provides compounds having a structure according to Formula (I): 19-. (canceled)11. The method of claim 10 , wherein the disease is an alpha-synucleinopathy.12. The method of claim 11 , wherein the disease is a member selected from the group consisting of Parkinson's disease claim 11 , Parkinson disease with dementia claim 11 , PD at risk syndrome claim 11 , dementia with Lewy bodies claim 11 , diffuse Lewy body disease claim 11 , Lewy body dementia claim 11 , cortical Lewy body disease claim 11 , senile dementia of Lewy type claim 11 , Lewy body variant of Alzheimer's disease claim 11 , diffuse Lewy body type of Alzheimer's disease claim 11 , combined Parkinson's disease and Alzheimer's disease claim 11 , multiple system atrophy claim 11 , striatonigral degeneration claim 11 , olivopontocerebellar atrophy claim 11 , and Shy-Drager syndrome.13. The method of claim 12 , wherein the disease is Parkinson's disease.15. The method of claim 14 , wherein the disease is an alpha-synucleinopathy.16. The method of claim 15 , wherein the disease is a member selected from the group consisting of Parkinson's disease claim 15 , Parkinson disease with dementia claim 15 , PD at risk syndrome claim 15 , dementia with Lewy bodies claim 15 , diffuse Lewy body disease claim 15 , Lewy body dementia claim 15 , cortical Lewy body disease claim 15 , senile dementia of Lewy type claim 15 , Lewy body variant of Alzheimer's disease claim 15 , diffuse Lewy body type of Alzheimer's disease claim 15 , combined Parkinson's disease and Alzheimer's disease claim 15 , multiple system atrophy claim 15 , striatonigral degeneration claim 15 , olivopontocerebellar atrophy claim 15 , and Shy-Drager syndrome.17. The method of claim 16 , wherein the disease is Parkinson's disease.19. The method of claim 18 , wherein the disease is an alpha-synucleinopathy.20. The method of claim 19 , wherein the disease is a member selected from the group consisting of Parkinson's disease claim 19 , ...

Novel compounds that are erk inhibitors

Disclosed are the ERK inhibitors of formula (1): and the pharmaceutically acceptable salts thereof, wherein: A is a five membered monocyclic heteroaryl ring; and B is a monocyclic heterocycloalkyl ring, or a monocyclic heterocycloalkenyl ring, or a bridged monocyclic heterocycloalkyl ring, or a fused (monocyclic heterocycloalkyl ring) cyclopropyl ring. Also disclosed are methods of treating cancer using the compounds of formula (1).

INDAZOLE DERIVATIVES USEFUL AS ERK INHIBITORS

The present invention provides a compound of the Formula I, or a pharmaceutically acceptable salt, solvate or ester thereof, wherein R, R, R, R, m and are as defined herein. The compounds are ERK inhibitors. Also disclosed are pharmaceutical compositions that comprise the above compounds, and methods of treating cancer using the same. 2. The compound of claim 1 , wherein R is H.5. The compound of claim 1 , wherein Ris aryl claim 1 , wherein when said aryl has two substituents on adjacent ring atoms claim 1 , said substituents together with the ring atoms to which they are attached claim 1 , optionally form a five- or six-membered heteroaryl.7. The compound of claim 1 , wherein Ris H.8. The compound of claim 1 , wherein said Ralkyl is substituted with one to three substituents independently selected from the group consisting of heterocyclyl claim 1 , aryl claim 1 , heteroaryl claim 1 , hydroxyl claim 1 , and halo claim 1 , wherein when each of said heterocyclyl claim 1 , aryl or heteroaryl has two substituents on adjacent ring atoms claim 1 , said substituents together with the ring atoms to which they are attached claim 1 , optionally form a five- or six-membered heteroaryl or a six-membered aryl.9. The compound of wherein:{'sup': '3', 'said heterocyclyl and heteroaryl substituent of said Ralkyl is selected from the group consisting of: imidazolyl, benzimidazolyl, 1H-benzimidazol-1-yl, pyrazolyl, 1,2,4-triazolyl, 1H-1,2,4-triazol-1-yl, 6-oxo-1(6H)-pyridazinyl, indazolyl, 1H-indazol-1-yl, 2H-indazol-1-yl, 2H-indazol-2-yl, 2-oxo-1(2H)-pyridinyl, pyrazolopyridinyl, 1H-pyrazolo[4,3-b]pyridin-1-yl, 2H-pyrazolo[3,4-b]pyridin-2-yl, 1H-pyrazolo[3,4-c]pyridin-1-yl, 2H-pyrazolo[3,4-c]pyridin-2-yl, 1H-pyrazolo[3,4-b]pyridin-1-yl, 1H-pyrazolo[4,3-c]pyridin-1-yl, indolyl, 1H-indol-1-yl, imidazopyridinyl, 2-oxo-1H-indol-1-yl, 1H-imidazo[4,5-b]pyridin-1-yl, 3H-imidazo[4,5-b]pyridin-3-yl, 1H-imidazo[4,5-c]pyridin-1-yl, and 2-oxo-1(2H)-quinolinyl, each of which is unsubstituted or ...

COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR

Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases. 2. The method of in which Ris a substituted aryl.3. The method of in which the substituted aryl is a fluorobenzene radical.4. The method of in which the substituted aryl is a difluorobenzene radical.5. The method of in which Ris hydrogen.6. The method of in which Ris a lower alkyl.7. The method of in which the lower alkyl is n-propyl.8. The method of in which Ris fluoro.9. The method of in which Ris a difluorobenzene radical and Ris hydrogen.10. The method of in which the remainder of the compound includes a heteroaryl moiety.11. The method of in which the heteroaryl moiety includes two nitrogen atoms.12. The method of in which the patient's cancer has metastasized to the patient's brain. This application is a U.S. Divisional Application of U.S. application Ser. No. 11/473,347 filed Jun. 21, 2006, which claims the benefit of U.S. Prov. App. No. 60/692,960, filed Jun. 22, 2005, and U.S. Prov. App. No. 60/731,528, filed Oct. 28, 2005, which are incorporated herein by reference in their entireties and for all purposes.The present invention relates to kinases and compounds which modulate kinases, and uses therefor. Particular embodiments contemplate disease indications which are amenable to treatment by modulation of kinase activity by the compounds of the present invention.The information provided herein is intended solely to assist the understanding of the reader. None of the information provided nor references cited is admitted to be prior art to the present invention. Each of the references cited herein is incorporated in its entirety.Receptor protein kinases regulate key signal transduction cascades that control or are involved in the control of a plethora of physiological functions including cellular growth and proliferation, cell differentiation, cellular development, cell division, ...

INHIBITORS OF POLO-LIKE KINASE

The present invention provides compounds having a structure according to Formula (I): 3. The compound of claim 2 , wherein A is a member selected from pyrrolidinyl claim 2 , piperidinyl claim 2 , morpholinyl claim 2 , thiomorpholinyl claim 2 , N-alkyl-piperazinyl claim 2 , oxazolidinyl claim 2 , thiazolidinyl claim 2 , pyridyl claim 2 , pyrimidinyl claim 2 , pyridazinyl claim 2 , pyrazinyl claim 2 , triazinyl claim 2 , pyrrolyl claim 2 , imidazolyl claim 2 , pyrazolyl claim 2 , thiazolyl claim 2 , isothiazolyl claim 2 , oxazolyl claim 2 , isoxazolyl claim 2 , thiadiazolyl claim 2 , triazolyl and tetrazolyl claim 2 , wherein A is substituted or unsubstituted.4. The compound of claim 3 , wherein A is a substituted or unsubstituted ring selected from the group consisting of pyridyl claim 3 , pyrazolyl and imidazolyl.5. The compound of claim 4 , wherein A is a substituted or unsubstituted ring selected from the group consisting of pyridin-3-yl claim 4 , pyridin-4-yl claim 4 , pyrazol-4-yl and imidazol-1-yl.10. The compound of claim 8 , wherein the compound is selected from the group consisting of:(S)-6a-ethyl-5-methyl-2-(2-phenyl-1H-imidazol-1-yl)-6a,7,9,10-tetrahydro-[1,4]oxazino[3,4-h]pteridin-6(5H)-one,(S)-6a-ethyl-5-methyl-2-(5-(thiazol-2-yl)-1H-pyrazol-4-yl)-6a,7,9,10-tetrahydro-[1,4]oxazino[3,4-h]pteridin-6(5H)-one,(S)-6a-ethyl-5,8-dimethyl-2-(2-phenyl-1H-imidazol-1-yl)-7,8,9,10-tetrahydro-5H-pyrazino[2,1-h]pteridin-6(6aH)-one,(S)-2-(2-(2,4-difluorophenyl)-1H-imidazol-1-yl)-6a-ethyl-5-methyl-6a,7,9,0-tetrahydro-[1,4]oxazino[3,4-h]pteridin-6(5H)-one,(S)-6a-ethyl-2-(2-(5-fluoropyridin-2-yl)-1H-imidazol-1-yl)-5-methyl-6a,7,9,10-tetrahydro-[1,4]oxazino[3,4-h]pteridin-8(5H)-one,(S)-6a-ethyl-5-methyl-2-(2-(thiazo-2-yl)-1H-imidazol-1-yl)-6a,7,9,10-tetrahydro-[1,4]oxazino[3,4-h]pteridin-6(5H)-one,(S)-6a-ethyl-5-methyl-2-(3-phenylpyridin-4-yl)-6a,7,9,10-tetrahydro-[1,4]oxazino[3,4-h]pteridin-6(5H)-one,(S)-6a-ethyl-5-methyl-2-(2-phenylpyridin-3-yl)-6a,7,9,10-tetrahydro-[1,4 ...

Method And Apparatus For Notifying Friend

A method for notifying a friend includes configuring a friend notifying input box in a text editing interface; initiating a friend association based on a keyword input by a user and a friend list of the user, according to the keyword input in the friend notifying input box by the user; determining at least one friend to be selected from the friend list of the user according to the keyword; determining at least one friend selected by the user from the at least one friend as at least one target friend; sending a friend notification to the at least one target friend after the user finishes editing a text and posts the text. An apparatus for notifying a friend is provided. 1. A method for notifying a friend , comprising:configuring a friend notifying input box in a text editing interface;initiating a friend association based on a keyword input by a user and a friend list of the user, according the keyword input in the friend notifying input box by the user;determining at least one friend to be selected from the friend list of the user according to the keyword;determining at least one friend selected by the user from the at least one friend as at least one target friend; andsending a friend notification to the at least one target friend after the user finishes editing a text and posts the text.2. The method of claim 1 , wherein determining at least one friend to be selected from the friend list of the user according to the keyword comprises:determining a friend as the friend to be selected when a name of the friend comprises the keyword; displaying the at least one friend to be selected as a list at a current cursor position.3. The method of claim 1 , wherein determining at least one friend selected by the user from the at least one friend as at least one target friend comprises:configuring a label indicating a friend for the friend selected by the user from the at least one friend to be selected, and the label comprising contact information of the friend; determining ...

Compounds and methods for kinase modulation, and indications therefor

Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.

METHOD AND TERMINAL FOR EDITING INFORMATION IN SOCIAL NETWORK SERVICE APPLICATIONS

The present disclosure discloses a method of editing information in a social network service (“SNS”) application, and a terminal for the same. The method can comprise: sending from a command terminal to an execution terminal a multimedia information obtaining command while the command terminal is executing an editing operation in an editing area of an SNS application; obtaining multimedia information by the execution terminal in accordance with the multimedia information obtaining command; sending the obtained multimedia information to the command terminal; and inserting the multimedia information by the command terminal into the editing area of the SNS application. The present disclosure accomplishes information editing via inter-terminal interaction, simplifies the process of information editing operation, increases the convenience of information editing, and enhances the SNS application's user loyalty. 1. A social network service (“SNS”) application information editing method comprising:sending a multimedia information obtaining command from a command terminal to an execution terminal associated with the command terminal when the command terminal is executing an editing operation in an editing area of the SNS application;obtaining multimedia information by the execution terminal in accordance with the multimedia information obtaining command;sending the multimedia information from the execution terminal to the command terminal; andentering the multimedia information into the editing area of the SNS application by the command terminal.2. The method of claim 1 , wherein sending the multimedia information obtaining command comprises:sending a search request from the command terminal to a server to search for the execution terminal associated with the command terminal, the search request comprising identification of and account information associated with the SNS application;searching by the server terminals logged into the SNS application using the account ...

METHOD, DEVICE, AND TERMINAL FOR SNS SYSTEM APPLICATION PROMPT

A method, device, and terminal for social network service (“SNS”) system application prompt are described. The method may include: obtaining location information associated with a current geographical location of a terminal; generating prompt information corresponding to the location information; and outputting the prompt information, wherein the prompt information prompts a user to start an SNS system application. The method increases SNS system applications' user loyalty and rate of utilization. 1. A social network service (SNS) system application prompt method comprising:obtaining location information associated with a current geographical location of a terminal,generating prompt information corresponding to the location information, andoutputting the prompt information, wherein the prompt information prompts a user to start an SNS system application.2. The method of claim 1 , wherein generating prompt information corresponding to the location information comprises:determining an administrative region corresponding to the location information, andgenerating prompt information corresponding to the administrative region, whereinthe prompt information comprises a regional identifier of the administrative region comprising at least one of: a name associated with the administrative region, an icon associated with the administrative region, a name of a construction within the administrative region, and an icon associated with a construction within the administrative region.3. The method of claim 1 , comprising:recording obtained geographical location information associated with the terminal.4. The method of claim 3 , comprising:determining whether the location information associated with the current geographical location of the terminal is different from previously recorded geographical location information associated with the terminal, whereingenerating prompt information corresponding to the location information comprisesgenerating the prompt information upon the ...

ONLINE SOCIAL NETWORKING INTERACTION METHOD AND RELATED DEVICE AND SYSTEM

An online social networking interaction method and related device and system comprise: an initiation terminal sending a command carrying an event location and a target terminal identification entered by a user on a social networking platform to a service device; the service device sending a message carrying the event location to a target terminal based on the target terminal identification after receiving the command; the target terminal detecting whether the target terminal is present at the event location after receiving the message carrying the event location, and sending a notification that the target terminal is present at the event location to the service device if the target terminal is present; the service device sending the notification that the target terminal is present at the event location to the initiation terminal; and the target terminal detecting whether the target terminal is not present at the event location, and prompting the user to perform one or more social networking interaction operations if the target terminal is not present. The present disclosure can remind users to perform social networking interaction operations after social networking events, so that information about the social networking events can be shared with friends. 1. An online social networking interaction method comprising:receiving a message carrying an event location from a service device,detecting whether a target terminal is present at the event location,sending a notification that the target terminal is present at the event location to the service device if the target terminal is present at the event location,detecting whether the target terminal is not present at the event location, andprompting a user to perform one or more social networking operations if the target terminal is not present at the event location.2. The method of claim 1 , comprising:receiving an invitation to a social networking event from the service device,detecting whether the target terminal has ...

METHOD, RELATED DEVICE, AND SYSTEM FOR INTER-TERMINAL INTERACTIONS

The present disclosure discloses an inter-terminal interaction method, and related device and system, the method comprising: receiving by a second terminal a media resource insertion command entered by a user on a social networking platform; inserting the user's social networking platform account information into the command by the second terminal; sending the command from the second terminal to a service device; searching by the service device terminal identification information associated with the account information; generating prompt information by the service device; sending from the service device to a first terminal the prompt information based on the terminal identification information associated with the account information; presenting by the first terminal media resources based on the prompt information; sending from the first terminal to the service device media resources selected by the user from the presented media resources; receiving by the service device from the first terminal the media resources; sending from the service device to the second terminal the media resources; inserting the media resources into the social networking platform by the second terminal. The present disclosure can reduce manual participation by users and increase the efficiency of inter-terminal interactions. 1. An inter-terminal interaction method comprising:receiving a media resource insertion command entered by a user on a social networking platform,inserting the user's social networking platform account information into the media resource insertion command,sending the media resource insertion command carrying the user's social networking platform account information to a service device, enabling the service device to search terminal identification information associated with the account information, to generate prompt information, to send the prompt information to a first terminal based on the terminal identification information associated with the account information, and ...

