PRODUCTION METHOD FOR 1,2,3,5,6-PENTATHIEPANE

The present invention enables provision of a production method for 1,2,3,5,6-pentathiepane, the method comprising, in the following order, step A for reacting a trithiocarbonate, sulfur, and a methane dihalide together using a phase-transfer catalyst in a multilayer system having a water layer and an organic layer, step B for separating the water layer from the organic layer, and step C for stopping the reaction using an acid. 1. A method for producing 1 ,2 ,3 ,5 ,6-pentathiepane , the method comprising Steps A , B and C in this order:Step A: reacting trithiocarbonate, sulfur and methane dihalide using a phase-transfer catalyst in a multi-layer system having an aqueous layer and an organic layer;Step B: separating the aqueous layer from the organic layer; andStep C: terminating the reaction with an acid.2. The method for producing 1 claim 1 ,2 claim 1 ,3 claim 1 ,5 claim 1 ,6-pentathiepane according to claim 1 , wherein the organic layer comprises one or more selected from the group consisting of benzene claim 1 , toluene and tetrahydrofuran.3. The method for producing 1 claim 1 ,2 claim 1 ,3 claim 1 ,5 claim 1 ,6-pentathiepane according to claim 1 , wherein the organic layer comprises toluene.4. The method for producing 1 claim 1 ,2 claim 1 ,3 claim 1 ,5 claim 1 ,6-pentathiepane according to claim 1 , wherein the phase-transfer catalyst comprises a quaternary alkylammonium salt.5. The method for producing 1 claim 1 ,2 claim 1 ,3 claim 1 ,5 claim 1 ,6-pentathiepane according to claim 1 , wherein the trithiocarbonate is disodium trithiocarbonate.6. The method for producing 1 claim 1 ,2 claim 1 ,3 claim 1 ,5 claim 1 ,6-pentathiepane according to claim 1 , wherein the methane dihalide comprises dibromomethane or diiodomethane.7. The method for producing 1 claim 1 ,2 claim 1 ,3 claim 1 ,5 claim 1 ,6-pentathiepane according to claim 1 , wherein the acid is sulfuric acid.8. The method for producing 1 claim 1 ,2 claim 1 ,3 claim 1 ,5 claim 1 ,6-pentathiepane according to ...

O-PHENYL PHENOXYALKYL ACRYLATE AND METHODS FOR PRODUCING THE SAME

The present disclosure provides a method for preparing o-phenyl phenoxyalkyl acrylate, including: transesterifying an acrylate-based compound with a biphenyl alcohol compound in the absence of a solvent and in the presence of a catalyst and a polymerization inhibitor to prepare the o-phenyl phenoxyalkyl acrylate represented by the following formula (II), 2. The method of claim 1 , wherein the homogeneous catalyst is bis-(C1-C10)alkyl tin oxide.3. The method of claim 2 , wherein the bis-(C1-C10)alkyl tin oxide is at least one selected from the group consisting of dioctyltin oxide and dibutyltin oxide.4. The method of claim 2 , wherein the bis-(C1-C10)alkyl tin oxide is in an amount of from 0.5% to 1.5% by weight.5. The method of claim 1 , wherein the homogeneous catalyst is a titanate catalyst.6. The method of claim 5 , wherein the titanate catalyst is at least one selected from the group consisting of tetrabutyl titanate and tetraisopropyl titanate.7. The method of claim 5 , wherein the titanate catalyst is in an amount of from 1.5% to 3.5% by weight.8. The method of claim 1 , wherein the polymerization inhibitor is at least one selected from the group consisting of oxygen claim 1 , phenothiazine claim 1 , a phenolic compound claim 1 , and a nitroxide free-radical compound.9. The method of claim 8 , wherein the phenolic compound is 6-tert-butyl-2 claim 8 ,4-dimethylphenol claim 8 , 2-tert-butyl hydroquinone claim 8 , 2 claim 8 ,5-di-tert-butyl hydroquinone claim 8 , p-hydroxyanisole or hydroquinone.10. The method of claim 8 , wherein the nitroxide free-radical compound is piperidinol nitroxide or piperidine nitroxide phosphite.11. The method of claim 1 , wherein the polymerization inhibitor is in an amount of from 0.1% to 1.5% by weight.12. The method of claim 8 , wherein the polymerization inhibitor is the phenolic compound in an amount of from 0.5% to 1.5% by weight.13. The method of claim 1 , wherein the acrylate-based compound is selected from the group ...

Accelerator Composition for the Cure of Polyfunctional Isocyanates with Epoxy Resins

The present disclosure is related to an accelerator composition for the cure of polyfunctional isocyanates with epoxy resins comprising (a) a boron trihalide-amine complex, and (b) a quaternary ammonium or phosphonium halide as well as the use of such accelerator composition, cured isocyanate-epoxy resin products obtainable therefrom and a method of making a cured isocyanate-epoxy resin product. 1. An accelerator composition for curing polyfunctional isocyanates with epoxy resins comprising(a) a boron trihalide-amine complex, and(b) a quaternary ammonium or phosphonium halide.2. The composition according to claim 1 , wherein component (a) is a boron trichloride-amine complex.3. The composition according to claim 2 , wherein component (a) is a boron trichloride-dimethyloctylamine complex claim 2 , boron trichloride-trimethylamine complex claim 2 , boron trichloride-benzyldimethylamine complex or mixtures thereof.4. The composition according to any of the preceding claims claim 2 , wherein component (b) is a quaternary ammonium or phosphonium bromide or chloride.5. The composition according to claim 4 , wherein component (b) is benzyltriethylammoniumchloride claim 4 , tetrabutylammoniumchloride claim 4 , tetrabutylammonium bromide claim 4 , tetrabutylphosphonium chloride tetrabutylphosphonium bromide or mixtures thereof.6. The composition according to any of the preceding claims claim 4 , wherein the weight ratio of component (a) to component (b) is in the range from about 50:1 to 1:1.7. The composition according to claim 6 , wherein the weight ratio of component (a) to component (b) is about 20:1 to 5:1.8. Use of an accelerator composition according to any of the preceding claims for the cure of polyfunctional isocyanates with epoxy resin.9. The use according to claim 8 , wherein the polyfunctional isocyanate is selected from the group consisting of diphenylmethane-2 claim 8 ,4- or -4 claim 8 ,4′-diisocyanate; polyphenylene polymethylene polyisocyanate; ...

