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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 11073. Отображено 100.
26-01-2012 дата публикации

Densensitizing dentifrice exhibiting dental tissue antibacterial agent uptake

Номер: US20120020900A1
Автор: Guofeng Xu, Ravi Subramanyam
Принадлежит: Colgate Palmolive Co

An oral composition exhibiting increased uptake by dental tissue of antibacterial compounds contained therein and eliminating or substantially reducing the discomfort and pain associated with dentinal hypersensitivity. The composition includes an orally acceptable vehicle for such composition, an effective therapeutic amount of an antibacterial compound, a mixture of anionic surfactant and amphoteric surfactant, the mixture having 0.1 wt. % to 2.0 wt. % anionic surfactant and 0.8 wt. % to 2.0 wt. % amphoteric surfactant, and a potassium ion releasable compound.

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Номер записи: 1
26-01-2012 дата публикации

Dual action dentifrice compositions to prevent hypersensitivity and promote remineralization

Номер: US20120021031A1
Автор: Lynette Zaidel, Michael Prencipe, Suman K. Chopra
Принадлежит: Colgate Palmolive Co

The invention encompasses combinations of bioactive glass composition and potassium salts that are useful in conjunction with delivery agent such as, for example, toothpastes, mouthwashes, and oral gels. In certain embodiments, the compositions of the invention form a rapid and continuous reaction with body fluids (e.g., saliva) to promote the immediate and long-tem release of Ca and P ions to produce a stable crystalline layer deposited onto and into the dentin tubules for the immediate and long term reduction of dentin hypersensitivity and tooth surface remineralization.

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Номер записи: 2
02-02-2012 дата публикации

Method and Composition for Reducing Exhaled Carbon Dioxide Emissions

Номер: US20120027827A1
Автор: Michael Lefenfeld, Tuhin Ganguly
Принадлежит: Individual

A method and composition for reducing the amount of carbon dioxide exhaled by a user by placing a composition comprising a delivery vehicle and a carbon dioxide sequestering agent into a user's mouth and allowing the carbon dioxide sequestering agent to react with the carbon dioxide present in the user's breath thereby reducing the amount of carbon dioxide exhaled by the user.

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Номер записи: 3
22-03-2012 дата публикации

Prophylaxis Paste Holder Dispenser with Multiple Prophylaxis Pastes

Номер: US20120067748A1
Автор: Jeanette Gail Vargo, Michael Schmitz, Michael Turner, Peter Jung, Rachel Barton
Принадлежит: Individual

A dental prophylaxis paste holder dispenser comprises a first prophylaxis paste and a second prophylaxis paste. The first prophylaxis paste has a first material. The second prophylaxis paste has a second material. The first material has a first material property and the second material has a second material property. The first material property differs from the second material property.

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Номер записи: 4
05-04-2012 дата публикации

Oral Care Compositions With Improved Flavor

Номер: US20120082628A1
Автор: Cathy Renee Schinaman, Christine Marie Cahen, John Christian Haught, Koti Tatachar Sreekishna, Wenzhu Zhao, Yakang Lin
Принадлежит: Procter and Gamble Co

Oral care compositions having improved taste, said compositions comprising: a carrier material; from about 0.001 to about 10%, by weight of the composition, of an oral care component selected from metal salts, antimicrobial agents, bad breath reduction agents, bleaching agents, surfactants, or a combination thereof; and from about 0.0001 to about 1%, by weight of the composition, of a TRPA1 agonist selected from vanillin esters; benzoate esters; hydroxybenzoate derivatives; methoxy benzoate derivatives; hydroxybutanedioate derivatives; benzamidobenzoate derivatives; methylpropanoate derivatives; phenyl acetate derivatives; hex-3-enoate derivatives; 2-(furan-2-ylmethylsulfanyl)-3-methylpyrazine; phenylmethoxymethylbenzene; (2R)-2-azaniumyl-3-[(2R)-2-azaniumyl-3-oxido-3-oxopropyl]disulfanylpropanoate; (3E)-2-hydroxy-4,8-dimethylnona-3,7-dienal; (2R)-2-azaniumyl-3-[(2S)-2-azaniumyl-3-oxido-3-oxopropyl]disulfanylpropanoate; (3Z)-3-butylidene-2-benzofuran-1-one; 3-methyl-N-(3-methylbutyl)butan-1-imine; 2-(furan-2-ylmethyldisulfanylmethyl)furan; and combinations thereof. Uses thereof and methods of improving the taste of an oral care composition.

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Номер записи: 5
05-04-2012 дата публикации

Oral Care Compositions With Improved Sweetness

Номер: US20120082630A1
Автор: Eva Schneiderman, John Christian Haught, Lowell Alan Sanker, Robert Leslie Swaine, Jr.
Принадлежит: Procter and Gamble Co

The present invention is directed to improved sweetener compositions and oral care compositions, especially those in the form of a toothpaste or oral/dental rinse, comprising the same. The sweetener composition comprises a combination of saccharin, sucralose and a rebaudioside, or sweeteners of similar sucrose equivalence and type, preferably in a ratio of about 1:about 1:about 2. The sweetener composition of the invention was found to significantly improve the taste profile, long lasting freshness and clean feel of oral care compositions and to deliver an in-use sweetness that was more natural and pleasant than artificial sweeteners alone.

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Номер записи: 6
05-04-2012 дата публикации

Composition Comprising a Monomer with a Polyalicyclic Structure Element for Filling and/or Sealing a Root Canal

Номер: US20120082954A1
Автор: Manfred Stepputtis, Manfred Thomas Plaumann, Nils Fontein, Reinhard Maletz, Tobias Blömker
Принадлежит: VOCO GmbH

A curable dental composition comprising a monomer with a polyalicyclic structure element that can be used for filling and/or sealing of a root canal is described. Also described is a composition useful as a dental material and a method for preparing such a composition. New polymerizable monomers comprising at least one polyalicyclic structure element and certain ethylenic structure elements, which are particularly suitable for use in a dental composition, and the use of the new monomers in a dental composition are also described.

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Номер записи: 7
19-04-2012 дата публикации

Oral care compositions comprising a polymeric dye

Номер: US20120093905A1
Автор: Andrew Joiner, Carole Jane Philpotts, Jinfang Wang, Qingsheng Tao, Sheng Meng, Stephen Norman Batchelor
Принадлежит: Conopco Inc

An oral care composition comprising a dye polymer, for modifying the colour of teeth.

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Номер записи: 8
28-06-2012 дата публикации

Method of using apparatus for preventing plaque, preventing cativies and keeping teeth clean

Номер: US20120164082A1
Автор: Grace Yum Zimmermann, Kent Zimmermann
Принадлежит: Individual

A method for using an apparatus to gently clean an adult's or a child's teeth, gums, mouth, cheek surfaces and tongue with a liquid-filled cotton swab containing a proprietary solution that uses a natural sugar, in this case xylitol, that may prevent plaque from sticking to the user's teeth. Application of the xylitol solution may also kill bacteria and help prevent cavities from forming. The swab may be particularly useful for people that may have difficulty in brushing or flossing, such as victims of stroke or paralysis, people who cannot fully open their mouths, wearers of orthodontia, children, and babies.

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Номер записи: 9
16-08-2012 дата публикации

Low water stannous fluoride plus zinc citrate dentifrice with improved stability, rheology, and efficacy

Номер: US20120207686A1
Автор: Linh Fruge, Michael Prencipe, Steven Wade Fisher
Принадлежит: Colgate Palmolive Co

A dentifrice composition having a low water phase comprising effective amounts of polyphosphate and ionic active ingredients.

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Номер записи: 10
06-09-2012 дата публикации

System And Method For Packet Profiling

Номер: US20120227109A1
Автор: Jeffrey D. DIMURO
Принадлежит: JPMorgan Chase Bank NA

Systems and methods for packet profiling are disclosed. According to one embodiment, a method for profiling incoming data packets for an organization includes the steps of (1) receiving, at an interface for a transport provider, a data packet; (2) using a computer processor, analyzing the data packet; (3) using the computer processor, based on the analysis, marking the data packet; and (4) transmitting the data packet to the organization.

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Номер записи: 11
20-09-2012 дата публикации

Dental composition

Номер: US20120238662A1
Автор: Helmut Ritter, Joachim E. Klee, Mareike Bardts, Oliver Elsner, Sven Pohle
Принадлежит: DENTSPLY DETREY GMBH

Dental cement composition comprising a polymerizable polyacidic polymer having repeating units in the polymer backbone, which are represented by the following formula (I)1 (II), and/or (III): wherein X represents O, S, or NR′, whereby R′ represents a hydrogen atom or a straight or branched C 1 -C 6 alkyl group, C 3 -C 6 cycloalkyl group, or C 4 -C 8 cycloalkylalkyl group, Y a group of the following formula (IV), wherein each of L 1 , L 2 , L 3 and L 4 , which are independent from each other represents a single bond, a straight or branched C 1 -C 6 alkylene group, a straight or branched C 1 -C 6 alkenylene, or a straight or branched C 1 -C 20 alkylene group which includes 1 to 8 atoms selected from oxygen and sulfur atoms, X′ represents O, S, or NR″, whereby R″ represents a hydrogen atom or a straight or branched C 1 -C 6 alkyl group, C 3 -C 6 cycloalkyl group, or C 4 -C 8 cycloalkylalkyl group, m is 0 to 3, and n is 1 to 3.

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Номер записи: 12
27-09-2012 дата публикации

Process for the preparation of aromatized chewing foams for cosmetic products

Номер: US20120244201A1
Автор: Claudia Letmathe, Dirk Schwannecke, Gabriele Rohé, Hartwig Kempkes, Jens Hepperle, Meike Niesten, Sebastian Dörr, Steffen Hofacker, Thorsten KRÄMER, Thorsten Rische
Принадлежит: BAYER MATERIALSCIENCE AG

The invention relates to a process for the preparation of novel aromatized chewing foams for the oral care sector based on polyurethane-polyureas and aromatizing compositions.

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Номер записи: 13
06-12-2012 дата публикации

Composition for cleaning teeth comprising natural glass and related methods

Номер: US20120308626A1
Автор: BO Wang
Принадлежит: Imerys Filtration Minerals Inc

A composition for cleaning teeth may include natural glass, wherein the natural glass has a top particle size (d 90 ) less than 50 μm and a median particle size (d 50 ) less than 30 μm, and wherein the natural glass ranges from 0.1 percent to 20 percent by weight of the composition. A natural glass composition may have a top particle size (d 90 ) less than 50 μm, a median particle size (d 50 ) less than 30 μm, and exhibit an RDA value less than 220. The composition for cleaning teeth may include a toothpaste base.

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Номер записи: 14
27-12-2012 дата публикации

Cell construct comprising polymer blocks having biocompatibility and cells

Номер: US20120329157A1
Автор: Kentaro Nakamura
Принадлежит: Fujifilm Corp

It is an object of the present invention to provide a cell three-dimensional construct that has a thickness sufficient for tissue regeneration and comprises cells uniformly distributed therein. The present invention provides a cell construct comprising polymer blocks having biocompatibility and cells, wherein the plural polymer blocks are arranged in spaces between the plural cells.

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Номер записи: 15
21-03-2013 дата публикации

HIGH-PURITY STEVIOL GLYCOSIDES

Номер: US20130071339A1
Автор: MARKOSYAN Avetik
Принадлежит:

Methods of preparing highly purified steviol glycosides, particularly Rebaudioside D, are described. The methods include purification from the extraction stage of the Bertoni plant, purification of steviol glycoside mixtures, Rebaudioside D and Rebaudioside A from a commercial Stevia extract, and purification of Rebaudioside D from remaining solutions obtained after isolation and purification of Rebaudioside A and a high purity mixture of steviol glycosides. The methods are useful for producing high purity Rebaudioside D, Rebaudioside A, and steviol glycoside mixtures. The high purity steviol glycosides are useful as non-caloric sweeteners in edible and chewable compositions such as any beverages, confectioneries, bakery products, cookies, and chewing gums. 1. A method for purifying steviol glycosides , comprising the steps of:a. providing a solution of steviol glycosides;b. passing the solution of steviol glycosides through a multi-column system including a plurality of columns packed with an adsorbent resin, to obtain at least one column having adsorbed steviol glycosides;c. removing impurities from the multi-column system; andd. eluting the adsorbed steviol glycosides from the at least one column, to obtain an eluted solution comprising steviol glycosides.2. The method of claim 1 , wherein impurities are removed by eluting the multi-column system with a washing solution.3. The method of claim 2 , wherein the washing solution comprises an aqueous alcohol solution having a water to alcohol ratio ranging from about 99.9:0.1 to about 60:40.4. The method of claim 1 , wherein the adsorbed steviol glycosides are eluted with an aqueous alcohol solution having a water to alcohol ratio ranging from about 60:40 to about 0.1:99.9.5. The method of claim 1 , wherein at least two columns of the plurality of columns are connected in series.6. The method of claim 1 , wherein at least two columns of the plurality of columns are connected in parallel.7. The method of claim 1 , ...

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Номер записи: 16
21-03-2013 дата публикации

ENCAPSULATION OF INGREDIENTS IN LACTOSE MATRIX TO FORM ACTIVE ENCAPSULATES

Номер: US20130071456A1
Автор: Boyd Thomas, Collins Michael, Fruge Linh, Hepler Barbara
Принадлежит: Colgate-Palmolive Company

An oral care composition and method are described in which the composition includes lactose matrix encapsulates entrained in a carrier. The encapsulates may further comprise oral care and/or personal care ingredients. 1. An encapsulate composition comprising:at least one oral care and/or personal care ingredient encapsulated in a matrix comprising:a lactose monohydrate; anda microcrystalline cellulose, wherein the lactose monohydrate is present in an amount of 50% to 75% by weight.2. The encapsulate of claim 1 , wherein the encapsulate further comprises a coloring agent.3. The encapsulate of claim 2 , wherein the coloring agent comprises at least one coloring agent chosen from titanium dioxide claim 2 , a dye claim 2 , a pigment claim 2 , a colorant claim 2 , or an opacifying agent.4. The encapsulate of claim 1 , wherein the at least one oral care and/or personal care ingredient comprises at least one ingredient chosen from of zinc citrate claim 1 , stannous fluoride claim 1 , cetylpyridinium chloride claim 1 , and L-arginine.5. (canceled)6. The encapsulate of claim 1 , wherein the microcrystalline cellulose is present in an amount of 25% to 40% by weight.7. The encapsulate of claim 3 , wherein the titanium dioxide is present in an amount of 0.1% to 2% by weight.8. The encapsulate of claim 1 , wherein the at least one oral care and/or personal care ingredient is present in an amount of 0.1% to 50% by weight.9. The encapsulate of claim 1 , wherein the encapsulate has a size of 0.5 mm to 5 mm in diameter.10. The encapsulate of claim 1 , wherein the encapsulate contains a combination of lactose monohydrate and microcrystalline cellulose such that when used in an oral care composition claim 1 , the encapsulate is capable of dissolving in the oral cavity during the use of the oral care composition to release an ingredient to the oral cavity.11. A composition comprising the encapsulate composition of and a carrier.12. The composition of claim 10 , wherein the carrier is ...

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Номер записи: 17
28-03-2013 дата публикации

ADHESIVE DENTAL BLEACHING COMPOSITIONS CONTAINING POLYVINYLPYRROLIDONE

Номер: US20130078195A1
Автор: Chen Tianming
Принадлежит: ULTRADENT PRODUCTS, INC.

A dental bleaching composition comprises a dental bleaching agent and a polyvinylpyrrolidone thickening agent. The bleaching composition may include water, flavoring agents, a basic substance and desensitizing agents, as desired. Polyvinylpyrrolidone avoids acid etching and chelation of teeth that were problematic in bleaches using carbomer as a thickener. A delivery system for delivering the bleaching composition comprises the aforementioned dental bleaching composition in combination with a moisture-resistant barrier layer such as a dental tray or a flexible strip of material. 1. An adhesive one-part dental bleaching composition for bleaching a person's teeth , comprising:a dental bleaching agent selected from the group consisting of hydrogen peroxide, carbamide peroxide, sodium perborate, sodium percarbonate, and combinations thereof;water in an amount of at least 0.1% by weight of said dental bleaching composition; andpolyvinylpyrrolidone included in an amount of at least about 10% by weight so that said dental bleaching composition is highly viscous and adhesive when applied to a person's teeth.2. An adhesive one-part dental bleaching composition as in claim 1 , said polyvinylpyrrolidone comprising at least about 25% by weight of the dental bleaching composition.3. An adhesive one-part dental bleaching composition as in claim 1 , said polyvinylpyrrolidone having a molecular weight in a range of about 90 claim 1 ,000 to about 1 claim 1 ,500 claim 1 ,000.4. An adhesive one-part dental bleaching composition as in claim 1 , said polyvinylpyrrolidone having a molecular weight in a range of about 1 claim 1 ,000 claim 1 ,000 to about 1 claim 1 ,500 claim 1 ,000.5. An adhesive one-part dental bleaching composition as in claim 1 , wherein said tooth adhesion agent is included in an amount that exceeds an amount of said dental bleaching agent in the dental bleaching composition.6. An adhesive one-part dental bleaching composition as in claim 1 , said water having a ...

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Номер записи: 18
28-03-2013 дата публикации

DENTAL STERILIZING WATER, METHOD FOR PRODUCING THE WATER, AND DEVICE FOR PRODUCING THE WATER

Номер: US20130078196A1
Автор: NOGUCHI Munenori
Принадлежит: PERFECT PERIO CO., LTD.

This aims to produce dental sterilizing water having not only a sterilizing action but also an action to break a bio-film. Provided is a sterilizing water producing device () comprising a stock solution tank () for storing a stock solution (), a stroke pump () connected in communication to the stock solution tank, an electrolytic bath () connected in communication to the stroke pump, a discharge pipe () connected in communication to the electrolytic bath, and a dilution water tank () reserving dilution water (). The dilution water tank () is so positioned relative to the tip position of the discharge pipe () that the tip of the discharge pipe () may be lower than the water level of the dilution water () reserved in the dilution water tank (). The stock solution () is prepared by selecting any of the methods shown at (a-1) to (d). 131-. (canceled)32. A method for producing dental sterilizing water comprising preparing an aqueous stock solution containing sodium chloride and carbon dioxide; and electrolyzing the aqueous stock solution so that the effective chlorine concentration is from 50 to 700 ppm , the pH is from 6.3 to 8 , and hypochlorous acid and sodium hydrogen carbonate are produced.33. The method for producing dental sterilizing water according to claim 32 , wherein the aqueous stock solution is prepared by forcing water to pass through a reverse osmosis membrane; adding sodium chloride to the passed water; and either blowing carbon dioxide gas into the water or adding dry ice to the water before claim 32 , after claim 32 , or simultaneously with claim 32 , the step of adding sodium chloride to the water.34. The method for producing dental sterilizing water according to claim 32 , wherein the aqueous stock solution is prepared by adding sodium chloride to purified or distilled water; and either blowing carbon dioxide gas into the water or adding dry ice to the water before claim 32 , after claim 32 , or simultaneously with claim 32 , the step of adding ...

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Номер записи: 19
28-03-2013 дата публикации

NOVEL USE

Номер: US20130078198A1
Автор: Aitken Gail Cameron, Churchley David Raymond
Принадлежит: Glaxo Group Limited

This invention relates to the use of sodium dodecylbenzene sulphonate (SDDBS) for helping to prevent or remove surface deposited stains from natural teeth and dental prostheses and oral care compositions comprising SDDBS for such use. 1. An oral care composition comprising sodium dodecylbenzene sulphonate (SDDBS) for use in combating stain from a dental surface.2. A composition according to further comprising a source of zinc ions.3. A composition according to wherein the source of zinc ions is selected from zinc chloride claim 2 , zinc citrate claim 2 , zinc acetate claim 2 , zinc sulphate claim 2 , zinc gluconate claim 2 , zinc salicylate claim 2 , zinc lactate claim 2 , zinc malate claim 2 , zinc maleate claim 2 , zinc tartrate claim 2 , zinc carbonate claim 2 , zinc zinc phosphate claim 2 , zinc oxide or zinc sulphate.4. A composition according to wherein the source of zinc ions is zinc chloride.5. A composition according to further comprising 4-isopropyl-3-methylphenol (IPMP).6. A composition according to which is a mouthwash or a toothpaste.7. A composition according to which is a mouthwash.8. (canceled)9. A method for combating stain from a dental surface claim 1 , said method comprising applying an oral care composition comprising an effective amount of SDDBS to the dental surface. This invention relates to the use of sodium dodecylbenzene sulphonate (SDDBS) for combating (ie helping to prevent or remove) surface deposited stains from natural teeth and dental prostheses and oral care compositions comprising SDDBS for such use. Suitable compositions include mouthwash and dentifrice compositions.Several factors contribute to tooth discoloration but the three main factors are believed to be: i) formation of plaque and tartar matrices on the tooth surface which then entraps stains, ii) ingestion of certain drugs during tooth formation, and iii) discoloration due to oral cavity traumatization following which blood break-down products seep into the mineralized ...

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Номер записи: 20
04-04-2013 дата публикации

ORAL CARE COMPOSITIONS

Номер: US20130084253A1
Автор: Brading Melanie Gayle, Golding Stephen, Green Alison Katharine, Littlewood David Thomas, Scott Ann Elizabeth
Принадлежит:

The invention provides an oral care composition (preferably a dentifrice) comprising one or more curcumin compounds and a source of zinc ions. The incorporation of a source of zinc ions into the composition suppresses the degradation and/or discoloration of the curcumin compound(s) in the composition. 1. An oral care composition comprising one or more curcumin compounds and a source of zinc ions.2. An oral care composition according to claim 1 , in which the curcumin compound is a mixture of tetrahydrocurcumin claim 1 , tetrahydrodemethoxycurcumin and tetrahydrobis-demethoxycurcumin.3. An oral care composition according to claim 1 , in which the source of zinc ions is zinc citrate.4. An oral care composition according to claim 1 , which is in the form of a dentifrice and which comprises abrasive cleaning agent claim 1 , water claim 1 , humectant claim 1 , binder or thickening agent claim 1 , and surfactant.5. The use of a source of zinc ions for suppressing the degradation and/or discoloration of curcumin compound(s) in an oral care composition. The present invention is concerned with oral care compositions. More particularly, the present invention is concerned with oral care compositions containing curcumin compounds.Curcumin compounds have antioxidant properties and may be used in oral care compositions to exert beneficial physiological effects, such as prevention or amelioration of gingivitis or periodontitis. GB 2317339 discloses oral compositions for prevention and treatment of dental caries, periodontal diseases and other diseases of the oral cavity. The compositions include a curcuminoid and a fluoride ion source, in combination with oral care actives and carrier materials. SU 1,132,945 discloses incorporating extracts of turmeric or ginger into toothpaste compositions for improved anti-inflammatory effect on tissues of the oral cavity and treatment of certain diseases of the mucous membranes of the oral cavity and marginal periodontitis.However, the ...