LYRIC PAGE GENERATION METHOD AND LYRIC PAGE GENERATION APPARATUS

The present disclosure discloses a lyrics page generation method and a lyrics page generation apparatus, belonging to the field of network technologies. The method includes: receiving a lyrics page generation instruction, the lyrics page generation instruction being used for instructing to display a lyrics page of a selected multimedia file list; obtaining a lyrics file of at least one multimedia file in the multimedia file list; and generating a lyrics page according to the lyrics file of the at least one multimedia file, the lyrics page including lyrics information of the at least one multimedia file. The present disclosure provides a brand-new lyrics display manner, which can achieve an effect similar to a lyrics book, so that a user can collect lyrics that the user likes, for subsequent appreciation, so that an application becomes more humanistic, and an amount of information that a lyrics page can provide is greatly increased. 1. A method for generating a lyrics page , the method comprising: receiving a lyrics page generation instruction, the lyrics page generation instruction being used for generating a lyrics page of a selected multimedia file list;', 'obtaining a lyrics file of at least one multimedia file in the multimedia file list;', 'generating a lyrics page according to the lyrics file of the at least one multimedia file, the lyrics page comprising lyrics information of the at least one multimedia file; and', 'displaying the lyrics page., 'at a device having one or more processors and memory2. The method according to claim 1 , wherein the lyrics information displayed on the lyrics page is lyrics information of a specified part of the multimedia file of the at least one multimedia file claim 1 , and after the generating a lyrics page according to the lyrics file of the at least one multimedia file claim 1 , the method further comprises:loading and displaying lyrics information of one or more portions of the multimedia file other than the specified part ...

METHODS AND SYSTEMS FOR AGGREGATING USER GENERATED CONTENT

A method and system for aggregating user generated content (UGC) are disclosed. The method includes receiving a request for creating UGC, the request including content to be created and identification of a subject event; generating the UGC, the UGC being associated with the subject event; adding data related to the UGC to data describing the subject event; and sending data related to the subject event to users, including the UGC related to the subject event. Embodiments consistent with the present disclosure thus provide various aggregations of UGC associated with a subject event and improve user experience in social networking systems. 1. A method for aggregating user generated content (UGC) , comprising:receiving a request for creating UGC, including content to be created and identification of a subject event, from a user;generating the UGC, the UGC being associated with the subject event;adding data related to the UGC to data describing the subject event; andsending data related to the subject event to users, including the UGC associated with the subject event.2. The method according to claim 1 , further comprising:sending the UGC to users, including the associated subject event.3. The method according to claim 2 , further comprising:adding identification of the UGC to a table listing data associated with the subject event.4. The method according to claim 3 , wherein the identification of the UGC includes identification of the user who authored the UGC.5. A server for aggregating user generated content (UGC) claim 3 , comprising:a content request interface module configured to receive a request for creating UGC including content to be created and identification of a subject event from a user;a content creation module configured to generate the UGC, the UGC being associated with the subject event, and to add data related to the UGC to data describing the subject event; anda subject event transmitting module configured to send data related to the subject event to ...

POSITIVE ELECTRODE MATERIAL FOR RECHARGEABLE LITHIUM ION BATTERIES

A bimodal lithium transition metal oxide based powder mixture comprising a first and a second lithium transition metal oxide based powder. The first powder comprises a material A having a layered crystal structure comprising the elements Li, a transition metal based composition M and oxygen and has a particle size distribution with a span <1.0. The second powder has a monolithic morphology and a general formula LiN′O, wherein −0.03≤b≤0.10, and N′=NiM″CoE, wherein 0.30≤x≤0.92, 0.05≤y≤0.40, 0.05≤z≤0.40 and 0≤d≤0.10, with M″ being one or both of Mn or Al, and E being a dopant different from M″. The first powder has an average particle size D50 between 10 and 40 μm. The second powder has an average particle size D50 between 2 and 4 μm. The weight ratio of the second powder in the bimodal mixture is between 20 and 60 wt %. 19-. (canceled)10. A bimodal lithium transition metal oxide based powder mixture for a rechargeable battery , comprising:{'sub': 1+a', '1−m', 'm', '2, 'a first lithium transition metal oxide based powder, comprising particles of a material A having a layered crystal structure comprising the elements Li, a transition metal based composition M and oxygen, wherein the particles of material A have a general formula LiCoM′O, with −0.05≤a≤0.05 and 0≤m≤0.05, the material A having a D50≥20 μm, and wherein M′ is one or more metals of the group consisting of Al, Ca, Si, Ga, B, Ti, Mg, W, Zr, Cr and V, the first powder having a particle size distribution with a span <1.0; and'}{'sub': 1+b', '1-b', '2', 'x', 'y', 'z', 'd, 'a second lithium transition metal oxide based powder, comprising a material B having a monolithic morphology, said particles having a general formula LiN′O, wherein 0.03≤b≤0.10, and N′=NiM″CoE, wherein 0.30≤x≤0.92, 0.05≤y≤0.40, 0.05≤z≤0.40 and 0≤d≤0.10, with M″ being one or both of Mn or Al, and with E being a dopant different from M″, the first powder having an average particle size D50 between 10 and 40 μm, the second powder having an average ...

PRECURSORS FOR CATHODE MATERIAL WITH IMPROVED SECONDARY BATTERY PERFORMANCE AND METHOD TO PREPARE THE PRECURSORS

A crystalline precursor compound for manufacturing a lithium transition metal based oxide powder usable as an active positive electrode material in lithium-ion batteries, the precursor having a general formula M(O)(OH)(CO), with 030.10cm/g. 116-. (canceled)17. A crystalline precursor compound for manufacturing a lithium transition metal based oxide powder usable as an active positive electrode material in lithium-ion batteries , the precursor having a general formula M(O)(OH)(CO) , with 0≤x≤1 , 0 Подробнее

CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS

Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described. 2. The compound or pharmaceutically acceptable salt of claim 1 , wherein Ris hydrogen claim 1 , cyano claim 1 , halo claim 1 , hydroxy claim 1 , carboxy claim 1 , optionally substituted alkoxy claim 1 , optionally substituted aryloxy claim 1 , optionally substituted alkoxycarbonyl claim 1 , optionally substituted alkyl claim 1 , optionally substituted aryl claim 1 , optionally substituted heteroaryl claim 1 , optionally substituted amino claim 1 , optionally substituted acyl claim 1 , optionally substituted alkoxycarbonyl claim 1 , optionally substituted aminocarbonyl claim 1 , optionally substituted aminosulfonyl claim 1 , optionally substituted carbamimidoyl claim 1 , or optionally substituted alkynyl.3. (canceled)4. The compound or pharmaceutically acceptable salt of claim 2 , wherein Ris optionally substituted aryl claim 2 , optionally substituted heterocycloalkyl claim 2 , or optionally substituted heteroaryl.5. (canceled)6. The compound or pharmaceutically acceptable salt of claim 1 , wherein R claim 1 , R claim 1 , R claim 1 , and Rare independently hydrogen claim 1 , halo claim 1 , cyano claim 1 , optionally substituted alkoxy claim 1 , or optionally substituted alkyl.7. (canceled)8. (canceled)9. The compound or pharmaceutically acceptable salt of wherein R claim 1 , R claim 1 , R claim 1 , and Rare independently hydrogen claim 1 , cyano claim 1 , halo claim 1 , optionally substituted alkoxy claim 1 , optionally substituted alkyl claim 1 , optionally substituted acyl claim 1 , optionally substituted alkoxycarbonyl claim 1 , optionally substituted aminocarbonyl claim 1 , or optionally substituted aminosulfonyl.1012.-. (canceled)13. The compound or pharmaceutically acceptable salt of claim 1 , wherein Ris hydrogen claim 1 , optionally substituted lower alkyl claim 1 , optionally substituted cycloalkyl claim 1 , optionally substituted ...

CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS

Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described. 145.-. (canceled)47. The method of claim 46 , wherein Ris hydrogen claim 46 , cyano claim 46 , halo claim 46 , hydroxy claim 46 , carboxy claim 46 , optionally substituted alkoxy claim 46 , optionally substituted aryloxy claim 46 , optionally substituted alkoxycarbonyl claim 46 , optionally substituted alkyl claim 46 , optionally substituted aryl claim 46 , optionally substituted heteroaryl claim 46 , optionally substituted heterocycloalkyl claim 46 , optionally substituted amino claim 46 , optionally substituted acyl claim 46 , optionally substituted alkoxycarbonyl claim 46 , optionally substituted aminocarbonyl claim 46 , optionally substituted aminosulfonyl claim 46 , optionally substituted carbamimidoyl claim 46 , or optionally substituted alkynyl.48. The method of claim 46 , wherein Ris optionally substituted aryl claim 46 , optionally substituted heterocycloalkyl claim 46 , or optionally substituted heteroaryl.49. The method of claim 46 , wherein Ris optionally substituted morpholinyl claim 46 , optionally substituted piperazinyl claim 46 , optionally substituted pyrrolidinyl claim 46 , optionally substituted piperidinyl claim 46 , optionally substituted imidazolyl claim 46 , optionally substituted pyrazolyl claim 46 , or optionally substituted pyridyl.50. The method of claim 46 , wherein R claim 46 , R claim 46 , R claim 46 , and Rare independently hydrogen claim 46 , halo claim 46 , cyano claim 46 , optionally substituted alkoxy claim 46 , or optionally substituted alkyl.51. The method of claim 46 , wherein R claim 46 , R claim 46 , R claim 46 , and Rare independently hydrogen or halo.52. The method of claim 46 , wherein R claim 46 , R claim 46 , R claim 46 , and Rare independently hydrogen claim 46 , cyano claim 46 , halo claim 46 , optionally substituted alkoxy claim 46 , optionally substituted alkyl claim 46 , optionally substituted ...

Time flight depth camera and multi-frequency modulation and demodulation distance measuring method

A time flight depth camera and a distance measuring method are provided. The time flight depth camera comprises: a light source for emitting a pulse beam to an object; an image sensor comprising at least one pixel, wherein each of the at least one pixel comprises taps, and each tap is used for acquiring a charge signal based on a reflected pulse beam due to the pulse beam reflected from the object to be measured or a charge signal of background light; and a processing circuit configured to control the light source to emit pulse beams in adjacent frame periods, receive charge signals of the taps in the adjacent frame periods, determine whether the charge signals comprise the charge signal of the reflected pulse beam, and calculate a time of flight of the pulse beam and/or a distance to the object according to a result of the determining.

SYSTEM AND METHOD FOR EVALUATING PERFORMANCE AND EVOLUTION ABILITY OF NETWORK ADDRESS AND IDENTIFICATION SCHEMES

In a method, formal descriptions of network address and identification schemes are received. Then validity and completeness of the formal descriptions are verified. The network address and identification schemes are scheduled into a final description after the validity and completeness of the formal descriptions are verified. The final description is resolved into an applicable network address. Then the applicable network address and identification scheme is applied to a test network and the test network runs. The running performance of the test network is measured. The measurements are analyzed and sent to evaluating performance and evolution ability of the network address and identification schemes. 1. A system , comprising:a managing and evaluating center, comprising:an input unit configured for receiving formal descriptions of network address and identification schemes;a verifying unit in communication with the input unit and configured for verifying validity and completeness of the formal descriptions; anda scheduling unit in communication with the verifying unit and configured for scheduling the network address and identification schemes into a final description after the validity and completeness of the formal descriptions are verified; andan evaluating unit;a control center, comprising:a script resolving unit in communication with the scheduling unit and configured for resolving the final description into an applicable network address and identification scheme; anda resource allocating unit;a test network, the resource allocating unit being in communication with the script resolving unit and the test network, and configured for applying the applicable network address and identification scheme to the test network to run the test network; anda measurement center, comprising:a measuring unit in communication with the test network and configured for measuring running performance of the test network; andan analyzing unit in communication with the measuring unit ...

ANION EXCHANGE MEMBRANES BASED ON POLYMERIZATION OF LONG CHAIN ALPHA OLEFINS

Described herein are cationic polymers having a plurality of quaternary amino groups, methods of making such polymers, and uses of such polymers as ion exchange membranes in electrochemical devices. 2. The method of claim 1 , wherein each Ris independently (C-C)alkylene.3. The method of claim 1 , wherein each Ris independently (C-C)alkylene.4. The method of claim 1 , wherein the cationic amine compound that is reacted with the precursor polymer is of Formula (VII){'br': None, 'sup': 5', '6', '5', '+', '5', '+, 'sub': 2', '2', 'v', '3, 'N(R)—R—{[N(R)]—R}—[N(R)]\u2003\u2003 (VII)'} [{'sup': '5', 'each Ris independently alkyl;'}, {'sup': '6', 'each Ris independently alkylene;'}, 'v is an integer in a range of 0 to 10; and', 'the cationic groups have corresponding anionic counter ions., 'wherein'}6. The cationic polymer of claim 5 , wherein each Ris independently (C-C)alkylene.7. The cationic polymer of claim 5 , wherein each Ris independently (C-C)alkylene.8. The cationic polymer of claim 5 , wherein:{'sup': '1', 'Ris independently aralkyl or substituted aralkyl;'}{'sup': '4', 'claim-text': [{'br': None, 'sup': 3', '+', '+', '+, 'sub': 3', '2', '2', 'm', '3', '2', '2', 'm', '0-8', '3', '3, 'R—N(CH)—(CH)—{[N(CH)]—(CH)}—[N(CH)],'}, {'br': None, 'sup': 3', '+', '+', '+, 'sub': 3', '2', '2', '6-8', '3', '2', '2', '6-8', 'v', '3', '3, '—R—N(CH)—(CH)—{[N(CH)]—(CH)}—[N(CH)]or'}, {'br': None, 'sup': 3', '+', '+', '+, 'sub': 3', '2', '2', '6-8', '3', '2', '2', '6-8', '3-8', '3', '3, '—R—N(CH)—(CH)—{[N(CH)]—(CH)}-[N(CH)];'}], 'each Ris independently a cationic group of the formula 'v is a variable in a range of 0 to 10; and', 'm is a variable in a range of 4 to 9;'}the cationic group has corresponding anionic counter ions.9. The cationic polymer of claim 8 , wherein the anionic counter ions are chloride claim 8 , bromide claim 8 , iodide claim 8 , bicarbonate claim 8 , carbonate claim 8 , hydroxide claim 8 , alkoxide claim 8 , acetate or sulfate.10. A membrane comprising the ...

BATTERY CAPACITY GRADING CIRCUIT

A battery capacity grading circuit includes a power supply, a first switch module, an inductor, a sampling module, a battery, a first control module, a second control module, and a second switch module. The first switch module is electrically coupled with the power supply, the inductor and the first control module. The sampling module is electrically coupled with inductor, the second switch module, and the first control module. The second switch module is electrically coupled with the battery and the second control module. The battery is electrically coupled with first control module. The second control module is electrically coupled with the first control module. The power supply charges the battery through the first switch module, the inductor, the sampling module, and the second switch module. The battery discharges to the power supply through the second switch module, the sampling module, the inductor, and the first switch module. 1100. A battery capacity grading circuit () , comprising:{'b': 10', '20', '1', '30', '40', '50', '60', '70, 'a power supply (), a first switch module (), an inductor (L), a sampling module (), a battery (), a first control module (), a second control module (), and a second switch module ();'}{'b': 20', '10', '1', '50', '30', '1', '70', '50', '70', '40', '60', '40', '50', '60', '50', '10', '40', '20', '1', '30', '70', '40', '10', '70', '30', '1', '20, 'wherein the first switch module () is electrically coupled with the power supply (), the inductor (L) and the first control module (); the sampling module () is electrically coupled with the inductor (L), the second switch module (), and the first control module (); the second switch module () is electrically coupled with the battery () and the second control module (); the battery () is electrically coupled with first control module (); the second control module () is electrically coupled with the first control module (); the power supply () charges the battery () through the first ...