N,N,N'-Trimethyl-Bis-(Aminoethyl) Ether and its Derivatives as Catalysts for Polyurethanes

The present invention provides compounds produced by the reaction of glycidyl ethers and glycidyl esters with ether compounds including N,N,N′-trimethyl-bis-(aminoethyl) ether. N,N,N′-trimethyl-bis-(aminoethyl) ether and its derivatives can be used as polyurethane catalysts. 132-. (canceled)34. The catalyst composition of claim 33 , further comprising at least one additive selected from at least one cell stabilizer claim 33 , at least one flame retardant claim 33 , at least one chain extender claim 33 , at least one epoxy resin claim 33 , at least one acrylic resin claim 33 , at least one filler claim 33 , at least one pigment claim 33 , or any combination thereof.35. The catalyst composition of claim 33 , wherein the at least one polyol comprises at least one polyether polyol claim 33 , at least one polyester polyol claim 33 , at least one polymer polyol claim 33 , or any combination thereof.36. The catalyst composition of claim 33 , further comprising at least one member selected from the group consisting of triethylenediamine claim 33 , N-methylimidazole claim 33 , 1 claim 33 ,2-dimethylimidazole claim 33 , N-methylmorpholine claim 33 , N-ethylmorpholine claim 33 , trimethylamine N claim 33 ,N′dimethylpiperazine claim 33 , 1 claim 33 ,3 claim 33 ,5-tris(dimethylaminopropyl)hexahydrotriazine claim 33 , 2 claim 33 ,4 claim 33 ,6-tris(dimethylaminomethyl)phenol claim 33 , N-methyldicyclohexylamine claim 33 , pentamethyldipropylene triamine claim 33 , N-methyl-N′-(2-dimethylamino)-ethyl-piperazine claim 33 , tributylamine claim 33 , dimethylaminocyclohexylamine claim 33 , pentamethyldipropylene-triamine claim 33 , triethanolamine claim 33 , dimethylethanolamine claim 33 , tris(3-dimethylamino)propylamine claim 33 , and 1 claim 33 ,8 diazabicyclo[5.4.0] undecene.37. The catalyst composition of claim 33 , further comprising at least one additive selected from at least one cell stabilizer claim 33 , at least one flame retardant claim 33 , at least one epoxy resin claim ...

METHOD OF CATALYTIC OXIDATION OF LIGNITE USING OXYGEN AS OXIDANT AT ATMOSPHERIC PRESSURE

Disclosed is a method of catalytic oxidation of lignite using oxygen as an oxidant at atmospheric pressure, belonging to a method of mild oxidation of lignite. The method is used to mildly oxidize the lignite using the oxygen as the oxidant under the action of a nitroxide radical catalyst and a metal salt or metal oxide cocatalyst; the process comprises the following steps: pulverizing the lignite to 200 meshes or less, drying a pulverized coal sample at a temperature of 80° C. in vacuum for 10 h, weighing 0.5 g of the treated coal sample, sequentially adding 10 ml of acetic acid, 0.5 mmol of a catalyst and 0.15 to 0.25 mmol of a cocatalyst into a round-bottom flask, connecting a tee joint to an upper orifice of a condenser pipe, replacing oxygen in vacuum for three times so that the round-bottom flask is filled with the oxygen, keeping oxygen pressure at 0.1 MPa, reacting at a temperature of 80° C. to 120° C. for 4 to 12 h; filtering after the reaction is finished; decompressing a filtrate to remove the acetic acid, adding a small amount of ethyl acetate to dissolve, then using an excess CHN/ether solution to esterify for 10 h at room temperature, using 0.45 μm filter paper to filter, and analyzing an esterified product through a gas chromatography-mass spectrometer. The method has the advantages of using the oxygen as the oxidant, having low price, having no toxicity, and achieving environmental protection and mild conditions. 1. A method of a catalytic oxidation of a lignite using oxygen as an oxidant at atmospheric pressure for mildly oxidizing the lignite using the oxygen as the oxidant under an action of a nitroxide radical catalyst and a metal salt or a metal oxide cocatalyst , comprising:pulverizing a lignite to 200 meshes or less;drying the lignite being pulverized at a temperature of 80° C. in vacuum for 10 h;weighing 0.5 g of the lignite being dried;sequentially adding 10 ml of acetic acid, 0.5 mmol of a catalyst, and 0.15˜0.25 mmol of a cocatalyst into a ...

Zinc catalyst/additive system for the polymerization of epoxide monomers

The present invention concerns a catalyst formulation comprising: (a) a Zn catalyst comprising a Zn compound having alcoholate ligand(s) derived from one or more polyols, and (b) a catalyst additive comprising a metal compound (i) having alcoholate ligand(s) derived from one or monohydric alcohol wherein the metal is selected from: (I) group 2 metals, preferably Mg, Ca, Sr, and Ba, more preferably Mg, (II) Li, and (III) combinations of at least two metals selected from (I) and (II). The present invention also relates to a process for polymerizing an epoxide monomer, preferably ethylene oxide, comprising carrying out the process in the presence of the catalyst formulation.

PRODUCTION OF ISOCYANATE FUNCTIONAL ORGANOSILANES

Isocyanate-functional silanes are prepared in high yield by pyrolysis of an O-carbamate prepared by reaction of a dialkylcarbonate with an aminoalkyl-functional silane in the presence of a basic catalyst, where the catalyst is neutralized by an acid which has a pKof all protolysis stages of not more than 4. The neutralized or partially neutralized catalyst need not be removed prior to pyrolysis. The isocyanato-functional silanes exhibit higher storage stability as compared to those prepared from O-carbamates where catalyst neutralization is effected by weak acids. 19.-. (canceled)11. The process of claim 10 , wherein at least one acid is selected from the group consisting of halogen-containing acids and acids containing halogen and oxygen claim 10 , sulfur-containing acids claim 10 , nitrous acid and nitric acid.12. The process of claim 10 , wherein the acid is selected from among halogen-hydrogen acids having a direct halogen-oxygen bond.13. The process of claim 11 , wherein the acid is selected from among halogen-hydrogen acids having a direct halogen-oxygen bond.14. The process of claim 10 , wherein at least one acid is sulfuric acid or toluenesulfonic acid.15. The process of claim 10 , wherein the acid is added in the complete or partial neutralization in such an amount that from 0.9 to 5 mol of acidic hydrogens are present per 1 mol of basic functions in the catalyst (K).16. The process of claim 11 , wherein the acid is added in the complete or partial neutralization in such an amount that from 0.9 to 5 mol of acidic hydrogens are present per 1 mol of basic functions in the catalyst (K).17. The process of claim 12 , wherein the acid is added in the complete or partial neutralization in such an amount that from 0.9 to 5 mol of acidic hydrogens are present per 1 mol of basic functions in the catalyst (K).18. The process of claim 10 , wherein Ris an alkyl radical having 1 or 4 carbon atoms.19. The process of claim 10 , wherein Ris an alkyl radical having 1 or 4 ...

一种对苯二胺盐酸盐的合成方法

一种对苯二胺盐酸盐的合成方法，以N,N‑二甲基甲酰胺为溶剂，四甲基溴化铵为相转移催化剂，对苯二胺和氯化氢在一定条件下合成对苯二胺盐酸盐。在10℃~30℃下，向溶于对苯二胺的N,N‑二甲基甲酰胺溶液中通入氯化氢，其产品收率99.50%以上，产品纯度99.90%以上。

Antimony alcoholate catalyst composition

Carbocationic catalysts and process for using said catalysts

A carbocationic catalyst composition comprising an initiator of water, a tertiary alkyl or aralkyl halide, ester, ether, carboxylic acid, acid halide or a polymeric halide and a co-initiator of an alkoxy metal halide, is used to produce narrow molecular weight distribution olefin polymers particularly isobutylene/para-methyl-styrene copolymers.

Carbocationic catalysts and process for using said catalysts

A carbocationic catalyst composition comprising an initiator of water, a tertiary alkyl or aralkyl halide, ester, ether, carboxylic acid, acid halide or a polymeric halide and a co-initiator of an alkoxy metal halide, is used to produce narrow molecular weight distribution olefin polymers particularly isobutylene/para-methyl-styrene copolymers.