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Номер записи: 21
11-04-2013 дата публикации

ORAL CARE COMPOSITIONS AND METHODS

Номер: US20130089506A1
Автор: Brown James R., Trivedi Harsh M., Vazquez Joe, Wang Wei
Принадлежит: Colgate-Palmolive Company

Disclosed are oral care compositions and the use of such oral care compositions for inhibiting co-aggregation of oral bacteria and inhibiting bacterial growth. Also disclosed are methods for inhibiting co-aggregation of oral bacteria and inhibiting bacterial growth. The oral care composition includes cranberry extract non-dialyzable material, in which the cranberry extract non-dialyzable material is present in an amount effective to inhibit co-aggregation of oral bacteria and/or inhibit bacterial growth. 1) An oral care composition comprising cranberry extract non-dialyzable material and an orally acceptable vehicle , wherein the cranberry extract non-dialyzable material is present in a concentration of 0.08-1.33 mg/ml , and wherein the composition does not contain a component that deactivates the cranberry extract non-dialyzable material.2) An oral care according to claim 1 , wherein the cranberry extract non-dialyzable material is present in the composition in a concentration of about 0.3% w/w.3) An oral care composition according to claim 1 , wherein the orally acceptable vehicle is selected from one or more of the group consisting of water claim 1 , alcohol claim 1 , a humectant claim 1 , and combinations thereof.4) An oral care composition according to claim 3 , wherein the alcohol is ethanol.5) An oral care composition according to claim 4 , wherein the alcohol is present in a concentration of about 6% w/w.6) An oral care composition according to claim 3 , wherein the humectant is selected from the group consisting of one or more of sorbitol claim 3 , glycerine claim 3 , and mixtures thereof.7) An oral care composition according to claim 6 , wherein the humectant is present in a concentration of about 10% w/w.8) An oral care composition according to claim 1 , wherein the composition is a mouthrinse.9) An oral care composition according to claim 1 , wherein the composition further comprises one or more agents selected from the group consisting of an anti-plaque ...

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Номер записи: 22
11-04-2013 дата публикации

SODIUM-HYPOCHLORITE-BASED BODY WASH COMPOSITIONS

Номер: US20130089628A1
Автор: Anwar Azam, Cockerell Clay J., Sitbon Catherine
Принадлежит: TOPMD, INC.

Sodium hypochlorite-based compositions that are non-toxic and have antimicrobial and cleansing properties may include from about 0.025% to about 10% by weight of sodium hypochlorite. For example, the compositions may include less than 1% by weight of sodium hypochlorite (e.g., less than 0.5% by weight of sodium hypochlorite). The compositions may further include sodium laureth sulfate, cocamidopropyl betaine, cocamide MEA, disodium EDTA, and deionized water. Such compositions may be applied externally to a mammalian body through rinse-off or leave-on applications. Compositions also may be incorporated as a component of other products, such as deodorants, towelettes, or powders. 1. A body wash composition comprising:from 0.1 wt % to 10 wt % of an alkali metal or alkaline earth metal hypochlorite;an anionic surfactant that includes an alkyl sulfate;a nonionic surfactant that includes an alkonolamide;an amphoteric surfactant; anda chelating agent.2. The body wash composition of claim 1 , wherein the anionic surfactant ranges from 3 wt % to 40 wt % of the body wash composition claim 1 , the nonionic surfactant ranges from 1 wt % to 7 wt % of the body wash composition claim 1 , the amphoteric surfactant ranges from 0.5 wt % to 7 wt % of the body wash composition claim 1 , and the chelating agent ranges from approximately 0.1 wt % to 3 wt % of the body wash composition.3. The body wash composition of claim 2 , further comprising water.4. The body wash composition of claim 1 , wherein the alkyl sulfate includes at least one of sodium lauryl sulfate claim 1 , triethanol amine lauryl sulfate claim 1 , ammonium lauryl sulfate claim 1 , and sodium laureth sulfate.5. The body wash composition of claim 4 , wherein the alkyl sulfate includes sodium laureth sulfate.6. The body wash composition of claim 1 , wherein the alkonolamide includes at least one of cocamide monoethanolamide claim 1 , cocamide diethanolamide claim 1 , lauramide monoethanolamide claim 1 , and lauramide ...

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Номер записи: 23
18-04-2013 дата публикации

NON-AQUEOUS ORAL CARE COMPOSITIONS

Номер: US20130095045A1
Автор: GROVES Brian Joseph, WATERFIELD Philip Christopher
Принадлежит:

The invention provides a non-aqueous oral care composition with a liquid continuous phase comprising a thickening agent, a humectant, and one or more liquid polyethylene glycols having a melting point below 25° C., in which the liquid continuous phase is structured with crystals of one or more solid polyethylene glycols having a melting point of 25° C. or above. The rheological behaviour of the composition of the invention corresponds well with the characteristic rheological behaviour of typical aqueous dentifrice formulations. 1. A non-aqueous oral care composition with a liquid continuous phase comprising a thickening agent , a humectant , and one or more liquid polyethylene glycols having a melting point below 25° C. , in which the liquid continuous phase is structured with crystals of one or more solid polyethylene glycols having a melting point of 25° C. or above.2. A composition according to claim 1 , in which the carboxyvinyl polymer has a molecular weight of at least 750 claim 1 ,000 g/mol.3. A composition according to claim 1 , in which the carboxyvinyl polymer is selected from homopolymers of acrylic acid cross-linked with allyl ethers of sucrose or pentaerythritol; and homopolymers of acrylic acid cross-linked with divinyl glycol.4. A composition according to claim 1 , in which the humectant is one or more organic polyols having 3 or more hydroxyl groups in the molecule.5. A composition according to claim 1 , in which the solid polyethylene glycol has a melting point ranging from 35 to 65° C.6. A composition according to claim 1 , in which the solid polyethylene glycol has the general formula H(OCHCH)OH claim 1 , where n is the number of repeating oxyethylene units claim 1 , and the average value of n ranges from 60 to 75.7. A composition according to claim 1 , in which the liquid polyethylene glycol has a melting point ranging from −15 to 8° C.8. A composition according to claim 1 , in which the liquid polyethylene glycol has the general formula H(OCHCH) ...

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Номер записи: 24
18-04-2013 дата публикации

FLAVOR RELEASE FROM MULTILAYER FILM DURING BRUSHING

Номер: US20130095159A1
Автор: Boyd Thomas, Gu Ben, Lin Nora, Wang Wei
Принадлежит: Colgate-Palmolive Company

Oral care compositions which provide enhanced flavour release, and which comprise a multilayer film and an orally acceptable carrier. The carrier contains a first flavour and the film has a centre layer containing a second flavour disposed between two outer surface layers. The first and second flavours may be identical or different. Each layer for the film may comprise a film forming polymer, e.g. hydroxypropylmethyl cellulose. The outer layers may comprise a release modulating agent, e.g. polyvinyl acetate or hydroxyethyl cellulose. The carrier may be a dentifrice or mouthwash. 1. An oral care composition having enhanced flavor release comprisingan orally acceptable carrier containing a first flavor; anda multilayer film, the multilayer film including a center layer disposed between two outer surface layers;wherein said center layer contains a second flavor.2. The composition of claim 1 , wherein each layer comprises a film forming polymer.3. The composition of claim 2 , wherein the film forming polymer is selected from hydroxypropylmethyl cellulose claim 2 , methyl cellulose claim 2 , hydroxypropyl cellulose and mixtures of copolymers thereof.4. The composition of claim 2 , wherein the film forming polymer comprises from about 25% to about 75% by weight of the multilayer film.5. The composition of claim 1 , wherein at least one of said outer surface layers further comprise a release modulating agent.6. The composition of claim 5 , wherein the release modulating agent is polyvinyl acetate or hydroxyethyl cellulose.7. The composition of claim 5 , wherein the release modulating agent comprises from about 5% to about 30% by weight of the multilayer film.8. The composition of claim 1 , wherein the orally acceptable carrier is a dentifrice or a mouthwash.9. The composition of claim 1 , wherein the thickness of each outer surface layer is from about 0.1 mils to about 4 mils.10. The composition of claim 9 , wherein the thickness of each outer surface layer is from about 0 ...

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Номер записи: 25
25-04-2013 дата публикации

Composition for treating and/or preventing periodontal disease

Номер: US20130101529A1
Автор: KAWABE Mitsuo, Tsuchida Kotarou, TSUCHIDA Yuuzou, Watanabe Kunitomo
Принадлежит:

A method for preventing periodontal disease, which comprises administering an effective amount of a composition to a method for preventing periodontal disease comprising administering an effective amount of a composition to a part in an oral cavity before a periodontal disease-related bacteria, a decayed teeth-related bacteria, and/or spp. is/are abnormally proliferated in the oral cavity, wherein said composition comprises a extract and malic acid. 1. A method for preventing periodontal disease comprising:{'i': 'Candida', 'administering an effective amount of a composition to a part in an oral cavity before a periodontal disease-related bacteria, a decayed teeth-related bacteria, and/or spp. is/are abnormally proliferated in the oral cavity,'}{'i': 'Sasa', '(a) wherein said composition comprises a extract and malic acid,'}{'i': 'Sasa', '(b) wherein said extract is prepared by extracting raw leaves or dried leaves with water,'}{'i': 'Sasa', '(c) wherein said extract is contained in a concentration as expressed in terms of the solid content ranging from 2 to 25% by mass, and'}(d) wherein said malic acid is contained in a concentration of from 0.01 to 5% by mass.2. The method according to claim 1 , wherein the composition is administered in an amount of 0.01 to 0.1 g/1 kg of body weight claim 1 , at a frequency of 1 to 5 times a day.3. The method according to claim 1 , wherein the composition is administered in an amount of 0.1 to 1 g claim 1 , at a frequency of 1 to 5 times a day.4. The method according to claim 1 , wherein said malic acid is contained in a concentration of from 0.02 to 3% by mass.5. The method according to claim 2 , wherein said malic acid is contained in a concentration of from 0.02 to 3% by mass.6. The method according to claim 1 , wherein said composition further comprises an oily component and a creaming agent claim 1 ,said oily component is at least one member selected from the group consisting of squalane, tallow, lard, horse fat, lanolin, ...

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Номер записи: 26
25-04-2013 дата публикации

MULTILAYER FILMS FOR DELIVERY OF FLAVOR

Номер: US20130101652A1
Автор: Boyd Thomas, Gu Ben, Leigh Leonora
Принадлежит:

An oral care composition having enhanced flavor release comprising an orally acceptable carrier containing a first flavor and a multilayer film for extended or delayed flavor release, the multilayer film including at least a center layer containing a second flavor, the center layer positioned between two outer surface layers, each surface layer including a release modulating agent, the first and second flavor being the same or different. The film is adapted to adhere to an oral cavity surface and the outer surface layers may comprise a mucoadhesive polymer, e.g. carboxy polymethylene, polycarbophil or polyvinyl pyrrolidone, and a film forming polymer, eg. hydroxypropylmethyl cellulose (HPMC). Suitable release modulating agents include HPMC and polyvinyl acetate. The carrier may be a toothpaste or mouthwash. 2. The composition of claim 1 , wherein said second flavor is released from said multilayer film at a rate effective to deliver said second flavor to the oral cavity after said multilayer film adheres to an oral cavity surface.3. The composition of claim 2 , wherein said multilayer film further comprises an active material.4. The composition of claim 2 , wherein the outer surface layers comprise the same materials.5. The composition of claim 2 , wherein the release modulating agent is selected from polyvinyl acetate; hydroxypropylmethyl cellulose; and hydroxyethyl cellulose and the release modulating agent is present in an amount from about 5% to about 30% by weight of the multilayer film.6. (canceled)7. The composition of claim 4 , wherein said outer surface layers and said center layer comprise a film forming polymer.8. The composition of claim 7 , wherein the film forming polymer is selected from hydroxypropylmethyl cellulose claim 7 , methyl cellulose claim 7 , hydroxypropyl cellulose and a combination of two or more thereof.9. The composition of claim 8 , wherein the release modulating agent is selected from polyvinyl acetate; hydroxypropylmethyl cellulose; ...

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Номер записи: 27
02-05-2013 дата публикации

Chemical Treatments for the Disruption of Dental Plaque Biofilms and Related Methods

Номер: US20130108560A1
Автор: Ed Maliski, Eric Allen, Robert Davidson
Принадлежит: Ed Maliski, Eric Allen, Robert Davidson

A thin film composition for oral administration that adheres to and dissolves in a mouth of a user, wherein the thin film is a single layered water-soluble solid comprising at least one D-amino acid contained in a plurality of hydrophobic carriers dispersed throughout the thin film. The hydrophobic carriers comprise oil and the composition further comprises a phospholipid, an emulsifier, and a water soluble polymer. The preferred D-amino acids are D-leucine, D-tryptophan, D-methionine, and D-tyrosine. A method of reducing dental plaque in a subject entails placing the thin film composition contemplated herein into a mouth of the subject.

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Номер записи: 28
02-05-2013 дата публикации

ABRASIVE CONFECTIONARY PRODUCTS

Номер: US20130108677A1
Автор: Harpaz Shimon
Принадлежит: BREEZY INDUSTRIES LTD.

There is provided a consumable abrasive confectionery product for the reduction of oral malodor and for treatment of other oral cavity conditions, comprising substantially uniformly dispersed abrasive particles configured to at least partially erode deposits in the oral cavity, wherein the abrasive quality of the confectionery product is substantially constant as the confectionery product is consumed and wherein the use of the product does not induce a gag reflex. 1. A consumable abrasive confectionery product adapted to reduce oral malodor comprising substantially uniformly dispersed abrasive particles configured to at least partially erode , scrub , loosen and/or abrade deposits in the oral cavity , wherein the abrasive quality of the confectionery product is substantially constant as the confectionery product is consumed.2. The confectionery product according to claim 1 , wherein the abrasive quality is in the range of about 10-20 gr/cm.3. The confectionery product according to claim 1 , wherein the abrasive quality is in the range of about 13-18 gr/cm.4. The confectionery product according to claim 1 , wherein the density of the particles is in the range of about 0.1-2 gr/ml.5. The confectionery product according to claim 1 , wherein the confectionery product further comprises a stick partially disposed in the confectionery product claim 1 , wherein the stick is a safety stick claim 1 , a tooth pick claim 1 , or both.6. The confectionery product according to claim 1 , wherein the oral cavity comprises tongue claim 1 , cheek claim 1 , palate claim 1 , teeth claim 1 , gum claim 1 , and combinations thereof.7. The confectionery product according to wherein the particles are structured to at least partially erode claim 6 , scrub claim 6 , loosen and/or abrade deposits on the inner grooves and/or on dorsal region of the tongue.8. The confectionery product according to claim 1 , wherein the particles are selected from granules claim 1 , capsules claim 1 , or both.9. ...

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Номер записи: 29
02-05-2013 дата публикации

HYPOCHLORITE DENTURE COMPOSITIONS AND METHODS OF USE

Номер: US20130109608A1
Автор: Rumberger Evan, Smith William L.
Принадлежит: The Clorox Company

A solid composition including calcium and/or magnesium hypochlorite, a builder (e.g., one or more of carbonate, bicarbonate, sesquicarbonate), an acid, a water-soluble polymer, at least one anionic surfactant, and optionally, a hydrotrope. The composition does not include any potassium hypochlorite, sodium hypochlorite, lithium hypochlorite, N-halogenated compounds, peroxides, persulfates, hydantoins, isocyanurates, or carboxylic acids that also have hydroxyl, amino, amido, imino, or imido groups. Upon dissolution of the composition in water, the calcium and/or magnesium hypochlorite and acid react to form hypochlorous acid. The use of hypochlorous acid, rather than direct use of an alkaline or alkaline earth hypochlorite results in a composition that is typically acidic rather than basic, and that results in improved cleaning. The composition is particularly suited tor cleaning and disinfecting dentures. 1. A solid , one-layered composition comprising:i. a hypochlorite selected from the group consisting of calcium hypochlorite, magnesium, hypochlorite and mixtures thereof;ii. a builder selected from the group consisting of carbonate, bicarbonate, sesquicarbonate and mixtures thereof;iii. at least 30% by weight of an acid selected from the group consisting of a carboxylic acid, a dicarboxylic acid, a sulfonic acid, an acid sulfate, an acid phosphate, and mixtures thereof;iv. a water-soluble polymer selected from the group consisting of a polycarboxylate, a sulfonated caxboxylate, a polysulfonate, a polyvinylpyrrolidone, a polypyridinium salt, a polyquaternary ammonium salt, and mixtures thereof; andwherein the composition does not contain potassium hypochlorite, sodium hypochlorite, lithium, hypochlorite, N-halogenated compounds, peroxides, persulfates, hydantoins, isocyanurates, carboxylic acids that also have hydroxyl, amino, amido, imino, or imido groups;wherein the composition contains only one layer.2. The composition of claim 1 , wherein the hypochlorite is ...

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Номер записи: 30
16-05-2013 дата публикации

Selection and Use of Lactic Acid Bacteria for Reducing Dental Caries and Bacteria Causing Dental Caries

Номер: US20130121932A1
Автор: Connolly Eamonn, Mollstam Bo
Принадлежит:

New strains of that have been selected for their capability of improved reduction the number of in the mouth of mammals through inhibiting activity in combination with better binding to the oral mucins and dental plaque, thereby preventing, reducing or treating dental caries, and products derived from said strains, including agents for treatment or prophylaxis of caries for administration to humans. 1Lactobacillus reuteri. A biologically pure culture of strain FJ1 “Prodentis” (ATCC PTA-5289).2Lactobacillus reuteri. A biologically pure culture of strain FJ3 (ATCC PTA-5290).3LactobacillusStreptococcus mutans. A biologically pure culture of selected for its ability of reducing the number of in the mouth for prophylaxis or treatment of dental caries in mammals using a selection assay of inhibiting activity in combination with good binding to oral mucins.4Lactobacillus reuteri. A product for inhibiting the growth of dental caries bacteria , comprising cells of at least one strain of selected have inhibitory activity against cariogenic bacteria in combination with good binding to oral mucins.5Lactobacillus reuteriLactobacillus reuteri. The product according to claim 4 , wherein the at least one strain is selected from the group consisting of: strain FJ1 “Prodentis” (ATCC PTA-5289) claim 4 , and strain FJ3 (ATCC PTA-5290).6. The product according to claim 4 , wherein the product is a food product.7. The product according to claim 6 , wherein the food product is selected from the group consisting of yogurt claim 6 , jelly claim 6 , pudding claim 6 , chewing gum claim 6 , lozenge claim 6 , candy claim 6 , chocolate claim 6 , biscuit claim 6 , cookie claim 6 , cheese claim 6 , juice and tea8. The product according to claim 6 , wherein the food product is a milk-containing product.9. The product according to claim 8 , wherein the food product is yogurt.10. The product according to claim 4 , wherein the product is a dental treatment product.11. The product according to claim 10 ...

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Номер записи: 31
23-05-2013 дата публикации

ORAL CARE COMPOSITIONS

Номер: US20130129642A1
Автор: Joiner Andrew, Philpotts Carole Jane
Принадлежит:

The invention provides an oral care composition suitable for delivering a temporary whitening effect to the surface of teeth, the composition comprising: a continuous phase comprising water or polyhydric alcohol or a mixture thereof; a tooth surface whitening agent which is dispersed in the continuous phase, and a deposition aid for the tooth surface whitening agent; characterised in that the tooth surface whitening agent is a lake dye formed by fixing a dye onto a particulate inorganic substrate, in which the dye used to form the lake dye is a triarylmethane dye having a blue to green-blue colour with a hue angle in the CIELAB system ranging from 180 to 270 degrees, and in which the amount of lake dye is at least 0.015% by total weight lake dye based on the total weight of the composition. 1. An oral care composition suitable for delivering a temporary whitening effect to the surface of teeth , the composition comprising:a continuous phase comprising water or polyhydric alcohol or a mixture thereof;a tooth surface whitening agent which is dispersed in the continuous phase, anda deposition aid for the tooth surface whitening agent;characterised in that the tooth surface whitening agent is a lake dye formed by fixing a dye onto a particulate inorganic substrate, in which the dye used to form the lake dye is a triarylmethane dye having a blue to green-blue colour with a hue angle in the CIELAB system ranging from 180 to 270 degrees, and in which the amount of lake dye is at least 0.015% by total weight lake dye based on the total weight of the composition.2. An oral care composition according to claim 1 , in which the dye used to form the lake dye has a hue angle in the CIELAB system ranging from 180 to 200 degrees.3. An oral care composition according to claim 1 , in which the particulate inorganic substrate onto which the dye is fixed is hydrated alumina.4. An oral care composition according to claim 1 , in which the deposition aid is a poly(carboxylic acid) polymer ...