CONTROL DEVICE FOR A GIMBAL AND METHOD OF CONTROLLING THE SAME

The present invention discloses a controlling device, a gimbal on which the controlling device is applied and a method for controlling a gimbal. The gimbal, for controlling an optical device to perform an action, may comprise a controlling device, a controlling assembly connected with the controlling device, and a performing assembly connected with the controlling assembly; wherein the controlling device may comprise a rocker for receiving an action instruction and generating a control instruction to be sent to the controlling assembly, the rocker may comprise a rocker handle and a potentiometer assembly connected with the rocker handle; the controlling assembly may be configured for generating a performing instruction for implementing a corresponding action according to the control instruction sent by the controlling device, and send the performing instruction to the performing assembly; the performing assembly may be configured for implementing a directional control for the optical device according to the performing instruction. The gimbal according to the present invention is easy to operate and has a good hand feeling, since the rocker is utilized to send the control instruction. 1. A gimbal for controlling an optical device , said gimbal comprising:a rocker for receiving an action instruction and generating a control instruction, wherein the rocker comprises a rocker handle and a potentiometer assembly operably connected to the rocker handle;a controlling assembly configured to (1) receive the control instruction from the rocker, and (2) generate, based on the control instruction, a performing instruction for controlling the optical device; anda performing assembly configured to (1) receive the performing instruction from the controlling assembly, and (2) implement a directional control of the optical device in accordance with the performing instruction.2. The gimbal according to claim 1 , wherein the potentiometer assembly comprises a first potentiometer ...

TRANSPORTING APPARATUS WITH SHOCK ABSORBING ELEMENTS

The present disclosure provides a transporting apparatus. The transporting apparatus can include the following components: a first frame support configured to support an object; a second frame support configured to roll the transporting apparatus and to move relative to the first frame support; and a plurality of shock absorbing elements positioned between the first frame support and the second frame support. 1. A transporting apparatus , comprising:a first frame support configured to support an object;a second frame support configured to roll the transporting apparatus; anda plurality of shock absorbing elements positioned between the first frame support and the second frame support.2. The transporting apparatus of claim 1 , wherein each of the plurality of shock absorbing elements comprises a polymer.3. The transporting apparatus of claim 2 , wherein the polymer comprises chloroprene rubber claim 2 , butyl rubber claim 2 , butadiene rubber claim 2 , ethylene propylene claim 2 , nitrile rubber claim 2 , fluorocarbon claim 2 , hydrogenated nitrile claim 2 , poly-acrylate claim 2 , silicone claim 2 , or a combination thereof.4. The transporting apparatus of claim 2 , wherein the polymer has a shore hardness from about 5 shore 00 to about 90 shore A.5. The transporting apparatus of claim 1 , wherein each of the plurality of shock absorbing elements comprises a spherical component claim 1 , an elliptical component claim 1 , a disk shape component claim 1 , a cubical component claim 1 , a conical component claim 1 , a pyramidal component claim 1 , a cylindrical component claim 1 , or a combination thereof.6. The transporting apparatus of claim 1 , wherein each of the plurality of shock absorbing elements comprises a hollow element with a gas inside.7. The transporting apparatus of claim 6 , wherein the gas comprises air with a pressure between about 11 psi and about 18 psi.8. The transporting apparatus of claim 1 , wherein each of the plurality of shock absorbing ...

FEATURE RELATIONSHIP RECOMMENDATION METHOD, APPARATUS, COMPUTING DEVICE, AND STORAGE MEDIUM

Disclosed herein are methods, systems, and apparatus, including computer programs encoded on computer storage media, for generating relationship recommendations. One of the methods includes: determining, by a computing device, parameter entities that comprise event entities associated with node entities; constructing, by the computing device, a knowledge graph based on relationships between the parameter entities and predetermined operator entities; extracting, by the computing device, a newly added relationship from the knowledge graph based on an inference rule; and providing, by the computing device, a relationship recommendation corresponding to the newly added relationship. 1. A computer-implemented method for generating relationship recommendations based on a knowledge graph , comprising:determining, by a computing device, parameter entities that comprise event entities associated with node entities;constructing, by the computing device, a knowledge graph based on relationships between the parameter entities and predetermined operator entities;extracting, by the computing device, a newly added relationship from the knowledge graph based on an inference rule; andproviding, by the computing device, a relationship recommendation corresponding to the newly added relationship.2. The method according to claim 1 , further comprising:determining a label corresponding to the newly added relationship based on a classification model, wherein the label is a white label indicating that the newly added relationship has no fraudulent risk, or a black label indicating that the newly added relationship has fraudulent risk.3. The method according to claim 2 , further comprising:determining that the newly added relationship corresponds to a white label;determining an importance degree of the newly added relationship based on the classification model; andadding, to the knowledge graph, the newly added relationship when the importance degree is greater than a predetermined ...

Precursors for Lithium Transition Metal Oxide Cathode Materials for Rechargeable Batteries

A particulate precursor compound for manufacturing a lithium transition metal oxide powder for use as an active positive electrode material in lithium-ion batteries, the precursor having the general formula NiMnCoAO(OH), wherein 0.150.7, and the XRD pattern being free of peaks belonging to either one or both of a spinel and an oxyhydroxide compound. 1. A particulate precursor compound for manufacturing a lithium transition metal oxide powder for use as an active positive electrode material in lithium-ion batteries , the precursor compound having a general formula NiMnCoAO(OH) , wherein 0.150.7 , wherein the XRD pattern is free of peaks belonging to one or both of a spinel and an oxyhydroxide compound.2. The particulate precursor compound of claim 1 , wherein the precursor compound has an XRD pattern with twin peaks at 2θ=38±0.5° claim 1 , the twin peaks having a left peak and a right peak claim 1 , wherein the left peak belongs to an XRD pattern of a β(II)-Me(OH)structure and the right peak belongs to an XRD pattern of an oxidized β(II)-Me(OH)structure claim 1 , and wherein the weight % of the β(II)-Me(OH)structure in the precursor compound is more than 0 wt % and less than 48 wt %.3. The particulate precursor compound of claim 1 , wherein the precursor compound has an ...

CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS

Chemical entities that are effective as kinase inhibitors, pharmaceutical compositions and methods of treatment are disclosed. The chemical entities disclosed specifically inhibit signal transduction and cellular proliferation by modulating the activity of protein kinases to regulate and modulate abnormal or inappropriate cell proliferation, differentiation, or metabolism. The compounds include a pyrido[3,2-d]pyrimidine scaffold substituted with aromatic and heteroaromatic moieties. 3. (canceled)5. (canceled)8. (canceled)9. (canceled)10. The compound or pharmaceutically acceptable salt of claim 1 , wherein m is 1 claim 1 , 2 claim 1 , or 3; and at least one Q is E.11. The compound or pharmaceutically acceptable salt of claim 1 , wherein n is 1 and Z is optionally substituted heterocycloalkyl.12. The compound or pharmaceutically acceptable salt of claim 11 , wherein Z is optionally substituted piperazinyl.13. (canceled)17. The compound or pharmaceutically acceptable salt of claim 16 , wherein Ris hydrogen claim 16 , cyano claim 16 , halo claim 16 , hydroxy claim 16 , —CONH claim 16 , optionally substituted alkoxy claim 16 , or optionally substituted cycloalkyloxy.18. (canceled)19. The compound or pharmaceutically acceptable salt of claim 16 , wherein R claim 16 , R claim 16 , and Rare independently hydrogen claim 16 , cyano claim 16 , halo claim 16 , hydroxy claim 16 , carboxy claim 16 , optionally substituted alkoxy claim 16 , optionally substituted lower alkyl claim 16 , optionally substituted heterocycloalkyl claim 16 , optionally substituted aryl claim 16 , optionally substituted heteroaryl claim 16 , optionally substituted amino claim 16 , optionally substituted acyl claim 16 , optionally substituted alkoxycarbonyl claim 16 , or optionally substituted aminocarbonyl.20. (canceled)21. The compound or pharmaceutically acceptable salt of claim 19 , wherein Rand Rare hydrogen claim 19 , and Ris optionally substituted morpholinyl claim 19 , optionally substituted ...

SUBSTITUTED QUINOXALINES AS B-RAF KINASE INHIBITORS

Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described. 152-. (canceled)54. The compound or pharmaceutically acceptable salt of claim 53 , wherein Ris hydrogen claim 53 , cyano claim 53 , optionally substituted alkoxy claim 53 , optionally substituted aryloxy claim 53 , optionally substituted amino claim 53 , optionally substituted alkyl claim 53 , optionally substituted heterocycloalkyl claim 53 , optionally substituted aryl claim 53 , optionally substituted pyridyl claim 53 , optionally substituted pyrazinyl claim 53 , optionally substituted pyrimidinyl claim 53 , optionally substituted imidazolyl claim 53 , optionally substituted isoxazolyl claim 53 , optionally substituted oxazolyl claim 53 , optionally substituted tetrazolyl claim 53 , optionally substituted pyridazinyl claim 53 , or optionally substituted triazolyl.55. The compound or pharmaceutically acceptable salt of claim 54 , wherein Ris optionally substituted aryl claim 54 , optionally substituted heterocycloalkyl claim 54 , optionally substituted pyridyl claim 54 , optionally substituted pyrazinyl claim 54 , optionally substituted pyrimidinyl claim 54 , optionally substituted imidazolyl claim 54 , optionally substituted isoxazolyl claim 54 , optionally substituted oxazolyl claim 54 , optionally substituted tetrazolyl claim 54 , or optionally substituted triazolyl.56. The compound or pharmaceutically acceptable salt of claim 53 , wherein R claim 53 , R claim 53 , R claim 53 , and Rare independently hydrogen claim 53 , halo claim 53 , cyano claim 53 , optionally substituted alkoxy claim 53 , or optionally substituted alkyl.57. The compound or pharmaceutically acceptable salt of claim 56 , wherein R claim 56 , R claim 56 , R claim 56 , and Rare independently hydrogen or halo.58. The compound or pharmaceutically acceptable salt of claim 53 , wherein Ris hydrogen claim 53 , cyano claim 53 , or optionally substituted alkyl.59. The compound or ...

CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS

Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described. 2. The compound or pharmaceutically acceptable salt of claim 1 , wherein Ris hydrogen claim 1 , cyano claim 1 , optionally substituted alkoxy claim 1 , optionally substituted aryloxy claim 1 , optionally substituted amino claim 1 , optionally substituted alkyl claim 1 , optionally substituted heterocycloalkyl claim 1 , optionally substituted aryl claim 1 , or optionally substituted heteroaryl.3. The compound or pharmaceutically acceptable salt of claim 2 , wherein Ris optionally substituted aryl claim 2 , optionally substituted heterocycloalkyl claim 2 , or optionally substituted heteroaryl.4. The compound or pharmaceutically acceptable salt of claim 3 , wherein Ris optionally substituted morpholinyl claim 3 , optionally substituted piperazinyl claim 3 , optionally substituted pyrrolidinyl claim 3 , optionally substituted piperidinyl claim 3 , optionally substituted imidazolyl claim 3 , optionally substituted pyrazolyl claim 3 , or optionally substituted pyridyl.5. The compound or pharmaceutically acceptable salt of claim 1 , wherein R claim 1 , R claim 1 , R claim 1 , and Rare independently hydrogen claim 1 , halo claim 1 , cyano claim 1 , optionally substituted alkoxy claim 1 , or optionally substituted alkyl.6. The compound or pharmaceutically acceptable salt of claim 5 , wherein R claim 5 , R claim 5 , R claim 5 , and Rare independently hydrogen or halo.7. The compound or pharmaceutically acceptable salt of claim 6 , wherein R claim 6 , R claim 6 , R claim 6 , and Rare hydrogen.8. The compound or pharmaceutically acceptable salt of claim 5 , wherein Ris hydrogen or halo.9. The compound or pharmaceutically acceptable salt of claim 8 , wherein Ris halo.10. The compound or pharmaceutically acceptable salt of claim 9 , wherein Ris fluoro or chloro.11. The compound or pharmaceutically acceptable salt of claim 1 , wherein Ris hydrogen claim 1 , ...

CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS

Chemical entities that are quinoxaline kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described. 2. The compound or pharmaceutically acceptable salt of claim 1 , wherein Ris hydrogen claim 1 , cyano claim 1 , halo claim 1 , hydroxy claim 1 , carboxy claim 1 , optionally substituted alkoxy claim 1 , optionally substituted aryloxy claim 1 , optionally substituted alkoxycarbonyl claim 1 , optionally substituted alkyl claim 1 , optionally substituted cycloalkyl claim 1 , optionally substituted aryloxy claim 1 , optionally substituted aryl claim 1 , optionally substituted heteroaryl claim 1 , optionally substituted amino claim 1 , optionally substituted acyl claim 1 , optionally substituted alkoxycarbonyl claim 1 , optionally substituted aminocarbonyl claim 1 , optionally substituted aminosulfonyl claim 1 , optionally substituted carbamimidoyl claim 1 , or optionally substituted alkynyl.3. The compound or pharmaceutically acceptable salt of claim 2 , wherein Ris hydrogen claim 2 , cyano claim 2 , optionally substituted alkoxy claim 2 , optionally substituted cycloalkyloxy claim 2 , optionally substituted aryloxy claim 2 , optionally substituted amino claim 2 , optionally substituted alkyl claim 2 , optionally substituted heterocycloalkyl claim 2 , optionally substituted aryl claim 2 , or optionally substituted heteroaryl.4. The compound or pharmaceutically acceptable salt of claim 3 , wherein Ris optionally substituted aryl claim 3 , optionally substituted heterocycloalkyl claim 3 , or optionally substituted heteroaryl.5. The compound or pharmaceutically acceptable salt of claim 4 , wherein Ris optionally substituted morpholinyl claim 4 , optionally substituted piperazinyl claim 4 , optionally substituted pyrrolidinyl claim 4 , optionally substituted piperidinyl claim 4 , optionally substituted imidazolyl claim 4 , optionally substituted pyrazolyl claim 4 , or optionally substituted pyridyl.6. The compound or pharmaceutically ...

COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR

Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases. 120.-. (canceled)23. The method according to claim 21 , wherein the Raf mediated disease or condition is a neurological disease selected from the group consisting of multi-infarct dementia claim 21 , head injury claim 21 , spinal cord injury claim 21 , Alzheimer's disease and Parkinson's disease.24. The method according to claim 21 , wherein the Raf mediated disease or condition is a neoplastic disease selected from the group consisting of melanoma claim 21 , glioma claim 21 , sarcoma claim 21 , colorectal cancer claim 21 , lung cancer claim 21 , breast cancer claim 21 , pancreatic cancer claim 21 , thyroid cancer claim 21 , renal cancer claim 21 , ovarian cancer claim 21 , histiocytic lymphoma claim 21 , neurofibromatosis claim 21 , acute myeloid leukemia claim 21 , myelodysplastic syndrome claim 21 , leukemia claim 21 , tumor angiogenesis claim 21 , medullary thyroid cancer claim 21 , carcinoid claim 21 , small cell lung cancer and pheochromocytoma.25. The method according to claim 21 , wherein the Raf mediated disease or condition is a pain of neuropathic or inflammatory origin selected from the group consisting of acute pain claim 21 , chronic pain claim 21 , cancer-related pain and migraine.26. The method according to claim 21 , wherein the Raf mediated disease or condition is a cardiovascular disease selected from the group consisting of heart failure claim 21 , ischemic stroke claim 21 , cardiac hypertrophy claim 21 , thrombosis claim 21 , atherosclerosis and reperfusion injury.27. The method according to claim 21 , wherein the Raf mediated disease or condition is an inflammatory disease selected from the group consisting of ipsoriasis claim 21 , arthritis and autoimmune diseases and conditions claim 21 , osteoarthritis claim 21 , endometriosis claim 21 , scarring claim 21 , ...

CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS

Chemical entities based on quinoxaline that are kinase inhibitors are described. Specifically, quinoxaline derivatives of Formula I, containing a diarylamide or diarylurea substructure that inhibit Braf mutant kinase activity, pharmaceutical compositions containing the inhibitor compounds and methods of treatment of cancer comprising administering an effective amount of the Braf inhibitor compound are described. 177.-. (canceled)78. A compound selected from the group consisting of:1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(3-(quinoxaline-6-carbonyl)phenyl)urea;1-(3-(3-morpholinoquinoxaline-6-carbonyl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea;1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(3-(3-morpholinoquinoxaline-6-carbonyl)phenyl)urea;1-(3-fluorophenyl)-3-(3-(3-(pyrrolidin-1-yl)quinoxaline-6-carbonyl)phenyl)urea;1-(3-(3-(pyrrolidin-1-yl)quinoxaline-6-carbonyl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea;1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(3-(3-(pyridin-3-yl)quinoxaline-6-carbonyl)phenyl)urea;1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(3-(3-(1-methyl-1H-pyrazol-4-yl)quinoxaline-6-carbonyl)phenyl)urea;1-(3-(3-(1H-pyrazol-4-yl)quinoxaline-6-carbonyl)phenyl)-3-(4-chloro-3-(trifluoromethyl)phenyl)urea;1-(4-fluoro-3-(3-morpholinoquinoxaline-6-carbonyl)phenyl)-3-(3-fluorophenyl)urea;1-(4-fluoro-3-(3-morpholinoquinoxaline-6-carbonyl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea;1-(3-fluoro-5-(3-morpholinoquinoxaline-6-carbonyl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea;1-(4-chloro-3-fluorophenyl)-3-(4-fluoro-3-(3-morpholinoquinoxaline-6-carbonyl)phenyl)urea;1-(3-chloro-4-fluorophenyl)-3-(4-fluoro-3-(3-morpholinoquinoxaline-6-carbonyl)phenyl)urea; and1-(3,4-difluorophenyl)-3-(4-fluoro-3-(3-((2-hydroxyethyl)amino)quinoxaline-6-carbonyl)phenyl)urea;or a pharmaceutically acceptable salt thereof.79. The compound of claim 78 , wherein the compound is 1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(3-(quinoxaline-6-carbonyl)phenyl)urea claim 78 , or a pharmaceutically acceptable salt thereof.80 ...

ELECTRICAL CONNECTOR AND ELECTRICAL CONNECTOR ASSEMBLY

An electrical connector includes multiple electrical modules sequentially stacked along a vertical direction. Each electrical module includes an insulating block being arc-shaped, a row of conductors fixed to the insulating block, and a first shielding member. The row of conductors includes multiple first grounding conductors and multiple pairs of first signal conductors arranged on the insulating block along a left-right direction. The two first signal conductors in a same pair of first signal conductors have a same length. The first shielding member has a first main body portion overlapping with a projection of one pair of first signal conductors in the vertical direction. The first shielding member and each conductor bend and extend downward from a top thereof and backward from a front thereof to be arc-shaped. The first contact portions of the row of conductors located on the same electrical module are located on a same horizontal plane. 1. An electrical connector , comprising:a plurality of electrical modules sequentially stacked along a vertical direction and fixed by at least one fixing mechanism, wherein each of the electrical modules comprises an insulating block being arc-shaped, a row of conductors fixed to the insulating block and arranged along a left-right direction perpendicular to the vertical direction, and at least one first shielding member provided to cover the insulating block, a front-rear direction is defined to be perpendicular to the vertical direction and the left-right direction, the first shielding member and each of the conductors bend and extend downward from a top thereof and backward from a front thereof to be arc-shaped, each of the conductors comprises a first contact portion, a first conductive portion and a connecting portion connected to the first contact portion and the first conductive portion, and the first contact portions of the row of conductors located on the same one of the electrical modules are located on a same ...

FLAVONOID IL-17A INHIBITORS

The present invention describes compounds according to formula I: 2. The compound of claim 1 , wherein at least one of R claim 1 , R claim 1 , R claim 1 , and Ris selected from the group consisting of —O—C-C-alkyl claim 1 , —O—C-C-cycloalkyl claim 1 , halogen claim 1 , —NH claim 1 , —NH—C-C-alkyl claim 1 , —NH(C-C-alkyl) claim 1 , —NH—CO—C-C-alkyl claim 1 , —NHSOC-C-alkyl claim 1 , —NHSON(C-C-alkyl) claim 1 , —NHCONH—C-C-alkyl claim 1 , —NHCON(C-C-alkyl) claim 1 , and —NH-aryl.3. The compound of claim 1 , wherein W is selected from —CH— and —N—.6. The compound of claim 4 , wherein Ar is a bicyclic fused heteroaryl group or a bicyclic fused heterocycloalkyl aryl group.8. The compound of claim 5 , wherein at least one of R claim 5 , R claim 5 , R claim 5 , and Ris selected from the group consisting of —O—C-C-alkyl claim 5 , —O—C-C-cycloalkyl claim 5 , halogen claim 5 , —NH claim 5 , —NH—C-C-alkyl claim 5 , —NH(C-C-alkyl) claim 5 , —NH—CO—C-C-alkyl claim 5 , —NHSO—C-C-alkyl claim 5 , —NHSON(C-C-alkyl) claim 5 , —NHCONH—C-C-alkyl claim 5 , —NHCON(C-C-alkyl) claim 5 , and —NH-aryl.9. The compound of claim 4 , wherein W is —CH—.10. The compound of claim 4 , wherein X and Y are —CH—.12. The compound of claim 11 , wherein Ar is a bicyclic fused heteroaryl group or a bicyclic fused heterocycloalkyl aryl group.15. The compound of claim 11 , wherein W is —O—.17. The method of claim 16 , wherein R claim 16 , R claim 16 , R claim 16 , and Rare —OH claim 16 , and R claim 16 , R claim 16 , and Rare independently selected from the group consisting of —H claim 16 , —C-Calkyl claim 16 , —OH claim 16 , —OMe claim 16 , and halogen.18. The method of claim 16 , wherein Ris —OH.19. The method of claim 16 , wherein R claim 16 , R claim 16 , and Rare —OH.20. The method of claim 16 , wherein W is —O—.21. The method of claim 16 , wherein the compound is cyanidin.22. The method of claim 16 , wherein the compound is delphinidin.23. The method of claim 16 , wherein the IL-17A-mediated disease is ...

Reaction Cuvette Loading Device and Chemiluminescence Immunoassay Apparatus

Provided are a reaction cuvette loading device and a fully automatic chemiluminescence immunoassay apparatus. The reaction cuvette loading device comprises a transmission mechanism and a push mechanism, wherein the transmission mechanism comprises a baseplate and a first horizontal transmission mechanism provided on the baseplate; the push mechanism comprises a support assembly, a second horizontal transmission mechanism provided on the support assembly, and a push rod connected to the second horizontal transmission mechanism; and the push mechanism further comprises a direction guiding control block comprising a starting end provided at a terminal point of a cuvette pushing stroke of the push rod, a termination end provided at a starting point of the cuvette pushing stroke of the push rod, and a return track provided between the starting end and the termination end and bypassing the cuvette pushing stroke, and the separation distance between the starting end and termination end is not less than one vessel position and not more than two vessel positions. 1. A reaction cuvette loading device , comprising:a transmission mechanism comprising a bottom plate and a first horizontal transmission mechanism positioned on the bottom plate; and a bracket assembly;', 'a second horizontal transmission mechanism positioned on the bracket assembly;', 'a push rod positioned on the bracket assembly and connected to the second horizontal transmission mechanism; and', 'a guiding control block comprising: a starting end positioned on a terminal point of a cuvette pushing stroke of the push rod; a terminating end positioned on a start point of the cuvette pushing stroke of the push rod; and a return track positioned between the starting end and the terminating end and bypassing the cuvette pushing stroke, wherein a distance between the starting end and terminating end is greater than one cuvette position and less than two cuvette positions., 'a pushing mechanism comprising2. The ...

INFORMATION SHARING METHOD, APPARATUS AND COMPUTER DEVICE

Described is an information sharing method and apparatus, which are directed to information published by a user in a social network. For information published by a user in a social network, when a sharing instruction of the user is received, a selection box comprising one or more sharing targets is displayed for the user, each sharing target has its corresponding social network, and the social network corresponding to the sharing target includes a social network which published the information; when a submission instruction of the user is received, the information is sent to a sharing target selected by the user from the selection box. By using the present method, the spread of information can be accelerated, and the implementation is simple and convenient. 1. (canceled)2. A method of sharing content , the method comprising:receiving a first user selection of a sharing graphic that is displayed in association with content to be shared by a user;displaying a sharing target selection interface after the first user selection of the sharing graphic is received, the sharing target selection interface being configured to concurrently display a plurality of social network service sharing targets and a search notification region;receiving a second selection of one of the plurality of social network service sharing targets via the sharing target selection interface;receiving a third selection of the search notification region of the sharing target selection interface; anddisplaying a search box in the sharing target selection interface in response to the third selection when the one of the plurality of social network service sharing targets is friends of a first social network service.3. The method of claim 2 , further comprising:displaying a comment interface that includes a target selection graphic in response to receiving the first user selection of the sharing graphic.4. The method of claim 2 , wherein the content is posed by the user on a second social network service ...

Doped and Coated Lithium Transition Metal Oxide Cathode Materials for Batteries in Automotive Applications

A lithium metal oxide powder for use as a cathode material in a rechargeable battery, consisting of Li metal oxide core particles having a general formula Li(NiMnCoZrM′)0Ar; wherein Al0is attached to the surface of the core particles; wherein 0≦d≦0.08, 0.2≦x≦0.9, 0 Подробнее

CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS

Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described. 3. (canceled)57.-. (canceled)9. The compound or salt of claim 8 , wherein R claim 8 , R claim 8 , R claim 8 , R claim 8 , R claim 8 , R claim 8 , R claim 8 , R claim 8 , R claim 8 , R claim 8 , R claim 8 , Rand Rare each independently selected from the group consisting of hydrogen claim 8 , cyano claim 8 , halo claim 8 , C-Calkyl claim 8 , C-Chaloalkyl claim 8 , C-Calkoxy claim 8 , 3- to 6-membered cycloalkyl claim 8 , aminocarbonyl and amino.1015.-. (canceled)16. The compound or salt of claim 8 , wherein Xis N.17. The compound or salt of claim 8 , wherein Lis selected from —O— claim 8 , —N(R)— claim 8 , —C(O)N(R)— and —N(R)C(O)—.18. (canceled)2021.-. (canceled)22. The compound or salt of claim 1 , wherein Lis a bond or Lis a bond.2324.-. (canceled)25. The compound or salt of claim 1 , wherein m is 1 claim 1 , 2 claim 1 , 3 claim 1 , 4 claim 1 , or 5 and wherein Q is independently selected at each occurrence from cyano claim 1 , halo claim 1 , hydroxy claim 1 , azido claim 1 , nitro claim 1 , carboxy claim 1 , oxo claim 1 , sulfinyl claim 1 , sulfanyl claim 1 , sulfonyl claim 1 , alkoxy claim 1 , alkyl claim 1 , haloalkyl claim 1 , alkenyl claim 1 , alkynyl claim 1 , amino claim 1 , acyl claim 1 , alkoxycarbonyl claim 1 , aminocarbonyl claim 1 , aminosulfonyl claim 1 , carbamimidoyl and E.26. The compound or salt of claim 25 , wherein at least one Q is E.2733.-. (canceled)35. (canceled)3741.-. (canceled)42. The compound or salt of claim 1 , wherein R claim 1 , R claim 1 , R claim 1 , R claim 1 , R claim 1 , Rand Rare independently selected from the group consisting of hydrogen claim 1 , cyano claim 1 , halo claim 1 , hydroxy claim 1 , optionally substituted alkyl claim 1 , optionally substituted aryl claim 1 , optionally substituted heteroaryl claim 1 , and optionally substituted amino.4344.-. (canceled)45. The compound or salt of claim 1 , ...

CONTROL DEVICE FOR A GIMBAL AND METHOD OF CONTROLLING THE SAME

A gimbal for controlling an optical device includes a rocker for receiving an action instruction and generating a control instruction. The rocker comprises a keypad for switching between two or more operating modes of the gimbal. The operating modes of the gimbal comprise (1) a follow mode in which a shooting direction of the optical device follows a moving direction of the gimbal and (2) a locked mode in which the shooting direction of the optical device is locked in a specified direction regardless of movement of the gimbal. The gimbal further includes a controlling assembly configured to (1) receive the control instruction from the rocker, and (2) generate, based on the control instruction, a performing instruction for controlling the optical device. 1. A gimbal for controlling an optical device , said gimbal comprising:a rocker for receiving an action instruction and generating a control instruction, wherein the rocker comprises a keypad for switching between two or more operating modes of the gimbal, the operating modes of the gimbal comprising: (1) a follow mode in which a shooting direction of the optical device follows a moving direction of the gimbal and (2) a locked mode in which the shooting direction of the optical device is locked in a specified direction regardless of movement of the gimbal; anda controlling assembly configured to (1) receive the control instruction from the rocker, and (2) generate, based on the control instruction, a performing instruction for controlling the optical device.2. The gimbal according to claim 1 , wherein the rocker further comprises a rocker handle for controlling an attitude of the optical device.3. The gimbal according to claim 1 , wherein the control instruction is generated based at least in part on a duration of the action instruction.4. The gimbal according to claim 1 , wherein the action instruction is a short press action instruction and the control instruction is configured to cause the gimbal to switch between ...

METHOD FOR CONSTRUCTING INTERNET ADDRESS SCHEMES USING XML

In a method for constructing Internet protocol (IP) addresses using extensible markup language (XML), an XML schema associated with a predetermined type of Internet address schemes is defined using a universal description standard. The XML schema includes attribute elements covering core attributes of constructing the Internet address schemes. The attribute elements include: construct_method, representing a function constructing method for the Internet address schemes, which is an enumeration type stored in a function association table. The function association table stores a collection of function constructing methods and a collection of functions for constructing the Internet address schemes, each of which is associated with a corresponding function constructing method. Then, values of the attribute elements for constructing the Internet address schemes are input. Next, the values are resolved and the corresponding function is called to construct the Internet address schemes according to the values. 1. A method for constructing Internet protocol (IP) addresses using extensible markup language (XML) , the method comprising:defining an XML schema associated with a predetermined type of Internet address schemes using a universal description standard, the XML schema comprising attribute elements covering core attributes of constructing the Internet address schemes, the attribute elements comprising: construct_method, representing a function constructing method for the Internet address schemes, which is an enumeration type stored in a function association table, the function association table storing a collection of function constructing methods and a collection of functions for constructing the Internet address schemes, each of which is associated with a corresponding function constructing method;inputting values of the attribute elements for constructing the Internet address schemes; andresolving the values and calling the corresponding function to construct the ...

Motion Sensor for Occupancy Detection and Intrusion Detection

A motion sensor has an infrared detector with a first set of detector elements coupled to a first channel and a second set of detector elements coupled to a second channel. A first optical subsystem directs infrared radiation from a first number of monitored volumes to the infrared detector and a second optical subsystem directs infrared radiation from a second number of monitored volumes to the infrared detector. Intrusion detection circuitry is coupled to both channels of the infrared detector and selects a set of peaks in the first channel and the second channel. It then calculates an alternation score based on a number of alternating peaks in the set of peaks, and indicates an intrusion detection based, at least in part, on the alternation score. The circuitry also determines a peak-to-peak period for the first channel and calculates a slope-synchrony measurement to modify the alternation score. 1. A motion sensor comprising:an infrared detector comprising a first set of detector elements and a second set of detector elements;a first optical subsystem adapted to direct infrared radiation from a first row of monitored volumes spaced at a first pitch in a first direction onto the first set of detector elements, and to direct infrared radiation from a second row of monitored volumes spaced at the first pitch in the first direction, and offset from the first row of monitored volumes in the first direction, onto the second set of detector elements, the first row and the second row each consisting of a first number of monitored volumes; anda second optical subsystem adapted to direct infrared radiation from a third row of monitored volumes spaced at a second pitch in the first direction onto the first set of detector elements, and to direct infrared radiation from a fourth row of monitored volumes spaced at the second pitch in the first direction, and offset from the third row of monitored volumes in the first direction, onto the second set of detector elements, the ...