一种对苯二胺盐酸盐的合成方法

一种对苯二胺盐酸盐的合成方法，以N,N‑二甲基甲酰胺为溶剂，四甲基溴化铵为相转移催化剂，对苯二胺和氯化氢在一定条件下合成对苯二胺盐酸盐。在10℃~30℃下，向溶于对苯二胺的N,N‑二甲基甲酰胺溶液中通入氯化氢，其产品收率99.50%以上，产品纯度99.90%以上。

Carbocationic catalysts and process for using said catalysts

A carbocationic catalyst composition comprising an initiator of water, a tertiary alkyl or aralkyl halide, ester, ether, carboxylic acid, acid halide or a polymeric halide and a co-initiator of an alkoxy metal halide, is used to produce narrow molecular weight distribution olefin polymers particularly isobutylene/para-methyl-styrene copolymers.

Recovery of a tertiary amine or quaternary ammonium catalyst used in the production of a-substituted benzyl nitriles

Process for catalytically synthesizing glyphosate

一种合成草甘膦的有机催化剂，该催化剂为包括第一主族碱金属的烷氧基化合物，还包括新鲜无水甲醇、乙醇和第钾、钠金属或钾、钠的无水氢氧化物或氧化物配制或碱金属反应配制的烷氧基金属化合物，并以该烷氧基金属化合物醇溶液形式存在的一种或多种的组合。合成草甘膦的工艺，多聚甲醛或甲醛的甲醇溶液经添加有机催化剂后进行解聚反应，反应完成后加入三乙胺、甘氨酸搅拌进行加成反应；反应完成后加入亚磷酸二甲酯进行缩合反应，反应完成后加入盐酸水解，再经结晶、洗料、烘干得到草甘膦。使用特定的催化剂提高草甘膦合成反应速度及反应选择性，解聚反应速度快、反应彻底，加成反应选择性也高，草甘膦产品收率高5%以上，具有反应优势、节能优势、成本优势、环保优势。

Method for producing organic substances

The invention relates to a method for producing organic substances by converting corresponding reactants in the presence of phase transfer catalysts in an at least two-phase reaction medium containing one or several ionic liquids and water.

Novel multi-element selenide, synthetic method thereof and application thereof in photocatalytic degradation of dye

本发明公开了一种新型多元硒化物，所述化合物的化学式为HenCs[Cu 2 GeSe 5 ]，其中en为乙二胺，其骨架结构由无限延展的一维柱状[Cu 2 GeSe 5 ] 2‑ 阴离子链与分立的Cs + 阳离子和质子化的乙二胺组成。该多元硒化物晶体属单斜晶系，空间群为 P 2(1)/c，晶胞参数为： a =14.5294(4)Å, b =9.1733(3)Å， c =10.6909(3)Å， a =90.0°， β =93.2345°， γ =90.0°。经试验发现，本发明多元硒化物具有良好的光催化性能，可以有效降解染料罗丹明B等。

Method for producing trihydroxyethyl isocyanurate

一种生产三羟乙基异氰尿酸酯的方法，属于化工合成技术领域，氰尿酸与环氧乙烷在催化剂的催化作用下在有机溶剂中进行加成反应，反应结束后将反应溶液脱色过滤、降温结晶得到目的物；所述的有机溶剂为DMF，所述的催化剂为包含四甲基氯化铵和三乙胺的固液混合催化剂。本发明大大提高了产品的质量，缩短生产周期，提高了产品的收率。

Process for preparing 5-fluoro-1-methyl-3-difluoromethyl-1h-pyrazole-4-carbaldehyde

본 발명은 살진균제 제조에서 유용한 중간체인 5-플루오로-1-메틸-3-디플루오로메틸-1H-피라졸-4-카브알데히드의 신규한 제조 방법에 관련된다. The present invention relates to a novel process for the preparation of 5-fluoro-1-methyl-3-difluoromethyl-1H-pyrazole-4-carbaldehyde, which is an intermediate useful in the preparation of fungicides.

RECOVERY OF AN ORGANIC QUATERNARY AMMONIUM SALT USED AS A CATALYST

L'invention concerne un procédé de récupération d'un sel d'ammonium quaternaire organique utilisé comme catalyseur dans une réaction entre un benzylnitrile et un halogénure en présence d'un alcali. La solution réactionnelle contient un alpha -alkyl- ou alpha -phénylbenzylnitrile qui est le produit recherché, l'alcali et le catalyseur. On ajoute de l'eau (étape A) à la solution réactionnelle pour que la concentration en alcali de la phase soit de 10 % ou moins, puis on sépare la phase aqueuse contenant le sel d'ammonium quaternaire organique de la phase huileuse contenant le benzylnitrile alpha -substitué désiré. On peut ensuite traiter la phase aqueuse en ajoutant de l'alcali (étape B) puis en l'extrayant par un solvant (étape C) pour obtenir une phase organique contenant le sel d'ammonium quaternaire que l'on peut réutiliser dans le processus initial. The invention relates to a process for recovering an organic quaternary ammonium salt used as a catalyst in a reaction between a benzylnitrile and a halide in the presence of an alkali. The reaction solution contains an alpha -alkyl- or alpha -phenylbenzylnitrile which is the desired product, the alkali and the catalyst. Water (step A) is added to the reaction solution so that the alkali concentration of the phase is 10% or less, then the aqueous phase containing the organic quaternary ammonium salt is separated from the oil phase containing the Desired alpha-substituted benzylnitrile. The aqueous phase can then be treated by adding alkali (step B) and then extracting it with a solvent (step C) to obtain an organic phase containing the quaternary ammonium salt which can be reused in the process. initial.

CATALYTIC COMPOSITION COMPRISING TITANIUM AND PHOSPHORUS, ITS PREPARATION AND ITS USE FOR THE CONDENSATION OF AN EPOXIDE ON A CARBOXYLIC ACID ANHYDRIDE.

Process for the preparation of α-ethylenic compounds.

New catalysts used to facilitate SN2 and more particularly SNAr substitutions on aromatic substrates, useful for effecting exchanges between fluorine and a higher halogen or pseudo-halogen

Catalyst of specific formula is used as a catalyst for nucleophilic substitution reactions preferably aromatic substitution reactions. Catalyst of formula (I) is used as a catalyst for nucleophilic substitution reactions preferably aromatic substitution reactions. R1, R2, R3, R4, R5 and R6 = hydrocarbyl radicals; Pn (preferably the same) = metalloid group V elements of a period higher than N; and Z = group V metalloid preferably distinct from Pn, and preferably N(N, P, As, Sb). Independent claims are also included for: (1) compositions including the catalysts (I); and (2) preparation of compounds (I).