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Номер записи: 32
23-05-2013 дата публикации

ORAL CARE COMPOSITIONS

Номер: US20130129643A1
Автор: Boyd Thomas, Mirajkar Yelloji-Rao K., Prencipe Michael, Xu Guofeng, Yang Ying
Принадлежит: Colgate-Palmolive Company

An oral care composition for treating or preventing calculus comprising an anticalculus agent and an antibacterial agent comprising a biphenol compound obtainable from wherein the composition is free of phosphate-containing anticalculus agents. 2. The oral care composition of claim 1 , wherein the anticalculus agent consists essentially of a zinc ion source.3. The oral care composition of claim 1 , wherein the zinc ion source comprises zinc oxide.4Magnolia. The oral care composition of claim 1 , wherein the antibacterial agent is selected from magnolol claim 1 , honokiol claim 1 , tetrahydromagnolol claim 1 , tetrahydrohonokiol claim 1 , propylmagnolol claim 1 , propylhonokiol claim 1 , isopropylmagnolol claim 1 , isopropylhonokiol claim 1 , butylmagnolol claim 1 , and butylhonokiol.5Magnolia. The oral care composition of claim 1 , wherein the antibacterial agent comprises magnolol.6. The oral care composition according to claim 1 , wherein the composition further comprises sodium sulphate and sodium lauryl sulphate.7. The oral care composition according to claim 1 , wherein the composition comprises at least 1.6% by weight of sodium lauryl sulphate.8. The oral care composition according to claim 1 , wherein the oral care composition is a dentifrice.9. A method for treating or preventing calculus formation in the oral cavity claim 1 , which comprises contacting the oral cavity with the oral care composition of .10Magnolia. A method of preventing inhibition of oral uptake of a antibacterial agent from an oral care composition of comprising formulating the oral care composition without phosphate-containing anticalculus agents or polyphosphate-containing anticalculus agents. The present invention relates to oral care compositions and methods employing such compositions for use in treating or preventing calculus formation.Dental plaque is a soft deposit which forms on the surfaces of teeth. Dental plaque is generally believed to be formed as a byproduct of bacterial ...

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Номер записи: 33
23-05-2013 дата публикации

Methods And Compositions For The Treatment Of Open And Closed Wound Spinal Cord Injuries

Номер: US20130129796A1
Автор: Langer Robert S., Saigal Rajiv, Teng Yang
Принадлежит:

Devices and methods for the treatment of open and closed wound spinal cord injuries are disclosed. For example, described herein are devices and methods for mitigating secondary injury to, and promoting recovery of, spinal cord primary injuries. More particularly, certain embodiments of the present invention are directed to polymeric mini-tubes that may be used for the treatment of spinal cord injuries. In addition, other embodiments are directed to polymeric “fill-in” bandages that may be used for the treatment of spinal cord injuries. For example, an erodible, or biodegradable, form of biocompatible polymer of the present invention is fabricated for surgical implantation into the site of the spinal cord injury. 1. A biodegradable and/or bioabsorbable polymeric tubular article suitable for treating a spinal cord injury in an animal , wherein the article comprises a biodegradable and/or bioabsorbable linear aliphatic polyester.2. The polymeric tubular article of claim 1 , wherein the linear aliphatic polyester is a polyglycolide or a copolymer poly(glycolide-co-lactide).3. The polymeric tubular article of claim 1 , comprising poly(lactic-co-glycolic acid).4. The polymeric tubular article of claim 1 , comprising poly(lactic-co-glycolic acid)-polylysine.5. The polymeric tubular article of claim 1 , comprising a blend of (1) poly(lactic-co-glycolic acid) and (2) a block copolymer of poly(lactic-co-glycolic acid)-polylysine.6. The polymeric tubular article of claim 1 , comprising a 50:50 blend of (1) poly(lactic-co-glycolic acid) and (2) a block copolymer of poly(lactic-co-glycolic acid)-polylysine.7. The polymeric tubular article of claim 6 , wherein the (1) poly(lactic-co-glycolic acid) is 75% poly(lactic-co-glycolic acid) and has an average molecular weight of Mn ˜40 claim 6 ,000.8. The polymeric tubular article of claim 6 , wherein the (2) block copolymer of poly(lactic-co-glycolic acid)-polylysine is 25% poly(lactic-co-glycolic acid)-polylysine copolymer and ...

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Номер записи: 34
30-05-2013 дата публикации

P-MENTHANE-3,8-DIOL ISOMER MIXTURE, COMPOSITION COMPRISING THE SAME, AND PRODUCTS COMPRISING THE MIXTURE OR COMPOSITION

Номер: US20130136704A1
Автор: Ishida Kenya, Komatsuki Yasuhiro, SHIROYAMA Kenichiro
Принадлежит: TAKASAGO INTERNATIONAL CORPORATION

An object of the present invention is to provide a novel technology for preventing crystal precipitation of p-menthane-3,8-diol, and stable products utilizing this technology. Provided is a p-menthane-3,8-diol isomer mixture, wherein the mass ratio of cis isomers:trans isomers in terms of the relative configuration at Positions 3 and 4 is 55:45 to 45:55. Also provided are stable products and the like containing the p-menthane-3,8-diol isomer mixture. 1. A p-menthane-3 ,8-diol isomer mixture , wherein the mass ratio of cis isomers:trans isomers in terms of the relative configuration at Positions 3 and 4 is 55:45 to 45:55.2. A composition obtained by mixing the p-menthane-3 claim 1 ,8-diol isomer mixture according to with an organic solvent.3. The composition according to claim 2 , whereinthe organic solvent is one or more selected from monoalcohols, polyols, ester oils, hydrocarbons, and silicone oils.4. The composition according to claim 2 , whereinthe mass ratio of the p-menthane-3,8-diol isomer mixture to the organic solvent is 90:10 to 30:70.5. The composition according to claim 2 , whereinthe organic solvent is a monoalcohol or polyol having 2 to 20 carbon atoms.6. An insect pest repellent composition claim 1 , comprising the p-menthane-3 claim 1 ,8-diol isomer mixture according to .7. The insect pest repellent composition according to claim 6 , further comprising at least one component selected from N claim 6 ,N-diethyl-m-toluamide claim 6 , 3-(N-n-butyl-N-acetyl)aminopropionic acid ethyl ester claim 6 , and 1-methylpropyl 2-(2-hydroxyethyl)-1-piperidinecarboxylate.8. A sensory stimulant composition claim 1 , comprising the p-menthane-3 claim 1 ,8-diol isomer mixture according to in combination with at least one component selected from menthol claim 1 , isopulegol claim 1 , menthone claim 1 , camphor claim 1 , pulegol claim 1 , cineol claim 1 , mint oil claim 1 , 3-menthoxypropane-1 claim 1 ,2-diol claim 1 , N-alkyl-p-menthane-3-carboxamide claim 1 , 3-menthoxy ...

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Номер записи: 35
06-06-2013 дата публикации

ORAL CARE PRODUCT AND METHODS OF USE AND MANUFACTURE THEREOF

Номер: US20130142736A1
Автор: Kohli Rajnish, Robinson Richard Scott, Sullivan Richard J.
Принадлежит: Colgatge-Palmolive Company

Described herein, are compositions comprising an effective amount of a basic amino acid in free or salt form, and a water soluble strontium salt; and methods of making and using the same. 1. An oral care composition comprisinga. an effective amount of a basic amino acid, in free or salt form; andb. an effective amount of a water soluble strontium salt.2. The oral care composition according to wherein the basic amino acid is arginine claim 1 , or a salt thereof.3. The oral care composition of claim 1 , wherein the water soluble strontium salt is selected from strontium acetate; strontium chloride; strontium nitrate; strontium lactate; strontium bromide; and a combination of two or more thereof.4. The oral care composition of further comprising a fluoride ion source.5. The oral care composition according to wherein the fluoride ion source is selected from sodium monofluorophosphate; stannous fluoride; sodium fluoride; potassium fluoride; sodium fluorosilicate; ammonium fluorosilicate; amine fluoride; ammonium fluoride; and a combination of two or more thereof.6. The oral care composition of in the form of a dentifrice.7. The oral care composition of in the form of a mouth rinse.8. The oral care composition of claim 1 , further comprising a potassium ion source.9. The oral care composition of claim 8 , wherein said potassium ion source is selected from potassium nitrate and potassium chloride.10. The oral care composition of claim 1 , further comprising a strontium-glass complex.11. The oral care composition of claim 10 , wherein the strontium-glass complex comprises strontium sodium phosphosilicate.13. A method for promoting systemic health comprising applying an effective amount of the oral composition of to a surface of the oral cavity of a subject in need thereof.14. An oral care composition according to claim 1 , for use in:a. reducing or inhibiting formation of dental caries,b. reducing, repairing or inhibiting early enamel lesions,c. reducing or inhibiting ...

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Номер записи: 36
13-06-2013 дата публикации

Personal care and medicinal products incorporating orgnosulfur groups

Номер: US20130149256A1
Автор: Ott David Michael
Принадлежит:

Personal care products useful for the maintenance of personal appearance and good health and minor treatments that do not require professional health care, as well as products that provide a combination of anti-microbial, anti-oxidant, anti-inflammatory, and anti-aging properties and are suitable for use without a prescription. The products utilize a biomembrane permeable organosulfur compound that can redox cycle between thiol, disulfide, and thiosulfinate forms in response to oxidants and antioxidants inside and outside of cells. Example products include an anti-microbial toothpaste with anti-plaque properties, an anti-inflammatory skin lotion with antioxidant, antimicrobial, and deodorant properties, and an anti-toxin skin lotion with anti-arsenicosis properties. 119-. (canceled)20allium. An anti-plaque oral care dentifrice composition comprising a membrane permeable related compound selected from the group consisting of allyl mercaptan , n-propyl mercaptan , diallyl disulfide , di-n-propyl disulfide. n-propyl allyl disulfide and combinations thereof , mixed with an orally acceptable carrier suitable for application to the teeth.221allium. The composition of claim where said membrane permeable related compound is allyl mercaptan.231allium. The composition of claim where said membrane permeable related compound is diallyl disulfide.24. The composition of where said diallyl disulfide is the diallyl disulfide of garlic oil.251allium. The composition of claim where said membrane permeable related compound is di-n-propyl disulfide.26. The composition of where said di-n-propyl disulfide is the di-n-propyl disulfide of onion oil.27allium. A method of making an anti-plaque oral care dentifrice composition comprising mixing a membrane permeable related compound selected from the group consisting of allyl mercaptan claim 25 , n-propyl mercaptan claim 25 , diallyl disulfide claim 25 , di-n-propyl disulfide. n-propyl allyl disulfide and combinations thereof claim 25 , with ...

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Номер записи: 37
13-06-2013 дата публикации

RAPIDLY DISSOLVING COMESTIBLE SOLID

Номер: US20130149258A1
Автор: Carroll Thomas J., Kumiega Steven M.
Принадлежит: THE HERSHEY COMPANY

A rapidly dissolving comestible solid is disclosed that includes a fondant formed from a super saturated solution having a bulk sweetener, a hydrocolloid, a texturizing agent, and water. Other ingredients may also be added, and in embodiments in which the solid is provided as a breath freshener, flavoring agents, cooling agents and/or other ingredients useful in conventional breath freshening products may be used. A method for making the comestible solid is also disclosed. 1. A rapidly dissolving comestible solid comprising a fondant formed of a bulk sweetener , a texturizing agent and , optionally , a hydrocolloid , wherein the fondant has a crystalline structure that does not exhibit cold flow at room temperature.2. The comestible solid of claim 1 , wherein the fondant is a super saturated solution that has a pre-cooking composition of about 68% to about 75% by weight bulk sweetener claim 1 , about 15% to about 25% by weight texturizing agent claim 1 , up to about 3.0% by weight hydrocolloid claim 1 , and up to about 10% by weight water.3. The comestible solid of claim 1 , further comprising flavoring agents claim 1 , sensates claim 1 , or combinations thereof.4. The comestible solid of claim 1 , wherein the comestible solid has a post-processing moisture content of about 3% to about 6% by weight.5. The comestible solid of claim 1 , wherein the comestible solid has a post-processing water activity in the range of about 0.40 to about 0.67.6. The comestible solid of claim 1 , wherein the comestible solid has a post-processing water activity in the range of about 0.50 to about 0.60.7. The comestible solid of claim 1 , wherein the bulk sweetener comprises xylitol.8. The comestible solid of claim 1 , wherein the hydrocolloid comprises a cellulose derivative.9. The comestible solid of claim 1 , wherein the texturizing agent comprises maltitol syrup.10. The comestible solid of claim 1 , wherein the bulk sweetener comprises xylitol claim 1 , the texturizing agent ...

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Номер записи: 38
27-06-2013 дата публикации

COMPOSITE PARTICLE ACTIVE AND METHOD FOR MAKING THE SAME

Номер: US20130164359A1
Автор: Deng Yan, Ding Guanjun, Li Xiaoke
Принадлежит:

Composite particle actives suitable for use in oral care compositions are described. The composite particle actives have a core and a coating whereby the coating interacts with phosphate ions to produce calcium and phosphate reaction products that are suitable to adhere to tooth enamel and/or dentin in order to improve characteristics of teeth. 1. A composite particle active comprising:a) a first component core for improving an oral care characteristic; andb) a second component coating that interacts with phosphate ions to produce a calcium phosphate in situ reaction product that adheres to tooth enamel, dentin or both and that is a precursor for hydroxyapatite formation.2. The composite particle active according to wherein the first component core comprises silica claim 1 , titanium dioxide claim 1 , zinc oxide claim 1 , mica claim 1 , calcium carbonate claim 1 , barium sulfate claim 1 , or a mixture thereof claim 1 , and the second component coating comprises elemental calcium claim 1 , and optionally claim 1 , potassium claim 1 , sodium claim 1 , aluminum claim 1 , magnesium or a mixture thereof.3. The composite particle active according to or wherein at least 5% of the first component core is coated with second component coating.4. The composite particle active according to any of the preceding claims wherein the composite particle active has a diameter of less than 50 microns.5. The composite particle active according to any of the preceding claims wherein the core of the composite particle active makes up from 3 to 98% by weight of the composite particle active.6. The composite particle active according to any of to wherein the first component core comprises at least 50% by weight titanium dioxide and the second component coating comprises at least 50% by weight calcium element.7. The composite particle active according to any of the preceding claims wherein the second component coating comprises calcium phosphate claim 1 , calcium gluconate claim 1 , calcium ...

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Номер записи: 39
25-07-2013 дата публикации

ANTIMICROBIAL DENTAL CARE PREPARATION

Номер: US20130189199A1
Автор: Geistlich Peter, Pfirrmann Rolf W.
Принадлежит: Geistlich Pharma AG

A dental care preparation in a form of a toothpaste or tooth gel dentifrice includes an antimicrobial amount of at least one antimicrobial N-methylol transfer agent, and at least one of a fluoride compound or a source of fluoride ions. 1. A dental care preparation in a form of a toothpaste or tooth gel dentifrice comprising an antimicrobial amount of at least one antimicrobial N-methylol transfer agent , and at least one of a fluoride compound or a source of fluoride ions.2. The dental care preparation of claim 1 , wherein at least a portion of said N-methylol transfer agent is dissolved in said preparation.3. The dental care preparation of claim 1 , wherein at least a portion of said N-methylol transfer agent is dispersed in said preparation as at least one of a microcrystalline claim 1 , a crystalline claim 1 , or a powder form.4. The dental care preparation of claim 2 , wherein at least a portion of said N-methylol transfer agent is further dispersed in said preparation as at least one of a microcrystalline claim 2 , a crystalline claim 2 , or a powder form.5. The dental care preparation of claim 1 , wherein said N-methylol transfer agent is taurolidine claim 1 , taurultam claim 1 , 1183B (cyclo-taurolidine) claim 1 , N-methylol taurinamide claim 1 , an N-methylol-containing and N-methylol transferring derivative thereof claim 1 , or any combination thereof.6. The dental care preparation of wherein said N-methylol transfer agent is taurolidine claim 1 , taurultam or a mixture thereof.7. The dental care preparation of wherein at least a portion of said agent is in microcrystalline claim 1 , crystalline or powder form.8. The dental care preparation of wherein the microcrystalline claim 7 , crystalline or powder form agent functions as an abrasive in said preparation.9. The dental care preparation of claim 1 , comprising about 0.01-10% by weight said N/methylol transfer agent.10. The dental care preparation of claim 1 , comprising about 0.1-5% by weight said N/ ...

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Номер записи: 40
25-07-2013 дата публикации

DENTINAL TUBULE SEALANT AND METHOD FOR PRODUCING THE SAME

Номер: US20130189337A1
Автор: HASHIMOTO Tadashi, ISHIHARA Shumei, Oshita Mizuko
Принадлежит: KURARAY NORITAKE DENTAL INC.

A dentinal tubule sealant comprises poorly-soluble calcium phosphate particles (A), a phosphorus-free calcium compound (B), and water (C), wherein the particles (A) are at least one member selected from the group consisting of dicalcium phosphate anhydrous [CaHPO] particles, α-tricalcium phosphate [α-Ca(PO)] particles, β-tricalcium phosphate [β-Ca(PO)] particles, amorphous calcium phosphate [Ca(PO).nHO] particles, calcium pyrophosphate [CaPO] particles, calcium pyrophosphate dihydrate [CaPO.2HO] particles, octacalcium phosphate pentahydrate [CaH(PO).5HO] particles, and dicalcium phosphate dihydrate [CaHPO.2HO] particles, and the dentinal tubule sealant contains 30 to 76% by weight of the particles (A), 0.001 to 4% by weight of the compound (B), and 23 to 69% by weight of the water (C). Thus, there is provided a dentinal tubule sealant capable of sealing dentinal tubules of an exposed dentin and also remineralizing the surrounding dentin after the sealing. 1. A dentinal tubule sealant , comprising:from 30 to 76% by weight of poorly-soluble calcium phosphate particles;from 0.001 to 4% by weight of a phosphorus-free calcium compound; andfrom 23 to 69% of water,{'sub': 4', '3', '4', '2', '3', '4', '2', '3', '4', '2', '2', '2', '2', '7', '2', '2', '7', '2', '8', '2', '4', '6', '2', '4', '2, 'wherein the poorly-soluble calcium phosphate particles are at least one member selected from the group consisting of a dicalcium phosphate anhydrous [CaHPO] particle, an α-tricalcium phosphate [α-Ca(PO)] particle, a β-tricalcium phosphate [β-Ca(PO)] particle, an amorphous calcium phosphate [Ca(PO).nHO] particle, a calcium pyrophosphate [CaPO] particle, a calcium pyrophosphate dihydrate [CaPO.2HO] particle, an octacalcium phosphate pentahydrate [CaH(PO).5HO] particle, and a dicalcium phosphate dihydrate [CaHPO.2HO] particle.'}2. The dentinal tubule sealant according to claim 1 ,{'sub': 2', '2', '3', '2', '2', '3', '2', '2', '2', '6', '10', '6', '3', '6', '5', '7', '2', '2', '3', '2', ...

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Номер записи: 41
01-08-2013 дата публикации

COLOR CHANGE OF CHALCONE-CONTAINING ORAL CARE FORMULATIONS

Номер: US20130195772A1
Автор: Du-Thumm Laurence, Schaeffer-Korbylo Lyndsay, Szewczyk Gregory
Принадлежит: Colgate-Palmolive Company

Oral care compositions and methods are described in which the composition includes a chalcone color change component, which may be phenyl-3-methoxy-4-hydroxystyryl ketone. The color change component is induced to change colors by addition of saliva and/or by a change in pH of the composition. The composition and methods provide benefits including providing visual cues to the user. 1. An oral care composition comprising a chalcone color change component that is able to change color by addition of saliva and/or by a change in pH of the composition.2. The oral care composition of claim 1 , wherein the color change component comprises phenyl-3-methoxy-4-hydroxystyryl ketone (CHAK4).3. The oral care composition of claim 1 , wherein the oral care composition is a mouthwash.4. The oral care composition of claim 2 , wherein the CHAK4 is present in an amount from 0.01% to 10% by weight of the composition.5. The oral care composition of claim 4 , wherein the CHAK4 is present in an amount from 0.01% to 0.05%.6. The oral care composition of claim 1 , wherein the pH of the composition is in the range of from 2 to 12.7. The oral care composition of claim 6 , wherein the pH of the composition is in the range of from 3.5 to 5.8. A mouthwash comprising a phenyl-3-methoxy-4-hydroxystyryl ketone in an amount from 0.01% to 10% by weight of the mouthwash.9. A method of making an oral care composition comprising a color change component comprising adding phenyl-3-methoxy-4-hydroxystyryl ketone (CHAK4) to an orally acceptable carrier.10. The method of claim 9 , wherein the CHAK4 is added in an amount from 0.01% to 10% by weight of the composition.11. The method of claim 9 , further comprising adjusting the pH to be within the range of from 3.5 to 5.0.12. A method of providing oral health benefits to an oral surface comprising contacting the oral surface according to with the oral care composition. This application claims priority to U.S. Provisional Patent Application No. 61/293,079, ...

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Номер записи: 42
01-08-2013 дата публикации

Processes Of Making Oral Compositions Containing Gel Networks

Номер: US20130195774A1
Автор: Deckner George Endel, Leblanc Michael Jude
Принадлежит: The Procter & Gamble Company

The present invention is directed towards a process for making oral compositions comprising gel networks. The gel networks are formed from a fatty amphiphile dispersion and swelling surfactant. The fatty amphiphile dispersion comprises one or more fatty amphiphiles, one or more dispersing surfactants, and one or more solvents. A gel network is formed when the fatty amphiphile dispersion is combined with the swelling surfactant. A method of preparing the fatty amphiphile dispersion and oral composition is included. 1. A process for preparing a dentifrice composition comprising: i) one or more fatty amphiphiles selected from the group consisting of cetyl alcohol and stearyl alcohol and combinations thereof;', 'ii) one or more dispersing surfactants selected from the group consisting of cetyl hydroxyl ethyl cellulose, inulin laryl carbamide, buylated polyvinylpyrrolidone, and combination thereof;', 'iii) one or more solvents; and', 'iv) optionally, a suppressing material,', 'by heating and mixing the fatty amphiphile dispersion,, 'a) preparing a fatty amphiphile dispersion comprisingb) providing one or more swelling surfactants; andc) providing oral carrier materials,d) mixing said fatty amphiphile dispersion, swelling surfactants, and oral carrier materials to form a gel network in the dentifrice.2. The process for preparing a dentifrice composition according to whereini) the one or more fatty amphiphiles is present in an amount of from about 15% to about 60% by weight of the fatty amphiphile dispersion;ii) the one or more dispersing surfactants is present in an amount of from about 0.05% to about 5% by weight of the fatty amphiphile dispersion;iii) the one or more solvents is present in an amount of from about 35% to about 80% by weight of the fatty amphiphile dispersion; andiv) the suppressing material is present in an amount of from about 0% to about 10% by weight of the fatty amphiphile dispersion.3. A process for preparing an oral composition comprising the steps ...