Method, system and client for uploading image, network server and computer storage medium

The present disclosure relates to the technical field of wireless network communications, and provides a method, system and client for uploading an image, a network server and a computer storage medium. The method includes: a client determines an image to be uploaded, generates a unique image identifier corresponding to the image to be uploaded, and transmits an image detection request to a network server; the network server detects whether there is an image having the same image identifier in the network server according to the image identifier included in the image detection request, and returns a detection result to the client; when the detection result is that there is not an image having the same image identifier in the network server, the client uploads the image to be uploaded in the form of multi-part uploading to the network server; and after the image to be uploaded is uploaded successfully, the network server records the image identifier, and returns an upload success response to the client. The present disclosure avoids a repeated uploading of a same image, so that the upload rate is improved, a great deal of network traffic bandwidth is saved, and user experiences are improved. 1. A method for uploading an image , comprising:determining, by a client, an image to be uploaded, generating a unique image identifier corresponding to the image to be uploaded, and transmitting an image detection request to a network server;detecting, by the network server, whether there is an image having the same image identifier in the network server according to the image identifier included in the image detection request, and returning a detection result to the client;when the detection result is that there is not an image having the same image identifier in the network server, uploading, by the client, the image to be uploaded in the form of multi-part uploading to the network server; andafter the image to be uploaded is uploaded successfully, recording, by the network ...

Microrna and uses thereof in prevention and/or treatment of fibroplasia medical sign and/or syndrome

Provided are microRNA from a rhodiola root and uses thereof in the prevention and/or the treatment of a fibroplasia medical sign and/or syndrome.

Adsorption Mechanism, Cleaning Device, Chemiluminescence Detector and Cleaning Method

The present disclosure relates to a magnetic microbeads adsorption mechanism, which is configured to adsorb a magnetic microbeads in a reaction cup and is provided with a cup inlet station and a cup outlet station; the magnetic microbeads adsorption mechanism includes a pedestal, a turntable and multiple magnetic adsorption components; the turntable is rotatably mounted on the pedestal; the turntable can drive the reaction cup to rotate around a central axis of the turntable; the multiple magnetic adsorption components are arranged on a mounting circumference of the pedestal at intervals; the mounting circumference and rotation track of the reaction cup are concentrically arranged; and during a process when the reaction cup rotates from the cup inlet station to the cup outlet station, the adsorption height of the magnetic microbeads relative to cup bottom of the reaction cup can be changed. 1. A magnetic microbeads adsorption mechanism , which is configured to adsorb a magnetic microbeads in a reaction cup in a rotation movement and is provided with a cup inlet station and a cup outlet station ,the magnetic microbeads adsorption mechanism comprising a pedestal and a plurality of magnetic adsorption components, wherein the plurality of magnetic adsorption components are arranged at intervals on a same mounting circumference of the pedestal; the mounting circumference and a rotation track of the reaction cup are concentrically arranged; andduring a process when the reaction cup rotates from the cup inlet station to the cup outlet station passing through the plurality of magnetic adsorption components, an adsorption height of the magnetic microbeads is able to be changed.2. The magnetic microbeads adsorption mechanism as claimed in claim 1 , wherein for a single reaction cup in the rotation movement claim 1 , the adsorption height of the magnetic microbeads is increased first and then is decreased.3. The magnetic microbeads adsorption mechanism as claimed in claim 1 , ...

Measuring Chamber, Working Method of Measuring Chamber, Chemiluminescence Measurement Method of Measuring Chamber and Chemiluminescence Detector

The present disclosure relates to a measuring chamber, a working method of the measuring chamber, a chemiluminescence measurement method of the measuring chamber and a chemiluminescence detector. The measuring chamber includes a dark chamber, a first substrate nozzle, a photomultiplier detection component, a waste liquor adsorption needle component, a reaction cup turntable and a plurality of reaction cup processing stations; the reaction cup turntable is provided in the measuring chamber rotationally; and the plurality of reaction cup processing stations are sealed in a mutually light-isolated manner. When the instrument works, reaction cups in the reaction cup turntable are moved in the dark chamber; and after the reaction cups are moved to corresponding processing stations for processing the reaction cups, the plurality of different processing stations for processing, the reaction cups may simultaneously process the reaction cups moved to the corresponding reaction cup processing stations. 1. A measuring chamber for processing multiple reaction cup processing stations in parallel , comprising a dark chamber , a first substrate nozzle , a photomultiplier detection component , a waste liquor adsorption needle component , a reaction cup turntable and a plurality of reaction cup processing stations , the reaction cup turntable being provided in the measuring chamber rotationally , wherein the plurality of reaction cup processing stations are sealed in a mutually light-isolated manner ,2. The measuring chamber as claimed in claim 1 , further comprising a bottom plate claim 1 , an inner shell claim 1 , an outer shell and an upper cover claim 1 , wherein the bottom plate claim 1 , the outer shell and the upper cover are enclosed into a holding space; the reaction cup turntable and the inner shell are provided in the holding space; the reaction cup turntable is provided between the inner shell and the outer shell along a radial direction of the reaction cup turntable; ...

APPLICATION OF COMPOUND OR TRADITIONAL CHINESE MEDICINE EXTRACT IN PREPARATION OF NUCLEIC ACID DELIVERY AGENT, AND RELATED PRODUCTS

The present application relates to extracting a plurality of compounds from a traditional Chinese medicine, or synthesizing a compound capable of promoting nucleic acid delivery, and utilizing the extracted compound, or a plurality of combinations to promote absorption and entry of a nucleic acid such as sRNA into a target cell, and to facilitate the entry of a nucleic acid into a target site in a subject in need thereof 166-. (canceled)70. The method of claim 67 , wherein in the compound claim 67 ,{'sub': 10-20', '10-20, 'A is selected from the group consisting of H, Calkyl and Calkenyl;'}{'sub': 2', '10-20', '10-20, 'B is selected from the group consisting of H, —NH, Calkyl and Calkenyl;'}{'sub': 10-20', '10-20', '3', '1-4, 'sup': '+', 'Q is selected from the group consisting of H, —OH, Calkyl and Calkenyl, and —NR, wherein R is H or Calkyl.'}71. The method of claim 70 , wherein in the compound claim 70 ,{'sub': 15-18', '15-18, 'A is selected from the group consisting of H, a straight-chain Calkyl group and a straight-chain Calkenyl group;'}{'sub': 2', '15-18', '15-18, 'B is selected from the group consisting of H, —NH, a straight-chain Calkyl group and a straight-chain Calkenyl group;'}{'sub': 15-18', '15-18', '3', '1-4, 'sup': '+', 'Q is selected from the group consisting of H, —OH, a straight-chain Calkyl group and a straight-chain Calkenyl group, and —NR wherein R is H or a Calkyl group; and'}the alkenyl group in the A, B, Q has 1-5 double bonds.72. The method of claim 71 , wherein in the A claim 71 , B claim 71 , and Q claim 71 , the alkenyl group has 1-4 double bonds and is in a Z configuration.73. The method of claim 72 , wherein the alkenyl group in the A claim 72 , B claim 72 , and Q has 1-3 double bonds and is in a Z configuration.75. The method of claim 67 , wherein the nucleic acid is a single stranded or double stranded small nucleic acid with a length of 14-32 bp claim 67 , 16-28 bp or 18-24 bp.76. The method of claim 67 , wherein the nucleic acid is ...

APPARATUS FOR AUTOMATIC PLACEMENT OF GASKETS ON A HOUSING

An apparatus for automatic placement of gaskets on a housing includes a base, the second feeding mechanism, a first detecting member, a bearing mechanism, an assembly mechanism, and a controller. The first detecting member can detect the position of the gaskets relative to the preset position. The detected results are transmitted to the controller by the first detecting member. The controller controls the second feeding mechanism to accurately adjust the position of the gaskets to preset position. Therefore, a projection of the gasket is accurately engaged in a mounting hole of the housing by the assembly mechanism. 1. An apparatus for automatic placement of gaskets on a housing , the apparatus comprising:a base;a second feeding mechanism positioned on the base, the second feeding mechanism having a second drive member connected to a rotary drive member, with a suction member connected to the rotary drive member;a first detecting member positioned on the base;a bearing mechanism positioned on the base;an assembly mechanism; anda controller electrically connected to the second feeding mechanism, the first detecting member, the bearing mechanism and the assembly mechanism;wherein, the bearing mechanism is positioned closer to the base than the suction member;wherein, after a gasket is retrieved by the suction member, the position of the retrieved gasket is detected by the first detecting member and transmitted to the controller, the controller then instructs the rotary drive member to adjust the position of the retrieved gasket to a preset position and release the retrieved gasket to the bearing mechanism; andwherein, the assembly mechanism retrieves the released gasket from the bearing mechanism and moves the retrieved gasket from the bearing mechanism to the housing and places the retrieved gasket into a mounting hole on the housing.2. The apparatus for automatic placement of gaskets on a housing as claimed in claim 1 , wherein the apparatus for automatic placement ...

METHODS, APPARATUS, AND TERMINAL DEVICES OF IMAGE PROCESSING

Methods, apparatuses, and terminal devices of processing an image are provided. A region for superimposing audio related information is preset on a capturing interface in a terminal device. The obtained audio related information is superimposed onto the region. And a captured image superimposed with the audio related information is outputted, so that the image captured at the terminal device can display various types of information on the captured image. By publishing the image containing the audio related information, friends of the user can feel the environment of where the user is located in combination with the image. 1. An image processing method , comprising:receiving an operation instruction for a multimedia capturing application in a terminal device from a user, in response to the operation instruction, capturing an image via a capturing unit in the terminal device, and presetting a region on a capturing interface for superimposing audio related information;obtaining audio signal of a song from an external environment via an audio-signal obtaining unit in the terminal device, and obtaining the audio related information of the song according to the audio signal;detecting a superimposing instruction inputted by the user, and in response to the superimposing instruction, superimposing the obtained audio related information onto the preset region on the capturing interface; anddetecting a capturing instruction inputted by the user, and in response to the capturing instruction, outputting a captured image superimposed with the audio related information.2. The method according to claim 1 , wherein claim 1 , after the obtaining of the audio related information of the song claim 1 , the method further comprises:adjusting a format of the audio related information into a preset displaying format.3. The method according to claim 1 , wherein claim 1 , after the superimposing of the obtained audio related information onto the region on the capturing interface claim 1 , ...

Sample Rack Loading System and Loading Method, and Chemiluminescence Detector

The present disclosure relates to a sample rack loading system and loading method, and a chemiluminescence detector. The loading system includes: a sample rack storage device, provided with multiple sample holders for storing sample racks; a sample rack transmission device, comprising a rail component and a sample rack block piece mechanism; and a sample rack transfer device, transfers the sample racks between the sample rack storage device and the sample rack transmission device; the sample rack block piece mechanism is configured to block or unblock transmission passages of the rail component; and a guide block is arranged on the sample rack transfer device. When transfer rails of the sample rack transfer device are in abutment with the transmission passages, the guide block drives the sample rack block piece mechanism to unblock the transmission passages.

COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR

Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases. 19. The compound according to wherein Ris optionally substituted Calkyl claim 18 , optionally substituted cycloalkyl claim 18 , optionally substituted heterocycloalkyl claim 18 , optionally substituted aryl claim 18 , optionally substituted heteroaryl claim 18 , or substituted methyl claim 18 , wherein methyl is substituted with optionally substituted cycloalkyl claim 18 , optionally substituted heterocycloalkyl claim 18 , optionally substituted aryl claim 18 , or optionally substituted heteroaryl.20. The compound of claim 19 , wherein Ris other than hydrogen.2139.-. (canceled) This application is a continuation of U.S. application Ser. No. 12/906,980 filed Oct. 18, 2010, which is a divisional of U.S. application Ser. No. 11/473,347 filed Jun. 21, 2006, now issued as U.S. Pat. No. 7,836,288, which claims the benefit under 35 U.S.C. § 119(e) of U.S. Provisional Application No. 60/692,960, filed Jun. 22, 2005, and U.S. Provisional Application No. 60/731,528, filed Oct. 28, 2005, which are incorporated herein by reference in their entireties and for all purposes.The present invention relates to kinases and compounds which modulate kinases, and uses therefore. Particular embodiments contemplate disease indications which are amenable to treatment by modulation of kinase activity by the compounds of the present invention.The information provided herein is intended solely to assist the understanding of the reader. None of the information provided nor references cited is admitted to be prior art to the present invention. Each of the references cited herein is incorporated in its entirety.Receptor protein kinases regulate key signal transduction cascades that control or are involved in the control of a plethora of physiological functions including cellular growth and proliferation, cell ...

Inter-platform information sharing system and method, server, computer storage medium

Disclosed is an inter-platform information sharing system, including an interface module, a control module and a database, wherein the interface module is configured to receive information obtained through a first platform and acquire the information from the database and synchronize the acquired information with the counterpart on a second platform, or receive information obtained through the second platform and acquire the information from the database and synchronize the acquired information with the counterpart on the first platform, and the control module is configured to control the interface module to receive the information and acquire the information from the database, and control the database to store the obtained information. In addition, an inter-platform information sharing method, a server and a computer storage medium are also provided.

INHIBITORS OF POLO-LIKE KINASE

The present invention provides compounds having a structure according to Formula (I): 7. The compound of claim 1 , wherein the compound is selected from the group consisting of:(S)-6a-ethyl-5-methyl-2-(2-phenyl-1H-imidazol-1-yl)-6a,7,9,10-tetrahydro-[1,4]oxazino[3,4-h]pteridin-6(5H)-one,(S)-6a-ethyl-5-methyl-2-(5-(thiazol-2-yl)-1H-pyrazol-4-yl)-6a,7,9,10-tetrahydro-[1,4]oxazino[3,4-h]pteridin-6(5H)-one,(7R)-7-ethyl-5-methyl-8-(tetrahydrofuran-3-yl)-2-(5-(thiazol-2-yl)-1H-pyrazol-4-yl)-7,8-dihydropteridin-6(5H)-one,(S)-6a-ethyl-5,8-dimethyl-2-(2-phenyl-1H-imidazol-1-yl)-7,8,9,10-tetrahydro-5H-pyrazino[2,1-h]pteridin-6(6aH)-one,(S)-2-(2-(2,4-difluorophenyl)-1H-imidazol-1-yl)-6a-ethyl-5-methyl-6a,7,9,10-tetrahydro-[1,4]oxazino[3,4-h]pteridin-6(5H)-one,(S)-6a-ethyl-2-(2-(5-fluoropyridin-2-yl)-1H-imidazol-1-yl)-5-methyl-6a,7,9,10-tetrahydro-[1,4]oxazino[3,4-h]pteridin-6(5H)-one,(S)-6a-ethyl-5-methyl-2-(2-(thiazol-2-yl)-1H-imidazol-1-yl)-6a,7,9,10-tetrahydro-[1,4]oxazino[3,4-h]pteridin-6(5H)-one,(R)-7-ethyl-2-(2-(4-fluorophenyl)-1H-imidazol-1-yl)-5-methyl-8-(1-methyl-1H-pyrazol-4-yl)-7,8-dihydropteridin-6(5H)-one,(S)-6a-ethyl-5-methyl-2-(3-phenylpyridin-4-yl)-6a,7,9,10-tetrahydro-[1,4]oxazino[3,4-h]pteridin-6(5H)-one,(S)-6a-ethyl-5-methyl-2-(2-phenylpyridin-3-yl)-6a,7,9,10-tetrahydro-[1,4]oxazino[3,4-h]pteridin-6(5H)-one,(R)-7-ethyl-2-(2-(4-fluorophenyl)-1H-imidazol-1-yl)-5-methyl-8-(1-methyl-1H-pyrazol-3-yl)-7,8-dihydropteridin-6(5H)-one,(R)-7-ethyl-5-methyl-8-(1-methyl-1H-pyrazol-4-yl)-2-(2-phenyl-1H-imidazol-1-yl)-7,8-dihydropteridin-6(5H)-one,(S)-2-(5-(2,4-difluorophenyl)-1H-pyrazol-4-yl)-6a-ethyl-5-methyl-6a,7,9,10-tetrahydro-[1,4]oxazino[3,4-h]pteridin-6(5H)-one,(R)-7-ethyl-5-methyl-8-(1-methyl-1-pyrazol-4-yl)-2-(1-methyl-3-(thiazol-2-yl)-1H-pyrazol-4-yl)-7,8-dihydropteridin-6(5H)-one,(R)-2-(3-(2,4-difluorophenyl)-1H-pyrazol-4-yl)-7-ethyl-5-methyl-8-(1-methyl-1H-pyrazol-4-yl)-7,8-dihydropteridin-6(5H)-one,(R)-7-ethyl-5-methyl-8-(1-methyl-1H-pyrazol-3-yl)-2-(1-methyl ...