COMPOUNDS HAVING CATALYTIC ROLE IN EXCHANGES OF NUCLEOPHILIC SUBSTITUTIONS AND PROCESS FOR THE SYNTHESIS OF SUCH COMPOUNDS

Catalytic composition comprising titanium and phosphores, its preparation and its use to condense an epoxide on a carboxylic acid anhydride

PRECIS DE LA DIVULGATION L'invention a pour objet une composition catalytique comprenant du titane et du phosphore et résultant de la mise en contact d'au moins un titanate avec au moins un sel d"'onium" quaternaire d'un acide choisi dans le groupe formé par l'acide phosphorique et les acides phosphoniques de formule R7H2PO3 dans laquelle R7 est un groupe hydrocarboné ayant de 1 à 38 atomes de carbone et le reste "onium" est un reste de formule (R8R9R10R11M)+ dans laquelle M est un élément du groupe VA de la classification périodique des éléments, de préférence l'azote ou le phosphore, et R8, R9, R10 et R11, identiques ou différents, représentent chacun un atome d'hydrogène ou un groupe hydrocarboné ayant de 1 à 38 atomes de carbone. Cette composition catalytique est utilisable pour la production d'esters et de polyesters à partird'époxydes et d'anhydrides d'acides carboxyliques. PRECISION OF DISCLOSURE The subject of the invention is a catalytic composition comprising titanium and phosphorus and resulting from the contacting of at least one titanate with at least one quaternary onium salt of an acid chosen from the group formed by phosphoric acid and phosphonic acids of formula R7H2PO3 in which R7 is a hydrocarbon group having from 1 to 38 atoms of carbon and the “onium” residue is a residue of formula (R8R9R10R11M) + in which M is an element of group VA of the periodic table of elements, preferably nitrogen or phosphorus, and R8, R9, R10 and R11, identical or different, each represents a hydrogen atom or a hydrocarbon group having from 1 to 38 carbon atoms. This composition catalytic is used for the production of esters and polyesters from epoxides and anhydrides of carboxylic acids.

Method for the preparation of alkyl esters of 3,4- epoxybutyric acid

ABSTRACT Method for the preparation of an alkyl ester of 3,4-epoxybutyric acid, of formula: R being a linear or branched alkyl group, containing from 4 to 10 C atoms, wherein the corresponding vinylacetate is catalyti= cally oxidized in a biphasic liquid system comprising: a) an aqueous phase, containing H2O2 as oxidizing agent; b) an organic phase, containing said vinylacetate and a cata-lyst selected from peroxidic compounds of formula: (R1 R2 R3 R4 N)3 PW4O24 as well as, optionally, a solvent immiscible with the aqueous phase.

Process for the production of molybdenum catalysts

Polyacid-based photocatalyst and preparation method and application thereof

本申请涉及多酸基光催化剂及其制备方法和应用，多酸基光催化剂的分子式为 且具有式I所示的结构， 其中，[POM{(OCH 2 ) 3 CR 1 } 2 ] m‑ 表示修饰型多金属氧酸盐阴离子，{POM}表示多金属氧酸盐单元，R 1 选自羟基、甲基、氨基和硝基中的至少一种，m为正整数；[C 9 H 7 NR 2 ] + 表示喹啉鎓离子，R 2 选自直链状或支链状的C1～C30烷基中的至少一种。

Metal-containing, hydrogen-storing material and method for the production thereof

The invention relates to a metal-containing, hydrogen-storing material that contains a catalyst for hydrating or dehydrating the same. The catalyst is at least one organic compound. The invention also relates to a method for the production of a metal-containing, hydrogen-storing compound, which is characterised in that the metal-containing material and/or the catalyst, which are in the form of an organic compound, is/are subjected to a mechanical grinding process.

Process for the recovery of sulfonic acid ester from hydrocarbon stream

Phase transfer catalyst and process for producing poly(fullerene hydroxide)

Disclosed is a phase transfer catalyst which enables to synthesize a poly(fullerene hydroxide) having a pale color, excellent antioxidant ability and a high water-solubility, has no nitrogenated functional group other than a hydroxy group and having no impurity such as a sodium salt remaining therein, from a raw material fullerene directly, without passing through a water-insoluble fullerene hydroxide or a hydrogenated fullerene, in an one-step reaction with high efficiency. Also disclosed is a process for producing a poly(fullerene hydroxide). Specifically disclosed is a phase transfer catalyst for use in a two-liquid-phase catalytic reaction between a solution of a raw material fullerene in an organic solvent and an aqueous hydrogen peroxide for the production of a poly(fullerene hydroxide), which comprises a quaternary ammonium salt represented by the general formula: (R)4NX [wherein R's independently represent a hydrocarbon group; and X represents an anion].

Low-odor catalyst for isocyanate-derived foams and elastomers

Provided herein are catalysts useful in providing foam products which are produced using an organic poly isocyanate as a starting material. A catalyst according to the present invention includes the tris-(hydroxyethyl)methyl ammonium cation, and optionally potassium cation, in combination with a variety of possible counter anions present to maintain charge balance and for compatibility. A catalyst according to the invention is preferably used in conjunction with one or more conventional tertiary amine catalysts in a foam producing process. The foams may be polyurethane foams, polyisocyanurate foams, flexible foams, or elastomeric foams.

Catalyst composition and method for preparing amide

本发明涉及一种用于制备酰胺的催化组合物及制备酰胺的方法。本发明以包括羟胺盐、硫酸以及含氮杂环化合物的催化组合物作为催化剂，利用酮肟在该催化组合物的催化下重排生成酰胺。使用本发明的催化组合物制备酰胺，具有提高酮肟转化率，高酰胺选择率以及提升反应对水的容忍度等优点。

Method for producing 1,2,3,5,6-pentathiepane

Recycling catalyst in preparation of dimethylformamide from dimethylamine and carbon monoxide

Dimethylformamide is produced by reacting dimethylamine with carbon monoxide in the presence of sodium or other alkali metal methylate catalyst, the procedure being such that the reaction mass always contains dimethylamine in an amount of at least 0.1 wt % in excess of the stoichiometric requirements of the reaction. The effect of this is to enable the catalyst containing reaction mass to be subjected to subsequent distillation without substantial loss of dimethylformamide or of catalyst and this renders unnecessary the costly pre-distillative catalyst removal usual in prior art processes.

Method for synthesizing 4,4' -dichlorodiphenyl sulfone by sulfoxide oxidation method

本发明涉及一种亚砜氧化法合成4，4’‑二氯二苯砜的方法，其特征在于：它包括把4，4’‑二氯二苯亚砜、二氯丙烷、水、相转移催化剂投入到反应器中，加料完毕后升温至50‑95℃，缓慢滴加双氧水，继续反应3‑7小时，冷却至0‑5℃、过滤、滤饼水洗，烘干得成品4，4’‑二氯二苯砜。本发明反应时间短，物料反应彻底，产品收率高，生产成本低。

Ester interchange catalysts

Catalyst systems for polyurethane polyester foams

Provided are catalyst systems which produce flexible polyurethane polyester foams that are color stable, are lower in odor, and uses less catalysts than current most commonly practiced technology. The use of lower amounts of catalysts with low vapor pressure reduces worker exposure to alkaline corrosive materials, reduces pollution through less pounds of volatile organic chemicals (VOC's) and is less expensive.

Preparation of 5-ethylidenebicyclo(2.2.1)hept-2-enes

METHOD FOR THE RECOVERY OF ORGANIC QUATERNARY AMMONIC SALT-BASED CATALYST FOR THE PREPARATION OF REPLACED BENZYL NITRILS

Zinc catalyst/additive system for the polymerization of epoxide monomers

The present invention concerns a catalyst formulation comprising: (a) a Zn catalyst comprising a Zn compound having alcoholate ligand(s) derived from one or more polyols, and (b) a catalyst additive comprising a metal compound (i) having alcoholate ligand(s) derived from one or monohydric alcohol wherein the metal is selected from: (I) group 2 metals, preferably Mg, Ca, Sr, and Ba, more preferably Mg, (II) Li, and (III) combinations of at least two metals selected from (I) and (II). The present invention also relates to a process for polymerizing an epoxide monomer, preferably ethylene oxide, comprising carrying out the process in the presence of the catalyst formulation.