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Номер записи: 43
01-08-2013 дата публикации

ABRASIVE SYSTEM FOR ORAL CARE COMPOSITIONS

Номер: US20130195942A1
Автор: Ibrahim Sayed, Prencipe Michael
Принадлежит: Colgate-Palmolive Company

Oral compositions comprising a first and a second abrasive are provided. The first abrasive preferably has an Einlehner hardness of greater than about 5 mg loss per 100,000 revolutions, and the second abrasive preferably has an Einlehner hardness of less than about 5 mg loss per 100,000 revolutions. A ratio of the first abrasive to the second abrasive ranges from about 1:1.6 to about 1.6:1, and the first and second abrasives are preferably present in the oral composition at an amount of about 13% to about 21% by weight, respectively. The pellicle cleaning ratio of the oral composition is greater than 100 and the radioactive dentin abrasiveness is preferably less than 200, and in certain embodiments, preferably less than about 175. Methods of using the oral compositions are also provided. 2. The composition according to claim 1 , wherein the radioactive dentin abrasion is less than about 175.3. The composition according to claim 1 , wherein the first abrasive has an oil of absorption of less than about 90 cm/100 g and the second abrasive has an oil of absorption of greater than about 90 cm/100 g.4. The composition according to claim 1 , wherein the first abrasive has a mean particle size of less than about 11 μm and the second abrasive has a mean particle size of greater than about 8 μm.5. The composition according to claim 1 , wherein the ratio of the first abrasive to the second abrasive is about 1:1.6. The composition according to claim 5 , wherein the first abrasive is present in an amount of about 17% by weight and the second abrasive is present in an amount of about 17% by weight in the oral composition.7. The composition according to claim 1 , wherein a total amount of the first and second abrasives in the oral composition is greater than about 30% by weight of the composition.8. The composition according to claim 1 , wherein the first abrasive is present in an amount of about 13% to about 21% by weight and the second abrasive is present in an amount of about ...

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Номер записи: 44
08-08-2013 дата публикации

ORAL CARE COMPOSITIONS

Номер: US20130202539A1
Автор: "DAgostino Eleanor Margaret", Hedges Nicholas David, Nandi Asish, Petkov Jordan Todorov
Принадлежит:

The invention provides an oral care composition obtainable by: (i) preparing an oil-in-water emulsion by dispersing an oil phase into an aqueous continuous phase, the aqueous continuous phase comprising an oil-in-water emulsifier which is selected from one or more hydrophobins, so that emulsified particles of oil phase are formed which are emulsified with the one or more hydrophobins; and (ii) combining the emulsion so obtained with an oral care base formulation which is suitable for treating the surfaces of the oral cavity. Compositions of the invention demonstrate enhanced deposition of oil phase components onto oral cavity surfaces such as tooth enamel and tooth dentine, and in particular onto damaged surfaces such as scratched and demineralised enamel. 1. An oral care composition obtainable by:(i) preparing an oil-in-water emulsion by dispersing an oil phase into an aqueous continuous phase, the aqueous continuous phase comprising an oil-in-water emulsifier which is selected from one or more hydrophobins, so that emulsified particles of oil phase are formed which are emulsified with the one or more hydrophobins; andii) combining the emulsion so obtained with an oral care base formulation which is suitable for treating the surfaces of the oral cavity.2. An oral care composition according to claim 1 , where the hydrophobin is a Class II hydrophobin.3. An oral care composition according to claim 2 , where the Class II hydrophobin is HFBI claim 2 , HFBII claim 2 , or a mixture thereof.4. An oral care composition according to claim 1 , in which the oil phase comprises (i) a mixture of medium chain saturated fatty acids ranging from caproic to lauric (Cto C) claim 1 , in their triglyceride form claim 1 , and (ii) one or more long chain unsaturated fatty acid (Cto C) monoglycerides.5. An oral care composition according to claim 1 , in which the aqueous continuous phase (into which the oil phase is dispersed) comprises less than 0.01% anionic surfactant (by total weight ...

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Номер записи: 45
15-08-2013 дата публикации

Oral care compositions

Номер: US20130209376A1
Автор: Robert J. Corring, William E. Prosise
Принадлежит: IPS Investments Inc

Oral care compositions containing an oral care ingredient and a thickening agent, wherein the thickening agent comprises a strongly swellable, lightly to moderately crosslinked polyvinyl pyrrolidone. The polyvinyl pyrrolidone thickening agent is characterized by an aqueous gel volume of about 15 to 150 ml/g and a Brookfield viscosity of at least 10,000 cps for a 5% aqueous solution at 25° C.

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Номер записи: 46
15-08-2013 дата публикации

APPLICATIONS OF PARTIALLY AND FULLY SULFATED HYALURONAN

Номер: US20130209531A1
Автор: KENNEDY Thomas P., Oottamasathien Siam, Prestwich Glenn D.
Принадлежит: UNIVERSITY OF UTAH RESEARCH FOUNDATION

Described herein is the use of partially and fully sulfated hyaluronan or the pharmaceutically acceptable salt or ester thereof for therapeutic and cosmetic applications as well as the treatment of a number of systemic, dermatological, periodontal, ophthalmic, and urological inflammatory diseases. 1. A method for reducing or preventing inflammation in a subject comprising administering to the subject an effective amount of a partially or fully sulfated hyaluronan or the pharmaceutically acceptable salt or ester thereof , or a combination thereof.2. The method of claim 1 , wherein at least one primary C-6 hydroxyl proton of the N-acetyl-glucosamine residue is substituted with a sulfate group.3. The method of claim 1 , wherein at least 1% of the primary C-6 hydroxyl protons of the N-acetyl-glucosamine residue of hyaluronan are substituted with a sulfate group.4. The method of claim 1 , wherein from 1% to 100% of the primary C-6 hydroxyl protons of the N-acetyl-glucosamine residue of hyaluronan are substituted with a sulfate group.5. The method of claim 1 , wherein at least one C-2 hydroxyl proton or C-3 hydroxyl proton of a uronic acid residue or at least one C-4 hydroxyl proton of an N-acetyl-glucosamine residue is substituted with a sulfate group.6. The method of claim 1 , wherein at least one C-2 hydroxyl proton and C-3 hydroxyl proton of a uronic acid residue and at least one C-4 hydroxyl proton of an N-acetyl-glucosamine residue is substituted with a sulfate group.7. The method of claim 1 , wherein the compound has a degree of sulfation from 0.1 to 4.0 per disaccharide unit.8. The method of claim 1 , wherein the partially or fully sulfated hyaluronan has an average molecular size of less than 10 kDa.9. The method of claim 1 , wherein the partially or fully sulfated hyaluronan has an average molecular size from 0.5 kDa to 10 kDa.10. The method of claim 1 , wherein the hyaluronan is not derived from an animal source.11. The method of claim 1 , wherein the ...

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Номер записи: 47
22-08-2013 дата публикации

Dentifrice Composition with Reduced Astringency

Номер: US20130216485A1
Автор: Campbell Thomas S., Fisher Steven W., Prencipe Michael
Принадлежит: Colgate-Palmolive Company

A dentifrice composition containing, in combination, an orally acceptable vehicle; a halogenated diphenyl ether; a soluble zinc salt; and a chelating agent to reduce astringency. 1. A dentifrice composition comprising:a. an orally acceptable vehicle;b. a halogenated diphenyl ether;c. a soluble zinc salt; andd. a chelating agent, wherein the chelating agent is at least one chelating agent chosen from polyvinyl phosphonates, and phytates, wherein the chelating agent is present in an amount up to 1% based on the weight of the composition.218-. (canceled)19. The composition of claim 1 , wherein the chelating agent comprises dodecasodium phytate or sodium phytate.20. The composition of claim 19 , wherein the soluble zinc salt is present in an amount of 0.5 to 2.5 wt % based on the weight of the composition.2120. The composition of claim 19 , wherein the soluble zinc salt comprises at least one zinc salt chosen from zinc citrate claim 19 , zinc acetate claim 19 , zinc lactate claim 19 , zinc chloride claim 19 , and zinc gluconate.2221. The composition of claim 19 , wherein the soluble zinc salt comprises zinc citrate.23. The composition of claim 21 , whereinthe chelating agent is present in an amount of 0.1 to 1 wt % based on the weight of the composition.24. The composition of claim 23 , wherein the halogenated diphenyl ether is triclosan.25. The composition of claim 24 , wherein the dentifrice composition further comprises stannous fluoride and a methyl vinyl ether/maleic anhydride copolymer having a molecular weight ranging from 30 claim 24 ,000 to 1 claim 24 ,000 claim 24 ,000 g/mole.26. A method for the treatment and prevention of bacterial plaque accumulation comprising: administering to the oral cavity a dentifrice composition according to . Zinc ions are known to be effective anti-microbial agents. These ions provide anti-gingivitis and anti-plaque benefits and may also improve breath and reduce sensitivity. In particular, zinc has been shown to have anti-plaque, ...

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Номер записи: 48
29-08-2013 дата публикации

Liquid non-stick toothpaste

Номер: US20130224124A1
Автор: Douglas Bonnie Carol
Принадлежит:

My tooth cream will not stick, this is what makes it different from other tooth pastes. It can be dispensed in any type container, but it is different in that this toothpaste contains NO thickeners, no carrageenan, no cellulose gum, no glycerin and no SLS (sodium lanyl sulfates). My tooth créme can contain colorings, flavorings, preservatives, xylitol, sweetenings, fluoride . . . infinity. 1. A toothpaste (cream, wash, etc.) that is non-stick, will not stick to any surface, including but not limited, hair, clothing, sinks, floors, towels, rugs, walls . . . to infinity. The important aspect of my invention is the formula has a reduction or near elimination of the standard toothpaste formula—of certain additives that make toothpaste stiff, cement-like and sticky. My formula reduces or eliminates thickness—carrageenan, cellulose gum, glycerin, in any amount and various degrees, enough of a reduction in these elements to render the tooth “paste” liquid.The toothpaste of this invention is a toothpaste that has a reduction or near elimination of certain additives that make standard toothpaste stiff, cement-like and sticky. The toothpaste formula reduces or eliminates carrageenan, cellulose gum, glycerin, in any amount and various degrees, enough of a reduction in these elements to render the tooth “paste” liquid.My formula will be in liquid form, with/without abrasives, with/without SLS, can include colorings, flavorings, preservatives, sorbital, water, xylitol, sweeteners, fluoride, etc.This new “toothpaste” formula will be sanitary—multiple users will not need to touch the dispenser with their toothbrush because the formula will need to be dispersed in a pump-like dispenser similar to that used with soft soap. There will be no spreading of germs.Due to the softer, more liquid form of this toothpaste, this will not stick to sinks, floors, clothing, hair , etc . . . etc . . . there will be no messy, daily cleanup from the sticky, cement like quality of regular toothpaste. ...

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Номер записи: 49
29-08-2013 дата публикации

Alcohol-free slightly-alcoholic oral care composition and a process for preparing same

Номер: US20130224125A1
Автор: Narayanan S. Kolazi, Robert J. Corring, William E. Prosise
Принадлежит: Individual

An aqueous, heat and cold stable, non-alcoholic or slightly-alcoholic microemulsion based antimicrobial mouthwash composition with improved antimicrobial efficacy. The composition comprises a unique water-soluble matrix composite, at least one water-immiscible or water-insoluble antimicrobial agent, and optionally, a preservative or preservative system, a weak carboxylic acid, a coloring agent and other additives. Examples of antimicrobial agents include menthol, thymol, eucalyptol and/or methyl salicylate. A process for preparing the oral care composition is also disclosed.

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Номер записи: 50
29-08-2013 дата публикации

Oral Care Product and Methods of Use and Manufacture Thereof

Номер: US20130224126A1
Автор: Arvanitidou Evangelia S., Cuiule Christine, Dillon Rensl, Lewus Catherine, Mello Sarita, Nesta Jason, Smith-Webster Kimdra, Szewczyk Gregory
Принадлежит: Colgate-Palmolive Company

This invention relates to a mouthwash comprising an aqueous solution of an effective amount of a basic amino acid, in free or salt form together with an effective amount of a preservative selected from methylisothiazolinone (MIT), benzyl alcohol, phenoxyethanol, and combinations thereof; as well as to methods of using and of making such compositions. 1. A mouthwash comprising an aqueous solution ofa. an effective amount of a basic amino acid, in free or salt form;b. an effective amount of a preservative selected from methylisothiazolinone (MIT), benzyl alcohol, phenoxyethanol, and combinations thereof.2. The mouthwash of wherein the basic amino acid is arginine or a salt thereof.3. The mouthwash of wherein the basic amino acid is present in an amount corresponding to 0.01 to 2 wt. % of the total composition weight claim 1 , the weight of the basic amino acid being calculated as free base form.4. The mouthwash of wherein the preservatives are present claim 1 , separately or in combination claim 1 , in amounts as follows:a. MIT: 0.0005-0.03 wt. %b. benzyl alcohol: 0.05-0.25 wt. %c. phenoxyethanol: 0.1-0.7 wt. %.5. A mouthwash according to further comprising a pyrophosphate.6. A mouthwash according to further comprising a synthetic anionic polymeric polycarboxylate.7. A mouthwash according to further comprising a fluoride ion source.8. A mouthwash according to wherein the mouthwash is ethanol-free.9. A mouthwash according to further comprising one or more of humectants claim 1 , flavorings claim 1 , and surfactants.10. A mouthwash according to wherein the preservative comprises an amount effective to provide microbial control.11. A method to improve oral health comprising applying an effective amount of the mouthwash of any of the preceding claims to the oral cavity of a subject in need thereof toa. reduce or inhibit formation of dental caries,b. reduce, repair or inhibit early enamel lesions,c. reduce or inhibit demineralization and promote remineralization of the ...

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Номер записи: 51
29-08-2013 дата публикации

Oral Care Composition Comprising Arginine and Calcium Carbonate

Номер: US20130224270A1
Автор: Robinson Richard, SIMON Eric
Принадлежит: Colgate-Palmolive Company

This invention relates to oral care compositions comprising a basic amino acid or salt thereof, and an abrasive system comprising natural calcium carbonate and precipitated calcium carbonate; and to methods of using and of making these compositions. 2. The composition according to having precipitated calcium carbonate (PCC) having an average particle size of 1-5 microns.3. (canceled)4. The composition according to claim 1 , further comprising an effective amount of a fluoride source.5. The composition according to claim 1 , wherein the basic amino acid in free or salt form is arginine bicarbonate.6. The composition according to claim 1 , wherein the basic amino acid is present in an amount corresponding to 1% to 15% of the total composition weight claim 1 , the weight of the basic amino acid being calculated as free base form.7. (canceled)8. The composition according to wherein the ratio of natural calcium carbonate to precipitated calcium carbonate is from 1:2 to 1:3.9. The composition according to claim 1 , wherein the natural calcium carbonate is present in an amount of 5%-20% by weight of the composition and the precipitated calcium carbonate is present in an amount of 10% to 35% by weight of the composition.10. (canceled)11. The composition according to claim 9 , wherein the natural calcium carbonate is present in an amount of about 10% and the precipitated calcium carbonate is present in an amount of about 25% by weight of the composition.12. The composition according to claim 1 , further comprising an anionic surfactant.13. The composition according to claim 1 , further comprising an antibacterial agent.14. The composition according to claim 1 , further comprising an anionic polymer.15. The composition according to claim 1 , in the form of a toothpaste further comprising one or more of water claim 1 , abrasives claim 1 , surfactants claim 1 , foaming agents claim 1 , vitamins claim 1 , polymers claim 1 , enzymes claim 1 , humectants claim 1 , thickeners claim ...

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Номер записи: 52
29-08-2013 дата публикации

MICROBEADS FOR DENTAL USE

Номер: US20130224690A1
Автор: Karlinsey Robert L.
Принадлежит:

A method for decreasing dental hypersensitivity, including sizing a plurality of non-functionalized microbeads to be between 0.01 μm to 3 μm in diameter, suspending the plurality of non-functionalized microbeads in a fluid matrix to define a dental delivery composition, introducing the dental delivery composition into an oral cavity, introducing respective non-functionalized microbeads into a dental tubule, adhering respective functionalized microbeads each other and to the dental tubule to define an aggregate, and occluding the dental tubule with the aggregate. 1. A dental system , comprising:a dental matrix fluid; anda plurality of generally spherical non-functionalized metal oxide microbeads suspended in the dental matrix fluid;wherein each respective microbead is between about 0.01 micron and about 3 microns in diameter,2. The dental system of wherein the dental matrix fluid includes fluoride.3. The dental system of wherein the microbeads are silica.4. The dental system of wherein the microbeads are selected from the group including titania claim 1 , alumina claim 1 , silica claim 1 , and combinations thereof.5. A method for decreasing dental hypersensitivity claim 1 , comprising:a) selecting a plurality of non-functionalized microbeads;b) introducing the plurality of non-functionalized microbeads into the oral cavity;c) positioning respective non-functionalized microbeads into dental tubules; andd) occluding dental tubules with non-functionalized microbeads.6. The method of wherein the microbeads are generally composed of silica.7. The method of wherein each respective microbead is between 0.01 μm to 3 μm in diameter.8. The method of claim 5 , wherein the plurality of microbead is suspended in a dental vehicle claim 5 , wherein the dental vehicle is selected from the group comprising varnishes claim 5 , dentifrices claim 5 , mouthwashes claim 5 , and combinations thereof.9. A method for decreasing dental hypersensitivity claim 5 , comprising:{'b': '82', 'a) ...

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Номер записи: 53
05-09-2013 дата публикации

Oral Care Product and Methods of Use and Manufacture Thereof

Номер: US20130230469A1
Автор: Arvanitidou Evangelia S., Cuiule Christine, Dillon Rensl, Lewus Catherine, Mello Sarita, Nesta Jason, Smith-Webster Kimdra, Szewczyk Gregory
Принадлежит: Colgate-Palmolive Company

This invention relates to a mouthwash comprising an aqueous solution of an effective amount of an orally acceptable, soluble zinc salt together with an effective amount of a preservative selected from methylisothiazolinone (MIT), benzyl alcohol, glycerol monocaprylate, and combinations thereof; as well as to methods of using and of making such compositions. 1. A mouthwash comprising an aqueous solution ofa. an effective amount of an orally acceptable soluble zinc salt, wherein the zinc salt is present in an amount corresponding to 0.05 to 2 wt %; andb. an effective amount of a preservative selected from methylisothiazolinone (MIT), benzyl alcohol, glycerol monocaprylate, and combinations thereof.2. The mouthwash of wherein the zinc salt is zinc citrate.3. The mouthwash of wherein the preservatives are present claim 1 , separately or in combination claim 1 , in amounts as follows:a. MIT: 0.0005-0.1 wt. %b. benzyl alcohol: 0.05-0.25 wt. %c. glycerol monocaprylate: 0.01%-0.25 wt. %.4. A mouthwash according to further comprising a pyrophosphate.5. A mouthwash according to further comprising a synthetic anionic polymeric polycarboxylate.6. A mouthwash according to further comprising a fluoride ion source.7. A mouthwash according to which is ethanol-free.8. A mouthwash according to further comprising one or more of humectants claim 1 , flavorings claim 1 , and surfactants.9. A mouthwash according to wherein the preservative comprises an amount effective to provide microbial control.10. A method to improve oral health comprising applying an effective amount of the mouthwash of any of the preceding claims to the oral cavity of a subject in need thereof toa. reduce or inhibit formation of dental caries,b. reduce, repair or inhibit early enamel lesions,c. reduce or inhibit demineralization and promote remineralization of the teeth,d. reduce hypersensitivity of the teeth,e. reduce or inhibit gingivitis,f. promote healing of sores or cuts in the mouth,g. inhibit microbial ...

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Номер записи: 54
05-09-2013 дата публикации

PET FOOD COMPOSITION

Номер: US20130230470A1
Автор: KRAMMER Stephanie, PHEIFFER Joachim
Принадлежит: DSM IP ASSETS B.V.

Pet food comprising trisodium L-ascorbic acid-2-monophosphate (STAY-C50) or sodium-calcium L-ascorbic acid-2monophosphate (STAY-C35), or mixtures thereof and, optionally, a polymer (for fixation of the ascorbate on the dental surface) and use 5 thereof as additive to pet food for preventing or treating calculus, plaque, gingivitis and periodontal disease and for enhancing the antioxidative capacity in the whole organism. 110.-. (canceled)11. A method of treating gingivitis comprising the steps of:determining a dog or a cat in need of gingivitis treatment,administering or feeding said dog or cat a composition containing trisodium L-ascorbic acid-2-monophosphate in an amount of about 0.1% by weight to about 1% by weight to treat said gingivitis.12. A method of treating gingivitis comprising the steps of:determining a dog or a cat in need of gingivitis treatment,feeding to the dog or cat a pet food containing an effective amount of trisodium L-ascorbic acid-2-monophosphate to treat said gingivitis,wherein the trisodium L-ascorbic acid-2-monophosphate is present in the pet food in a concentration of between about 0.1% by weight to about 1% by weight.13. A method for treating gingivitis comprising the steps of:feeding to a dog or cat a pet food containing an effective amount of trisodium L-ascorbic acid-2-monophosphate to treat said gingivitis,wherein the trisodium L-ascorbic acid-2-monophosphate is present in a concentration of between about about 0.1% by weight to about 1% by weight and also present in the pet food is a polymer for improving the uptake and retention of trisodium L-ascorbic acid-2-monophosphate in an oral cavity and on tooth surfaces.14. A method as in wherein the polymer is present in an amount of from about 0.01% by weight to about 10% by weight claim 13 , based on the total weight of the pet food.15. A method as in wherein the polymer is a natural polymer or a derivative thereof claim 13 , or a synthetic polymer.16. A method as in wherein the polymer ...