Method and apparatus for replacing identity certificate in blockchain network, storage medium, and computer device

A method for replacing an identity certificate in a blockchain network includes a service subnet, a consensus subnet, and a routing layer used for isolating the service subnet from the consensus subnet. The method includes: receiving a root certificate replacement notification transmitted by a certificate authentication center; obtaining a public key corresponding to the certificate authentication center; verifying the root certificate replacement notification by using the obtained public key; forwarding the root certificate replacement notification to a consensus node in the consensus subnet after the validation succeeds, so that the consensus node records the root certificate replacement notification into a latest data block after a consensus on the root certificate replacement notification is reached; and requesting, when the data block is received, the certificate authentication center to replace an identity certificate. A new identity certificate obtained through requesting is authenticated with a new root certificate of the certificate authentication center.

SUBSTITUTED QUINAZOLINES FOR INHIBITING KINASE ACTIVITY

Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described. 197.-. (canceled)98. A method of treating a patient diagnosed with non-small cell lung cancer (NSCLC) comprising administering to the patient in need thereof a therapeutically effective amount of a compound selected from the group consisting of N-(3-(2-((4-(4-(2-hydroxyethyl)piperazin-1-yl)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide , N-(3-(2-((2 ,3-difluoro-4-(4-(2-hydroxyethyl)piperazin-1-yl)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide , N-(3-(2-((2 ,3-difluoro-4-(4-methylpiperazin-1-yl)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide , N-(3-(2-((2 ,3-difluoro-4-(4-(2-hydroxy-2-methylpropyl)piperazin-1-yl)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide , N-(3-(2-((2 ,3-difluoro-4-(4-(2-methoxyethyl)piperazin-1-yl)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide , N-(3-(2-((4-(4-(2-methoxyethyl)piperazin-1-yl)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide , N-(3-(2-((3-fluoro-4-(4-(2-methoxyethyl)piperazin-1-yl)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide , N-(3-(2-((2-fluoro-4-(4-(2-hydroxyethyl)piperazin-1-yl)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide , N-(3-(2-((6-(4-methylpiperazin-1-yl)pyridin-3-yl)amino)quinazolin-8-yl)phenyl)acrylamide , N-(3-(2-((4-(4-methylpiperazin-1-yl)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide and pharmaceutically acceptable salts thereof.99. The method of claim 98 , wherein the patient is diagnosed with metastatic NSCLC.100. The method of claim 98 , wherein the patient is treatment naïve.101. The method of claim 98 , wherein the patient has progressed on or after epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) therapy.102. The method of claim 98 , wherein the patient has one or more mutations in the EGFR gene.103. The method of claim 102 , wherein the one or more mutations are selected from the group consisting of EGFR del E746-A750 claim 102 , EGFR del E747-E749/A750P claim 102 , ...

Measuring reception quality of a differential Manchester encoded signal

A receiver includes an interface and a processor. The interface is configured to receive a signal including symbols carrying bit values in respective symbol intervals, and to convert the received signal into a serial sequence of digital samples, the received signal being modulated using a Differential Manchester Encoding (DME) scheme that (i) represents a first bit value by a first symbol type having a level transition in the corresponding symbol interval and (ii) represents a second bit value by a second symbol type having a constant level in the corresponding symbol interval. The processor is configured to derive an error signal from the digital samples, and to produce a quality measure of the received signal based on the derived error signal.

Interactive method, apparatus, and system in live room

The present disclosure discloses an interactive method and apparatus in a live room. The method includes: receiving, from a live backstage, a live video stream sent by a first client; displaying a live interface on a display screen according to the live video stream; receiving, from the live backstage, an interactive video sent by a second client, the second client and the first client belong to a same live room, and the interactive video being a video whose video duration is less than a preset threshold; and playing, in picture-in-picture mode (PIP), the interactive video on a PIP area of the live interface.

Method And Device For Media Content-Based Interaction And Medium

Provided are a method and a device for media content-based interaction, and a computer readable medium. The method includes: receiving an acquisition operation for dynamic of a user on a media page; acquiring dynamic data of the user and dynamic data of a friend associated with the user in response to the acquisition operation for dynamic, where the dynamic data includes marking on a piece of media content and interaction information associated with the marked media content; and displaying on a display page for dynamic based on the dynamic data of the user and the dynamic data of the friend.

Cleaning Module, Sample Analyzer with Cleaning Module and Cleaning method

A cleaning module, a sample analyzer with the cleaning module and a cleaning method. Wherein, the cleaning module may include a disk body assembly and a cleaning assembly. The disk body assembly may include a disk body, the cleaning assembly and the disk body may move relatively, and the disk body and the cleaning assembly complete extraction of waste fluid and cleaning on a path of moving relatively. 1. A cleaning module , comprising:a disk body assembly, the disk body assembly comprising a disk body;a cleaning assembly, the cleaning assembly being provided with a waste fluid extracting station and a cleaning station, the waste fluid extracting station being an operating position when the cleaning assembly extracts waste fluid, and the cleaning station being an operation position when the cleaning assembly cleans; andthe cleaning assembly and the disk body being able to move relatively, and the cleaning station and the waste fluid extracting station being located inside the disk body.2. The cleaning module as claimed in claim 1 , wherein claim 1 , the disk body is provided with a plurality of reaction vessel placing portions claim 1 , the waste fluid extracting station is located inside one of the plurality of the reaction vessel placing portions claim 1 , and the cleaning station is located under the plurality of reaction vessel placing portions.3. The cleaning module as claimed in claim 2 , wherein claim 2 , the cleaning assembly further comprises a cleaning pool claim 2 , the cleaning station is located in the cleaning pool claim 2 , and the cleaning pool is located under the plurality of reaction vessel placing portions.4. The cleaning module as claimed in claim 3 , wherein claim 3 , a side wall of the cleaning pool is provided with a fluid inlet claim 3 , and a bottom wall of the cleaning pool is provided with a fluid outlet.5. The cleaning module as claimed in claim 1 , wherein claim 1 , the cleaning assembly is able to move along a vertical direction to ...

CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS

Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described. 2. The compound or pharmaceutically acceptable salt of any one of claim 1 , wherein G iscyano claim 1 , halo claim 1 , optionally substituted alkoxy claim 1 , optionally substituted cycloalkyloxy claim 1 , optionally substituted aryloxy claim 1 , optionally substituted heteroaryloxy claim 1 , optionally substituted heterocycloalkyloxy claim 1 , optionally substituted alkyl claim 1 , optionally substituted cycloalkyl claim 1 , optionally substituted aryl claim 1 , optionally substituted heteroaryl claim 1 , optionally substituted heterocycloalkyl claim 1 , optionally substituted amino claim 1 , optionally substituted acyl claim 1 , optionally substituted alkoxycarbonyl claim 1 , optionally substituted aminocarbonyl claim 1 , optionally substituted aminosulfonyl.3. The compound or pharmaceutically acceptable salt of claim 2 , wherein G is halo or optionally substituted alkoxy.4. The compound or pharmaceutically acceptable salt of claim 2 , wherein G is optionally substituted aryl claim 2 , optionally substituted heteroaryl claim 2 , or optionally substituted heterocycloalkyl.9. The compound or pharmaceutically acceptable salt of any one of - claim 2 , wherein L is —[(CRR)—NR—(CRR)]—.10. The compound or pharmaceutically acceptable salt of claim 9 , wherein L is —O— claim 9 , —CH— claim 9 , —NH— claim 9 , —S— claim 9 , —CO— claim 9 , —CO— claim 9 , —CONH— claim 9 , SO— claim 9 , or —SONH—.11. The compound or pharmaceutically acceptable salt of claim 10 , wherein L is —NH—.12. The compound or pharmaceutically acceptable salt of any one of - claim 10 , wherein each Z is independently hydrogen claim 10 , cyano claim 10 , halo claim 10 , optionally substituted amino claim 10 , optionally substituted alkoxy claim 10 , optionally substituted cycloalkyloxy claim 10 , optionally substituted aryloxy claim 10 , optionally substituted heteroaryloxy claim 10 , ...

Precursors for Lithium Transition Metal Oxide Cathode Materials for Rechargeable Batteries

A particulate precursor compound for manufacturing a lithium transition metal (M)-oxide powder usable as an active positive electrode material in lithium-ion batteries, wherein (M) is NiMnCoA, A being a dopant, wherein 0.33≦x≦0.60, 0.20≦y≦0.33, and 0.20≦z≦0.33, v≦0.05, and x+y+z+v=1, the precursor having a specific surface area PBET in m/g, a tapped density PTD in g/cm, a median particle size PD50 in μm, and wherein (I). 15-. (canceled)8. The precursor compound of claim 6 , wherein v=0 claim 6 , the compound having a PTD<2 g/cm.9. The precursor compound of claim 6 , wherein the precursor is a hydroxide M-OH or an oxyhydroxide M-OOH compound. The invention is related to particulate precursor compounds for manufacturing a lithium transition metal (M)-oxide powder usable as an active positive electrode material in lithium-ion batteries. More in particular, the precursors may be hydroxide or oxyhydroxide compounds having physical characteristics such as tapped density, specific surface area and median particle size that are related by a mathematical formula to the Ni content of the precursor.Due to their high energy density, rechargeable lithium and lithium-ion batteries can be used in a variety of portable electronics applications, such as cellular phones, laptop computers, digital cameras and video cameras.Commercially available lithium-ion batteries typically consist of graphite-based anode and LiCoO-based cathode materials. However, LiCoO-based cathode materials are expensive and typically have a relatively low capacity of approximately 150 mAh/g.Alternatives to LiCoO-based cathode materials include LNMCO type cathode materials. LNMCO means lithium-nickel-manganese-cobalt-oxides. The composition is LiMO2 or LiMOwhere M=NiCoMnA(which is more generally referred to as “NMC”, A being one or more dopants). LNMCO has a similar layered crystal structure as LiCoO(space group r-3m). The advantage of LNMCO cathodes is the much lower raw material price of the composition M ...

CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS

Chemical entities based on quinoxaline that are kinase inhibitors are described. Specifically quinoxaline derivatives of Formula I, containing a diarylamide or diarylurea substructure that inhibit Braf mutant kinase activity, pharmaceutical compositions containing the inhibitor compounds and methods of treatment of cancer comprising administering an effective amount of the Braf inhibitor compound are described. 177.-. (canceled)79. The method of claim 78 , wherein the mutant B-raf comprises a mutation in codon 600.80. The method of claim 78 , wherein the mutant B-raf is B-raf V600E mutant or B-Raf V600E/T5291.81. The method of claim 78 , wherein Ris optionally substituted aryl claim 78 , optionally substituted heterocycloalkyl claim 78 , or optionally substituted heteroaryl.82. The method of claim 78 , wherein R claim 78 , R claim 78 , R claim 78 , and Rare independently hydrogen claim 78 , halo claim 78 , cyano claim 78 , optionally substituted alkoxy claim 78 , or optionally substituted alkyl.83. The method of claim 78 , wherein Ris hydrogen or halo.84. The method of claim 78 , wherein Rand Rare hydrogen.85. The method of claim 78 , wherein Ris fluoro.86. The method of claim 78 , wherein Ris optionally substituted lower alkyl claim 78 , optionally substituted aryl claim 78 , or optionally substituted heteroaryl.87. The method of claim 78 , wherein Ris —COR claim 78 , —COR claim 78 , —CONRR claim 78 , —C(NR)NRR claim 78 , —C(NCN)NRR claim 78 , or —SONRR; wherein Ris optionally substituted alkyl claim 78 , optionally substituted cycloalkyl claim 78 , optionally substituted heterocycloalkyl claim 78 , optionally substituted aryl claim 78 , or optionally substituted heteroaryl; and Rand Rare independently hydrogen claim 78 , optionally substituted alkyl claim 78 , optionally substituted cycloalkyl claim 78 , or optionally substituted heterocycloalkyl.88. The method of claim 87 , wherein Ris optionally substituted alkyl claim 87 , optionally substituted aryl claim 87 , ...

Chemiluminescence Detector, Consumable Box Automatic Transmission Device and Transmission Method Thereof

The present disclosure provides a consumable box automatic transmission device. The consumable box automatic transmission device includes a consumable box storage mechanism, configured to load and store consumable boxes, and a consumable box lifting mechanism, located above the consumable box storage mechanism; the consumable box lifting mechanism is able to lift the consumable boxes; the consumable box storage mechanism and the consumable box lifting mechanism is able to respectively store and transmit the consumable boxes; the consumable box storage mechanism is able to transmit the consumable boxes to the bottom of the consumable box lifting mechanism; and the consumable box lifting mechanism receives the consumable boxes at a bottom and lifts the consumable boxes to a top layer of the consumable box lifting mechanism. In this way, parallel consumable box transmission can be achieved, and continuous consumable box conveyance is achieved, thereby reducing manual care or frequent manual operation. 1. A consumable box automatic transmission device , comprising:a consumable box storage mechanism, configured to load and store consumable boxes; anda consumable box lifting mechanism, located above the consumable box storage mechanism, wherein the consumable box lifting mechanism is able to lift the consumable boxes;wherein the consumable box storage mechanism and the consumable box lifting mechanism is able to respectively store and transmit the consumable boxes; the consumable box storage mechanism is able to transmit the consumable boxes to the bottom of the consumable box lifting mechanism; and the consumable box lifting mechanism receives the consumable boxes at a bottom and lifts the consumable boxes to a top layer of the consumable box lifting mechanism.2. The consumable box automatic transmission device as claimed in claim 1 , wherein the consumable box lifting mechanism comprises a lifting transmission structure; the lifting transmission structure can support ...

Computing device, computing apparatus and method of warp accumulation

The embodiments of the disclosure relate to a computing device, a computing apparatus, and a method of warp accumulation and relate to the field of computers. The computing device includes a storage unit and an accumulation computing unit coupled to the storage unit. The accumulation computing unit is configured to receive, from a vector processing unit coupled to the computing device, a first warp accumulation instruction, a plurality of first values corresponding to a warp lane number, and a first storage address; generate a current accumulation result based on the plurality of first values in response to the first warp accumulation instruction; and store the current accumulation result in the first storage address in the storage unit to be read by the vector processing unit. In this way, accumulation in a warp may be decoupled to dedicated hardware for processing, and overall accumulation performance may thus be significantly improved.

SLUDGE ANAEROBIC FERMENTATION TREATMENT METHOD WITH SIMULTANEOUSLY ENHANCED ACID PRODUCTION AND PHOSPHORUS REMOVAL

The present invention discloses a sludge anaerobic fermentation treatment method with simultaneously enhanced acid production and phosphorus removal. The method includes steps of: (1) adding waste activated sludge into an anaerobic reaction system, with a concentration of a total suspended solid (TSS) of 10000-15000 mg/L; (2) maintaining a pH value of the waste activated sludge at 10±0.1; adding powdery magnetite of 0.3-0.9g/gVS S. Compared with simple alkaline conditions, in the method of the present invention, an accumulation amount of short chain fatty acids (SCFAs) in a fermentation broth is increased by 20%, and a content of orthophosphoric acid is reduced by 10%. The method can further improve the enhancing effect by using sulfuric acid to modify the magnetite, the accumulation amount of SCFAs can be increased by 36.7% at most, and the content of phosphorus and refractory organic substances can be reduced by 32.4% and 40.4% at most, respectively. 1. A sludge anaerobic fermentation treatment method with simultaneously enhanced acid production and phosphorus removal , comprising the following steps:(1) adding waste activated sludge into an anaerobic reaction system, wherein a concentration of a total suspended solid TSS of the waste activated sludge is 10000-15000 mg/L, and a concentration of a volatile suspended solid VSS of the waste activated sludge is 6000-9000 mg/L; and(2) adjusting a pH value of the waste activated sludge to 10±0.1 with a sodium hydroxide solution; adding magnetite into the waste activated sludge with an addition amount of 0.3-0.9 g/gVSS; removing air in a reactor, then sealing the reactor, and performing anaerobic fermentation for 10-15 days under stirring, while always maintaining the pH value of the waste activated sludge at 10±0.1 during the stirring and the fermentation.2. The sludge anaerobic fermentation treatment method with simultaneously enhanced acid production and phosphorus removal according to claim 1 , wherein the waste ...

CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS

Chemical entities based on quinoxaline that are kinase inhibitors are described. Specifically quinoxaline derivatives of Formula I, containing a diarylamide or diarylurea substructure that inhibit Braf mutant kinase activity, pharmaceutical compositions containing the inhibitor compounds and methods of treatment of cancer comprising administering an effective amount of the Braf inhibitor compound are described. 126-. (canceled)28. The compound or pharmaceutically acceptable salt of claim 27 , wherein Rand Rare hydrogen.29. (canceled)30. The compound or pharmaceutically acceptable salt of claim 27 , wherein Ris optionally substituted aryl claim 27 , optionally substituted heterocycloalkyl claim 27 , or optionally substituted heteroaryl.31. The compound or pharmaceutically acceptable salt of claim 27 , wherein Ris optionally substituted morpholinyl claim 27 , optionally substituted piperazinyl claim 27 , optionally substituted pyrrolidinyl claim 27 , optionally substituted piperidinyl claim 27 , optionally substituted imidazolyl claim 27 , optionally substituted pyrazolyl claim 27 , or optionally substituted pyridyl.32. The compound or pharmaceutically acceptable salt of claim 27 , wherein R claim 27 , R claim 27 , R claim 27 , and Rare independently hydrogen claim 27 , halo claim 27 , cyano claim 27 , optionally substituted alkoxy claim 27 , or optionally substituted alkyl.33. (canceled)34. (canceled)35. The compound or pharmaceutically acceptable salt of claim 27 , wherein Ris fluoro.36. The compound or pharmaceutically acceptable salt of claim 27 , wherein Ris hydrogen or halo.3739-. (canceled)40. The compound or pharmaceutically acceptable salt of claim 27 , wherein Ris optionally substituted lower alkyl claim 27 , optionally substituted aryl claim 27 , or optionally substituted heteroaryl.41. (canceled)42. (canceled)43. The compound or pharmaceutically acceptable salt of claim 27 , wherein Ris —COR claim 27 , —COR claim 27 , —CONRR claim 27 , —C(NR)NRR claim 27 , ...

METHOD FOR COMPUTING, COMPUTING DEVICE, AND COMPUTER-READABLE STORAGE MEDIUM

A method for computing, a computing device, and a computer-readable storage medium are provided. The method includes determining a first pixel block in a cache. The first pixel block is composed of a 2m row×2n column pixel matrix and includes original pixel data and pixel data related to the original pixel data. The first pixel block is read from the cache. At least part of the pixel data related to the original pixel data is used for padding related to the original pixel data. The original pixel data includes pixel data from the (n+1)column to the 2ncolumn in the (m+1)row to the 2mrow in the 2m row×2 n column pixel matrix. When reading data from the cache, pixel data that needs to be obtained after insert-zero and padding operations on the original pixel data in back propagation can be read at one time. 1. A method for computing , comprising:determining a first pixel block in a cache, wherein the first pixel block is composed of a 2m row×2n column pixel matrix and comprises original pixel data and pixel data related to the original pixel data, where m and n are positive integers; andreading the first pixel block from the cache,{'sup': th', 'th', 'th', 'th, 'wherein at least part of the pixel data related to the original pixel data is used for padding related to the original pixel data, and the original pixel data comprises pixel data from an (n+1)column to a 2ncolumn in an (m+1)row to a 2mrow in the 2m row×2n column pixel matrix.'}2. The method according to claim 1 , further comprising:determining p rows from 2m rows of the 2m row×2n column pixel matrix based on a coordinate in a vertical direction indicated by a padding configuration related to the original pixel data to obtain a p row×2n column pixel matrix;determining q columns from 2n columns of the determined p row×2n column pixel matrix based on a coordinate in a horizontal direction indicated by the padding configuration to obtain a p row×q column pixel matrix, where p and q are positive integers;performing ...

TIME-OF-FLIGHT-BASED DISTANCE MEASUREMENT SYSTEM AND METHOD

A time of flight (TOF)-based distance measurement system and method with a time code are provided. The system includes: an emitter, configured to emit an optical signal pulse train with a time code; a collector, configured to collect photons in the optical signal pulse train reflected by an object; and a processing circuit, connected to the emitter and the collector, and configured to count the photons to form a frame-period single-photon counting timing train, and draw a histogram based on the time code and the frame-period single-photon counting timing train. In the system and method of this application, the emitter is allowed to emit a pulse train based on a pulse period far shorter than a maximum TOF corresponding to a maximum measurement distance, so that a frame rate may be improved significantly. 1. A time of flight (TOF)-based distance measurement system , comprising:an emitter, configured to emit an optical signal pulse train with a time code;a collector, configured to collect photons in the optical signal pulse train reflected by an object; anda processing circuit, connected to the emitter and the collector, and configured to count the photons to form a frame-period single-photon counting timing train, and draw a histogram based on the time code and the frame-period single-photon counting timing train.2. The system according to claim 1 , wherein a time interval between adjacent pulse trains is less than a maximum TOF corresponding to a maximum measurement distance.3. The system according to claim 1 , wherein the collector comprises a single-photon avalanche photodiode (SPAD).4. The system according to claim 1 , wherein:the time code is a regular time code [Δt, 2Δt, 3Δt, . . . , (n−1)Δt], wherein Δt is a pulse period, and n is a quantity of pulses included in the optical signal pulse train; andthe histogram is drawn by: using a time unit in the histogram as a start unit; accumulating photon counts in all time units subsequently spaced from the start unit by ...

TIME-OF-FLIGHT-BASED DISTANCE MEASUREMENT SYSTEM AND METHOD

This application provides a time of flight (TOF)-based distance measurement system with adjustable histograms, including: an emitter, configured to emit a pulsed beam; a collector, configured to collect a photon in the pulsed beam reflected by an object and form a photonic signal; and a processing circuit, connected to the emitter and the collector, and including a TDC circuit and a histogram circuit. The TDC circuit is configured to receive the photonic signal, calculate a time interval of the photonic signal, and convert the time interval into a time code. The histogram circuit counts photons on a corresponding internal time unit based on the time code, and collects statistics on photon counts in all time units after a plurality of measurements to draw a histogram. An address of the time unit can be dynamically adjusted to dynamically adjust a time resolution and/or a time range width of the histogram. 1. A time of flight (TOF)-based distance measurement system , comprising:an emitter, configured to emit a pulsed beam;a collector configured to collect a photon in the pulsed beam reflected by an object to generate a photonic signal; anda processing circuit, connected to the emitter and the collector, and comprising a time-to-digital converter (TDC) circuit and a histogram circuit, wherein the TDC circuit is configured to receive the photonic signal, to calculate a time interval of the photonic signal and to convert the time interval into a time code, and the histogram circuit counts photons in a corresponding time unit based on the time code and collects statistics on photon counts in time units after a plurality of measurements to draw a histogram, whereinan address of the time unit is dynamically adjusted to dynamically adjust a time resolution and/or a time range width of the histogram.2. The TOF-based distance measurement system according to claim 1 , further comprising:determining a time corresponding to a pulse waveform in the histogram; anddetermining a TOF ...

METHOD AND DEVICE FOR PROCESSING USER GENERATED CONTENT

Described are a method and a device for processing a user generated content (UGC). The method includes: providing an interface; receiving a calendar entry establishment request of a user, and establishing a calendar entry on the interface; searching for a UGC matching the calendar entry on the interface, and displaying the UGC on the interface; receiving a selection command for selecting the UGC from the interface, and associating the UGC selected with the calendar entry; displaying the calendar entry and information of the UGC associated with the calendar entry on the interface. The device correspondingly includes: a calendar entry establishing module, a UGC searching module, an associating module, and a calendar entry displaying module 1. A method for processing a user generated content (UGC) , comprising:at a device having one or more processors and a memory for storing one or more programs to be executed by the one or more processors;providing an interface;receiving a calendar entry establishment request of a user, and establishing a calendar entry on the interface;searching for a UGC matching the calendar entry, and displaying the UGC on the interface;receiving a selection command for selecting the UGC from the interface, and associating the UGC selected with the calendar entry; anddisplaying the calendar entry and information of the UGC associated with the calendar entry on the interface.2. The method according to claim 1 , wherein the step of receiving a calendar entry establishment request of a user claim 1 , and establishing a calendar entry on the interface claim 1 , comprises:noticing the user to input time information and textual description, recording the time information and the textual description input by the user, and generating the calendar entry with the textual description and the time information;the step of searching for a UGC matching the calendar entry, comprises:searching for a UGC which matches a preset matching rule with the time ...

INFORMATION SHARING METHOD, APPARATUS AND COMPUTER DEVICE

Described is an information sharing method and apparatus, which are directed to information published by a user in a social network. For information published by a user in a social network, when a sharing instruction of the user is received, a selection box comprising one or more sharing targets is displayed for the user, each sharing target has its corresponding social network, and the social network corresponding to the sharing target includes a social network which published the information; when a submission instruction of the user is received, the information is sent to a sharing target selected by the user from the selection box. By using the present method, the spread of information can be accelerated, and the implementation is simple and convenient. 1. An information sharing method , comprising:receiving a sharing instruction sent by a client user;displaying a selection box comprising one or more sharing targets; each sharing target corresponding to one social network, and social networks, corresponding to the one or more sharing targets, comprising a social network where preset information is published;receiving a selection of one sharing target from the selection box; andsending the preset information to the sharing target selected from the selection box when receiving a submission instruction from the client user,2. The method of claim 1 , wherein each sharing target comprises:friends of the user in a first social network;a personal space of the user in a second social network; or/anda personal space of the user in a third social network.3. The method of claim 2 , further comprising:displaying a search link in the selection box;if the sharing target selected by the client user is the friends of the client user in the first social network, the sending the preset information to the sharing target comprising:converting the search link into a search box when the client user clicks the search link;displaying object names of a first group of users who have ...

CHEMILUMINESCENCE ENHANCER AND CHEMILUMINESCENCE IMMUNODETECTION KIT

Disclosed a chemiluminescence enhancer and a chemiluminescence immunodetection kit. The chemiluminescence enhancer is specifically a betaine and can be used for enhancing the luminance of a luminescent acridine substance. The chemiluminescence immunodetection kit comprising the chemiluminescence enhancer and a luminescent acridine substance features greatly enhanced luminescence signals and high detection sensibility, and can be widely applied to fields such as clinical diagnoses, scientific research, and sanitation analysis. 1. A chemiluminescence enhancer , for enhancing a luminescence intensity of an acridine luminescent substance , comprising a betaine compound.8. A chemiluminescence immunoassay kit comprising a chemiluminescence enhancer of and an acridine luminescent substance.9. The chemiluminescence immunoassay kit according to claim 8 , wherein the acridine luminescent substance is an acridinium ester or an acridine salt.10. The chemiluminescence immunoassay kit according to claim 8 , further comprising a chemiluminescence pre-trigger solution and trigger solution claim 8 , wherein the chemiluminescence pre-trigger solution comprises HNOand HOsolutions claim 8 , and the trigger solution comprises a NaOH solution. The present disclosure relates to the field of analytical detection technology, and more particularly relates to a chemiluminescence enhancer and a chemiluminescence immunoassay kit.Chemiluminescence immunoassay (CLIA) is a novel labeling immunoassay technique that combines a chemiluminescent or bioluminescent system with an immune response for the detection of trace antigens or antibodies. Chemiluminescence immunoassay is currently the most mainstream immunoassay technology in the world. It has the advantages of high sensitivity, wide detection range, short reaction time, fully automatic operation, good reproducibility, no pollution, and the like. It is an ultra-high sensitive micro-detection technology developed after radioimmunoassay, enzyme ...

INTERACTING METHOD, APPARATUS AND SERVER BASED ON IMAGE

An interactive method, apparatus based on an image and a server are provided according to embodiments of the present invention. The method includes: recognizing a face region in an image; generating a face box corresponding to the face region; generating a label box corresponding to the face box; and representing label information corresponding to the face region in the label box by performing one of the following modes: obtaining the label information corresponding to the face region from a server, representing the label information obtained from the server in the label box; and receiving the label information corresponding to the face region inputted by a user, representing the label information inputted by the user in the label box. Thus, based on the label information provided by the server or the user, information associated with a circled region is customized (e.g., reviews information), and is further pushed to an associated friend. Thus, interaction between a user pushing the face region and the associated friend is improved. 1. An interactive method based on an image , comprising:recognizing a face region in an image;generating a face box corresponding to the face region;generating a label box corresponding to the face box; andrepresenting label information corresponding to the face region in the label box by performing one of the following modes: obtaining the label information corresponding to the face region from a server, representing the label information obtained from the server in the label box; andreceiving the label information corresponding to the face region inputted by a user, representing the label information inputted by the user in the label box.2. The method of claim 1 , wherein the face region is recognized by performing one of the following algorithms:a Principal Component Analysis (PCA), an Independent Component Analysis (ICA), an Isometric Feature Mapping (ISOMAP), a Kernel Principal Components Analysis (KPCA), a Linear Principal ...

COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR

Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases. 120-. (canceled)22. The compound of claim 21 , wherein Ris hydrogen.23. The compound of claim 21 , wherein Ris halogen.24. The compound of claim 21 , wherein Ris optionally substituted phenyl.25. The compound of claim 21 , wherein Ris phenyl substituted with one or more substituents selected from the group consisting of fluoro claim 21 , lower alkyl claim 21 , fluoro substituted lower alkyl claim 21 , lower alkoxy claim 21 , fluoro substituted lower alkoxy claim 21 , lower alkylthio claim 21 , and fluoro substituted lower alkylthio.26. The compound of claim 21 , wherein Ris phenyl substituted with one or more fluoro.27. The compound of claim 21 , wherein each Ris optionally substituted lower alkyl.28. The compound of claim 21 , wherein each Ris optionally substituted heteroaryl.29. The compound of claim 21 , wherein Ar is a monocyclic heteroaryl containing 5 to 6 atoms.30. A pharmaceutical composition comprising a compound of and a pharmaceutically acceptable carrier or excipient.31. A pharmaceutical composition comprising a compound of and another therapeutic agent.32. A method for treating a subject suffering from melanoma claim 21 , thyroid cancer or colorectal cancer claim 21 , said method comprising administering to the subject an effective amount of a compound of .33. The method of claim 32 , wherein the melanoma is melanoma having a mutation encoding a V600E amino acid substitution. This application is a continuation application of U.S. application Ser. No. 13/866,353, filed Apr. 19, 2013, which is a continuation application of U.S. application Ser. No. 12/669,450, filed Jan. 15, 2010, which application is a National Phase application under 35 U.S.C. §371 of PCT/US2008/070124, filed Jul. 16, 2008, which claims the benefit under 35 U.S.C. §119(e) from U.S. Application No. 60/959,907 ...

CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS

Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described. 8. (canceled)9. (canceled)10. The compound or pharmaceutically acceptable salt of claim 1 , wherein m is 1 claim 1 , 2 claim 1 , or 3; and at least one Q is E.11. The compound or pharmaceutically acceptable salt of claim 1 , wherein n is 1 and Z is optionally substituted heterocycloalkyl.12. The compound or pharmaceutically acceptable salt of claim 11 , wherein Z is optionally substituted piperazinyl.13. (canceled)17. The compound or pharmaceutically acceptable salt of claim 16 , wherein Ris hydrogen claim 16 , cyano claim 16 , halo claim 16 , hydroxy claim 16 , —CONH claim 16 , optionally substituted alkoxy claim 16 , or optionally substituted cycloalkyloxy.18. (canceled)19. The compound or pharmaceutically acceptable salt of claim 16 , wherein R claim 16 , R claim 16 , and Rare independently hydrogen claim 16 , cyano claim 16 , halo claim 16 , hydroxy claim 16 , carboxy claim 16 , optionally substituted alkoxy claim 16 , optionally substituted lower alkyl claim 16 , optionally substituted heterocycloalkyl claim 16 , optionally substituted aryl claim 16 , optionally substituted heteroaryl claim 16 , optionally substituted amino claim 16 , optionally substituted acyl claim 16 , optionally substituted alkoxycarbonyl claim 16 , or optionally substituted aminocarbonyl.20. (canceled)21. The compound or pharmaceutically acceptable salt of claim 19 , wherein Rand Rare hydrogen claim 19 , and Ris optionally substituted morpholinyl claim 19 , optionally substituted piperazinyl claim 19 , optionally substituted pyrrolidinyl claim 19 , optionally substituted piperidinyl claim 19 , optionally substituted azetidinyl claim 19 , or substituted amino.22. (canceled)23. The compound or pharmaceutically acceptable salt of claim 19 , wherein Rand Rare hydrogen claim 19 , and Ris optionally substituted morpholinyl claim 19 , optionally substituted piperazinyl ...

Sandwich type fingerprint recognition device

The present invention discloses sandwich type fingerprint recognition devices, one embodiment of the sandwich type fingerprint recognition device includes a first transparent layer, a spatial filter layer with multiple through holes, a second transparent layer and an optical sensor. Another embodiment of the sandwich type fingerprint recognition device includes a first transparent layer, a spatial filter layer with multiple through holes and an optical sensor. With the implementation of the present invention, complex production process or equipment are not required for producing fingerprint recognition device that reduce costs; the size of the fingerprint recognition device is reduced; a variety of thickness choices for the first transparent layer or second transparent layer and a variety of colors can be used and more applications are thus possible; and the contrast of fingerprint signal is enhanced to enable clarifying fingerprint features and characteristics and thus recognition accuracy of fingerprints.

COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR

Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases. 19. The compound according to wherein Ris optionally substituted Calkyl claim 18 , optionally substituted cycloalkyl claim 18 , optionally substituted heterocycloalkyl claim 18 , optionally substituted aryl claim 18 , optionally substituted heteroaryl claim 18 , or substituted methyl claim 18 , wherein methyl is substituted with optionally substituted cycloalkyl claim 18 , optionally substituted heterocycloalkyl claim 18 , optionally substituted aryl claim 18 , or optionally substituted heteroaryl.20. The compound of claim 19 , wherein Ris other than hydrogen.2139.-. (canceled) This application is a continuation of U.S. application Ser. No. 12/906,980 filed Oct. 18, 2010, which is a divisional of U.S. application Ser. No. 11/473,347 filed Jun. 21, 2006, now issued as U.S. Pat. No. 7,836,288, which claims the benefit under 35 U.S.C. §119(e) of U.S. Provisional Application No. 60/692,960, filed Jun. 22, 2005, and U.S. Provisional Application No. 60/731,528, filed Oct. 28, 2005, which are incorporated herein by reference in their entireties and for all purposes.The present invention relates to kinases and compounds which modulate kinases, and uses therefor. Particular embodiments contemplate disease indications which are amenable to treatment by modulation of kinase activity by the compounds of the present invention.The information provided herein is intended solely to assist the understanding of the reader. None of the information provided nor references cited is admitted to be prior art to the present invention. Each of the references cited herein is incorporated in its entirety.Receptor protein kinases regulate key signal transduction cascades that control or are involved in the control of a plethora of physiological functions including cellular growth and proliferation, cell ...

DATA PROCESSING METHOD AND APPARATUS IN BLOCKCHAIN NETWORK, STORAGE MEDIUM, AND COMPUTER DEVICE

A blockchain network includes a service sub-network, a consensus sub-network, and a routing layer configured to isolate the service sub-network from the consensus sub-network. A data processing method in the blockchain network includes: receiving a data processing request transmitted by a service node in the service sub-network; performing identity verification on the service node according to the data processing request; obtaining a running load of each consensus node in the consensus sub-network when the verification succeeds; determining, from the consensus sub-network according to the running load, a target consensus node configured to process the data processing request; and forwarding the data processing request to the target consensus node, and performing corresponding data processing on the data processing request by using the target consensus node. 1. A data processing method in a blockchain network , the blockchain network comprising a service sub-network , a consensus sub-network , and a routing layer configured to isolate the service sub-network from the consensus sub-network , and the method being performed by a computer device and comprising:receiving a data processing request transmitted by a service node in the service sub-network;performing identity verification on the service node according to the data processing request;obtaining a running load of each consensus node in the consensus sub-network when the verification succeeds;determining, from the consensus sub-network according to the running load, a target consensus node configured to process the data processing request;forwarding the data processing request to the target consensus node; andperforming corresponding data processing on the data processing request by using the target consensus node.2. The method according to claim 1 , wherein the data processing request is obtained by using a private key signature of the service node claim 1 , and the performing identity verification comprises: ...

SYSTEMS AND METHODS FOR MULTIMEDIA PROCESSING

Systems and methods are provided for multimedia processing. For example, an encoded file is acquired; the encoded file is parsed to obtain application-indication information and watermark-indication information associated with the encoded file; a multimedia-recording application associated with the application-indication information is called; watermark information is generated based on at least the watermark-indication information; the watermark information displayed on a recording interface of the multimedia-recording application; and in response to multimedia information being generated on the recording interface of the multimedia-recording application, the watermark information and the multimedia information is integrated. 1. A method for multimedia processing , the method comprising:acquiring an encoded file;parsing the encoded file to obtain application-indication information and watermark-indication information associated with the encoded file;calling a multimedia-recording application associated with the application-indication information;generating watermark information based on at least the watermark-indication information;displaying the watermark information on a recording interface of the multimedia-recording application; andin response to multimedia information being generated on the recording interface of the multimedia-recording application, integrating the watermark information and the multimedia information.2. The method of claim 1 , wherein:the encoded file comprises a two-dimensional barcode;the application-indication information comprises: address information associated with the multimedia-recording application and control information for calling the multimedia-recording application; andthe watermark-indication information comprises: topic information and identification information of a watermark template.3. The method of claim 2 , further comprising:acquiring configuration information of a current version of a client;determining whether the ...

POSITIVE ELECTRODE FOR LITHIUM ION BATTERY

A positive electrode composition for a rechargeable battery, the composition comprising a first and a second powderous lithium metal oxide, the first lithium metal oxide comprising either one or more of Ni, Mn and Co, the second lithium metal oxide powder having either: 114-. (canceled)15. A positive electrode composition for a rechargeable battery , the composition comprising a first and a second powderous lithium metal oxide , the first lithium metal oxide comprising either one or more of Ni , Mn and Co , the second lithium metal oxide powder having the formula LiWMO , M being a metal having a valence state of +2 or +3 , with 0 Подробнее

Page processing method, apparatus, and system

A page processing method, an apparatus, and a system are provided. The method includes: generating a parsing policy table according to a page attribute or a client attribute or both received from a client browser, where the parsing policy table is used to determine a parsing manner for a page that a user requests to access, and the parsing manner includes parsing on a web server or parsing on the client browser or both; determining, according to the parsing policy table, the parsing manner for the page that the user requests to access; and parsing, according to the parsing manner, the page that the user requests to access. According to the embodiments of the present invention, a parsing policy table is generated, so that different parsing manners may be selected according to an actual network or a service situation, which achieves flexible page processing and improves page processing efficiency.

COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR

Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases. 111-. (canceled)13. The method of claim 12 , wherein Ris hydrogen.14. The method of claim 12 , wherein Ris halogen.15. The method of claim 12 , wherein Ris optionally substituted phenyl.16. The method of claim 12 , wherein Ris phenyl substituted with one or more substituents selected from the group consisting of fluoro claim 12 , lower alkyl claim 12 , fluoro substituted lower alkyl claim 12 , lower alkoxy claim 12 , fluoro substituted lower alkoxy claim 12 , lower alkylthio claim 12 , and fluoro substituted lower alkylthio.17. The method of claim 12 , wherein Ris phenyl substituted with one or more fluoro.18. The method of claim 12 , wherein one of the Rsubstituents is lower alkyl containing 1-4 carbon atoms.19. The method of claim 12 , wherein one of the Rsubstituents is optionally substituted heteroaryl.20. The method of claim 12 , further comprising administering a chemotherapeutic agent in combination with the compound of formula (Ia).21. The method of claim 17 , further comprising administering a chemotherapeutic agent in combination with the compound of formula (Ia) claim 17 , and wherein the chemotherapeutic agent is a kinase inhibitor.22. The method of claim 18 , further comprising administering a chemotherapeutic agent in combination with the compound of formula (Ia) claim 18 , and wherein the chemotherapeutic agent is a kinase inhibitor.23. The method of claim 19 , further comprising administering a chemotherapeutic agent in combination with the compound of formula (Ia) claim 19 , and wherein the chemotherapeutic agent is a kinase inhibitor.24. The method of claim 21 , wherein the subject has melanoma.25. The method of claim 21 , wherein the melanoma is melanoma having a B-Raf V600E mutation.27. The method of claim 26 , wherein Ris hydrogen.28. The method of claim 26 , wherein ...

Smart Ultrasonic Stack And Method Of Controlling Ultrasonic System Having A Smart Ultrasonic Stack

An ultrasonic system has an ultrasonic stack excited by a power supply. The ultrasonic stack has a plurality of components, including an ultrasonic converter, a booster and an ultrasonic horn. A method of controlling the ultrasonic system with the power supply includes upon replacing any of the components of the ultrasonic stack with a replacement component, inputting an amplitude parameter of the replacement component into the power supply, determining with the power supply an amplitude of an AC excitation signal at which to excite the ultrasonic converter based on amplitude parameters of the components including the amplitude parameter of each replacement component. The power supply then sets the amplitude of the AC excitation signal at this determined amplitude. 1. A method of controlling an ultrasonic system , comprising:providing the ultrasonic system with a smart ultrasonic stack having a plurality of smart ultrasonic stack components including at least a smart ultrasonic converter and at least one smart ultrasonic stack component that is a passive ultrasonic component with each smart ultrasonic stack component having operational information about that smart ultrasonic stack component associated therewith by having that operational information stored at the smart ultrasonic stack component or in a database with an identifier that identifies the smart ultrasonic stack component with which the operational information is associated;having an ultrasonic power supply that excites the ultrasonic converter read the operational information associated with each smart ultrasonic stack component; andhaving the ultrasonic power supply operate the ultrasonic system based on the read operational information.2. The method of including each time a smart ultrasonic stack component is replaced with a replacement smart ultrasonic component claim 1 , reading with the ultrasonic power supply the operational information associated with the replacement smart ultrasonic component and ...

Certain chemical entities, compositions, and methods

Chemical entities based on quinoxaline that are kinase inhibitors are described. Specifically quinoxaline derivatives of Formula I, containing a diarylamide or diarylurea substructure that inhibit Braf mutant kinase activity, pharmaceutical compositions containing the inhibitor compounds and methods of treatment of cancer comprising administering an effective amount of the Braf inhibitor compound are described.

CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS

Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described. 2. (canceled)3. (canceled)57-. (canceled)9. The compound or salt of claim 8 , wherein R claim 8 , R claim 8 , R claim 8 , R claim 8 , R claim 8 , R claim 8 , R claim 8 , R claim 8 , R claim 8 , R claim 8 , R claim 8 , Rand Rare each independently selected from the group consisting of hydrogen claim 8 , cyano claim 8 , halo claim 8 , C-Calkyl claim 8 , C-Chaloalkyl claim 8 , C-Calkoxy claim 8 , 3- to 6-membered cycloalkyl claim 8 , aminocarbonyl and amino.1015.-. (canceled)16. The compound or salt of claim 8 , wherein Xis N and Lis selected from —O— claim 8 , —NH— and —C(O)NH—.1721-. (canceled)22. The compound or salt of claim 1 , wherein Lis a bond claim 1 , Lis a bond claim 1 , and m is 1 claim 1 , 2 claim 1 , 3 claim 1 , 4 claim 1 , or 5.2325-. (canceled)26. The compound or salt of claim 1 , wherein at least one Q is E.2730-. (canceled)31. The compound or salt of claim 1 , wherein Z is independently selected at each occurrence from cyano claim 1 , halo claim 1 , hydroxy claim 1 , azido claim 1 , nitro claim 1 , carboxy claim 1 , oxo claim 1 , sulfinyl claim 1 , sulfanyl claim 1 , sulfonyl claim 1 , optionally substituted alkoxy claim 1 , optionally substituted cycloalkyloxy claim 1 , optionally substituted aryloxy claim 1 , optionally substituted heteroaryloxy claim 1 , optionally substituted alkyl claim 1 , optionally substituted aryl claim 1 , optionally substituted heteroaryl claim 1 , optionally substituted heterocycloalkyl claim 1 , optionally substituted amino claim 1 , optionally substituted acyl claim 1 , optionally substituted alkoxycarbonyl claim 1 , optionally substituted aminocarbonyl claim 1 , optionally substituted aminosulfonyl claim 1 , and E.32. (canceled)33. (canceled)35. (canceled)3741-. (canceled)42. The compound or salt of claim 1 , wherein R claim 1 , R claim 1 , R claim 1 , R claim 1 , and Rare independently selected ...

Substituted quinazolines for inhibiting kinase activity

Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described.

METHOD AND DEVICE FOR SENDING MESSAGE TO GROUP USER(S) THROUGH MICROBLOG

The present invention discloses a method and device for sending a message to group user(s) through microblog, which can simply and rapidly send the message to the group user(s) through a symbol @. In the present invention, group(s) that a user has joined is inquired for the user when the user sends a message, and the message is able to be sent to the group user(s) in the manner of “@group”, instead of being sent to each group user in the manner of “@user nickname” for many times, which improves the efficiency of sending messages by group, and brings convenience to the user. 1. A method for sending a message to group user(s) through microblog , comprising:a service end parsing a received message, and when finding that the message contains “@group identifier”, acquiring the group identifier behind the “@”;the service end acquiring a list of group member user(s) by the group identifier, and pushing the message to each group member user in the list of group member user(s).2. The method of claim 1 , wherein each group member user in the list of group member user(s) acquires and displays the message through a page with the latest messages claim 1 , or a “message with @me” page claim 1 , or a “@group name” page.3. The method of claim 1 , wherein before the service end pushes the message to each group member user in the list of group member user(s) claim 1 , the method also comprises: the service end detecting whether a user sending the message is a group member user of a group indicated by the group identifier;if the user sending the message is a group member user of the group indicated by the group identifier, the service end will perform a processing of pushing the message;if the user sending the message is not a group member user of the group indicated by the group identifier, the service end will not perform the processing of pushing the message.4. The method of claim 1 , wherein the method also comprises:before a terminal end sends the message, it inquiring the ...

SECURITY CONTROL METHOD AND NETWORK DEVICE

Disclosed are a security control method and a network device. The method includes: a network device obtains confidential data generated by a software trusted platform module (TPM) running in the network device, where the confidential data includes permanent confidential data and refreshable confidential data, the permanent confidential data is data that cannot be updated during a startup process of the network device and the refreshable confidential data is data that can be updated during a startup process of the network device; the network device encrypts the permanent confidential data by using a white box algorithm and stores the permanent confidential data encrypted by using the white box algorithm and the refreshable confidential data in a storage unit whose address is hidden. 1. A security control method , comprising:obtaining, by a network device, confidential data, wherein the confidential data is generated by a software trusted platform module (TPM), the software TPM runs in the network device, and the confidential data comprises permanent confidential data and refreshable confidential data, wherein the permanent confidential data is data that cannot be updated during a startup process of the network device and the refreshable confidential data is data that can be updated during a startup process of the network device;encrypting, by the network device, the permanent confidential data by using a white box algorithm; andstoring, by the network device, the permanent confidential data encrypted by using the white box algorithm and the refreshable confidential data in a storage unit whose address is hidden.2. The method according to claim 1 , further comprising:performing, by the network device, when receiving an access operation on data that is stored in the storage unit whose address is hidden, policy control on the access operation by using an access control policy.3. The method according to claim 1 , further comprising:performing, by the network device, when ...