Patent FR2391772B1

Preparation of 5-ethylidenebicyclo(2.2.1)hept-2-enes

5-Vinylbicyclo(2.2.1)hept-2-enes heated in the presence of a titanium catalyst system are isomerized to 5ethylidenebicyclo(2.2.1)hept-2-enes. The catalyst system of this invention comprises a titanium compound, an alkali metal, and a cyclopentadienyl magnesium halide. The catalyst system is highly efficient and capable of rapidly isomerizing 5vinylbicyclo(2.2.1)hept-2-enes. 5-Ethylidenebicyclo(2.2.1)hept-2enes are useful comonomers for polymerization with Alpha olefins such as ethylene and propylene.

Metal-containing, hydrogen storage material and process for its preparation

Es wird ein metallhaltiger, wasserstoffspeichernder Werkstoff vorgeschlagen, der zu seiner Hydrierung oder Dehydrierung ein Katalysationsmittel enthält. Das Katalysationsmittel ist wenigstens eine organische Verbindung. Ein Verfahren zur Herstellung einer derartigen metallhaltigen, wasserstoffspeichernden Verbindung zeichnet sich dadurch aus, daß der metallhaltige Werkstoff und/oder das Katalysationsmittel in Form einer organischen Verbindung einem mechanischen Mahlvorgang unterworfen wird bzw. werden. It a metal-containing, hydrogen-storing material is proposed, which is a catalysing agent for its hydrogenation or dehydrogenation contains. The catalysing agent is at least one organic compound. A method for producing such a metal-containing, hydrogen-storing Connection is characterized in that the metal-containing material and / or the catalysing agent in the form of an organic compound subjected to a mechanical grinding process or be.

Catalytic composition comprising titanium and phosphorus, preparation and use thereof for the condensation of an epoxyde with carboxylic acid anhydride

Catalytic composition comprising titanium and phosphorus and resulting from bringing at least one titanate into contact with at least one quaternary "onium" salt of an acid chosen from the group consisting of phosphonic acid and phosphonic acids of formula R<7>H2PO3 in which R<7> is a hydrocarbon group containing from 1 to 38 carbon atoms and the "onium" residue is a residue of formula (R<8>R<9>R<10>R<11>M)<+> in which M is an element of group VA of the Periodic Classification of the elements, preferably nitrogen or phosphorus, and each of R<8>, R<9>, R<10> and R<11>, which are identical or different, denotes a hydrogen atom or a hydrocarbon group containing from 1 to 38 carbon atoms. <??>This catalytic composition can be employed for the production of esters and polyesters from epoxides and carboxylic acid anhydrides. <IMAGE>

New amide derivatives of cinchona alkaloids, method of their preparation and their use in asymmetric phase transfer reactions

Przedmiotem wynalazku jest pochodna amidowa alkaloidu chinowca o Wzorze 1 oraz o Wzorze 3. Wynalazek dotyczy również sposobów wytwarzania pochodnej amidowej alkaloidu chinowca określonej Wzorem 1 oraz Wzorem 3, a także jej zastosowanie jako katalizatora w asymetrycznej reakcji zachodzącej w warunkach przeniesienia fazowego (PTC). The invention relates to an amide derivative of a quinoa alkaloid of Formula 1 and Formula 3. The invention also relates to methods for the preparation of an amide derivative of a cinchona alkaloid as defined by Formula 1 and Formula 3, as well as its use as a catalyst in an asymmetric phase transfer reaction (PTC).

Process for preparing omega-halocarboxylic nitriles

Low-Odor Catalyst for Isocyanate-Derived Foams and Elastomers

Provided herein are catalysts useful in providing foam products which are produced using an organic poly isocyanate as a starting material. A catalyst according to the present invention includes the tris-(hydroxyethyl)methyl ammonium cation, and optionally potassium cation, in combination with a variety of possible counter anions present to maintain charge balance and for compatibility. A catalyst according to the invention is preferably used in conjunction with one or more conventional tertiary amine catalysts in a foam producing process. The foams may be polyurethane foams, polyisocyanurate foams, flexible foams, or elastomeric foams.

Method for preparing 1-ferrocenyl-3-aryl-3-diacetyl methylene-acetone

本发明公开了一种制备1‑二茂铁基‑3‑芳基‑3‑二乙酰基次甲基‑丙酮的方法：于干燥的三口烧瓶中，加入氯化胆碱，尿素，于80℃搅拌至透明溶液，得到低共熔溶剂；将其冷至室温，加入二茂铁基查尔酮，2,4‑戊二酮，缓慢升温，回流反应，TLC监测至反应结束；将反应混合液冷至室温，加入少量水，立即有固体析出，抽滤，滤饼用水洗，干燥即得1‑二茂铁基‑3‑芳基‑3二乙酰基次甲基‑丙酮；滤液浓缩回收得到的低共熔溶剂（DES），可以重复使用5次，且其催化活性没有明显降低，其中。本发明操作简单，反应时间短，且产率高后处理简单，同时催化剂可回收利用，降低了反应成本。

Recovery of catalyst

An organic quaternary ammonium salt used as a catalyst in a reaction between a benzylnitrile and a halide in the presence of an alkali to obtain an alpha -alkyl- or alpha -phenyl-benzylnitrile, is recovered effectively from the reaction solution containing the alpha -alkyl- or alpha -phenyl-benzylnitrile, the alkali and the catalyst, by adding water to the reaction solution to make the alkali concentration of the water layer 10% by weight or below, and then separating the water layer containing the organic quaternary ammonium salt from the oil layer containing the alpha -alkyl- or alpha -phenyl-benzylnitrile.

Use of dendrimeric-type macromolecules as catalysts or coadjuvants in phase transfer catalysis reactions

The present invention concerns the use of dendrimeric-type branched macromolecules, comprising polyoxaalkylene chains, as catalysts or coadjuvants of phase transfer catalysis reactions.

Bis-quarternary cinchona alkaloid salts as asymmetric phase transfer catalysts

FIELD: chemistry.SUBSTANCE: invention relates to the field of organic chemistry, namely to the bis-quaternary salt of an alkaloid of formula (II), where Ris ethyl or vinyl, Ris hydrogen or methoxy, Rand Rare defined as follows: (I) Rrepresents:, and Ris allyl; or (II) Rrepresents:, and Rrepresents:; or (II) Rrepresents:, and Rrepresents:;;;; or CH; and X and Y independently are halide anions. Invention also relates to particular bis-quaternary alkaloid salts of formula (II).(II).EFFECT: technical result: new bis-quaternary salts of the alkaloid of the formula (II), useful as asymmetric interphase catalysts, were obtained.6 cl, 4 tbl, 2 ex

Catalyst for asymmetric induction

ABSTRACT A CATALYST FOR ASYMMETRIC INDUCTION Optically active cyanohydrins are prepared by addition of hydrogen cyanide to aldehydes in the presence of catalysts which comprise the dipeptide derivative represented by the formula [I] wherein R1 represents an isopropyl group, an isobutyl group, a sec-butyl group, a tert-butyl group, a methyl group, a benzyl group or a phenyl qroup, R2 represents a benzyl group, an indol-3-ylmethyl group, an isopropyl group, an isobutyl group or a phenyl group, R3 represents a lower alkoxy group, a hydroxy group or a mono- or di-lower alkylamino group, R4 represents a hydrogen atom, or R2 and R4 are bonded together at their terminals to form a propylene group, R5, R6, R7 and R8 are the same or different, and each represents a hydrogen atom, a halogen atom, a lower alkyl group or a lower alkoxy group or R5 and R6, R6 and R7, or R7 and R8 are bonded together at their terminals to form CH=CH-CH=CH or OCH2O, and * denotes an absolute configuration of S or R, and a titanium (IV) alkoxide.