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Номер записи: 55
05-09-2013 дата публикации

MEDICAL MATERIAL FOR IN VIVO IMPLANTATION CONTAINING SOFTENING AGENT AND/OR MOISTURIZING AGENT, METHOD FOR CONTROLLING CONTENT OF SOFTENING AGENT AND/OR MOISTURIZING AGENT IN THE MEDICAL MATERIAL, AND METHOD FOR PRODUCING THE MEDICAL MATERIAL FOR IN VIVO IMPLANTATION

Номер: US20130230638A1
Автор: NOISHIKI Yasuharu
Принадлежит:

A medical material for in vivo implantation contains a bioabsorbable material containing a softening agent and/or a moisturizing agent and a non-bioabsorbable porous base material, in which the content of a softening agent and/or a moisturizing agent is controlled less than 20 wt %; a method for controlling this content; and a method for producing a medical material for in vivo implantation are provided. 1. A method for preparation of a medical material for in vivo implantation comprising a bioabsorbable material which contains a softening agent and/or a moisturizing agent and a non-bioabsorbable porous substrate comprising, adjusting content of said softening agent and/or moisturizing agent to less than 20 weight % to the total weight of said medical material by washing said medical material with a solvent of said softening agent and/or moisturizing agent or by impregnating said medical material in the solvent. The present invention relates to a hybrid medical material for in vivo implantation, which is used for surgical operation of blood vessel, trachea, blood vessel wall, heart wall, pericardium, chest wall or peritoneum, comprising a bioabsorbable material and a non-bioabsorbable porous substrate. Especially, in a case when large amount of a softening agent and/or a moisturizing agent (can be shortened simply as softening agent) are contained in said medical material for in vivo implantation, a phenomenon of retention of exudates to a circumference of the medical material causes. In the present invention, the inventor of the present invention indicate that the reason of the phenomenon is a side effect of the softening agent and/or moisturizing agent, and for the purpose to suppress the side effect, the inventor accomplish the present invention. That is, the present invention relates to a medical material for in vivo implantation whose content of the softening agent and/or moisturizing agent is minimized as small as possible, a method to adjust the content of ...

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Номер записи: 56
12-09-2013 дата публикации

Oral Care Product and Methods of Use and Manufacture Thereof

Номер: US20130236400A1
Автор: Arvanitidou Evangelia S., Cuiule Christine, Dillon Rensl, Lewus Catherine, Mello Sarita, Nesta Jason, Smith-Webster Kimdra, Szewczyk Gregory
Принадлежит: Colgate-Palmolive Company

This invention relates to a dual phase mouthwash comprising a hydrophilic phase, a hydrophobic phase, and a hydrotrope, wherein the hydrophilic phase comprises an effective amount of a preservative selected from methylisothiazolinone, sodium benzoate, potassium sorbate, and combinations thereof, as well as to methods of using and of making such compositions. 1. A dual phase mouthwash comprisinga hydrophilic phase, a hydrophobic phase, a hydrotrope, and a preservative wherein the preservative comprises (i) sodium benzoate and (ii) potassium sorbate and/or methylisothiazolinone and wherein the mouthwash comprises (a) 0.05%-0.5% sodium benzoate and (b) 0.05%-0.2% potassium sorbate and/or 0.0005%-0.01% MIT.2. The mouthwash of wherein the hydrotrope component comprises glycerin and/or propylene glycol.3. The mouthwash of wherein the hydrophobic phase comprises an oil selected from isopropyl myristate claim 1 , mineral oil claim 1 , an edible oil claim 1 , and combinations thereof.4. The mouthwash of wherein the hydrophilic phase comprises the hydrotrope component.5. The mouthwash of wherein the hydrophilic phase further comprises cetylpyridinium chloride claim 1 , e.g. claim 1 , in an amount of from 0.01-0.1% claim 1 , e.g. claim 1 , 0.05%.6. The mouthwash of further comprising a pyrophosphate.7. The mouthwash of further comprising a synthetic anionic polymeric polycarboxylate.8. The mouthwash of further comprising a fluoride ion source.9. The mouthwash of which is ethanol-free.10. The mouthwash of further comprising one or more of humectants claim 1 , flavorings claim 1 , and surfactants.11. The mouthwash of wherein the hydrophilic phase comprises an effective amount of the preservative.12. A method to improve oral health comprising applying an effective amount of the mouthwash of any of the preceding claims to the oral cavity of a subject in need thereof toa. reduce or inhibit formation of dental caries,b. reduce, repair or inhibit early enamel lesions,c. reduce or ...

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Номер записи: 57
12-09-2013 дата публикации

Oral health care material and teeth cleaning agent composition

Номер: US20130236519A1
Автор: Chang Hsin-Ju, Lu Hung-Ching, SHIEH Dar-Bin
Принадлежит: NATIONAL CHENG KUNG UNIVERSITY

An oral health care material and a teeth cleaning agent composition are disclosed. The oral health care material is made of zinc oxide grains, where each is selected from the group consisting of zinc oxide crystalline nanograins, zinc oxide nanorods, zinc oxide hollow fibers, and a mixture thereof, wherein the diameter of each of the zinc oxide crystalline nanograins is 25 nm-200 nm, the cross-sectional diameter of each of the zinc oxide nanorods is 50 nm-1000 nm, the cross-sectional diameter of each of the zinc oxide hollow fibers is 500 nm-3 μm and its nanograin size is 20 nm-100 nm. 1. An oral health care material which comprises zinc oxide (ZnO) grains , each zinc oxide grain is selected from the group consisting of crystallized ZnO nanograins , crystallized ZnO nanorods , nano-ZnO hollow fibers , and a combination thereof;wherein each of the crystallized ZnO nanograins has a diameter of 25 nm-200 nm, each of the crystallized ZnO nanorods has a cross-sectional diameter of 50 nm-1000 nm, each of the nano-ZnO hollow fibers has a tube-like structure, and each of the nano-ZnO, hollow fibers has a cross-sectional diameter of 500 nm-3 μm.2. The oral health care material as claimed in claim I , wherein the each of the nano-ZnO hollow fibers is composed of plural ZnO nanograins.3. The oral health care material as claimed in claim 2 , wherein the each ZnO nanograin has a diameter of 20 nm-100 nm.4. The oral health care material as claimed in claim 1 , wherein the each of the crystallized ZnO nanograins is selected from the group consisting of single-crystallized ZnO grains claim 1 , poly-crystallized ZnO grains claim 1 , and a combination thereof.5. The oral health care material as claimed in claim 1 , wherein the each of the crystallized ZnO nanograins has a diameter of 50 nm-100 nm.6. The oral health care material as claimed in claim 1 , wherein the each of the crystallized ZnO nanorods has a cross-sectional diameter of 200 nm-500 nm.7. A teeth cleaning agent ...

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Номер записи: 58
12-09-2013 дата публикации

LICORICE LOLLIPOP THAT INHIBITS DENTAL CARIES FORMATION

Номер: US20130236527A1
Автор: Anderson Maxwell H.
Принадлежит: INTELLIHERB, LLC

This invention pertains to the discovery that certain extracts of licorice, particularly when formulated as a candy or lollipop or other means that provides an extended release (e.g., greater than about 4 minutes) to the oral cavity significantly inhibits the formation of dental caries in a human subject. 1Glycyrrhiza. A composition for reducing dental caries in a human subject , said composition comprising a lollipop or hard candy , wherein said lollipop or hard candy is substantially sugar free , and said lollipop or hard candy comprises an extract from the root of spp. , wherein said extract comprises a glycyrrhizol.2. The composition of claim 1 , wherein said lollipop or hard candy is a lollipop.3. The composition of claim 1 , wherein said lollipop or hard candy comprises:a starch or dextrin;a flavoring;a sweetener; andsaid extract.4. The composition of claim 3 , wherein said sweetener is non-cariogenic.5. The composition of claim 3 , wherein said sweetener is a sugar alcohol.6. The composition of claim 3 , wherein said sweetener is an artificial sweetener.7. The composition of claim 3 , wherein said sweetener is selected from the group consisting of stevia claim 3 , aspartame claim 3 , saccharin claim 3 , acesulfame k claim 3 , sucralose claim 3 , and neotame.8. The composition of claim 3 , wherein said lollipop or hard candy comprises:hydrogenated starch hydrolysate;citric acid;flavoring; andacesulfame potassium.9. The composition of claim 8 , wherein said lollipop or hard candy further comprises a coloring agent.10. The composition of claim 1 , wherein said extract comprises substantially purified glycyrrhizol A claim 1 , and/or substantially purified glycyrrhizol B claim 1 , and/or substantially purified 6 claim 1 ,8-diisoprenyl-5 claim 1 ,7 claim 1 ,4′-trihydroxyisoflavone.11. The composition of claim 10 , wherein said extract comprises substantially purified glycyrrhizol A.12. The composition of claim 1 , wherein said extract consists essentially of ...

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Номер записи: 59
12-09-2013 дата публикации

HARD TISSUE REGENERATION MATERIAL AND HARD TISSUE REGENERATION METHOD

Номер: US20130236856A1
Автор: HONTSU Shigeki, KUSUNOKI Masanobu, NISHIKAWA Hiroaki, YAMAMOTO Kazuyo, YOSHIKAWA Kazushi
Принадлежит: KINKI UNIVERSITY

Provided are a hard tissue restoration material, which is excellent in hard tissue restoration ability, extremely effective in promoting recalcification of dental enamel, and excellent in protection properties and aesthetic properties, and a hard tissue restoration method. The hard tissue restoration material according to the present invention is a biocompatible ceramic film with flexibility and pliability that is obtained, for example, by immersing a substrate, having the biocompatible ceramic film formed thereon, in a solvent, which does not dissolve the biocompatible ceramic but dissolves at least a portion of the substrate, to dissolve or separate the substrate. Also, with the hard tissue restoration method according to the present invention, the hard tissue restoration material according to the present invention is bonded to or wound around a hard tissue defect site. 1. A hard tissue restoration material with flexibility and pliability that is a biocompatible ceramic film obtained by forming the biocompatible ceramic film on a substrate that includes a portion that is removable under an environment in which a shape of the biocompatible ceramic film can be maintained and thereafter removing the substrate , on which the biocompatible ceramic film has been formed , under that environment.2. The hard tissue restoration material according to claim 1 , formed by laminating a plurality of biocompatible ceramic films.3. The hard tissue restoration material according to claim 1 , formed by laminating an apatite precursor on a surface of the biocompatible ceramic film.4. The hard tissue restoration material according to claim 3 , wherein the apatite precursor is anyone of monocalcium phosphate claim 3 , dicalcium phosphate claim 3 , tricalcium phosphate claim 3 , tetracalcium phosphate claim 3 , and octacalcium phosphate.5. The hard tissue restoration material according to claim 1 , wherein the biocompatible ceramic film is a film of an apatite selected from the group ...

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Номер записи: 60
19-09-2013 дата публикации

Mouthwash Composition for Managing Oral Mucositis, Process and Methods Thereof

Номер: US20130243702A1
Автор: Kumar Ravikumar Rejnish, Pillai Madhavan Radhakrishna, Ramadas Kunnambath, Ravindran Divya
Принадлежит:

The present disclosure is in relation to a herbal cleansing composition comprising extracts from five plants namely and . Further, the present disclosure also relates to a process of obtaining said composition and applications thereof, wherein the composition is preferably used as an oral wash for delaying the onset of oral mucositis in cancer patients undergoing radiation treatment. 1Emblica officinalis, Terminalia chebula, Terminalia bellerica, Glycyrrhiza glabraAzadiracta indica.. A composition comprising extracts of and2Emblica officinalisTerminalia chebulaTerminalia bellericaGlycyrrhiza glabraAzadiracta indica. The composition as claimed in claim 1 , wherein the extracts of the claim 1 , the and the are obtained from dried fruits of said species; and wherein the extract of the is obtained from root; and wherein the extract of the is obtained from combination of leaves and bark.3Emblica officinalis, Terminalia chebula, Terminalia bellerica, Glycyrrhiza glabraAzadiracta indica. A method for obtaining a composition comprising extracts of and claim 1 , said method comprising acts of:{'i': Emblica officinalis, Terminalia chebula, Terminalia bellerica, Glycyrrhiza glabra', 'Azadiracta indica, '(a) soaking plant parts of and in a solvent to obtain extract of the plant parts; and'}(b) decanting the extract to obtain the composition.4. The method as claimed in claim 3 , wherein the plant parts are soaked for about a period ranging from about 8 hr to about 14 hr.5. The method as claimed in claim 3 , wherein the concentration of each of the extracts is ranging from about 10% w/w to about 20% w/w.6. The method as claimed in claim 3 , wherein the solvent is selected from a group comprising of water claim 3 , ethyl alcohol claim 3 , carboxymethyl cellulose claim 3 , propylene glycol claim 3 , and glycerine.7Emblica officinalisTerminalia chebulaTerminalia bellericaGlycyrrhiza glabraAzadiracta indica.. The method as claimed in claim 3 , wherein the plant parts are dried fruits ...

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Номер записи: 61
19-09-2013 дата публикации

BREATH FRESHENING CONFECTIONERY PRODUCTS AND METHODS OF MAKING AND USING SAME

Номер: US20130243838A1
Автор: Clark James C., Haas Michael S., McGrew Gordon N., Mindak Thomas M., Soukup Philip M., Stawski Barbara Z.
Принадлежит: WM. WRIGLEY JR. COMPANY

A confectionery product comprises a first side and a second side generally opposite to said first side, and a product thickness. The second side comprises an abrasive surface that is suitable for cleaning the top surface of a tongue within an oral cavity. The second side has a width and a length, the smallest of which is at least 1.6 times the product thickness. The product does not include a handle and the product does not include a combination of a soft confectionery with a hard confectionery. In some embodiments the first side is smooth, and may be domed shaped and generally fit the roof of the mouth. The abrasive surface may be provided by 1) a formed, uneven surface, 2) including abrasive particles in the composition making up the second surface, or 3) a combination of a formed, uneven surface and abrasive particles. The confectionery product may be a hard confectionery, but may also be a chewing gum product. 1. A method of removing bacteria from the top surface of a human tongue comprising:a) placing a confectionery product having a first side and a second side generally opposite to said first side, and a product thickness, in an oral cavity, the second side comprising an abrasive surface and having a width and a length, the smallest of which is at least 1.6 times the product thickness, with the abrasive surface contacting the top surface of the tongue, wherein the product does not include a handle and wherein the product does not include a combination of a soft confectionery with a hard confectionery; andb) causing the abrasive surface of the confectionery product to be scraped across the top surface of the tongue while the oral cavity is closed to thereby loosen bacteria on the top surface of the tongue.2. The method of wherein the confectionery product has an abrasive surface provided by one or more of:a) abrasive particles in the confectionery of which the product is formed, andb) an uneven surface formed on the confectionery product.3. The method of ...

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Номер записи: 62
19-09-2013 дата публикации

IMPLANTABLE MATERIALS FOR BONE REPAIR

Номер: US20130244942A1
Автор: BENEDICT James J., Davis Katherine Suzanne, Hannigan Nolan Chase, Young Whitney Terese
Принадлежит: Cerapedics, Inc.

The invention features fiber reinforced bone repair putties and fiber reinforced pliable lyophilized implants which are useful for the treatment of bone defects. The putties and lyophilized implants include ceramic particles. The formulations of the invention can exhibit reduced migration of the ceramic particles, and are mechanically strengthened so the materials can be aggressively manipulated by a physician during an implantation procedure without tearing or puncturing. 1. A bone repair putty comprising:(i) from 25% to 65% (w/w) particulate bone graft substitute or particulate demineralized bone matrix having a mean particle size of from 100 μm to 1000 μm;(ii) from 30% to 75% (w/w) hydrogel carrier for suspending said particulate bone graft substitute; and(iii) from 0.2% to 2% (w/w) fibers, said fibers having an average length of from 0.5 to 15 mm,wherein said bone repair putty is non-setting and malleable and wherein the migration of said ceramic particles from said putty is reduced.2. The bone repair putty of claim 1 , wherein said hydrogel carrier comprises a dispersing agent selected from glycerin claim 1 , polyethylene glycol claim 1 , N-methylpyrrolidone claim 1 , and triacetin; a polymer selected from sodium carboxymethylcellulose claim 1 , polyvinylalcohol claim 1 , hydroxyethyl cellulose claim 1 , hydroxypropyl methylcellulose claim 1 , methylcellulose claim 1 , ethylcellulose claim 1 , and hyaluronic acid; and water.3. The bone repair putty of claim 2 , wherein said bone repair putty comprises:(i) from 3% to 10% (w/w) a dispersing agent selected from glycerin, polyethylene glycol, N-methylpyrrolidone, and triacetin;(ii) from 0.5% to 2.0% (w/w) a polymer selected from sodium carboxymethylcellulose, polyvinylalcohol, hydroxyethyl cellulose, hydroxypropyl methylcellulose, methylcellulose, ethylcellulose, and hyaluronic acid;(iii) from 40% to 60% (w/w) particulate calcium phosphate;(iv) from 25% to 55% (w/w) water; and(v) from 0.2% to 2% (w/w) fibers, said ...

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Номер записи: 63
26-09-2013 дата публикации

Dentifrice Compositions Containing Calcium Silicate

Номер: US20130251772A1
Автор: Chopra Suman Kumar, Patel Rahul
Принадлежит: Colgate-Palmolive Company

An oral care composition includes an effective amount of calcium silicate particles. The calcium silicate particles have an average diameter of less than about 5 microns, such that they can occlude dentinal tubules of the teeth. An oral care method includes applying the composition to an oral cavity of a subject to reduce or inhibit hypersensitivity of the teeth and to achieve other benefits. 1. An oral care composition comprising an effective amount of calcium silicate particles , wherein the calcium silicate particles have an average diameter of less than 5 microns , wherein the particles have a d50 of 2 μm to 5 μm , and a d90 of 5 μm to 10 μm , and a CVP 3.95 of at least 50%.2. (canceled)3. The composition according to wherein the calcium silicate has a pH between 8.4 and 11.2 in a 5% solution.4. The composition according to claim 1 , wherein the calcium silicate has a surface area 20-400 m2/g and a pore volume of 0.01-1 cc/g.5. The composition according to further comprising potassium salts.6. The composition according to claim 5 , wherein the potassium salts is present at a concentration of 1-10 wt. % based on a weight of the composition.7. The composition according to claim 1 , wherein the oral care composition provides a fluid flow rate of no greater than about 45% of the fluid flow rate of etched dentin.8. The composition according to claim 1 , wherein the effective amount of calcium silicate particles is 5-20 wt. % based on a weight of the composition.9. The composition according to claim 1 , wherein the average diameter of the calcium silicate particles is from 2 microns to 5 microns.10. The composition according to claim 1 , further comprising precipitated calcium carbonate or silica.11. The composition according to claim 1 , further comprising a soluble fluoride salt claim 1 , an anionic surfactant and an antibacterial agent.12. The composition according to claim 1 , wherein the composition is aqueous.13. A method to:reduce or inhibit formation of dental ...

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Номер записи: 64
26-09-2013 дата публикации

BIOHYBRID COMPOSITE SCAFFOLD

Номер: US20130253663A1
Автор: Amoroso Nicholas J., Badylak Stephen F., Hong Yi, HUBER Alexander, Takanari Keisuke, Wagner William R.
Принадлежит:

A biohybrid scaffold is provided that is useful in clinical applications for abdominal wall reconstruction, pelvic floor repair, breast reconstruction, as well as other soft tissue repairs. Methods of making and using the biohybrid scaffold are provided. 1. A method of making a biohybrid scaffold comprising electrospinning a biodegradable , biocompatible , elastomeric polymer composition onto a substrate and concurrently or substantially concurrently electrospraying an ECM-derived gel onto the substrate.2. The method of wherein the substrate is a mandrel.3. The method of wherein the biodegradable claim 1 , biocompatible elastomeric polymer comprises one or more of a poly(ester urethane)urea (PEUU) claim 1 , a poly(ether ester urethane)urea (PEEUU) claim 1 , a poly(ester carbonate)urethane urea (PECUU) and a poly(carbonate)urethane urea (PCUU).4. The method of in which the polymer comprises polycaprolactone.5. (canceled)6. The method of claim 4 , in which the polycaprolactone has an Mw of 1000-5000.7. (canceled)8. The method of in which the biodegradable claim 4 , biocompatible elastomeric polymer comprises a copolymer of polycaprolactone (Mw˜2000) claim 4 , 1 claim 4 ,4-diisocyanobutane and putrescine.9. (canceled)10. (canceled)11. The method of claim 1 , in which the biodegradable claim 1 , biocompatible elastomeric polymer is prepared from a polycaprolactone-polyethylene glycolpolycaprolactone triblock copolymer claim 1 , an aliphatic diisocyanate and an aliphatic diamine.12. The method of in which the aliphatic diisocyanate is 1 claim 11 ,4-diisocyanobutane and the aliphatic diamine is putrescine.13. The method of claim 1 , in which the polymer is prepared from an aliphatic diisocyanate and an aliphatic diamine.14. The method of claim 13 , in which the aliphatic diisocyanate is 1 claim 13 ,4-diisocyanobutane and/or the diamine is putrescine.15. The method of claim 1 , in which the ECM-derived gel is prepared from dermal ECM claim 1 , urinary bladder ECM and/or ...

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Номер записи: 65
03-10-2013 дата публикации

Stannous Salt and Sodium Tripolyphosphate Oral Care Compositions and Methods

Номер: US20130259810A1
Автор: Brown James R., Fruge Linh, Prencipe Michael, Xu Tao
Принадлежит:

Oral care compositions containing a stannous salt and sodium tripolyphosphate are provided where stannous tripolyphosphate ionic intermediates comprise less than about 1% of the compositions Tetrasodium pyrophosphate, a methylvinyl ether-maleic anhydride copolymer and/or a silica oral polishing agent may be added for further efficacy. In a single phase blend, the oral care composition may be effectively limited to comprise less than about 10% water. In a dual-phase blend, a mixture having the stannous salt in a first phase and the sodium tripolyphosphate in a second phase may be generated from a dual chamber storage tube (with each phase provided from a separate chamber) immediately prior to dental care usage. 2. The composition of claim 1 , comprising about 0.1 to about 3% stannous salt.3. The composition of claim 1 , comprising about 0.1 to about 10% sodium tripolyphosphate.4. The oral care composition of wherein the stannous salt is stannous fluoride.5. The composition of claim 1 , comprising less than 8% water.6. The composition of claim 1 , comprising less than 6% water.7. The composition of further comprising a compound chosen from tetrasodium pyrophosphate and a silica polishing agent.9. An oral care kit comprising a container containing a mixture of: (a) about 0.01 to about 5% stannous salt; (b) about 0.01 to about 15% sodium tripolyphosphate; (c) 10% or less by weight water; and (d) an orally acceptable carrier selected from the group consisting of adhesion agents claim 1 , viscosity modifiers claim 1 , diluents claim 1 , surfactants claim 1 , foam modulators claim 1 , peroxide activators claim 1 , peroxide stability agents claim 1 , abrasives claim 1 , pH modifying agents claim 1 , humectants claim 1 , mouth feel agents claim 1 , sweeteners claim 1 , flavorants claim 1 , colorants claim 1 , and combinations thereof;wherein the mixture comprises less than about 1% stannous tripolyphosphate ionic intermediates.10. The oral care kit of wherein the mixture ...

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Номер записи: 66
10-10-2013 дата публикации

Non-Aqueous Oral Care Composition Containing Dental Occlusion Actives

Номер: US20130263395A1
Автор: Boyd Thomas James, Chopra Suman Kumar, Mello Sarita Vera, Ontumi Dennis Kembero, Patel Rahul
Принадлежит: Colgate-Palmolive Company

A oral care composition includes: (a) a hydrophilic film-forming polymer; and (b) a hydrophobic carrier, wherein the hydrophilic film-forming polymer is a film-forming polymer effective to occlude dentinal tubules and the oral care composition contains 0-10 wt. % water. The hydrophilic film-forming polymer is preferably GANTREZ S. The hydrophobic carrier is preferably a vegetable oil. A method of cleaning teeth includes applying to the teeth the oral care composition such that the hydrophilic film-forming polymer occludes dentinal tubules. A toothbrush includes: a handle; a head mounted to the handle, the head comprising an outer surface and a plurality of tooth cleaning elements extending outwardly from the outer surface; and a gelatin capsule containing the oral care composition positioned on the head. 1. A oral care composition comprising:(a) a hydrophilic film-forming polymer; and(b) a hydrophobic carrier,wherein the polymer is effective to occlude dentinal tubules and the oral care composition contains less than 10 wt. % water,wherein the hydrophilic film-forming polymer constitutes 2-5 wt. % of the oral care composition and is an acid form of a copolymer of maleic anhydride,wherein the hydrophobic carrier constitutes 55-85 wt % of the oral compositions, andwherein the oral care compositions further comprises a polyphosphate.2. The oral care composition of claim 1 , wherein the oral care composition contains less than 1 wt. % water.3. (canceled)4. The oral care composition of claim 2 , wherein the hydrophobic carrier comprises at least one member selected from the group consisting of an oil claim 2 , a wax and silicone.5. The oral care composition of claim 4 , wherein the hydrophobic carrier comprises vegetable oil and/or silicone oil.6. The oral care composition of claim 5 , wherein the hydrophobic carrier comprises a C6 to C12 triglyceride.7. The oral care composition of claim 2 , wherein the polyphosphate is at least one member selected from the group ...

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Номер записи: 67
10-10-2013 дата публикации

Oral Compositions Comprising Propolis

Номер: US20130266521A1
Автор: Blanvalet Claude, Fetissova Nataly, Lambert Pierre
Принадлежит:

Oral compositions are provided that comprise a propolis extract; an oral care active compound chosen from: a cationic antibacterial agent, an anti-attachment agent, a biofilm disruption agent, and an anti-inflammatory agent; and a source of fluoride ions. Further, in certain embodiments, the oral composition comprises an anionic polymeric linear polycarboxylate. The oral composition can be in a form of a mouth rinse, a dentifrice, a confectionary, a medicament, or a film. Methods of making and using the oral compositions are also provided. 1. An oral composition comprising:a propolis extract;an oral care active compound chosen from: a cationic antibacterial agent, an anti-attachment agent, a biofilm disruption agent or an anti-inflammatory agent; anda source of fluoride ions.2. An oral composition according to claim 1 , wherein the propolis extract is present in an amount of about 0.0001 to about 3%.3. An oral composition according to claim 1 , further comprising a polyhydric compound and water.4. An oral composition according to claim 1 , wherein the propolis extract comprises one or more active compounds derived from a propolis source in an amount of about 1 to about 5% by weight of the propolis extract.5. An oral composition according to claim 1 , further comprising an anionic polymeric linear polycarboxylate.6. An oral composition according to claim 5 , wherein the anionic polymeric linear polycarboxylate is an anionic polymeric copolymer of methyl vinyl ether and maleic anhydride.7. An oral composition according to claim 1 , wherein the oral care active compound is a cationic antibacterial agent chosen from benzethonium chloride claim 1 , octenidine claim 1 , hexetidine claim 1 , hexamidine claim 1 , cetyl pyridinium chloride claim 1 , alexidine claim 1 , N-acyl amino acid alkyl ester salts or mixtures thereof.8. An oral composition according to claim 7 , wherein the oral care active compound is chosen from: N-cocoyl-L-arginine methyl ester claim 7 , N-cocoyl-L ...

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Номер записи: 68
10-10-2013 дата публикации

ALGAL EXTRACT-BASED COMPOSITION FOR ORO-DENTAL USE

Номер: US20130266522A1
Автор: Dutot Mélody, Fagon Roxane, Hemon Marc
Принадлежит: YS LAB

An algal extract-based composition for oro-dental use is provided. This composition comprising a mixture of algae with at least and spp, is characterized in that said mixture of algae has a proportion of of at least 90% of the weight of the mixture and that the proportion of spp. is at most 10% of the weight of the mixture, and in that said extract is combined with a natural surfactant and/or with a zeolite or a mixture of zeolites. Uses of said composition, in particular tot dental prevention and or care are also provided. Applications in the oro-dental field, both preventively and curatively. 1Ascophyllum nodosumFucusAscophyllum nodosumFucus. A composition for oro-dental use based on an extract of brown algae comprising a mixture of algae with at least and spp. which is characterized in that said mixture of algae has a proportion of of at least 90% of the weight of the mixture and that the proportion of spp is at most 10% of the weight of the mixture , and in that said extract is combined with at least one silver-loaded zeolite.2Ascophyllum nodosumFucus. The composition as claimed in claim 1 , characterized in that the mixture of and spp. is less than or equal to 1.5% of the weight of the composition and preferably from 0.1% to 1%.3. The composition as claimed in claim 1 , characterized in that a natural surfactant is present at less than or equal to 2% of the weight of the composition.4. The composition as claimed in claim 3 , characterized in that the natural surfactant is a sophorose lipid.5. The composition as claimed in claim 1 , characterized in that the zeolite or the mixture of zeolites is between 0.1% and 1% of the weight of the composition.6. The composition as claimed in claim 1 , characterized in that the zeolite or at least one zeolite is a mixture of silicon oxide and aluminum oxide.7. The composition as claimed in claim 1 , characterized in that it is combined with any excipient required for its galenical formation.8. The composition as claimed in ...

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Номер записи: 69
10-10-2013 дата публикации

Oral Compositions and Method for Producing Thereof

Номер: US20130266523A1
Автор: Gu Ben, Hassan Mahmoud
Принадлежит:

Methods of preparing a dentifrice comprising polymer matrix film with menthol therein are disclosed. The methods comprise combining a polymer matrix film that comprises hydrophobic additives and is free of a low solubility flavorant such as menthol with a dentifrice base comprising a low solubility flavorant such as menthol and maintaining the combined polymer matrix film with the dentifrice base comprising low solubility flavorant for an amount of time sufficient for an amount of a low solubility flavorant to transfer from the dentifrice base comprising low solubility flavorant to the polymer matrix film and establish an equilibrium of menthol concentration between the polymer matrix film and the dentifrice base. Products comprising low solubility flavorant-free polymer matrix film in a dentifrice base comprising low solubility flavorant are also disclosed. 1. A method of preparing a dentifrice comprising polymer matrix film with low solubility flavorant therein comprising the steps of:a) forming a polymer matrix film in the substantial absence of low solubility flavorant, wherein said polymer matrix comprises a water soluble polymer and a hydrophobic/lipophilic additive;b) forming a dentifrice base comprising a low solubility flavorant;c) combining the polymer matrix film with the dentifrice base; andd) maintaining the combined polymer matrix film and dentifrice base for an amount of time suitable for an effective amount of low solubility flavorant to transfer from said dentifrice base to said polymer matrix film.2. The method of wherein the low solubility flavorant is selected from the group consisting of: menthol claim 1 , spearmint oil claim 1 , cinnamon oil claim 1 , peppermint oil claim 1 , clove oil claim 1 , bay oil claim 1 , thyme oil claim 1 , cedar leaf oil claim 1 , oil of nutmeg claim 1 , oil of sage claim 1 , and oil of bitter almonds.3. The method of wherein the one or more hydrophobic/lipophilic additives are selected from the group consisting of: ...

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Номер записи: 70
10-10-2013 дата публикации

Oral Compositions

Номер: US20130266524A1
Автор: Gu Ben, Hassan Mahmoud
Принадлежит: Cologate-Palmolive Company

Described herein, are films, compositions containing the films and methods of preparing a dentifrice comprising the films, wherein the films contain a low solubility flavorant. 1. A method of preparing a dentifrice comprising a polymer matrix film with low solubility flavorant contained therein comprising the steps of:a) forming a polymer matrix film comprising a water soluble polymer, a low solubility flavorant, and at least one material chosen from a low solubility polymer additive and a hydrophobic/lipophilic additive;b) providing a dentifrice base; andc) combining the polymer matrix film with the dentifrice base.2. The method of claim 1 , wherein the low solubility flavorant is selected from the group consisting of: menthol claim 1 , spearmint oil claim 1 , cinnamon oil claim 1 , peppermint oil claim 1 , clove oil claim 1 , bay oil claim 1 , thyme oil claim 1 , cedar leaf oil claim 1 , oil of nutmeg claim 1 , oil of sage claim 1 , and oil of bitter almond claim 1 , said water soluble polymer comprises hydroxypropyl methyl cellulose and the low solubility polymer additive is ethyl cellulose.3. (canceled)4. (canceled)5. (canceled)6. The method of claim 1 , wherein the combined water soluble polymer and low solubility polymer additive makes up by weight 40 to 90% of polymer film matrix claim 1 , and the ratio of water soluble polymer to low solubility polymer additive by weight is 10:1 and 2.75:1.7. The method of claim 1 , wherein the amount of low solubility polymer additive in the polymer matrix film is 7% to 33% by weight claim 1 , or 11% to 21% by weight and the amount of water soluble polymer in the polymer matrix film is 56% to 70% by weight or 56% to 66% by weight.8. (canceled)9. The method of claim 1 , wherein the hydrophobic/lipophilic additive is selected from the group consisting of: petrolatum claim 1 , silicone oil claim 1 , beeswax claim 1 , hydrogenated soybean oil claim 1 , sweet almond oil claim 1 , peanut oil claim 1 , avocado oil claim 1 , borage ...

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Номер записи: 71
17-10-2013 дата публикации

Gelatin Encapsulated Oral Care Composition Containing Dental Occlusion Actives, Hydrophobic Viscosity Modifier and Oil Carrier

Номер: US20130269132A1
Автор: Boyd Thomas James, Brown James Richard, Chopra Suman Kumar, Mello Sarita Vera, Ontumi Dennis Kembero, Patel Rahul
Принадлежит: Colgate-Palmolive Company

A oral care composition includes: (a) a guanidine active; (b) a film-forming polymer; (c) a hydrophobic viscosity modifier in an amount sufficient to provide the oral care composition with a particle settling time greater than 20 minutes; and (d) an oil carrier. The guanidine active is preferably L-arginine. The film-forming polymer is preferably GANTREZ. The hydrophobic viscosity modifier is preferably a gelled mineral oil. The oil carrier is preferably a vegetable oil. A method of cleaning teeth includes applying to the teeth the oral care composition such that the oral care composition cleans the teeth. A oral care implement includes: a handle; a head mounted to the handle, the head having an outer surface and a plurality of tooth cleaning elements extending outwardly from the outer surface; and a gelatin capsule containing the oral care composition positioned on the head. 2. (canceled)3. The oral care composition of claim 1 , wherein the guanidine active constitutes 1-10 wt. % of the oral care composition.4. The oral care composition of claim 1 , wherein the guanidine active is L-arginine.5. The oral care composition of claim 1 , wherein the film-forming polymer constitutes 1-5 wt. % of the oral care composition.6. The oral care composition of claim 1 , wherein the film-forming polymer is a copolymer of methyl vinyl ether and maleic anhydride.7. The oral care composition of claim 1 , wherein the hydrophobic viscosity modifier comprises a gelled mineral oil.8. The oral care composition of claim 7 , wherein the gelled mineral oil is a plastigel comprising polyethylene and mineral oil.9. The oral care composition of claim 1 , wherein the oil carrier constitutes 60-80 wt. % of the oral care composition.10. The oral care composition of claim 1 , wherein the oil carrier comprises at least one of a vegetable oil and silicone oil.11. The oral care composition of claim 1 , wherein the oil carrier comprises a C6 to C12 triglyceride.12. The oral care composition of claim 1 ...

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Номер записи: 72
17-10-2013 дата публикации

Gelatin Encapsulated Oral Care Composition Containing Hydrophilic Active, Hydrophobic Structuring Agent and Oil Carrier

Номер: US20130269133A1
Автор: Boyd Thomas James, Brown James Richard, Chopra Suman Kumar, Ontumi Dennis Kembero
Принадлежит: Colgate-Palmolive Company

An encapsulated oral care composition includes: (a) a gelatin capsule; and (b) a oral care composition contained within the capsule, and including: (i) a hydrophilic active; (ii) a hydrophobic structuring agent; and (iii) an oil carrier. The hydrophilic active is preferably cetylpyridinium chloride. The hydrophobic structuring agent is preferably a gelled mineral oil. The oil carrier is preferably a vegetable oil. A method of cleaning teeth includes applying to the teeth the encapsulated oral care composition such that the capsule releases the oral care composition to clean the teeth. A oral care implement includes: a handle; a head mounted to the handle, the head having an outer surface and a plurality of tooth cleaning elements extending outwardly from the outer surface; and the encapsulated oral care composition positioned on the head. 1. An encapsulated oral care composition comprising:(a) a water soluble capsule; and i. a hydrophilic active;', 'ii. a hydrophobic structuring agent; and', 'iii. a hydrophobic carrier., '(b) a oral care composition contained within the capsule, and comprising2. The composition of claim I , wherein the hydrophobic structuring agent comprises a gelled mineral oil.3. The composition of claim 1 , wherein the hydrophilic active comprises a solid active.4. The composition of claim 1 , wherein the hydrophobic structuring agent comprises the gelled mineral oil in an amount of 1-20 wt. % based on a total weight of the oral care composition.5. The composition of claim 1 , wherein the gelled mineral oil is a plastigel comprising polyethylene and mineral oil.6. The composition of claim 1 , wherein the carrier comprises at least one of a vegetable oil and silicone oil claim 1 ,7. The composition of claim 1 , wherein the carrier comprises a C6 to C12 triglyceride.8. The composition of claim 1 , wherein the carrier constitutes 60-80 wt. % of the oral care composition.9. The composition of claim 1 , wherein the hydrophilic active is ...

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Номер записи: 73
17-10-2013 дата публикации

Fluid Compositions Comprising a Structuring Agent

Номер: US20130272970A1
Автор: Nesta Jason, Pimenta Paloma
Принадлежит: Colgate-Palmolive Company

Described herein are oral fluid compositions comprising one or more structuring agents, and methods of making and using the same. 2. The composition of claim 1 , wherein the total concentration of said one or more structuring agents is less than about 5% claim 1 , by weight claim 1 , of the composition.3. The composition of claim 2 , wherein at least one of said one or more structuring agents is a gum-type colloidal polymer claim 2 , a cellulosic polymer and an acrylate polymer.45-. (canceled)6. The composition of claim 3 , wherein structuring agents further comprises a clay or fine particulate.7. The composition of claim 3 , wherein at least one of said one or more structuring agents is a gum-type colloidal polymer selected from: agar claim 3 , agarose claim 3 , albumin claim 3 , algae colloid claim 3 , alginates claim 3 , alginic acid and salts thereof claim 3 , amber claim 3 , ammoniac claim 3 , amylopectins claim 3 , arabinans claim 3 , arabinogalactan claim 3 , arabinoxylans claim 3 , asafetida claim 3 , bdellium claim 3 , carageenans claim 3 , casein claim 3 , chicle claim 3 , collagen claim 3 , copal claim 3 , curdlan claim 3 , dermatin sulfate claim 3 , dextrans claim 3 , cross-linked dextrans claim 3 , dextrin claim 3 , emulsan claim 3 , gelatin claim 3 , fenugreek claim 3 , frankincense claim 3 , furcellarans claim 3 , galactoglucomannas claim 3 , galactomannans claim 3 , gamboge claim 3 , gellan claim 3 , gellan gum claim 3 , glucomannans claim 3 , glycogens claim 3 , guar claim 3 , guar gum claim 3 , hydroxypropylated guar gums claim 3 , carboxymethyl guar gum claim 3 , carboxymethyl(hydroxypropyl) guar gum claim 3 , hydroxyethyl guar gum claim 3 , gum arabic claim 3 , gum elastic claim 3 , gum ghatti claim 3 , gum karaya claim 3 , gum tragancanth (tragacanthin) claim 3 , heparin claim 3 , hyaluronic acid claim 3 , India rubber claim 3 , inulin claim 3 , karaya gum claim 3 , keratin sulfate claim 3 , konjac flour claim 3 , konjac mannan claim 3 , ...

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Номер записи: 74
17-10-2013 дата публикации

Dentifrice Containing Functional Film Flakes

Номер: US20130272973A1
Автор: Boyd Thomas J., Carale M. Teresa R., Xu Guofeng
Принадлежит:

A dentifrice composition comprising an orally acceptable vehicle having distributed therein a water hydratable film flakes having a matrix comprised of a water soluble hydroxy alkyl cellulose polymer and a starch, and flaying entrained therein a constituent selected from therapeutic cosmetic and decorative materials. 1. A dentifrice composition comprising an orally acceptable vehicle and film flakes ,the flakes being distributed within the vehicle, comprising from about 0.05 to about 1.0% by total weight of the composition, and being comprised of a film matrix and at least one constituent,wherein the matrix is comprised of a water soluble material and the at least one constituent is selected from the group consisting of flavorants, therapeutic agents, cosmetic agents, and combinations thereof.2. A dentifrice according to claim 1 , wherein the at least one constituent comprises a flavorant.3. A dentifrice according to claim 1 , wherein the flavorant comprises from about 15 to about 25 percent by weight of the film flakes.4. A dentifrice according to claim 1 , wherein the flavorant comprises an amount to release a burst of flavor during toothbrushing.5. A dentifrice according to claim 1 , wherein the matrix comprises hydroxyalkyl cellulose.6. A dentifrice according to claim 5 , wherein the hydratable matrix comprises from about 10 to about 60% hydroxyalkylmethyl cellulose and wherein the hydroxyalkyl cellulose comprises a member selected from the group consisting of hydroxypropyl methyl cellulose claim 5 , hydroxyethylpropyl cellulose claim 5 , hydroxybutyl methyl cellulose claim 5 , hydroxypropyl methyl cellulose claim 5 , and combinations thereof.7. A dentifrice according to claim 6 , wherein the film matrix further comprises cornstarch.8. A dentifrice according to claim 1 , wherein the dentifrice vehicle is substantially clear and the film flakes are shaped flakes end comprise a colorant.9. A dentifrice according to claim 8 , wherein the vehicle comprises a ...

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Номер записи: 75
17-10-2013 дата публикации

Appetizing and Dentally Efficacious Animal Chews

Номер: US20130273125A1
Автор: BARNVOS Donald R., Berry John F., Cope Melinda S., Davor Juravic, Donatucci Mark, Ortiz Oscar
Принадлежит: Del Monte Corporation

Described herein are chewable articles intended to be provided to animals for purposes including dental cleaning, breath freshening, nutrition, administration to the animal of beneficial agents, satisfaction of the animal's urge to chew, and general enjoyment by the animal. The chews are made to be appetizing to the animal, to satisfy an urge to chew, to effect abrasive cleaning of the animal's teeth, to deliver one or more active agents to the oral cavity of the animal, or a combination of these. The chews have a resilient, chewable texture and are shaped to facilitate dental cleaning, to facilitate oral grasping by the animal, to appeal to human owners of the animal, to enhance the human-animal bond, or a combination of these. Also disclosed are apparatus and methods for making such chewable articles and for formulating and using them to effect dental health in animals. 1. An animal chew having a consumable portion , the consumable portion comprising a chewable matrix and having dimensions selected to fit within the oral cavity of the wherein the chewable matrix comprises:i) about 9-17 wt % protein,ii) about 40-50 wt % starch,iii) water and, optionally, a humectant, amounts sufficient to confer rub plasticity to the chewable matrix, andiv) a temporally efficacious amount of an orally active ingredient.2. (canceled)3. The chew of claim 1 , wherein at least about 50 wt % of the starch in the chewable matrix is gelatinized.4. The chew of claim 3 , wherein about at least about 80 wt % of the starch in the chewable matrix is gelatinized.57-. (canceled)8. The chew of claim wherein the chewable matrix comprises a humectant.9. The chew of claim 8 , wherein the humectant is selected from the group consisting of glycerol claim 8 , propylene glycol claim 8 , and a combination of these claim 8 , and is present in an amount that is about 4-12 wt % of the chewable matrix.10. (canceled)11. The chew of claim 1 , wherein the chewable matrix further comprises one or more additional ...