Method for producing organic substances

The invention relates to a method for producing organic substances by converting corresponding reactants in the presence of phase transfer catalysts in an at least two-phase reaction medium containing one or several ionic liquids and water.

一种l-抗坏血酸-2-单磷酸酯钠盐合成方法

本发明涉及维生素衍生物技术领域，尤其涉及一种L‑抗坏血酸‑2‑单磷酸酯钠盐合成方法，将L‑抗坏血酸、三偏磷酸钠、催化剂、氢氧化钠分散在去离子水中，进行酯化反应，后处理得到产物；所述催化剂为(TBAC l)‑(CaCl 2 ) 2 。本发明的有益效果是：发明人开发了新的催化剂(TBAC l)‑(CaCl 2 ) 2 ，过量的L‑抗坏血酸与三偏磷酸钠进行磷酯化反应，后处理采用最常规的甲醇析出和重结晶的方法获得了含量高达99％的单磷酸酯盐，避免了使用如丙酮、吡啶这些环保处理很难的化学助剂，制备的产品的稳定性好、原料易得、操作简单、反应条件温和、反应时间短、重现性好、用于析出固体的低碳醇可循环套用、节约原料及动力费用等优点。

含双（三甲硅基）的杂环化合物的合成方法

含双(三甲硅基)的杂环化合物的合成方法，属于含双(三甲硅基)的杂环化合物合成的技术领域，包括：首先采用双(三氯甲基)碳酸酯、乙二胺、氢氧化钠水溶液、氯仿和负载催化剂制备得到2‑咪唑烷酮；或，乙二胺、乙醇、蒸馏水、负载催化剂、二硫化碳，盐酸，制备得到亚乙基硫脲；其次将三甲基氯硅烷溶于有机溶剂，通入氨气，加热至回流，至不再有白色沉淀产生，过滤，得到滤液；再将原料2‑咪唑烷酮或亚乙基硫脲溶解得到原料液，加入硫酸铵，再逐滴加入滤液，加热回流5‑6h，冷却至室温，过滤，获得产物；所述原料与三甲基氯硅烷的摩尔比为1:(2.1‑2.5)，硫酸铵的质量为原料的1.5‑2％；本发明制备方法简单，收率高。

Production method for 1,2,3,5,6-pentathiepane

The present invention enables provision of a production method for 1,2,3,5,6-pentathiepane, the method comprising, in the following order, step A for reacting a trithiocarbonate, sulfur, and a methane dihalide together using a phase-transfer catalyst in a multilayer system having a water layer and an organic layer, step B for separating the water layer from the organic layer, and step C for stopping the reaction using an acid.

Process of making derivatives of substituted morpholines

Provided here are methods of making derivatives and prodrugs of substituted morpholines or pharmaceutically acceptable salts thereof. Further provided are methods of making derivatives and prodrugs of substituted morpholines having the following chemical structure: (IIf)

一种二异氰酸酯三聚体的制备方法、催化剂及其制备方法

本发明公开了一种二异氰酸酯三聚体的制备方法、催化剂及其制备方法。该方法包括以二异氰酸酯为原料，在催化剂的存在下，使所述二异氰酸酯反应生成所述二异氰酸酯三聚体的步骤，所述催化剂包括载体和活性组分，所述载体包括碱土金属盐改性的层状无机硅酸盐材料，所述活性组分包括季铵盐或季铵碱。本发明的制备方法可以获得粘度较低、色度低、储存稳定性好的二异氰酸三聚体产品。

一种高比表面积的负载型催化剂的制备方法及其在对硝基苯胺合成中的应用

本发明公开了一种高比表面积的负载型催化剂的制备方法，包括以下步骤：将多孔纳米氧化硅分散在去离子水中，然后冰水浴条件下加入苯胺单体，混合均匀后加入过硫酸铵溶液，搅拌反应，反应结束后将反应液过滤，并采用去离子水洗涤沉淀，干燥，干燥后的固体置于马弗炉内惰性气氛下煅烧处理，制得氮掺杂碳层包覆的纳米氧化硅；将上述制得氮掺杂碳层包覆的纳米氧化硅加入到相转移催化剂的分散液中，吸附处理，之后干燥，得到高比表面积的负载型催化剂。本发明制得的负载型催化剂比表面积大，催化活性高，用于对硝基苯胺合成时在很大程度上改善了目标产品的收率和纯度，且催化剂用量少，便于回收，大大提高了产品的生产成本。

一种高比表面积的负载型催化剂的制备方法及其在对硝基苯胺合成中的应用

本发明公开了一种高比表面积的负载型催化剂的制备方法，包括以下步骤：将多孔纳米氧化硅分散在去离子水中，然后冰水浴条件下加入苯胺单体，混合均匀后加入过硫酸铵溶液，搅拌反应，反应结束后将反应液过滤，并采用去离子水洗涤沉淀，干燥，干燥后的固体置于马弗炉内惰性气氛下煅烧处理，制得氮掺杂碳层包覆的纳米氧化硅；将上述制得氮掺杂碳层包覆的纳米氧化硅加入到相转移催化剂的分散液中，吸附处理，之后干燥，得到高比表面积的负载型催化剂。本发明制得的负载型催化剂比表面积大，催化活性高，用于对硝基苯胺合成时在很大程度上改善了目标产品的收率和纯度，且催化剂用量少，便于回收，大大提高了产品的生产成本。

이온성 액체를 이용한 2,4,6-트리스(하이드록시페닐)-1,3,5-트리아진 유도체의 제조방법

이온성 액체를 이용한 2,4,6-트리스(하이드록시페닐)-1,3,5-트리아진 유도체의 제조방법을 개시한다. 상기 2,4,6-트리스(하이드록시페닐)-1,3,5-트리아진 유도체의 제조방법은 4차 암모늄 화합물 및 금속 할로겐화물을 포함하는 루이스 산 이온성 액체를 촉매로 사용함으로써 고온에서 짧은 반응시간 동안 고수율 및 고순도로 2,4,6-트리스(하이드록시페닐)-1,3,5-트리아진 유도체를 제조할 수 있다. 또한, 상기 루이스 산 이온성 액체는 재사용이 가능하고, 상기 루이스 산 이온성 액체를 재사용할 때에도 우수한 수율 및 순도의 2,4,6-트리스(하이드록시페닐)-1,3,5-트리아진 유도체를 제조할 수 있다.