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Номер записи: 76
17-10-2013 дата публикации

HYDROGEL COMPOSITIONS WITH AN ERODIBLE BACKING MEMBER

Номер: US20130273127A1
Автор: Bairamov Danir F., Cleary Gary W., Faasse Adrian, Feldstein Mikhail M., Mudumba Sri, Singh Parminder
Принадлежит:

A composition is provided, wherein the composition comprises a water-swellable, water-insoluble polymer, a blend of a hydrophilic polymer with a complementary oligomer capable of hydrogen or electrostatic bonding to the hydrophilic polymer. The composition also includes a backing member. Active ingredients, such as a whitening agent, may be included. The composition finds utility as an oral dressing, for example, a tooth whitening composition that is applied to the teeth in need of whitening. The composition can be designed to be removed when the degree of whitening has been achieved or left in place and allowed to erode entirely. In certain embodiments, the composition is translucent. Methods for preparing and using the compositions are also disclosed. 1. A composition , comprising: (i) a water-swellable, water-insoluble acrylate polymer which is a copolymer of methacrylic acid and methyl methacrylate and is insoluble in aqueous fluid having a pH of 5.5 or below;', '(ii) a blend of a hydrophilic polymer with a complementary oligomer capable of hydrogen or electrostatic bonding to the hydrophilic polymer; and', '(iii) an active agent; and, '(a) a hydrogel comprising(b) a backing member comprising a material selected from acrylate polymers, starches, alginic acid, alginates, polyamino acids, and combinations thereof, wherein said backing member erodes in a moist environment at a slower rate than the hydrogel.2. A composition , comprising: (i) a water-swellable, water-insoluble cellulose ester polymer which renders the hydrogel tacky prior to application to a moist surface, but nontacky upon absorption of water;', '(ii) a blend of a hydrophilic polymer with a complementary oligomer capable of hydrogen or electrostatic bonding to the hydrophilic polymer; and', '(iii) an active agent; and, '(a) a hydrogel comprising(b) a backing member that erodes in a moist environment at a slower rate than the hydrogel.3. A composition , comprising: (i) a water-swellable alginic acid ...

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Номер записи: 77
17-10-2013 дата публикации

Films and Compositions Comprising the Same

Номер: US20130273128A1
Автор: Boyd Thomas, Leigh Leonora, Martinetti Melissa A., Nesta Jason
Принадлежит: Colgate-Palmolive Company

Described herein are water-stable films for use in aqueous compositions comprising one or more cellulosic polymers present in an amount from about 10 to about 50% of the film's dry weight, polyvinyl acetate present in an amount from about 8 to about 25% of the film's dry weight and metal particles, compositions for oral cavity comprising the films, and methods of making and using the same 1. A water-stable film , comprising:one or more cellulosic polymers present in an amount from about 10 to about 50% of the film's dry weight,polyvinyl acetate present in an amount from about 8 to about 25% of the film's dry weight; andparticles selected from silicon oxide, molybdenum oxide, aluminum oxide, titanium oxide, zirconium oxide and zinc oxide, wherein the particles are present at a concentration of greater than about 30% to about 60% of the film's dry weight.2. The film of claim 1 , wherein the polyvinyl acetate is present at a concentration of from about 10 to about 20% of the film's dry weight.3. (canceled)4. The film of claim 2 , the one or more cellulosic polymers are present at a concentration of from about 15 to about 30% claim 2 , of the film's dry weight.5. The film of claim 4 , wherein the one or more cellulosic polymers are present at a concentration of from about 18 to about 22% claim 4 , of the film's dry weight.6. (canceled)7. The film of claim 5 , wherein the particles are present at a concentration of from about 45 to about 55% of the film's dry weight.8. The film of claim 7 , wherein the particles are zinc oxide particles.9. The film of claim 8 , wherein at least one of the one or more cellulosic polymers is hydroxypropyl methyl cellulose.10. An aqueous oral care composition comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'the film of ; and'}an orally acceptable aqueous carrier;wherein the film is present at a concentration of from about 0.1 to about 2%, by weight of the composition.11. The composition of claim 10 , wherein the composition has ...

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Номер записи: 78
24-10-2013 дата публикации

ANTIMICROBIAL MICROEMULSION MOUTHWASH COMPOSITION

Номер: US20130280180A1
Автор: Rout Deeleep Kumar, Saji Maya Treesa, Sinha Ritesh Kumar
Принадлежит:

The invention relates to a transparent/translucent liquid antimicrobial mouthwash composition that is substantially free of low molecular weight alcohol. It is a problem to include antimicrobial actives of natural origin (essential oils) which are generally substantially water insoluble materials in an aqueous composition that is transparent or translucent. One way of including such oils in water while ensuring transparency is to formulate them in a microemulsion composition. However microemulsion compositions generally require high amounts of surfactants and solvents especially low molecular weight alcohol. It is thus a challenge to formulate a mouthwash composition that is on the one hand effective in killing microbes while on the other hand has a transparent/translucent appearance while being substantially free of low molecular weight alcohol. The present inventors have solved this problem and have come up with a microemulsion mouthwash composition which meets all of the above objectives while being especially effective in killing , a bacteria responsible for diseases in oral cavity. 1. A transparent/translucent liquid antimicrobial mouthwash composition in micro emulsion format substantially free of C1 to C3 alcohol comprising:(i) 0.05% to 10% of an antimicrobial active selected from the class comprising, terpenes, essential oils, cationic oils, C6 to C10 fatty acids, fatty acid methyl esters, or organic per-acidshaving a solubility in water of less than 2000 ppm at 25° C.;(ii) 0.05 to 10% of an anionic or cationic surfactant;(iii) 0.01 to 50% of an electrolyte; and(iv) 50 to 99.9% water.2. A composition as claimed in wherein said surfactant is an alkali or alkaline earth metal salt of alkyl sulphonic acid or fatty acid; or alkyl ether sulphate.3. A composition as claimed in or wherein said antimicrobial active is terpineol claim 1 , thymol claim 1 , eugenol claim 1 , borneol claim 1 , or limonene.4. A composition as claimed in any one of the preceding claims ...

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Номер записи: 79
24-10-2013 дата публикации

Fluid Oral Care Compositions

Номер: US20130280181A1
Автор: Martinetti Melissa A., Nesta Jason, Pimenta Paloma, Szewczyk Gregory
Принадлежит: Colgate-Palmolive Company

Described herein are compositions comprising gums which are capable of suspending particles, and methods of making and using the same. 2. The composition of claim 1 , wherein the total gum concentration is from about 0.05 to about 0.12% by weight.3. The composition of claim 1 , wherein the cation is selected from: a sodium salt; a potassium salt; a magnesium salt; a calcium salt; and a combination of two or more thereof.4. The composition of claim 1 , wherein the cation is a sodium salt.5. The composition of claim 4 , wherein the sodium salt concentration is present at a concentration of at least 0.5% by weight.6. The composition of claim 1 , wherein the composition has a G′/G″ ratio of from about 1 to about 10.7. The composition of claim 1 , wherein the composition has a G′/G″ ratio of from about 5 to about 6.8. The composition of claim 1 , wherein the composition has a G′/G″ ratio of about 5.5.9. The composition of claim 1 , further comprising a humectant.10. The composition of claim 9 , wherein the humectant is selected from: glycerin; sorbitol; ethanol; propylene glycol; and a combination of two or more thereof.11. The composition of claim 1 , wherein the orally acceptable aqueous carrier has a free water concentration of greater than about 50% claim 1 , by weight.12. The composition of claim 9 , wherein the water to humectant ratio is from about 4:1 to about 2:3.13. The composition of claim 1 , wherein the suspended material is a solid or semi-solid particle claim 1 , or a film comprising one or more polymers.14. The composition of claim 1 , wherein the suspended material is a solid or semi-solid particle.15. The composition of claim 13 , wherein the solid or semi-solid particle is zinc oxide.16. The composition of claim 2 , wherein the cation is selected from: a sodium salt; a potassium salt; a magnesium salt; a calcium salt; and a combination of two or more thereof claim 2 , wherein the composition has a G′/G″ ratio of from about 1 to about 10 and the orally ...

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Номер записи: 80
24-10-2013 дата публикации

ANTICARIOGENIC DENTIFRICE COMPOSITION COMPRISING PROPOLIS AS ANTICARIOGENIC ACTIVE INGREDIENT

Номер: US20130280183A1
Автор: Montenegro Rizzardinni Gloria Del Carmen, Salazar Navarrete Luis Antonio
Принадлежит:

The invention is referred to a new dentifrice composition with anticariogenic properties, which has as active anticariogenic ingredients a combination of propolis, methylparaben and propylparaben. From these 3 components, propolis is the major component, which is reinforced in its activity for a smaller amount of methylparaben and propylparaben obtaining a composition with a high anticariogenic composition without side effects. These active ingredients are present in the following percentages in relation to the total weight of the dentifrice composition: 2. The anticariogenic dentifrice composition according to the claim 1 , wherein the fluorinated compound is found in a percentage between 0.2 to 2% with respect to the total weight of the dentifrice composition.3. The anticariogenic dentifrice composition according to the claim 2 , wherein having fluorinated compound at least one of the following compounds: sodium fluoride claim 2 , sodium monofluorophosphate claim 2 , nicomethanol hydrofluoride (fluorinol) claim 2 , stannous fluoride claim 2 , amine fluoride or potassium fluoride and their mixtures.4. The anticariogenic dentifrice composition according to the claim 1 , wherein having between 20 to 50% of abrasives claim 1 , between 20 to 50% of moisturizing claim 1 , between 0.5 and 3% of foaming agents claim 1 , between 0.1 to 4% of thickeners claim 1 , between 0.05 to 5% of sweeteners claim 1 , between 0.25 to 1.5% of flavorants claim 1 , between 0 to 1.5% of whiteners claim 1 , and between 30 to 60% of demineralized water. The invention is focused on a dentifrice composition, specifically, in toothpaste for massive use, which has a natural active ingredient, specifically propolis. The use of this anticariogenic dentifrice composition decreases the bacterial load of , from the mutants group, with a 70% of effectiveness without side effects. Therefore, this dentifrice may be used for long time (>1 month) and could be purchased over the counter without doctor's ...

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Номер записи: 81
24-10-2013 дата публикации

Oral Compositions and Method for Producing Thereof

Номер: US20130280184A1
Автор: Gu Ben, Hassan Mahmoud
Принадлежит: Colgate-Palmolive Company

Methods of preparing a dentifrice comprising polymer matrix film with a low solubility flavorant therein are disclosed. The methods comprise combining a polymer matrix film that are free of a low solubility flavorant with a dentifrice base comprising a low solubility flavorant and maintaining the combined polymer matrix film with the dentifrice base comprising low solubility flavorant for an amount of time sufficient for an amount of a low solubility flavorant to transfer from the dentifrice base comprising low solubility flavorant to the polymer matrix film Products comprising low solubility flavorant-free polymer matrix film in a dentifrice base comprising low solubility flavorant are also disclosed. 1. A method of preparing a dentifrice comprising polymer matrix film with low solubility flavorant therein comprising the steps of:a) forming a polymer matrix film in the substantial absence of low solubility flavorant, wherein said polymer matrix comprises a water soluble polymer;b) forming a dentifrice base comprising a low solubility flavorant;c) combining the polymer matrix film with the dentifrice base; andd) maintaining the combined polymer matrix film and dentifrice base for an amount of time suitable for an effective amount of low solubility flavorant to transfer from said dentifrice base to said polymer matrix film.2. The method of wherein the low solubility flavorant is selected from the group consisting of: menthol claim 1 , spearmint oil claim 1 , cinnamon oil claim 1 , peppermint oil claim 1 , clove oil claim 1 , bay oil claim 1 , thyme oil claim 1 , cedar leaf oil claim 1 , oil of nutmeg claim 1 , oil of sage claim 1 , and oil of bitter almonds.3. The method of wherein the polymer matrix film comprises cellulose polymers.4. The method of wherein said cellulose polymers comprise hydroxypropyl methyl cellulose.5. The method of claim lany of wherein the polymer matrix film comprises zinc oxide.6. The method of wherein the polymer matrix film further ...

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Номер записи: 82
24-10-2013 дата публикации

Compounds and Compositions

Номер: US20130280185A1
Автор: ANSARI Shamim, Gronlund Jennifer, Subramanyam Ravi, Xu Guofeng
Принадлежит: Colgate-Palmolive Company

Described herein are compounds of Formula (I): or a salt thereof; wherein: R1 and R5 are independently selected from H, OH and alkoxy; R-Rand R-Rare independently selected from H, OH, F, Cl, Br, and I; Rand Rare independently selected from H, alkyl, alkenyl, alkynyl, and aryl; with the proviso that: at least one of R and Ris OH or alkoxy; and at least one of CR-Rand R-Ris F, Cl, Br or I; compositions comprising said compounds; and methods of making and using the same. 2. The compound of claim 1 , wherein:{'sub': 1', '5, 'Rand Rare independently selected from OH or alkoxy; and'}{'sub': 2', '6, 'Rand Rare independently selected from H, F, Cl, Br and I.'}3. The compound of claim 1 , wherein Rand Rare OH.4. The compound of claim 1 , wherein Rand Rare OH.7. A composition comprising the compound of ; and a carrier.8. The composition of claim 7 , wherein the carrier is an orally acceptable carrier.9. The composition of claim 7 , wherein the compound of Formula (I) is present at a concentration of from about 0 claim 7 ,01 to about 1% claim 7 , by weight.10. The composition of claim 7 , wherein the compound of Formula (I) is present at a concentration of from about 0.1 to about 0.75% claim 7 , by weight.11. The composition of claim 7 , wherein the compound of Formula (I) is present at a concentration of about 0.5% claim 7 , weight.12. The composition of claim 7 , further comprising one or more components selected from a fluoride ion source; a tartar control agent; a buffering agent; an abrasive; and a combination of two or more thereof.13. The composition of claim 12 , wherein at least one of the one or more components is a fluoride ion source selected from: stannous fluoride claim 12 , sodium fluoride claim 12 , potassium fluoride claim 12 , sodium monofluorophosphate claim 12 , sodium fluorosilicate claim 12 , ammonium fluorosilicate claim 12 , amine fluoride claim 12 , ammonium fluoride claim 12 , and a combination of two or more thereof.14. A method of treating or ...

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Номер записи: 83
24-10-2013 дата публикации

Polymer Systems

Номер: US20130280186A1
Автор: "DAmbrogio Robert", Dillon Rensl, Masters James G., Viscio David B.
Принадлежит: Colgate-Palmolive Company

Disclosed herein are polymer systems and compositions comprising polymer systems, and methods of preparing and using the same. 2. The polymer system of claim 1 , wherein at least one of said one or more anionic mucoadhesive polysaccharide polymers is carboxymethyl cellulose.3. The polymer system of claim 1 , wherein at least one of said one or more anionic mucoadhesive polysaccharide polymers is xanthan gum.4. The polymer system of claim 1 , wherein said acrylate polymer is carbomer and said chitosan derivative is selected from: dicarboxylic acid chitosan; chitin-glucan; and carboxymethyl chitosan.5. (canceled)6. The polymer system of claim 4 , wherein said chitosan derivative is carboxymethyl chitosan.7. (canceled)8. A toothpaste composition comprising: one or more anionic mucoadhesive polysaccharide polymers in a total amount of from about 0.8 to about 2.4%, by weight of the composition;', 'an acrylate polymer in the amount of from about 0.4 to 1.2%, by weight of the composition;', 'a chitosan derivative in the amount of from about 1 to 10%, by weight of the composition; and, 'a polymer system comprisingan orally acceptable carrier.9. The composition of claim 8 , wherein the polymer system comprises:one or more anionic mucoadhesive polysaccharide polymers in a total amount of from about 1.2 to about 2%, by weight of the composition;an acrylate polymer in the amount of from about 0.6 to 1%, by weight of the composition; anda chitosan derivative in the amount of from about 3 to 7%, by weight of the composition.10. (canceled)11. The composition of claim 8 , wherein at least one of said one or more anionic mucoadhesive polysaccharide polymers is carboxymethyl cellulose and said one or more anionic mucoadhesive polysaccharide polymers is xanthan gum.12. (canceled)13. The composition of claim 11 , wherein said chitosan derivative is carboxymethyl chitosan.14. (canceled)15. The composition of claim 8 , further comprising trimethylglycine.16. The composition of claim 8 , ...

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Номер записи: 84
31-10-2013 дата публикации

Metal Salt Compositions

Номер: US20130287709A1
Автор: Fisher Steven Wade, Jaracz Stanislav, Maloney Venda Porter, Morgan Andre Michelle, Patel Vyoma, Prencipe Michael
Принадлежит: Colgate-Palmolive Company

Described herein are compositions comprising combinations of metal salts, and methods of preparing and using the same. 2. The composition of claim 1 , wherein the first metal salt and the second metal salt are salts of the same metal.3. The composition of claim 1 , wherein the second metal salt is present in an amount effective to provide a synergistic increase in delivery of the metal ion of the first metal salt.4. The composition of claim 1 , wherein the first metal salt is selected from: zinc citrate trihydrate claim 1 , zinc chloride claim 1 , zinc lactate claim 1 , zinc nitrate claim 1 , zinc acetate claim 1 , zinc gluconate claim 1 , zinc glycinate and zinc sulfate.5. The composition of claim 1 , wherein the second metal salt is selected from: zinc oxide claim 1 , zinc phosphate claim 1 , zinc pyrophosphate claim 1 , zinc silicate claim 1 , zinc oleate claim 1 , zinc hydroxide claim 1 , zinc peroxide claim 1 , and zinc sulfide.6. The composition of claim 1 , comprising:from about 0.1 to about 5%, by weight, of said first metal salt; andfrom about 0.05 to about 2%, by weight, of said second metal salt.7. The composition of claim 1 , comprising:from about 0.5 to about 4%, by weight, of said first metal salt; andfrom about 0.1 to about 1.5%, by weight, of said second metal salt.8. The composition of claim 1 , comprising:from about 1 to about 3%, by weight, of said first metal salt; andfrom about 0.2 to about 0.75%, by weight, of said second metal salt.9. The composition of claim 1 , comprising:about 2%, by weight, of said first metal salt; andabout 0.25%, by weight, of said second metal salt.10. The composition of claim 1 , comprising:about 2%, by weight, of said first metal salt; andabout 0.5%, by weight, of said second metal salt.11. The composition of claim 1 , further comprising one or more components selected from a fluoride ion source; a tartar control agent; a buffering agent; an antibacterial agent; an abrasive; and a combination of two or more thereof.12 ...

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Номер записи: 85
31-10-2013 дата публикации

Oral Care Compositions

Номер: US20130287710A1
Автор: Chopra Suman, Maloney Venda Porter, Mandadi Prakasarao, Ontumi Dennis
Принадлежит: Colgate-Palmolive Company

Oral care compositions comprising a crosslinked polyvinylpyrrolidone complexed with hydrogen peroxide, together with an ethylene oxide-propylene oxide block copolymer. Some embodiments further comprise a calcium abrasive, e.g. calcium pyrophosphate or calcium carbonate, and some may have less than 3% water. 1. A dentifrice composition comprising(i) a whitening complex comprising cross linked polyvinylpyrrolidone complexed with hydrogen peroxide, wherein the whitening complex contains about 10-30% hydrogen peroxide, by weight, and about 5-15% total nitrogen by weight,(ii) an ethylene oxide, propylene oxide block co-polymer of average molecular weight greater than 5000 Da, being substantially free of an ethylene oxide, propylene oxide block co-polymer of average molecular weight less than 5000 Da.2. The composition of wherein the ethylene oxide claim 1 , propylene oxide block co-polymer comprises (ethylene oxide)-(propylene oxide)wherein x is an integer of 80-150 and y is an integer 30-80.3. The composition of wherein the total amount of hydrogen peroxide by weight of the composition is 0.5-3%.4. The composition of additionally comprising polyethylene glycol of average molecular weight 400 to 800 Da.5. The composition of claim which contains less than 3% water.6. The composition of which is a toothpaste comprising a calcium abrasive selected from a calcium phosphate salt and calcium carbonate.7. The composition of wherein the calcium abrasive comprises calcium pyrophosphate.9. The composition of which is a gel non-abrasive dentifrice.10. The composition of comprising additional linear and/or crosslinked polyvinylpyrrolidone.12. The composition of claim 11 , wherein the additional linear and/or crosslinked polyvinylpyrrolidone is present at a concentration of about 9% claim 11 , by weight.13. The composition of claim 11 , further comprising a calcium abrasive selected from a calcium phosphate salt and calcium carbonate.14. The composition of claim 13 , wherein the ...

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Номер записи: 86
31-10-2013 дата публикации

Oral Compositions and Method for Producing Thereof

Номер: US20130287711A1
Автор: Gu Ben, Hassan Mahmoud
Принадлежит: Colgate-Palmolive Company

Methods of preparing a dentifrice comprising polymer matrix film with a low solubility flavorant therein are disclosed. The methods comprise combining a polymer matrix film that are free of a low solubility flavorant with a dentifrice base comprising a low solubility flavorant and maintaining the combined polymer matrix film with the dentifrice base comprising low solubility flavorant for an amount of time sufficient for an amount of a low solubility flavorant to transfer from the dentifrice base comprising low solubility flavorant to the polymer matrix film Products comprising low solubility flavorant-free polymer matrix film in a dentifrice base comprising low solubility flavorant are also disclosed. 1. A method of preparing a dentifrice comprising polymer matrix film with low solubility flavorant therein comprising the steps of:a) forming a polymer matrix film in the substantial absence of low solubility flavorant; wherein said polymer matrix comprises a water soluble polymer and a low solubility polymer additive;b) forming a dentifrice base comprising a low solubility flavorant;c) combining the polymer matrix film with the dentifrice base; andd) maintaining the combined polymer matrix film and dentifrice base for an amount of time suitable for an effective amount of low solubility flavorant to transfer from said dentifrice base to said polymer matrix film.2. The method of wherein the low solubility flavorant is selected from the group consisting of: menthol claim 1 , spearmint oil claim 1 , cinnamon oil claim 1 , peppermint oil claim 1 , clove oil claim 1 , bay oil claim 1 , thyme oil claim 1 , cedar leaf oil claim 1 , oil of nutmeg claim 1 , oil of sage claim 1 , and oil of bitter almonds claim 1 , said water soluble polymers comprise hydroxypropyl methyl cellulose and the low solubility polymer additive is ethyl cellulose.35-. (canceled)6. The method of wherein the combined water soluble polymer and low solubility polymer additive makes up by weight between 40 ...

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Номер записи: 87
31-10-2013 дата публикации

FLUORIDE VARNISH

Номер: US20130288194A1
Автор: Herron Christopher J., Krone Richard A., Stookey George K., Swanson Jerome E.
Принадлежит: Therametric Technologies, Inc.