이온성 액체를 이용한 2,4,6-트리스(하이드록시페닐)-1,3,5-트리아진 유도체의 제조방법

이온성 액체를 이용한 2,4,6-트리스(하이드록시페닐)-1,3,5-트리아진 유도체의 제조방법을 개시한다. 상기 2,4,6-트리스(하이드록시페닐)-1,3,5-트리아진 유도체의 제조방법은 4차 암모늄 화합물 및 금속 할로겐화물을 포함하는 루이스 산 이온성 액체를 촉매로 사용함으로써 고온에서 짧은 반응시간 동안 고수율 및 고순도로 2,4,6-트리스(하이드록시페닐)-1,3,5-트리아진 유도체를 제조할 수 있다. 또한, 상기 루이스 산 이온성 액체는 재사용이 가능하고, 상기 루이스 산 이온성 액체를 재사용할 때에도 우수한 수율 및 순도의 2,4,6-트리스(하이드록시페닐)-1,3,5-트리아진 유도체를 제조할 수 있다.

Metodo per il recupero di catalizzatore a base di sale ammonico quaternario organico per la preparazionedi benzilnitrili sostituiti

Composizioni supportate a base di tungsteno o molibdeno,procedimento per il loro ottenimento e proprieta' come catalizzatori eterogenei di ossidazione

Metodo per la preparazione di 3,4-epossibutirrati alchilici.

Process of making derivatives of substituted morpholines

Provided here are methods of making derivatives and prodrugs of substituted morpholines or pharmaceutically acceptable salts thereof. Further provided are methods of making derivatives and prodrugs of substituted morpholines having the following chemical structure:

一种高纯度2,6-二氟苯甲酰胺的制备工艺

一种高纯度2,6‑二氟苯甲酰胺的制备工艺，该制备工艺以2,6‑二氟苯腈为原料，加入水和季铵盐相转移催化剂，形成混合溶液，向溶液中同时开始双滴加双氧水及无机碱溶液，并控制同时滴加结束，保温至反应结束；降温结晶、过滤，得到2,6‑二氟苯甲酰胺粗品；粗品经水打浆、过滤、干燥得到2,6‑二氟苯甲酰胺产品。本发明工艺具有含量高、收率高、三废少、安全性强等优点，是一条选择性高、经济性强、对环境友好的绿色工艺，对工业生产有巨大的指导意义。

Catlysts for inducing assymmetry

Katalysator zur asymmetrischen Induktion.

Process for producing optically active cyanohydrines and catlysts suitable for inducing asymmetry

Process for producing catalysts suitable for inducing asymmetry and process for producing optically active cyanohydrines using said catalysts

Un catalizador para induccion asimetrica.

CATALIZADORES PARA LA PRODUCCION DE CIANHIDRINAS OPTICAMENTE ACTIVAS MEDIANTE LA ADICION DE CIANURO DE HIDROGENO A ALDEHIDOS QUE SE COMPONEN DE UN ALCOXIDO DE TITANIO (IV) Y UN DERIVADO DE DIPEPTIDO DE FORMULA (I) DONDE R1 ES ISOPROPILO, ISOBUTILO, SEC-BUTILO, TERC-BUTILO, METILO, BENCILO O FENILO, R3 ES UN ALKOXI INFERIOR, HIDROXILO O MONOR, Y ADEMAS R4 ES HIDROGENO Y R2 ES BENCILO, INDOL-3-ILMETILO, ISOPROPILO, ISOBUTILO O FENILO, O R2 Y R4 JUNTOS FORMAN -CH2-CH=CH Y CADA UNO ES HIDROGENO, HALOGENO, ALKILO INFERIOR O ALCOHOXILO INFERIOR, O R5 Y R6 O R6 Y R7, O R7 Y R8 JUNTOS FORMAN -CH=CH-CH=CH TIENE UNA CONFIGURACION ABSOLUTA DE S O R.

Katalysator zur asymmetrischen Induktion.

비대칭 상 이동 촉매로서의 비스-4급 신코나 알칼로이드 염

본 발명은 신규 비스-4급 신코나 알칼로이드 염 및 비대칭 상 이동 촉매작용에서의 비스-4급 신코나 알칼로이드 염의 용도에 관한 것이다. 본 발명은 신규 비스-4급 신코나 알칼로이드 염 및 비대칭 상 이동 촉매작용에서의 비스-4급 신코나 알칼로이드 염의 용도에 관한 것이다. 특정 기질 상에서 및 특정 반응 조건 하에서, 본 발명자들은 비대칭 상 이동 촉매작용에서 비스-4급 신코나 알칼로이드 염의 사용이 놀랍게도 모노-4급 촉매와 비교하여 더 활성이고 효율적인 방법을 제공한다는 것을 발견하였다.

Sal de alcaloide bisquaternário

sal de alcaloide bisquaternário a invenção é direcionada aos novos sais de alcaloides da quina bisquaternários e ao uso dos sais de alcaloides da quina bisquaternários na catálise de transferência de fase assimétrica.

Bis-quarternary cinchona alkaloid salts as asymmetric phase transfer catalysts

The invention is directed to novel bis-quarternary cinchona alkaloid salts and the use of bis-quarternary cinchona alkaloid salts in asymmetric phase transfer catalysis. The present invention is directed to novel bis-quarternary cinchona alkaloid salts and the use of bis-quartenary cinchona alkaloid salts in asymmetric phase transfer catalysis. On certain substrates and under specific reaction conditions, the inventors have discovered that the use of bis-quarternary cinchona alkaloid salts in asymmetric phase transfer catalysis surprisingly provides for a more active and efficient process as compared to mono-quarternary catalysts.

비대칭 상 이동 촉매로서의 비스-4급 신코나 알칼로이드 염

본 발명은 신규 비스-4급 신코나 알칼로이드 염 및 비대칭 상 이동 촉매작용에서의 비스-4급 신코나 알칼로이드 염의 용도에 관한 것이다. 본 발명은 신규 비스-4급 신코나 알칼로이드 염 및 비대칭 상 이동 촉매작용에서의 비스-4급 신코나 알칼로이드 염의 용도에 관한 것이다. 특정 기질 상에서 및 특정 반응 조건 하에서, 본 발명자들은 비대칭 상 이동 촉매작용에서 비스-4급 신코나 알칼로이드 염의 사용이 놀랍게도 모노-4급 촉매와 비교하여 더 활성이고 효율적인 방법을 제공한다는 것을 발견하였다.

不斉相間移動触媒としてのビス四級シンコナアルカロイド塩

本発明は、新規なビス四級シンコナアルカロイド塩および不斉相間移動触媒反応におけるビス四級シンコナアルカロイド塩の使用に関する。本発明は、新規なビス四級シンコナアルカロイド塩、および不斉相間移動触媒反応におけるビス四級シンコナアルカロイド塩の使用に関する。特定の基質および特定の反応条件下で、本発明者らは、不斉相間移動触媒反応におけるビス四級シンコナアルカロイド塩の使用が、驚くことにモノ四級触媒と比較してより高活性かつ効果的なプロセスを提供することを見出した。

Bis-quarternary cinchona alkaloid salts as asymmetric phase transfer catalysts

Sales de alcaloide de cinchona bis-cuaternarias como catalizadores de transferencia de fase asimetrica.