A tooth varnish that is free from pinus extracts, free of substantial undesired coloring agents, with a reduced viscosity, delivered in a user-friendly, flow-through, unit dose applicator and having improved fluoride release, uptake, and remineralization properties. 1. A tooth coating composition comprising:shellac;fluoride; anda carboxylic acid.2. The composition of claim 1 , further comprising alcohol.3. The composition of claim 2 , wherein the content of the alcohol is in a range of 38%-90% by weight.4. The composition of claim 1 , wherein the content of the shellac is in a range of 5-40% by weight.5. The composition of claim 4 , wherein the content of the shellac is in a range of 25-35% by weight.6. The composition of claim 1 , wherein the content of the carboxylic acid is less than 5% by weight and the shellac is an insect based shellac.7. The composition of claim 6 , wherein the content of the carboxylic acid is in the range of 0.5%-3% by weight.8. The composition of claim 1 , wherein the acid is citric acid.9. A tooth coating composition comprising:milled fluoride, at least 80% of the milled fluoride particles having a greatest width dimension of less than 15 microns.10. The tooth coating composition of claim 9 , further including alcohol claim 9 , the alcohol comprising at least 45% by weight of the tooth coating composition.11. The tooth coating composition of claim 10 , further including a base ingredient claim 10 , the base ingredient comprising 20%-40% of the tooth coating composition by weight.12. The tooth coating composition of claim 11 , comprising 25%-35% by weight of the base.13. The tooth coating composition of claim 11 , wherein the base ingredient is a shellac.14. The tooth coating composition of claim 13 , wherein the base ingredient is insect-derived shellac.15. The tooth coating composition of claim 13 , wherein the shellac is a non-water soluble dewaxed claim 13 , bleached shellac.16. The tooth coating composition of claim 9 , further ...

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Номер записи: 88
14-11-2013 дата публикации

Compositions and Formulations for the Treatment of Halitosis

Номер: US20130302387A1
Автор: PEDERSEN Ejvind Jersie
Принадлежит:

An orally disintegrating composition comprising a chelate comprising a metal ion and a biologically acceptable amino acid and having the general formula 2. An orally disintegrating composition according to claim 1 , wherein said chelate is controllably releasable into the oral cavity of a subject.3. An orally disintegrating composition comprising according to claim 1 , wherein the composition is based on one or more polyols claim 1 , such as in the form of the commercially available composition Advantol™ 300.4. An orally disintegrating composition according to claim 1 , wherein the composition is based on one or more polyols having average particle sizes of 90-120 μm.5. An orally disintegrating composition according to claim 3 , wherein the total content of polyols in the composition is between 70 and 85 wt %.6. An orally disintegrating composition according to claim 3 , wherein the polyols are sorbitol claim 3 , mannitol claim 3 , xylitol claim 3 , erythritol claim 3 , maltitol claim 3 , lactitol claim 3 , isomalt and/or mixtures thereof.7. An orally disintegrating composition according to claim 3 , wherein the amounts of polyols are: 70-99.5 wt % mannitol claim 3 , 0.5-30 wt % sorbitol claim 3 , 0-5 wt % xylitol claim 3 , 0-5 wt % erythrol claim 3 , 0-30 wt % maltitol claim 3 , 0-5 wt % lactitol claim 3 , 0.5-20 wt % isomalt of the total amount of polyols and wherein any resulting orally disintegrating composition can comprise all possible combinations of any of said individual amounts.8. An orally disintegrating composition according to comprising Zn in an amount of 0.05 to 4.0 wt %9. An orally disintegrating composition according to claim 1 , wherein all constituents of said composition are completely dissolved in the oral cavity within 180 seconds upon exposure to the saliva claim 1 , preferably within 60 seconds upon exposure to the saliva.10. An orally disintegrating composition according to claim 1 , wherein the orally disintegrating composition comprises ...

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Номер записи: 89
14-11-2013 дата публикации

ORAL CARE COMPOSITIONS COMPRISING PEARLESCENT PIGMENTS

Номер: US20130302393A1
Автор: Joiner Andrew, Parker Andrew Philip, Philpotts Carole Jane
Принадлежит:

The invention provides an oral care composition suitable for delivering a temporary whitening effect to the surface of teeth, the composition comprising: a continuous phase comprising water or polyhydric alcohol or a mixture thereof; a tooth surface whitening agent which is dispersed in the continuous phase, and a deposition aid for the tooth surface whitening agent; characterised in that the tooth surface whitening agent is a pearlescent pigment in an amount of at least 0.1% by weight based on the total weight of the composition, the pearlescent pigment being formed by coating one or more metal oxide layers onto particles of an inorganic substrate. 2. An oral care composition according to claim 1 , in which the pearlescent pigment is selected from natural or synthetic mica flakes coated with TiOand/or FeO.3. An oral care composition according to claim 2 , in which the pearlescent pigment is selected from natural or synthetic mica flakes coated with TiO claim 2 , the pigment having a silver-white colour and the pigment having a mean particle diameter which is less than 25 microns.4. (canceled)5. (canceled)6. An oral care composition according to claim 5 , in which the deposition aid is sodium alginate.7. An oral care composition according to claim 1 , which is in the form of a dentifrice or a mouthwash. The present invention is concerned with oral care compositions. More particularly, the present invention is concerned with oral care compositions containing pearlescent pigments.The colour of the teeth is influenced by a combination of their intrinsic colour and the presence of any extrinsic stains that may form on the tooth surface. Extrinsic colour is linked with the adsorption of materials into the acquired pellicle on the surface of enamel, which ultimately cause staining. Factors that influence extrinsic stain formation include poor tooth brushing technique, smoking, dietary intake of coloured foods (e.g. red wine), subject age and the use of certain cationic ...

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Номер записи: 90
14-11-2013 дата публикации

Intraocular Lens Cell Migration Inhibition System

Номер: US20130304205A1
Автор: Kevin H. Cuevas
Принадлежит: InSight Innovations LLC

Generally, an intraocular implant and methods for treating an ocular condition. In particular, an intraocular implant which implanted between an intraocular lens and the surface of the posterior capsule of the eye inhibits migration of residual lens epithelial cells after cataract surgery by providing structural barriers to reduce posterior capsule opacification of the eye.

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Номер записи: 91
21-11-2013 дата публикации

FOOD PRODUCT TO PREVENT TOOTH DECAY

Номер: US20130309180A1
Автор: Brisley Mark William
Принадлежит:

An anti cavity bioconsumable liquid which may be provided in the liquid form or frozen form is disclosed herein. The liquid may include up to about 5 wt. % xylitol for the purposes of mitigating tooth decay when the bioconsumable liquid is ingested or consumed by a person. Moreover, the bioconsumable liquid may include up to about 5 wt. % of dextrose but never more than the wt. % of xylitol for the purposes of sweetening the bioconsumable liquid to retain an acceptable flavor profile. An infant, child or adult may consume the bioconsumable liquid during which the xylitol acts to mitigate tooth decay. The bioconsumable liquid may also be frozen in an ice pop configuration and consumed by a child or an adult. The ice pop retains an acceptable flavor profile and also mitigates tooth decay. 1. An anti-cavity bioconsumable beverage to prevent plaque formation and tooth decay which retains an acceptable flavor profile , the product comprising liquid , up to about 5 wt. % xylitol and up to 5 wt. % dextrose of the liquid wherein the wt. % of dextrose is less than or about equal to the wt. % of the xylitol.2. The beverage as claimed in claim 1 , wherein the liquid is selected from the group consisting of water claim 1 , milk claim 1 , baby formula and vitamin beverage.3. The beverage as claimed in claim 1 , wherein the product is about 93.45175 wt. % water claim 1 , about 0.002 wt. % B Vitamin Blend claim 1 , about 3.12 wt. % xylitol claim 1 , about 0.25 wt. % Natural Apple flavor claim 1 , about 0.00625 wt. % citric acid claim 1 , about 0.01 wt. % stevia claim 1 , about 3.00 wt. % dextrose claim 1 , and about 0.10 wt. % gum.4. The beverage as claimed in which further includes a coloring additive of about 0.06 wt. % shade amber.5. The beverage as claimed in claim 1 , wherein the product is about 93.43175 wt. % water claim 1 , about 0.002 wt. % B Vitamin Blend claim 1 , about 3.12 wt. % xylitol claim 1 , about 0.10 wt. % Natural Blueberry flavor claim 1 , about 0.00625 wt. % ...

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Номер записи: 92
28-11-2013 дата публикации

Oral Care Compositions

Номер: US20130315845A1
Автор: KHAN Najma, Kohrs Karsten, Pilch Shira, Pimenta Paloma, Sullivan Richard Joseph, Vogt Robert
Принадлежит: Colgate-Palmolive Company

Described herein are oral care compositions comprising a surfactant system; a structuring agent, and a lipophilic agent; and methods of making and using the same. 1. An oral care composition comprising: an anionic surfactant;', 'a zwitterionic surfactant; and', 'a nonionic surfactant;, 'a surfactant system comprisinga structuring agent;a lipophilic agent; andgreater than 20%, by weight, free water.2. The composition of claim 1 , wherein the composition is toothpaste.3. The composition of claim 1 , wherein the structuring agent is a non-cellulose gum-type colloidal polymer.4. The composition of wherein the lipophilic agent comprises a mixture of flavor components.5. The composition of wherein the lipophilic agent has a partition coefficient (octane-water) with an overall log P value of greater than about 1.5.6. The composition of claim 1 , wherein said surfactant system comprises:from about 0.5 to about 3%, by weight, of an anionic surfactant;from about 0.2 to about 3%, by weight, of a zwitterionic surfactant; andfrom about 1 to about 3%, by weight, of a nonionic surfactant.7. The composition of claim 6 , comprising:from about 0.1 to about 2%, by weight, of a structuring agent;from about 1 to about 3%, by weight, of a lipophilic agent; andfrom about 20 to about 40%, by weight, free water.8. The composition of wherein the anionic surfactant comprises sodium lauryl sulfate.9. The composition of wherein the zwitterionic surfactant comprises cocamidopropyl betaine.10. The composition of wherein the nonionic surfactant comprises poloxamer 407.11. The composition of wherein the structuring agent is xanthan gum.12. The composition of claim 1 , comprising:about 1.5%, by weight, of an anionic surfactant;about 0.75%, by weight, of a zwitterionic surfactant;about 2%, by weight, of a nonionic surfactant;about 0.85%, by weight, of a structuring agent;about 1.5%, by weight, of a lipophilic agent; andabout 28%, by weight, free water.13. The composition of wherein the lipophilic ...

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Номер записи: 93
05-12-2013 дата публикации

Mouthrinse Composition

Номер: US20130319883A1
Автор: Brunella Andre, Matur Turan, Moya Argilagos Dally, Scheffel Cornelia
Принадлежит: GABA INTERNATIONAL HOLDING AG

A mouthrinse containing chitosan or pharmaceutically acceptable acid addition salt thereof with fluoride ions, for use against erosive tooth demineralization, and kits containing chitosan or pharmaceutically acceptable acid addition salt thereof with fluoride ions, wherein one of the two active agents is comprised in a mouthrinse, are described. The mouthrinse may furthermore comprise dissolved tin, in particular stannous ions. Mouthrinses containing chitosan or pharmaceutically acceptable acid addition salt thereof with fluoride ions are tested in the treatment or prevention of erosive tooth demineralisation caused by citric acid. 1. A mouthrinse comprising dissolved chitosan or a pharmaceutically acceptable acid addition salt thereof and dissolved fluoride ions , for use against erosive tooth demineralization.2. The mouthrinse of claim 1 , wherein the use is the prevention of erosive tooth demineralisation or the treatment of teeth affected by erosive tooth demineralisation.3. The dentifrice of claim 1 , wherein the chitosan comprises unmodified chitosan.4. The mouthrinse of or or claim 1 , furthermore comprising dissolved tin.5. The mouthrinse of comprising 200 to 2000 ppm claim 4 , preferably 250 to 1000 ppm dissolved fluoride ions claim 4 , 0.05 to 5% of dissolved chitosan or a pharmaceutically acceptable acid addition salt thereof claim 4 , 150 to 1000 ppm dissolved tin claim 4 , 5 to 20% of glycerol and 0.3 to 5% of gluconate claim 4 , all % based on the mouthrinse.6. A kit comprising:a) A mouthrinse comprising dissolved chitosan or a pharmaceutically acceptable acid addition salt thereof and dissolved fluoride ions; andb1) a container containing the mouthrinse and bearing human-readable indications disclosing that the mouthrinse is for use against erosive tooth demineralization, orb2) a package containing a container, the container comprising the mouthrinse, and the package bearing human-readable indications disclosing that the mouthrinse is for use against ...

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Номер записи: 94
05-12-2013 дата публикации

Dentifrice Composition

Номер: US20130323186A1
Автор: Brunella Andre, Matur Turan, Moya Argilagos Dally, Scheffel Cornelia
Принадлежит: GABA INTERNATIONAL HOLDING AG

A dentifrice, such as toothpaste, containing chitosan or pharmaceutically acceptable acid addition salt thereof with fluoride ions, for use against erosive tooth demineralization, and kits containing chitosan or pharmaceutically acceptable acid addition salt thereof with fluoride ions, wherein one of the two active agents is comprised in a dentifrice, are described. The dentifrice in the form of toothpaste may furthermore comprise dissolved tin, in particular stannous ions. Toothpastes containing chitosan or pharmaceutically acceptable acid addition salt thereof with fluoride ions are tested in the treatment or prevention of erosive tooth demineralisation caused by citric acid. 1. A dentifrice comprising chitosan or pharmaceutically acceptable acid addition salt thereof , fluoride ions and an abrasive , for use against erosive tooth demineralization.2. The dentifrice of claim 1 , wherein the use is the prevention of erosive tooth demineralisation or the treatment of teeth affected by erosive tooth demineralisation.3. The dentifrice of or claim 1 , which is a toothpaste comprising a liquid phase claim 1 , and wherein the chitosan or pharmaceutically acceptable acid addition salt thereof and the fluoride ions are dissolved in the liquid phase.43. The dentifrice of claim 1 , claim 1 , or claim 1 , wherein the chitosan comprises unmodified chitosan.5. The dentifrice of claim 4 , comprising tin dissolved in the liquid phase.6. The dentifrice of claim 5 , wherein the use is the treatment of teeth affected by erosive tooth demineralisation or prevention of erosive tooth demineralisation and the toothpaste comprises one or more abrasives in a total amount such as to impart the toothpaste a PCR value of at least 50.7. The dentifrice of wherein the dentifrice comprises a liquid phase claim 1 , 200 to 2000 ppm claim 1 , preferably 1000 to 1800 ppm fluoride ions claim 1 , 0.05 to 1% of chitosan or a pharmaceutically acceptable acid addition salt thereof; 3000 to 4000 ppm tin ...

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Номер записи: 95
05-12-2013 дата публикации

FLAVOUR COMPOSITION COMPRISING MENTHOL AND MENTHANE CARBOXAMIDES

Номер: US20130323388A1
Автор: Bartholomew Tracy, Talsma Paul Alexander
Принадлежит: Givaudan S.A.

The invention relates to flavour compositions comprising a mixture of coolant compounds comprising menthol and a menthane carboxamide selected from N-(4-cyanomethylphenyl) p-menthanecarboxamide, 2-isopropyl-5-methyl-N-(2-(pyridin-4-yl)ethyl)cyclohexanecarboxamide, or a mixture of N-(4-cyanomethylphenyl) p-menthanecarboxamide and 2-isopropyl-5-methyl-N-(2-(pyridin-4-yl)ethyl)cyclohexanecarboxamide, wherein the total amount of menthane carboxamide is about 0.1 to 10%. 1. A flavour composition comprising a mixture of coolant compounds comprising menthol and a menthane carboxamide selected from N-(4-cyanomethyl phenyl) p-menthanecarboxamide , 2-isopropyl-5-methyl-N-(2-(pyridin-4-yl)ethyl)cyclohexanecarboxamide , or a mixture of N-(4-cyanomethylphenyl) p-menthane carboxamide and 2-isopropyl-5-methyl-N-(2-(pyridin-4-yl)ethyl)cyclohexane carboxamide , wherein the amount of menthol represents less than 50% by weight of the total flavour composition and the total amount of menthane carboxamide is about 0.1 to 10%.2. The flavour composition according to wherein the amount of menthol in the flavour composition is about 1% to 50% by weight.3. The flavour composition according to wherein the total amount of menthane carboxamide in the flavour composition is about 0.1 to 10% by weight.4. The flavour composition according to wherein the menthane carboxamide consists of N-(4-cyanomethylphenyl) p-menthanecarboxamide in an amount of 0.1 to 3% by weight of the flavour composition.5. The flavour composition according to wherein the menthane carboxamide consists of 2-isopropyl-5-methyl-N-(2-(pyridin-4-yl)ethyl)cyclohexanecarboxamide in an amount of 0.1 to 10% by weight of the flavour composition.6. The flavour composition according to wherein the menthane carboxamide consists of a mixture of N-(4-cyanomethylphenyl) p-menthanecarboxamide and 2-isopropyl-5-methyl-N-(2-(pyridin-4-yl)ethyl)cyclohexane carboxamide claim 1 , said mixture being provided in an amount of 0.1 to 13% by weight. of ...

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Номер записи: 96
12-12-2013 дата публикации

MOUTHWASH FORMULATIONS FOR USE WITH TOOTHBRUSH DELIVERY DEVICE

Номер: US20130330116A1
Автор: Arvanitidou Evangelia S., Boyd Thomas, Brown James R., Chopra Suman, Kennedy Sharon, Mello Sarita, Patel Madhusudan
Принадлежит:

Disclosed are compositions suitable for use with an oral care implement. The compositions provide improved sensory appeal, and comparable reduction in volatile sulfur compounds and antibacterial activity to advanced formula toothpaste formulations. The compositions include a high percentage of antibacterial agent and flavoring, when compared to conventional toothpastes, and some mouth washes formulations, such that only minor amounts of the composition can be delivered to the oral care implement to provide improved reduction in volatile sulfur compounds, antibacterial efficacy, and optionally a cooling sensation. 1. An oral care composition comprising:(a) 5 to 45% by weight antibacterial agent selected from copper (II) compounds, zinc ion sources, phthalic acid and salts thereof, hexetidine, octenidine, sanguinarine, benzalkonium chloride, domiphen bromide, alkylpyridinium chlorides, iodine, sulfonamides, bisbiguanides, magnolia extract, grapeseed extract, menthol, geraniol, citral, eucalyptol, augmentin, amoxicillin, tetracycline, doxycycline, minocycline, metronidazole, neomycin, kanamycin and clindamycin;(b) 5 to 70% by weight flavorant; and(c) an orally acceptable liquid carrier,wherein the composition delivers more than 5 mg of antibacterial agent to the oral cavity when less than 50 μl of composition is delivered to the oral cavity, and wherein the composition has a viscosity of 1 to 100 mPas (cps), viscosity being measured at 25° C. using a Broomfield viscosimeter employing a cone spindle at 10 rpm (2 degrees, 40 mm)2. The composition of claim 1 , wherein the orally acceptable liquid carrier comprises water.3. The composition of claim 2 , wherein the orally acceptable claim 2 , liquid carrier further comprises ethanol claim 2 , optionally wherein a ratio of water to ethanol is 0.5:1 to 20:1 claim 2 , 0.75:1 to 10:1 claim 2 , or 1:1 to 7:1.4. The composition of claim 1 , wherein the composition delivers about 7 mg of antibacterial agent to the oral cavity when ...

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Номер записи: 97
19-12-2013 дата публикации

Device and method for teeth brightening

Номер: US20130337403A1
Автор: Nikolaos Loupis, Remigio Piergallini, Shipra Rastogi
Принадлежит: VALEANT PHARMACEUTICALS INTERNATIONAL Inc

A device for applying a tooth brightening composition to a tooth includes a reservoir fluidly connected to an applicator, where applicator having a factional stress value sufficient to cause mechanical displacement of a biofilm present on a surface of the tooth; a tooth brightening composition disposed within the reservoir; and an activator configured to dispense the tooth brightening composition from the reservoir onto an exterior surface of the applicator. Alternatively or in combination with the above device, the applicator contains pores having a diameter of 0.1-1000 μm.

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Номер записи: 98
19-12-2013 дата публикации

Layered firbrous construct

Номер: US20130338791A1
Автор: Helen Autefage, Molly Morag Stevens, Seth Dylan Mccullen
Принадлежит: Helen Autefage, Molly Morag Stevens, Seth Dylan Mccullen

The present invention relates to a layered fibrous construct for use as a scaffold for repairing or replacing cartilage or cartilage-like tissue, and a process for the production thereof.

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Номер записи: 99
26-12-2013 дата публикации

FOAMING ORAL CARE FORMULATION AND SYSTEM AND METHOD OF FORMING AND USING SAME

Номер: US20130344009A1
Автор: Nanda Puneet
Принадлежит:

Oral care compositions, systems, and methods of using and forming the compositions and systems are disclosed. The composition includes a surfactant and/or a foaming agent to cause the composition to foam prior to administration to an oral cavity. The foaming composition readily and quickly reaches interstitial areas within the oral cavity and at a gum line. In addition, the foaming action makes the composition enjoyable for use by children, which, in turn, encourages compliance with use. 1. A foaming oral care composition comprising:an effective amount of one or more anticaries agents;at least one surfactant; andat least one solvent,wherein the composition foams when activated by a propellant-free pump actuator coupled to a container.2. The foaming oral care composition of claim 1 , further comprising one or more cleaning agents.3. The foaming oral care composition of claim 1 , further comprising a whitening agent.4. The foaming oral care composition of claim 1 , further comprising a moisturizing agent.5. The foaming oral care composition of claim 1 , further comprising a preservative.6. The foaming oral care composition of claim 1 , further comprising a sweetener.7. The foaming oral care composition of claim 1 , further comprising a flavorant.8. The foaming oral care composition of claim 1 , further comprising a second surfactant.9. The foaming oral care composition of claim 1 , further comprising a thickening agent.10. The foaming oral care composition of claim 1 , further comprising abrasive material.11. The foaming oral care composition of claim 10 , wherein the abrasive material comprises colloidal silica.12. The foaming oral care composition of claim 10 , wherein the abrasive material is in suspension.13. A foaming oral care system comprising a pump-actuated container and a composition according to .14. The foaming oral care system of claim 13 , wherein the composition further comprising abrasive material.15. The foaming oral care system of claim 14 , wherein ...

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Номер записи: 100