La invención está dirigida a sales de alcaloide de cinchona bis-cuaternarias novedosas y al uso de las sales de alcaloide de cinchona bis-cuaternarias en catálisis de transferencia de fase asimétrica; la presente invención está dirigida a sales de alcaloide de cinchona bis-cuaternarias novedosas y al uso de las sales de alcaloide de cinchona bis-cuaternarias en catálisis de transferencia de fase asimétrica sobre ciertos sustratos y bajo condiciones de reacción específicas, los inventores han descubierto que el uso de las sales de alcaloide de cinchona bis-cuaternarias en catálisis de transferencia de fase asimétrica provee de manera sorprendente un procedimiento más activo y eficiente en comparación con catalizadores mono-cuaternarios.

Bis-quarternary cinchona alkaloid salts as asymmetric phase transfer catalysts

OF THE DISCLOSURE The invention is directed to novel bis-quarternary cinchona alkaloid salts and the use of bis-quartemary cinchona alkaloid salts in asymmetric phase transfer catalysis. 5

Бисчетвертичные соли алкалоида хинного дерева в качестве асимметрических межфазных катализаторов

1. Бисчетвертичные соли алкалоида хинного дерева, имеющие химическую структуру формулы Iгде Rвыбирают из этила и винила,Rвыбирают из водорода и метокси,Rи Rнезависимо выбирают из группы, состоящей из С-алкила, С-алкенила, С-алкинила, С-циклоалкила, арила, гетероарила, -С-алкиларила и -С-алкилгетероарила, где С-алкил, С-алкенил, С-алкинил, С-циклоалкил, арил, гетероарил и арильные и гетероарильные части -С-алкиларила и -С-алкилгетероарила необязательно замещены одним-пятью заместителями, независимо выбираемыми из R,Rвыбирают из группы, состоящей из водорода, С(О)R, C(O)OR, CONRR' и С-алкила,Rвыбирают из группы, состоящей из С-алкила, С-галогеналкила, арила, С-алкокси, гидрокси, CN, COR, CONRR', SR, SOR, SOR, PR, PO(OR), PO(OR)(NRR'), PO(NRR'), P(OR), P(OR)(NRR'), P(NRR'), SiRR'R”, B(OR), C(O)R, NRR', NOи галогена,каждый R, R' и R” независимо выбирают из группы, состоящей из водорода, С-алкила, гидроксила, С-алкокси, арила, гетероарила, -СН-арила, -СН-гетероарила, икаждый Х и Y независимо означают анионы, выбираемые из группы, состоящей из галогенида, ОН, HSO, SO, BF, SbF, карбоксилата, карбоната, гидрокарбоната, NO, сульфоната, гексафторфосфата, фосфата, гидрофосфата и перхлората,для применения в качестве межфазного катализатора при стереоселективном образовании связи углерод-углерод, углерод-гетероатом или углерод-галогенид в субстрате в двухфазной среде, содержащей водную фазу и органическую фазу, или в мицеллярной среде.2. Бисчетвертичные соли алкалоида хинного дерева по п. 1 для применения в качестве межфазного катализатора в одной из следующих асимметрических реакций:(1) алкилирование с помощью электрофильного алкилирующего агента,(2) присоединение по Михаэлю при использовании олефина с недостатком электронов,(3) альдольная конденсация при использовании альдегида,(4) реакция Манниха при использовани

Composizioni supportate a base di tungsteno o molibdeno, procedimento per il loro ottenimento e proprieta' come catalizzatori eterogenei di ossidazione

Asymmetric phase transfer catalysis

The invention relates to a process for stereoselectively producing a compound of Formula A wherein Q, R A and R B and PG are as defined in the description and wherein the reaction takes place in the presence of a bis-quaternary cinchona alkaloid salt phase transfer catalyst.

一种利用相转移催化剂合成异戊基黄原酸盐的方法

本发明公开了一种利用相转移催化剂合成异戊基黄原酸盐的方法，该方法的具体过程为：以异戊醇、二硫化碳和氢氧化钠/氢氧化钾为原料，在相转移催化剂的作用下，在28℃～40℃下进行反应，然后经干燥得到异戊基黄原酸盐。本发明利用相转移催化剂提高了亲核反应速率，促进了氢氧化钠/氢氧化钾进入液相体系异戊醇和二硫化碳中并进行反应，解决了溶剂法合成异戊基黄原酸盐中原料呈非均一相反应的难题，提高了反应速率，从而提高了异戊基黄原酸盐的品位，减少了副反应的发生，缩短了合成时间，并且解决了产品粘度太大无法成粉造粒的难题。

Method of synthesizing diols

含双（三甲硅基）的杂环化合物的合成方法

含双(三甲硅基)的杂环化合物的合成方法，属于含双(三甲硅基)的杂环化合物合成的技术领域，包括：首先采用双(三氯甲基)碳酸酯、乙二胺、氢氧化钠水溶液、氯仿和负载催化剂制备得到2‑咪唑烷酮；或，乙二胺、乙醇、蒸馏水、负载催化剂、二硫化碳，盐酸，制备得到亚乙基硫脲；其次将三甲基氯硅烷溶于有机溶剂，通入氨气，加热至回流，至不再有白色沉淀产生，过滤，得到滤液；再将原料2‑咪唑烷酮或亚乙基硫脲溶解得到原料液，加入硫酸铵，再逐滴加入滤液，加热回流5‑6h，冷却至室温，过滤，获得产物；所述原料与三甲基氯硅烷的摩尔比为1:(2.1‑2.5)，硫酸铵的质量为原料的1.5‑2％；本发明制备方法简单，收率高。

Process of making derivatives of substituted morpholines

Provided here are methods of making derivatives and prodrugs of substituted morpholines or pharmaceutically acceptable salts thereof. Further provided are methods of making derivatives and prodrugs of substituted morpholines having the following chemical structure:

Process of making derivatives of substituted morpholines

Provided here are methods of making derivatives and prodrugs of substituted morpholines or pharmaceutically acceptable salts thereof. Further provided are methods of making derivatives and prodrugs of substituted morpholines having the following chemical structure:

Process of making derivatives of substituted morpholines

Provided here are methods of making derivatives and prodrugs of substituted morpholines or pharmaceutically acceptable salts thereof. Further provided are methods of making derivatives and prodrugs of substituted morpholines having the following chemical structure: (IIf)

Trägerstützte Molybdän oder Wolfram Zusammensetzungen, Verfahren zur ihrer Herstellung und Verwendung als heterogene Oxydationskatalysatoren

Asymmetric phase transfer catalysis

The invention relates to a process for stereoselectively producing a compound of Formula Awherein Q, R^A and R^B and PG are as defined in the description and wherein the reaction takes place in the presence of a bis-quaternary cinchona alkaloid salt phase transfer catalyst.

Regeneration of ionic liquid catalyst using a regeneration metal in the presence of added hydrogen

A process for regenerating a used acidic ionic liquid catalyst comprising contacting the used ionic liquid catalyst with at least one 'regeneration' metal in a regeneration zone in the presence of added hydrogen under regeneration conditions for a time sufficient to increase the activity of the ionic liquid catalyst is described. In one embodiment, regeneration is conducted in the presence of a hydrocarbon solvent.

Diol-Synthese

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Verfahren zur synthese vicinaler diole

Werkwijze voor de bereiding van vicinale diolen door oxydatie van alkenen met organische hydroperoxyden.

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Procede de synthese de diols